Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessimport into nucleus

BACH2 BAG3 TSC2 NUP214 CBLB CRY2 PIK3R1 KCNQ2

1.41e-052011128GO:0051170
DomainCaskin_C

CASKIN2 CASKIN1

3.63e-0521132IPR032117
DomainCaskin-tail

CASKIN2 CASKIN1

3.63e-0521132PF16632
DomainSH3

TSPOAP1 NCF2 ASAP1 CASKIN2 PIK3R1 CASKIN1 TJP2 EPS8L3

5.08e-052161138SM00326
DomainSH3

TSPOAP1 NCF2 ASAP1 CASKIN2 PIK3R1 CASKIN1 TJP2 EPS8L3

5.08e-052161138PS50002
DomainSH3_domain

TSPOAP1 NCF2 ASAP1 CASKIN2 PIK3R1 CASKIN1 TJP2 EPS8L3

5.78e-052201138IPR001452
DomainSH3_2

TSPOAP1 CASKIN2 PIK3R1 CASKIN1 TJP2

1.75e-04861135PF07653
DomainSH3_2

TSPOAP1 CASKIN2 PIK3R1 CASKIN1 TJP2

1.75e-04861135IPR011511
DomainPH_dom-like

ROCK2 RAPH1 DAB2 NIBAN2 ASAP1 ARAP3 DGKK OSBPL5 MTMR3 EPS8L3

2.63e-0442611310IPR011993
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2B KIF26A SPEG INPPL1 IRAK1 RAPGEF1 CUL9 TSC2 NUP214 FBXL19 KDM6B MBD6 CIC C6orf132 MICALL1 NCOR2 ORAI1 URB1 TNRC18 ARAP3 BRD2 ADAMTS7 CASKIN1 OSBPL5 MTMR3 KCNQ2 MLLT6 MICAL3 LTK SIPA1L2 CEP170B

6.11e-2011051193135748872
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ROCK2 IRF2BP2 ATXN2L MYBBP1A SMARCA5 KMT2B ATN1 RAPH1 CHAF1A BAG3 CAMSAP3 DAB2 NUP214 NIBAN2 CHAMP1 ZYX CIC MICALL1 NCOR2 BRD2 USP42 ANAPC1 ZC3H4 TJP2 MICAL3 CCDC86 CNOT3

9.19e-207741192715302935
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TSHZ3 ATN1 TSPOAP1 INPPL1 APC2 DAB2 NUP214 CIC ASAP1 C6orf132 NCOR2 ZNF469 TNRC18 PIK3R1 MLLT6 BSN FOXI1

1.39e-134301191735044719
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYBBP1A RAPH1 BAG3 CAMSAP3 NIBAN2 PPM1J ZYX PABIR2 CIC ASAP1 NCOR2 BRD2 PTPRN CASKIN2 PIK3R1 CSPG5 NUP210 MTMR3 PPP1R37 MICAL3 CCDC86

6.77e-1110491192127880917
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ATXN2L RAPH1 INPPL1 RTN4 BAG3 IRAK1 NUP214 NIBAN2 ZYX ASAP1 C6orf132 MICALL1 CASKIN2 PPP1R37 TJP2 CRYBG1

1.10e-105651191625468996
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

ROCK2 ATXN2L MYBBP1A SMARCA5 CHAF1A BAG3 CAMSAP3 DAB2 TACC2 NIBAN2 CHAMP1 ZYX PABIR2 ZC3H4 TJP2

2.15e-105031191516964243
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF26A RTN4 FBF1 NACA KDM6B CHAMP1 MICALL1 MESD CASKIN2 ZC3H4 CASKIN1 OSBPL5 RNF10 BSN PLXNB1

4.30e-105291191514621295
Pubmed

Human transcription factor protein interaction networks.

