Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	RELN IGF1R FBN1 PDGFRB PIK3CG TBCK LRRK2 CD40 TBC1D2B BCL2L2 LTF POLG2 STAT3	2.24e-05	1028	67	13	GO:0043085
GeneOntologyBiologicalProcess	positive regulation of transferase activity	RELN IGF1R FBN1 PDGFRB PIK3CG LRRK2 CD40 LTF POLG2	2.82e-05	490	67	9	GO:0051347
GeneOntologyBiologicalProcess	positive regulation of molecular function	RELN MFNG IGF1R FBN1 PDGFRB PIK3CG PDZK1 TBCK LRRK2 CD40 TBC1D2B BCL2L2 LTF POLG2 STAT3	4.27e-05	1430	67	15	GO:0044093
GeneOntologyBiologicalProcess	positive regulation of kinase activity	RELN IGF1R FBN1 PDGFRB PIK3CG LRRK2 CD40 LTF	4.89e-05	405	67	8	GO:0033674
GeneOntologyBiologicalProcess	positive regulation of phosphate metabolic process	RELN IGF1R FBN1 NSMF CD244 PDGFRB PIK3CG LRRK2 CD40 LTF STAT3	1.14e-04	879	67	11	GO:0045937
GeneOntologyBiologicalProcess	positive regulation of phosphorus metabolic process	RELN IGF1R FBN1 NSMF CD244 PDGFRB PIK3CG LRRK2 CD40 LTF STAT3	1.14e-04	879	67	11	GO:0010562
GeneOntologyBiologicalProcess	positive regulation of protein kinase activity	RELN FBN1 PDGFRB PIK3CG LRRK2 CD40 LTF	1.38e-04	350	67	7	GO:0045860
GeneOntologyBiologicalProcess	negative regulation of osteoclast development	FBN1 LTF	1.55e-04	6	67	2	GO:2001205
Domain	Quino_amine_DH_bsu	NBAS VPS8 LRRK2	6.47e-05	22	67	3	IPR011044
Domain	PINIT	PIAS3 PIAS2	7.57e-05	4	67	2	IPR023321
Domain	PINIT	PIAS3 PIAS2	7.57e-05	4	67	2	PS51466
Domain	PINIT	PIAS3 PIAS2	7.57e-05	4	67	2	PF14324
Domain	zf-MIZ	PIAS3 PIAS2	2.63e-04	7	67	2	PF02891
Domain	ZF_SP_RING	PIAS3 PIAS2	2.63e-04	7	67	2	PS51044
Domain	Znf_MIZ	PIAS3 PIAS2	3.50e-04	8	67	2	IPR004181
Domain	Peptidase_M12B_N	ADAMTS9 ADAM20 ADAM30	3.68e-04	39	67	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS9 ADAM20 ADAM30	3.68e-04	39	67	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS9 ADAM20 ADAM30	3.96e-04	40	67	3	PS00427
Domain	Reprolysin	ADAMTS9 ADAM20 ADAM30	3.96e-04	40	67	3	PF01421
Domain	ADAM_MEPRO	ADAMTS9 ADAM20 ADAM30	3.96e-04	40	67	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS9 ADAM20 ADAM30	3.96e-04	40	67	3	PS50214
Domain	Peptidase_M12B	ADAMTS9 ADAM20 ADAM30	3.96e-04	40	67	3	IPR001590
Domain	CYSTEINE_SWITCH	ADAMTS9 ADAM20 ADAM30	4.27e-04	41	67	3	PS00546
Domain	Disintegrin_dom	ADAMTS9 ADAM20 ADAM30	4.27e-04	41	67	3	IPR001762
Domain	Pept_M10_metallopeptidase	ADAMTS9 ADAM20 ADAM30	4.91e-04	43	67	3	IPR001818
Domain	Kinase-like_dom	IGF1R PDGFRB PIK3CG TBCK LRRK2 PAN3 STK35 NEK9	6.92e-04	542	67	8	IPR011009
Domain	TBC	USP6 TBCK TBC1D2B	7.22e-04	49	67	3	SM00164
Domain	RabGAP-TBC	USP6 TBCK TBC1D2B	9.09e-04	53	67	3	PF00566
Domain	TBC_RABGAP	USP6 TBCK TBC1D2B	1.01e-03	55	67	3	PS50086
Domain	Rab-GTPase-TBC_dom	USP6 TBCK TBC1D2B	1.01e-03	55	67	3	IPR000195
Domain	Disintegrin_CS	ADAM20 ADAM30	1.47e-03	16	67	2	IPR018358
Domain	Prot_kinase_dom	IGF1R PDGFRB TBCK LRRK2 PAN3 STK35 NEK9	1.81e-03	489	67	7	IPR000719
Domain	ADAM_CR	ADAM20 ADAM30	1.87e-03	18	67	2	PF08516
Domain	PROTEIN_KINASE_DOM	IGF1R PDGFRB TBCK LRRK2 PAN3 STK35 NEK9	1.90e-03	493	67	7	PS50011
Domain	-	PLCD3 ESYT3 RASA2 PIK3CG	1.97e-03	148	67	4	2.60.40.150
Domain	-	ADAM20 ADAM30	2.31e-03	20	67	2	4.10.70.10
Domain	Disintegrin	ADAM20 ADAM30	2.55e-03	21	67	2	PF00200
Domain	DISIN	ADAM20 ADAM30	2.55e-03	21	67	2	SM00050
Domain	-	PIAS3 PIAS2	2.55e-03	21	67	2	1.10.720.30
Domain	SAP	PIAS3 PIAS2	2.80e-03	22	67	2	PF02037
Domain	C2_dom	PLCD3 ESYT3 RASA2 PIK3CG	2.86e-03	164	67	4	IPR000008
Domain	SAP	PIAS3 PIAS2	3.06e-03	23	67	2	SM00513
Domain	MetalloPept_cat_dom	ADAMTS9 ADAM20 ADAM30	3.08e-03	81	67	3	IPR024079
Domain	-	ADAMTS9 ADAM20 ADAM30	3.08e-03	81	67	3	3.40.390.10
Domain	SAP	PIAS3 PIAS2	3.61e-03	25	67	2	PS50800
Domain	SAP_dom	PIAS3 PIAS2	3.61e-03	25	67	2	IPR003034
Domain	ACR	ADAM20 ADAM30	4.20e-03	27	67	2	SM00608
Domain	ADAM_Cys-rich	ADAM20 ADAM30	4.20e-03	27	67	2	IPR006586
Domain	ZINC_PROTEASE	ADAMTS9 ADAM20 ADAM30	5.26e-03	98	67	3	PS00142
Pubmed	Inhibition of Stat1-mediated gene activation by PIAS1.	PIAS3 PIAS2 STAT3	2.60e-07	7	69	3	9724754
Pubmed	Expression of inflammatory and fibrogenetic markers in acne hypertrophic scar formation: focusing on role of TGF-β and IGF-1R.	TGFB3 IGF1R	3.88e-06	2	69	2	30167815
Pubmed	JAK/STAT3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3.	IGF1R STAT3	3.88e-06	2	69	2	15998644
Pubmed	The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3.	PIAS3 STAT3	3.88e-06	2	69	2	21812053
