Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein antigen binding

LPA PLG ITGA4 EP300

3.98e-0716794GO:1990405
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.55e-052792GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.55e-052792GO:0044017
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

BRPF3 CREBBP EP300

2.62e-0515793GO:0010484
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

4.62e-053792GO:0043993
GeneOntologyMolecularFunctionreceptor ligand inhibitor activity

LRRC32 LTBP1

9.23e-054792GO:0141069
GeneOntologyMolecularFunctionacetyltransferase activity

BRPF3 DBT CREBBP EP300

7.73e-04104794GO:0016407
GeneOntologyCellularComponentseptin complex

SEPTIN5 SEPTIN4 SEPTIN1

1.84e-0514793GO:0031105
GeneOntologyCellularComponentseptin ring

SEPTIN5 SEPTIN4 SEPTIN1

1.84e-0514793GO:0005940
GeneOntologyCellularComponentseptin cytoskeleton

SEPTIN5 SEPTIN4 SEPTIN1

2.81e-0516793GO:0032156
GeneOntologyCellularComponentextracellular matrix

NDNF ADAMTS3 P3H1 LPA LRRC32 LTBP1 PLG CTSZ TNFRSF11B

8.12e-04656799GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NDNF ADAMTS3 P3H1 LPA LRRC32 LTBP1 PLG CTSZ TNFRSF11B

8.30e-04658799GO:0030312
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

3.35e-052302HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

3.35e-052302HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

3.35e-052302HP:0001042
HumanPhenoHydrocele testis

ADAMTS3 ZMYM2 CREBBP EP300

5.05e-0536304HP:0000034
HumanPhenoHypoplastic aortic arch

BCOR CREBBP EP300

6.42e-0514303HP:0012304
HumanPhenoClinodactyly of the 5th finger

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

8.68e-054203010HP:0004209
HumanPhenoClinodactyly of hands

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

8.86e-054213010HP:0001157
HumanPhenoDeviation of the 5th finger

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

8.86e-054213010HP:0009179
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

1.00e-043302HP:0008752
HumanPhenoPhobia

CREBBP EP300

1.00e-043302HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

1.00e-043302HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

1.00e-043302HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

1.00e-043302HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

1.00e-043302HP:0005895
HumanPhenoSupernumerary tooth

ADAMTS3 EHMT1 BCOR CREBBP EP300

1.18e-0485305HP:0011069
HumanPhenoRadial deviation of finger

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

1.50e-044483010HP:0009466
HumanPhenoFinger clinodactyly

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

1.61e-044523010HP:0040019
HumanPhenoRadial deviation of the hand or of fingers of the hand

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

1.74e-044563010HP:0009485
HumanPhenoTrichiasis

CREBBP EP300

2.00e-044302HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

2.00e-044302HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

2.00e-044302HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

2.00e-044302HP:0006200
HumanPhenoVascular ring

CREBBP EP300

2.00e-044302HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

2.00e-044302HP:0031207
HumanPhenoSelf-mutilation

EHMT1 BCOR CREBBP EP300

2.02e-0451304HP:0000742
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

3.32e-045302HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

3.32e-045302HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

3.32e-045302HP:0030421
HumanPhenoAbnormal 5th finger morphology

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

4.30e-045093010HP:0004207
HumanPhenoAortic valve stenosis

EHMT1 LTBP1 BCOR CREBBP EP300

4.50e-04113305HP:0001650
HumanPhenoAbnormal number of teeth

NDNF KCNB1 ADAMTS3 FEZF1 EHMT1 BCOR CREBBP STAG2 EP300

4.90e-04421309HP:0006483
HumanPhenoLarge foramen magnum

CREBBP EP300

4.96e-046302HP:0002700
HumanPhenoDeviation of finger

EHMT1 ZMYM2 PLAG1 LTBP1 SIK3 BCOR CREBBP STAG2 EP300 CASZ1

6.62e-045373010HP:0004097
HumanPhenoDeviated nasal septum

CREBBP EP300

6.91e-047302HP:0004411
HumanPhenoFunctional abnormality of male internal genitalia

CFAP47 NDNF ADAMTS3 FEZF1 P3H1 DNAH17 EHMT1 ZMYM2 CRPPA PLAG1 LTBP1 BCOR CREBBP EP300 CASZ1 DNAH11

7.57e-0412693016HP:0000025
HumanPhenoUnsteady gait

SLC6A1 KCNB1 CRPPA PLG BCOR CREBBP STAG2 EP300

8.01e-04357308HP:0002317
MousePhenoabnormal mammary gland connective tissue morphology

LPA PLG

1.63e-052572MP:0009507
MousePhenoectropion

LPA PLG

1.63e-052572MP:0006164
MousePhenoesophageal ulcer

LPA PLG

1.63e-052572MP:0004547
MousePhenoduodenal ulcer

LPA PLG

1.63e-052572MP:0003273
MousePhenoperianal ulcer

LPA PLG

1.63e-052572MP:0005035
MousePhenoincomplete somite formation

EHMT1 RRN3P2 BCOR EP300

2.99e-0544574MP:0001689
MousePhenoperimembraneous ventricular septal defect

ADAMTS3 ACTN4 LTBP1 CREBBP EP300

3.54e-0592575MP:0010418
MousePhenoabnormal interventricular septum membranous part morphology

ADAMTS3 ACTN4 LTBP1 CREBBP EP300

3.73e-0593575MP:0008823
MousePhenoabsent cornea epithelium

LPA PLG

4.89e-053572MP:0020856
MousePhenoventricular septal defect

ADAMTS3 ACTN4 LTBP1 CREBBP EP300 CASZ1 DNAH11

8.70e-05261577MP:0010402
MousePhenoincreased circulating fibrinogen level

LPA PLG

9.75e-054572MP:0012331
MousePhenoabnormal epicardium development

ITGA4 EP300

9.75e-054572MP:0031590
MousePhenoproctitis

LPA PLG

9.75e-054572MP:0003305
MousePhenopersistent dorsal ophthalmic artery

ADAMTS3 ACTN4

1.62e-045572MP:0013992
MousePhenoabnormal ophthalmic artery morphology

ADAMTS3 ACTN4

2.42e-046572MP:0020489
MousePhenogastric ulcer

LPA PLG

2.42e-046572MP:0003282
MousePhenoincreased acute phase protein level

LPA PLG

3.39e-047572MP:0014499
MousePhenoabnormal pericardium development

ITGA4 EP300

3.39e-047572MP:0031587
MousePhenovenoocclusion

LPA PLG

3.39e-047572MP:0006137
MousePhenoabnormal conjunctival epithelium morphology

LPA PLG

3.39e-047572MP:0004481
MousePhenopeptic ulcer

LPA PLG

3.39e-047572MP:0003301
MousePhenoatrial septal defect

LTBP1 CREBBP EP300 DNAH11

4.49e-0488574MP:0010403
MousePhenoabnormal circulating fibrinogen level

LPA PLG

4.50e-048572MP:0010213
MousePhenodecreased keratinocyte migration

LPA PLG

4.50e-048572MP:0012194
MousePhenoabnormal interventricular septum morphology

ADAMTS3 ACTN4 LTBP1 CREBBP EP300 CASZ1 DNAH11

4.56e-04342577MP:0000281
MousePhenodecreased susceptibility to induced choroidal neovascularization

