Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDishevelled

DVL1P1 DVL1 DVL2

2.14e-0641533PF02377
DomainDishevelled_fam

DVL1P1 DVL1 DVL2

2.14e-0641533IPR008339
DomainDishevelled_protein_dom

DVL1P1 DVL1 DVL2

2.14e-0641533IPR003351
DomainIg_I-set

SEMA3C MXRA5 MYLK PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

3.82e-0619015310IPR013098
DomainI-set

SEMA3C MXRA5 MYLK PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

3.82e-0619015310PF07679
DomainIGc2

SEMA3F MXRA5 MYLK PSG4 PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

3.85e-0623515311SM00408
DomainIg_sub2

SEMA3F MXRA5 MYLK PSG4 PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

3.85e-0623515311IPR003598
DomainCCP

SELL IL15RA CR1 SEZ6L2 SVEP1 C7

5.11e-06541536SM00032
DomainSUSHI

SELL IL15RA CR1 SEZ6L2 SVEP1 C7

6.34e-06561536PS50923
DomainSushi_SCR_CCP_dom

SELL IL15RA CR1 SEZ6L2 SVEP1 C7

7.04e-06571536IPR000436
DomainIG

SEMA3F SEMA3C MXRA5 MYLK PSG4 ICAM1 SEMA3G PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

9.80e-0642115314SM00409
DomainIg_sub

SEMA3F SEMA3C MXRA5 MYLK PSG4 ICAM1 SEMA3G PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

9.80e-0642115314IPR003599
DomainDIX

DVL1P1 DVL1 DVL2

1.84e-0571533PF00778
DomainDIX

DVL1P1 DVL1 DVL2

1.84e-0571533IPR001158
DomainDIX

DVL1P1 DVL1 DVL2

1.84e-0571533PS50841
DomainDAX

DVL1P1 DVL1 DVL2

1.84e-0571533SM00021
DomainGrowth_fac_rcpt_

LAMA3 CUBN SVEP1 GPR179 SCUBE2 HMCN1 ADGRE1 PCSK4

4.40e-051561538IPR009030
DomainCUB

CUBN SEZ6L2 SCUBE2 NETO2 CUZD1

4.93e-05491535PF00431
DomainIG_LIKE

SEMA3F SEMA3C MXRA5 MYLK PSG4 ICAM1 SEMA3G PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

5.33e-0549115314PS50835
DomainCUB

CUBN SEZ6L2 SCUBE2 NETO2 CUZD1

5.44e-05501535SM00042
Domain-

CUBN SEZ6L2 SCUBE2 NETO2 CUZD1

6.58e-055215352.60.120.290
DomainSushi

SELL CR1 SEZ6L2 SVEP1 C7

6.58e-05521535PF00084
DomainDVL-1

DVL1P1 DVL1

6.67e-0521532IPR008340
DomainIg-like_dom

SEMA3F SEMA3C MXRA5 MYLK PSG4 ICAM1 SEMA3G PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

6.90e-0550315314IPR007110
DomainCUB

CUBN SEZ6L2 SCUBE2 NETO2 CUZD1

7.22e-05531535PS01180
Domain-

SEMA3F SEMA3C WDR25 SEMA3G BIRC6 TBL3 CFAP52 RPTOR BOP1 WDR73 WDR77

9.64e-05333153112.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA3F SEMA3C WDR25 SEMA3G BIRC6 TBL3 CFAP52 RPTOR BOP1 WDR73 WDR77