IRF2BP2 TSHZ3 MYBBP1A SMARCA5 KMT2B ATN1 ATXN7L1 NACA IRAK1 CUL9 NUP214 MBD6 DCAF5 CIC NCOR2 BRD2 DGKK MLLT6 CCDC86 CNOT3 SLX4 FOXI1 SP7

5.42e-1014291192335140242
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SMARCA5 ATN1 ATXN7L1 CHAF1A BACH2 FBF1 IRAK1 CUL9 CHAMP1 DCAF5 CCNT1 NCOR2 ZNF469 BRD2 ANAPC1 ZC3H4 PIK3R1 LTK SIPA1L2 CEP170B

1.37e-0911161192031753913
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

IRF2BP2 ATXN2L MYBBP1A SMARCA5 RAPH1 RTN4 NACA BAG3 IRAK1 TACC2 NUP214 NIBAN2 CHAMP1 ZYX CIC CCNT1 ZC3H4 SIPA1L2

3.25e-099341191833916271
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

IRF2BP2 RAPH1 INPPL1 DAB2 CBLB ASAP1 MICALL1 CASKIN2

3.92e-09108119819531213
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ATXN2L RAPH1 INPPL1 BAG3 CAMSAP3 TSC2 ZYX PABIR2 CIC C6orf132 MICALL1 MLXIPL CASKIN2 RNF10 TJP2 SIPA1L2 CEP170B

6.50e-098611191736931259
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ATXN2L TSPOAP1 RTN4 NACA CAMSAP3 TACC2 SHROOM2 ASAP1 MESD TNRC18 CASKIN1 RNF10 KNDC1 TJP2 KCNQ2 BSN SIPA1L2 CNOT3 CEP170B

1.18e-0811391191936417873
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WDR7 TSPOAP1 SPEG CUL9 NUP214 DCAF5 ASAP1 MTMR3 MICAL3 SIPA1L2 TET3 CEP170B

1.73e-084071191212693553
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

KMT2B CHAF1A RTN4 DAB2 RAPGEF1 CUL9 SHROOM2 ASAP1 URB1 PIK3R1 OSBPL5

1.95e-083291191117474147
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ATXN2L WDR7 RTN4 HCN3 CAMSAP3 CASKIN1 KCNQ2 MICAL3 BSN SIPA1L2 CEP170B

3.36e-083471191117114649
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FBF1 CHAMP1 DCAF5 ZNF469 TNRC18 BRSK1 SLX4

9.03e-08107119711347906
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ATXN2L INPPL1 BACH2 CUL9 TACC2 CIC NCOR2 ANAPC1 BSN SIPA1L2 CNOT3 SLX4 CEP170B

1.23e-075881191338580884
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TSHZ3 KMT2B RAPH1 BAG3 CAMSAP3 IRAK1 NUP214 CHAMP1 CIC NCOR2 ANAPC1

2.19e-074181191134709266
Pubmed

A human MAP kinase interactome.

KIF26A CHAF1A BAG3 DAB2 RAPGEF1 NUP214 CBLB ZYX CIC ASAP1 PIK3R1

9.63e-074861191120936779
Pubmed

CIN85 interacting proteins in B cells-specific role for SHIP-1.

INPPL1 CBLB ASAP1 MICALL1 PIK3R1

1.19e-0654119521725061
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ATXN2L KMT2B ATN1 DAB2 MBD6 ZYX CIC FBLN2 PTPRN MLLT6 DKK3 PDZD4

1.27e-066081191216713569
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ROCK2 ATXN2L MYBBP1A WDR7 RTN4 CAMSAP3 SHROOM2 ASAP1 MLXIPL CASKIN1 KNDC1 TJP2 KCNQ2 MICAL3 BRSK1 BSN SIPA1L2 CEP170B

1.84e-0614311191837142655
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

RAPH1 INPPL1 DAB2 IRAK1 ZYX PABIR2 CRY2 MLXIPL ARAP3 RNF10 KNDC1 TJP2 CRYBG1 SNAPC2 CNOT3

2.76e-0610381191526673895
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ATXN2L MYBBP1A SMARCA5 KMT2B RAPH1 BAG3 IRAK1 CHAMP1 ZYX ANAPC1 TJP2

3.12e-065491191138280479
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

SMARCA5 RAPH1 INPPL1 NACA BAG3 CAMSAP3 NUP214 ZYX ASAP1 CCNT1 ARAP3 PIK3R1 TJP2 CCDC86

3.20e-069161191432203420
Pubmed

Interaction network of human early embryonic transcription factors.

