Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coregulator activity	BHLHE41 KMT2C KMT2D YAP1 PAWR SIN3A MAML2 KAT2A SRCAP ARID5A	1.28e-05	562	65	10	GO:0003712
GeneOntologyMolecularFunction	WW domain binding	NFE2 TNK2 DNM2	7.19e-05	25	65	3	GO:0050699
GeneOntologyMolecularFunction	transcription factor binding	BHLHE41 UBN1 YAP1 SREBF1 PRDM13 SIN3A KAT2A TAF4 RUNX2 ARID5A	1.50e-04	753	65	10	GO:0008134
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2D	2.88e-04	8	65	2	GO:0140945
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	BHLHE41 KMT2C KMT2D YAP1 TICAM1 PAWR SIN3A MAML2 KAT2A SRCAP ARID5A NUFIP1	3.21e-04	1160	65	12	GO:0030674
GeneOntologyMolecularFunction	acetyltransferase activity	FASN LPCAT2 KAT2A SRCAP	3.68e-04	104	65	4	GO:0016407
GeneOntologyMolecularFunction	transcription coactivator activity	KMT2C KMT2D YAP1 MAML2 KAT2A SRCAP	4.53e-04	303	65	6	GO:0003713
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2D	4.62e-04	10	65	2	GO:0140999
GeneOntologyMolecularFunction	protein domain specific binding	HOXA3 SCAF1 ZNF384 NFE2 TNK2 PAWR RUNX2 SRRM2 ARHGEF16 DNM2	4.98e-04	875	65	10	GO:0019904
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	BHLHE41 YAP1 PRDM13 SIN3A KAT2A TAF4 RUNX2 ARID5A	5.81e-04	582	65	8	GO:0140297
GeneOntologyMolecularFunction	histone modifying activity	KMT2C KMT2D PRDM13 KAT2A SRCAP	8.96e-04	229	65	5	GO:0140993
GeneOntologyMolecularFunction	transcription corepressor activity	BHLHE41 YAP1 PAWR SIN3A ARID5A	8.96e-04	229	65	5	GO:0003714
GeneOntologyMolecularFunction	molecular adaptor activity	BHLHE41 KMT2C KMT2D YAP1 TICAM1 PAWR SIN3A MAML2 KAT2A SRCAP ARID5A NUFIP1	1.28e-03	1356	65	12	GO:0060090
GeneOntologyMolecularFunction	histone methyltransferase activity	KMT2C KMT2D PRDM13	1.61e-03	71	65	3	GO:0042054
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2C KMT2D	1.91e-03	20	65	2	GO:0042800
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXA3 BHLHE41 ZNF384 EBF3 NFE2 YAP1 SREBF1 SOX18 RUNX2 FOXI3 TFE3	2.10e-03	1244	65	11	GO:0000978
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF384 KMT2D EBF3 SREBF1 SOX18 RUNX2 TFE3	2.24e-03	560	65	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF384 KMT2D EBF3 SREBF1 SOX18 RUNX2 TFE3	2.38e-03	566	65	7	GO:0001216
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HOXA3 BHLHE41 ZNF384 EBF3 NFE2 YAP1 SREBF1 SOX18 RUNX2 FOXI3 TFE3	2.48e-03	1271	65	11	GO:0000987
GeneOntologyMolecularFunction	dopamine receptor binding	PALM DNM2	3.22e-03	26	65	2	GO:0050780
GeneOntologyMolecularFunction	protein methyltransferase activity	KMT2C KMT2D PRDM13	4.62e-03	103	65	3	GO:0008276
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXA3 BHLHE41 ZNF384 KMT2D EBF3 NFE2 SREBF1 SOX18 RUNX2 FOXI3 TFE3	5.53e-03	1412	65	11	GO:0000981
GeneOntologyMolecularFunction	bHLH transcription factor binding	BHLHE41 RUNX2	6.46e-03	37	65	2	GO:0043425
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXA3 BHLHE41 ZNF384 EBF3 NFE2 YAP1 SREBF1 SOX18 RUNX2 FOXI3 TFE3	7.04e-03	1459	65	11	GO:0000977
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	FASN LPCAT2 KAT2A SRCAP	7.55e-03	238	65	4	GO:0016747
GeneOntologyBiologicalProcess	actin cytoskeleton organization	PDLIM7 FRMD7 KANK4 TRIOBP FHOD3 PAWR RFLNA ASB2 DMTN DNM2 SMTNL2 CDC42EP1	6.74e-06	803	65	12	GO:0030036
GeneOntologyBiologicalProcess	cartilage development	HOXA3 KAT2A RFLNA SIK3 RUNX2 ARID5A COL1A1	1.12e-05	243	65	7	GO:0051216
GeneOntologyBiologicalProcess	actin filament-based process	PDLIM7 FRMD7 KANK4 TRIOBP FHOD3 PAWR RFLNA ASB2 DMTN DNM2 SMTNL2 CDC42EP1	2.40e-05	912	65	12	GO:0030029
GeneOntologyBiologicalProcess	actin filament organization	FRMD7 KANK4 TRIOBP FHOD3 PAWR RFLNA DMTN DNM2 CDC42EP1	2.96e-05	509	65	9	GO:0007015
GeneOntologyBiologicalProcess	negative regulation of cytoskeleton organization	FRMD7 KANK4 TRIOBP FHOD3 KAT2A DMTN	3.34e-05	194	65	6	GO:0051494
GeneOntologyBiologicalProcess	actin filament bundle organization	FRMD7 KANK4 PAWR RFLNA DMTN DNM2	3.44e-05	195	65	6	GO:0061572
GeneOntologyBiologicalProcess	negative regulation of organelle organization	YAP1 FRMD7 KANK4 TRIOBP FHOD3 KAT2A DMTN DNM2	5.14e-05	421	65	8	GO:0010639
GeneOntologyBiologicalProcess	regulation of cellular component size	PTPRS KANK4 TRIOBP FHOD3 SIN3A DMTN DNM2 CDC42EP1	5.59e-05	426	65	8	GO:0032535
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	TRAPPC12 PTPRS YAP1 TICAM1 FRMD7 KANK4 TRIOBP PALM FHOD3 KAT2A DMTN DNM2 CDC42EP1	7.21e-05	1189	65	13	GO:0044087
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ZNF384 KMT2C KMT2D EBF3 YAP1 SREBF1 SOX18 MAML2 KAT2A TAF4 RUNX2 ARID5A TFE3 NUFIP1	8.81e-05	1390	65	14	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of actin filament polymerization	KANK4 TRIOBP FHOD3 DMTN	9.23e-05	75	65	4	GO:0030837
GeneOntologyBiologicalProcess	connective tissue development	HOXA3 KAT2A RFLNA SIK3 RUNX2 ARID5A COL1A1	1.01e-04	343	65	7	GO:0061448
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection assembly	YAP1 FRMD7 PALM DMTN DNM2 CDC42EP1	1.30e-04	248	65	6	GO:0120032
GeneOntologyBiologicalProcess	regulation of actin filament polymerization	KANK4 TRIOBP FHOD3 DMTN CDC42EP1	1.33e-04	156	65	5	GO:0030833
GeneOntologyBiologicalProcess	regulation of cell projection assembly	YAP1 FRMD7 PALM DMTN DNM2 CDC42EP1	1.39e-04	251	65	6	GO:0060491
GeneOntologyBiologicalProcess	negative regulation of protein polymerization	KANK4 TRIOBP FHOD3 DMTN	1.95e-04	91	65	4	GO:0032272
GeneOntologyBiologicalProcess	regulation of protein targeting	ERBB2 HTRA2 SREBF1 DMTN	2.12e-04	93	65	4	GO:1903533
GeneOntologyBiologicalProcess	regulation of actin polymerization or depolymerization	KANK4 TRIOBP FHOD3 DMTN CDC42EP1	2.40e-04	177	65	5	GO:0008064
GeneOntologyBiologicalProcess	regulation of organelle organization	HTRA2 TRAPPC12 PTPRS YAP1 FRMD7 SREBF1 KANK4 TRIOBP FHOD3 KAT2A DMTN DNM2 CDC42EP1	2.42e-04	1342	65	13	GO:0033043
GeneOntologyBiologicalProcess	regulation of actin filament length	KANK4 TRIOBP FHOD3 DMTN CDC42EP1	2.59e-04	180	65	5	GO:0030832
GeneOntologyBiologicalProcess	parathyroid gland development	HOXA3 FOXI3	2.70e-04	8	65	2	GO:0060017
GeneOntologyBiologicalProcess	actin filament polymerization	KANK4 TRIOBP FHOD3 DMTN CDC42EP1	3.32e-04	190	65	5	GO:0030041
GeneOntologyBiologicalProcess	replacement ossification	SIK3 RUNX2 COL1A1	3.37e-04	43	65	3	GO:0036075
GeneOntologyBiologicalProcess	endochondral ossification	SIK3 RUNX2 COL1A1	3.37e-04	43	65	3	GO:0001958
GeneOntologyBiologicalProcess	actin filament bundle assembly	FRMD7 KANK4 PAWR DMTN DNM2	3.40e-04	191	65	5	GO:0051017
GeneOntologyBiologicalProcess	negative regulation of cellular component organization	NFE2 PTPRS YAP1 FRMD7 KANK4 TRIOBP FHOD3 KAT2A DMTN DNM2	3.49e-04	864	65	10	GO:0051129
GeneOntologyBiologicalProcess	regulation of actin filament organization	FRMD7 KANK4 TRIOBP FHOD3 DMTN CDC42EP1	3.62e-04	300	65	6	GO:0110053
GeneOntologyBiologicalProcess	ossification	FASN NFE2 PDLIM7 YAP1 RFLNA SIK3 RUNX2 COL1A1	3.72e-04	562	65	8	GO:0001503
GeneOntologyBiologicalProcess	regulation of lamellipodium assembly	FRMD7 DMTN DNM2	3.86e-04	45	65	3	GO:0010591
GeneOntologyBiologicalProcess	negative regulation of supramolecular fiber organization	FRMD7 KANK4 TRIOBP FHOD3 DMTN	3.92e-04	197	65	5	GO:1902904
GeneOntologyBiologicalProcess	response to organic cyclic compound	KMT2D ZFP36L2 YAP1 TICAM1 SREBF1 PALM SIN3A KAT2A DMTN DNM2 COL1A1	3.97e-04	1048	65	11	GO:0014070
