Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	PDE2A PDE10A	1.11e-04	3	122	2	GO:0004118
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE2A PDE1B PDE10A	3.15e-04	22	122	3	GO:0004115
GeneOntologyMolecularFunction	3',5'-cyclic-GMP phosphodiesterase activity	PDE2A PDE1B PDE10A	4.10e-04	24	122	3	GO:0047555
GeneOntologyMolecularFunction	3',5'-cyclic-nucleotide phosphodiesterase activity	PDE2A PDE1B PDE10A	4.64e-04	25	122	3	GO:0004114
GeneOntologyMolecularFunction	cyclic-nucleotide phosphodiesterase activity	PDE2A PDE1B PDE10A	5.85e-04	27	122	3	GO:0004112
GeneOntologyCellularComponent	somatodendritic compartment	GPHN PDE2A HTR2C PDE1B COPA MAP1B MYO5A MYO5B SLC31A1 NTRK1 ESR2 DVL1 SPG11 PDE10A PTK7 CSF1R GRK3 VPS13A DYNC1H1	8.03e-05	1228	121	19	GO:0036477
GeneOntologyCellularComponent	neuronal cell body	GPHN PDE1B COPA MAP1B MYO5A MYO5B SLC31A1 NTRK1 ESR2 DVL1 PDE10A PTK7 CSF1R VPS13A DYNC1H1	9.71e-05	835	121	15	GO:0043025
GeneOntologyCellularComponent	cell body	GPHN PDE1B COPA MAP1B MYO5A MYO5B SLC31A1 NTRK1 ESR2 DVL1 PDE10A PTK7 CSF1R VPS13A DYNC1H1	3.09e-04	929	121	15	GO:0044297
GeneOntologyCellularComponent	recycling endosome	ANK2 MYO5A MYO5B SLC31A1 NTRK1 ATP11B NISCH	3.14e-04	222	121	7	GO:0055037
GeneOntologyCellularComponent	hippocampal mossy fiber	PDE2A MAP1B	6.85e-04	7	121	2	GO:0097457
Domain	DUF1088	NBEA LRBA	4.16e-05	2	121	2	IPR010508
Domain	DVL-1	DVL1P1 DVL1	4.16e-05	2	121	2	IPR008340
Domain	DUF1088	NBEA LRBA	4.16e-05	2	121	2	PF06469
Domain	PDEase	PDE2A PDE1B PDE10A	2.38e-04	19	121	3	IPR023088
Domain	Dishevelled	DVL1P1 DVL1	2.48e-04	4	121	2	PF02377
Domain	Dishevelled_fam	DVL1P1 DVL1	2.48e-04	4	121	2	IPR008339
Domain	Dishevelled_protein_dom	DVL1P1 DVL1	2.48e-04	4	121	2	IPR003351
Domain	PDEase_I	PDE2A PDE1B PDE10A	3.24e-04	21	121	3	PF00233
Domain	PDEASE_I	PDE2A PDE1B PDE10A	3.24e-04	21	121	3	PS00126
Domain	PDEase_CS	PDE2A PDE1B PDE10A	3.24e-04	21	121	3	IPR023174
Domain	DEP	DVL1P1 DVL1 DEPDC1	3.73e-04	22	121	3	PF00610
Domain	DEP	DVL1P1 DVL1 DEPDC1	3.73e-04	22	121	3	PS50186
Domain	-	PDE2A PDE1B PDE10A	3.73e-04	22	121	3	1.10.1300.10
Domain	DEP	DVL1P1 DVL1 DEPDC1	3.73e-04	22	121	3	SM00049
Domain	Leu-rich_rpt	NLRP11 NTRK1 LGR5 RSU1 NLRP14 LRFN5 NISCH DNAAF1	3.88e-04	271	121	8	IPR001611
Domain	Myosin_S1_N	MYO5A MYO5B	4.11e-04	5	121	2	IPR008989
Domain	DUF4704	NBEA LRBA	4.11e-04	5	121	2	IPR031570
Domain	DUF4704	NBEA LRBA	4.11e-04	5	121	2	PF15787
Domain	DEP_dom	DVL1P1 DVL1 DEPDC1	4.27e-04	23	121	3	IPR000591
Domain	PDEase_catalytic_dom	PDE2A PDE1B PDE10A	4.27e-04	23	121	3	IPR002073
Domain	HD/PDEase_dom	PDE2A PDE1B PDE10A	4.86e-04	24	121	3	IPR003607
Domain	HDc	PDE2A PDE1B PDE10A	4.86e-04	24	121	3	SM00471
Domain	Dilute_dom	MYO5A MYO5B	6.14e-04	6	121	2	IPR002710
Domain	PH_BEACH	NBEA LRBA	6.14e-04	6	121	2	PF14844
Domain	DIL	MYO5A MYO5B	6.14e-04	6	121	2	PF01843
Domain	DILUTE	MYO5A MYO5B	6.14e-04	6	121	2	PS51126
Domain	DIL	MYO5A MYO5B	6.14e-04	6	121	2	SM01132
Domain	ZnF_UBR1	UBR2 UBR4	8.56e-04	7	121	2	SM00396
Domain	ZF_UBR	UBR2 UBR4	8.56e-04	7	121	2	PS51157
Domain	DIX	DVL1P1 DVL1	8.56e-04	7	121	2	PF00778
Domain	zf-UBR	UBR2 UBR4	8.56e-04	7	121	2	PF02207
Domain	GAF	PDE2A PDE10A	8.56e-04	7	121	2	PF01590
Domain	Znf_UBR	UBR2 UBR4	8.56e-04	7	121	2	IPR003126
Domain	DIX	DVL1P1 DVL1	8.56e-04	7	121	2	IPR001158
Domain	DIX	DVL1P1 DVL1	8.56e-04	7	121	2	PS50841
Domain	DAX	DVL1P1 DVL1	8.56e-04	7	121	2	SM00021
Domain	WHTH_DNA-bd_dom	UBR2 DVL1P1 DVL1 DEPDC1 EIF2B2 ASCC3 RPA2	1.02e-03	242	121	7	IPR011991
Domain	GAF	PDE2A PDE10A	1.14e-03	8	121	2	IPR003018
Domain	PH-BEACH_dom	NBEA LRBA	1.14e-03	8	121	2	IPR023362
Domain	-	NBEA LRBA	1.14e-03	8	121	2	2.30.29.40
Domain	PH_BEACH	NBEA LRBA	1.14e-03	8	121	2	PS51783
Domain	GAF	PDE2A PDE10A	1.14e-03	8	121	2	SM00065
Domain	-	NLRP11 NTRK1 LGR5 RSU1 NLRP14 LRFN5 NISCH DNAAF1	1.17e-03	321	121	8	3.80.10.10
Domain	L_dom-like	NLRP11 NTRK1 LGR5 RSU1 NLRP14 LRFN5 NISCH DNAAF1	1.34e-03	328	121	8	IPR032675
Domain	BEACH	NBEA LRBA	1.45e-03	9	121	2	PS50197
Domain	Beach	NBEA LRBA	1.45e-03	9	121	2	PF02138
Domain	-	NBEA LRBA	1.45e-03	9	121	2	1.10.1540.10
Domain	-	PDE2A PDE10A	1.45e-03	9	121	2	3.30.450.40
Domain	Beach	NBEA LRBA	1.45e-03	9	121	2	SM01026
Domain	BEACH_dom	NBEA LRBA	1.45e-03	9	121	2	IPR000409
Domain	GAF_dom-like	PDE2A PDE10A	1.45e-03	9	121	2	IPR029016
Domain	ARM-type_fold	UBR4 NBEA IPO9 NCAPD2 SERAC1 NUP188 LRBA UNC79	1.65e-03	339	121	8	IPR016024
Domain	Myosin_head_motor_dom	MYO5A MYO5B MYO16	1.90e-03	38	121	3	IPR001609
Domain	MYOSIN_MOTOR	MYO5A MYO5B MYO16	1.90e-03	38	121	3	PS51456
Domain	Myosin_head	MYO5A MYO5B MYO16	1.90e-03	38	121	3	PF00063
Domain	MYSc	MYO5A MYO5B MYO16	1.90e-03	38	121	3	SM00242
Domain	RECEPTOR_TYR_KIN_II	NTRK1 PTK7	2.63e-03	12	121	2	PS00239
Domain	Myotubularin-like_Pase_dom	MTMR1 MTM1	3.60e-03	14	121	2	IPR010569
Domain	PPASE_MYOTUBULARIN	MTMR1 MTM1	3.60e-03	14	121	2	PS51339
Domain	Myotubularin_fam	MTMR1 MTM1	3.60e-03	14	121	2	IPR030564
Domain	Myotub-related	MTMR1 MTM1	3.60e-03	14	121	2	PF06602
Domain	GPCR_Rhodpsn_7TM	OR2L8 OR2L3 HTR2C OR2L5 LGR5 OR2L13 TAAR6 NPFFR2 OR2L2 OR10K2 CCR8	4.19e-03	670	121	11	IPR017452
Domain	7tm_1	OR2L8 OR2L3 HTR2C OR2L5 LGR5 OR2L13 TAAR6 NPFFR2 OR2L2 OR10K2 CCR8	4.53e-03	677	121	11	PF00001