Pubmed	Regulation of Id gene expression by type I insulin-like growth factor: roles of Stat3 and the tyrosine 950 residue of the receptor.	IGF1R STAT3	3.88e-06	2	69	2	11463827
Pubmed	Serum starvation and growth factor receptor expression in vascular smooth muscle cells.	IGF1R PDGFRB	3.88e-06	2	69	2	16407661
Pubmed	Human parvovirus B19 NS1 protein modulates inflammatory signaling by activation of STAT3/PIAS3 in human endothelial cells.	PIAS3 STAT3	3.88e-06	2	69	2	18550668
Pubmed	3-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 signaling through the induction of PIAS3.	PIAS3 STAT3	3.88e-06	2	69	2	27324722
Pubmed	Insulin-like growth factor 1 receptor and p38 mitogen-activated protein kinase signals inversely regulate signal transducer and activator of transcription 3 activity to control human dental pulp stem cell quiescence, propagation, and differentiation.	IGF1R STAT3	3.88e-06	2	69	2	24266654
Pubmed	Low PIAS3 expression in malignant mesothelioma is associated with increased STAT3 activation and poor patient survival.	PIAS3 STAT3	3.88e-06	2	69	2	25124686
Pubmed	[Expression of STAT3 and PIAS3 in renal tissues of MRL/lpr mice].	PIAS3 STAT3	3.88e-06	2	69	2	22699062
Pubmed	Specific inhibition of Stat3 signal transduction by PIAS3.	PIAS3 STAT3	3.88e-06	2	69	2	9388184
Pubmed	Melatonin Synergizes with Sorafenib to Suppress Pancreatic Cancer via Melatonin Receptor and PDGFR-β/STAT3 Pathway.	PDGFRB STAT3	3.88e-06	2	69	2	29953970
Pubmed	STAT3/PIAS3 Levels Serve as "Early Signature" Genes in the Development of High-Grade Serous Carcinoma from the Fallopian Tube.	PIAS3 STAT3	3.88e-06	2	69	2	29339537
Pubmed	Deficient Stat3 DNA-binding is associated with high Pias3 expression and a positive anti-apoptotic balance in human end-stage alcoholic and hepatitis C cirrhosis.	PIAS3 STAT3	3.88e-06	2	69	2	16098628
Pubmed	Chromosomal mapping of genes involved in growth control.	IGF1R PDGFRB	3.88e-06	2	69	2	3107886
Pubmed	PIAS3 suppresses acute graft-versus-host disease by modulating effector T and B cell subsets through inhibition of STAT3 activation.	PIAS3 STAT3	3.88e-06	2	69	2	24718277
Pubmed	The association and nuclear translocation of the PIAS3-STAT3 complex is ligand and time dependent.	PIAS3 STAT3	3.88e-06	2	69	2	19903771
Pubmed	Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling.	PDGFRB STAT3	3.88e-06	2	69	2	27980069
Pubmed	Regulation of Id1 protein expression in mouse embryo fibroblasts by the type 1 insulin-like growth factor receptor.	IGF1R STAT3	3.88e-06	2	69	2	12061821
Pubmed	PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population.	ADAMTS9 JAZF1 ADAM30	8.32e-06	20	69	3	19862325
Pubmed	Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.	ADAMTS9 JAZF1 ADAM30	9.69e-06	21	69	3	18591388
Pubmed	Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.	ADAMTS9 JAZF1 ADAM30	1.12e-05	22	69	3	18372903
Pubmed	TEL/platelet-derived growth factor receptor beta activates phosphatidylinositol 3 (PI3) kinase and requires PI3 kinase to regulate the cell cycle.	PDGFRB PIK3CG	1.16e-05	3	69	2	11861293
Pubmed	ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis.	IGF1R STAT3	1.16e-05	3	69	2	32029900
Pubmed	PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth.	IGF1R PDZK1	1.16e-05	3	69	2	23821363
Pubmed	Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.	MFNG PIK3CG	1.16e-05	3	69	2	25808869
Pubmed	The MDA-9/Syntenin/IGF1R/STAT3 Axis Directs Prostate Cancer Invasion.	IGF1R STAT3	1.16e-05	3	69	2	29572229
Pubmed	SIRT1 downregulated FGB expression to inhibit RCC tumorigenesis by destabilizing STAT3.	FBN1 STAT3	1.16e-05	3	69	2	31201813
Pubmed	Suppressor of cytokine signalling-2 limits IGF1R-mediated regulation of epithelial-mesenchymal transition in lung adenocarcinoma.	IGF1R STAT3	1.16e-05	3	69	2	29559623
Pubmed	PIAS genes as disease markers in bipolar disorder.	PIAS3 PIAS2	1.16e-05	3	69	2	30861611
Pubmed	ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3.	PIAS3 STAT3	1.16e-05	3	69	2	14715251
Pubmed	Metastatic cells can escape the proapoptotic effects of TNF-α through increased autocrine IL-6/STAT3 signaling.	IGF1R STAT3	1.16e-05	3	69	2	22194466
Pubmed	Down-regulation of ATBF1 activates STAT3 signaling via PIAS3 in pacing-induced HL-1 atrial myocytes.	PIAS3 STAT3	1.16e-05	3	69	2	24857987
Pubmed	PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.	PDGFRB STAT3	1.16e-05	3	69	2	36045346
Pubmed	Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.	IGF1R STAT3	1.16e-05	3	69	2	26364612
