Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	diacylglycerol O-acyltransferase activity	MOGAT2 AWAT2 DGAT2L6	1.91e-06	8	66	3	GO:0004144
GeneOntologyMolecularFunction	volume-sensitive anion channel activity	LRRC8E LRRC8C LRRC8A	2.86e-06	9	66	3	GO:0005225
GeneOntologyMolecularFunction	acylglycerol O-acyltransferase activity	MOGAT2 LPCAT3 AWAT2 DGAT2L6	3.65e-06	32	66	4	GO:0016411
GeneOntologyMolecularFunction	O-acyltransferase activity	MOGAT2 LPCAT3 AWAT2 DGAT2L6	4.32e-05	59	66	4	GO:0008374
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	SI MGAM2	1.07e-04	5	66	2	GO:0004558
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	NAT8B MOGAT2 LPCAT3 CERS3 AWAT2 DGAT2L6	1.35e-04	238	66	6	GO:0016747
GeneOntologyMolecularFunction	acyltransferase activity	NAT8B FBXO6 LMO7 MOGAT2 LPCAT3 CERS3 UBR4 BFAR AWAT2 DGAT2L6	2.16e-04	775	66	10	GO:0016746
GeneOntologyMolecularFunction	alpha-glucosidase activity	SI MGAM2	2.24e-04	7	66	2	GO:0090599
GeneOntologyMolecularFunction	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	MAN1A1 MAN1C1	2.97e-04	8	66	2	GO:0004571
GeneOntologyMolecularFunction	2-acylglycerol O-acyltransferase activity	MOGAT2 AWAT2	2.97e-04	8	66	2	GO:0003846
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	MAN1A1 MAN1C1 SI MGAM2	3.76e-04	103	66	4	GO:0004553
GeneOntologyMolecularFunction	arginine binding	SLC38A9 NOS2	3.82e-04	9	66	2	GO:0034618
GeneOntologyMolecularFunction	mannosyl-oligosaccharide mannosidase activity	MAN1A1 MAN1C1	4.76e-04	10	66	2	GO:0015924
GeneOntologyMolecularFunction	alpha-mannosidase activity	MAN1A1 MAN1C1	1.10e-03	15	66	2	GO:0004559
GeneOntologyMolecularFunction	glucosidase activity	SI MGAM2	1.10e-03	15	66	2	GO:0015926
GeneOntologyMolecularFunction	mannosidase activity	MAN1A1 MAN1C1	1.25e-03	16	66	2	GO:0015923
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	MAN1A1 MAN1C1 SI MGAM2	1.32e-03	144	66	4	GO:0016798
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	LRRC8E LRRC8C SLC4A8 LRRC8A	1.57e-03	151	66	4	GO:0008509
GeneOntologyMolecularFunction	amino acid binding	SLC38A9 MTR NOS2	1.82e-03	73	66	3	GO:0016597
GeneOntologyMolecularFunction	growth factor activity	TGFB2 GDF2 MSTN GDF11	2.58e-03	173	66	4	GO:0008083
GeneOntologyBiologicalProcess	cyclic-GMP-AMP transmembrane import across plasma membrane	LRRC8E LRRC8C LRRC8A	1.65e-06	8	65	3	GO:0140361
GeneOntologyBiologicalProcess	monoacylglycerol biosynthetic process	MOGAT2 AWAT2 DGAT2L6	2.48e-06	9	65	3	GO:0006640
GeneOntologyBiologicalProcess	guanine nucleotide transmembrane transport	LRRC8E LRRC8C LRRC8A	3.53e-06	10	65	3	GO:1903790
GeneOntologyBiologicalProcess	cyclic nucleotide transport	LRRC8E LRRC8C LRRC8A	4.84e-06	11	65	3	GO:0070729
GeneOntologyBiologicalProcess	guanine nucleotide transport	LRRC8E LRRC8C LRRC8A	4.84e-06	11	65	3	GO:0001408
GeneOntologyBiologicalProcess	monoacylglycerol metabolic process	MOGAT2 AWAT2 DGAT2L6	1.62e-05	16	65	3	GO:0046462
GeneOntologyBiologicalProcess	aspartate transmembrane transport	LRRC8E LRRC8C LRRC8A	4.41e-05	22	65	3	GO:0015810
GeneOntologyBiologicalProcess	acylglycerol acyl-chain remodeling	AWAT2 DGAT2L6	5.84e-05	4	65	2	GO:0036155
GeneOntologyBiologicalProcess	C4-dicarboxylate transport	LRRC8E LRRC8C LRRC8A	1.03e-04	29	65	3	GO:0015740
GeneOntologyBiologicalProcess	regulation of protein secretion	UNC13B TGFB2 SLC8B1 UTS2 LRRC8A NOS2 ALOX5	1.14e-04	350	65	7	GO:0050708
GeneOntologyBiologicalProcess	nucleotide transmembrane transport	LRRC8E LRRC8C LRRC8A	1.26e-04	31	65	3	GO:1901679
GeneOntologyBiologicalProcess	protein secretion	UNC13B TGFB2 SLC8B1 SLC4A8 UTS2 LRRC8A NOS2 ALOX5	1.28e-04	480	65	8	GO:0009306
GeneOntologyBiologicalProcess	establishment of protein localization to extracellular region	UNC13B TGFB2 SLC8B1 SLC4A8 UTS2 LRRC8A NOS2 ALOX5	1.34e-04	483	65	8	GO:0035592
GeneOntologyBiologicalProcess	protein localization to extracellular region	UNC13B TGFB2 SLC8B1 SLC4A8 UTS2 LRRC8A NOS2 ALOX5	1.47e-04	490	65	8	GO:0071692
GeneOntologyBiologicalProcess	mononuclear cell migration	PLA2G7 SLC8B1 CCR1 MSTN ZAP70 ALOX5	1.61e-04	258	65	6	GO:0071674