LPA PLG

7.20e-0410572MP:0003434
MousePhenoabnormal kidney thrombosis

LPA PLG

7.20e-0410572MP:0011507
MousePhenoabnormal vein morphology

ADAMTS3 LPA ACTN4 PLG DNAH11

7.37e-04176575MP:0002725
MousePhenoabnormal neurocranium morphology

ADAMTS3 ACTN4 LTBP1 SIK3 CREBBP TNFRSF11B

7.66e-04269576MP:0000074
MousePhenoabnormal axon guidance

MYCBP2 FEZF2 CRPPA

8.08e-0445573MP:0002961
MousePhenoimpaired somite development

EHMT1 RRN3P2 BCOR EP300

8.44e-04104574MP:0009768
MousePhenosubcutaneous edema

ADAMTS3 ACTN4 CASZ1

8.62e-0446573MP:0013848
MousePhenoabnormal keratinocyte migration

LPA PLG

8.78e-0411572MP:0012192
MousePhenoabnormal interatrial septum morphology

LTBP1 CREBBP EP300 DNAH11

9.38e-04107574MP:0000282
MousePhenointernal hemorrhage

ADAMTS3 LPA ACTN4 PLG ITGA4 CREBBP EP300

9.47e-04387577MP:0001634
MousePhenoabnormal heart septum morphology

ADAMTS3 ACTN4 LTBP1 CREBBP EP300 CASZ1 DNAH11

9.61e-04388577MP:0006113
MousePhenoabnormal craniofacial morphology

ADAMTS3 FEZF2 FEZF1 LRRC32 EHMT1 PLAG1 ACTN4 LTBP1 SIK3 ITGA4 CREBBP EP300 TNFRSF11B DNAH11

9.72e-0413725714MP:0000428
MousePhenocraniofacial phenotype

ADAMTS3 FEZF2 FEZF1 LRRC32 EHMT1 PLAG1 ACTN4 LTBP1 SIK3 ITGA4 CREBBP EP300 TNFRSF11B DNAH11

9.72e-0413725714MP:0005382
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

1.59e-052752IPR014744
DomainHAT_KAT11

CREBBP EP300

1.59e-052752PF08214
DomainKIX

CREBBP EP300

1.59e-052752PS50952
DomainZnF_TAZ

CREBBP EP300

1.59e-052752SM00551
DomainCBP_P300_HAT

CREBBP EP300

1.59e-052752IPR031162
DomainDUF902

CREBBP EP300

1.59e-052752PF06001
Domain-

CREBBP EP300

1.59e-0527521.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

1.59e-052752IPR010303
Domain-

CREBBP EP300

1.59e-0527521.10.1630.10
DomainCreb_binding

CREBBP EP300

1.59e-052752PF09030
Domain-

CREBBP EP300

1.59e-0527521.10.246.20
Domainzf-TAZ

CREBBP EP300

1.59e-052752PF02135
DomainZF_TAZ

CREBBP EP300

1.59e-052752PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

1.59e-052752IPR013178
DomainKAT11

CREBBP EP300

1.59e-052752SM01250
DomainZnf_TAZ

CREBBP EP300

1.59e-052752IPR000197
DomainKIX_dom

CREBBP EP300

1.59e-052752IPR003101
DomainKIX

CREBBP EP300

1.59e-052752PF02172
DomainCBP_P300_HAT

CREBBP EP300

1.59e-052752PS51727
DomainSeptin

SEPTIN5 SEPTIN4 SEPTIN1

1.73e-0513753PF00735
DomainG_SEPTIN_dom

SEPTIN5 SEPTIN4 SEPTIN1

1.73e-0513753IPR030379
DomainG_SEPTIN

SEPTIN5 SEPTIN4 SEPTIN1

1.73e-0513753PS51719
DomainSeptin

SEPTIN5 SEPTIN4 SEPTIN1

2.19e-0514753IPR016491
DomainZnf_C2H2

GTF2H2 ZNF473 ZNF544 FEZF2 FEZF1 ZNF592 ZNF549 PLAG1 ZNF322 ZNF770 CASZ1 ZNF681

8.12e-058057512IPR007087
DomainBromodomain_CS

BRPF3 CREBBP EP300

1.51e-0426753IPR018359
DomainNuc_rcpt_coact

CREBBP EP300

2.36e-046752IPR009110
DomainZINC_FINGER_C2H2_2

ZNF473 ZNF544 FEZF2 FEZF1 ZNF592 ZNF549 PLAG1 ZNF322 ZNF770 CASZ1 ZNF681

2.54e-047757511PS50157
DomainZINC_FINGER_C2H2_1

ZNF473 ZNF544 FEZF2 FEZF1 ZNF592 ZNF549 PLAG1 ZNF322 ZNF770 CASZ1 ZNF681

2.59e-047777511PS00028
DomainKringle-like

LPA PLG LY75

2.84e-0432753IPR013806
DomainZnf_C2H2-like

ZNF473 ZNF544 FEZF2 FEZF1 ZNF592 ZNF549 PLAG1 ZNF322 ZNF770 CASZ1 ZNF681

3.19e-047967511IPR015880
DomainZnF_C2H2

ZNF473 ZNF544 FEZF2 FEZF1 ZNF592 ZNF549 PLAG1 ZNF322 ZNF770 CASZ1 ZNF681

3.62e-048087511SM00355
Domainzf-C2H2

ZNF473 ZNF544 FEZF2 FEZF1 ZNF592 ZNF549 ZNF322 ZNF770 CASZ1 ZNF681

4.35e-046937510PF00096
DomainBROMODOMAIN_1

BRPF3 CREBBP EP300

4.38e-0437753PS00633
DomainBromodomain

BRPF3 CREBBP EP300

4.74e-0438753PF00439
DomainBROMODOMAIN_2

BRPF3 CREBBP EP300

5.94e-0441753PS50014
DomainBROMO

BRPF3 CREBBP EP300

6.38e-0442753SM00297
DomainBromodomain

BRPF3 CREBBP EP300

6.38e-0442753IPR001487
Domain-

BRPF3 CREBBP EP300

6.38e-04427531.20.920.10
Domain-

ZNF473 ZNF544 FEZF2 FEZF1 ZNF549 PLAG1 ZNF322 ZNF770 ZNF681

1.55e-036797593.30.160.60
Domainzf-C2H2_6

ZNF473 FEZF2 FEZF1 ZNF549 ZNF770 ZNF681

1.64e-03314756PF13912
DomainZnf_C2H2/integrase_DNA-bd

ZNF473 ZNF544 FEZF2 FEZF1 ZNF549 PLAG1 ZNF322 ZNF770 ZNF681

1.80e-03694759IPR013087
DomainKringle

LPA PLG

2.08e-0317752IPR000001
DomainKringle_CS

LPA PLG

2.08e-0317752IPR018056
DomainKRINGLE_2

LPA PLG

2.08e-0317752PS50070
DomainKringle

LPA PLG

2.08e-0317752PF00051
DomainKRINGLE_1

LPA PLG

2.08e-0317752PS00021
DomainKR

LPA PLG

2.08e-0317752SM00130
DomainZZ

CREBBP EP300

2.34e-0318752PF00569
DomainZF_ZZ_2

CREBBP EP300

2.34e-0318752PS50135
DomainZF_ZZ_1

CREBBP EP300

2.34e-0318752PS01357
DomainZnf_ZZ

CREBBP EP300

2.60e-0319752IPR000433
DomainZnF_ZZ

CREBBP EP300

2.60e-0319752SM00291
DomainC2H2_Znf_fam

PLAG1 ZNF770

4.15e-0324752IPR027775
PathwayWP_EBOLA_VIRUS_INFECTION_IN_HOST

VPS39 ACTN4 ITGA4 CREBBP EP300

1.43e-04129555M39693
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.48e-045552MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

1.48e-045552M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

1.48e-045552M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

1.48e-045552M27228
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.22e-046552M22062
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

3.10e-047552MM1573
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

4.12e-048552M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

4.12e-048552M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

4.12e-048552M48024
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP1 PLG

4.12e-048552M47850
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

4.12e-048552M46443
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

5.29e-049552M47451
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

6.59e-0410552M27945
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

SCMH1 CREBBP EP300

6.65e-0444553M27295
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

8.04e-0411552MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

8.04e-0411552M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

8.04e-0411552M26924
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