Domain	Prot_kinase_dom	CDC42BPG NTRK1 ERN2 STK35 MAP3K6 PTK7 CHUK CSF1R GRK3	4.56e-03	489	121	9	IPR000719
Domain	GRAM	MTMR1 MTM1	4.71e-03	16	121	2	SM00568
Domain	PROTEIN_KINASE_DOM	CDC42BPG NTRK1 ERN2 STK35 MAP3K6 PTK7 CHUK CSF1R GRK3	4.81e-03	493	121	9	PS50011
Domain	G_PROTEIN_RECEP_F1_1	OR2L8 OR2L3 HTR2C OR2L5 LGR5 OR2L13 TAAR6 NPFFR2 OR2L2 OR10K2 CCR8	4.94e-03	685	121	11	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2L8 OR2L3 HTR2C OR2L5 LGR5 OR2L13 TAAR6 NPFFR2 OR2L2 OR10K2 CCR8	5.27e-03	691	121	11	PS50262
Domain	Interferon	IFNW1 IFNE	5.31e-03	17	121	2	PF00143
Domain	INTERFERON_A_B_D	IFNW1 IFNE	5.31e-03	17	121	2	PS00252
Domain	Interferon_alpha/beta/delta	IFNW1 IFNE	5.31e-03	17	121	2	IPR000471
Domain	IFabd	IFNW1 IFNE	5.31e-03	17	121	2	SM00076
Domain	GPCR_Rhodpsn	OR2L8 OR2L3 HTR2C OR2L5 LGR5 OR2L13 TAAR6 NPFFR2 OR2L2 OR10K2 CCR8	5.32e-03	692	121	11	IPR000276
Pathway	REACTOME_CGMP_EFFECTS	PDE2A PDE1B PDE10A	2.73e-05	10	88	3	MM15054
Pathway	REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE	PDE2A PDE1B PDE10A	6.43e-05	13	88	3	MM15015
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A PDE2A KIF26A UBR4 HECTD4 DVL1 MAML1 MED14 BIRC6 EPS15L1 PLEKHM2 ZNF827 TMEM259 NISCH NCAPD2 NUP188 LRBA PLXNA1 DYNC1H1	1.45e-08	1105	124	19	35748872
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AARS1 PDE2A ATP6V0A1 ZNF234 ANK2 COPA MYO5A UBR4 HECTD4 MAGI3 NBEA CHUK EPS15L1 SUPV3L1 NISCH MTM1 ZBTB5 LRBA DYNC1H1	1.54e-07	1285	124	19	35914814
Pubmed	Defining the membrane proteome of NK cells.	AARS1 COPA MYO5A UBR4 ELOVL1 MED14 BIRC6 EPS15L1 IPO9 ATP11B NISCH DHCR7 NCAPD2 NUP188 LRBA ASCC3 ZDHHC13 DYNC1H1	1.85e-07	1168	124	18	19946888
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ANK2 COPA MAP1B ZFYVE16 MTMR1 MAGI3 EPS15L1 DHCR7 NCAPD2 ARHGAP29 LRBA ASCC3 SMCR8 DYNC1H1	2.56e-07	708	124	14	39231216
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	AARS1 ATP6V0A1 COPA UBR4 PTK7 IPO9 TMEM259 NISCH DHCR7 EIF2B2 NCAPD2 NUP188 ASCC3 DYNC1H1 HELLS	1.42e-06	942	124	15	31073040
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	GPHN ZFYVE16 NBEA SPG11 PLEKHM2 NISCH VPS13A LRBA SMCR8 ZDHHC13 PLXNA1	2.06e-06	504	124	11	34432599
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	GPHN UBR2 COPA MAP1B UBR4 MAML1 MTMR1 DEPDC1 CHUK NISCH NCAPD2 RPA2 DYNC1H1 HELLS	2.43e-06	857	124	14	25609649
Pubmed	Chemical characterization of hair melanins in various coat-color mutants of mice.	MYO5A DCT BMP5	3.66e-06	9	124	3	7665913
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	ANK2 COPA ZFYVE16 ELOVL1 NBEA EPS15L1 IPO9 NISCH NCAPD2 LRBA	5.12e-06	449	124	10	31732153
Pubmed	FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.	NTRK1 FRS3 KL	5.21e-06	10	124	3	10629055
Pubmed	Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.	PDE2A PDE1B PDE10A	1.23e-05	13	124	3	8557689
Pubmed	Characterisation of Lu AF33241: A novel, brain-penetrant, dual inhibitor of phosphodiesterase (PDE) 2A and PDE10A.	PDE2A PDE10A	1.26e-05	2	124	2	25941078
Pubmed	Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR.	POSTN CSF1R	1.26e-05	2	124	2	27602954
Pubmed	Molecular genetic analysis of the dilute-short ear (d-se) region of the mouse.	MYO5A BMP5	1.26e-05	2	124	2	3000867
Pubmed	Linkage of Short Ear and Density in the House Mouse.	MYO5A BMP5	1.26e-05	2	124	2	16587226
Pubmed	A Cross-over between the Genes for Short-Ear and Density in the House Mouse.	MYO5A BMP5	1.26e-05	2	124	2	16587426
Pubmed	Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.	DVL1P1 DVL1	1.26e-05	2	124	2	8644734
Pubmed	Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease.	PDE2A PDE10A	1.26e-05	2	124	2	32119913
Pubmed	Loss of heterozygosity at the dilute-short ear (Myo5a-Bmp5) region of the mouse: mitotic recombination or double non-disjunction?	MYO5A BMP5	1.26e-05	2	124	2	10036975
Pubmed	IDENTICAL TWINS IN A MOUSE CROSS.	MYO5A BMP5	1.26e-05	2	124	2	17748600
Pubmed	Myosin Va controls oligodendrocyte morphogenesis and myelination.	MYO5A BMP5	1.26e-05	2	124	2	17942731
Pubmed	Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expression.	IPO9 IFNE	1.26e-05	2	124	2	23851686
Pubmed	Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells.	MTMR1 MTM1	1.26e-05	2	124	2	12217958
Pubmed	Linkage of the Factors for Short-Ear and Density in the House Mouse (MUS MUSCULUS).	MYO5A BMP5	1.26e-05	2	124	2	17246548
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	SETD1A ATP6V0A1 COPA MAP1B MYO5A UBR4 IPO9 ATP11B	1.75e-05	313	124	8	38270169
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 CDC42BPG MAP1B MYO5A SLC31A1 HECTD4 MAGI3 PDE10A RSU1 PTK7 ANKRD44 EPS15L1 GRK3 ATP11B ZNF827 LRBA ZDHHC13	2.25e-05	1489	124	17	28611215
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	AARS1 COPA MAP1B MYO5A POLA1 UBR4 BIRC6 NCAPD2 NUP188 ASCC3 DYNC1H1	2.34e-05	653	124	11	22586326
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	UBR2 COPA MYO5A ZFYVE16 MYO5B MTMR1 NBEA BIRC6 POSTN IPO9 MTM1 VPS13A RPA2 HELLS	2.37e-05	1049	124	14	27880917
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	COPA MAP1B UBR4 BIRC6 IPO9 TMEM259 DHCR7 EIF2B2 NCAPD2 VPS13A NUP188	2.47e-05	657	124	11	36180527