1.02e-0433515311IPR015943
DomainCUB_dom

CUBN SEZ6L2 SCUBE2 NETO2 CUZD1

1.03e-04571535IPR000859
DomainEGF

SELL ADAM23 LAMA3 CUBN SVEP1 GPR179 SCUBE2 HMCN1 ADGRE1

1.41e-042351539SM00181
DomainDishevelled_C-dom

DVL1 DVL2

1.99e-0431532IPR024580
DomainDsh_C

DVL1 DVL2

1.99e-0431532PF12316
DomainEGF-like_dom

SELL ADAM23 LAMA3 CUBN SVEP1 SCUBE2 HMCN1 C7 ADGRE1

2.17e-042491539IPR000742
DomainEGF_1

SELL ADAM23 LAMA3 CUBN SVEP1 SCUBE2 HMCN1 C7 ADGRE1

2.59e-042551539PS00022
DomainEGF-like_CS

SELL ADAM23 LAMA3 CUBN SVEP1 SCUBE2 HMCN1 C7 ADGRE1

3.07e-042611539IPR013032
DomainEGF_2

SELL ADAM23 LAMA3 CUBN SVEP1 SCUBE2 HMCN1 C7 ADGRE1

3.43e-042651539PS01186
Domain-

SEMA3F SEMA3C POGLUT3 MXRA5 MYLK PSG4 ICAM1 SEMA3G PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

3.66e-04663153152.60.40.10
DomainARM-like

SMG1 CAND1 CKAP5 TRIP12 RPTOR AP3B2 TNPO3 HEATR3 KPNA3

3.93e-042701539IPR011989
DomainGPCR_chapero_1

ANKRD13B ANKRD13C

3.96e-0441532PF11904
DomainDsh/Dvl-rel

DVL1 DVL2

3.96e-0441532IPR015506
DomainANKRD13

ANKRD13B ANKRD13C

3.96e-0441532IPR021832
DomainARM-type_fold

SMG1 CAND1 RNPEPL1 CKAP5 TRIP12 RPTOR AP3B2 TNPO3 HEATR3 KPNA3

4.93e-0433915310IPR016024
Domain-

CAND1 CKAP5 TRIP12 RPTOR AP3B2 TNPO3 HEATR3 KPNA3

4.97e-0422215381.25.10.10
DomainSemaphorin

SEMA3F SEMA3C SEMA3G

5.55e-04201533IPR027231
DomainHEAT

CAND1 CKAP5 RPTOR HEATR3

6.37e-04481534PF02985
DomainZnf_FCS

MBTD1 L3MBTL2

6.56e-0451532IPR012313
DomainIg-like_fold

SEMA3F SEMA3C POGLUT3 MXRA5 MYLK PSG4 ICAM1 SEMA3G PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

7.02e-0470615315IPR013783
DomainEGF_CA

CUBN SVEP1 SCUBE2 HMCN1 ADGRE1

7.06e-04861535PF07645
DomainEGF_3

SELL ADAM23 CUBN SVEP1 SCUBE2 HMCN1 C7 ADGRE1

7.22e-042351538PS50026
DomainDEP

DVL1P1 DVL1 DVL2

7.40e-04221533PF00610
DomainDEP

DVL1P1 DVL1 DVL2

7.40e-04221533PS50186
DomainDEP

DVL1P1 DVL1 DVL2

7.40e-04221533SM00049
DomainDEP_dom

DVL1P1 DVL1 DVL2

8.46e-04231533IPR000591
DomainZF_FCS

MBTD1 L3MBTL2

9.79e-0461532PS51024
DomainEGF_Ca-bd_CS

CUBN SVEP1 SCUBE2 HMCN1 ADGRE1

1.22e-03971535IPR018097
DomaincEGF

SCUBE2 HMCN1 ADGRE1

1.22e-03261533PF12662
DomaincEGF

SCUBE2 HMCN1 ADGRE1

1.22e-03261533IPR026823
DomainHEAT

CAND1 CKAP5 RPTOR HEATR3

1.30e-03581534IPR000357
DomainEGF_CA

CUBN SVEP1 SCUBE2 HMCN1 ADGRE1

1.33e-03991535PS01187
Domain4HBT

THEM4 ACOT11

1.36e-0371532PF03061
DomainThioestr_dom

THEM4 ACOT11

1.36e-0371532IPR006683
DomainASX_HYDROXYL

CUBN SVEP1 SCUBE2 HMCN1 ADGRE1

1.39e-031001535PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

CUBN SVEP1 SCUBE2 HMCN1 ADGRE1

1.80e-031061535IPR000152
DomainSemap_dom

SEMA3F SEMA3C SEMA3G

2.05e-03311533IPR001627
DomainSEMA

SEMA3F SEMA3C SEMA3G

2.05e-03311533PS51004
DomainSema

SEMA3F SEMA3C SEMA3G

2.05e-03311533SM00630
DomainSema

SEMA3F SEMA3C SEMA3G

2.05e-03311533PF01403
DomainPeptidase_S8_His-AS

TPP2 PCSK4

2.31e-0391532IPR022398
DomainMBT

MBTD1 L3MBTL2

2.31e-0391532SM00561
DomainMBT

MBTD1 L3MBTL2

2.31e-0391532PS51079
DomainPeptidase_S8_Ser-AS

TPP2 PCSK4

2.31e-0391532IPR023828
DomainHEAT_REPEAT

SMG1 CAND1 CKAP5 HEATR3

2.61e-03701534PS50077
DomainMBT

MBTD1 L3MBTL2

2.87e-03101532PF02820
DomainMbt

MBTD1 L3MBTL2

2.87e-03101532IPR004092
Domain-

THEM4 ACOT11

2.87e-031015323.10.129.10
DomainPeptidase_S8_subtilisin-rel

TPP2 PCSK4

2.87e-03101532IPR015500
DomainHotDog_dom

THEM4 ACOT11

2.87e-03101532IPR029069
DomainSUBTILASE_ASP

TPP2 PCSK4

2.87e-03101532PS00136
DomainSUBTILASE_HIS

TPP2 PCSK4

2.87e-03101532PS00137
DomainSUBTILASE_SER

TPP2 PCSK4

2.87e-03101532PS00138
DomainWD40_repeat_dom

WDR25 LRRK1 TBL3 CFAP52 RPTOR BOP1 WDR73 WDR77

3.16e-032971538IPR017986
DomainEGF_CA

CUBN SVEP1 SCUBE2 HMCN1 ADGRE1

3.32e-031221535SM00179
Domain-

TPP2 PCSK4

3.49e-031115323.40.50.200
DomainGFP-like

SVEP1 HMCN1

3.49e-03111532IPR023413
DomainEphrin_rec_like

SVEP1 SCUBE2

3.49e-03111532PF07699
DomainR3H

NFX1 PARN

3.49e-03111532PS51061
DomainPeptidase_S8/S53_dom

TPP2 PCSK4

3.49e-03111532IPR000209
Domain-

SVEP1 HMCN1

3.49e-031115322.40.155.10
DomainR3H

NFX1 PARN

3.49e-03111532PF01424
Domain-

NFX1 PARN

3.49e-031115323.30.1370.50
DomainPeptidase_S8

TPP2 PCSK4

3.49e-03111532PF00082
DomainR3H_dom

NFX1 PARN

3.49e-03111532IPR001374
DomainEGF-like_Ca-bd_dom

CUBN SVEP1 SCUBE2 HMCN1 ADGRE1

3.56e-031241535IPR001881
DomainEGF

SELL CUBN SVEP1 SCUBE2 HMCN1

3.81e-031261535PF00008
DomainEGF_dom

CUBN SCUBE2

4.17e-03121532IPR024731
DomainEGF_3

CUBN SCUBE2

4.17e-03121532PF12947
DomainASP_PROTEASE

ERVK-6 BACE2

4.17e-03121532PS00141
DomainAspartic_peptidase_AS

ERVK-6 BACE2

4.90e-03131532IPR001969
DomainWD40

WDR25 TBL3 CFAP52 RPTOR BOP1 WDR73 WDR77

5.55e-032591537PF00400
DomainPSI

SEMA3F SEMA3C SEMA3G

5.58e-03441533IPR016201
DomainTyr_kinase_cat_dom

PTK7 JAK1 KDR MUSK

5.93e-03881534IPR020635
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TPP2 SEMA3C POGLUT3 CAND1 ACP2 THUMPD3 STK11IP TRIP12 BIRC6 MBD3 TBL3 IVNS1ABP JAK1 PIGT TJP1 ROBO1 PARN CHID1 CTSB HERC4 PALLD TNPO3 KPNA3

2.84e-0812971592333545068
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

SEMA3F SEMA3C ADAM23 SEMA3G CUBN PTK7 FZD8 NETO2

7.15e-08117159817145500
Pubmed

cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.

DVL1P1 DVL1 DVL2

3.74e-07415938817329
Pubmed

Human dishevelled genes constitute a DHR-containing multigene family.

DVL1P1 DVL1 DVL2

3.74e-07415939192851
Pubmed

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.

DVL1 DVL2 FZD8

5.16e-068159315454084
Pubmed

Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1.

DVL1 DVL2 MUSK

5.16e-068159312165471
Pubmed

Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice.

SEMA3F SEMA3C SEMA3G

5.16e-068159320006658
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 SEMA3C TTC28 ARHGEF5 SLCO4A1 GON4L PTK7 EIF2D YY1AP1 PARN PALLD GARRE1 HEATR3

1.00e-056501591338777146
Pubmed

Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin.

DVL1 DVL2 FZD8

1.10e-0510159315143170
Pubmed

Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.

SEMA3F SEMA3C SEMA3G KDR

1.20e-0531159422076636
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

ADAM23 EXT1 BIRC6 PTK7

1.20e-0531159411431694
Pubmed

Class 3 semaphorins negatively regulate dermal lymphatic network formation.

SEMA3F SEMA3C SEMA3G

1.51e-0511159326319580
Pubmed

Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting.

SEMA3F SEMA3C SEMA3G

2.00e-0512159319812329
Pubmed

Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.

SEMA3F SEMA3C SEMA3G

2.00e-0512159323991118
Pubmed

Microtubules enable the planar cell polarity of airway cilia.

DVL1 DVL2 TJP1

2.00e-0512159323122850
Pubmed

Soluble adhesion molecules in Finnish schoolchildren with signs of preclinical type 1 diabetes.

SELL ICAM1

2.08e-052159214737745
Pubmed

Genetic variants in selenoprotein genes modulate biomarkers of selenium status in response to Brazil nut supplementation (the SU.BRA.NUT study).

SELENOP GPX1

2.08e-052159229609868
Pubmed

MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function.

MYLK TJP1

2.08e-052159220404178
Pubmed

An Assessment of GPX1 (rs1050450), DIO2 (rs225014) and SEPP1 (rs7579) Gene Polymorphisms in Women with Endometrial Cancer.

SELENOP GPX1

2.08e-052159235205233
Pubmed

Newly identified Gon4l/Udu-interacting proteins implicate novel functions.

GON4L YY1AP1

2.08e-052159232848183
Pubmed

Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.

SCUBE2 KDR

2.08e-052159227834687
Pubmed

The transcriptional regulator GON4L is required for viability and hematopoiesis in mice.

GON4L YY1AP1

2.08e-052159233864850
Pubmed

Intercellular adhesion molecule-1 and L-selectin regulate bleomycin-induced lung fibrosis.

SELL ICAM1

2.08e-052159212414509
Pubmed

Increased percentage of L-selectin+ and ICAM-1+ peripheral blood CD4+/CD8+ T cells in active Graves' ophthalmopathy.

SELL ICAM1

2.08e-052159219419934
Pubmed

The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression.

SELL ICAM1

2.08e-052159211884469
Pubmed

Low zone tolerance requires ICAM-1 expression to limit contact hypersensitivity elicitation.

SELL ICAM1

2.08e-052159219536145
Pubmed

Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways.

SELL ICAM1

2.08e-052159210438959
Pubmed

Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.

DVL1P1 DVL1

2.08e-05215928644734
Pubmed

Biphasic effect of PTK7 on KDR activity in endothelial cells and angiogenesis.

PTK7 KDR

2.08e-052159225986862
Pubmed

A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors.

BIRC6 UBE2L3

2.08e-05215929628897
Pubmed

Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1.

SELL ICAM1

2.08e-052159216412045
Pubmed

L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity.

SELL ICAM1

2.08e-052159212682269
Pubmed

Reduced Sympathetic Innervation in Endometriosis is Associated to Semaphorin 3C and 3F Expression.

SEMA3F SEMA3C

2.08e-052159227558236
Pubmed

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.

GON4L YY1AP1

2.08e-052159220530203
Pubmed

Soluble adhesion molecules in young children with signs of beta-cell autoimmunity--prospective follow-up from birth.

SELL ICAM1

2.08e-052159216270299
Pubmed

Molecular docking of SARS-COV-2 Spike epitope sequences identifies heterodimeric peptide-protein complex formation with human Zo-1, TLR8 and brain specific glial proteins.

TLR8 TJP1

2.08e-052159234673372
Pubmed

Age-related changes in apoptosis and expressions of intercellular adhesion molecule-1 and vascular endothelial growth factor receptor type 2 in the wall of varicose veins.