Pubmed	TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3.	PIAS3 STAT3	1.16e-05	3	69	2	28100038
Pubmed	PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.	PIAS3 PIAS2	1.16e-05	3	69	2	12077349
Pubmed	TRIM8 modulates STAT3 activity through negative regulation of PIAS3.	PIAS3 STAT3	1.16e-05	3	69	2	20516148
Pubmed	Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells.	IGF1R PDGFRB	1.16e-05	3	69	2	17568996
Pubmed	Jak1-STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis.	USP6 STAT3	1.16e-05	3	69	2	27440725
Pubmed	MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis.	PIAS3 STAT3	1.16e-05	3	69	2	23322197
Pubmed	Activation of estrogen receptor blocks interleukin-6-inducible cell growth of human multiple myeloma involving molecular cross-talk between estrogen receptor and STAT3 mediated by co-regulator PIAS3.	PIAS3 STAT3	1.16e-05	3	69	2	11429412
Pubmed	Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3.	PIAS3 STAT3	1.16e-05	3	69	2	16368885
Pubmed	Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes.	PIAS3 STAT3	1.16e-05	3	69	2	15572665
Pubmed	A positive feedback loop between miR-181b and STAT3 that affects Warburg effect in colon cancer via regulating PIAS3 expression.	PIAS3 STAT3	1.16e-05	3	69	2	30054984
Pubmed	Ovarian cancer: Stat3, RhoA and IGF-IR as therapeutic targets.	IGF1R STAT3	1.16e-05	3	69	2	22120672
Pubmed	Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways.	PDGFRB STAT3	1.16e-05	3	69	2	23591770
Pubmed	Molecular interactions between STAT3 and protein inhibitor of activated STAT3, and androgen receptor.	PIAS3 STAT3	1.16e-05	3	69	2	12804609
Pubmed	HIV-1 gp120 influences the expression of microRNAs in human monocyte-derived dendritic cells via STAT3 activation.	PIAS3 STAT3	1.16e-05	3	69	2	26116514
Pubmed	Elevation of LncRNA ENST00000453774.1 Prevents Renal Fibrosis by Upregulating FBN1, IGF1R, and KLF7.	IGF1R FBN1	1.16e-05	3	69	2	34614499
Pubmed	Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.	ADAMTS9 JAZF1 SMOC2	1.29e-05	23	69	3	33898467
Pubmed	Genome-wide Identification of Foxf2 Target Genes in Palate Development.	ADAMTS9 JAZF1 SMOC2	1.29e-05	23	69	3	32040930
Pubmed	Poly(ADP-ribose) polymerase as a novel regulator of 17β-estradiol-induced cell growth through a control of the estrogen receptor/IGF-1 receptor/PDZK1 axis.	IGF1R PDZK1	2.32e-05	4	69	2	26183824
Pubmed	Hospicells promote upregulation of the ATP-binding cassette genes by insulin-like growth factor-I via the JAK2/STAT3 signaling pathway in an ovarian cancer cell line.	IGF1R STAT3	2.32e-05	4	69	2	23857432
Pubmed	MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling.	PDGFRB STAT3	2.32e-05	4	69	2	27259262
Pubmed	Migration of dorsal aorta mesenchymal stem cells induced by mouse embryonic circulation.	TGFB3 PDGFRB	2.32e-05	4	69	2	21089075
Pubmed	RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.	IGF1R STAT3	2.32e-05	4	69	2	16382134
Pubmed	Uterine Epithelial LIF Receptors Contribute to Implantation Chamber Formation in Blastocyst Attachment.	LTF STAT3	2.32e-05	4	69	2	34402888
Pubmed	IGF1/IGF1R/STAT3 signaling-inducible IFITM2 promotes gastric cancer growth and metastasis.	IGF1R STAT3	2.32e-05	4	69	2	28223169
Pubmed	PAI-1/PIAS3/Stat3/miR-34a forms a positive feedback loop to promote EMT-mediated metastasis through Stat3 signaling in Non-small cell lung cancer.	PIAS3 STAT3	2.32e-05	4	69	2	28988111
Pubmed	Differential roles of uterine epithelial and stromal STAT3 coordinate uterine receptivity and embryo attachment.	LTF STAT3	2.32e-05	4	69	2	32968170
Pubmed	Activation of IGF1R by DARPP-32 promotes STAT3 signaling in gastric cancer cells.	IGF1R STAT3	2.32e-05	4	69	2	31235784
Pubmed	DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor.	PIAS3 PIAS2	2.32e-05	4	69	2	11477070
Pubmed	SHP2, SOCS3 and PIAS3 Expression Patterns in Medulloblastomas: Relevance to STAT3 Activation and Resveratrol-Suppressed STAT3 Signaling.	PIAS3 STAT3	2.32e-05	4	69	2	28035977
Pubmed	Nuclear Smad6 promotes gliomagenesis by negatively regulating PIAS3-mediated STAT3 inhibition.	PIAS3 STAT3	2.32e-05	4	69	2	29950561
Pubmed	Substrate-bound insulin-like growth factor (IGF)-I-IGF binding protein-vitronectin-stimulated breast cell migration is enhanced by coactivation of the phosphatidylinositide 3-Kinase/AKT pathway by alphav-integrins and the IGF-I receptor.	IGF1R PIK3CG	3.86e-05	5	69	2	18079201
Pubmed	Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells.	PIK3CG STAT3	3.86e-05	5	69	2	19492417