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	GPHN SETD1A MAP1B DVL1 MED14 EPS15L1 NCAPD2 LRBA ASCC3 DYNC1H1	2.89e-05	549	124	10	38280479
Pubmed	Poor replication of candidate genes for major depressive disorder using genome-wide association data.	PDE2A HTR2C ESR2 PDE10A	3.38e-05	51	124	4	20351714
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	AARS1 COPA MAP1B UBR4 BIRC6 IPO9 MTM1 DYNC1H1	3.44e-05	344	124	8	30333137
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	UBR2 SETD1A ZFYVE16 ZBTB5 DYNC1H1	3.68e-05	104	124	5	9205841
Pubmed	The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.	NBEA LRBA	3.77e-05	3	124	2	28814779
Pubmed	Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes.	TRPC1 DCT	3.77e-05	3	124	2	8126111
Pubmed	Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.	MYO5A MYO5B	3.77e-05	3	124	2	28939769
Pubmed	Genetic ablation of a mouse gene expressed specifically in brain.	MYO5A BMP5	3.77e-05	3	124	2	2303033
Pubmed	Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.	MYO5A MYO5B	3.77e-05	3	124	2	24508725
Pubmed	Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.	MYO5A MYO5B	3.77e-05	3	124	2	24339992
Pubmed	Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations.	MYO5A BMP5	3.77e-05	3	124	2	5556347
Pubmed	Expression of Trk A and Src and their interaction with ERβ ligand binding domain show age and sex dependent alteration in mouse brain.	NTRK1 ESR2	3.77e-05	3	124	2	22011838
Pubmed	The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.	MYO5A MYO5B	3.77e-05	3	124	2	16713372
Pubmed	Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity.	TRPC1 KL	3.77e-05	3	124	2	20966350
Pubmed	Genomic organization of a 225-kb region in Xq28 containing the gene for X-linked myotubular myopathy (MTM1) and a related gene (MTMR1).	MTMR1 MTM1	3.77e-05	3	124	2	9828128
Pubmed	Structural insights into functional overlapping and differentiation among myosin V motors.	MYO5A MYO5B	3.77e-05	3	124	2	24097982
Pubmed	LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway.	LGR5 CHUK	3.77e-05	3	124	2	27049829
Pubmed	Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity.	PDE2A PDE10A	3.77e-05	3	124	2	19689430
Pubmed	The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells.	MYO5A BMP5	3.77e-05	3	124	2	7493015
Pubmed	Klotho/fibroblast growth factor 23- and PTH-independent estrogen receptor-α-mediated direct downregulation of NaPi-IIa by estrogen in the mouse kidney.	ESR2 KL	3.77e-05	3	124	2	27194721
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GPHN PDE2A ANK2 PDE1B MYO5A UBR4 HECTD4 NBEA EPS15L1 TMEM259 NISCH UNC79 DYNC1H1	4.19e-05	963	124	13	28671696
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	CDC42BPG THNSL1 HECTD4 PTK7 SUPV3L1 ARHGAP29	5.22e-05	183	124	6	31932471
Pubmed	Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3.	PDE2A PDE1B PDE10A	5.61e-05	21	124	3	27740716
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	GPHN MYO5A UBR4 HECTD4 CHUK EPS15L1 ARHGAP29 ASCC3 TOPORS	5.98e-05	481	124	9	28190767
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GPHN AARS1 COPA POLA1 UBR4 BIRC6 RSU1 CHUK EPS15L1 IPO9 EIF2B2 NCAPD2 NUP188 LRBA RPA2 DYNC1H1	6.24e-05	1455	124	16	22863883
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CDC42BPG POLA1 UBR4 LCA5L MAGI3 NBEA BIRC6 VPS13A CCDC87 NUP188 DYNC1H1	6.87e-05	736	124	11	29676528
Pubmed	Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression.	MYO5A BMP5	7.53e-05	4	124	2	1329656
Pubmed	A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.	UBR2 UBR4	7.53e-05	4	124	2	16055722
Pubmed	Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system.	PDE2A PDE10A	7.53e-05	4	124	2	15938621
Pubmed	Functional redundancy in the myotubularin family.	MTMR1 MTM1	7.53e-05	4	124	2	11846405
Pubmed	cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.	DVL1P1 DVL1	7.53e-05	4	124	2	8817329
Pubmed	Human dishevelled genes constitute a DHR-containing multigene family.	DVL1P1 DVL1	7.53e-05	4	124	2	9192851
Pubmed	The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a.	MYO5A BMP5	7.53e-05	4	124	2	10749990
Pubmed	Mutations in the microtubule-associated protein 1A (Map1a) gene cause Purkinje cell degeneration.	AARS1 MAP1B	7.53e-05	4	124	2	25788676
Pubmed	Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4.	DVL1P1 DVL1	7.53e-05	4	124	2	20639201
Pubmed	Polymorphism and linkage for mannosephosphate isomerase in Mus musculus.	MYO5A BMP5	7.53e-05	4	124	2	4693062
Pubmed	Structural basis of myosin V Rab GTPase-dependent cargo recognition.	MYO5A MYO5B	7.53e-05	4	124	2	24248336
Pubmed	The substrate recognition domains of the N-end rule pathway.	UBR2 UBR4	7.53e-05	4	124	2	19008229
Pubmed	Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatases.	MTMR1 MTM1	7.53e-05	4	124	2	12925573
Pubmed	Alternative splicing in class V myosins determines association with Rab10.	MYO5A MYO5B	7.53e-05	4	124	2	19008234
Pubmed	The structural integrity of ROR alpha isoforms is mutated in staggerer mice: cerebellar coexpression of ROR alpha1 and ROR alpha4.	MYO5A BMP5	7.53e-05	4	124	2	9226375
Pubmed	Differentiation of human monocytes in vitro with granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression.	PDE2A PDE1B	7.53e-05	4	124	2	14687666
