Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF711 ZNF675 ZNF429 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 USF3 ZNF362 ZNF658B ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZNF840P ZNF707	1.47e-11	1459	46	20	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF711 ZNF675 ZNF429 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 USF3 ZNF658B ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZNF840P ZNF707	8.06e-11	1412	46	19	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF711 ZNF675 ZNF429 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF658B ZNF658 ZNF454 ZNF273 ZNF354B ZNF840P ZNF707	8.96e-10	1244	46	17	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF711 ZNF675 ZNF429 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF658B ZNF658 ZNF454 ZNF273 ZNF354B ZNF840P ZNF707	1.24e-09	1271	46	17	GO:0000987
Domain	ZINC_FINGER_C2H2_2	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF474 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	3.91e-17	775	42	20	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF474 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	4.11e-17	777	42	20	PS00028
Domain	-	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	7.13e-17	679	42	19	3.30.160.60
Domain	Znf_C2H2	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF474 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	8.15e-17	805	42	20	IPR007087
Domain	Znf_C2H2/integrase_DNA-bd	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	1.07e-16	694	42	19	IPR013087
Domain	Znf_C2H2-like	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	1.32e-15	796	42	19	IPR015880
Domain	ZnF_C2H2	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	1.73e-15	808	42	19	SM00355
Domain	zf-C2H2	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZNF81 ZNF362 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	2.20e-15	693	42	18	PF00096
Domain	KRAB	ZNF675 ZNF429 ZNF34 ZNF677 ZNF81 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZNF707	1.35e-11	358	42	12	PS50805
Domain	KRAB	ZNF675 ZNF429 ZNF34 ZNF677 ZNF81 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZNF707	1.35e-11	358	42	12	PF01352
Domain	KRAB	ZNF675 ZNF429 ZNF34 ZNF677 ZNF81 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZNF707	1.92e-11	369	42	12	SM00349
Domain	KRAB	ZNF675 ZNF429 ZNF34 ZNF677 ZNF81 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZNF707	1.98e-11	370	42	12	IPR001909
Domain	zf-C2H2_6	ZNF675 ZNF429 ZNF200 ZNF677 ZNF16 ZBTB41 ZNF658 ZNF25 ZNF273 ZNF354B ZFP64	6.86e-11	314	42	11	PF13912
Domain	DUF4599	SPATA31A3 SPATA31A5 SPATA31A7	2.29e-06	12	42	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A5 SPATA31A7	2.29e-06	12	42	3	IPR027970
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF711 ZNF675 EXO1 ZNF429 ZNF200 ZNF34 ZNF677 ICE1 GRIN2A ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZNF707	1.39e-09	1387	29	16	M734
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A1 SPATA31A3 SPATA31A5 SPATA31A7	4.78e-11	6	48	4	25930072
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A1 SPATA31A3 SPATA31A5 SPATA31A7	4.78e-11	6	48	4	20850414
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A1 SPATA31A3 SPATA31A5 SPATA31A7	3.32e-08	24	48	4	32212159
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF34 ZNF25 ZNF273 ZNF354B ZNF707	5.16e-06	181	48	5	37372979
Pubmed	Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.	ZNF429 ZNF273	3.85e-04	21	48	2	7865130
Pubmed	Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity.	FAM184A CCDC168	4.63e-04	23	48	2	22792062
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF16 ZNF25	8.45e-04	31	48	2	2288909