Pubmed	PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.	PIAS3 PIAS2	3.86e-05	5	69	2	15907835
Pubmed	TRIM27 promotes IL-6-induced proliferation and inflammation factor production by activating STAT3 signaling in HaCaT cells.	PIAS3 STAT3	3.86e-05	5	69	2	31747314
Pubmed	Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.	ATP8B1 SMOC2	3.86e-05	5	69	2	19890347
Pubmed	IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer.	IGF1R STAT3	3.86e-05	5	69	2	26840943
Pubmed	SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death.	PIAS3 PIAS2	3.86e-05	5	69	2	28622293
Pubmed	STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation.	LTF STAT3	3.86e-05	5	69	2	27358915
Pubmed	Correlative analyses of the expression levels of PIAS3, p-SHP2, SOCS1 and SOCS3 with STAT3 activation in human astrocytomas.	PIAS3 STAT3	3.86e-05	5	69	2	28035384
Pubmed	Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.	IGF1R STAT3	3.86e-05	5	69	2	17975158
Pubmed	SUMO Modification Reverses Inhibitory Effects of Smad Nuclear Interacting Protein-1 in TGF-β Responses.	PIAS3 PIAS2	3.86e-05	5	69	2	27703003
Pubmed	Testing the association of novel meta-analysis-derived diabetes risk genes with type II diabetes and related metabolic traits in Asian Indian Sikhs.	ADAMTS9 JAZF1	5.79e-05	6	69	2	19247373
Pubmed	Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner.	PIAS3 PIAS2	5.79e-05	6	69	2	16029420
Pubmed	SUMOylation of RORalpha potentiates transcriptional activation function.	PIAS3 PIAS2	5.79e-05	6	69	2	19041634
Pubmed	Elucidating mechanisms of osteogenesis in human adipose-derived stromal cells via microarray analysis.	TGFB3 PDGFRB	5.79e-05	6	69	2	20613589
Pubmed	Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.	ADAMTS9 JAZF1	5.79e-05	6	69	2	18567820
Pubmed	Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.	FBN1 PDGFRB	5.79e-05	6	69	2	7873879
Pubmed	Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks.	IGF1R PDGFRB	5.79e-05	6	69	2	23861540
Pubmed	A SUMOylation-dependent pathway regulates SIRT1 transcription and lung cancer metastasis.	PIAS3 PIAS2	5.79e-05	6	69	2	23704280
Pubmed	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	CD244 LRRK2 CD40 JAZF1 ADAM30 STAT3	6.16e-05	342	69	6	23128233
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	ESYT3 CLCN6 FBXO3 SMOC2	7.76e-05	113	69	4	34474245
Pubmed	Developmental expression of latent transforming growth factor beta binding protein 2 and its requirement early in mouse development.	TGFB3 FBN1	8.09e-05	7	69	2	10848613
Pubmed	The mouse C/EBPdelta gene promoter is regulated by STAT3 and Sp1 transcriptional activators, chromatin remodeling and c-Myc repression.	PIAS2 STAT3	8.09e-05	7	69	2	17471507
Pubmed	Phospho-regulated SUMO interaction modules connect the SUMO system to CK2 signaling.	PIAS3 PIAS2	8.09e-05	7	69	2	19217413
Pubmed	Physical and functional interactions between STAT3 and KAP1.	PIAS3 STAT3	8.09e-05	7	69	2	18037959
Pubmed	Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene.	MYO7A STAT3	8.09e-05	7	69	2	15254021
Pubmed	The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons.	TGFB3 RELN IGF1R	9.34e-05	44	69	3	27224923
Pubmed	Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.	TGFB3 FBN1	1.08e-04	8	69	2	23055981
Pubmed	XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling.	TGFB3 PDGFRB	1.08e-04	8	69	2	26315405
Pubmed	ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation.	PIAS3 PIAS2	1.08e-04	8	69	2	11117529
Pubmed	Transforming growth factors beta 1, beta 2, and beta 3 messenger RNA and protein expression in mouse uterus and vagina during estrogen-induced growth: a comparison to other estrogen-regulated genes.	TGFB3 LTF	1.08e-04	8	69	2	7819129
Pubmed	Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP.	PIAS3 PIAS2	1.08e-04	8	69	2	16522640
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ATP6V1H IGF1R PIAS3 PDGFRB CD40 RBM15B SLFN5 LTF PIAS2 STAT3	1.26e-04	1203	69	10	29180619
Pubmed	Positional cloning of the combined hyperlipidemia gene Hyplip1.	PIAS3 PDZK1	1.38e-04	9	69	2	11753387
GeneFamily	Zinc fingers MIZ-type	PIAS3 PIAS2	1.82e-04	7	54	2	85
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000	TGFB3 FBN1 PDGFRB ADAMTS9 SMOC2 POLG2 ADGRL3	1.64e-05	261	66	7	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4	TGFB3 VSNL1 FBN1 NSMF TRMT2A MYO7A LRRK2 JAZF1 L2HGDH ATP8B1 SMOC2 NEK9 ADGRL3	4.43e-05	1148	66	13	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200	VSNL1 FBN1 PDGFRB SMOC2 ADGRL3	9.15e-05	146	66	5	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	VSNL1 FBN1 PDGFRB ADGRL3	9.23e-05	76	66	4	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_100