GeneOntologyBiologicalProcess	leukocyte chemotaxis	TGFB2 PLA2G7 SLC8B1 CCR1 MSTN ALOX5	1.94e-04	267	65	6	GO:0030595
GeneOntologyBiologicalProcess	cellular homeostasis	UNC13B TGFB2 LRRC8E SLC8B1 SLC4A8 ATP6V0E1 LRRC8A CCR1 GDF2 MSTN NOS2	2.25e-04	981	65	11	GO:0019725
GeneOntologyBiologicalProcess	ubiquitin-dependent glycoprotein ERAD pathway	MAN1A1 MAN1C1	2.70e-04	8	65	2	GO:0097466
GeneOntologyBiologicalProcess	protein deglycosylation involved in glycoprotein catabolic process	MAN1A1 MAN1C1	2.70e-04	8	65	2	GO:0035977
GeneOntologyBiologicalProcess	protein alpha-1,2-demannosylation	MAN1A1 MAN1C1	2.70e-04	8	65	2	GO:0036508
GeneOntologyBiologicalProcess	protein demannosylation	MAN1A1 MAN1C1	2.70e-04	8	65	2	GO:0036507
GeneOntologyBiologicalProcess	alkanesulfonate transmembrane transport	LRRC8C LRRC8A	2.70e-04	8	65	2	GO:0042918
GeneOntologyBiologicalProcess	taurine transmembrane transport	LRRC8C LRRC8A	2.70e-04	8	65	2	GO:0015734
GeneOntologyBiologicalProcess	mannose trimming involved in glycoprotein ERAD pathway	MAN1A1 MAN1C1	2.70e-04	8	65	2	GO:1904382
GeneOntologyBiologicalProcess	purine-containing compound transmembrane transport	LRRC8E LRRC8C LRRC8A	2.72e-04	40	65	3	GO:0072530
GeneOntologyBiologicalProcess	purine ribonucleotide transport	LRRC8E LRRC8C LRRC8A	2.72e-04	40	65	3	GO:0015868
GeneOntologyBiologicalProcess	glycoprotein catabolic process	MAN1A1 FBXO6 MAN1C1	2.92e-04	41	65	3	GO:0006516
GeneOntologyBiologicalProcess	adenine nucleotide transport	LRRC8E LRRC8C LRRC8A	3.14e-04	42	65	3	GO:0051503
GeneOntologyBiologicalProcess	response to endoplasmic reticulum stress	MAN1A1 FBXO6 MAN1C1 LPCAT3 BFAR ALOX5	3.31e-04	295	65	6	GO:0034976
GeneOntologyBiologicalProcess	positive regulation of SMAD protein signal transduction	TGFB2 GDF2 GDF11	3.37e-04	43	65	3	GO:0060391
GeneOntologyBiologicalProcess	protein hexamerization	LRRC8C LRRC8A	3.47e-04	9	65	2	GO:0034214
GeneOntologyBiologicalProcess	purine nucleotide transport	LRRC8E LRRC8C LRRC8A	3.61e-04	44	65	3	GO:0015865
GeneOntologyBiologicalProcess	response to osmotic stress	LRRC8E LRRC8C LRRC8A USP15	4.47e-04	113	65	4	GO:0006970
GeneOntologyBiologicalProcess	negative regulation of response to endoplasmic reticulum stress	LPCAT3 BFAR ALOX5	4.96e-04	49	65	3	GO:1903573
GeneOntologyBiologicalProcess	leukocyte migration	TGFB2 PLA2G7 SLC8B1 CCR1 MSTN ZAP70 ALOX5	5.18e-04	449	65	7	GO:0050900
GeneOntologyBiologicalProcess	nucleotide transport	LRRC8E LRRC8C LRRC8A	5.27e-04	50	65	3	GO:0006862
GeneOntologyBiologicalProcess	amino acid transmembrane transport	LRRC8E LRRC8C SLC38A9 LRRC8A	5.61e-04	120	65	4	GO:0003333
GeneOntologyBiologicalProcess	response to glycoprotein	MAN1A1 MAN1C1	6.32e-04	12	65	2	GO:1904587
GeneOntologyBiologicalProcess	regulation of insulin secretion	SLC8B1 UTS2 LRRC8A NOS2 ALOX5	8.07e-04	231	65	5	GO:0050796
GeneOntologyBiologicalProcess	carbohydrate metabolic process	MAN1A1 MOGAT2 MAN1C1 SI B3GALT5 GDF2 G6PD MGAM2	9.28e-04	646	65	8	GO:0005975
Domain	LRRC8_Pannexin-like	LRRC8E LRRC8C LRRC8A	3.47e-07	5	62	3	IPR021040
Domain	Pannexin_like	LRRC8E LRRC8C LRRC8A	3.47e-07	5	62	3	PF12534
Domain	DAGAT	MOGAT2 AWAT2 DGAT2L6	1.21e-06	7	62	3	PF03982
Domain	DAGAT	MOGAT2 AWAT2 DGAT2L6	1.21e-06	7	62	3	IPR007130
Domain	TGFb_propeptide	TGFB2 GDF2 MSTN GDF11	2.12e-06	28	62	4	PF00688
Domain	TGF-b_N	TGFB2 GDF2 MSTN GDF11	2.12e-06	28	62	4	IPR001111
Domain	TGF-beta-rel	TGFB2 GDF2 MSTN GDF11	3.69e-06	32	62	4	IPR015615
Domain	TGFb_CS	TGFB2 GDF2 MSTN GDF11	3.69e-06	32	62	4	IPR017948
Domain	TGFB	TGFB2 GDF2 MSTN GDF11	6.70e-06	37	62	4	SM00204
Domain	TGF-b_C	TGFB2 GDF2 MSTN GDF11	6.70e-06	37	62	4	IPR001839
Domain	TGF_BETA_2	TGFB2 GDF2 MSTN GDF11	6.70e-06	37	62	4	PS51362
Domain	TGF_beta	TGFB2 GDF2 MSTN GDF11	6.70e-06	37	62	4	PF00019
Domain	TGF_BETA_1	TGFB2 GDF2 MSTN GDF11	6.70e-06	37	62	4	PS00250
Domain	NtCtMGAM_N	SI MGAM2	6.48e-05	4	62	2	PF16863
Domain	Gal_mutarotase_N	SI MGAM2	6.48e-05	4	62	2	IPR031727
Domain	-	TGFB2 GDF2 MSTN GDF11	7.21e-05	67	62	4	2.10.90.10
Domain	Cystine-knot_cytokine	TGFB2 GDF2 MSTN GDF11	7.21e-05	67	62	4	IPR029034