Cytoband	9p13.1	SPATA31A1 SPATA31A3 ZNF658	2.14e-06	24	48	3	9p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A5 SPATA31A7	2.99e-05	8	48	2	chr9q12
Cytoband	Ensembl 112 genes in cytogenetic band chr9p12	SPATA31A1 ZNF658B	1.62e-04	18	48	2	chr9p12
Cytoband	9p12	ZNF658B SPATA31A5	4.27e-04	29	48	2	9p12
Cytoband	5q35.3	ZNF454 ZNF354B	4.49e-03	95	48	2	5q35.3
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	ZNF34 ZNF16 ZNF707	6.13e-03	355	48	3	chr8q24
Cytoband	8q24.3	ZNF34 ZNF707	6.29e-03	113	48	2	8q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF675 ZNF429	7.29e-03	122	48	2	chr19p12
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF711 ZNF675 ZNF429 ZNF200 ZNF34 ZNF677 ZNF16 ZBTB41 ZFP42 ZNF81 ZNF362 ZNF474 ZNF658 ZNF25 ZNF454 ZNF273 ZNF354B ZNF875 ZFP64 ZNF707	4.13e-21	718	31	20	28
GeneFamily	X-linked mental retardation\|Angiotensin receptors	ZNF711 ZNF81	3.71e-03	53	31	2	103
Computational	Genes in the cancer module 67.	EXO1 CCDC88C ZNF273 PDZD2	2.20e-04	227	15	4	MODULE_67
Disease	Mental Retardation, X-Linked Nonsyndromic	ZNF711 ZNF81	1.60e-04	13	43	2	C3501611
Disease	disease free survival	ICE1 CCDC168	3.13e-04	18	43	2	EFO_0000409
Disease	Hypermetropia	CCDC88C ALMS1 SPATA19	4.61e-04	103	43	3	HP_0000540
Disease	Mental Retardation, X-Linked	ZNF711 ZNF81	8.21e-04	29	43	2	C1136249
Disease	white matter hyperintensity measurement	CCDC88C ZNF16 GRIN2A ZNF474	9.69e-04	302	43	4	EFO_0005665
Disease	Mental Retardation, X-Linked 1	ZNF711 ZNF81	1.00e-03	32	43	2	C2931498
Disease	Parkinson disease, disease progression measurement	FAM184A ZNF474	1.49e-03	39	43	2	EFO_0008336, MONDO_0005180
Disease	hypertension, white matter hyperintensity measurement	CCDC88C ZNF474	3.71e-03	62	43	2	EFO_0000537, EFO_0005665
Disease	magnesium measurement	CCDC168 ZNF362	4.19e-03	66	43	2	EFO_0004845

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSEDQSQNKHSRHKK	PRPF4B	31	Q13523
QQSSKHTALHLTKNK	AGBL3	966	Q8NEM8
VLDTKARHQQKHNKA	ADAM23	131	O75077
EKNNQHKPKSHISNI	ALMS1	2996	Q8TCU4
MDTQKQIHKTHNSKN	LINC01587	1	Q99440
NHHNSSKKEKNKTEN	FLG	176	P20930
NHLQQKHSAELQSLK	FAM184A	771	Q8NB25
HAHTKELKTSLNNAQ	CCDC88C	1276	Q9P219
NKHNQGTHLRSKTEK	PDZD2	1806	O15018
NSKEKCSLKHQTRNQ	FAM214A	571	Q32MH5
MHKNSKRNNNLRVSH	FBXO48	1	Q5FWF7
RAKSEHEQKTSHQLQ	ICE1	806	Q9Y2F5
QTQKNHPNHALKESK	GJB6	226	O95452
NTKSHDQSENENKKH	DENND2C	86	Q68D51
KLKDNQSHKEHLTQN	HGSNAT	626	Q68CP4
SNLHDSSHKQRKKVI	CYP26A1	126	O43174
SNIKSHLAKNQGKSH	CCDC168	6921	Q8NDH2
MAKSKNHTTHNQSRK	RPL29	1	P47914
ARHASKVNQHKQKFQ	SPATA31A7	1226	Q8IWB4
LTALEKKQHSQHAKQ	SECISBP2	456	Q96T21
ASIQKRKHHNAENKP	EXO1	771	Q9UQ84
KHHLSKSDLLANQSQ	SPATA19	91	Q7Z5L4
ARHASKVNQHKQKFQ	SPATA31A3	1226	Q5VYP0
ASNLQRHQKNHTREK	ZNF707	216	Q96C28
VLHKFSNSNIHKKRQ	ZNF273	186	Q14593
ARHASKVNQHKQKFQ	SPATA31A1	1226	Q5TZJ5
ARHASKVNQHKQKFQ	SPATA31A5	1226	Q5VU36
KSNLTVHRKKHSNET	ZBTB41	401	Q5SVQ8
SFKSISNLNKHQKTH	ZNF840P	341	A6NDX5
RFNNNSNLNKHKKIH	ZNF840P	481	A6NDX5
LSRHQRTHNKKENSS	ZNF840P	516	A6NDX5
KSVSNLNKHQKTHAG	ZNF840P	531	A6NDX5
NNNSNLSKHKKIHTG	ZNF840P	671	A6NDX5
QLDSRKHNSHDKENK	PREX2	961	Q70Z35
TKKQHRKKNRETHNA	USF3	11	Q68DE3
GKSFNHKTNLNKHER	ZNF200	286	P98182
NQSANLTKHKKIHTG	ZNF675	546	Q8TD23
NLKAHILTHANTNKN	ZFP42	291	Q96MM3
KNLTHRKDQQHNKSS	ZNF677	126	Q86XU0
QNSNLSKHLRIHTKE	ZNF658	451	Q5TYW1
LTAHQKTHTKKRNAE	ZNF25	441	P17030
KQSSNLNSHKKIHSG	ZNF429	491	Q86V71
SNLQSHQRQHNKDKP	ZNF362	326	Q5T0B9
AFSQNSSLKKHQKSH	ZNF16	301	P17020
STLNKHQKIHNEKNA	ZNF454	191	Q8N9F8
HQKIHNEKNANQKIH	ZNF454	196	Q8N9F8
KKRISNKLQQTFHHS	ZNF474	6	Q6S9Z5
KSNLNKHQRSHTGEK	ZNF875	481	P10072
KAFIHNSSLRKHQKN	ZNF354B	221	Q96LW1
NSSLRKHQKNHTGEK	ZNF354B	226	Q96LW1
SNLKTHIKSKHGNNL	ZNF711	546	Q9Y462
RCHKKQHSDQSENKN	ZFP64	596	Q9NTW7
HIHNKSNAAKNLDKT	ZNF81	206	P51508
NNHKRVHRSKKTNTV	ZNF34	211	Q8IZ26
QNSNLSKHLRIHTKE	ZNF658B	211	Q4V348
HREPDNSKNHKTKDN	GRIN2A	1071	Q12879