Pubmed	SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes.	ANK2 MAP1B	7.53e-05	4	124	2	31277379
Pubmed	Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2.	PTK7 PLXNA1	7.53e-05	4	124	2	14977921
Pubmed	Genes for epilepsy mapped in the mouse.	MYO5A BMP5	7.53e-05	4	124	2	1871601
Pubmed	Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease.	POSTN KL	7.53e-05	4	124	2	22248532
Pubmed	Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.	MAP1B DYNC1H1	7.53e-05	4	124	2	15762842
Pubmed	Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex.	ESR2 MED14	7.53e-05	4	124	2	10770935
Pubmed	Inheritance in the House Mouse, the Linkage Relations of Short-Ear, Hairless, and Naked.	MYO5A BMP5	7.53e-05	4	124	2	17246610
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	ACSL6 PDE2A ATP6V0A1 PDE1B MAP1B MYO5A MYO5B MTMR1 EPS15L1 DYNC1H1	8.08e-05	621	124	10	22794259
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	GPHN ACSL6 AARS1 ANK2 MYO5A DYNC1H1	9.01e-05	202	124	6	33601422
Pubmed	Overview of PDEs and their regulation.	PDE2A PDE1B PDE10A	9.61e-05	25	124	3	17307970
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	COPA POLA1 UBR4 IPO9 NCAPD2 NUP188 LRBA ASCC3 DYNC1H1 HELLS	1.01e-04	638	124	10	33239621
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	UBR4 MAML1 ADAM30 NBEA ZDBF2 IPO9 VPS13A DNAAF1 SMCR8 HELLS	1.01e-04	638	124	10	31182584
Pubmed	Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.	GPHN ATP6V0A1 ANK2 PDE1B MAP1B MYO5A PDE10A DYNC1H1	1.04e-04	403	124	8	30562941
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	MAML1 NBEA BIRC6 EPS15L1 PLEKHM2 DHCR7 VPS13A LRBA SMCR8 DYNC1H1 HELLS	1.11e-04	777	124	11	35844135
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CDC42BPG AARS1 THNSL1 MAP1B ELOVL1 MAP3K6 PTK7 SUPV3L1 NISCH HELLS	1.17e-04	650	124	10	38777146
Pubmed	Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.	GPHN NBEA LRBA	1.22e-04	27	124	3	19723784
Pubmed	HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.	PDE2A PDE1B PDE10A	1.22e-04	27	124	3	11156964
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A KIF26A HECTD4 MAML1 SPG11 ATP11B NCAPD2 ZBTB5 NUP188	1.23e-04	529	124	9	14621295
Pubmed	The Pk-3 gene determines both the heart, M1, and the kidney, M2, pyruvate kinase isozymes in the mouse; and a simple electrophoretic method for separating phosphoglucomutase-3.	MYO5A BMP5	1.25e-04	5	124	2	6241468
Pubmed	BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function.	NBEA LRBA	1.25e-04	5	124	2	12160729
Pubmed	5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.	HTR2C MYO5A	1.25e-04	5	124	2	9165122
Pubmed	A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast.	MTMR1 MTM1	1.25e-04	5	124	2	8640223
Pubmed	Mechanisms of mutation induction in germ cells of the mouse as assessed by the specific locus test.	MYO5A BMP5	1.25e-04	5	124	2	10517996
Pubmed	The position of luxoid in linkage group II of the mouse.	MYO5A BMP5	1.25e-04	5	124	2	13901431
Pubmed	Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.	MYO5A MYO5B NBEA LRBA	1.31e-04	72	124	4	34882091
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZFYVE16 UBR4 DVL1 ZDBF2 BIRC6 PHC3 LRBA ASCC3	1.33e-04	418	124	8	34709266
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	AARS1 ATP6V0A1 COPA POLA1 TRPC1 UBR4 IPO9 SUPV3L1 DHCR7 NCAPD2 NUP188 RPA2 PLXNA1 DYNC1H1 HELLS	1.73e-04	1425	124	15	30948266
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	AARS1 DCT OTOG	1.85e-04	31	124	3	31550482
Pubmed	Autism and Intellectual Disability-Associated KIRREL3 Interacts with Neuronal Proteins MAP1B and MYO16 with Potential Roles in Neurodevelopment.	MAP1B MYO16	1.87e-04	6	124	2	25902260
Interaction	PDGFRB interactions	COPA ZFYVE16 NTRK1 UBR4 DEPDC1 PTK7 CSF1R LRBA HELLS	7.96e-06	228	118	9	int:PDGFRB
Interaction	RPS6KL1 interactions	MAP1B MYO5A UBR4 NUP188 DYNC1H1	1.20e-05	51	118	5	int:RPS6KL1
Interaction	FGFR1 interactions	DVL1P1 ANK2 COPA ZFYVE16 NTRK1 FRS3 NBEA PTK7 KL NISCH ARHGAP29 NUP188 LRBA SMCR8	2.00e-05	632	118	14	int:FGFR1
Cytoband	1q44	OR2L8 OR2L3 OR2L5 OR2L13 OR2L2	1.29e-05	110	124	5	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2L8 OR2L3 OR2L5 OR2L13 OR2L2	2.69e-05	128	124	5	chr1q44
GeneFamily	Myosins, class V	MYO5A MYO5B	6.23e-05	3	83	2	1100
GeneFamily	Olfactory receptors, family 2	OR2L8 OR2L3 OR2L5 OR2L13 OR2L2	1.72e-04	113	83	5	149
GeneFamily	Phosphodiesterases	PDE2A PDE1B PDE10A	1.76e-04	24	83	3	681
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR2 UBR4	4.31e-04	7	83	2	785
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA LRBA	7.34e-04	9	83	2	1230
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	NTRK1 PTK7 CSF1R	8.15e-04	40	83	3	321
GeneFamily	X-linked mental retardation\|RNA helicases	SUPV3L1 ASCC3	1.11e-03	11	83	2	1168
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR1 MTM1	2.10e-03	15	83	2	903
GeneFamily	DNA helicases	ASCC3 HELLS	2.71e-03	17	83	2	1167
GeneFamily	NLR family	NLRP11 NLRP14	5.83e-03	25	83	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP11 NLRP14	5.83e-03	25	83	2	994