9.62e-0412552M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

9.62e-0412552M27765
PathwayBIOCARTA_FIBRINOLYSIS_PATHWAY

LPA PLG

9.62e-0412552MM1398
PathwayWP_TGFBETA_SIGNALING_PATHWAY

LTBP1 CREBBP EP300

1.15e-0353553MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

LTBP1 CREBBP EP300

1.28e-0355553M39351
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

1.32e-0314552M27808
PathwayBIOCARTA_PLATELETAPP_PATHWAY

LPA PLG

1.32e-0314552MM1458
PathwayBIOCARTA_SET_PATHWAY

GZMH CREBBP

1.32e-0314552MM1403
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.52e-0315552MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.52e-0315552M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.52e-0315552MM1439
PathwayREACTOME_DISSOLUTION_OF_FIBRIN_CLOT

LPA PLG

1.52e-0315552MM15450
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

1.52e-0315552M953
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

LTBP1 CREBBP EP300

1.57e-0359553M39886
PathwayREACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2

BRPF3 LPA ACTN4 PLG

1.64e-03130554MM15455
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

1.73e-0316552M27121
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.73e-0316552M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.73e-0316552MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.73e-0316552M8516
PathwayWP_BDNF_PATHWAY

LPA PLG

1.73e-0316552MM15816
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.73e-0316552M27940
PathwayREACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS

GZMH CTSZ

1.96e-0317552M27104
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.96e-0317552MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

1.96e-0317552M48025
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

BCOR CREBBP EP300

2.07e-0365553M39682
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

BRPF3 GTF2H2 ZNF473 ZNF544 SCMH1 ZNF549 RAD1 EHMT1 ZNF770 ITGA4 CREBBP EP300 ZNF681

2.17e-0313875513M734
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION

EHMT1 EP300

2.20e-0318552MM15342
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

2.20e-0318552M26942
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.45e-0319552M18933
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION

EHMT1 EP300

2.45e-0319552M27639
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

2.45e-0319552M46442
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

BRPF3 GTF2H2 ZNF473 SCMH1 RAD1 EHMT1 ZNF770 EP300 ZNF681

2.69e-03768559MM14851
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

BRPF3 GTF2H2 RAD1 EHMT1 CREBBP EP300

2.69e-03360556M27267
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

2.71e-0320552M27881
PathwayKEGG_ADHERENS_JUNCTION

ACTN4 CREBBP EP300

2.88e-0373553M638
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

2.99e-0321552M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

2.99e-0321552M27485
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

BRPF3 RAD1 EHMT1 EP300

3.25e-03157554MM15226
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

ADAMTS3 LPA LTBP1 PLG ITGA4

3.26e-03258555MM14572
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

3.28e-0322552MM1370
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

3.28e-0322552MM1443
PathwayWP_ESTROGEN_SIGNALING

GTF2H2 CREBBP EP300

3.35e-0377553MM15934
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

BRPF3 RAD1 EHMT1 EP300

3.48e-03160554M27498
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

3.59e-0323552M2821
PathwayWP_BLOOD_CLOTTING_CASCADE

LPA PLG

3.59e-0323552MM15936
Pubmed

Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis.

PLGLA PLG PLGLB1

5.04e-0848231986355
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

GCC2 EHMT1 ZMYM2 SIK3 BCOR CREBBP STAG2 EP300 CASZ1 DNAH11

2.63e-06638821031182584
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NEMP1 BRPF3 TRANK1 ZNF592 VPS39 EHMT1 PDCD11 SIK3 BCOR

4.46e-0652982914621295
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

5.49e-06282227881875
Pubmed

Short-term inhibition of fibrinolytic system restores locomotor function after spinal cord injury in mice.

LPA PLG

5.49e-06282231690812
Pubmed

Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease.

LPA PLG

5.49e-06282230254165
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

5.49e-06282234845315
Pubmed

Fez family transcription factors: controlling neurogenesis and cell fate in the developing mammalian nervous system.

FEZF2 FEZF1

5.49e-06282224913420
Pubmed

Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice.

LPA PLG

5.49e-06282238328826
Pubmed

Reduced transplant arteriosclerosis in plasminogen-deficient mice.

LPA PLG

5.49e-0628229819364
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

5.49e-06282219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

5.49e-06282215860545
Pubmed

Persistent corneal haze after excimer laser photokeratectomy in plasminogen-deficient mice.

LPA PLG

5.49e-06282210634603
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

5.49e-06282229460469
Pubmed

Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis.

LPA PLG

5.49e-06282223943648
Pubmed

In vivo plasminogen deficiency reduces fat accumulation.

LPA PLG

5.49e-06282212083480
Pubmed

Polymorphonuclear leukocyte phagocytic function increases in plasminogen knockout mice.

LPA PLG

5.49e-06282218420257
Pubmed

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction.

LPA PLG

5.49e-0628227705657
Pubmed

Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin.

LPA PLG

5.49e-06282223041318
Pubmed

Plasminogen alleles influence susceptibility to invasive aspergillosis.

LPA PLG

5.49e-06282218566672
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

5.49e-06282224551300
Pubmed

dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.

FEZF2 FEZF1

5.49e-06282220152183
Pubmed

A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis.

LPA PLG

5.49e-06282219752236
Pubmed

Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site.