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 PDGFRB ADAMTS9 DIO2 SMOC2 ADGRL3	3.91e-07	182	69	6	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|343B / Donor, Lineage, Cell class and subclass (all cells)	TRMT2A CD244 RASA2 DIS3L THAP9	4.56e-06	157	69	5	0362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCell	Tuft-tuft-1\|World / Class top	NBAS MFNG MYO7A DIS3L TSPYL5	6.34e-06	168	69	5	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS9 PDZK1 LRRK2 SMOC2 ADGRL3	7.94e-06	176	69	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB3 FBN1 PDGFRB DIO2 SMOC2	8.39e-06	178	69	5	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB3 FBN1 PDGFRB DIO2 SMOC2	8.39e-06	178	69	5	d348a9550db940d204706529759dc51e30506b5f
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	ZNF10 CARF VPS8 LRRK2 BCL2L2	8.62e-06	179	69	5	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TGFB3 PDGFRB ADAMTS9 ATP8B1 ADGRL3	8.62e-06	179	69	5	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TGFB3 PDGFRB ADAMTS9 SMOC2 ADGRL3	9.10e-06	181	69	5	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 PDGFRB ADAM20 DIO2 SMOC2	9.59e-06	183	69	5	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN MFNG MYO7A ADAMTS9 CD40	1.01e-05	185	69	5	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS9 PDZK1 LRRK2 SMOC2 ADGRL3	1.04e-05	186	69	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	TGFB3 PDGFRB ADAMTS9 SMOC2 ADGRL3	1.18e-05	191	69	5	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB3 FBN1 PDGFRB DIO2 SMOC2	1.24e-05	193	69	5	92048d2e9e43513e6185e09553be3ee47d7e5207
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB3 FBN1 PDGFRB DIO2 SMOC2	1.24e-05	193	69	5	ac088c8f27b5b1888610e461ff45870ca60da886
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFB3 VSNL1 FBN1 PDGFRB ADGRL3	1.40e-05	198	69	5	b2d295e330772bd8e24da356c75564b4297ea9c5
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFB3 VSNL1 FBN1 PDGFRB ADGRL3	1.40e-05	198	69	5	ce59ee3d970397eb62d6387699c6c6cd65457898
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFB3 VSNL1 FBN1 PDGFRB ADGRL3	1.40e-05	198	69	5	3ffaea4b44067d69f954b2bd3119c88a55ab232a
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TGFB3 PDGFRB ADAMTS9 SMOC2 ADGRL3	1.44e-05	199	69	5	8ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 PDGFRB DIO2 SMOC2 ADGRL3	1.44e-05	199	69	5	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	COVID-19_Severe-immature_Neutrophil\|COVID-19_Severe / Disease condition and Cell class	IGF1R FBN1 LTF POLQ SLC27A2	1.44e-05	199	69	5	f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCell	COVID-19_Severe-immature_Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	IGF1R FBN1 LTF POLQ SLC27A2	1.44e-05	199	69	5	42ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TGFB3 FBN1 PDGFRB DIO2 SMOC2	1.47e-05	200	69	5	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	LPS_IL1RA\|World / Treatment groups by lineage, cell group, cell type	ADAMTS9 DNAJC25 CD40 ADGRL3 STAT3	1.47e-05	200	69	5	a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	TGFB3 VSNL1 FBN1 PDGFRB DIO2	1.47e-05	200	69	5	082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	TGFB3 FBN1 PDGFRB DIO2 SMOC2	1.47e-05	200	69	5	4f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	TGFB3 FBN1 PDGFRB DIO2 SMOC2	1.47e-05	200	69	5	ca777a7d001848f6d01c613ff2bda7e4f3e20521
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TGFB3 FBN1 PDGFRB DIO2 SMOC2	1.47e-05	200	69	5	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	TGFB3 VSNL1 FBN1 PDGFRB DIO2	1.47e-05	200	69	5	731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 PDGFRB DIO2 SMOC2 ADGRL3	1.47e-05	200	69	5	29054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TGFB3 PDGFRB ADAMTS9 SMOC2 ADGRL3	1.47e-05	200	69	5	fc2fc3bfcf1ad9bfb9fe07bbed8068126930bee6
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	TGFB3 FBN1 PDGFRB DIO2 SMOC2	1.47e-05	200	69	5	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	(5)_Fibroblast-B_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	TGFB3 VSNL1 FBN1 PDGFRB DIO2	1.47e-05	200	69	5	9bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NSMF ADAMTS9 SMOC2 LIPI	4.54e-05	127	69	4	9bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PDGFRB SMOC2 ADGRL3	1.09e-04	159	69	4	cfb4a8c8aac34b1a857956d98382d487abcf5444