Domain	Glyco_hydro_31_AS	SI MGAM2	1.61e-04	6	62	2	IPR030458
Domain	Glyco_hydro_31	SI MGAM2	2.25e-04	7	62	2	IPR000322
Domain	Glyco_hydro_47	MAN1A1 MAN1C1	2.25e-04	7	62	2	PF01532
Domain	-	MAN1A1 MAN1C1	2.25e-04	7	62	2	1.50.10.50
Domain	Glyco_hydro_31	SI MGAM2	2.25e-04	7	62	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	SI MGAM2	2.25e-04	7	62	2	PS00129
Domain	Trefoil	SI MGAM2	3.00e-04	8	62	2	PF00088
Domain	Glyco_hydro_47	MAN1A1 MAN1C1	3.00e-04	8	62	2	IPR001382
Domain	P_TREFOIL_2	SI MGAM2	3.85e-04	9	62	2	PS51448
Domain	PD	SI MGAM2	3.85e-04	9	62	2	SM00018
Domain	-	SI MGAM2	5.85e-04	11	62	2	4.10.110.10
Domain	P_trefoil_dom	SI MGAM2	7.00e-04	12	62	2	IPR000519
Domain	Gal_mutarotase_SF_dom	SI MGAM2	1.43e-03	17	62	2	IPR011013
Domain	LRR_8	CNOT6 LRRC8E LRRC8C LRRC8A	2.50e-03	171	62	4	PF13855
Domain	Leu-rich_rpt_typical-subtyp	CNOT6 LRRC8E LRRC8C LRRC8A	2.84e-03	177	62	4	IPR003591
Domain	LRR_TYP	CNOT6 LRRC8E LRRC8C LRRC8A	2.84e-03	177	62	4	SM00369
Domain	LRR	CNOT6 LRRC8E LRRC8C LRRC8A	4.46e-03	201	62	4	PS51450
Domain	LRR_1	CNOT6 LRRC8E LRRC8C LRRC8A	6.03e-03	219	62	4	PF00560
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	LRRC8E LRRC8C LRRC8A	1.35e-04	25	57	3	MM15172
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	LRRC8E LRRC8C LRRC8A	1.53e-04	26	57	3	M27424
Pathway	REACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI	MAN1A1 MAN1C1	1.59e-04	5	57	2	M27954
Pathway	REACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI	MAN1A1 MAN1C1	1.59e-04	5	57	2	MM15670
Pathway	REACTOME_ACYL_CHAIN_REMODELING_OF_DAG_AND_TAG	AWAT2 DGAT2L6	3.33e-04	7	57	2	MM14579
Pathway	REACTOME_ACYL_CHAIN_REMODELING_OF_DAG_AND_TAG	AWAT2 DGAT2L6	3.33e-04	7	57	2	M26959
Pubmed	LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.	LRRC8E LRRC8C LRRC8A	2.61e-08	4	66	3	26824658
Pubmed	LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.	LRRC8E LRRC8C LRRC8A	2.61e-08	4	66	3	33171122
Pubmed	Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy.	LRRC8E LRRC8C LRRC8A	6.51e-08	5	66	3	35777784
Pubmed	LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins.	LRRC8E LRRC8C LRRC8A	6.51e-08	5	66	3	15094057
Pubmed	Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.	LRRC8E LRRC8C LRRC8A	6.51e-08	5	66	3	24790029
Pubmed	Synthesis of neutral ether lipid monoalkyl-diacylglycerol by lipid acyltransferases.	MOGAT2 AWAT2 DGAT2L6	1.30e-07	6	66	3	28420705
Pubmed	Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals.	MOGAT2 AWAT2 DGAT2L6	3.63e-07	8	66	3	14970677
Pubmed	Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.	LRRC8E LRRC8C LRRC8A	1.42e-06	12	66	3	32277911
Pubmed	GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone.	MSTN GDF11	3.55e-06	2	66	2	32071240
Pubmed	The Growth Differentiation Factor 11 (GDF11) and Myostatin (MSTN) in tissue specific aging.	MSTN GDF11	3.55e-06	2	66	2	28472635
Pubmed	Relationship between serum level of growth differentiation factors 8, 11 and bone mineral density in girls with anorexia nervosa.	MSTN GDF11	3.55e-06	2	66	2	30281844
Pubmed	Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.	MSTN GDF11	3.55e-06	2	66	2	26489925
Pubmed	Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.	MSTN GDF11	3.55e-06	2	66	2	36631218
Pubmed	Induction of inducible nitric oxide synthase by lipopolysaccharide/interferon gamma and sepsis down-regulates 5-lipoxygenase metabolism in murine alveolar macrophages.	NOS2 ALOX5	3.55e-06	2	66	2	15371096
Pubmed	Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.	MSTN GDF11	3.55e-06	2	66	2	27304512
Pubmed	Reduced Circulating GDF11 Is Unlikely Responsible for Age-Dependent Changes in Mouse Heart, Muscle, and Brain.	MSTN GDF11	3.55e-06	2	66	2	26372181
Pubmed	Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.	MSTN GDF11	3.55e-06	2	66	2	27034275
Pubmed	LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses.	LRRC8E LRRC8A	3.55e-06	2	66	2	33139539
Pubmed	Supraphysiological levels of GDF11 induce striated muscle atrophy.	MSTN GDF11	3.55e-06	2	66	2	28270449
Pubmed	Structure of a volume-regulated anion channel of the LRRC8 family.	LRRC8C LRRC8A	3.55e-06	2	66	2	29769723