LPA PLG

5.49e-0628226216475
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

5.49e-06282233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

5.49e-0628229018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

5.49e-06282224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

5.49e-06282230135524
Pubmed

The generation and characterization of mice expressing a plasmin-inactivating active site mutation.

LPA PLG

5.49e-06282220653841
Pubmed

Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis: studies in plasminogen knock-out mice.

LPA PLG

5.49e-06282212428098
Pubmed

Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus.

LPA PLG

5.49e-06282220440070
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

5.49e-06282239287984
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

5.49e-06282216596650
Pubmed

Plasminogen deficiency causes reduced corticospinal axonal plasticity and functional recovery after stroke in mice.

LPA PLG

5.49e-06282224732409
Pubmed

A central role for plasminogen in the inflammatory response to biomaterials.

LPA PLG

5.49e-06282215456492
Pubmed

Plasminogen promotes macrophage phagocytosis in mice.

LPA PLG

5.49e-06282224876560
Pubmed

Plasminogen is a joint-specific positive or negative determinant of arthritis pathogenesis in mice.

LPA PLG

5.49e-06282224574269
Pubmed

Spontaneous development of otitis media in plasminogen-deficient mice.

LPA PLG

5.49e-06282216956791
Pubmed

Staphylococcus aureus manganese transport protein C (MntC) is an extracellular matrix- and plasminogen-binding protein.

LPA PLG

5.49e-06282225409527
Pubmed

The mouse plasminogen locus maps to the recombination breakpoints of the tLub2 and TtOrl partial t haplotypes but is not at the tw73 locus.

LPA PLG

5.49e-0628221543918
Pubmed

Restoration of thrombolytic potential in plasminogen-deficient mice by bolus administration of plasminogen.

LPA PLG

5.49e-0628228704243
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

5.49e-06282229217654
Pubmed

BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion.

BCOR CREBBP

5.49e-06282238637838
Pubmed

Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: role of plasmin-activated signals.

LPA PLG

5.49e-06282217267741
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

5.49e-06282220717166
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

5.49e-06282210049825
Pubmed

Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.

LPA PLG

5.49e-06282223702659
Pubmed

Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells.

LPA PLG

5.49e-06282229990619
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

5.49e-06282227380996
Pubmed

Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector.

LPA PLG

5.49e-06282217293777
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

5.49e-06282229170789
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

5.49e-06282225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

5.49e-06282211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

5.49e-06282221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

5.49e-06282212646247
Pubmed

An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division.

FEZF2 FEZF1

5.49e-06282228245922
Pubmed

Plasminogen plays a crucial role in bone repair.

LPA PLG

5.49e-06282223456978
Pubmed

Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction.

LPA PLG

5.49e-06282210854210
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

5.49e-06282232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

5.49e-06282219822209
Pubmed

Gender affects skin wound healing in plasminogen deficient mice.

LPA PLG

5.49e-06282223527289
Pubmed

Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation.

LPA PLG

5.49e-06282222079981
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

5.49e-06282224522976
Pubmed

Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice.

LPA PLG

5.49e-0628229490683
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

5.49e-06282211867645
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

5.49e-06282221847097
Pubmed

Kringle 5 of human plasminogen suppresses hepatocellular carcinoma growth both in grafted and xenografted mice by anti-angiogenic activity.

LPA PLG

5.49e-06282216481742
Pubmed

Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen: a novel mechanism for lipoprotein(a)-mediated inhibition of plasminogen activation.

LPA PLG

5.49e-06282218983515
Pubmed

Plasminogen Regulates Fracture Repair by Promoting the Functions of Periosteal Mesenchymal Progenitors.

LPA PLG

5.49e-06282234378815
Pubmed

Plasmin generation plays different roles in the formation and removal of arterial and venous thrombus in mice.

LPA PLG

5.49e-06282211848464
Pubmed

Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice.

LPA PLG

5.49e-0628227586361
Pubmed

Plasminogen/plasmin modulates bone metabolism by regulating the osteoblast and osteoclast function.

LPA PLG

5.49e-06282221239499
Pubmed

Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice.

LPA PLG

5.49e-06282210642175
Pubmed

Plasminogen mRNA induction in the mouse brain after kainate excitation: codistribution with plasminogen activator inhibitor-2 (PAI-2) mRNA.

LPA PLG

5.49e-06282212225871
Pubmed

Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice.

LPA PLG

5.49e-0628229770530
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

5.49e-06282211963968
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

5.49e-06282234813504
Pubmed

Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex.

FEZF2 FEZF1

5.49e-06282216314561
Pubmed

Plasminogen activation is required for the development of radiation-induced dermatitis.

LPA PLG

5.49e-06282230323258
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

5.49e-0628229528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

5.49e-06282212696060
Pubmed

Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression.

LPA PLG

5.49e-06282237971174
Pubmed

The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis.

LPA PLG

5.49e-0628229884337
Pubmed

Colonic Lesions, Cytokine Profiles, and Gut Microbiota in Plasminogen-Deficient Mice.

LPA PLG

5.49e-06282226473342
Pubmed

Nonfibrinolytic functions of plasminogen.

LPA PLG

5.49e-06282210816371
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

5.49e-06282220301699
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

5.49e-06282236109165
Pubmed

Plasminogen is a critical regulator of cutaneous wound healing.

LPA PLG

5.49e-06282226791370
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

5.49e-06282224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

5.49e-06282237816914
Pubmed

Selection of mutant µplasmin for amyloid-β cleavage in vivo.

LPA PLG

5.49e-06282232694536
Pubmed

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma.

LPA PLG

5.49e-0628227525077
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

5.49e-06282212242694
Pubmed

Contrasting roles of plasminogen deficiency in different rheumatoid arthritis models.

LPA PLG

5.49e-06282216052596
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

5.49e-06282211438528
Pubmed

Functional corpora lutea are formed in matrix metalloproteinase inhibitor-treated plasminogen-deficient mice.

LPA PLG

5.49e-06282217122079
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

5.49e-06282210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

5.49e-06282231182547
Pubmed

Role of plasminogen in propagation of scrapie.