GeneOntologyBiologicalProcess	cellular response to epidermal growth factor stimulus	ERBB2 ZFP36L2 COL1A1	4.96e-04	49	65	3	GO:0071364
GeneOntologyBiologicalProcess	chordate embryonic development	HOXA3 KMT2D NFE2 YAP1 SOX18 SIN3A KAT2A RUNX2 FOXI3 COL1A1	5.07e-04	906	65	10	GO:0043009
GeneOntologyBiologicalProcess	regulation of stem cell proliferation	HOXA3 YAP1 SOX18 RUNX2	5.44e-04	119	65	4	GO:0072091
GeneOntologyBiologicalProcess	negative regulation of organelle assembly	YAP1 KAT2A DNM2	5.91e-04	52	65	3	GO:1902116
GeneOntologyBiologicalProcess	positive regulation of plasma membrane bounded cell projection assembly	FRMD7 PALM DNM2 CDC42EP1	6.16e-04	123	65	4	GO:0120034
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	HOXA3 KMT2D NFE2 YAP1 SOX18 SIN3A KAT2A RUNX2 FOXI3 COL1A1	6.17e-04	929	65	10	GO:0009792
GeneOntologyBiologicalProcess	protein polymerization	KANK4 TRIOBP FHOD3 DMTN DNM2 CDC42EP1	6.38e-04	334	65	6	GO:0051258
GeneOntologyBiologicalProcess	response to epidermal growth factor	ERBB2 ZFP36L2 COL1A1	6.61e-04	54	65	3	GO:0070849
GeneOntologyBiologicalProcess	actin polymerization or depolymerization	KANK4 TRIOBP FHOD3 DMTN CDC42EP1	6.75e-04	222	65	5	GO:0008154
GeneOntologyBiologicalProcess	regulation of anatomical structure size	PTPRS KANK4 TRIOBP FHOD3 SIN3A DMTN DNM2 CDC42EP1	6.96e-04	618	65	8	GO:0090066
GeneOntologyBiologicalProcess	ether lipid biosynthetic process	FASN LPCAT2	7.46e-04	13	65	2	GO:0008611
GeneOntologyBiologicalProcess	glycerol ether biosynthetic process	FASN LPCAT2	7.46e-04	13	65	2	GO:0046504
GeneOntologyBiologicalProcess	regulation of lamellipodium organization	FRMD7 DMTN DNM2	7.74e-04	57	65	3	GO:1902743
GeneOntologyBiologicalProcess	supramolecular fiber organization	FRMD7 KANK4 TRIOBP FHOD3 PAWR RFLNA DMTN DNM2 COL1A1 CDC42EP1	7.76e-04	957	65	10	GO:0097435
GeneOntologyBiologicalProcess	response to retinoic acid	HTRA2 YAP1 SREBF1 COL1A1	7.80e-04	131	65	4	GO:0032526
GeneOntologyBiologicalProcess	regulation of protein polymerization	KANK4 TRIOBP FHOD3 DMTN CDC42EP1	8.07e-04	231	65	5	GO:0032271
GeneOntologyBiologicalProcess	establishment of endothelial barrier	FASN PTPRS SOX18	8.14e-04	58	65	3	GO:0061028
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	HOXA3 YAP1 TRIOBP SOX18 RUNX2 ASB2	8.26e-04	351	65	6	GO:0048562
GeneOntologyBiologicalProcess	regulation of protein-containing complex assembly	TRAPPC12 TICAM1 KANK4 TRIOBP FHOD3 DMTN CDC42EP1	8.57e-04	489	65	7	GO:0043254
GeneOntologyBiologicalProcess	ether biosynthetic process	FASN LPCAT2	8.68e-04	14	65	2	GO:1901503
GeneOntologyBiologicalProcess	protein-DNA complex organization	KMT2C KMT2D UBN1 TRAPPC12 NFE2 PRDM13 SIN3A KAT2A TAF4 SRCAP	1.08e-03	999	65	10	GO:0071824
GeneOntologyBiologicalProcess	cellular response to dopamine	PALM SIN3A DNM2	1.08e-03	64	65	3	GO:1903351
GeneOntologyBiologicalProcess	response to dopamine	PALM SIN3A DNM2	1.19e-03	66	65	3	GO:1903350
GeneOntologyBiologicalProcess	regulation of substrate adhesion-dependent cell spreading	TRIOBP DMTN DNM2	1.19e-03	66	65	3	GO:1900024
GeneOntologyBiologicalProcess	establishment of endothelial intestinal barrier	FASN PTPRS	1.29e-03	17	65	2	GO:0090557
GeneOntologyBiologicalProcess	protein acetylation	NFE2 KAT2A ARID5A	1.29e-03	68	65	3	GO:0006473
GeneOntologyBiologicalProcess	cellular response to monoamine stimulus	PALM SIN3A DNM2	1.29e-03	68	65	3	GO:0071868
GeneOntologyBiologicalProcess	cellular response to catecholamine stimulus	PALM SIN3A DNM2	1.29e-03	68	65	3	GO:0071870
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	FRMD7 KANK4 TRIOBP FHOD3 DMTN CDC42EP1	1.31e-03	384	65	6	GO:0032956
GeneOntologyBiologicalProcess	positive regulation of protein acetylation	NFE2 ARID5A	1.45e-03	18	65	2	GO:1901985
GeneOntologyBiologicalProcess	bone development	KAT2A RFLNA SIK3 RUNX2 COL1A1	1.46e-03	264	65	5	GO:0060348
GeneOntologyBiologicalProcess	stem cell proliferation	HOXA3 YAP1 SOX18 RUNX2	1.49e-03	156	65	4	GO:0072089
GeneOntologyBiologicalProcess	cellular response to retinoic acid	HTRA2 YAP1 COL1A1	1.59e-03	73	65	3	GO:0071300
GeneOntologyBiologicalProcess	response to catecholamine	PALM SIN3A DNM2	1.59e-03	73	65	3	GO:0071869
GeneOntologyBiologicalProcess	embryo development	HOXA3 KMT2D NFE2 YAP1 TRIOBP SOX18 SIN3A KAT2A RUNX2 ASB2 FOXI3 COL1A1	1.59e-03	1437	65	12	GO:0009790
GeneOntologyCellularComponent	transcription regulator complex	BHLHE41 NFE2 YAP1 SOX18 SIN3A KAT2A TAF4 RUNX2 ARID5A TFE3	2.16e-05	596	68	10	GO:0005667
GeneOntologyCellularComponent	chromatin	HOXA3 BHLHE41 HTRA2 EBF3 NFE2 SREBF1 SOX18 PAWR SIN3A KAT2A TAF4 RUNX2 SRCAP TFE3 NUFIP1	6.53e-05	1480	68	15	GO:0000785
GeneOntologyCellularComponent	actin cytoskeleton	PDLIM7 TRIOBP FHOD3 PAWR RFLNA ASB2 DMTN DNM2 SMTNL2	9.97e-05	576	68	9	GO:0015629
GeneOntologyCellularComponent	anchoring junction	ZNF384 GJA4 UBN1 PDLIM7 YAP1 PPFIBP1 TRIOBP TNK2 MAST2 DNM2 CDC42EP1	2.90e-04	976	68	11	GO:0070161
GeneOntologyCellularComponent	MLL3/4 complex	KMT2C KMT2D	6.74e-04	12	68	2	GO:0044666
Domain	FYrich_C	KMT2C KMT2D	1.15e-04	5	64	2	IPR003889
Domain	FYrich_N	KMT2C KMT2D	1.15e-04	5	64	2	IPR003888
Domain	FYRC	KMT2C KMT2D	1.15e-04	5	64	2	SM00542
Domain	FYRN	KMT2C KMT2D	1.15e-04	5	64	2	SM00541
Domain	FYRN	KMT2C KMT2D	1.15e-04	5	64	2	PF05964
Domain	FYRC	KMT2C KMT2D	1.15e-04	5	64	2	PF05965
Domain	FYRC	KMT2C KMT2D	1.15e-04	5	64	2	PS51543
Domain	FYRN	KMT2C KMT2D	1.15e-04	5	64	2	PS51542
Domain	SET	KMT2C KMT2D PRDM13	5.24e-04	46	64	3	SM00317
Domain	SET_dom	KMT2C KMT2D PRDM13	6.70e-04	50	64	3	IPR001214
Domain	SET	KMT2C KMT2D PRDM13	6.70e-04	50	64	3	PS50280
Domain	HLH	BHLHE41 EBF3 SREBF1 TFE3	6.74e-04	116	64	4	SM00353
Domain	HMG_box	KMT2C KMT2D SOX18	7.96e-04	53	64	3	PF00505
Domain	HMG	KMT2C KMT2D SOX18	8.40e-04	54	64	3	SM00398
Domain	Post-SET_dom	KMT2C KMT2D	1.34e-03	16	64	2	IPR003616
Domain	PostSET	KMT2C KMT2D	1.34e-03	16	64	2	SM00508
Domain	POST_SET	KMT2C KMT2D	1.34e-03	16	64	2	PS50868
Domain	HMG_box_dom	KMT2C KMT2D SOX18	1.44e-03	65	64	3	IPR009071
Domain	CRIB	TNK2 CDC42EP1	2.11e-03	20	64	2	PS50108
Domain	CRIB_dom	TNK2 CDC42EP1	2.33e-03	21	64	2	IPR000095
Domain	EPHD	KMT2C KMT2D	2.55e-03	22	64	2	PS51805
Domain	AT_hook	KMT2C SRCAP	3.84e-03	27	64	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2C SRCAP	3.84e-03	27	64	2	IPR017956
Domain	-	BHLHE41 SREBF1 TFE3	6.22e-03	109	64	3	4.10.280.10
Domain	HLH	BHLHE41 SREBF1 TFE3	6.54e-03	111	64	3	PF00010
Pathway	REACTOME_RUNX2_REGULATES_OSTEOBLAST_DIFFERENTIATION	YAP1 RUNX2 COL1A1	7.13e-05	24	48	3	M27803
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1	KMT2C KMT2D NFE2 YAP1 SIN3A RUNX2	1.44e-04	237	48	6	M27786
Pathway	REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT	YAP1 RUNX2 COL1A1	1.56e-04	31	48	3	M27805
Pathway	PID_SMAD2_3NUCLEAR_PATHWAY	SIN3A KAT2A RUNX2 TFE3	1.70e-04	82	48	4	M2
Pathway	REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION	KMT2C KMT2D NFE2 SIN3A	3.12e-04	96	48	4	M27792
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2C KMT2D KAT2A	3.87e-04	42	48	3	M48018
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS	FASN SREBF1	4.03e-04	9	48	2	M29789
Pathway	WP_LIVER_X_RECEPTOR_PATHWAY	FASN SREBF1	5.02e-04	10	48	2	M39557
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	MAML2 KAT2A	5.02e-04	10	48	2	MM15535