TSHZ3 SMARCA5 KMT2B ATN1 NUP214 MBD6 NCOR2 TNRC18 SLX4

3.58e-06351119938297188
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

KMT2B FBXL19 TET3

4.61e-0610119329276034
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ATXN2L MYBBP1A SMARCA5 CHAF1A NUP214 CHAMP1 CIC CCNT1 NCOR2 BRD2 ZC3H4 MLLT6 CCDC86 SLX4

5.10e-069541191436373674
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ROCK2 MYBBP1A WDR7 HCN3 APC2 CAMSAP3 TSC2 NCOR2 ANAPC1 ZC3H4 CASKIN1 BRSK1 BSN CEP170B

5.67e-069631191428671696
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TSHZ3 BAG3 CUL9 NUP214 CCNT1 TNRC18 ANAPC1 CNOT3

6.10e-06282119823667531
Pubmed

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.

IRF2BP2 ATXN2L MYBBP1A RTN4 NUP214 NIBAN2 NUP210 MICAL3 CCDC86

1.08e-05403119935253629
Pubmed

MLL4 binds TET3.

KMT2B TET3

1.16e-052119238579707
Pubmed

TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment.

KDM6B TET3

1.16e-052119232405722
Pubmed

RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening.

RAD52 SLX4

1.16e-052119230692206
Pubmed

A systematic study of gene mutations in urothelial carcinoma; inactivating mutations in TSC2 and PIK3R1.

TSC2 PIK3R1

1.16e-052119221533174
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

ATXN2L MYBBP1A BAG3 CAMSAP3 NUP214 ZYX DCAF5 ASAP1 NCOR2 TNRC18 ZC3H4

1.63e-056551191135819319
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

MYBBP1A KIF26A SHROOM2 OSBPL5 LTK BSN TET3

1.64e-05233119737704626
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

TSHZ3 BACH2 RTN4 RAPGEF1 TACC2 NIBAN2 CHAMP1 PABIR2 NCOR2 TNRC18 BRD2 ZC3H4 MICAL3 SIPA1L2 CEP170B

1.79e-0512151191515146197
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

NACA IRAK1 NUP214 CIC CCNT1 ANAPC1 SIPA1L2

2.09e-05242119734011540
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

ATXN2L MYBBP1A ARFGEF1 TSC2 CHAMP1 CCNT1 ZC3H4 NUP210

2.40e-05341119832971831
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ROCK2 ATXN2L MYBBP1A SMARCA5 ATN1 INPPL1 RTN4 BAG3 NUP214 CCNT1 NCOR2 TNRC18 PIK3R1 MLLT6 CNOT3

2.42e-0512471191527684187
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

ROCK2 RAPH1 RTN4 BAG3 DAB2 NUP214 NIBAN2 ZYX TMEM245 FMNL1

2.70e-055681191037774976
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ROCK2 TSPOAP1 CUL9 CRY2 CNOT3

2.75e-0510211959734811
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TSHZ3 HCN3 CAMSAP3 OSBPL5 PDZD4

2.89e-05103119510819331
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

BACH2 RTN4 TACC2 POU6F1 CHAMP1 ZYX CIC BRD2 RNF10 ZNF580 SP7

3.36e-057091191122988430
Pubmed

Cbl-b and c-Cbl negatively regulate osteoblast differentiation by enhancing ubiquitination and degradation of Osterix.

CBLB SP7

3.47e-053119225744063
Pubmed

Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix.

KDM6B SP7

3.47e-053119224106268
Pubmed

Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.

CASKIN2 CASKIN1

3.47e-053119231727973
Pubmed

The chromatin-remodeling enzyme ACF is an ATP-dependent DNA length sensor that regulates nucleosome spacing.

SMARCA5 CHAF1A

3.47e-053119217099699
Pubmed

Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression.