LPA PLG

5.49e-06282216103174
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

5.49e-06282235502657
CytobandEnsembl 112 genes in cytogenetic band chr6q26

LPA PLG

3.72e-0416822chr6q26
CytobandEnsembl 112 genes in cytogenetic band chr8q24

CYC1 IQANK1 MTBP SNTB1 TNFRSF11B

4.50e-04355825chr8q24
Cytoband6q26

LPA PLG

4.73e-04188226q26
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF473 ZNF544 FEZF2 FEZF1 ZNF592 ZNF549 PLAG1 ZNF322 ZNF770 CASZ1 ZNF681

4.90e-06718521128
GeneFamilySeptins

SEPTIN5 SEPTIN4 SEPTIN1

6.29e-0613523732
GeneFamilyDyneins, axonemal

DNAH17 DNAH11

1.07e-0317522536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.07e-0317522486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.21e-031852291
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

PDCD11 LY75

9.45e-0351522870
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 GCC2 DOCK10 ITGA4 STAG2 EP300

1.09e-06182826f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 GCC2 DOCK10 ITGA4 STAG2 EP300

1.17e-061848261154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 GCC2 DOCK10 ITGA4 STAG2 EP300

1.20e-061858267adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TRANK1 GCC2 ZNF322 ZNF770 CREBBP EP300

1.24e-0618682603db813598b67b1e08f759758a1c2023396921fa
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEMP1 CACUL1 ZNF592 BCOR TNFRSF11B

1.03e-05156825abea3c183d32062b009a79a2bdf861021989c7ef
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEFF1 MYCBP2 ITGA4 CREBBP ALPK2

1.24e-0516282593bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

PLGLA LPA PLG PLGLB1 C9

1.75e-05174825452932f08cf53e5949672a025d78cecb874aa4b0
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

PLGLA LPA PLG PLGLB1 C9

1.80e-051758257f74961436f88c0e380819095e6104489914d765
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

PLGLA LPA PLG PLGLB1 C9

1.80e-05175825bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 SNTB1 ALPK2 TNFRSF11B DNAH11

2.17e-051828255e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

OR5H6 DOCK10 ITGA4 LY75 ALPK2

2.23e-05183825e01dacb08a9c36cf09c0b6764ce032a7232d4cdc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 SNTB1 ALPK2 TNFRSF11B DNAH11

2.41e-051868255c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC6A1 SEPTIN5 MARK1 LTBP1 TNFRSF11B

2.41e-051868254780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLC6A1 SEPTIN4 MARK1 LRRC32 ITGA4

2.48e-05187825406ff9327d3109fe1e251629c4c617b00a573dc2
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

KLHL28 GCC2 ZNF770 BCOR STAG2

2.88e-05193825abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLC6A1 SEPTIN4 LRRC32 DOCK10 ITGA4

3.25e-0519882572aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK10 ITGA4 LY75 ALPK2 TNFRSF11B

3.33e-05199825f4ab29f99ce45a3044d2e9f356dc24d3c5e7121f
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC6A1 SEPTIN5 MARK1 LTBP1 TNFRSF11B

3.41e-052008259169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_only / Treatment groups by lineage, cell group, cell type

SLC6A1 SEPTIN5 MARK1 LTBP1 TNFRSF11B

3.41e-052008257c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KCNB1 SEPTIN4 MARK1 PTPN21

1.34e-04141824dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

NDNF PTPN21 C9 ALPK2

1.34e-041418247671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNB1 ACTN4 DBT SNTB1

1.53e-04146824447c05414eda71681a0c07baba900f88ed6165ed
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC6A1 NDNF DOCK10 LTBP1

1.61e-041488245e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNB1 ADAMTS3 ACRBP ALPK2

1.65e-04149824cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNB1 ADAMTS3 ACRBP ALPK2

1.65e-0414982424a7538b54b2a5291503c7493fefed4e45e8d710
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRPF3 GZMH SEPTIN1 BCOR

1.78e-041528240fda8980b10ce16179dea92301db74d728f41794
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC6A1 NDNF DOCK10 LTBP1

1.78e-041528248ff5a178a8f3550d89a003c0858820aab3773386
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NDNF PLAG1 MTBP SIK3

1.97e-041568244877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NDNF PLAG1 MTBP SIK3

1.97e-041568241d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS3 DOCK10 ITGA4 LY75

2.07e-0415882490ca742739a208d457db087655ba3d1c18a9da57
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS3 DOCK10 ITGA4 LY75

2.17e-041608248dae9b0cf90a09acb196223f45a14680102630b2
ToppCellcellseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-ILC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GZMH SEPTIN1 CEP76 ITGA4

2.28e-04162824553f91eaba72bcffb733ede45418bbee39c653ab
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TMEFF1 SLC6A1 NDNF DOCK10

2.33e-041638248d17f44faf0549fe71a9a45f811f50d767275414
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Striatum / BrainAtlas - Mouse McCarroll V32

LRRC32 ACTN4 LTBP1 ITGA4

2.39e-04164824e24b06a14565f7798ac50c2fe3f34d4547b9000e
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDNF DOCK10 ITGA4 ALPK2

2.44e-041658248a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellCOVID-19_Mild-PLT_0|COVID-19_Mild / Disease Group and Platelet Clusters

SEPTIN5 P3H1 PRR11 PLG

2.44e-04165824083a14d3b0162cee4e79f7398b8fb739582b39ff
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC6A1 NEMP1 ZNF322 BCOR

2.50e-04166824c8fd241088de27c6e741a5dfee3cd770183b6bcb
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 GZMH LRRC32 SEPTIN1

2.56e-04167824eed22d1a17aab84dacb1a488528bae9389644cb9
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A1 SEPTIN4 LRRC32 DNAH11

2.74e-04170824d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD1 SEPTIN1 DOCK10 LY75

2.74e-041708243ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRPF3 SEPTIN1 LY75 USP16

2.80e-04171824f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

EVA1C ADAMTS3 ALPK2 TNFRSF11B

2.86e-0417282436a96714a0eb6ac438648135336c9791881ddadb
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC32 ACTN4 ITGA4 SNTB1

2.92e-0417382451328a60ffaf34fa0f7df6084d348b5efc9917f5
ToppCellGlobus_pallidus-Endothelial-MURAL|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC32 ACTN4 ITGA4 SNTB1

2.92e-04173824b77cd5dbda3a206922f20224f4e10a3bf712f7db
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC6A1 MARK1 LRRC32 ITGA4

2.99e-04174824015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIK3 EP300 SNTB1 CASZ1

3.05e-04175824dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellmetastatic_Brain-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

ITGA4 LY75 TNFRSF11B DNAH11

3.12e-041768249c1f255de3082b3da4bef2a9bdff710cfd48261f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A1 LTBP1 ITGA4 DNAH11

3.19e-041778244943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A1 LTBP1 ITGA4 DNAH11

3.19e-041778243f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 SEPTIN1 DOCK10 ITGA4

3.26e-04178824d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 SEPTIN1 DOCK10 ITGA4

3.26e-04178824b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A1 NDNF LRRC32 DOCK10

3.26e-04178824e86ed30652c2de70f16430f04b78789b87df4af2
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 SEPTIN1 DOCK10 ITGA4

3.26e-041788240f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FCF1 DNAJC10 ZNF473 PRR11

3.33e-04179824af03705a783e77f75c44fdfa793cfdccbf9dd91c
ToppCellTCGA-Liver-Solid_Tissue_Normal-Liver|TCGA-Liver / Sample_Type by Project: Shred V9

PLGLA LPA PLGLB1 C9

3.33e-041798240e22e840f43ca81a7543dcf33ec17a741cdf7f37
ToppCellTCGA-Liver-Solid_Tissue_Normal-Liver-Liver_normal_tissue|TCGA-Liver / Sample_Type by Project: Shred V9

PLGLA LPA PLGLB1 C9

3.33e-0417982417ba1eedb6ebf039d3b11d099351d0ac6363c8d1
ToppCellTCGA-Liver-Solid_Tissue_Normal|TCGA-Liver / Sample_Type by Project: Shred V9