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PDGFRB SMOC2 ADGRL3	1.09e-04	159	69	4	a75ab494959575143cefdaec99e7aee3f318d559
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	PDGFRB ADAMTS9 SMOC2 ADGRL3	1.11e-04	160	69	4	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PDGFRB ADAMTS9 SMOC2 ADGRL3	1.11e-04	160	69	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	PDGFRB ADAMTS9 SMOC2 ADGRL3	1.14e-04	161	69	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	droplet-Lung-nan-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCD3 NBAS RELN ENDOU	1.19e-04	163	69	4	5efecdd8a069a822bc9d35b407092925a865e629
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCD3 NBAS RELN ENDOU	1.19e-04	163	69	4	0d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLCD3 NBAS RELN ENDOU	1.22e-04	164	69	4	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLCD3 NBAS RELN ENDOU	1.22e-04	164	69	4	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PIAS3 PDGFRB SMOC2 ADGRL3	1.25e-04	165	69	4	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PIAS3 PDGFRB SMOC2 ADGRL3	1.25e-04	165	69	4	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	TGFB3 FBN1 PDGFRB POLQ	1.31e-04	167	69	4	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	TGFB3 FBN1 PDGFRB LTF	1.34e-04	168	69	4	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDZK1 VPS8 PAQR7 SLC27A2	1.44e-04	171	69	4	48fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCell	droplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDZK1 VPS8 PAQR7 SLC27A2	1.44e-04	171	69	4	05fcc72df50a380a913821b5781d9621df37d328
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	PDGFRB ADAMTS9 SMOC2 POLQ	1.47e-04	172	69	4	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF1R RASA2 LRRK2 LTF	1.47e-04	172	69	4	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDGFRB ADAMTS9 ATP8B1 ADGRL3	1.54e-04	174	69	4	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF1R CD244 PDGFRB ATP8B1	1.64e-04	177	69	4	9b4c1ca5c6fca9a7a936dad49a04155903ef9c32
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF1R CD244 JAZF1 ATP8B1	1.64e-04	177	69	4	c1f838e425ebb04482829b1957e3c1347127e6de
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF1R CD244 ADAMTS9 ATP8B1	1.68e-04	178	69	4	cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDZK1 LRRK2 ADGRL3 SLC27A2	1.68e-04	178	69	4	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PIAS3 BCL2L2 ZNF681 SLC27A2	1.71e-04	179	69	4	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 PDGFRB DIO2 SMOC2	1.75e-04	180	69	4	39ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DIS3L BCL2L2 STK35 NEK9	1.79e-04	181	69	4	f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	TGFB3 PDGFRB ADAMTS9 ADGRL3	1.79e-04	181	69	4	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS9 PDZK1 LRRK2 SMOC2	1.82e-04	182	69	4	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDZK1 LRRK2 SMOC2 ADGRL3	1.86e-04	183	69	4	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PDGFRB SLFN5 SMOC2	1.86e-04	183	69	4	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PDGFRB SLFN5 SMOC2	1.86e-04	183	69	4	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PDGFRB SLFN5 SMOC2	1.86e-04	183	69	4	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGFB3 FBN1 DIO2 SMOC2	1.90e-04	184	69	4	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	CLCN6 DNAJC25 CARF ZNF681	1.90e-04	184	69	4	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PDGFRB ADAM30 SMOC2	1.90e-04	184	69	4	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARF MCM3 POLQ STK35	1.90e-04	184	69	4	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	TGFB3 CD244 PDGFRB SMOC2	1.94e-04	185	69	4	e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDGFRB ADAMTS9 PLEKHA2 ATP8B1	1.94e-04	185	69	4	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 DIO2 SMOC2 ADGRL3	1.94e-04	185	69	4	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	CLCN6 DNAJC25 CARF ZNF681	1.94e-04	185	69	4	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	droplet-Bladder-nan-24m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MFNG ENDOU SLFN5	1.94e-04	185	69	4	90caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PIAS3 TBCK LRRK2 SMOC2	1.94e-04	185	69	4	daea170d827226dda6750bf1838ffd82f070c4d4