BACH2 NCOR2

3.47e-053119217383980
Pubmed

LncRNA ATP1A1-AS1 inhibits cell proliferation and promotes cell apoptosis in thyroid carcinoma by regulating the miR-620/IRF2BP2 axis.

IRF2BP2 ATP1A1-AS1

3.47e-053119236002076
Pubmed

Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry.

RTN4 ORAI1

3.47e-053119224558039
Pubmed

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

CBLB PIK3R1

3.47e-053119211087752
Pubmed

CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein.

CASKIN2 CASKIN1

3.47e-053119212040031
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

ATXN2L MYBBP1A SMARCA5 KMT2B NIBAN2 CBLB CCNT1 URB1 ZC3H4 NUP210 TJP2 CCDC86

3.53e-058471191235850772
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MYBBP1A SMARCA5 KMT2B CHAF1A NUP214 CHAMP1 CIC NCOR2 MLXIPL URB1 BRD2 USP42 ANAPC1 CCDC86 TET3

3.70e-0512941191530804502
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

IRF2BP2 ATN1 CHAMP1 CIC CCNT1 TNRC18 ZC3H4

4.01e-05268119733640491
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

MYBBP1A NACA TACC2 NUP214 NIBAN2 CHAMP1 CRY2 URB1 ANAPC1 ZC3H4 MICAL3 CNOT3 SLX4 CEP170B

4.24e-0511551191420360068
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

KMT2B ARFGEF1 CCNT1 USP42 ZC3H4 SRRM3

4.54e-05186119633637726
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

TSHZ3 SMARCA5 KMT2B CHAF1A CHAMP1 CIC CCNT1 BRD2 MLLT6 CCDC86

4.78e-056081191036089195
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

MYBBP1A SMARCA5 CHAF1A POU6F1 FBXL19 CIC NCOR2 INSM2 ZNF580 CNOT3 UTF1 SP7

4.93e-058771191220211142
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

KMT2B ANAPC1 TJP2 CNOT3

5.13e-0559119428813667
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

IRF2BP2 SMARCA5 SPEG RTN4 CAMSAP3 NUP214 ZC3H4 TJP2 MICAL3

5.57e-05497119936774506
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ROCK2 ATXN2L MYBBP1A SMARCA5 RTN4 NACA BAG3 ARFGEF1 NUP214 NIBAN2 CHAMP1 ZYX ASAP1 NCOR2 TJP2

6.87e-0513671191532687490
Pubmed

Tuberous sclerosis complex proteins control axon formation.

TSC2 BRSK1

6.93e-054119218794346
Pubmed

A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex.

RAPH1 INPPL1

6.93e-054119222915108
Pubmed

Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β.

PTPRN INSM2

6.93e-054119222785238
Pubmed

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi.

TSC2 CCNT1

6.93e-054119226350902
Pubmed

Negative regulation of T cell antigen receptor-mediated Crk-L-C3G signaling and cell adhesion by Cbl-b.

RAPGEF1 CBLB

6.93e-054119212697763
Pubmed

Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin.

RAPH1 INPPL1

6.93e-054119222194892
Pubmed

Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.

ZYX TJP2

6.93e-054119222665060
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYBBP1A ARAP3 ANAPC1 ZC3H4 NUP210 CRYBG1

7.17e-05202119633005030
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ATXN2L MYBBP1A SMARCA5 CUL9 NUP214 URB1 ANAPC1 NUP210 TJP2 CCDC86

8.64e-056531191022586326
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYBBP1A TACC2 SHROOM2 DCAF5 ASAP1 ORAI1 MESD URB1 PIK3R1 TJP2 CRYBG1 SLX4 PLXNB1

9.01e-0510841191311544199
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ROCK2 INPPL1 NIBAN2 CBLB PIK3R1 PPP1R37 MICAL3 SIPA1L2

1.05e-04421119836976175
Pubmed

Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

CBLB PIK3R1

1.15e-045119211526404
Pubmed

PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase.

INPPL1 PIK3R1

1.15e-045119219501627
Pubmed

The CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cells.

CBLB PIK3R1

1.15e-04511929614102
Pubmed

MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.