Pubmed	Comparative genomics and proteomics of vertebrate diacylglycerol acyltransferase (DGAT), acyl CoA wax alcohol acyltransferase (AWAT) and monoacylglycerol acyltransferase (MGAT).	AWAT2 DGAT2L6	3.55e-06	2	66	2	20374941
Pubmed	Redundancy of myostatin and growth/differentiation factor 11 function.	MSTN GDF11	3.55e-06	2	66	2	19298661
Pubmed	Structure of a volume-regulated heteromeric LRRC8A/C channel.	LRRC8C LRRC8A	3.55e-06	2	66	2	36522427
Pubmed	Myostatin and the control of skeletal muscle mass.	MSTN GDF11	3.55e-06	2	66	2	10508689
Pubmed	TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.	TGFB2 GDF2 MSTN GDF11	3.75e-06	55	66	4	15342483
Pubmed	Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis.	MAN1A1 MAN1C1	1.06e-05	3	66	2	10915796
Pubmed	Crystal structure of the WFIKKN2 follistatin domain reveals insight into how it inhibits growth differentiation factor 8 (GDF8) and GDF11.	MSTN GDF11	1.06e-05	3	66	2	30814254
Pubmed	Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex.	MAN1A1 MAN1C1	1.06e-05	3	66	2	2406237
Pubmed	The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men.	MSTN GDF11	1.06e-05	3	66	2	32035222
Pubmed	Structural basis for potency differences between GDF8 and GDF11.	MSTN GDF11	1.06e-05	3	66	2	28257634
Pubmed	Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men.	MSTN GDF11	1.06e-05	3	66	2	30165829
Pubmed	The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.	TGFB2 GDF2 GDF11	1.64e-05	26	66	3	31311865
Pubmed	Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily.	AWAT2 DGAT2L6	2.12e-05	4	66	2	15671038
Pubmed	Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases.	MAN1A1 MAN1C1	2.12e-05	4	66	2	17727818
Pubmed	Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren.	NOS2 G6PD	2.12e-05	4	66	2	12641410
Pubmed	Association of TNF-Alpha, MBL2, NOS2, and G6PD with Malaria Outcomes in People in Southern Ghana.	NOS2 G6PD	2.12e-05	4	66	2	35291755
Pubmed	Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development.	MSTN GDF11	2.12e-05	4	66	2	17878677
Pubmed	Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.	MSTN GDF11	2.12e-05	4	66	2	18596030
Pubmed	Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin.	MSTN GDF11	2.12e-05	4	66	2	18535106
Pubmed	Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.	LRRC8E LRRC8A	2.12e-05	4	66	2	28193731
Pubmed	Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ.	MSTN GDF11	3.53e-05	5	66	2	27148972
Pubmed	Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.	MAN1A1 MAN1C1 B3GALT5	4.84e-05	37	66	3	2541446
Pubmed	Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport.	MAN1A1 MAN1C1 B3GALT5	4.84e-05	37	66	3	2542563
Pubmed	Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis.	MAN1A1 MAN1C1 B3GALT5	5.25e-05	38	66	3	2829950
Pubmed	Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1.	MAN1A1 MAN1C1 B3GALT5	5.25e-05	38	66	3	2187500
Pubmed	BMP-11 and myostatin support undifferentiated growth of human embryonic stem cells in feeder-free cultures.	MSTN GDF11	5.29e-05	6	66	2	19751112
Pubmed	Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis.	CCR1 ALOX5	7.40e-05	7	66	2	28529998
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	UNC13B SLC8B1 SLC4A8 SGMS1 SDHAF2 LMO7	7.50e-05	371	66	6	15747579
Pubmed	Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.	MAN1A1 MAN1C1 B3GALT5	9.35e-05	46	66	3	2649653
Pubmed	Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation.	MAN1A1 MAN1C1	9.86e-05	8	66	2	17121831
Pubmed	Autoregulation of neurogenesis by GDF11.	MSTN GDF11	9.86e-05	8	66	2	12546816
Pubmed	A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea.	MSTN GDF11	9.86e-05	8	66	2	31187730
Pubmed	A large-scale candidate gene association study of age at menarche and age at natural menopause.	TGFB2 GDF2 MSTN GDF11 CHRNB1	1.80e-04	275	66	5	20734064
Pubmed	Defining the membrane proteome of NK cells.	CNOT6 LRRC8C MAN1A1 SGMS1 LPCAT3 UBR4 LRRC8A LMBRD2 G6PD	3.49e-04	1168	66	9	19946888
Pubmed	Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.	MSTN GDF11	3.67e-04	15	66	2	24019467