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FBN1 PDGFRB ADAMTS9 ADGRL3	1.98e-04	186	69	4	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN MFNG MYO7A CD40	1.98e-04	186	69	4	9d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	TGFB3 FBN1 PDGFRB SMOC2	1.98e-04	186	69	4	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN IGF1R PDGFRB ADAMTS9	2.02e-04	187	69	4	b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	IGF1R DIS3L ATP8B1 SLC27A2	2.02e-04	187	69	4	a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN IGF1R PDGFRB ADAMTS9	2.02e-04	187	69	4	9fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN IGF1R PDGFRB ADAMTS9	2.02e-04	187	69	4	e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGFB3 VSNL1 TSPYL5 SMOC2	2.02e-04	187	69	4	8bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 PDGFRB DIO2 SMOC2	2.02e-04	187	69	4	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGFB3 VSNL1 TSPYL5 SMOC2	2.02e-04	187	69	4	3cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCell	IPF-Stromal-SMC\|World / Disease state, Lineage and Cell class	PDGFRB ADAMTS9 SMOC2 ADGRL3	2.06e-04	188	69	4	b66264e8f8d536ed2beec31e6746c687718f239b
ToppCell	Pericytes-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	TGFB3 FBN1 PDGFRB ADGRL3	2.06e-04	188	69	4	f16ff998393bf1954bbf10caab15173bdb104ac1
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 PDGFRB DIO2 SMOC2	2.06e-04	188	69	4	6c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 DIO2 SMOC2 ADGRL3	2.06e-04	188	69	4	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	CF-Lymphoid-T_cell_&_NK_cell\|Lymphoid / Disease state, Lineage and Cell class	CD244 TBC1D2B SLFN5 SLC27A2	2.06e-04	188	69	4	15057036b46c9df621ec4955aa94ca3036245d45
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 PDGFRB DIO2 SMOC2	2.06e-04	188	69	4	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	IPF-Stromal-SMC\|IPF / Disease state, Lineage and Cell class	PDGFRB ADAMTS9 SMOC2 ADGRL3	2.06e-04	188	69	4	e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCell	P07-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MFNG ENDOU SLFN5 PAQR7	2.15e-04	190	69	4	5d25e40bc2cca314f4265e4001a546e6d99e2a79
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VSNL1 FBN1 PDGFRB SMOC2	2.15e-04	190	69	4	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PDGFRB SMOC2 ADGRL3	2.15e-04	190	69	4	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDGFRB ADAMTS9 ATP8B1 ADGRL3	2.15e-04	190	69	4	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGFB3 FBN1 PDGFRB SMOC2	2.19e-04	191	69	4	2b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGFB3 FBN1 DIO2 SMOC2	2.19e-04	191	69	4	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PDGFRB ATP8B1 SMOC2	2.19e-04	191	69	4	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	NBAS TBCK POLQ SLC27A2	2.19e-04	191	69	4	9454f642c3621370fa23640b631301346b300950
Drug	tetrathiomolybdate	IGF1R FBN1 PDGFRB CD40 BCL2L2	3.65e-06	78	68	5	ctd:C020809
Disease	Crohn's disease (is_implicated_in)	LRRK2 CD40 STAT3	3.97e-05	30	65	3	DOID:8778 (is_implicated_in)
Disease	Gastrointestinal Hemorrhage	RELN LTF	1.70e-04	9	65	2	C0017181
Disease	Fibrosis	PIK3CG STAT3 SLC27A2	1.86e-04	50	65	3	C0016059
Disease	Cirrhosis	PIK3CG STAT3 SLC27A2	1.86e-04	50	65	3	C1623038
Disease	rheumatoid arthritis (is_implicated_in)	CD244 CD40 STAT3	2.89e-04	58	65	3	DOID:7148 (is_implicated_in)
Disease	complex trait	NBAS IGF1R RASA2 JAZF1 ATG4C	3.32e-04	271	65	5	EFO_0010578
Disease	hematologic cancer (implicated_via_orthology)	PIAS3 PIAS2	3.67e-04	13	65	2	DOID:2531 (implicated_via_orthology)
Disease	skin melanoma (is_marker_for)	CD40 STAT3	3.67e-04	13	65	2	DOID:8923 (is_marker_for)
Disease	Crohn's disease	CD244 LRRK2 CD40 JAZF1 ADAM30 STAT3	4.23e-04	441	65	6	EFO_0000384
Disease	Kuhnt-Junius degeneration (is_marker_for)	IGF1R PDGFRB	4.27e-04	14	65	2	DOID:10873 (is_marker_for)
Disease	lymphocyte:monocyte ratio	RASA2 PDGFRB JAZF1 LTF PAN3	4.38e-04	288	65	5	EFO_0600088
Disease	Endometrioma	FBN1 LRRK2 DIO2 LTF	4.46e-04	161	65	4	C0269102
Disease	Endometriosis	FBN1 LRRK2 DIO2 LTF	4.46e-04	161	65	4	C0014175
Disease	renal cell carcinoma (is_implicated_in)	PDGFRB LTF STAT3	4.82e-04	69	65	3	DOID:4450 (is_implicated_in)
Disease	ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis	CD244 LRRK2 CD40 JAZF1 STAT3	4.88e-04	295	65	5	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Disease	diabetic neuropathy (biomarker_via_orthology)	TGFB3 LRRK2	6.36e-04	17	65	2	DOID:9743 (biomarker_via_orthology)