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SCAF1 ZNF384 KMT2C ERBB2 KIAA0930 FASN KMT2D MAN2A2 TBKBP1 UBN1 ZFP36L2 TRAPPC12 PTPRS SREBF1 PALM TNK2 ZFYVE26 KAT2A SRCAP MAST2 TFE3 COL1A1	9.03e-17	1105	68	22	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ERBB2 KIAA0930 ZFP36L2 YAP1 PPFIBP1 SIK2 SIK3 MAST2 SRRM2 ARHGEF16 DMTN CDC42EP1	1.00e-07	861	68	12	36931259
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXA3 BHLHE41 ZNF384 KMT2D ZFP36L2 EBF3 NFE2 SREBF1 SOX18 RUNX2 FOXI3 TFE3	1.77e-07	908	68	12	19274049
Pubmed	Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.	ZNF384 SIN3A KAT2A COL1A1	1.93e-07	26	68	4	26244796
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KIAA0930 TBKBP1 ZFP36L2 PDLIM7 YAP1 PPFIBP1 MAST2 DMTN CDC42EP1	2.18e-07	446	68	9	24255178
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	KMT2C ERBB2 UBN1 TRAPPC12 PPFIBP1 MAML2 TAF4 SIK3 MAST2 NUFIP1	9.02e-07	689	68	10	36543142
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SCAF1 ERBB2 C16orf96 SIN3A KAT2A TAF4 SIK3 SRCAP MAST2 SRRM2 NUFIP1 CDC42EP1	1.56e-06	1116	68	12	31753913
Pubmed	Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation.	YAP1 RUNX2 COL1A1	2.02e-06	13	68	3	25746793
Pubmed	High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms.	SIK2 SIK3	3.77e-06	2	68	2	31849250
Pubmed	Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs.	ERBB2 FASN	3.77e-06	2	68	2	26107737
Pubmed	Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy.	YAP1 COL1A1	3.77e-06	2	68	2	23544078
Pubmed	Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma.	YAP1 TFE3	3.77e-06	2	68	2	23737213
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	3.77e-06	2	68	2	31924266
Pubmed	Interaction between fatty acid synthase and human epidermal growth receptor 2 (HER2) in osteosarcoma cells.	ERBB2 FASN	3.77e-06	2	68	2	25674245
Pubmed	Recurrent YAP1::MAML2 fusions in "nodular necrotizing" variants of myxoinflammatory fibroblastic sarcoma: a comprehensive study of 7 cases.	YAP1 MAML2	3.77e-06	2	68	2	35546636
Pubmed	Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.	ERBB2 FASN	3.77e-06	2	68	2	27714708
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	3.77e-06	2	68	2	28967912
Pubmed	Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.	ERBB2 FASN	3.77e-06	2	68	2	15235125
Pubmed	YAP1-TFE3-fused hemangioendothelioma: a multi-institutional clinicopathologic study of 24 genetically-confirmed cases.	YAP1 TFE3	3.77e-06	2	68	2	34381186
Pubmed	Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2.	FASN SREBF1	3.77e-06	2	68	2	18420801
Pubmed	Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes.	SIK2 SIK3	3.77e-06	2	68	2	27807598
Pubmed	Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals.	FASN SREBF1	3.77e-06	2	68	2	12897158
Pubmed	Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cells.	FASN SREBF1	3.77e-06	2	68	2	22786746
Pubmed	Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses.	SIK2 SIK3	3.77e-06	2	68	2	31969556
Pubmed	Differential expression of fatty acid synthase (FAS) and ErbB2 in nonmalignant and malignant oral keratinocytes.	ERBB2 FASN	3.77e-06	2	68	2	18528705
Pubmed	Sulphur dioxide and fluoride co-exposure induce incisor hypomineralization and amelogenin upregulation via YAP/RUNX2 signaling pathway.	YAP1 RUNX2	3.77e-06	2	68	2	36155332
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	3.77e-06	2	68	2	36601880
Pubmed	Nmp4/CIZ suppresses parathyroid hormone-induced increases in trabecular bone.	ZNF384 COL1A1	3.77e-06	2	68	2	19189321
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	3.77e-06	2	68	2	28483418
Pubmed	Recurrent YAP1 and MAML2 Gene Rearrangements in Retiform and Composite Hemangioendothelioma.	YAP1 MAML2	3.77e-06	2	68	2	32991341
Pubmed	Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport.	FASN SREBF1	3.77e-06	2	68	2	12213084
Pubmed	YAP1-TFE3 gene fusion variant in clear cell stromal tumour of lung: report of two cases in support of a distinct entity.	YAP1 TFE3	3.77e-06	2	68	2	34156713
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	3.77e-06	2	68	2	34156443
Pubmed	Expression status of fatty acid synthase (FAS) but not HER2 is correlated with the differentiation grade and prognosis of esophageal carcinoma.	ERBB2 FASN	3.77e-06	2	68	2	23419663
Pubmed	TIRF high-content assay development for the evaluation of drug efficacy of chemotherapeutic agents against EGFR-/HER2-positive breast cancer cell lines.	ERBB2 TICAM1	3.77e-06	2	68	2	26886741
Pubmed	Metaplastic thymoma: a distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions.	YAP1 MAML2	3.77e-06	2	68	2	31641231
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	3.77e-06	2	68	2	27280393
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	3.77e-06	2	68	2	36869380
Pubmed	SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.	FASN SREBF1	3.77e-06	2	68	2	33665967
Pubmed	RUNX2 promotes malignant progression in gastric cancer by regulating COL1A1.	RUNX2 COL1A1	3.77e-06	2	68	2	33896817
Pubmed	FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration.	ERBB2 FASN	3.77e-06	2	68	2	26936618
Pubmed	Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.	FASN SREBF1	3.77e-06	2	68	2	18281474
Pubmed	Expressions of fatty acid synthase and HER2 are correlated with poor prognosis of ovarian cancer.	ERBB2 FASN	3.77e-06	2	68	2	25433947
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	3.77e-06	2	68	2	25346535
Pubmed	YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis.	YAP1 COL1A1	3.77e-06	2	68	2	33087321
Pubmed	Sterol regulatory element-binding protein-1/fatty acid synthase involvement in proliferation inhibition and apoptosis promotion induced by progesterone in endometrial cancer.	FASN SREBF1	3.77e-06	2	68	2	24105476
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	ZNF384 KMT2D ZFP36L2 YAP1 SIN3A SRCAP SRRM2	4.75e-06	341	68	7	32971831
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SCAF1 KMT2C KMT2D UBN1 YAP1 SREBF1 SIN3A KAT2A TAF4 SRCAP SRRM2 TFE3	7.09e-06	1294	68	12	30804502
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZNF384 KMT2C FASN KMT2D EBF3 SIN3A KAT2A TAF4 RUNX2 SRRM2 DNM2	9.10e-06	1103	68	11	34189442
Pubmed	A microRNA regulatory mechanism of osteoblast differentiation.	RUNX2 COL1A1	1.13e-05	3	68	2	19933329
Pubmed	Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.	ERBB2 FASN	1.13e-05	3	68	2	18211286
Pubmed	Fatty acid synthase, Her2/neu, and E2F1 as prognostic markers of progression in non-muscle invasive bladder cancer.	ERBB2 FASN	1.13e-05	3	68	2	30684846
Pubmed	The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation.	YAP1 RUNX2	1.13e-05	3	68	2	17438369
Pubmed	B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN.	FASN SREBF1	1.13e-05	3	68	2	27939887
Pubmed	YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate.	YAP1 COL1A1	1.13e-05	3	68	2	28513598
Pubmed	Transcriptional integration of mitogenic and mechanical signals by Myc and YAP.	YAP1 COL1A1	1.13e-05	3	68	2	29141911
Pubmed	Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN).	FASN SREBF1	1.13e-05	3	68	2	18682402
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2D	1.13e-05	3	68	2	23932714
Pubmed	Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice.	RUNX2 COL1A1	1.13e-05	3	68	2	10357935
Pubmed	Clinical importance of FASN in relation to HIF-1α and SREBP-1c in gastric adenocarcinoma.	FASN SREBF1	1.13e-05	3	68	2	30914315
Pubmed	Normal hematopoietic stem cell function in mice with enforced expression of the Hippo signaling effector YAP1.	YAP1 COL1A1	1.13e-05	3	68	2	22363786