Coexpression	CARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP	MAP1B MYO5A DEPDC1 LGR5 PTK7 GRK3 NCAPD2 DYNC1H1	9.49e-07	162	122	8	M45037
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B NBEA GRK3 NISCH VPS13A G6PC2 ASCC3 DYNC1H1	7.73e-08	195	124	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B NBEA GRK3 NISCH VPS13A G6PC2 ASCC3 DYNC1H1	7.73e-08	195	124	8	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 COPA MAP1B UBR4 GRK3 NISCH G6PC2	1.22e-06	194	124	7	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THNSL1 MYO5A ZFYVE16 EMC9 MAP3K6 ZBTB5	6.94e-06	165	124	6	1d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B AARD TAAR6 POSTN BMP5 SPOCD1	1.25e-05	183	124	6	6b5eef96b28911c752a8b6c0975918c4572cec38
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	UBR2 BIRC6 ANKRD44 MTM1 LRBA HELLS	1.33e-05	185	124	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	UBR2 BIRC6 ANKRD44 MTM1 LRBA HELLS	1.37e-05	186	124	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO5B DEPDC1 LRRC9 ZNF827 CCDC87 HELLS	1.46e-05	188	124	6	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 PDE10A BMP5 SCUBE2 ABCA6 MYO16	1.50e-05	189	124	6	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLA1 DEPDC1 NCAPD2 CCR8 RPA2 HELLS	1.59e-05	191	124	6	239300ff76f2c855b2b04d3002461158be90a01b
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 PDE10A GRK3 SCUBE2 ABCA6 MYO16	1.59e-05	191	124	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPA MAP1B UBR4 GRK3 NISCH G6PC2	1.64e-05	192	124	6	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 PDE10A PTK7 BMP5 ABCA6 MYO16	1.64e-05	192	124	6	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 COPA UBR4 GRK3 NISCH G6PC2	1.69e-05	193	124	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 MAP1B MYO5A KIF26A NBEA GRK3	1.69e-05	193	124	6	a189d46c39067b717509cd144e0225cc93d7731d
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 COPA UBR4 GRK3 NISCH G6PC2	1.69e-05	193	124	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 BMP5 SCUBE2 ABCA6 LRFN5 MYO16	1.74e-05	194	124	6	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 PDE10A BMP5 ABCA6 LRFN5 MYO16	1.74e-05	194	124	6	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 BMP5 ABCA6 LRFN5 MYO16	1.90e-05	197	124	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	GPHN UBR2 MAGI3 NBEA BIRC6 LRBA	2.01e-05	199	124	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 BMP5 SCUBE2 ABCA6 MYO16	2.07e-05	200	124	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 BMP5 SCUBE2 ABCA6 MYO16	2.07e-05	200	124	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 MED14 ABCA6 LRFN5 SUPV3L1	4.86e-05	142	124	5	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO5B POLA1 CCDC172 IFNW1 PLXNA1	5.19e-05	144	124	5	bdd6d00b2d1c9dad989df82367a60e8be79de816
ToppCell	368C-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ACSL6 MAP3K6 NLRP14 LRFN5 HELLS	6.30e-05	150	124	5	c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell	368C-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ACSL6 MAP3K6 NLRP14 LRFN5 HELLS	6.30e-05	150	124	5	78b8029e71d26f336a46274c8afef3435bf536b9
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAP1B DEPDC1 CCDC172 POSTN BMP5	6.51e-05	151	124	5	32d35906f4b2bd46b173e87f2dec972eb5da87b3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK1 TRPC1 EMC9 MAGI3 LRRC9	6.71e-05	152	124	5	655d47efe0608d729801f1f01668e84c1bc0675f
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	CDC42BPG EMC9 DEPDC1 MAP3K6 NCAPD2	7.59e-05	156	124	5	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG5 MYO5B ADAM30 DEPDC1 CSF1R	9.07e-05	162	124	5	b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCell	368C-Fibroblasts-Fibroblast-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	MAP3K6 NLRP14 ABCA6 LRFN5 HELLS	9.07e-05	162	124	5	e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell	368C-Fibroblasts-Fibroblast-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	MAP3K6 NLRP14 ABCA6 LRFN5 HELLS	9.07e-05	162	124	5	ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR4 PAQR4 LCAT CSF1R LRBA	9.07e-05	162	124	5	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF26A DVL1 LCAT ZNF827 SERAC1	1.08e-04	168	124	5	32e4d82efaccf336d347e4063253c3635a3ec672
ToppCell	3'_v3-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	ATP6V0A1 NTRK1 EPS15L1 ZBTB5 SERAC1	1.14e-04	170	124	5	4dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell	AT1_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	ADGRG5 ACSL6 THNSL1 BMP5	1.17e-04	90	124	4	6cbf30dd3992d8ccfaa74ad9781b9f8735f1ef69
ToppCell	droplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG5 POLA1 DEPDC1 NCAPD2 HELLS	1.23e-04	173	124	5	20a20429aa898097d5ec4880ed64846558b5890f
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLA1 DEPDC1 NCAPD2 RPA2 HELLS	1.27e-04	174	124	5	c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPC1 DCT POSTN BMP5 ABCA6	1.27e-04	174	124	5	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EMC9 KL UNC79 PLXNA1 MYO16	1.41e-04	178	124	5	d3a75a8082e70543b84c35d53fe77625300d19fa
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EMC9 KL UNC79 PLXNA1 MYO16	1.41e-04	178	124	5	b2cda1df801b1a1a41e3dd2808baef37765cd804