Pubmed	Infectivities of human and other primate lentiviruses are activated by desialylation of the virion surface.	MAN1A1 MAN1C1	3.67e-04	15	66	2	8892864
Pubmed	Developmental changes in extracellular matrix messenger RNAs in the mouse placenta during the second half of pregnancy: possible factors involved in the regulation of placental extracellular matrix expression.	TGFB2 MSTN	4.18e-04	16	66	2	17881772
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	TGFB2 LRRC8C MAN1A1 LPCAT3 LRRC8A LMBRD2 USP15 G6PD IGSF3	4.28e-04	1201	66	9	35696571
Pubmed	Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.	MAN1A1 MAN1C1	4.74e-04	17	66	2	2355006
Pubmed	Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.	NOS2 G6PD	5.94e-04	19	66	2	20459687
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	UNC13B LMO7 UBR4 HTATSF1 ATP10A	6.23e-04	361	66	5	26167880
Pubmed	The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation.	TGFB2 SI	6.59e-04	20	66	2	9203584
Pubmed	CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.	SLC14A2 ZAP70	6.59e-04	20	66	2	23620790
Pubmed	Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin.	MAN1A1 MAN1C1	6.59e-04	20	66	2	12560567
Pubmed	Analyses of associations with asthma in four asthma population samples from Canada and Australia.	PLA2G7 NOS2 ALOX5	7.27e-04	92	66	3	19247692
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	LMO7 HTATSF1 LMBRD2 PLK1 USP15	7.67e-04	378	66	5	34315543
Pubmed	Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.	MAN1A1 MAN1C1	7.99e-04	22	66	2	8673525
Pubmed	Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.	MAN1A1 MAN1C1	7.99e-04	22	66	2	9109416
Pubmed	Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum.	MAN1A1 MAN1C1	7.99e-04	22	66	2	11530211
Pubmed	Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function.	MAN1A1 MAN1C1	8.75e-04	23	66	2	1736542
Pubmed	Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.	MAN1A1 MAN1C1	8.75e-04	23	66	2	8093218
Pubmed	Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins.	MAN1A1 MAN1C1	8.75e-04	23	66	2	3099781
Pubmed	Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.	MAN1A1 MAN1C1	8.75e-04	23	66	2	3264072
Pubmed	OTUB1 modulates c-IAP1 stability to regulate signalling pathways.	UBR4 USP15	9.53e-04	24	66	2	23524849
Pubmed	Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.	MAN1A1 MAN1C1	1.03e-03	25	66	2	2283726
Pubmed	The DNA sequence of the human X chromosome.	CENPI HTATSF1 SMS G6PD DGAT2L6	1.07e-03	407	66	5	15772651
Pubmed	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	MAN1A1 MAN1C1	1.12e-03	26	66	2	8218172
Pubmed	Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.	SGMS1 CERS3	1.21e-03	27	66	2	23096701
Pubmed	Conditionals by inversion provide a universal method for the generation of conditional alleles.	MSTN GDF11	1.21e-03	27	66	2	23918385
Pubmed	Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.	LPCAT3 SI	1.21e-03	27	66	2	28167773
Pubmed	Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.	SGMS1 CERS3	1.21e-03	27	66	2	25269881
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	PLA2G7 NOS2 G6PD TGS1	1.32e-03	250	66	4	18660489
Pubmed	Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.	CCR1 ALOX5	1.39e-03	29	66	2	23708969
Pubmed	Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.	TGFB2 MSTN GDF11	1.45e-03	117	66	3	22682244
Pubmed	Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.	LMO7 PLK1	1.70e-03	32	66	2	31815296
Cytoband	10q11.2	SGMS1 ALOX5	1.83e-04	14	66	2	10q11.2
Cytoband	2q32.2	MSTN NEMP2	2.11e-04	15	66	2	2q32.2
Cytoband	Xq13.1	AWAT2 DGAT2L6	2.20e-03	48	66	2	Xq13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr10q11	SGMS1 GDF2 ALOX5	2.56e-03	188	66	3	chr10q11
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	FBXO6 AADACL4 UTS2 MAN1C1 UBR4	3.00e-03	681	66	5	chr1p36
GeneFamily	Volume regulated anion channel subunits	LRRC8E LRRC8C LRRC8A	1.75e-07	5	48	3	1158
GeneFamily	Diacylglycerol O-acyltransferase 2 family	MOGAT2 AWAT2 DGAT2L6	9.74e-07	8	48	3	1235
GeneFamily	Mannosidases alpha class 1	MAN1A1 MAN1C1	4.13e-05	4	48	2	1193