Pubmed	Genetic variation in genes of the fatty acid synthesis pathway and breast cancer risk.	FASN SREBF1	1.13e-05	3	68	2	19252981
Pubmed	FAS/SREBP-1c contributes to colorectal carcinogenesis through calcium signaling pathway and cAMP signaling pathway.	FASN SREBF1	1.13e-05	3	68	2	38143182
Pubmed	Enigma proteins regulate YAP mechanotransduction.	PDLIM7 YAP1	1.13e-05	3	68	2	30404826
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2C KMT2D	1.13e-05	3	68	2	22183980
Pubmed	HER2 and EGFR gene copy number alterations are predominant in high-grade salivary mucoepidermoid carcinoma irrespective of MAML2 fusion status.	ERBB2 MAML2	1.13e-05	3	68	2	23855785
Pubmed	ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration.	ERBB2 YAP1	1.13e-05	3	68	2	33046882
Pubmed	Salt-inducible Kinases Are Critical Determinants of Female Fertility.	SIK2 SIK3	1.13e-05	3	68	2	32343771
Pubmed	HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.	KMT2C KMT2D	1.13e-05	3	68	2	21683083
Pubmed	Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.	SIK2 SIK3	1.13e-05	3	68	2	27920213
Pubmed	Significance of YAP1-MAML2 rearrangement and GTF2I mutation in the diagnosis and differential diagnosis of metaplastic thymoma.	YAP1 MAML2	1.13e-05	3	68	2	37489594
Pubmed	ShcA promotes chondrocyte hypertrophic commitment and osteoarthritis in mice through RunX2 nuclear translocation and YAP1 inactivation.	YAP1 RUNX2	1.13e-05	3	68	2	35840017
Pubmed	Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.	KAT2A TFE3	1.13e-05	3	68	2	31750630
Pubmed	Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD.	FASN SREBF1	1.13e-05	3	68	2	28027934
Pubmed	Metformin targets Clusterin to control lipogenesis and inhibit the growth of bladder cancer cells through SREBP-1c/FASN axis.	FASN SREBF1	1.13e-05	3	68	2	33649289
Pubmed	A functional interaction between Hippo-YAP signalling and SREBPs mediates hepatic steatosis in diabetic mice.	YAP1 SREBF1	1.13e-05	3	68	2	30821074
Pubmed	Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice.	SIK2 SIK3	1.13e-05	3	68	2	25619259
Pubmed	Combined overexpression of SIRT1 and knockout of GCN5 in adult skeletal muscle does not affect glucose homeostasis or exercise performance in mice.	KAT2A COL1A1	1.13e-05	3	68	2	31794263
Pubmed	Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c.	FASN SREBF1	1.13e-05	3	68	2	12531699
Pubmed	Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma.	YAP1 MAML2	1.13e-05	3	68	2	31145701
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2C FASN KMT2D PDLIM7 YAP1 SIN3A TAF4 SRCAP	1.18e-05	549	68	8	38280479
Pubmed	Human transcription factor protein interaction networks.	KMT2C KMT2D UBN1 YAP1 SIN3A PATL1 KAT2A TAF4 SRCAP SRRM2 MCRIP2 TFE3	1.91e-05	1429	68	12	35140242
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SCAF1 FASN KMT2D UBN1 YAP1 SIN3A PATL1 SRRM2 DNM2	1.95e-05	774	68	9	15302935
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2C KMT2D	2.25e-05	4	68	2	19221051
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2C KMT2D	2.25e-05	4	68	2	34645806
Pubmed	Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice.	RUNX2 COL1A1	2.25e-05	4	68	2	19307728
Pubmed	[Human osteoblasts response to different magnitudes of mechanical stimulation in vitro].	RUNX2 COL1A1	2.25e-05	4	68	2	19595020
Pubmed	ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.	YAP1 COL1A1	2.25e-05	4	68	2	26058078
Pubmed	Corosolic Acid Inhibits Cancer Progress Through Inactivating YAP in Hepatocellular Carcinoma.	YAP1 RUNX2	2.25e-05	4	68	2	32220262
Pubmed	Inhibition of DNA-dependent protein kinase reduced palmitate and oleate-induced lipid accumulation in HepG2 cells.	FASN SREBF1	2.25e-05	4	68	2	23184344
Pubmed	Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells.	ERBB2 FASN	2.25e-05	4	68	2	23725225
Pubmed	γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6.	FASN SREBF1	2.25e-05	4	68	2	23727646
Pubmed	HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN Pathway.	FASN SREBF1	2.25e-05	4	68	2	25855506
Pubmed	Basic fibroblast growth factor autocrine loop controls human osteosarcoma phenotyping and differentiation.	RUNX2 COL1A1	2.25e-05	4	68	2	12393937
Pubmed	TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex.	YAP1 TFE3	2.25e-05	4	68	2	33913810
Pubmed	Deregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis.	ERBB2 YAP1	2.25e-05	4	68	2	27601049
Pubmed	Sp1 coordinately regulates de novo lipogenesis and proliferation in cancer cells.	FASN SREBF1	2.25e-05	4	68	2	19621387
Pubmed	YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers.	YAP1 COL1A1	2.25e-05	4	68	2	26439301
Pubmed	Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.	SIK2 SIK3	2.25e-05	4	68	2	29941929
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C KMT2D	2.25e-05	4	68	2	28398509
Interaction	TOP3B interactions	SCAF1 ZNF384 KMT2C ERBB2 KIAA0930 FASN KMT2D MAN2A2 TBKBP1 UBN1 ZFP36L2 TRAPPC12 PTPRS SREBF1 PALM TNK2 ZFYVE26 PATL1 KAT2A SRCAP MAST2 MCRIP2 TFE3 COL1A1	1.35e-11	1470	66	24	int:TOP3B
Interaction	SFN interactions	KIAA0930 ZFP36L2 YAP1 PPFIBP1 SIK2 SIK3 MAST2 SRRM2 ARHGEF16 TFE3 DMTN SMTNL2 CDC42EP1	3.15e-07	692	66	13	int:SFN
Interaction	YWHAE interactions	KIAA0930 ZFP36L2 PDLIM7 YAP1 PPFIBP1 SIK2 PAWR TAF4 SIK3 MAST2 SRRM2 ARHGEF16 TFE3 DMTN SMTNL2 CDC42EP1	2.08e-06	1256	66	16	int:YWHAE
Interaction	YWHAG interactions	KIAA0930 ZFP36L2 YAP1 PPFIBP1 SIK2 TNK2 PAWR SIK3 MAST2 SRRM2 ARHGEF16 TFE3 DMTN SMTNL2 CDC42EP1	9.34e-06	1248	66	15	int:YWHAG
Interaction	TRAPPC10 interactions	TRAPPC12 PDLIM7 YAP1 KANK4 DMTN	1.27e-05	92	66	5	int:TRAPPC10
Interaction	YWHAB interactions	KIAA0930 ZFP36L2 YAP1 PPFIBP1 SIK2 SIK3 MAST2 SRRM2 ARHGEF16 TFE3 DMTN SMTNL2 CDC42EP1	2.09e-05	1014	66	13	int:YWHAB
Interaction	CREBBP interactions	KMT2D NFE2 YAP1 SREBF1 SIN3A MAML2 KAT2A RUNX2 SRCAP ARID5A	2.35e-05	599	66	10	int:CREBBP
Interaction	TSC1 interactions	FASN TRAPPC12 PTPRS SREBF1 TRIOBP PATL1 KAT2A ARID5A	2.51e-05	366	66	8	int:TSC1
Interaction	ASH2L interactions	KMT2C KMT2D NFE2 YAP1 SIN3A TAF4 SRCAP	2.52e-05	265	66	7	int:ASH2L
Interaction	H3-3A interactions	ZNF384 KMT2C KMT2D UBN1 PAWR SIN3A KAT2A TAF4 ASB2 SRCAP TFE3	2.89e-05	749	66	11	int:H3-3A
Interaction	HNF4A interactions	KMT2C KMT2D UBN1 SREBF1 KAT2A TAF4 SRCAP	3.20e-05	275	66	7	int:HNF4A
Interaction	EP300 interactions	FASN KMT2D UBN1 YAP1 SREBF1 SIK2 TNK2 SIN3A PATL1 MAML2 KAT2A RUNX2 SRCAP SRRM2 DNM2	3.65e-05	1401	66	15	int:EP300
Interaction	TADA2A interactions	FASN PDLIM7 ZFYVE26 SIN3A KAT2A SRRM2	4.64e-05	198	66	6	int:TADA2A
Interaction	YWHAH interactions	KIAA0930 ZFP36L2 YAP1 PPFIBP1 SIK2 SIK3 MAST2 SRRM2 ARHGEF16 TFE3 DMTN SMTNL2 CDC42EP1	4.96e-05	1102	66	13	int:YWHAH
Interaction	YWHAQ interactions	KIAA0930 FASN ZFP36L2 YAP1 PPFIBP1 SIK2 SIK3 MAST2 ARHGEF16 TFE3 DMTN SMTNL2 CDC42EP1	5.76e-05	1118	66	13	int:YWHAQ
Interaction	YWHAZ interactions	ERBB2 KIAA0930 ZFP36L2 YAP1 PPFIBP1 SIK2 TNK2 SIK3 MAST2 ARHGEF16 TFE3 DMTN SMTNL2 CDC42EP1	7.67e-05	1319	66	14	int:YWHAZ
Interaction	NFIX interactions	KMT2C KMT2D KAT2A TAF4 SRCAP COL1A1	9.88e-05	227	66	6	int:NFIX
Interaction	TRAPPC3 interactions	FASN TRAPPC12 PDLIM7 KANK4	1.13e-04	76	66	4	int:TRAPPC3
Interaction	ARNT interactions	ERBB2 FASN YAP1 SIN3A ARID5A DNM2	1.86e-04	255	66	6	int:ARNT
Interaction	TAF3 interactions	FASN YAP1 KAT2A TAF4	1.99e-04	88	66	4	int:TAF3
Interaction	YAP1 interactions	KMT2C FASN KMT2D NFE2 PDLIM7 YAP1 TRIOBP SIN3A TAF4 RUNX2 SRCAP SRRM2	2.01e-04	1095	66	12	int:YAP1