ICAM1 KDR

2.08e-052159221173732
Pubmed

Wnt-mediated relocalization of dishevelled proteins.

DVL1 DVL2

2.08e-05215928856345
Pubmed

Delayed wound healing in the absence of intercellular adhesion molecule-1 or L-selectin expression.

SELL ICAM1

2.08e-052159210880393
Pubmed

Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression.

SELL ICAM1

2.08e-05215929636189
Pubmed

The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity.

SELL ICAM1

2.08e-052159220182448
Pubmed

Intercellular adhesion molecule 1 and selectin l play crucial roles in ulcerative colitis.

SELL ICAM1

2.08e-052159238065859
Pubmed

Selenoprotein gene variants, toenail selenium levels, and risk for advanced prostate cancer.

SELENOP GPX1

2.08e-052159224563517
Pubmed

DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: a short-term supplementation trial with respect to GPX1 and SEPP1 polymorphism.

SELENOP GPX1

2.08e-052159226658762
Pubmed

Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.

ARHGEF19 DVL2

2.08e-052159238714795
Pubmed

Evaluation of the prognostic relevance of L-selectin and ICAM1 expression in myelodysplastic syndromes.

SELL ICAM1

2.08e-052159218028430
Pubmed

A crucial role of L-selectin in C protein-induced experimental polymyositis in mice.

SELL ICAM1

2.08e-052159224644046
Pubmed

Selenoprotein P inhibits cell proliferation and ROX production in HCC cells.

SELENOP GPX1

2.08e-052159232735635
Pubmed

The adhesion molecules of L-selectin and ICAM-1 in thrombocytosis and thrombocytopenia.

SELL ICAM1

2.08e-052159219954409
Pubmed

L-selectin and intercellular adhesion molecule-1 regulate the development of Concanavalin A-induced liver injury.

SELL ICAM1

2.08e-052159216461740
Pubmed

Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1.

SELL ICAM1

2.08e-052159217595378
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TTC28 L3MBTL2 DVL1 DVL2 CKAP5 BIRC6 RLF ZMIZ2 ATF7IP2 CAMSAP1

2.46e-054181591034709266
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CAND1 PSAP ERG TTC28 ADAM23 TTLL5 CKAP5 SYNPO TRIP12 PLEKHH1 JAK1 TJP1 ROBO1 YY1AP1 BACE2 CTSB ZNF292 KPNA3

2.59e-0512851591835914814
Pubmed

Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons.

SEMA3F SEMA3C ROBO1

2.59e-0513159323534961
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

TTC28 AHCTF1 DVL1 DVL2 CKAP5 TJP1 NFX1 CAMSAP1

3.05e-05263159834702444
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

SMG1 POLM TBL3 GPR179 CALHM4 JAK1 FZD8 ZMIZ2 ZFYVE26 WDR73 YY1AP1 BACE2 ZNF679 RAB3IL1

3.09e-058321591436724073
Pubmed

Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury.

DVL2 SYNPO TJP1

3.29e-0514159325145929
Pubmed

Erythro-myeloid progenitors contribute endothelial cells to blood vessels.

ERG KDR ADGRE1

3.29e-0514159330258231
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TTC28 KLHDC2 ARHGEF5 CKAP5 TRIP12 IVNS1ABP TJP1 STARD9 RPTOR CAMSAP1 PALLD GARRE1 TNPO3 MUSK

4.48e-058611591436931259
Pubmed

Identification of APBB1 as a substrate for anaplastic lymphoma kinase.

DVL1 DVL2 PTK7 PALLD

4.95e-0544159439115278
Pubmed

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.

DVL1 DVL2 PTK7

5.03e-0516159322771245
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA3F ARHGEF19 RNPEPL1 DVL1 SLCO4A1 LRRK1 STK11IP BIRC6 MBD3 RPTOR ZMIZ2 NFX1 PIGW ZFYVE26 CAMSAP1 TNPO3

5.06e-0511051591635748872
Pubmed

Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities.

CACNA1C SVEP1

6.21e-053159227529678
Pubmed

Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division.

GON4L YY1AP1

6.21e-053159228381640
Pubmed

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways.

DVL1 DVL2

6.21e-053159215852005
Pubmed

Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3.

DVL1 DVL2

6.21e-053159218093802
Pubmed

DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway.

DVL1 DVL2

6.21e-053159232900645
Pubmed

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.

DVL1 DVL2

6.21e-053159227744318
Pubmed

Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells.

DVL1 DVL2

6.21e-053159220224554
Pubmed

The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency.

TRIP12 UBE2L3

6.21e-053159232755579
Pubmed

Raftlin is recruited by neuropilin-1 to the activated VEGFR2 complex to control proangiogenic signaling.

RFTN1 KDR

6.21e-053159232274611
Pubmed

Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts.

PSAP CTSB

6.21e-053159222949512
Pubmed

Human promoter mutations unveil Oct-1 and GATA-1 opposite action on Gfi1b regulation.

GFI1B SLC22A1

6.21e-053159220143233
Pubmed

Association between polymorphisms in glutathione peroxidase and selenoprotein P genes, glutathione peroxidase activity, HRT use and breast cancer risk.

SELENOP GPX1

6.21e-053159224039907
Pubmed

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway.

DVL1 DVL2

6.21e-053159216116426
Pubmed

ICAM-1-dependent pathways regulate colonic eosinophilic inflammation.

SELL ICAM1

6.21e-053159216731772
Pubmed

Chromosomal localization of the zinc finger protein 15, Zfp15, on mouse chromosome 4.

DVL1 ZNF292

6.21e-05315927613041
Pubmed

FLI1 and ERG protein degradation is regulated via Cathepsin B lysosomal pathway in human dermal microvascular endothelial cells.

ERG CTSB

6.21e-053159232979864
Pubmed

Leukocyte rolling velocities and migration are optimized by cooperative L-selectin and intercellular adhesion molecule-1 functions.

SELL ICAM1

6.21e-053159212370391
Pubmed

The DIX domain targets dishevelled to actin stress fibres and vesicular membranes.

DVL1P1 DVL2

6.21e-053159212384700
Pubmed

Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia.

DVL1 DVL2

6.21e-053159227086035
Pubmed

ICAM-1 deficiency exacerbates sarcoid-like granulomatosis induced by Propionibacterium acnes through impaired IL-10 production by regulatory T cells.

SELL ICAM1

6.21e-053159224103557
Pubmed

Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway.

DVL1 DVL2

6.21e-053159210409711
Pubmed

Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling.

DVL1 DVL2

6.21e-053159221092292
Pubmed

Mechanism of activation of the Formin protein Daam1.

DVL1 DVL2

6.21e-053159218162551
Pubmed

Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice.

SELL ICAM1

6.21e-053159217579093
Pubmed

The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation.

GON4L YY1AP1

6.21e-053159223608756
Pubmed

Genomic organization of mouse Dishevelled genes.

DVL1 DVL2

6.21e-05315928973355
Pubmed

Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression.

DVL1 DVL2

6.21e-053159218692936
Pubmed

Influence of Genetic Variations in Selenoprotein Genes on the Pattern of Gene Expression after Supplementation with Brazil Nuts.

SELENOP GPX1

6.21e-053159228696394
Pubmed

Polymorphism in L-selectin, E-selectin and ICAM-1 genes in Asian Indian pediatric patients with celiac disease.

SELL ICAM1

6.21e-053159216916660
Pubmed

Selenium, selenoenzymes, oxidative stress and risk of neoplastic progression from Barrett's esophagus: results from biomarkers and genetic variants.

SELENOP GPX1

6.21e-053159222715394
Pubmed

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage.

ERG KDR

6.21e-053159220030844
Pubmed

CTLA4-Ig/CD86 interactions in cultured human endothelial cells: effects on VEGFR-2 and ICAM1 expression.

ICAM1 KDR

6.21e-053159225896473
Pubmed

beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins.

DVL1 DVL2

6.21e-053159211742073
Pubmed

Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals.

DVL1 DVL2

6.21e-053159223437169
Pubmed

Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles.

ANKRD13B DVL2 TJP1

7.27e-0518159329229865
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

MBTD1 GPX1 GON4L ZMIZ2 YY1AP1 CTSB VBP1 ZNF292 KPNA3

9.67e-05398159935016035
Pubmed

VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm.