PLGLA LPA PLGLB1 C9

3.33e-041798247046f0a426e45fe1b41a25721ee1e33f6fc7f9e3
ToppCellTCGA-Liver-Solid_Tissue_Normal-Liver-Liver_normal_tissue-2|TCGA-Liver / Sample_Type by Project: Shred V9

PLGLA LPA PLGLB1 C9

3.33e-04179824a20bb3ace5be10c5aef330e9268c0ba55f8fee23
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C SIK3 SNTB1 DNAH11

3.40e-04180824cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A1 NDNF LRRC32 DOCK10

3.40e-04180824392bc71a69653ba12de31bed4e9357f181094641
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A1 NDNF LRRC32 DOCK10

3.47e-041818248fd64404e57c22c204d835fc5626f73554257b19
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEFF1 ADAMTS3 CRPPA LY75

3.47e-041818247af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 SNTB1 ALPK2 TNFRSF11B

3.47e-041818246956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 IQANK1 ZNF473 DNAH11

3.47e-04181824dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 GCC2 LY75 STAG2

3.54e-04182824e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellremission-Platelet|remission / disease stage, cell group and cell class

FAM187B ACRBP LRRC32 LTBP1

3.54e-0418282465e2798aacd670cbc3a8c8e9d1a2f7768513bb70
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 GCC2 LY75 STAG2

3.54e-041828241710eab3037a87609d21838be2d2d29c3bc36651
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)|Cerebellum / BrainAtlas - Mouse McCarroll V32

P3H1 LRRC32 ACTN4 ITGA4

3.54e-04182824da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCellCerebellum-Endothelial-MURAL|Cerebellum / BrainAtlas - Mouse McCarroll V32

P3H1 LRRC32 ACTN4 ITGA4

3.54e-04182824b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM187B ZNF473 SEPTIN4 BCOR

3.62e-04183824dc9602bed3136db91faeffef177006246dc92743
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALCR SNTB1 CASZ1 TNFRSF11B

3.69e-04184824d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early|lymph-node_spleen / Manually curated celltypes from each tissue

TMEFF1 ACRBP SEPTIN4 LTBP1

3.69e-0418482410607d7d92edcbb92d992900086b90b307421cc3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACRBP LRRC32 LTBP1 DNAH11

3.77e-04185824c985a4b184d382a79aaff07f81c0efede2c2d493
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACRBP LRRC32 LTBP1 DNAH11

3.77e-04185824d0d0e000ebe1fc35a987930ceaf7e3369e0c694c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACRBP LRRC32 LTBP1 DNAH11

3.77e-041858240ca99fcbd30c454bcdc2aa5265a0e4dba25666ea
ToppCellfacs-Kidney-nan-18m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEMP1 SEPTIN1 DOCK10 ITGA4

3.77e-04185824a3b937163346d729115e6335336e33d3e71fccb0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACRBP LRRC32 LTBP1 DNAH11

3.77e-041858240f722ffcc3e78d5c6b1b79d31d00929801a993f1
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAJC10 GZMH SEPTIN1 ITGA4

3.85e-04186824bbcd9062c0f6f65ca6f3cb101b6fa72ddd1e14fe
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Platelet|World / Lineage, cell class and subclass

SEPTIN5 ACRBP SEPTIN4 LTBP1

3.85e-0418682427807334e7241c8a9aeaf6403f0fd0b001fbc0d1
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A1 SEPTIN4 LRRC32 DNAH11

3.85e-041868246568358812f0ca4e0161a1a1b29682fbced35c79
ToppCellNasal_Brush-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

P3H1 PDCD11 SNTB1 CASZ1

3.85e-04186824f5aa91dbef29f7efa2b9a728c6539d7541340cd4
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(2)_5-FU / Stress and Cell class

NDNF MYCBP2 LTBP1 CTSZ

3.92e-041878246bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A1 LTBP1 ITGA4 DNAH11

3.92e-04187824ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH ACTN4 ITGA4 CASZ1

3.92e-04187824d17352f769c3c66601b65d060626eecff41b0482
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A1 LTBP1 ITGA4 DNAH11

3.92e-04187824530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellE17.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN5 MARK1 ITGA4 TNFRSF11B

3.92e-041878240dee138738b65531ff134a125b92234b5d0a653c
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ACTN4 LTBP1 CASZ1 ALPK2

4.00e-041888246d249fe92d51a19da19ec14bb2262d394255d577
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EVA1C KCNB1 LRRC32 LTBP1

4.00e-041888245eb107122064f0a99dfd445cc87d3766f7257216
ToppCell11.5-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

SEPTIN5 SEPTIN4 LRRC32 ITGA4

4.00e-04188824916971d8660fd20f616346953874e89d2cd13e88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRANK1 ADAMTS3 LTBP1 ADGRG4

4.00e-04188824ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell15-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

SLC6A1 SEPTIN4 LRRC32 ITGA4

4.00e-041888244963382e54aac06bf5047c7d725393db70667ee7
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Trm_Th1/Th17|Lung / Manually curated celltypes from each tissue

GZMH SEPTIN1 SIK3 ITGA4

4.09e-04189824f43960506ed3e699e910ec7711c1113e2e9b80d1
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

SEPTIN4 LRRC32 ITGA4 DNAH11

4.09e-041898249c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 ITGA4 LY75 TNFRSF11B

4.17e-041908242ff4b50b864a35f22c558d7d585cd2b54612b50c
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRANK1 GZMH SEPTIN1 ITGA4

4.17e-0419082455df73c8b696967a925b1772631f6900eff0fa30
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EVA1C KCNB1 LRRC32 LTBP1

4.17e-04190824e1b721bb74561fe51c53328a0394c9954e489049
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

ACTN4 DDX60L SIK3 ALPK2

4.17e-0419082493c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRANK1 ADAMTS3 LTBP1 ADGRG4

4.17e-04190824efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells|World / Lineage, cell class and subclass

SEPTIN5 ACRBP SEPTIN4 LTBP1

4.17e-0419082472b61a12ccea506272ce9cef9051aa2612e6ce57
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRANK1 GZMH SEPTIN1 ITGA4

4.17e-04190824494fbab37305a7f92cddec75b291d42282555f5f
DrugFibrin

PLGLA PLG PLGLB1

3.72e-069823CID000439199
Drugaminopropylsilane

FEZF2 ITGA4 C9

9.68e-0612823CID006337902
DiseaseMenke-Hennekam syndrome

CREBBP EP300

6.37e-062752cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

6.37e-062752DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

6.37e-062752cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

6.37e-062752C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

6.37e-062752180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

6.37e-062752cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

6.37e-062752DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

6.37e-062752C0035934
Diseasechronic kidney disease, APOL1 risk genotype carrier status

LPA PLG

6.34e-055752EFO_0003884, EFO_0009324
Diseaseplasma plasminogen measurement

LPA PLG

6.34e-055752EFO_0006309
Diseasechylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