Interaction	PML interactions	FASN UBN1 YAP1 PAWR SIN3A PATL1 TAF4 RUNX2 ARHGEF16 MCRIP2 DNM2	2.05e-04	933	66	11	int:PML
Interaction	SIRT2 interactions	KIAA0930 TRAPPC12 NFE2 YAP1 KAT2A	2.07e-04	165	66	5	int:SIRT2
Interaction	WDR5 interactions	BHLHE41 ZNF384 KMT2C FASN KMT2D NFE2 PDLIM7 YAP1 SIN3A KAT2A TAF4 DNM2	2.12e-04	1101	66	12	int:WDR5
Interaction	FOXI1 interactions	KMT2C FASN KMT2D YAP1	2.36e-04	92	66	4	int:FOXI1
Cytoband	20q13.33	CABLES2 SOX18 TAF4	2.27e-04	79	68	3	20q13.33
Cytoband	16p13.3	UBN1 C16orf96 SRRM2 MCRIP2	4.86e-04	244	68	4	16p13.3
Cytoband	12p12.1	BHLHE41 PPFIBP1	8.55e-04	29	68	2	12p12.1
GeneFamily	Ataxins\|Trinucleotide repeat containing	ZNF384 KMT2D	1.46e-03	25	41	2	775
GeneFamily	Basic helix-loop-helix proteins	BHLHE41 SREBF1 TFE3	1.97e-03	110	41	3	420
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C KMT2D	2.69e-03	34	41	2	487
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	KMT2C YAP1 PPFIBP1 FHOD3 MAML2 SIK3	5.53e-06	171	68	6	M39234
Coexpression	DASU_IL6_SIGNALING_UP	FASN ZFP36L2 SREBF1 DNM2	1.93e-05	61	68	4	M14344
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SCAF1 KMT2D TICAM1 TNK2 SRCAP SRRM2 CDC42EP1	2.75e-05	338	68	7	M17094
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	C2orf66 GJA4 PPFIBP1 PALM SOX18 DMTN	4.20e-07	187	68	6	55aad84b992412e487a32f4970620189a7380ba6
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	C2orf66 GJA4 PPFIBP1 PALM SOX18 DMTN	4.47e-07	189	68	6	f0418851ad4042c4cd87c8729e4f0d43bdf8fccb
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	HOXA3 LPCAT2 SOX18 PAWR RUNX2	6.24e-06	170	68	5	97df5ffb328196c46568975d2d97722bcc753bf5
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2orf66 GJA4 PPFIBP1 SOX18 DMTN	8.93e-06	183	68	5	38a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPFIBP1 PALM C16orf96 RFLNA DMTN	9.17e-06	184	68	5	1a4297b9d3cc4744bea0408fd5ee7b33ba2a1d78
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2orf66 GJA4 PPFIBP1 SOX18 DMTN	9.41e-06	185	68	5	241ea1e178fffef9e7df971de739e794332d5173
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 EBF3 KANK4 PAWR ARID5A	9.66e-06	186	68	5	1e3ab663e4756975db6d802b2c6c054a94a79393
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	GJA4 PDLIM7 PAWR ASB2 ARID5A	1.24e-05	196	68	5	541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCell	(02)_MMP9/10+\|World / shred by cell type by condition	LPCAT2 PDLIM7 KANK4 PAWR COL1A1	1.34e-05	199	68	5	3f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GJA4 TBKBP1 SOX18 PAWR COL1A1	1.34e-05	199	68	5	1295f34a350bf48987e2fad411aaac3630efd3f1
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HOXA3 BHLHE41 KANK4 SMTNL2	3.22e-05	118	68	4	e5202fadb3f9d91e56337ddad1666196ec748d87
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	HOXA3 SIK2 SMTNL2 COL1A1	5.76e-05	137	68	4	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GJA4 EBF3 PAWR ASB2	6.80e-05	143	68	4	9bfb3674c8f011b9cf928b522777b8d54478db8d
ToppCell	3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3\|bone_marrow / Manually curated celltypes from each tissue	HOXA3 SOX18 PAWR RUNX2	7.98e-05	149	68	4	d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	PTPRS PDLIM7 POM121L2 COL1A1	1.03e-04	159	68	4	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 PPFIBP1 PALM SOX18	1.08e-04	161	68	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EBF3 PTPRS IGDCC3 PALM	1.08e-04	161	68	4	bd520c9a1927d5d5355b4421e6b90b58bfb76a42
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 PPFIBP1 PALM SOX18	1.08e-04	161	68	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 PPFIBP1 PALM SOX18	1.08e-04	161	68	4	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	HOXA3 SOX18 PAWR RUNX2	1.27e-04	168	68	4	d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell	Endothelial-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	GJA4 PPFIBP1 PALM SOX18	1.30e-04	169	68	4	95c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-new-cluster\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF384 GJA4 TBKBP1 SOX18	1.39e-04	172	68	4	2fcc6278ead890019a6505fb4fcb518751262dda
ToppCell	facs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0930 PTPRS C16orf96 RUNX2	1.42e-04	173	68	4	ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN2A2 UBN1 LPCAT2 ASB2	1.42e-04	173	68	4	6e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCell	facs-Marrow-T-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0930 PTPRS C16orf96 RUNX2	1.42e-04	173	68	4	19a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN2A2 UBN1 LPCAT2 ASB2	1.42e-04	173	68	4	4c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell	10x3'2.3-week_17-19-Neuro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERBB2 KANK4 FHOD3 RFLNA	1.48e-04	175	68	4	bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell	10x3'2.3-week_17-19-Neuro-stroma-schwann_cells\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERBB2 KANK4 FHOD3 RFLNA	1.48e-04	175	68	4	8b010220cdfb680ec839572f4933adfb85045ea6
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EBF3 PPFIBP1 PALM DMTN	1.48e-04	175	68	4	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EBF3 PPFIBP1 PALM DMTN	1.48e-04	175	68	4	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	10x3'2.3-week_17-19-Neuro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERBB2 KANK4 FHOD3 RFLNA	1.48e-04	175	68	4	0b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SOX18 TNK2 RFLNA	1.52e-04	176	68	4	c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SOX18 TNK2 RFLNA	1.52e-04	176	68	4	d58ef51002ea50b3037636038214bbb7454cb503
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	HOXA3 PTPRS KANK4 SMTNL2	1.55e-04	177	68	4	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 IGDCC3 PALM DMTN	1.55e-04	177	68	4	dfaed388926ce050730492a532824af68bf4feff
ToppCell	RV-11._Adipocyte\|World / Chamber and Cluster_Paper	FASN PTPRS SIK2 KANK4	1.55e-04	177	68	4	f0edf04930692418953e4f00a917257804ec0ffd
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HOXA3 PTPRS KANK4 SMTNL2	1.55e-04	177	68	4	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	FASN PTPRS SIK2 KANK4	1.58e-04	178	68	4	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2orf66 GJA4 PPFIBP1 DMTN	1.62e-04	179	68	4	40c65e8623547aeb80f9cd2366e29072467ce069
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 PTPRS PPFIBP1 PALM	1.62e-04	179	68	4	ec1d7017da325647b629de703135a404bbdc627d
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SOX18 RFLNA CDC42EP1	1.62e-04	179	68	4	ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SOX18 RFLNA CDC42EP1	1.62e-04	179	68	4	d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA4 EBF3 IGDCC3 SOX18	1.65e-04	180	68	4	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LYPD6B LPCAT2 MAML2 COL1A1	1.69e-04	181	68	4	03a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LYPD6B LPCAT2 MAML2 COL1A1	1.69e-04	181	68	4	8fd64404e57c22c204d835fc5626f73554257b19
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PTPRS FRMD7 FHOD3 COL1A1	1.72e-04	182	68	4	ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCell	droplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 KANK4 SOX18 RFLNA	1.72e-04	182	68	4	f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 PPFIBP1 SOX18 DMTN	1.76e-04	183	68	4	764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell	P03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EBF3 PPFIBP1 PALM DMTN	1.76e-04	183	68	4	89727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 PPFIBP1 PALM DMTN	1.76e-04	183	68	4	2d0d3b486498a7903fa9a1f48b189291da49c430