SEMA3F SEMA3C KDR

1.01e-0420159321658587
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TTC28 CKAP5 GON4L PLEKHH1 RSBN1 JMJD6 ACOT11 STARD9 YY1AP1

1.15e-04407159912693553
InteractionSCUBE2 interactions

SYNPO SCUBE2 KDR

1.77e-0641553int:SCUBE2
Cytoband1p32.3-p31.3

JAK1 ANKRD13C

1.19e-05215921p32.3-p31.3
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SEMA3C MXRA5 MYLK PTK7 HMCN1 ROBO1 KDR PALLD MUSK ALPK2

4.74e-0816110910593
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELL IL15RA CR1 SEZ6L2 SVEP1 C7

1.18e-065710961179
GeneFamilyImmunoglobulin like domain containing

SEMA3F MXRA5 ICAM1 SEMA3G PTK7 KDR MUSK

1.69e-041931097594
GeneFamilyDishevelled segment polarity proteins|PDZ domain containing

DVL1 DVL2

2.14e-0441092505
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA3F SEMA3C SEMA3G

2.25e-04201093736
GeneFamilyWD repeat domain containing

WDR25 TBL3 CFAP52 RPTOR BOP1 WDR73 WDR77

1.05e-032621097362
GeneFamilySterile alpha motif domain containing|MBT domain containing

MBTD1 L3MBTL2

1.26e-03910921263
GeneFamilyReceptor Tyrosine Kinases|CD molecules

PTK7 KDR MUSK

1.79e-03401093321
GeneFamilyUbiquitin conjugating enzymes E2

BIRC6 UBE2L3 UBE2L5

1.92e-03411093102
GeneFamilyStAR related lipid transfer domain containing

ACOT11 STARD9

3.59e-03151092759
GeneFamilyArmadillo repeat containing|Importins

TNPO3 KPNA3

5.17e-03181092596
GeneFamilyProteases, serine

PRSS38 PRSS12 PRSS29P

6.51e-03631093738
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGT PIGW

7.02e-03211092680
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SEMA3C CAND1 TTC28 AHCTF1 CKAP5 EXT1 SOCS6 PRR3 TRIP12 RLF RSBN1 RFTN1 MAP4K5 PARN HERC4 GARRE1 ZNF292 KPNA3

3.69e-0685615618M4500
CoexpressionACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN

FAHD2B MXRA5 ACP2 MBD3 MINDY3 ANKRD33 SLC22A1 C7 RAB3IL1 TNPO3

6.07e-0627415610M13014
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_NEGATIVE

TPP2 AHCTF1 GON4L IVNS1ABP JAK1 RSBN1 RHOH ZNF26 ATF7IP2 ZNF292 KPNA3

1.20e-0536315611M41103
CoexpressionGSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN

ADAM23 PRSS12 ICAM1 SYNPO ROBO1 LAS1L PALLD ALPK2

2.66e-051991568M3731
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C MYLK SVEP1 HMCN1 ROBO1 PDE5A C7 PALLD MUSK

1.81e-0818115899ede19228ba5c0668a9c06c915510b95585216ef
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C MYLK SVEP1 HMCN1 ROBO1 PDE5A C7 PALLD MUSK

3.02e-08192158999ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C IL15RA MYLK SVEP1 HMCN1 ROBO1 PDE5A PALLD MUSK

3.16e-08193158999525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK EXT1 SVEP1 RFTN1 ROBO1 PDE5A C7 PALLD

3.30e-08194158990efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK EXT1 SVEP1 RFTN1 ROBO1 PDE5A C7 PALLD

3.30e-081941589df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

CACNA1C MXRA5 MYLK SVEP1 HMCN1 ROBO1 C7 PALLD MUSK

3.30e-08194158903a269f75a481ea54aea8e6444605db8d6df493d
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C MYLK SVEP1 HMCN1 ROBO1 PDE5A C7 PALLD MUSK

3.45e-081951589aa0add081881d349099d12efca5cdee098038d4e
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

CACNA1C MYLK SVEP1 HMCN1 ROBO1 PDE5A C7 PALLD MUSK

3.45e-08195158961c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK ERG SVEP1 RFTN1 HMCN1 PDE5A C7 PALLD

3.60e-081961589fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK ERG SVEP1 RFTN1 HMCN1 PDE5A C7 PALLD

3.60e-081961589802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C MXRA5 MYLK TTC28 SVEP1 HMCN1 ROBO1 C7 PALLD

3.76e-081971589f1c8936986123a3151140c374fcd62d6705c530b
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

3.93e-081981589f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SEMA3F ERG SYNPO EXT1 SEMA3G CALHM4 FZD8 HMCN1

2.60e-0717915888c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SEMA3F ERG TTC28 SLCO4A1 SYNPO SEMA3G TJP1 GARRE1

3.20e-0718415880f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

CACNA1C MYLK SVEP1 HMCN1 ROBO1 C7 PALLD MUSK

3.62e-07187158892d468dde81125d51daf7abd4703741abe1ab91c
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C SEMA3C TTLL5 IVNS1ABP EIF2D HMCN1 UBE2L3 PALLD

3.77e-0718815886468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C SEMA3C TTLL5 IVNS1ABP EIF2D HMCN1 UBE2L3 PALLD

3.77e-0718815887a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C SEMA3C TTLL5 IVNS1ABP EIF2D HMCN1 UBE2L3 PALLD

3.77e-0718815889cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK PRSS38 SVEP1 PTK7 GFI1B C7 PALLD

4.02e-0712915876abdba987c8528f7cb90b32dc01796e02c7352c9
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

CACNA1C MYLK SVEP1 HMCN1 ROBO1 C7 PALLD MUSK

4.09e-0719015883a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C MYLK SVEP1 HMCN1 ROBO1 C7 PALLD MUSK

4.26e-0719115886688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

SELENOP MYLK SVEP1 PTK7 HMCN1 ROBO1 PALLD MUSK

4.43e-07192158862904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellEC-Sinusoidal_ECs|EC / Lineage and Cell class

SELENOP ICAM1 JAK1 MAP4K5 KDR BACE2 CTSB RAB3IL1

4.61e-0719315881291b1d3494dcb4b9309f8bff63fb662e7eca0c8
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA1C MYLK TTC28 SVEP1 HMCN1 ROBO1 C7 PALLD

4.61e-071931588acad568621ed677031797b8c2e34dafea798d681
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3C ERG ADAM23 SEMA3G HMCN1 TJP1 KDR GARRE1

4.79e-0719415887f24023df47935286f185dd428d48797daf26f49
ToppCell(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

SELENOP ICAM1 JAK1 TJP1 MAP4K5 KDR BACE2 CTSB

4.98e-071951588e8ab3122f81cb22920becd6611cbd9f00db19d50
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C MYLK TTC28 SVEP1 HMCN1 ROBO1 C7 PALLD

4.98e-071951588603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CACNA1C MYLK TTC28 SVEP1 ROBO1 PDE5A C7 PALLD

5.18e-071961588dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

5.18e-0719615889737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

5.18e-071961588cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C MYLK SVEP1 HMCN1 ROBO1 C7 PALLD MUSK

5.18e-0719615887d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

5.38e-07197158813896ec65ccda0b928c91d41112dc01b480036b7
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

5.38e-07197158894a9603cbd3516fbcce871909693b88f20d41713
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1C SELENOP MYLK TTC28 SVEP1 ROBO1 PDE5A C7

5.38e-07197158873a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

CACNA1C MYLK TTC28 SVEP1 HMCN1 ROBO1 C7 PALLD

5.38e-071971588fb847f2277609c31fffcdf49517243ce0684facf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C EXT1 SVEP1 RFTN1 MAP4K5 ROBO1 C7 PALLD

5.59e-071981588a860246bcea847249a78fd2e86ed8e04371060db
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C MYLK SVEP1 HMCN1 ROBO1 C7 PALLD MUSK

5.59e-0719815888f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SEMA3C MYLK PRSS12 PTK7 GADL1 ROBO1 PDE5A PALLD

5.81e-07199158838cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SELENOP MYLK PRSS12 SVEP1 PTK7 ROBO1 C7 PALLD

5.81e-07199158830d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1C SELENOP MYLK TTC28 SVEP1 ROBO1 PDE5A C7

5.81e-071991588a09292de4c4447b8eee55d401808e43b817321cc
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD

5.81e-07199158866a79732caf2f04c09b4d9832377aa01ca477677
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CACNA1C MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