MICALL1 MICAL3

1.15e-045119212110185
Pubmed

Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.

CBLB PIK3R1

1.15e-045119224470255
Pubmed

The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase.

PIK3R1 LTK

1.15e-04511929223670
Pubmed

Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation.

CBLB PIK3R1

1.15e-045119210022120
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYBBP1A SMARCA5

1.15e-045119222147730
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

IRF2BP2 ATXN7L1 CHAMP1 CCNT1 BRD2 SLX4

1.20e-04222119637071664
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

APC2 CUL9 TSC2 KDM6B SHROOM2 DCAF5 BRD2 PIK3R1 MTMR3 RNF10 KCNQ2 CNOT3 SLX4 DKK3

1.31e-0412851191435914814
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

INPPL1 CHAF1A HCN3 DCAF5 CIC TNRC18 USP42 CASKIN2 RNF10 MLLT6

1.34e-046891191036543142
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ATXN2L ATN1 FBF1 APC2 TSC2 TACC2 FBLN2 SNAPC2 DKK3

1.38e-04560119921653829
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SPEG TSC2 CASKIN1 TJP2 BSN CEP170B

1.49e-04231119616452087
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

IRF2BP2 RTN4 TACC2 NIBAN2 ZYX CCNT1 NCOR2 SLX4

1.51e-04444119834795231
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ROCK2 ARFGEF1 RAPGEF1 NIBAN2 MICALL1 CASKIN2 PPP1R37 MICAL3 PLXNB1

1.55e-04569119930639242
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

FBF1 TSC2 ANAPC1 MTMR3 TJP2 SIPA1L2 FMNL1 CEP170B

1.56e-04446119824255178
Pubmed

A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation.

BACH2 NCF2 RNF10

1.64e-0431119332245826
Pubmed

A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.

CBLB PIK3R1

1.73e-046119211406619
Pubmed

cbl-b inhibits epidermal growth factor receptor signaling.

CBLB PIK3R1

1.73e-046119210086340
Pubmed

SHIP2 (SH2 domain-containing inositol phosphatase 2) SH2 domain negatively controls SHIP2 monoubiquitination in response to epidermal growth factor.

INPPL1 CBLB

1.73e-046119219880507
Pubmed

p85beta phosphoinositide 3-kinase regulates CD28 coreceptor function.

CBLB PIK3R1

1.73e-046119219190244
Pubmed

The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading.

INPPL1 PIK3R1

1.73e-046119215735664
Pubmed

Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo.

PIK3R1 LTK

1.73e-04611928084603
Pubmed

Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening.

CBLB TJP2

1.73e-046119212829691
InteractionTOP3B interactions

KMT2B KIF26A SPEG INPPL1 IRAK1 RAPGEF1 CUL9 TSC2 NUP214 FBXL19 KDM6B MBD6 CIC C6orf132 MICALL1 NCOR2 ORAI1 URB1 TNRC18 ARAP3 BRD2 ADAMTS7 CASKIN1 OSBPL5 MTMR3 KCNQ2 MLLT6 MICAL3 LTK SIPA1L2 CEP170B

1.39e-10147011631int:TOP3B
InteractionCDH1 interactions

ROCK2 ATXN2L RAPH1 INPPL1 CHAF1A RTN4 BAG3 IRAK1 NUP214 NIBAN2 ZYX ASAP1 C6orf132 MICALL1 CASKIN2 PIK3R1 PPP1R37 TJP2 CRYBG1

7.88e-0876811619int:CDH1
InteractionSH3KBP1 interactions

IRF2BP2 RAPH1 INPPL1 DAB2 CBLB ASAP1 MICALL1 TNRC18 ARAP3 CASKIN2 PIK3R1 TJP2

2.78e-0731511612int:SH3KBP1
InteractionYWHAE interactions

RAD52 ATXN2L CHAF1A BAG3 CAMSAP3 TSC2 TACC2 MBD6 SHROOM2 ZYX PABIR2 CIC C6orf132 MICALL1 CRY2 NCOR2 PIK3R1 MTMR3 TJP2 BRSK1 SIPA1L2 CEP170B