ToppCell	P03-Endothelial-lymphatic_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EBF3 PPFIBP1 PALM DMTN	1.76e-04	183	68	4	113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 TBKBP1 SREBF1 PAWR	1.76e-04	183	68	4	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	UBN1 SIN3A KAT2A COL1A1	1.80e-04	184	68	4	9cbfb9f09476b4d09eb8f92c6f21e449dabcfa98
ToppCell	(6)_Endothelial-F_(Lymphatics)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	PPFIBP1 PALM SOX18 DMTN	1.80e-04	184	68	4	03ea613e00b45c81b752c14505a0538d698f551e
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Memory_B_cells\|bone_marrow / Manually curated celltypes from each tissue	BHLHE41 LYPD6B IGHD PAWR	1.80e-04	184	68	4	ffc9eec123de34a4f17ed27fe4f0a1b3cb84697f
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 KANK4 IGDCC3 SOX18	1.83e-04	185	68	4	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	HOXA3 PTPRS PALM COL1A1	1.83e-04	185	68	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 PALM SOX18 DMTN	1.83e-04	185	68	4	9de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HOXA3 KANK4 SMTNL2 COL1A1	1.83e-04	185	68	4	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 PALM SOX18 DMTN	1.83e-04	185	68	4	18f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HOXA3 ZFP36L2 KANK4 COL1A1	1.83e-04	185	68	4	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HOXA3 ZFP36L2 KANK4 SMTNL2	1.87e-04	186	68	4	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 PPFIBP1 PALM DMTN	1.87e-04	186	68	4	9579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 PPFIBP1 KANK4 SOX18	1.87e-04	186	68	4	4ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF3 KANK4 PAWR ARID5A	1.91e-04	187	68	4	b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCell	tumor_Lung-Endothelial_cells-Lymphatic_ECs\|tumor_Lung / Location, Cell class and cell subclass	PPFIBP1 TRIOBP SOX18 DMTN	1.91e-04	187	68	4	87ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LYPD6B LPCAT2 RFLNA ARHGEF16	1.91e-04	187	68	4	8e8b147258982b359447add5027318f5b6d51963
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HOXA3 KANK4 SMTNL2 COL1A1	1.91e-04	187	68	4	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	droplet-Kidney-nan-3m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 KANK4 IGDCC3 SOX18	1.95e-04	188	68	4	67c04f446fa4528b13a381622e88eb1f314cc6d5
ToppCell	11.5-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	BHLHE41 GJA4 PAWR ARID5A	1.95e-04	188	68	4	916971d8660fd20f616346953874e89d2cd13e88
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BHLHE41 LYPD6B IGHD PAWR	1.95e-04	188	68	4	5707786cc4452dc34f95db2b3cd29f6e025c0622
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 PALM SOX18 DMTN	1.95e-04	188	68	4	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BHLHE41 LYPD6B PAWR KAT2A	1.95e-04	188	68	4	cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCell	droplet-Kidney-nan-3m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 KANK4 IGDCC3 SOX18	1.95e-04	188	68	4	03a7f6538cfddc230c0eab10c3613929addd7e33
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 PALM SOX18 DMTN	1.95e-04	188	68	4	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	droplet-Marrow-BM-1m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FASN KAT2A MCRIP2 NUFIP1	1.99e-04	189	68	4	b81540e097e95158851e07bfd78640ed6e64c2cf
ToppCell	droplet-Marrow-BM-1m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FASN KAT2A MCRIP2 NUFIP1	1.99e-04	189	68	4	0fda1a3f1e87fadf5309c8267beaa4501983b1dd
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	PTPRS FHOD3 RUNX2 COL1A1	1.99e-04	189	68	4	46c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRS PDLIM7 PALM RFLNA	1.99e-04	189	68	4	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PPFIBP1 PALM SOX18 DMTN	1.99e-04	189	68	4	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDLIM7 ASB2 ARID5A COL1A1	2.03e-04	190	68	4	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 PPFIBP1 SOX18 DMTN	2.03e-04	190	68	4	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Lymphatic\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	PPFIBP1 PALM SOX18 DMTN	2.03e-04	190	68	4	8d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	EBF3 PTPRS PALM COL1A1	2.03e-04	190	68	4	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDLIM7 ASB2 ARID5A COL1A1	2.03e-04	190	68	4	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDLIM7 ASB2 ARID5A COL1A1	2.03e-04	190	68	4	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	remission-B_memory\|World / disease stage, cell group and cell class	BHLHE41 LYPD6B PAWR KAT2A	2.03e-04	190	68	4	c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDLIM7 ASB2 ARID5A COL1A1	2.03e-04	190	68	4	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_early\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FASN IGDCC3 PAWR ARHGEF16	2.03e-04	190	68	4	9f5f65869dad9a43ac94f81f9a19c72ffe5adc3c
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GJA4 PPFIBP1 SOX18 DMTN	2.03e-04	190	68	4	103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 PPFIBP1 PALM DMTN	2.03e-04	190	68	4	6b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BHLHE41 LYPD6B PAWR KAT2A	2.07e-04	191	68	4	22134a2c1a92208bc1629a620ce73a56502613c2
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GJA4 PPFIBP1 SOX18 DMTN	2.07e-04	191	68	4	d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCell	severe_COVID-19-B_memory\|World / disease group, cell group and cell class (v2)	BHLHE41 LYPD6B PAWR KAT2A	2.07e-04	191	68	4	3b57e353b74ebc866d0e11deeba31fa764c42325
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BHLHE41 GJA4 PAWR ARID5A	2.11e-04	192	68	4	55f95454399fd533df75db06584eaa48d6ee3830
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SOX18 COL1A1 CDC42EP1	2.11e-04	192	68	4	be75783d9578974b662e1cb13bd3442a921fd50a
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BHLHE41 LYPD6B PAWR KAT2A	2.11e-04	192	68	4	debd471f61cf3606b8e9c246add0be5df601af7f
ToppCell	COVID-19_Mild-Lymphoid_B-B_memory\|COVID-19_Mild / Disease group, lineage and cell class	BHLHE41 LYPD6B PAWR KAT2A	2.11e-04	192	68	4	d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BHLHE41 LYPD6B PAWR KAT2A	2.11e-04	192	68	4	314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SOX18 COL1A1 CDC42EP1	2.11e-04	192	68	4	4fc98f30f8e738816cd93101fbe8ac40889e302a
Drug	Norethindrone [68-22-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A	KIAA0930 MAN2A2 ZFP36L2 TNK2 SRCAP DMTN COL1A1	1.71e-06	195	67	7	5474_UP
Drug	Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A	GJA4 PPFIBP1 SIK2 AGFG2 PALM RUNX2 SRCAP	1.83e-06	197	67	7	7405_UP
Drug	Chlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A	ERBB2 KIAA0930 ZFP36L2 PDLIM7 PALM SRCAP MAST2	1.83e-06	197	67	7	3235_DN
Drug	NSC116069	ERBB2 FASN YAP1 FRMD7 SREBF1	3.61e-06	79	67	5	CID000028517
Drug	Olmesartan Medoxomil	FASN SREBF1 COL1A1	3.95e-06	11	67	3	ctd:D000068557
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZNF384 MAN2A2 ZFP36L2 KAT2A SRRM2 ARHGEF16	1.01e-05	168	67	6	6820_DN
Drug	Puromycin dihydrochloride [58-58-2]; Down 200; 7.4uM; HL60; HT_HG-U133A	KIAA0930 FASN HTRA2 ZFP36L2 NFE2 PRDM13	1.20e-05	173	67	6	2448_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	MAN2A2 YAP1 KAT2A SRCAP SRRM2 ARHGEF16	1.65e-05	183	67	6	3510_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	ZFP36L2 TRAPPC12 TICAM1 SIK2 ZFYVE26 CDC42EP1	1.81e-05	186	67	6	916_DN