6.03e-072001588aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNA1C MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

6.03e-072001588a510deaada669e690329183e18df02870bd204b3
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C MYLK SVEP1 HMCN1 ROBO1 PDE5A C7 PALLD

6.03e-07200158834f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERG TTC28 SLCO4A1 SYNPO SEMA3G HMCN1 TJP1 GARRE1

6.03e-0720015887547d6339f9380d031cfd2cce21ac9a12491e085
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA1C MYLK SVEP1 HMCN1 PDE5A C7 PALLD MUSK

6.03e-072001588dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

CACNA1C SELENOP MXRA5 MYLK SEZ6L2 SVEP1 HMCN1

2.02e-0616415872ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

SELL ERG CR1 SVEP1 RFTN1 HMCN1 MUSK

2.28e-061671587d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

CACNA1C MYLK SVEP1 HMCN1 ROBO1 C7 PALLD

4.81e-061871587bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MYLK EXT1 PTK7 SCUBE2 HMCN1 C7 PALLD

5.16e-061891587dc5164591dea45b420798b94dda211be03daa70c
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MYLK EXT1 PTK7 SCUBE2 HMCN1 C7 PALLD

5.34e-0619015871196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellEndothelial-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SEMA3F ERG ADAM23 SLCO4A1 SEMA3G KDR C7

5.34e-0619015876e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SEMA3F ERG TTC28 SLCO4A1 SEMA3G TJP1 KDR

5.34e-0619015879fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell18-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

SEMA3C MYLK ERG TNFSF18 PTK7 RPTOR PALLD

5.53e-06191158786ce98d2c90c196474b06869de888cf5d1eed196
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

IL15RA SVEP1 RFTN1 STARD9 ROBO1 C7 MUSK

5.53e-06191158770c067c54084bfb02c29bab085f4defd477194fb
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F SEMA3C ERG SEMA3G HMCN1 TJP1 GARRE1

5.72e-0619215874bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|(1)_Control_(PBS) / Stress and Cell class

SELENOP ERG JAK1 HMCN1 TJP1 MAP4K5 KDR

5.72e-061921587e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C MYLK ERG TTC28 HMCN1 ROBO1 PALLD

5.92e-061931587e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F ADAM23 JAK1 TJP1 KDR BACE2 GARRE1

5.92e-0619315878084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C MYLK EXT1 SVEP1 HMCN1 PDE5A PALLD

5.92e-061931587b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellPND14-Endothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELENOP SEMA3C ERG SEMA3G TJP1 KDR GARRE1

6.12e-061941587cee89d4340738f09d07a159cd6aeee4300776988
ToppCellPND14-Endothelial-Endothelial_blood-vessel|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELENOP SEMA3C ERG SEMA3G TJP1 KDR GARRE1

6.12e-06194158732962060d80f3edffbe9f0ecad3000c3a9817865
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

SELENOP MYLK ICAM1 JAK1 MAP4K5 KDR CTSB

6.12e-0619415874199900d16623eca02d674d5ada7f0989e47955e
ToppCell(6)_Endothelial-B_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SEMA3F ERG SLCO4A1 SYNPO SEMA3G CUBN GARRE1

6.12e-0619415870cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1C SELENOP MYLK SVEP1 ROBO1 PDE5A C7

6.12e-0619415878c37bedb23285735ff3828db3889897fada8c95d
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3C ERG SEMA3G HMCN1 TJP1 KDR GARRE1

6.12e-06194158744c7d4b75f3b7c9301eba20610e548a01a84ae40
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C SELENOP MYLK TTC28 SVEP1 HMCN1 C7

6.12e-061941587011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellfacs-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3F SELENOP SEMA3C HMCN1 TJP1 KDR GARRE1

6.12e-0619415873b5ba12375102598468cb09e66af9241b66c3cf9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELENOP SEMA3C ERG SEMA3G TJP1 KDR GARRE1

6.12e-061941587c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

SEMA3F ERG SLCO4A1 RFTN1 HMCN1 KDR GARRE1

6.33e-061951587fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK EXT1 SVEP1 RFTN1 C7 PALLD

6.33e-061951587803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK EXT1 SVEP1 RFTN1 C7 PALLD

6.33e-0619515874f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEMA3F ERG EXT1 SEMA3G HMCN1 KDR C7

6.33e-0619515874658fb197657d7692ee344ae76b11b0210c418ba
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3C ERG ADAM23 SEMA3G TJP1 KDR GARRE1

6.33e-061951587cd011433b3b9bfb1adb13eca2f3f2a5db024cd94
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK EXT1 SVEP1 RFTN1 C7 PALLD

6.55e-0619615872b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SELENOP PSAP ICAM1 GPX1 EXT1 CTSB PALLD

6.55e-061961587bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL15RA ERG TTC28 SEMA3G STARD9 KDR GARRE1

6.55e-061961587145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SELENOP PSAP ICAM1 GPX1 EXT1 CTSB PALLD

6.55e-061961587072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD

6.77e-061971587156155c2f0c1a2461e45803da578af18ee221660
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C ERG EXT1 SVEP1 MAP4K5 C7 PALLD

6.77e-06197158785a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F ADAM23 JAK1 TJP1 KDR BACE2 GARRE1

6.77e-061971587a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD

6.77e-0619715876c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD

6.77e-061971587d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C ERG EXT1 SVEP1 ROBO1 C7 PALLD

6.77e-0619715879b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F ADAM23 JAK1 TJP1 KDR BACE2 GARRE1

6.77e-061971587deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

CACNA1C MYLK SVEP1 HMCN1 ROBO1 C7 MUSK

6.77e-061971587d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C ERG EXT1 SVEP1 MAP4K5 C7 PALLD

6.77e-061971587e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C MYLK EXT1 SVEP1 RFTN1 C7 PALLD

6.77e-06197158780e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

CACNA1C MYLK SVEP1 HMCN1 ROBO1 PDE5A C7

6.99e-06198158726e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C MYLK TTC28 EXT1 SVEP1 HMCN1 C7

6.99e-06198158721cf4d81386761d09d0f6829c01c198e5524176d
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C SELENOP MYLK SVEP1 HMCN1 ROBO1 C7

6.99e-0619815873ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C MXRA5 MYLK SVEP1 HMCN1 ROBO1 C7

6.99e-061981587300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1C SELENOP MYLK TTC28 SVEP1 ROBO1 C7

6.99e-06198158717dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL15RA ERG ICAM1 SLCO4A1 SYNPO SEMA3G GARRE1

7.23e-0619915876e3a226ebba023e3e909d7a7188137da4f1fd7fc
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SELENOP MYLK SVEP1 HMCN1 PDE5A C7 PALLD

7.23e-061991587b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MXRA5 MYLK SVEP1 HMCN1 PDE5A C7 MUSK

7.23e-061991587e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SELENOP MXRA5 MYLK SVEP1 PTK7 C7 PALLD

7.23e-061991587e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

SELENOP MXRA5 MYLK SVEP1 HMCN1 C7 PALLD

7.23e-0619915879c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK LAMA3 SVEP1 SCUBE2 ZNF804B C7 MUSK

7.23e-0619915870cdbedf09ec72734b86ddab3fec562e066afed92
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

CACNA1C MYLK TTC28 SVEP1 HMCN1 ROBO1 C7

7.23e-0619915874bac110c2b3609f6ee5d0e3275da0824a6240270
Diseasesalivary gland cancer (implicated_via_orthology)

GON4L YY1AP1

2.53e-0521492DOID:8850 (implicated_via_orthology)
DiseaseAutistic Disorder

CACNA1C HTR1D GPX1 EXT1 SEZ6L2 MBD3 ROBO1 ZNF292

5.73e-052611498C0004352
Diseasetriacylglycerol 56:6 measurement

AHCTF1 MAP4K5 RAB3IL1 MUSK

6.61e-05431494EFO_0010433
Diseaseserum gamma-glutamyl transferase measurement

ARHGEF19 GALNT3 ICAM1 GON4L UBE2L3 TJP1 MAP4K5 ZMIZ2 SLC22A1 ROBO1 YY1AP1 RAB3IL1 ALPK2 ZNF292

2.31e-0491414914EFO_0004532
Diseaselevel of Phosphatidylethanolamine (16:0_18:2) in blood serum