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1B MYO5A PDE10A LRFN5 G6PC2	1.45e-04	179	124	5	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRS3 DEPDC1 PTK7 NCAPD2 PLXNA1	1.56e-04	182	124	5	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 MAP1B MYO5A NBEA GRK3	1.56e-04	182	124	5	be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	HTR2C MAP1B LRRC9 CFAP54 DNAAF1	1.56e-04	182	124	5	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	18-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	MYO5B PAQR4 LCA5L CFAP54 DNAAF1	1.60e-04	183	124	5	a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLA1 PAQR4 NBEA STK35 HELLS	1.65e-04	184	124	5	b998803180322a5ea2b567928dea531c26816c3c
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B AARD TAAR6 POSTN SPOCD1	1.65e-04	184	124	5	5cfc19ffb9f074bdf0d81c86e212a708ec141631
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PDE2A ESR2 PDE10A POSTN ARHGAP29	1.69e-04	185	124	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PDE1B MAP1B ZDBF2 LRFN5 UNC79	1.73e-04	186	124	5	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SETD1A AARS1 ATP6V0A1 CCDC137 MAP3K6	1.73e-04	186	124	5	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DEPDC1 POSTN LRFN5 NCAPD2 HELLS	1.77e-04	187	124	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DEPDC1 POSTN LRFN5 NCAPD2 HELLS	1.77e-04	187	124	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SETD1A AARS1 ATP6V0A1 CCDC137 MAP3K6	1.77e-04	187	124	5	1eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	MTMR1 MAGI3 NBEA SCUBE2 LRBA	1.77e-04	187	124	5	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	MTMR1 MAGI3 NBEA SCUBE2 LRBA	1.77e-04	187	124	5	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	GPHN PDE2A PDE1B MYO5B PDE10A	1.82e-04	188	124	5	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 MAP1B GRK3 NISCH G6PC2	1.82e-04	188	124	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	severe_influenza-Platelet\|World / disease group, cell group and cell class (v2)	MAP1B OR2L5 RSU1 PTK7 SPOCD1	1.82e-04	188	124	5	b54632baa682aaf51100d44e7f114a54d5edd695
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 BMP5 SCUBE2 ABCA6 MYO16	1.86e-04	189	124	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	ZNF132 POLA1 DEPDC1 OR2L2 HELLS	1.86e-04	189	124	5	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HTR2C ANK2 KL VPS13A UNC79	1.91e-04	190	124	5	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBR2 BIRC6 ANKRD44 LRBA HELLS	1.96e-04	191	124	5	9454f642c3621370fa23640b631301346b300950
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPDC1 ERN2 NCAPD2 UNC79 HELLS	1.96e-04	191	124	5	c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 PDE10A BMP5 ABCA6 MYO16	2.01e-04	192	124	5	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 BMP5 SCUBE2 ABCA6 MYO16	2.01e-04	192	124	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZFYVE16 BIRC6 ATP11B SMCR8 DYNC1H1	2.05e-04	193	124	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPA UBR4 GRK3 NISCH G6PC2	2.10e-04	194	124	5	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIF26A PDE10A POSTN KL ARHGAP29	2.10e-04	194	124	5	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	ANK2 POSTN BMP5 ABCA6 LRFN5	2.10e-04	194	124	5	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP1B AARD LGR5 POSTN BMP5	2.10e-04	194	124	5	c992e3357f4bf3069f8d697803e5785e49a2ef0a
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIF26A PDE10A POSTN KL ARHGAP29	2.10e-04	194	124	5	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	IPF-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	MAP1B POSTN BMP5 ABCA6 LRFN5	2.21e-04	196	124	5	7fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCell	IPF-Stromal-Myofibroblast\|IPF / Disease state, Lineage and Cell class	ANK2 POSTN BMP5 ABCA6 LRFN5	2.21e-04	196	124	5	2d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCell	droplet-Tongue-nan-3m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC31A1 OTOP2 DCT MAP3K6 ANKRD44	2.21e-04	196	124	5	159061fd0961b2cfb5941d403acc5b395dd0d3a0
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZDBF2 ANKRD44 VPS13A LRBA HELLS	2.26e-04	197	124	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAP1B TRPC1 ZDBF2 PDE10A ABCA6	2.26e-04	197	124	5	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	P03-Mesenchymal-myocytic_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK2 MAP1B AARD PDE10A POSTN	2.26e-04	197	124	5	079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 MAP1B KIF26A NBEA GRK3	2.31e-04	198	124	5	b58138581f1a9073267d64c1211c5b9b4de71d3e
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UBR2 ANKRD44 PHC3 VPS13A LRBA	2.37e-04	199	124	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.37e-04	199	124	5	e98ff036d04fc78dffef156bdc0d644532274067
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 MAP1B KIF26A NBEA GRK3	2.37e-04	199	124	5	b4824d3683a4e3025b8e74a0f1755b331b2a0ba7
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PTK7 BMP5 SCUBE2 ABCA6 MYO16	2.37e-04	199	124	5	38ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.37e-04	199	124	5	305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 BMP5 ABCA6 MYO16	2.37e-04	199	124	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.37e-04	199	124	5	7feedb0bf84a3361c8ab5b6674ff64e8ff140c23