Drug	Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A	ZNF384 ERBB2 MAN2A2 PDLIM7 ARHGEF16 DNM2	2.23e-05	193	67	6	7014_DN
Drug	Tetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A	SIK2 AGFG2 PALM ARID5A COL1A1 CDC42EP1	2.23e-05	193	67	6	2748_UP
Drug	Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MAN2A2 TBKBP1 ZFP36L2 SRCAP MAST2 COL1A1	2.36e-05	195	67	6	5386_UP
Drug	F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A	KIAA0930 MAN2A2 AGFG2 SRRM2 ARHGEF16 COL1A1	2.36e-05	195	67	6	6424_DN
Drug	Chlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A	TICAM1 SIK2 TNK2 SRCAP ARID5A COL1A1	2.36e-05	195	67	6	4345_DN
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	PTPRS PDLIM7 TICAM1 SREBF1 SRCAP MAST2	2.36e-05	195	67	6	6163_DN
Drug	Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A	KIAA0930 MAN2A2 TBKBP1 ZFP36L2 TICAM1 PAWR	2.36e-05	195	67	6	3478_UP
Drug	Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; HL60; HT_HG-U133A	GJA4 AGFG2 TNK2 RUNX2 DMTN COL1A1	2.43e-05	196	67	6	2528_UP
Drug	Ioxaglic acid [59017-64-0]; Down 200; 3.2uM; MCF7; HT_HG-U133A	SIK2 TNK2 PAWR MAST2 SRRM2 DMTN	2.43e-05	196	67	6	7470_DN
Drug	Clorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A	KIAA0930 ZFP36L2 TNK2 SRCAP ARID5A CDC42EP1	2.43e-05	196	67	6	2884_UP
Drug	Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	MAN2A2 ZFP36L2 AGFG2 PALM TNK2 CDC42EP1	2.43e-05	196	67	6	5642_UP
Drug	Brinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	PDLIM7 PAWR SRCAP MAST2 DMTN COL1A1	2.43e-05	196	67	6	5016_DN
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	BHLHE41 ZFP36L2 PDLIM7 SREBF1 SRCAP MAST2	2.43e-05	196	67	6	2974_DN
Drug	Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A	ZFP36L2 TICAM1 AGFG2 KAT2A SRCAP COL1A1	2.43e-05	196	67	6	6273_UP
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; PC3; HT_HG-U133A	ERBB2 MAN2A2 HTRA2 TICAM1 SIK2 TNK2	2.50e-05	197	67	6	7130_DN
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	TBKBP1 PPFIBP1 TICAM1 PALM SRCAP DMTN	2.50e-05	197	67	6	3399_DN
Drug	Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; HL60; HG-U133A	TRAPPC12 NFE2 ZFYVE26 SRCAP MAST2 DMTN	2.50e-05	197	67	6	1763_UP
Drug	Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	BHLHE41 MAN2A2 ZFP36L2 PTPRS SRRM2 DMTN	2.50e-05	197	67	6	3247_UP
Drug	N-piperidinyl-(8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrobenzo(6,7)cyclohepta(1,2-c)pyrazole-3-carboxamide)	FASN SREBF1	2.55e-05	3	67	2	ctd:C475771
Drug	neoeriocitrin	RUNX2 COL1A1	2.55e-05	3	67	2	ctd:C553460
Drug	Primidone [125-33-7]; Down 200; 18.4uM; MCF7; HT_HG-U133A	TBKBP1 ZFP36L2 PALM SRCAP MAST2 SRRM2	2.57e-05	198	67	6	3402_DN
Drug	estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A	AGFG2 TRIOBP TNK2 PAWR KAT2A COL1A1	2.57e-05	198	67	6	6200_UP
Drug	Ketoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A	TBKBP1 PTPRS PAWR DMTN COL1A1 CDC42EP1	2.57e-05	198	67	6	2316_DN
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	TBKBP1 UBN1 PTPRS SIK2 SRRM2 COL1A1	2.57e-05	198	67	6	2303_DN
Drug	Metolazone [17560-51-9]; Up 200; 11uM; PC3; HG-U133A	ERBB2 KIAA0930 TRAPPC12 TRIOBP PALM CDC42EP1	2.65e-05	199	67	6	1932_UP
Drug	Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	UBN1 ZFP36L2 TICAM1 AGFG2 KAT2A SRRM2	2.65e-05	199	67	6	3203_DN
Drug	Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ZFP36L2 PDLIM7 POM121L2 SRCAP ARID5A DMTN	2.65e-05	199	67	6	6802_UP
Drug	estradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ZFP36L2 PDLIM7 SIK2 KAT2A SRCAP ARHGEF16	2.72e-05	200	67	6	988_DN
Drug	Scopoletin	FASN TICAM1 SREBF1	6.77e-05	27	67	3	ctd:D012603
Drug	cobaltiprotoporphyrin	FASN TICAM1 SREBF1 RUNX2 COL1A1	1.06e-04	159	67	5	ctd:C007095
Drug	High Fructose Corn Syrup	FASN SREBF1	1.27e-04	6	67	2	ctd:D066248
Drug	atheronal-A	FASN SREBF1	1.27e-04	6	67	2	ctd:C512174
Drug	12 p	BHLHE41 ZNF384 ERBB2 ZFP36L2 YAP1 PPFIBP1	1.55e-04	274	67	6	CID000081248
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	MAN2A2 ZFP36L2 YAP1 SRRM2 ARHGEF16	1.62e-04	174	67	5	6493_DN
Drug	Rifabutin [72559-06-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A	KAT2A SRCAP MAST2 SRRM2 ARHGEF16	1.66e-04	175	67	5	3873_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ZFP36L2 YAP1 SRRM2 ARHGEF16 CDC42EP1	1.66e-04	175	67	5	6891_DN
Drug	(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; HL60; HT_HG-U133A	KIAA0930 FASN PRDM13 KAT2A SRCAP	1.80e-04	178	67	5	2977_DN
Drug	Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; HL60; HG-U133A	MAN2A2 PDLIM7 SIK2 SIK3 DNM2	1.90e-04	180	67	5	1752_UP
Drug	Perphenazine [58-39-9]; Up 200; 10uM; MCF7; HT_HG-U133A	AGFG2 POM121L2 TNK2 SRCAP COL1A1	2.10e-04	184	67	5	1540_UP
Drug	2-propylpentanoic acid; Down 200; 10000uM; HL60; HG-U133A	MAN2A2 ZFP36L2 NFE2 SRCAP SRRM2	2.38e-04	189	67	5	410_DN
Drug	PNU-0230031 [267429-39-0]; Up 200; 10uM; MCF7; HT_HG-U133A	MAN2A2 PDLIM7 SOX18 SRCAP ARID5A	2.44e-04	190	67	5	3629_UP
Drug	Ethisterone [434-03-7]; Down 200; 12.8uM; PC3; HT_HG-U133A	ZFP36L2 POM121L2 SRCAP SRRM2 ARID5A	2.44e-04	190	67	5	4340_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	KIAA0930 PTPRS PDLIM7 TICAM1 PAWR	2.50e-04	191	67	5	5581_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	KIAA0930 ZFP36L2 PDLIM7 TNK2 ZFYVE26	2.50e-04	191	67	5	998_DN
Drug	Disulfiram [97-77-8]; Up 200; 13.4uM; PC3; HT_HG-U133A	TBKBP1 ZFP36L2 TICAM1 SRCAP ARHGEF16	2.50e-04	191	67	5	5729_UP
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A	BHLHE41 ZFP36L2 PDLIM7 SRCAP CDC42EP1	2.56e-04	192	67	5	4395_DN
Drug	17-AAG; Down 200; 1uM; HL60; HT_HG-U133A	BHLHE41 TICAM1 PRDM13 SRCAP ARID5A	2.56e-04	192	67	5	6185_DN
Drug	Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A	GJA4 PAWR KAT2A SRCAP DMTN	2.56e-04	192	67	5	6044_DN
Drug	Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A	ZFP36L2 PDLIM7 AGFG2 COL1A1 CDC42EP1	2.56e-04	192	67	5	4152_DN
Drug	Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A	AGFG2 TRIOBP PALM TNK2 COL1A1	2.62e-04	193	67	5	3708_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	TRIOBP KAT2A SRCAP ARID5A DNM2	2.62e-04	193	67	5	1284_DN
Drug	Clemastine fumarate [14976-57-9]; Up 200; 8.6uM; HL60; HT_HG-U133A	HOXA3 ZFYVE26 SRRM2 ARHGEF16 DMTN	2.62e-04	193	67	5	2412_UP
Drug	Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A	PDLIM7 PPFIBP1 TRIOBP PAWR COL1A1	2.62e-04	193	67	5	3614_DN
Drug	C75; Down 200; 10uM; MCF7; HT_HG-U133A	TICAM1 AGFG2 TNK2 DMTN COL1A1	2.62e-04	193	67	5	6394_DN
Drug	Clotrimazole [23593-75-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A	ZNF384 GJA4 TICAM1 DMTN COL1A1	2.62e-04	193	67	5	6207_UP
Drug	(-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA	HTRA2 ZFP36L2 PTPRS AGFG2 PALM	2.62e-04	193	67	5	982_UP
Drug	5248896; Up 200; 11uM; MCF7; HT_HG-U133A_EA	TBKBP1 ZFP36L2 SRCAP SRRM2 ARHGEF16	2.68e-04	194	67	5	955_UP
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A	ZFP36L2 PDLIM7 SRCAP MAST2 COL1A1	2.68e-04	194	67	5	4335_DN
Drug	Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT_HG-U133A	TBKBP1 ZFP36L2 SREBF1 MAST2 SRRM2	2.68e-04	194	67	5	3526_UP
Drug	Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	ERBB2 TBKBP1 AGFG2 SRCAP COL1A1	2.68e-04	194	67	5	3846_UP
Drug	Zalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A	KIAA0930 POM121L2 SRCAP MAST2 COL1A1	2.68e-04	194	67	5	7352_UP