MAP4K5 RAB3IL1 MUSK

2.36e-04241493OBA_2045136
DiseasecGMP-specific 3',5'-cyclic phosphodiesterase measurement

PDE5A C7

2.51e-0451492EFO_0008081
DiseaseDiGeorge syndrome (is_implicated_in)

DVL1P1 DVL1

2.51e-0451492DOID:11198 (is_implicated_in)
Diseaselysophosphatidylethanolamine 18:2 measurement

MAP4K5 RAB3IL1 MUSK

3.01e-04261493EFO_0010369
DiseaseProstatic Neoplasms

SELENOP ERG GALNT3 ARHGEF5 ICAM1 IVNS1ABP JAK1 JMJD6 ROBO1 CTSB ZNF292

3.09e-0461614911C0033578
DiseaseMalignant neoplasm of prostate

SELENOP ERG GALNT3 ARHGEF5 ICAM1 IVNS1ABP JAK1 JMJD6 ROBO1 CTSB ZNF292

3.09e-0461614911C0376358
Diseasedocosapentaenoic acid measurement

MAP4K5 RAB3IL1 MUSK

3.38e-04271493EFO_0006809
Diseasedietary heme iron intake measurement, type 2 diabetes mellitus

SVEP1 MUSK

3.75e-0461492EFO_0008355, MONDO_0005148
Diseaseintercellular adhesion molecule 4 measurement

ICAM1 CR1

3.75e-0461492EFO_0801708
Diseasetriacylglycerol 56:7 measurement

AHCTF1 MAP4K5 MUSK

4.19e-04291493EFO_0010434
DiseaseL-Selectin measurement

SELL SELENOP MAP4K5

5.11e-04311493EFO_0008202
DiseaseAmelogenesis imperfecta local hypoplastic form

LAMA3 RELT

5.23e-0471492C0399367
Diseaselevel of Phosphatidylcholine (18:2_20:3) in blood serum

RAB3IL1 MUSK

5.23e-0471492OBA_2045108
Diseasephosphatidylcholine 35:5 measurement

RAB3IL1 MUSK

5.23e-0471492EFO_0021472
Diseaseopioid-binding protein/cell adhesion molecule measurement

MAP4K5 C7

6.95e-0481492EFO_0020618
Diseasepimeloylcarnitine/3-methyladipoylcarnitine (C7-DC) measurement

THEM4 SLC22A1

6.95e-0481492EFO_0800494
Disease1-stearoyl-2-docosapentaenoyl-GPC (18:0/22:5n3) measurement

MAP4K5 MUSK

6.95e-0481492EFO_0800455
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 4 measurement

PSAP CTSB

6.95e-0481492EFO_0801768
Diseasebipolar I disorder

CACNA1C CUBN STARD9 PIGW MUSK

7.65e-041411495EFO_0009963
DiseaseMental deterioration

CACNA1C CR1

8.91e-0491492C0234985
DiseaseMild cognitive disorder

CACNA1C CR1

8.91e-0491492C1270972
Diseasephosphatidylcholine 39:5 measurement

RAB3IL1 MUSK

8.91e-0491492EFO_0021476
Diseaselevel of Phosphatidylcholine (O-18:1_18:2) in blood serum

RAB3IL1 MUSK

8.91e-0491492OBA_2045129
Diseaselevel of Phosphatidylcholine (18:0_20:5) in blood serum

RAB3IL1 MUSK

8.91e-0491492OBA_2045095
Diseasetriglyceride measurement, C-reactive protein measurement

MAP4K5 CTSB MUSK

9.35e-04381493EFO_0004458, EFO_0004530
Diseaselysophosphatidylcholine 20:3 measurement

MAP4K5 PARN MUSK

1.09e-03401493EFO_0010362
Disease1-palmitoyl-2-oleoyl-GPE (16:0/18:1) measurement

MAP4K5 MUSK

1.11e-03101492EFO_0800608
Diseasegamma-glutamylthreonine measurement

MAP4K5 ADGRE1

1.11e-03101492EFO_0021143
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [1] measurement

MAP4K5 MUSK

1.11e-03101492EFO_0800507
Diseasecholesteryl ester 22:4 measurement

RAB3IL1 MUSK

1.11e-03101492EFO_0021443
Diseaserheumatoid arthritis, systemic lupus erythematosus

UBE2L3 TNPO3

1.11e-03101492EFO_0000685, MONDO_0007915
Diseaseplatelet crit

CACNA1C POGLUT3 ERG TTC28 RNPEPL1 CUBN JAK1 GFI1B MAP4K5 PDE5A TNPO3 KCNQ1DN HEATR3

1.12e-0395214913EFO_0007985
Diseaselipid measurement, lipoprotein measurement

UBE2L3 MAP4K5 SLC22A1 CTSB

1.14e-03901494EFO_0004529, EFO_0004732
Diseaselysophosphatidylethanolamine measurement

MAP4K5 RAB3IL1 MUSK

1.17e-03411493EFO_0010225
Diseasemyocardial infarction (biomarker_via_orthology)

DVL1P1 ICAM1 DVL1 C7 CTSB

1.34e-031601495DOID:5844 (biomarker_via_orthology)
Disease1-stearoyl-2-oleoyl-GPE (18:0/18:1) measurement

MAP4K5 MUSK

1.35e-03111492EFO_0800269
Diseaselevel of Sterol ester (27:1/20:5) in blood serum

RAB3IL1 MUSK

1.35e-03111492OBA_2045197
Diseaselysophosphatidylcholine 20:2 measurement

RAB3IL1 MUSK

1.35e-03111492EFO_0021458
Diseaseretinopathy of prematurity (biomarker_via_orthology)

ICAM1 KDR

1.62e-03121492DOID:13025 (biomarker_via_orthology)
Diseasehyperhomocysteinemia (biomarker_via_orthology)

ICAM1 GPX1

1.62e-03121492DOID:9279 (biomarker_via_orthology)
Diseasephosphatidylcholine 34:4 measurement

MAP4K5 MUSK

1.62e-03121492EFO_0010378
Diseasetriacylglycerol 53:2 measurement

MAP4K5 MUSK

1.62e-03121492EFO_0021484
Disease1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement

MAP4K5 MUSK

1.62e-03121492EFO_0800453
Diseaselevel of Phosphatidylcholine (16:0_20:2) in blood serum

MAP4K5 MUSK

1.62e-03121492OBA_2045074
Diseasetriacylglycerol 54:4 measurement

MAP4K5 ATF7IP2 MUSK

1.63e-03461493EFO_0010422
Diseasephosphatidylethanolamine measurement

RNPEPL1 MAP4K5 GADL1 RAB3IL1 MUSK

1.90e-031731495EFO_0010228
Diseasehematologic cancer (implicated_via_orthology)

UBA2 JAK1

1.90e-03131492DOID:2531 (implicated_via_orthology)
Diseasefatty acid measurement, fetal genotype effect measurement, breast milk measurement

ZNF804B MUSK

1.90e-03131492EFO_0005110, EFO_0007959, EFO_0009092
Diseasephosphatidylcholine 40:7 measurement

ADAM23 MUSK

1.90e-03131492EFO_0021477
Diseaselevel of Phosphatidylcholine (O-16:0_20:4) in blood serum

RAB3IL1 MUSK

1.90e-03131492OBA_2045116
Diseasepre-eclampsia (implicated_via_orthology)

ICAM1 PDE5A

1.90e-03131492DOID:10591 (implicated_via_orthology)
Diseaselevel of Phosphatidylcholine (16:0_18:3) in blood serum

MAP4K5 MUSK

1.90e-03131492OBA_2045072
Diseaselevel of Phosphatidylcholine (16:1_18:1) in blood serum

MAP4K5 MUSK

1.90e-03131492OBA_2045082
Diseasecholesteryl ester 20:3 measurement

PARN RAB3IL1 MUSK

1.96e-03491493EFO_0010347
Diseasebody mass index, fasting blood glucose measurement

CRY2 MAP4K5 MUSK

2.20e-03511493EFO_0004340, EFO_0004465
DiseaseImpaired cognition

CACNA1C CR1

2.21e-03141492C0338656
Diseasefatty acid measurement, breast milk measurement, parental genotype effect measurement

ZNF804B MUSK

2.21e-03141492EFO_0005110, EFO_0005939, EFO_0009092
Diseaselevel of Phosphatidylethanolamine (18:1_18:1) in blood serum