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.37e-04	199	124	5	123fbf2122aa221d8cbf3aef9361ba0982c07695
ToppCell	COVID-19_Severe-Lymphoid_T/NK-T/NK_proliferative\|COVID-19_Severe / Disease group, lineage and cell class	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.37e-04	199	124	5	ddae7fe7633661f15d3c79f5187415ffbfecce67
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.37e-04	199	124	5	fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 BMP5 ABCA6 MYO16	2.37e-04	199	124	5	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.37e-04	199	124	5	6b1304417cf9c44ca70d2bfc2b5acc1a206f25b6
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 ABCA6 DHCR7 MYO16	2.37e-04	199	124	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AARD BMP5 CFAP54 SCUBE2 FHDC1	2.42e-04	200	124	5	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 BMP5 ABCA6 MYO16	2.42e-04	200	124	5	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK2 PTK7 BMP5 ABCA6 MYO16	2.42e-04	200	124	5	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 MAP1B BMP5 ABCA6 LRFN5	2.42e-04	200	124	5	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-T/NK_proliferative\|COVID-19_Severe / Disease, condition lineage and cell class	POLA1 PAQR4 DEPDC1 NCAPD2 HELLS	2.42e-04	200	124	5	0892603e604c2a945dd720685d45970f855bd5d3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial\|10w / Sample Type, Dataset, Time_group, and Cell type.	DCT POSTN ARHGAP29 FHDC1 SMCR8	2.42e-04	200	124	5	ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AARD BMP5 CFAP54 SCUBE2 FHDC1	2.42e-04	200	124	5	f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	HTR2C ZFYVE16 DCT LRRC9 DNAAF1	2.42e-04	200	124	5	5fb90118d3abc28d72bc483e68317255090a04c7
Disease	Familial medullary thyroid carcinoma	NTRK1 ESR2	4.58e-05	3	116	2	C1833921
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	AARS1 MTMR1 MTM1	1.13e-04	24	116	3	DOID:10595 (implicated_via_orthology)
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	1.52e-04	5	116	2	DOID:11198 (is_implicated_in)
Disease	neurodegenerative disease (implicated_via_orthology)	UBR2 DVL1P1 TRPC1 DVL1 DYNC1H1	2.77e-04	145	116	5	DOID:1289 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	PDE2A ANK2 ESR2 UBR4 EFCAB13 MED14 MAP3K6 NLRP14 CSF1R NISCH ARHGAP29 LRBA SPOCD1	3.15e-04	1074	116	13	C0006142
Disease	Intellectual Disability	SETD1A MAP1B SLC31A1 NBEA DHCR7 SERAC1 ASCC3 DYNC1H1	3.98e-04	447	116	8	C3714756
Disease	S-6-hydroxywarfarin to S-warfarin ratio measurement	BIRC6 NPFFR2 BMP5 HELLS	4.10e-04	88	116	4	EFO_0803332
Disease	cerebellar ataxia (implicated_via_orthology)	AARS1 VPS13A	4.22e-04	8	116	2	DOID:0050753 (implicated_via_orthology)
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR1 MTM1	5.42e-04	9	116	2	DOID:0111225 (implicated_via_orthology)
Disease	colitis (biomarker_via_orthology)	NTRK1 ESR2 CHUK	6.08e-04	42	116	3	DOID:0060180 (biomarker_via_orthology)
Disease	familial hyperlipidemia (implicated_via_orthology)	LCAT KL	9.86e-04	12	116	2	DOID:1168 (implicated_via_orthology)
Disease	Skin Abnormalities	CHUK SUPV3L1	1.16e-03	13	116	2	C0037268
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	CSF1R EIF2B2	1.35e-03	14	116	2	C1858991
Disease	Alopecia, Male Pattern	SUPV3L1 ZDHHC13	1.56e-03	15	116	2	C4083212
Disease	Androgenetic Alopecia	SUPV3L1 ZDHHC13	1.56e-03	15	116	2	C0162311
Disease	Female pattern alopecia (disorder)	SUPV3L1 ZDHHC13	1.56e-03	15	116	2	C0263477
Disease	asthma (biomarker_via_orthology)	NTRK1 ESR2 CCR8	1.64e-03	59	116	3	DOID:2841 (biomarker_via_orthology)
Disease	Neuralgia, Supraorbital	HTR2C NTRK1	1.77e-03	16	116	2	C0038870
Disease	Neuralgia	HTR2C NTRK1	1.77e-03	16	116	2	C0027796
Disease	idiopathic scoliosis (implicated_via_orthology)	PTK7 DNAAF1	1.77e-03	16	116	2	DOID:0060250 (implicated_via_orthology)
Disease	Neuralgia, Atypical	HTR2C NTRK1	1.77e-03	16	116	2	C0234247
Disease	Neuralgia, Stump	HTR2C NTRK1	1.77e-03	16	116	2	C0234249
Disease	Neuralgia, Iliohypogastric Nerve	HTR2C NTRK1	1.77e-03	16	116	2	C0423712
Disease	Neuralgia, Perineal	HTR2C NTRK1	1.77e-03	16	116	2	C0423711
Disease	Paroxysmal Nerve Pain	HTR2C NTRK1	1.77e-03	16	116	2	C0751373
Disease	Nerve Pain	HTR2C NTRK1	1.77e-03	16	116	2	C0751372
Disease	Neuralgia, Ilioinguinal	HTR2C NTRK1	1.77e-03	16	116	2	C0751371
Disease	Neuralgia, Vidian	HTR2C NTRK1	1.77e-03	16	116	2	C0042656
Disease	Post-Traumatic Osteoporosis	RSU1 KL ZDHHC13	1.80e-03	61	116	3	C0751406
Disease	Osteoporosis, Senile	RSU1 KL ZDHHC13	1.80e-03	61	116	3	C0029459
Disease	Osteoporosis, Age-Related	RSU1 KL ZDHHC13	1.80e-03	61	116	3	C0001787
Disease	Colorectal Carcinoma	ANK2 MAP1B ESR2 OTOP2 LGR5 POSTN KL ABCA6 VPS13A	1.85e-03	702	116	9	C0009402
Disease	Osteoporosis	RSU1 KL ZDHHC13	1.98e-03	63	116	3	C0029456
Disease	Charcot-Marie-Tooth disease type 2	AARS1 DYNC1H1	2.00e-03	17	116	2	cv:C0270914
Disease	total blood protein measurement	MTMR1 EPS15L1 CSF1R ABCA6 MTM1 ARHGAP29 ASCC3	2.03e-03	449	116	7	EFO_0004536
Disease	Coronary Arteriosclerosis	ESR2 HECTD4 KL	2.17e-03	65	116	3	C0010054