Coexpression	GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP	LRRC8E NAT8B PHF20L1 LMO7 TCL1A MSTN	8.47e-06	196	64	6	M3239
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NAT8B MOGAT2 TMEM95 NOS2	4.46e-06	75	65	4	3dac715d3610f3bfa6e65e607562d6560462749e
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NAT8B MOGAT2 TMEM95 NOS2	4.46e-06	75	65	4	8a0568fca07cf5d1016a04bcc3ba365dd5e53f7a
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NAT8B MOGAT2 TMEM95 NOS2	4.46e-06	75	65	4	fc508ffa30ec364949b82b8271b8dc4e67b6a416
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NAT8B MOGAT2 TMEM95 NOS2	4.46e-06	75	65	4	324d34ae723a462052074f6a2e4f5d21c4c4c00d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 MTR B3GALT5 SLC14A2 TGS1	9.48e-06	194	65	5	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 MTR B3GALT5 SLC14A2 TGS1	9.48e-06	194	65	5	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	LRRC8E NAT8B TTLL8 SLC14A2	2.60e-05	117	65	4	91936a3ffbfa29024ced9d01df962b4ccfaf8966
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	LRRC8E NAT8B TTLL8 SLC14A2	2.60e-05	117	65	4	e33ec9044541d2ef53f6633891238559b01b7957
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	LRRC8E NAT8B TTLL8 SLC14A2	2.60e-05	117	65	4	454efceabe739cdf293f81c8a938811f12321a47
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL\|Hippocampus / BrainAtlas - Mouse McCarroll V32	LRRC8E NAT8B TTLL8 SLC14A2	2.60e-05	117	65	4	409b3ab16786bced8c9bc9c0e89b0078402f365a
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLA2G7 CCR1 G6PD ALOX5	6.01e-05	145	65	4	ab0e254a8d01021619853a6c175f620ccef217d8
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLA2G7 CCR1 G6PD ALOX5	6.01e-05	145	65	4	2beb4ea3838796c580076ab7769de877a3a0552c
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	AADACL4 MOGAT2 AWAT2 DGAT2L6	6.18e-05	146	65	4	522c32103c24fc26836bb5b642083904682d9292
ToppCell	facs-Trachea-nan-24m-Myeloid-granulocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 B3GALT5 CCR1 ALOX5	7.04e-05	151	65	4	26fd55efb647c41436416d45952ee97b050e632c
ToppCell	facs-Trachea-24m-Hematologic-myeloid-granulocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2G7 B3GALT5 CCR1 ALOX5	8.19e-05	157	65	4	188d2f85babcd4eefe20e7a392d851b2e1185bab
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF527 UTS2 LRRC8A HTATSF1	8.39e-05	158	65	4	a38345ffc5a7576ce99212bcbd620864a19de1fc
ToppCell	facs-Lung-nan-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 PRPH2 CCR1 ALOX5	8.60e-05	159	65	4	836c4b5f9a714ffb5a449087ebefdbb37dd3a2a9
ToppCell	facs-Lung-nan-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 PRPH2 CCR1 ALOX5	8.60e-05	159	65	4	a6742ba2216427409173aec4e05a537d7fde226c
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC8E LRRC8A B3GALT5 ALOX5	9.24e-05	162	65	4	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8B1 MOGAT2 PLK1 ALOX5	9.69e-05	164	65	4	2a230ea066decb798a0e6f2b96c7608c8e608031
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8B1 MOGAT2 PLK1 ALOX5	9.69e-05	164	65	4	d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 CCR1 G6PD ALOX5	9.69e-05	164	65	4	45a6d809d92fd4eee906da3c812282bacffc9f2f
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 CCR1 G6PD ALOX5	9.69e-05	164	65	4	aa4358311fc767c292897e3328309d1bcda392d4
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLA2G7 MAN1A1 CCR1 ALOX5	9.92e-05	165	65	4	47e716ce8dc283d406352c1909e09362fcb9e3a3
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLA2G7 MAN1A1 CCR1 ALOX5	9.92e-05	165	65	4	fe2135fdacf3807eb4b5ea5e790febfb8cd54335
ToppCell	droplet-Spleen-nan-24m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 CCR1 G6PD ALOX5	9.92e-05	165	65	4	3cdb921f5b9facf04f81995d5641ac14ef3dbb6f
ToppCell	facs-Trachea-nan-18m-Myeloid-granulocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 B3GALT5 CCR1 ALOX5	1.02e-04	166	65	4	7f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCell	mild-Lymphocytic-CD4_T_cells_3\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	LRRC8C SGMS1 UTS2 USP15	1.02e-04	166	65	4	f8f8423423d72f0ea0266b59126abb27beb23094