RAB3IL1 MUSK

2.21e-03141492OBA_2045142
Diseaselevel of Phosphatidylethanolamine (18:2_0:0) in blood serum

MAP4K5 MUSK

2.21e-03141492OBA_2045143
Diseasediacylglycerol 38:4 measurement

RAB3IL1 MUSK

2.21e-03141492EFO_0020066
DiseaseDupuytren Contracture

ERG LRRK1 BOP1 KDR

2.23e-031081494EFO_0004229
Diseaseepisodic memory

SEMA3C ATF7IP2 BACE2

2.33e-03521493EFO_0004333
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement

RAB3IL1 MUSK

2.55e-03151492EFO_0800508
Diseaselevel of Triacylglycerol (53:3) in blood serum

MAP4K5 MUSK

2.55e-03151492OBA_2045165
Diseasebipolar disorder

CACNA1C RNPEPL1 SVEP1 GFI1B STARD9 RPTOR PDE5A DLEC1 MUSK

2.73e-035771499MONDO_0004985
DiseaseMalaria, susceptibility to

ICAM1 CR1

2.90e-03161492cv:C1970028
Diseaseendometriosis (biomarker_via_orthology)

SELL KDR

2.90e-03161492DOID:289 (biomarker_via_orthology)
Diseasephosphatidylcholine 32:2 measurement

MAP4K5 MUSK

2.90e-03161492EFO_0010374
Disease

ICAM1 CR1

2.90e-03161492611162
Diseaselevel of Phosphatidylcholine (18:0_18:2) in blood serum

RAB3IL1 MUSK

2.90e-03161492OBA_2045090
Diseaselevel of Phosphatidylcholine (18:0_20:3) in blood serum

PARN MUSK

2.90e-03161492OBA_2045093
DiseaseUremia

ICAM1 KDR

3.28e-03171492C0041948
Diseaselevel of Phosphatidylcholine (14:0_18:2) in blood serum

MAP4K5 MUSK

3.28e-03171492OBA_2045063
Diseasephosphatidylcholine measurement

PLEKHH1 UBE2L3 MAP4K5 PARN RAB3IL1 MUSK

3.29e-032841496EFO_0010226
Diseaseomega-6 polyunsaturated fatty acid measurement

UBE2L3 MAP4K5 SLC22A1 CTSB MUSK

3.32e-031971495EFO_0005680
Diseasemultiple myeloma (is_implicated_in)

ICAM1 GPX1 ROBO1

3.34e-03591493DOID:9538 (is_implicated_in)
Diseaserespiratory syncytial virus infectious disease (is_marker_for)

ICAM1 TLR8

3.67e-03181492DOID:1273 (is_marker_for)
Diseaselysophosphatidylcholine measurement

MAP4K5 RAB3IL1 MUSK

3.84e-03621493EFO_0010224
Diseaselysophosphatidylcholine 20:5 measurement

RAB3IL1 MUSK

4.09e-03191492EFO_0010364
Diseasediacylglycerol 38:5 measurement

RAB3IL1 MUSK

4.09e-03191492EFO_0020067
Diseasediacylglycerol 38:3 measurement

RAB3IL1 MUSK

4.09e-03191492EFO_0020065
Diseaseage at menopause

TTC28 SLCO4A1 BIRC6 UBE2L3 TNPO3 KPNA3

4.43e-033021496EFO_0004704
Diseasepolyunsaturated fatty acid measurement

UBE2L3 MAP4K5 SLC22A1 CTSB

4.46e-031311494EFO_0010733
DiseaseMalaria

ICAM1 CR1

4.53e-03201492C0024530
Diseasecoagulation factor V measurement

SELENOP MUSK

4.53e-03201492EFO_0008087
Diseasetotal lipids in very large HDL measurement

PIGT MAP4K5 MUSK

4.58e-03661493EFO_0022312
Diseasemagnesium measurement

TTC28 CCDC168 DLEC1

4.58e-03661493EFO_0004845
Diseasephospholipids in very large HDL measurement

PIGT MAP4K5 MUSK

4.58e-03661493EFO_0022298
Diseasefree cholesterol in large VLDL measurement

MAP4K5 SLC22A1 MUSK

4.98e-03681493EFO_0022265
Diseaselevel of Phosphatidylcholine (16:1_18:2) in blood serum