Disease	Coronary Artery Disease	ESR2 HECTD4 KL	2.17e-03	65	116	3	C1956346
Disease	radiation-induced disorder	TRPC1 PDE10A MYO16	2.36e-03	67	116	3	EFO_0009565
Disease	Pseudopelade	SUPV3L1 ZDHHC13	2.51e-03	19	116	2	C0086873
Disease	Alopecia	SUPV3L1 ZDHHC13	2.51e-03	19	116	2	C0002170
Disease	chronic kidney disease (is_marker_for)	POSTN KL	2.78e-03	20	116	2	DOID:784 (is_marker_for)
Disease	periodontitis (biomarker_via_orthology)	NTRK1 POSTN	3.06e-03	21	116	2	DOID:824 (biomarker_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	HTR2C TRPC1 NBEA LRBA	3.10e-03	152	116	4	DOID:0060041 (implicated_via_orthology)
Disease	anxiety disorder (implicated_via_orthology)	HTR2C ESR2	3.36e-03	22	116	2	DOID:2030 (implicated_via_orthology)
Disease	interleukin 18 measurement	MAP1B BIRC6 ANKRD44	3.38e-03	76	116	3	EFO_0004581

Protein segments in the cluster

Peptide	Gene	Start	Entry
EITLHLQQAMTEHFV	ACCSL	31	Q4AC99
IHRMQQEAQHVLFLS	CCDC137	126	Q6PK04
EIFMHSGLTQNLLAH	EPS15L1	301	Q9UBC2
MHFQNHQLARTLLDL	AARD	111	Q4LEZ3
ELNIHLTMNEFSVHR	GRK3	181	P35626
MDLHLELIQAQHRIA	CFAP54	781	Q96N23
LFSMLQVHHVQLESL	BIRC6	2646	Q9NR09
LQMFNHTQHIRIESS	ABCA6	986	Q8N139
MVNLRNAVHSFLVHL	HTR2C	1	P28335
LTNHETDFLHVIFQM	CCDC87	601	Q9NVE4
ELHSHVTNAMVLVNV	DHCR7	261	Q9UBM7
MSLESLFQHIIFTEH	CCDC172	1	P0C7W6
NLSMILLIFLDIHLH	OR2L2	41	Q8NH16
NLSMILLIFLDTHLH	OR2L3	41	Q8NG85
NAELVFLEIHNIHVM	MTMR1	366	Q13613
KHMHTVTNLFILNLA	NPFFR2	176	Q9Y5X5
MILTNHDHQIRVGVL	GPHN	6	Q9NQX3
HLSVLQVLMTLQLHL	INTS15	291	Q96N11
LAEMVLAIHSLHQLG	CDC42BPG	176	Q6DT37
MLHLHSLSLENNRIT	LRRC9	976	Q6ZRR7
VSLHTLSLDHNMIDN	LRFN5	171	Q96NI6
HVAAFMGHLNIVLLL	ANK2	436	Q01484
LHSILHLVLQAGNIM	FHDC1	291	Q9C0D6
QLSHISHEQNSLFLM	MAML1	546	Q92585
AELLTMLQHQHIVRF	NTRK1	561	P04629
EREQNVLHMLHQILT	HELLS	431	Q9NRZ9
VLFDTMQHHLALNRD	MAP1B	1836	P46821
LGHTHADVVQMFQLV	MAGI3	466	Q5TCQ9
ANLLMLLSHVRHASN	ESR2	456	Q92731
VHFNLTDMLQDAIIH	MYO16	56	Q9Y6X6
ISLNMFSLLHDILHE	NLRP11	701	P59045
FVLMDHILNLKIVHI	CHUK	301	O15111
HILNLKIVHILNMTS	CHUK	306	O15111
VVLQQLMSGLAHLHS	ERN2	616	Q76MJ5
QMLLNHSFTLHTLLT	MAP3K6	1236	O95382
LHLSQFNSMSALHEI	PLXNA1	1841	Q9UIW2
NLSMILLIFLDTHLH	OR2L5	41	Q8NG80
NLSMILLIFLDTHLH	OR2L8	41	Q8NGY9
MEQHHFSQTVSILQL	PDE10A	581	Q9Y233
VLENHHISSVFRLMQ	PDE1B	291	Q01064
MERHHFAQAIAILNT	PDE2A	726	O00408
LVSFLMDHHQEILQV	DEPDC1	671	Q5TB30
VIFVHNTIHLISQVM	LRBA	1351	P50851
MHHKLEAILTENQFL	LCA5L	161	O95447
HLQQLTREAMHLLQA	KIF26A	131	Q9ULI4
HAALNGHVEMVNLLL	ANKRD44	146	Q8N8A2
TNEVINQLLHHVGAM	HECTD4	221	Q9Y4D8
LMLHTAALQQQHLSS	PHC3	76	Q8NDX5
EIIAMAALVHHSFAL	POLA1	556	P09884
QIMHLLSVGSILQLH	PAQR4	241	Q8N4S7
VHSMQISFIHQLVQS	MED14	266	O60244
GLNLTHALLMIAQHT	OTOP2	401	Q7RTS6
TLANSTHHNVRLLML	GBA	306	P04062
KAVTVNLFHMQHLQA	ARHGAP29	426	Q52LW3
HTTIISTHLQAENLM	ADAM30	571	Q9UKF2
IMSHLGQHENIVNLL	CSF1R	636	P07333
HEMLQQIFSLFHTER	IFNW1	81	P05000
VVLFLTSLHSMHILD	CCR8	256	P51685
FTHSNLQPVHMILVL	COPA	1091	P53621
GVMELTQSELVLHLH	FRS3	36	O43559
MTAIQLIQFVLVSLH	ELOVL1	201	Q9BW60
MDFLHRNGVLIIQHL	G6PC2	1	Q9NQR9
ATNHAIVQTLVHLMF	BMP5	396	P22003
DLHTANAILTVMLRH	EFCAB13	861	Q8IY85
HHQIFVFIVDLLQML	TMEM259	326	Q4ZIN3
VLNTLQMAHNHLETV	DNAAF1	196	Q8NEP3
IMVFAHLVHTQLEPL	IPO9	806	Q96P70
LHQDHITFAMLLARI	DYNC1H1	3876	Q14204
QIALLQEMHVTHFRF	KL	581	Q9UEF7
LHGIQHLNMVFSNLT	LCAT	396	P04180
HLNMVFSNLTLEHIN	LCAT	401	P04180
SLNIVTVTLNMERHH	DVL1	246	O14640
HSHLALSVMLEVALN	EMC9	51	Q9Y3B6
LEHIHSNEVIMTIGF	EIF2B2	156	P49770
SLNIITVTLNMERHH	DVL1P1	246	P54792
QMLSFPHLLQTVLHI	SLC31A1	126	O15431
VHREQFHLQLSGMNL	SCUBE2	596	Q9NQ36
HTLAILHEMLQQIFS	IFNE	76	Q86WN2
SALQAMTLALNKIHH	LGR5	186	O75473
LNMTHLAHQVTIDRF	OTOG	2171	Q6ZRI0
FRVDNNHLLLLMIHV	PLEKHM2	586	Q8IWE5
NHLLLLMIHVFRENE	PLEKHM2	591	Q8IWE5
HNHFSQIVIFMLCTL	OR10K2	191	Q6IF99
LASVGNSAMIHLIHV	OR2L13	36	Q8N349
HITQLVLSHNKLTMV	RSU1	41	Q15404
QSAHVVILFHMFLDR	RTP2	66	Q5QGT7
VIGNMALNEHLHSSI	SERAC1	321	Q96JX3
LLVMISILHFKQLHS	TAAR6	51	Q96RI8
IIFVHNTIHLISQMV	NBEA	1376	Q8NFP9
IMQSHSLDVDIHIVL	SUPV3L1	131	Q8IYB8
HLTSVMGNIIHAQLD	SETD1A	156	O15047
FTQTLAQLSHIEHMF	SMCR8	331	Q8TEV9
TRIHMNLHASVLLLN	ADGRG5	281	Q8IZF4
IHIHSDMFSVQNGLL	ACSL6	656	Q9UKU0
TNIAMLTVLHEIRQH	ASCC3	506	Q8N3C0
TVKIIQMLQHFEHLA	NCAPD2	241	Q15021
GHFHRTMNILELINQ	ATP11B	721	Q9Y2G3
IRVLQAAHMLTDNHL	SPG11	2136	Q96JI7
LVAMLHKSFQLIANH	TRPC1	641	P48995
HLYHSVMLENLELVT	ZNF132	61	P52740
MLQLTSAIAFLHKNH	STK35	341	Q8TDR2
VMDVLLAASHLHLNS	ZBTB5	96	O15062
INLDLQDVSMHINHV	ZNF804B	1096	A4D1E1
HLHSNVMLENFALLS	ZNF749	31	O43361
STQHILVPMHFNLEL	VPS13A	736	Q96RL7
SSIHLAVLFQHMPII	ZDHHC13	151	Q8IUH4
TTHILEVINAHMVLS	RPA2	156	P15927
LFFLDIHNIHVMRES	MTM1	306	Q13496
IMSNHTATHILNFAL	AARS1	601	P49588
RHLESLATMSHQLQA	SPOCD1	1151	Q6ZMY3
HCFLQHLMVVLSSLE	NISCH	1266	Q9Y2I1
SSLMERFLQDVLQHH	ZDBF2	41	Q9HCK1
MKQNLHFTEATLHLL	NUP188	1326	Q5SRE5
LMTELFNRLESQHHF	THNSL1	586	Q8IYQ7
LDSQVMSLHNLVHSF	DCT	361	P40126
VMLENFRNLLSVGHH	ZNF234	36	Q14588
TELNVQFVSHMSLHV	ZNF827	906	Q17R98
IHMLFGVSLSLFNHI	ATP6V0A1	546	Q93050
HGSLVNIVQHIIMSN	TOPORS	311	Q9NS56
NVNVELLNALHSHMI	POSTN	156	Q15063
HLVTMAHIIQILLTS	UBR2	1446	Q8IWV8
LNVEHLQMLLLIFHN	UBR4	806	Q5T4S7
MHIFQNGSLVIHDVA	PTK7	641	Q13308
QYTLHNIDQLLIHME	ZFYVE16	1236	Q7Z3T8
GIDHQTVHQLITVLM	UNC79	1271	Q9P2D8
ISTSLIHNKNLMHLD	NLRP14	721	Q86W24
GHQFRNSLHLLMETL	MYO5A	636	Q9Y4I1
HQMSIFKIIASILHL	MYO5B	321	Q9ULV0