Disease	Congenital hernia of foramen of Morgagni	IGF1R STAT3	7.98e-04	19	65	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	IGF1R STAT3	7.98e-04	19	65	2	C0265700
Disease	atherosclerosis (biomarker_via_orthology)	CD40 STAT3	8.85e-04	20	65	2	DOID:1936 (biomarker_via_orthology)
Disease	Congenital diaphragmatic hernia	IGF1R STAT3	9.77e-04	21	65	2	C0235833
Disease	cerebrospinal fluid biomarker measurement	ATP6V1H PDGFRB LTF	1.26e-03	96	65	3	EFO_0006794
Disease	Acute Confusional Senile Dementia	RELN VSNL1 IGF1R	1.38e-03	99	65	3	C0546126
Disease	Alzheimer's Disease, Focal Onset	RELN VSNL1 IGF1R	1.38e-03	99	65	3	C0750900
Disease	Alzheimer Disease, Early Onset	RELN VSNL1 IGF1R	1.38e-03	99	65	3	C0750901
Disease	Presenile dementia	RELN VSNL1 IGF1R	1.38e-03	99	65	3	C0011265
Disease	Alzheimer Disease, Late Onset	RELN VSNL1 IGF1R	1.38e-03	99	65	3	C0494463
Disease	Familial Alzheimer Disease (FAD)	RELN VSNL1 IGF1R	1.42e-03	100	65	3	C0276496
Disease	Alzheimer's Disease	RELN VSNL1 IGF1R	1.46e-03	101	65	3	C0002395
Disease	Endogenous Hyperinsulinism	FBN1 CD40	1.50e-03	26	65	2	C1257963
Disease	Exogenous Hyperinsulinism	FBN1 CD40	1.50e-03	26	65	2	C1257964
Disease	Compensatory Hyperinsulinemia	FBN1 CD40	1.50e-03	26	65	2	C1257965
Disease	pancreatic ductal adenocarcinoma (is_marker_for)	TGFB3 PIK3CG	1.62e-03	27	65	2	DOID:3498 (is_marker_for)
Disease	lifestyle measurement, depressive symptom measurement	DIS3L ATP8B1 USP48	1.63e-03	105	65	3	EFO_0007006, EFO_0010724
Disease	glucose metabolism disease (implicated_via_orthology)	IGF1R DIO2	1.74e-03	28	65	2	DOID:4194 (implicated_via_orthology)
Disease	stimulant use measurement	NBAS VSNL1	1.74e-03	28	65	2	EFO_0600076
Disease	Hyperinsulinism	FBN1 CD40	1.74e-03	28	65	2	C0020459
Disease	Hyperglycemia, Postprandial	FBN1 CD40	2.00e-03	30	65	2	C1855520
Disease	Hyperglycemia	FBN1 CD40	2.00e-03	30	65	2	C0020456
Disease	migraine disorder, glucose measurement	PLCD3 IGF1R	2.13e-03	31	65	2	EFO_0004468, MONDO_0005277

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKLYFGQKCPRVNGV	ESYT3	161	A0FGR9
PGNIFRLKYCGNLVV	ADAM20	401	O43506
KVFLCPGLLKGVYQS	ADGRL3	131	Q9HAR2
KLRQKGYVCGAGPGE	BCL2L2	21	Q92843
GNCRKLGAPKVFYIA	HSD11B1L	71	Q7Z5J1
IVRTPEGNIKLYCKG	ATP8B1	606	O43520
LEYCVGIIGGKPKQS	ATG4C	316	Q96DT6
VIGRNPIKIGYGKAN	RBM15B	401	Q8NDT2
RGKICEAKNLLPYLG	RASA2	41	Q15283
PKLCRLAKGENGYGF	PDZK1	376	Q5T2W1
YNKYIQKPGLLGRTC	PAQR7	191	Q86WK9
CIVQRQKIAYLGGKG	DIO2	231	Q92813
CGQLGVGNYKKRLGI	NEK9	626	Q8TD19
VGNYKKRLGINLLGG	NEK9	631	Q8TD19
ALYEKGLQNGVPGLR	L2HGDH	151	Q9H9P8
PVPGCKKRYKNVNGI	JAZF1	176	Q86VZ6
CQYGPRRKGFQLKKV	CARF	286	Q8N187
RKYGGAKLNRLNPGN	IGF1R	886	P08069
AGGFQQRQGLKYCLP	FBXO3	181	Q9UK99
IARPGKVCQLSLGGY	ENDOU	366	P21128
NRFIGNPGIQKCGLK	LRRK2	551	Q5S007
CQGGPGHLYLLKNKV	NSMF	411	Q6X4W1
NKRLPYGLAQIGVCF	POLG2	201	Q9UHN1
SLTYLRPLQGQKCGG	NBAS	1441	A2RRP1
RPLQGQKCGGAYQIG	NBAS	1446	A2RRP1
KPGYVLQFKLNIGCA	RELN	1296	P78509
QVVGTYRCLPGKKGG	MCM3	236	P25205
VPGGAAVGVKLKYCR	PAN3	36	Q58A45
DIKGGYQKPQICDLL	DNAJC25	231	Q9H1X3
NIPGLGYVLKRCGNK	ADAM30	391	Q9UKF2
NRPEPKNGGKYCVGR	ADAMTS9	616	Q9P2N4
GSGIPEVKCYLNGVK	CLCN6	156	P51797
KGPYCLLQGIGRRKD	C3orf84	66	H3BNL1
QVDPICGKGYSRIKG	FBN1	891	P35555
AYLKNKDGLVISCGP	DIS3L	901	Q8TF46
GRGKYKKGFSVNPRC	POLQ	2281	O75417
TVYRLLKCAPRGKNG	FEM1A	521	Q9BSK4
LLLLKVYQGKGCQGS	CD244	11	Q9BZW8
GYIIECKLGGRLQPS	MFNG	236	O00587
NLLGACTKGGPIYII	PDGFRB	666	P09619
CIKVNGKLFPLPGYA	PIAS2	231	O75928
GCKQFIRGKPIRFGY	PGBD3	281	Q8N328
GPPLIKSGYCVKQGN	PLEKHA2	196	Q9HB19
RLGKYKGGTCAVAAP	TRMT2A	261	Q8IZ69
YPRGKRVIEQLGGKQ	ATP6V1H	421	Q9UI12
AGKCGLVPVLAENYK	LTF	421	P02788
SCPRLGYQAKLFKGV	LIPI	296	Q6XZB0
NGYCVRVPKGEVGLL	SLC27A2	411	O14975
FRCNYLALVGGGKKP	WDR45B	61	Q5MNZ6
QRILQDPVYGKGKLG	VPS8	1191	Q8N3P4
QKLCPGGQLPFLLYG	CLIC1	56	O00299
GALLNLQIYCGKAPA	PIK3CG	426	P48736
LFVKVNGKLCPLPGY	PIAS3	211	Q9Y6X2
GPQGPKGAEKRYLCQ	ZFP92	141	A6NM28
APAGGAAYVKRLCKG	STK35	11	Q8TDR2
YKGFLKDCPSGRLNL	VSNL1	31	P62760
FNSRNCYGKGLKGPL	THAP9	521	Q9H5L6
GRFLVNGQCGYVLKP	PLCD3	626	Q8N3E9
KARDLYKGRQLQGCP	SMOC2	291	Q9H3U7
KLLGPGVNYSGCQIT	STAT3	531	P40763
KYPRICILDGGINKI	TBCK	866	Q8TEA7
SGKYGGNCLLPAQLV	ZNF10	166	P21506
KVQKGGYNGLNQCLP	ZNF681	121	Q96N22
RYGGGPRLTVKALCK	USP48	541	Q86UV5
VRGEGQKAKLYCAPI	TRBV16	31	A0A087WV62
RLCGYLQKLSGKGPL	TBC1D2B	36	Q9UPU7
QKLVNKGGYTGRLCI	SLFN5	476	Q08AF3
AKQRYIGGKNLPTRG	TGFB3	181	P10600
RGGKTLCKGYRQAPP	USP6	376	P35125
KYCDPNLGLRVQQKG	CD40	81	P25942
NKVLIKEYGCGPSGQ	TSPYL5	306	Q86VY4
GVKPAYKQGDLRGTC	MYO7A	691	Q13402