MAP4K5 MUSK

4.99e-03211492OBA_2045083

Protein segments in the cluster

PeptideGeneStartEntry
LNPPSSNWEVEKLSC

AZI2

151

Q9H6S1
VVKSVAWNPSPAVCL

BOP1

456

Q14137
NCVPAQSLSEPILWI

BACE2

456

Q9Y5Z0
SKLTEVPRVCAKPWA

CDCA5

186

Q96FF9
PWDSLLTRCLEKLQP

EIF2D

456

P41214
KPNTPLESRISKQWC

ELMOD1

146

Q8N336
NLGIQWEPSSRKPKC

ADAM23

436

O75077
WNSVFPKPGTLVQCL

BIRC6

706

Q9NR09
AREQWPQCPTIKEIR

CTSB

86

P07858
LRCIISGQPKPEVTW

ALPK2

31

Q86TB3
AKTRPACQDWTVPLP

ARHGEF5

876

Q12774
DPKLITWSPVCRNDV

GPX1

146

P07203
WLSQPPARVTIKMEC

ERG

56

P11308
EVLPGWTSCVIKDNP

ASB15

466

Q8WXK1
WVPLLSRILPSDACK

ANKRD13C

236

Q8N6S4
VSCKQTEVPLSVPWD

ACOT11

366

Q8WXI4
ESCPAPLTTWRQKRE

CAMSAP1

846

Q5T5Y3
LQSCLPKEWLTPAAL

DESI2

141

Q9BSY9
PIVLTVAKCWDPSPQ

DVL2

346

O14641
PSVRNVEVPEWTKCS

AP3B2

651

Q13367
TRPCPSWKAVRVDLV

POLM

406

Q9NP87
LAAVPVPWKSTDPCQ

RAB3IL1

16

Q8TBN0
SKCLQWLQPRDSTSP

ANKRD33

381

Q7Z3H0
GWQLTCVLPTPVVKT

RFTN1

401

Q14699
IPWIAPECVEDSKNL

JAK1

756

P23458
WKEADSKRLNPQCIP

PARN

531

O95453
EKQRWISALCPSSPQ

ARHGEF19

691

Q8IW93
EFTSWVPLVSKICPS

ANKRD13B

136

Q86YJ7
TDDTPIKRCLQTKWP

MINDY3

416

Q9H8M7
LPLWRERPQKTASNC

PRSS12

751

P56730
TWVIVNLCRNKDPPP

KPNA3

221

O00505
WCLFPTSTPRELIKV

JMJD6

206

Q6NYC1
SCKITGRPQPQVTWL

MYLK

181

Q15746
SVKVWQDACSPLPKT

LAMA3

2966

Q16787
WTTPSLKCIRDPALV

IL15RA

86

Q13261
PNTDCSLPTKVFWIA

MBTD1

181

Q05BQ5
EKNPGVWLNTTQPLC

MBD3

201

O95983
DPVTKLWTSCAPLNI

IVNS1ABP

486

Q9Y6Y0
TPAKTEICPWEVNER

GPR179

1586

Q6PRD1
AETCPWEVTERIPVK

GPR179

2016

Q6PRD1
GWCAINSKILVPPRT

L3MBTL2

271

Q969R5
AALPPQEKWTCRQLK

LRRK1

486

Q38SD2
PNQCLDWTNLKREPE

GFI1B

51

Q5VTD9
EKCPTLNGQPQWSAL

KCNQ1DN

46

Q9H478
KLQTPKEEVSWPCPQ

CFAP65

1591

Q6ZU64
LLKQTRPVQSWLCDP

CAND1

401

Q86VP6
ELDLPNRKIWPTECQ

CFAP52

186

Q8N1V2
SVPPTDKVCLWLGAN

VBP1

116

P61758
DTARTWLPTQPQRKC

PCSK4

441

Q6UW60
TACDLSAITKPWPIQ

PDE5A

761

O76074
RCPNPTKQIWTVNEA

HERC4

391

Q5GLZ8
LNTWELSEGTNCPPK

COPRS

91

Q9NQ92
QCVESSPLVPIQQEW

DNAH12

101

Q6ZR08
VKNPEWSRNEIPHSC

NFX1

426

Q12986
PIKLPCNSENVTWLK

KIF24

1241

Q5T7B8
CNSENVTWLKPRPIS

KIF24

1246

Q5T7B8
SGIWSNPSPICQKLD

SELL

306

P14151
VPLKCLAQEVNIPDW

LAS1L

136

Q9Y4W2
KWICDNIEITPTPAQ

PRSS38

286

A1L453
RLQTIWKEEPIPCTA

NQO2

211

P16083
CEVKGDPTPTIQWNR

HMCN1

4371

Q96RW7
CKVSGLPTPDLSWQL

PALLD

1156

Q8WX93
RLTEPVVPKDWQQEC

ACP2

356

P11117
CPSPTDRAQWLEKTQ

PLEKHG6

491

Q3KR16
CTWVIDSPPHQQVKI

CUBN

3306

O60494
QFWPLVEIQCSPDLK

FZD8

71

Q9H461
PPTCIQLLDSSNWKE

CKAP5

601

Q14008
IAVDLCSRNPTWKPL

HEATR3

441

Q7Z4Q2
NPIRRACISIVEWKP

CACNA1C

111

Q13936
AQIIVLWNCDKPLPA

EXT1

511

Q16394
QALNKWEPELPSCSR

CR1

281

P17927
QALNKWEPELPSCSR

CR1

731

P17927
QALNKWEPELPSCSR

CR1

1181

P17927
PWNAPESIQKAAKCI

CRY2

466

Q49AN0
VQNWLVEVPTVSPIC

ERVK-6

176

Q69384
VTFLAPVTWPDKVVC

FAHD2B

96

Q6P2I3
PVVHCDINVPSKWQT

DCDC2C

116

A8MYV0
VSCNPSDPLQKWILS

GALNT3

616

Q14435
IVVQVPSTWCLKEDP

GARRE1

446

O15063
KENPLTQAVPKCQRW

C7

691

P10643
EFPCLPKQVAWILAT

GON4L

786

Q3T8J9
DKLPSQPKEVQTLWC

C1orf112

351

Q9NSG2
IPSCQDWKDISVPTL

CALHM4

266

Q5JW98
SPANSCPQIQKLWSI

C19orf67

271

A6NJJ6
SICISIPPLFWRQAK

HTR1D

166

P28221
AQLPPGEKLTCWQAV

DRC7

756

Q8IY82
WNITKINPKCAPVES

ATF7IP2

596

Q5U623
QWERIDCQGIPPSSK

KLHDC2

131

Q9Y2U9
ISLTVAKCWDPTPRS

DVL1

331

O14640
LPSWQPVGKNLTLRC

ICAM1

121

P05362
TTPKKCAVPVETEWL

AHCTF1

1256

Q8WYP5
VCEWRPPEQLKQLLD

GADL1

71

Q6ZQY3
SCPKSRKLAPENWSV

CCDC168

81

Q8NDH2
QLNPSENCTWTIERP

CUZD1

51

Q86UP6
ISLTVAKCWDPTPRS

DVL1P1

331

P54792
PPVKSVSRWCIDSEL

DLEC1

186

Q9Y238
APPCTQRITWKGVLL

PSG4

6

Q00888
ANTECTWTINPPPKR

SCUBE2

831

Q9NQ36
CVPESPRWLLSQKRN

SLC22A1

281

O15245
PVPSNKTTCENWREI

BVES

26

Q8NE79
PNAPLSWVRACVQVL

CHID1

271

Q9BWS9
PLKINCATSWIHPDT

MAP4K5

506

Q9Y4K4
RILLWDTRCPKPASQ

WDR77

191

Q9BQA1
PPVSQCVQWVDEAKL

RSBN1

641

Q5VWQ0
DVLQSLPPAWRNCVS

STK11IP

906

Q8N1F8
RVWAEPCLLPTATSK

RNPEPL1

276

Q9HAU8
PITLKRPICKDNWQA

SPDYA

31

Q5MJ70
SPVSLELTPKDQCWV

PRSS29P

181

A6NIE9
CQPRSPQATVKWLFQ

SEMA3F

626

Q13275
ECAPKSPQASIKWLL

SEMA3C

591

Q99985
EVVPEWASCLKSPRI

SYNPO

691

Q8N3V7
NKWIGEIRSNLPCTP

RHOH

96

Q15669
WSLIKNTCPPKDDPQ

PRR3

136

P79522
TPPNLLAKELWSSCT

SMG1

2291

Q96Q15
CVDPWLTQTRKTCPI

RNF167

256

Q9H6Y7
RNTPSEPIHCIVWAK

UBA2

176

Q9UBT2
PGQAVDCIWTIKATP

NETO2

201

Q8NC67
WTSQPPLCKVTQTTD

SEZ6L2

821

Q6UXD5
RLKHTCSPQEDSPWQ

STARD9

3196

Q9P2P6
TPLSPVEIECAKWLQ

HERC2P3

51

Q9BVR0
RENIPEWKNCIIVSP

PRPS1L1

156

P21108
DWCRSPPPVQVSEKV

SVEP1

651

Q4LDE5
SLCKQPPAWSIRDQD

SELENOP

26

P49908
VKTTPCARLECWIDP

RPTOR

76

Q8N122
LVPCSWKLIQSPVTN

PIGW

406

Q7Z7B1
PLDTSKQPLCQLWAE

SLCO4A1

51

Q96BD0
PKQKFERPICVSWST

ADGRE1

541

Q14246
DPQAWQKTLSCPTKE

POGLUT3

146

Q7Z4H8
ICKSSILQWPDNPKA

TLR8

996

Q9NR97
QWPTELLLFTKTEPC

ZNF804B

456

A4D1E1
LPREVVCTENLTPWK

PIGT

176

Q969N2
PCEVWLPFLQSLQES

RLF

146

Q13129
CLPVISAENWKPATK

UBE2L5

86

A0A1B0GUS4
VILKDCSVPNPSWNK

THEM4

41

Q5T1C6
CSVPNPSWNKDLRLL

THEM4

46

Q5T1C6
SQDCTVKLWPLPKAL

TBL3

441

Q12788
PPCVNKVSDWKLEIL

TNFSF18

76

Q9UNG2
PSPQAIWSITCKGDI

TECPR1

726

Q7Z6L1
KPDLITCLEQNKEPW

ZNF679

61

Q8IYX0
WKNPVLCTILSQEPL

ZNF292

161

O60281
PCITLKNWVQTLRPV

TPP2

786

P29144
CVATGSPVPTILWRK

ROBO1

476

Q9Y6N7
TVWNKPTVKSLPCDI

PSAP

51

P07602
LTTKWATLQGCSPPE

PLEKHH1

1196

Q9ULM0
EITIDPTCSWKPVPV

ZMIZ2

671

Q8NF64
LPIDAVQWDICNLPL

THUMPD3

381

Q9BV44
THPCQKVIQEIWPVL

TNPO3

631

Q9Y5L0
ANEFPCLPKQVAWIL

YY1AP1

261

Q9H869
VELRLPHCDPKTWQN

TJP1

1711

Q07157
SRCSQKKWPEVLLSP

RELT

296

Q969Z4
QCVLVSLWPVPVAAS

TTC28

1651

Q96AY4
PAVPWKDLTCLRASQ

ZNF397

146

Q8NF99
DPWIINAKISRQSCP

ZNF26

71

P17031
LECLPKSPQAAVRWL

SEMA3G

601

Q9NS98
GELPTPVCKNLDTLW

KDR

596

P35968
RGPVNTIQWCPVLSK

WDR25

246

Q64LD2
TWPLPLSTDQCIKSN

SLC5A12

466

Q1EHB4
NIPTWLTELGKTCPF

TRIP12

1526

Q14669
LDCLTQATPKPTVVW

PTK7

431

Q13308
LEWCIQQSSNPIPKR

ZFYVE26

416

Q68DK2
PWPLRPTNSEETCIK

SOCS6

136

O14544
PELLRVTWAPGLKNC

WDR73

276

Q6P4I2
KPWLLEVNLSPSLAC

TTLL5

361

Q6EMB2
CLPVISAENWKPATK

UBE2L3

86

P68036
GSPDWAQVPCLQKRT

PIFO

151

Q8TCI5
ECLAKGTPAPQISWI

MXRA5

1971

Q9NR99
WNELKVVSPVCRPAA

MUSK

356

O15146