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 CCR1 G6PD ALOX5	1.06e-04	168	65	4	c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCell	Immune_cells-Neutrophils\|Immune_cells / Lineage and Cell class	MOGAT2 CCR1 G6PD ALOX5	1.06e-04	168	65	4	3539f802fe0143da1462df0618f78f9f15143f71
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2G7 FBXO6 CCR1 ALOX5	1.09e-04	169	65	4	c3d410a5e98000ba872141b62e17ef4ed3d1a8eb
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 PLK1 G6PD ALOX5	1.14e-04	171	65	4	95e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 PLK1 G6PD ALOX5	1.14e-04	171	65	4	36657e277aad75c4f157c1726c48e09b5836cf37
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 CCR1 G6PD ALOX5	1.19e-04	173	65	4	0f9784b30c81a4a4940e0623cec60d596e9985d2
ToppCell	FLU-Healthy-3\|FLU / Virus stimulation, Condition and Cluster	FBXO6 LMO7 CENPI CCR1	1.19e-04	173	65	4	32b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCell	FLU-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	FBXO6 LMO7 CENPI CCR1	1.19e-04	173	65	4	26e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 CCR1 G6PD ALOX5	1.19e-04	173	65	4	60f79e0698a7cf7516690fb20f1b82ee46547699
ToppCell	droplet-Marrow-nan-18m-Hematologic-proerythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 CCR1 NOS2 ALOX5	1.19e-04	173	65	4	03cee3d24bc433e91a867ce951589de64a0538af
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 CCR1 G6PD ALOX5	1.30e-04	177	65	4	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 PLK1 G6PD ALOX5	1.30e-04	177	65	4	b41e975e8368e2618b015be095efe8c0e001c78b
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 PLK1 G6PD ALOX5	1.30e-04	177	65	4	15d1de38e4f1a0d4a786d83ee92240f44bdff006
ToppCell	droplet-Marrow-nan-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 CCR1 NOS2 ALOX5	1.30e-04	177	65	4	5d70fe2b0592362d664b3b4c84eb450ec2335957
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 CCR1 G6PD ALOX5	1.30e-04	177	65	4	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	droplet-Marrow-nan-18m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 CCR1 NOS2 ALOX5	1.30e-04	177	65	4	48bcf603ec9593eedd81f3831cf9fde89fad368f
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 PLK1 G6PD ALOX5	1.33e-04	178	65	4	15a99080e9f669572ab6d82934f324e6714846c1
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOGAT2 PLK1 G6PD ALOX5	1.33e-04	178	65	4	200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1C1 CENPI ALOX5 IGSF3	1.42e-04	181	65	4	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1C1 CENPI ALOX5 IGSF3	1.42e-04	181	65	4	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1C1 CENPI ALOX5 IGSF3	1.42e-04	181	65	4	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	droplet-Marrow-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8B1 MOGAT2 G6PD ALOX5	1.54e-04	185	65	4	3dcafbd02b65a2befbb6e6288cb2591e721cddb6
Drug	1-acetyl-sn-glycero-3-phosphocholine	CNOT6 PLA2G7 SGMS1 UTS2 LPCAT3 CCR1 NOS2 ALOX5	1.71e-06	305	62	8	CID005311264
Drug	thymoquinone	MTR PLK1 NOS2 ALOX5	4.23e-06	40	62	4	CID000010281
Disease	vertebral hypersegmentation and orofacial anomalies (implicated_via_orthology)	MSTN GDF11	4.34e-06	2	62	2	DOID:0070418 (implicated_via_orthology)
Disease	pulmonary edema (biomarker_via_orthology)	SGMS1 NOS2	2.60e-05	4	62	2	DOID:11396 (biomarker_via_orthology)
Disease	pulmonary edema (implicated_via_orthology)	SGMS1 ALOX5	4.33e-05	5	62	2	DOID:11396 (implicated_via_orthology)
Disease	Endotoxemia	NOS2 ALOX5	1.21e-04	8	62	2	C0376618
Disease	anterior uveitis (biomarker_via_orthology)	CCR1 NOS2	1.55e-04	9	62	2	DOID:1407 (biomarker_via_orthology)
Disease	uremia (biomarker_via_orthology)	MSTN NOS2	1.93e-04	10	62	2	DOID:4676 (biomarker_via_orthology)
Disease	pleurisy (implicated_via_orthology)	NOS2 ALOX5	3.34e-04	13	62	2	DOID:10247 (implicated_via_orthology)
Disease	myocardial infarction (biomarker_via_orthology)	TGFB2 UTS2 NOS2 G6PD	3.64e-04	160	62	4	DOID:5844 (biomarker_via_orthology)
Disease	coronary artery disease (is_marker_for)	PLA2G7 CCR1 NOS2	3.85e-04	67	62	3	DOID:3393 (is_marker_for)