Drug	0316684-0000 [391209-55-5]; Down 200; 10uM; PC3; HT_HG-U133A	ERBB2 TICAM1 SIK2 SRCAP SRRM2	2.68e-04	194	67	5	7098_DN
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A	HOXA3 POM121L2 TNK2 SRCAP DMTN	2.68e-04	194	67	5	6102_UP
Drug	2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A	ZNF384 UBN1 PDLIM7 SREBF1 TNK2	2.68e-04	194	67	5	1209_DN
Drug	PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A	FASN PTPRS PALM MAST2 ARHGEF16	2.68e-04	194	67	5	4291_DN
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; PC3; HT_HG-U133A	TBKBP1 ZFP36L2 PDLIM7 DMTN CDC42EP1	2.68e-04	194	67	5	4248_DN
Drug	diclofenac sodium; Down 200; 10uM; MCF7; HG-U133A	ZFP36L2 PDLIM7 TNK2 MAST2 DNM2	2.75e-04	195	67	5	333_DN
Drug	Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A	BHLHE41 KIAA0930 MAN2A2 ZFP36L2 COL1A1	2.75e-04	195	67	5	3456_UP
Drug	Ursolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ZFP36L2 PDLIM7 TICAM1 PALM CDC42EP1	2.75e-04	195	67	5	2230_DN
Drug	wortmannin; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA	ZFP36L2 PALM SRCAP DMTN CDC42EP1	2.75e-04	195	67	5	911_DN
Drug	0198306-0000 [212631-61-3]; Down 200; 10uM; MCF7; HT_HG-U133A	KIAA0930 ZFP36L2 PDLIM7 TICAM1 ARHGEF16	2.75e-04	195	67	5	7099_DN
Drug	Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A	PTPRS PAWR SRRM2 ARHGEF16 DMTN	2.75e-04	195	67	5	4742_DN
Drug	Sulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A	MAN2A2 PDLIM7 PPFIBP1 SIK2 MAST2	2.75e-04	195	67	5	3718_DN
Drug	Flecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A	GJA4 KMT2D TICAM1 SRCAP COL1A1	2.75e-04	195	67	5	3843_UP
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	GJA4 MAN2A2 ZFP36L2 SIK2 SRCAP	2.81e-04	196	67	5	5350_UP
Drug	Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	ZFP36L2 PTPRS TNK2 DMTN COL1A1	2.81e-04	196	67	5	2815_UP
Drug	Loxapine succinate [27833-64-3]; Down 200; 9uM; MCF7; HT_HG-U133A	AGFG2 TRIOBP KAT2A MAST2 ARHGEF16	2.81e-04	196	67	5	5293_DN
Drug	Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	BHLHE41 ZFP36L2 PALM SRRM2 DNM2	2.81e-04	196	67	5	3256_UP
Drug	Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A	SRCAP ARHGEF16 DNM2 COL1A1 CDC42EP1	2.81e-04	196	67	5	4540_DN
Drug	Methiazole; Down 200; 15uM; MCF7; HT_HG-U133A	ZFP36L2 TICAM1 AGFG2 SRCAP CDC42EP1	2.81e-04	196	67	5	3878_DN
Drug	PNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A	MAN2A2 AGFG2 PALM POM121L2 COL1A1	2.81e-04	196	67	5	3732_UP
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A	PTPRS SRCAP ARHGEF16 ARID5A DMTN	2.81e-04	196	67	5	1494_UP
Drug	CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A	ZFP36L2 PTPRS TICAM1 TNK2 ARHGEF16	2.81e-04	196	67	5	4560_DN
Drug	Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A	ZNF384 PDLIM7 AGFG2 SIK3 MAST2	2.81e-04	196	67	5	2876_DN
Drug	Amikacin hydrate [37517-28-5]; Down 200; 6.6uM; MCF7; HT_HG-U133A	ZFP36L2 PPFIBP1 SIK2 SRRM2 COL1A1	2.81e-04	196	67	5	3233_DN
Drug	Bacitracin [1405-87-4]; Down 200; 2.8uM; MCF7; HT_HG-U133A	PDLIM7 PPFIBP1 SIK2 SRCAP ARHGEF16	2.81e-04	196	67	5	7448_DN
Drug	Esculin Hydrate [531-75-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TBKBP1 ZFP36L2 PALM SRCAP COL1A1	2.81e-04	196	67	5	3390_DN
Drug	Pheniramine maleate [132-20-7]; Up 200; 11.2uM; PC3; HT_HG-U133A	HOXA3 KMT2D PALM PAWR SRRM2	2.88e-04	197	67	5	4012_UP
Drug	Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A	AGFG2 TRIOBP TNK2 DNM2 COL1A1	2.88e-04	197	67	5	3122_DN
Drug	Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A	BHLHE41 ZFP36L2 PDLIM7 PPFIBP1 TNK2	2.88e-04	197	67	5	4832_DN
Drug	Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A	KIAA0930 PTPRS AGFG2 PAWR COL1A1	2.88e-04	197	67	5	6265_UP
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	5.08e-06	2	67	2	DOID:0080598 (implicated_via_orthology)
Disease	Epithelioid hemangioendothelioma	YAP1 TFE3	5.06e-05	5	67	2	C0206732
Disease	Malignant neoplasm of breast	HOXA3 ERBB2 FASN KMT2D TRAPPC12 PDLIM7 YAP1 TICAM1 ZFYVE26 SIK3	1.48e-04	1074	67	10	C0006142
Disease	oral squamous cell carcinoma (is_marker_for)	BHLHE41 ERBB2 KMT2D	4.03e-04	63	67	3	DOID:0050866 (is_marker_for)
Disease	response to radiation, Urinary retention	PTPRS DNM2	6.76e-04	17	67	2	GO_0009314, HP_0000016
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	MAML2 RFLNA	1.04e-03	21	67	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	Squamous cell carcinoma of esophagus	KMT2C FASN KMT2D	1.33e-03	95	67	3	C0279626
Disease	Intrahepatic Cholangiocarcinoma	KMT2C ERBB2	1.36e-03	24	67	2	C0345905
Disease	stomach carcinoma (is_marker_for)	KMT2C ERBB2	1.36e-03	24	67	2	DOID:5517 (is_marker_for)
Disease	Extrahepatic Cholangiocarcinoma	KMT2C ERBB2	1.36e-03	24	67	2	C3805278
Disease	eosinophil percentage of leukocytes	NFE2 SIK2 C16orf96 SIK3 RUNX2 ASB2 ARID5A	1.50e-03	746	67	7	EFO_0007991
Disease	Cholangiocarcinoma	KMT2C ERBB2	1.59e-03	26	67	2	C0206698
Disease	Sezary Syndrome	KMT2C KMT2D	1.72e-03	27	67	2	C0036920
Disease	Ovarian Mucinous Adenocarcinoma	TNK2 MAST2	2.26e-03	31	67	2	C1335167

Protein segments in the cluster

Peptide	Gene	Start	Entry
QPHPPPAFSPAFDNL	ERBB2	1206	P04626
ADPAPLPSQEPPRNS	ARID5A	201	Q03989
PFPQPAAAAAPFCLP	BHLHE41	336	Q9C0J9
PPAPQPSSRFNDAPA	ASB2	516	Q96Q27
DDAAFQPQVPAPPQP	ARHGEF16	46	Q5VV41
NNSNPGARPPPPRAT	TNK2	926	Q07912
NAAAPSPVRAPAPSP	PALM	111	O75781
EPPAASASAAPPPQR	PAWR	111	Q96IZ0
APAAQPRPLQSPAPA	KAT2A	11	Q92830
RAFFSAPPSATPPPQ	PATL1	316	Q86TB9
QRPFAQPAPAAPASP	FOXI3	106	A8MTJ6
PSFTPALPAAPPVAN	KMT2C	3551	Q8NEZ4
FPPASAAGQPDPRPT	IGDCC3	721	Q8IVU1
PPSSASPPQNASNNP	HOXA3	121	O43365
DSQRNSPFQIPPPSP	PPFIBP1	566	Q86W92
PVFNTEPNPNPDPRD	FRMD7	421	Q6ZUT3
PPTPERNNRPAFFSP	KIAA0930	291	Q6ICG6
NSDLFPAPPQIPSRP	DNM2	821	P50570
ARPFGAPPPADSAPQ	PDLIM7	116	Q9NR12
PFSDPFQLDNPDPQP	PTPRS	1261	Q13332
RQASFFPPPVPNPFV	LPCAT2	31	Q7L5N7
SQAAATAAPPPPPDY	MAML2	116	Q8IZL2
NLTPFPRNPSPFPAS	DERPC	61	P0CG12
PSPPPASPRSQYNFI	HTRA2	136	O43464
TQPQPSRAPPPATEF	C16orf96	416	A6NNT2
PFNSTNFPEPSRPPL	FHOD3	16	Q2V2M9
NTSGFAPARPPPQPR	IGHD	316	P01880
NPPAPAANPSAPAAT	CDC42EP1	251	Q00587
TSQPPRAQPFAQPPG	MCRIP2	41	Q9BUT9
PPEPRPSFFSISPQD	MAN2A2	101	P49641
PLDSPRNFSPNAPAH	MAST2	201	Q6P0Q8
PDSGARPPAAPPLQN	KANK4	76	Q5T7N3
TFPNPFPTNENPRPL	C2orf66	76	Q6UXQ4
ASSRPPLFLDPPPQN	GJA4	301	P35212
SAFAPVVRPQASPPP	EBF3	561	Q9H4W6
NPNALFPPVEFPAPR	FASN	811	P49327
SKFPAAQPPDPNQPA	DMTN	171	Q08495
SPKPPAPDFAAPSQA	PRDM13	191	Q9H4Q3
PPAAPTSAARAPPQA	CABLES2	21	Q9BTV7
NAPSEPSFEPQAPAP	NFE2	41	Q16621
PRPSLNSAPSPFNPQ	RUNX2	266	Q13950
PTAAPAVPPPAAAQN	TAF4	291	O00268
PPAQDQPRSPVPSAF	SRRM2	2441	Q9UQ35
SAQSAPAPAQPAPQP	SIN3A	231	Q96ST3
PPRQPGAAPAPLQFS	SIK2	831	Q9H0K1
DQFPTFPPSAHQQPP	SIK3	926	Q9Y2K2
PASALASPFPSAPNP	SRCAP	1551	Q6ZRS2
ASPFPSAPNPAPAQA	SRCAP	1556	Q6ZRS2
RPPFPLSQGANPQPA	POM121L2	761	Q96KW2
APSFSSPPRQAPEPS	TRIOBP	1171	Q9H2D6
PQSFPAPAPPQFSST	SREBF1	146	P36956
PAAQSPLPSTNPFQP	AGFG2	371	O95081
PPSAGFDFSFLPQPP	COL1A1	1191	P02452
SNPNPPPQCSFDLTP	ZNF384	536	Q8TF68
PPFDAQSPLDSQPQP	NUFIP1	91	Q9UHK0
QAAAAPFPSPAPASP	TFE3	136	P19532
RGPQAAAPPASPEPF	TRAPPC12	266	Q8WVT3
QRSPSPAPAPAPAAA	SCAF1	496	Q9H7N4
PQPAAFPQSLPFPQS	TICAM1	646	Q8IUC6
EARAPPSQLPNPPAS	RFLNA	66	Q6ZTI6
PAPAATQAAPQAPPA	YAP1	36	P46937
IAQNFSAPDPPRPRP	SMTNL2	171	Q2TAL5
RNFAKPSPSAPPPAS	UBN1	716	Q9NPG3
QPPPEPFPAASGSAR	SOX18	181	P35713
AAAPPSPPFSFQLPR	ZFP36L2	421	P47974
QDAAFSNLSPPPAPA	TBKBP1	176	A7MCY6
RSFPPTQPSQEFVPP	ZFYVE26	1786	Q68DK2
DPSQPRPNPPTFAQG	KMT2D	3486	O14686
NVRPPLDPTPFPNSF	LYPD6B	46	Q8NI32