LPA SIK3 PLG

8.92e-0534753EFO_0008317, EFO_0008596, EFO_0020947
Diseaseretinitis pigmentosa

DNAJC10 ITGA4

9.50e-056752MONDO_0019200
Diseaseangiostatin measurement

LPA PLG

9.50e-056752EFO_0008024
Diseasecholesteryl esters to total lipids in medium LDL percentage

LPA SIK3 PLG

1.15e-0437753EFO_0022252
Diseaselipoprotein A measurement, apolipoprotein A 1 measurement

LPA PLG

1.33e-047752EFO_0004614, EFO_0006925
Diseaseplatelet measurement

FAM187B SEPTIN5 DOCK10 ACTN4 LY75 CTSZ

1.53e-04315756EFO_0005036
DiseaseCarcinoma, Transitional Cell

CREBBP STAG2 EP300

1.57e-0441753C0007138
Diseasecholesteryl esters to total lipids in small LDL percentage

LPA SIK3 PLG

1.69e-0442753EFO_0022255
Diseasefree cholesterol to total lipids in very small VLDL percentage

LPA SIK3 PLG

1.81e-0443753EFO_0022290
Diseasemean platelet volume

FAM187B TRANK1 GCC2 DOCK10 ACTN4 LTBP1 SIK3 BCOR LY75 CTSZ

2.52e-0410207510EFO_0004584
Diseasepolyunsaturated fatty acids to total fatty acids percentage

LPA SIK3 PLG

2.84e-0450753EFO_0022303
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

LPA SIK3 PLG

3.01e-0451753EFO_0022302
Diseasecholesterol to total lipids in small HDL percentage

LPA SIK3 PLG

3.01e-0451753EFO_0022240
Diseasetriglycerides in HDL measurement

LPA SIK3 PLG

3.37e-0453753EFO_0022317
Diseasefree cholesterol to total lipids in small LDL percentage

LPA SIK3 PLG

3.37e-0453753EFO_0022286
Diseasepolyunsaturated fatty acid measurement

LPA SIK3 PLG DNAH11

3.53e-04131754EFO_0010733
Diseasetriglycerides in medium HDL measurement

LPA SIK3 PLG

3.56e-0454753EFO_0022321
Diseasetriglycerides in LDL measurement

LPA SIK3 PLG

3.97e-0456753EFO_0022320
Diseasetriglycerides to total lipids in medium HDL percentage

LPA SIK3 PLG

3.97e-0456753EFO_0022333
Diseasecholesterol to total lipids in large LDL percentage

LPA SIK3 PLG

3.97e-0456753EFO_0022235
Diseasecholesteryl esters to total lipids in medium HDL percentage

LPA SIK3 PLG

3.97e-0456753EFO_0022251
Diseasetriglycerides to total lipids in small LDL percentage

LPA SIK3 PLG

4.63e-0459753EFO_0022337
Diseasesexual dimorphism measurement

BRPF3 TRANK1 ADAMTS3 ZNF592 SCMH1 LPA PLAG1 ZNF322 LTBP1 SIK3

4.78e-0411067510EFO_0021796
Diseasetriglycerides to total lipids in large HDL percentage

LPA SIK3 PLG

4.86e-0460753EFO_0022330
Diseasecholesterol to total lipids in medium HDL percentage

LPA SIK3 PLG

4.86e-0460753EFO_0022237
DiseaseHypercalcemia

CALCR TNFRSF11B

4.88e-0413752C0020437
DiseaseMilk-Alkali Syndrome

CALCR TNFRSF11B

4.88e-0413752C0026141
Diseasetriglycerides in small VLDL measurement

LPA SIK3 PLG

5.11e-0461753EFO_0022145
Diseasefree cholesterol in HDL measurement

LPA SIK3 PLG

5.11e-0461753EFO_0022264
Diseasetriglycerides in medium LDL measurement

LPA SIK3 PLG

5.36e-0462753EFO_0022322
Diseasetriglycerides to total lipids in very large HDL percentage

LPA SIK3 PLG

5.36e-0462753EFO_0022339
Diseasetriglycerides in small HDL measurement

LPA SIK3 PLG

5.36e-0462753EFO_0022158
Diseasephospholipids in large VLDL measurement

LPA SIK3 PLG

5.36e-0462753EFO_0022169
Diseasetriglycerides to total lipids in medium VLDL percentage

LPA SIK3 PLG

5.61e-0463753EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

LPA SIK3 PLG

5.61e-0463753EFO_0022239
Diseasefree cholesterol to total lipids in medium LDL percentage

LPA SIK3 PLG

5.61e-0463753EFO_0022283
Diseasecholesteryl esters to total lipids in medium VLDL percentage

LPA SIK3 PLG

5.88e-0464753EFO_0022253
Diseasetriglycerides in small LDL measurement

LPA SIK3 PLG

6.15e-0465753EFO_0022323
Diseasecholesterol to total lipids in very small VLDL percentage

LPA SIK3 PLG

6.72e-0467753EFO_0022245
Diseasetriglycerides to phosphoglycerides ratio

LPA SIK3 PLG

7.02e-0468753EFO_0022327
Diseasefree cholesterol in large VLDL measurement

LPA SIK3 PLG

7.02e-0468753EFO_0022265
Diseasetriglycerides to total lipids in very small VLDL percentage

LPA SIK3 PLG

7.33e-0469753EFO_0022341
Diseasediabetic retinopathy (implicated_via_orthology)

ITGA4 EP300

7.48e-0416752DOID:8947 (implicated_via_orthology)
Diseasetriglycerides to total lipids in small HDL percentage

LPA SIK3 PLG

8.29e-0472753EFO_0022336
Diseasefree cholesterol to total lipids in large LDL percentage

LPA SIK3 PLG

8.98e-0474753EFO_0022280
Diseasefree cholesterol to total lipids in small VLDL percentage

LPA SIK3 PLG

9.34e-0475753EFO_0022287
DiseaseLeukemia, Myelocytic, Acute

BCOR CREBBP EP300 CTSZ

1.00e-03173754C0023467
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

LPA SIK3 PLG

1.05e-0378753EFO_0022187
Diseasecerebral infarction (is_marker_for)

LPA TNFRSF11B

1.06e-0319752DOID:3526 (is_marker_for)
Diseasecholesterol in large HDL measurement

LPA SIK3 PLG

1.13e-0380753EFO_0021900
DiseaseDeep Vein Thrombosis

LPA PLG

1.30e-0321752C0149871
DiseaseVenous Thrombosis

LPA PLG

1.30e-0321752C0042487
Diseaseomega-6 polyunsaturated fatty acid measurement

LPA SIK3 PLG DNAH11

1.62e-03197754EFO_0005680
DiseaseCoronary heart disease

LPA DNAH11

1.70e-0324752C0010068
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement

LPA SIK3 PLG

1.85e-0395753EFO_0004529, EFO_0008317, EFO_0008596
Diseasechylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement

LPA SIK3 PLG

1.90e-0396753EFO_0004530, EFO_0008317, EFO_0008596
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

LPA PLG DNAH11

2.08e-0399753EFO_0004611, EFO_0007878
DiseaseAdenoid Cystic Carcinoma

BCOR CREBBP EP300

2.14e-03100753C0010606
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

LPA SIK3 PLG DNAH11

2.22e-03215754EFO_0008317, EFO_0008591
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

LPA PLG DNAH11

2.26e-03102753EFO_0004329, EFO_0004611
Diseaseantipsychotic drug use measurement

ZNF473 SNTB1

2.48e-0329752EFO_0007792
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

LPA SIK3 PLG

2.52e-03106753EFO_0008317, EFO_0008596

Protein segments in the cluster

PeptideGeneStartEntry
CRAFQYHSKEQQCVI

PLGLB1

61

Q02325
NRYHFCEKCFNEIQG

EP300

1196

Q09472
QSQDRFVYTCNECKH

EP300

1661

Q09472
GTCNEFKECHAIRNY

CTSZ

171

Q9UBR2
VKETNVNYTICQCDH

ADGRG4

2706

Q8IZF6
FIDQFKALHQCNKYC

ALPK2

2111

Q86TB3
YCFCNNEVQTTVKRQ

CALCR

391

P30988
CKYNQVNSHFHCIRE

CASZ1

1291

Q86V15
CSNHVYYAKRVLCSQ

ACRBP

111

Q8NEB7
VQKDCQCERLFHGNY

GZMH

166

P20718
YDSHNVNTRCQKICD

ACTN4

486

O43707
QNRYHFCEKCFTEIQ

CREBBP

1231

Q92793
QKHCFVNICDAQFQY

DNAH11

1841

Q96DT5
KVNCYTAFHVTCAQR

BRPF3

341

Q9ULD4
QVCSTFTLCLHYRNQ

CEP76

131

Q8TAP6
RRGFQVYKQVCASCH

CYC1

111

P08574
YCLENKICDVNHRDN

BCOR

1481

Q6W2J9
EQIYSCVYKCVCQQH

CACUL1

161

Q86Y37
EAFHCNQTQVNRYKI

RAD1

211

O60671
HYIQVLNCKQNCVTE

P3H1

271

Q32P28
HLQQIILDQCYNFVC

CRPPA

326

A4D126
KLICVRYFQTCGNVH

DBT

16

P11182
FTRDYCHNVLNCQVL

DDX60L

826

Q5H9U9
YKRVNNTFCQDINEC

LTBP1

616

Q14766
QVCEKRASQQFCYTN

NEMP1

56

O14524
FQNCCYNFIITKNRH

LY75

1251

O60449
YCVVINKEHNFKSLC

NDNF

211

Q8TB73
CRAFQYHSKEQQCVI

PLGLA

61

Q15195
LCVARHKFYRLNQCN

PTPN21

296

Q16825
RLTFCNSNIIQHFYC

OR5H6

181

Q8NGV6
AACCCVRRQKFNQQY

LRRC32

646

Q14392
CYGKQRCKIIVNNHH

EVA1C

226

P58658
EYQLCNTEECQKHFE

ADAMTS3

596

O15072
EIYLESCCQARYHQK

KCNB1

126

Q14721
ATKYICQNFEAVCQT

KLHL28

156

Q9NXS3
QCKNQCHENEIRIAY

DEFB110

41

Q30KQ9
LCQYKFDFLQEVCQH

DOCK10

1091

Q96BY6
RHCFANICDAQIQYS

DNAH17

1796

Q9UFH2
ADDCLVQRVTQHKCY

FCF1

141

Q9Y324
LNKQFCYTVEQHNRE

GCC2

411

Q8IWJ2
LFHLYAACKSINQEC

GJE1

91

A6NN92
LVIENEVCNHYKYIC

LPA

1961

P08519
AKFRQIVSAVQYCHQ

MARK1

161

Q9P0L2
ECHFENYQRVCALEQ

ITGA4

851

P13612
CHVQCTNNTQLRVDY

FAM187B

201

Q17R55
CQQYHSFCAQENVQR

DNAJC10

616

Q8IXB1
RADHQACINFYCTQF

CFAP47

2716

Q6ZTR5
NIDRNITHLQYCVCI

EHMT1

1051

Q9H9B1
YINEFSVRKCHTCQN

C9

501

P02748
CTICNKAFHQVYNLT

FEZF2

391

Q8TBJ5
NHCEINCQKIAEYLS

MTBP

206

Q96DY7
ELKDQHVYVCAVCQN

GTF2H2C;

351

Q6P1K8
CTYKNQECRLTIHYE

SNTB1

446

Q13884
SFHNNVYRDSIIVCC

SLC6A1

311

P30531
KNIQDNRVHCCLYFI

SEPTIN4

246

O43236
KNIQDNRVHCCLYFI

SEPTIN5

146

Q99719
INQLFRNEKHCRNCF

PKDREJ

871

Q9NTG1
QFKCNICNKAFHQVY

FEZF1

371

A0PJY2
QIVTAVYFCHCRNIV

SIK3

171

Q9Y2K2
SAFNIYCNVRHCVLE

MYCBP2

146

O75592
QQCHKELQQAYCELS

IQANK1

326

A8MXQ7
CRAFQYHSKEQQCVI

PLG

61

P00747
QAVQACIDCAYHQKT

SCMH1

396

Q96GD3
VHTGRKDFLCQYCAQ

PLAG1

206

Q6DJT9
RKNIQDSRVHCCLYF

SEPTIN1

131

Q8WYJ6
YFSNQAVRACILCVH

PDCD11

321

Q14690
QYVKQECNRTHNRVC

TNFRSF11B

91

O00300
QRTHNAEKPYVCNIC

ZNF549

266

Q6P9A3
CSIQHCLYQFTRNEK

USP16

631

Q9Y5T5
RVFCQICQHYLTNVN

STAG2

766

Q8N3U4
ELKDQHVYVCAVCQN

GTF2H2

351

Q13888
LCRSAYFQTHVKENC

ZNF592

776

Q92610
HIYQCLECKQNFCEN

ZNF322

41

Q6U7Q0
NNSKICTIECYVHNL

RRN3P2

191

A6NIE6
HQEKNDVFLYRCSVC

ZNF770

616

Q6IQ21
CDQHCLLRFYCQQNE

ZMYM2

791

Q9UBW7
HQCARAFCQSIYLSK

ZNF544

216

Q6NX49
TQHKIICTRVNFYKC

ZNF681

186

Q96N22
KCACQFQCHTNYIPV

TMEFF1

96

Q8IYR6
SQCYKDAFRCFEQIQ

TRANK1

1806

O15050
RICHRELYSVKQQFC

PRR11

106

Q96HE9
YRVEAIQCQTCSKSH

ZAR1L

266

A6NP61
SRFHNCLIQLYCEKV

VPS39

616

Q96JC1
HTQETLYQCQRCQKA

ZNF473

836

Q8WTR7