Disease	hepatic encephalopathy (biomarker_via_orthology)	NOS2 G6PD	4.48e-04	15	62	2	DOID:13413 (biomarker_via_orthology)
Disease	–	NOS2 G6PD	5.11e-04	16	62	2	611162
Disease	Malaria, susceptibility to	NOS2 G6PD	5.11e-04	16	62	2	cv:C1970028
Disease	Asthma	PLA2G7 NOS2 ALOX5	6.47e-04	80	62	3	C0004096
Disease	pulmonary hypertension (biomarker_via_orthology)	UTS2 NOS2 ALOX5	6.47e-04	80	62	3	DOID:6432 (biomarker_via_orthology)
Disease	carotid artery disease (is_marker_for)	PLA2G7 UTS2	7.26e-04	19	62	2	DOID:3407 (is_marker_for)
Disease	Malaria	NOS2 G6PD	8.05e-04	20	62	2	C0024530
Disease	Ureteral obstruction	TGFB2 NOS2	1.16e-03	24	62	2	C0041956
Disease	malaria (is_implicated_in)	NOS2 G6PD	1.16e-03	24	62	2	DOID:12365 (is_implicated_in)
Disease	Colitis	NOS2 ALOX5	1.26e-03	25	62	2	C0009319
Disease	pancreatic cancer (is_marker_for)	B3GALT5 NOS2 ALOX5	1.27e-03	101	62	3	DOID:1793 (is_marker_for)
Disease	obstructive sleep apnea (is_marker_for)	PLA2G7 NOS2	1.70e-03	29	62	2	DOID:0050848 (is_marker_for)
Disease	Drug-Induced Stevens Johnson Syndrome	FBXO6 NOS2	1.70e-03	29	62	2	C1274933
Disease	1,5 anhydroglucitol measurement	SI MGAM2	1.70e-03	29	62	2	EFO_0008009
Disease	Toxic Epidermal Necrolysis	FBXO6 NOS2	1.70e-03	29	62	2	C0014518
Disease	Mycoplasma-Induced Stevens-Johnson Syndrome	FBXO6 NOS2	1.70e-03	29	62	2	C3658301
Disease	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	FBXO6 NOS2	1.70e-03	29	62	2	C3658302
Disease	pulmonary hypertension (is_implicated_in)	NOS2 ALOX5	1.82e-03	30	62	2	DOID:6432 (is_implicated_in)
Disease	Stevens-Johnson Syndrome	FBXO6 NOS2	1.82e-03	30	62	2	C0038325
Disease	IgA glomerulonephritis (is_implicated_in)	PLA2G7 MTR	1.82e-03	30	62	2	DOID:2986 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KLQSFYPWEWGEKRI	ERVK-8	306	Q902F8
VYYDTLWKPVVELWR	CATSPERD	576	Q86XM0
KVYLDLEWTDYRLSW	CHRNB1	76	P11230
SKWFVSKSEYPWDRY	B3GALT5	196	Q9Y2C3
DVWRKYEKWLSPDNI	AADACL4	276	Q5VUY2
KDWDQPVADWKIFYF	FBXO6	66	Q9NRD1
WIWRYQEKKSLFYVP	ATP10A	331	O60312
KKIYPTIWWLFRDGL	G6PD	46	P11413
WDSWIIAPKEYEAYE	GDF2	341	Q9UK05
AYRILKPWWDVFTDY	LRRC8A	16	Q8IWT6
YEWFRELELKWYALP	NOS2	336	P35228
AAWWKKEIEELYANP	MGAM2	1346	Q2M2H8
LMEDLKWLWYENRIY	NEMP2	226	A6NFY4
NWKRIKRETYKPWYK	LMO7	431	Q8WWI1
LFTWDKWLKVYKSIY	LPCAT3	441	Q6P1A2
AFKVLKPWWDVLAEY	LRRC8E	16	Q6NSJ5
LEWLALIDWDDDKYY	IGHV2-70	66	P01814
LEWLALIYWDDDKRY	IGHV2-5	66	P01817
DRLDTLWIPNKEYFW	PLA2G7	91	Q13093
TDTPYEWDLDKKAWF	HTATSF1	46	O43719
VLYAAWWYLDRDKPR	MOGAT2	51	Q3SYC2
RYWASVEEYIPKWEQ	C3orf14	86	Q9HBI5
AFLYDKPWLYDLWEV	CERS3	151	Q8IU89
EWLLSPNYAWYKLAE	IGSF3	786	O75054
WKQWREFLVKYSFLP	BFAR	326	Q9NZS9
WRLWKHYSDYFPLKL	AWAT2	76	Q6E213
TLPFWIDYKLKDDWV	CCR1	86	P32246
WTLWKYFRNYFPVKL	DGAT2L6	76	Q6ZPD8
GWDWIIAPKRYKANY	GDF11	326	O95390
YREWGWEVVLALEKY	MAN1C1	541	Q9NR34
DPKYRKWAWEAVEAL	MAN1A1	561	P33908
IRGKKWSWYLDYLFS	CENPI	711	Q92674
FEKWWDKSRTVPFYL	SLC38A9	281	Q8NBW4
PSWALNWDYRKKAII	CNOT6	211	Q9ULM6
LVYFQRYVWWKKSLE	UPF2	946	Q9HAU5
PLDYMKWRRKSAYWK	SLC8B1	311	Q6J4K2
GQRWSAKYRYDKEWL	PHF20L1	731	A8MW92
WDIYYWATEAKPAPE	SDHAF2	116	Q9NX18
IWKPYKKRETPDCFW	UTS2	106	O95399
PQLKNETIWYLKYHW	ATP6V0E1	66	O15342
YLELWVFYTVWKKAK	SMS	351	P52788
WLNDDWYLKYITLKT	ALOX5	76	P09917
PSDAKYDWLLAKIWV	ALOX5	341	P09917
YWECLLRPWFYKILA	LMBRD2	376	Q68DH5
EAFGWDWIIAPKRYK	MSTN	291	O14793
SLRVWEWDIPVDFKY	CDC40	441	O60508
DYIDWKPFFDVWQLR	MTR	971	Q99707
IWYDYESGAKRPWRK	SI	761	P14410
VLDIKRKAPWYWSDY	SLC4A8	456	Q2Y0W8
RKAPWYWSDYRDALS	SLC4A8	461	Q2Y0W8
DRLWAWEKFVYLDEK	TCL1A	16	P56279
RYLQPREWKKLAYSW	ANKDD1A	421	Q495B1
SYWSWLRKTKLPEYT	TMEM95	86	Q3KNT9
PLYIDFKRDLGWKWI	TGFB2	321	P61812
WIYKWEDRPDFLTVE	ZAP70	576	P43403
DWNPLTIWFYKESYL	TTLL8	416	A6PVC2
YARWKPWLKPYLAIC	PRPH2	91	P23942
YLVDSRWFKQWKKYV	USP15	31	Q9Y4E8
YWSPKKVADWLLENA	SGMS1	6	Q86VZ5
YMKVYKEEWIPDWRR	POLR3G	91	O15318
FDIPEEEARYWTYKW	UNC13B	131	O14795
KLEITEKWEKYWNEY	TGS1	191	Q96RS0
YLTEKYVWRWKQFLS	UBR4	4096	Q5T4S7
FSEKLDYYWWLLFPV	SLC14A2	196	Q15849
EWKSLDPVQKALYWD	ZNF836	21	Q6ZNA1
EEWEWLKPSQKDLYR	ZNF527	26	Q8NB42
IPIFWVSKWVDYSDK	PLK1	406	P53350
AFRVLKPWWDVFTDY	LRRC8C	16	Q8TDW0
LPALWFLAKKPWTRY	NAT8B	71	Q9UHF3