2.48e-06125611622int:YWHAE
InteractionNCK2 interactions

FAM47A ATN1 RAPH1 FBXL19 MBD6 CBLB ASAP1 CLEC17A CASKIN2 TJP2

2.83e-0626211610int:NCK2
InteractionVASP interactions

IRF2BP2 RAPH1 INPPL1 BAG3 IRAK1 ZYX C6orf132 TJP2 SIPA1L2 CEP170B

7.83e-0629411610int:VASP
InteractionNAA40 interactions

IRF2BP2 ATXN2L MYBBP1A SMARCA5 RAPH1 RTN4 NACA BAG3 IRAK1 TACC2 NUP214 NIBAN2 CHAMP1 ZYX CIC CCNT1 ZC3H4 SIPA1L2

1.19e-0597811618int:NAA40
InteractionFMR1 interactions

ROCK2 ATXN2L APC2 BAG3 TACC2 NCOR2 ANAPC1 CASKIN1 LTK BRSK1 BSN CNOT3 CEP170B

1.30e-0553611613int:FMR1
InteractionDYRK1A interactions

TSC2 NUP214 PABIR2 DCAF5 CIC NCOR2 ANAPC1 KNDC1 TJP2 SIPA1L2 CNOT3 SLX4 DKK3

1.78e-0555211613int:DYRK1A
InteractionCD2AP interactions

INPPL1 CBLB ZYX ASAP1 MICALL1 ARAP3 PIK3R1 TJP2

3.37e-052141168int:CD2AP
InteractionCBL interactions

RAPH1 INPPL1 FBF1 RAPGEF1 TSC2 CBLB ZYX ASAP1 PIK3R1 TJP2 LTK SP7

4.30e-0551611612int:CBL
InteractionH2BC21 interactions

ROCK2 SMARCA5 KMT2B ATXN7L1 CHAF1A KDM6B CHAMP1 MESD BRD2 USP42 ANAPC1 ZC3H4 CRYBG1 CCDC86

4.72e-0569611614int:H2BC21
InteractionTTC32 interactions

ATXN7L1 FBF1 BAG3

5.10e-05131163int:TTC32
InteractionCRKL interactions

BAG3 RAPGEF1 KDM6B CBLB ASAP1 CRY2 PIK3R1 SLX4

5.12e-052271168int:CRKL
InteractionSYNE3 interactions

FBF1 CAMSAP3 IRAK1 NUP214 NCOR2 MESD ANAPC1 NUP210 MTMR3 SIPA1L2 CEP170B

5.17e-0544411611int:SYNE3
InteractionYWHAH interactions

ATXN2L SPEG INPPL1 BAG3 CAMSAP3 TSC2 PABIR2 CIC C6orf132 MICALL1 MLXIPL CASKIN2 OSBPL5 MTMR3 RNF10 TJP2 SIPA1L2 CEP170B

5.76e-05110211618int:YWHAH
InteractionGRB2 interactions

INPPL1 FBF1 BAG3 DAB2 RAPGEF1 TSC2 CBLB SHROOM2 ASAP1 MLXIPL BRD2 PIK3R1 RNF10 LTK PLXNB1

6.03e-0580611615int:GRB2
InteractionYWHAZ interactions

RAD52 ATXN2L RAPH1 WDR7 SPEG CHAF1A BAG3 CAMSAP3 TSC2 TACC2 PABIR2 CIC C6orf132 MICALL1 MLXIPL PIK3R1 MTMR3 TJP2 SIPA1L2 CEP170B

6.04e-05131911620int:YWHAZ
InteractionYWHAG interactions

ATXN2L RAPH1 SPEG CHAF1A BAG3 CAMSAP3 TSC2 SHROOM2 PABIR2 CIC C6orf132 MICALL1 MLXIPL CASKIN2 PIK3R1 MTMR3 TJP2 SIPA1L2 CEP170B

8.97e-05124811619int:YWHAG
InteractionKDM1A interactions

TSHZ3 SMARCA5 KMT2B RAPH1 CHAF1A BAG3 CAMSAP3 IRAK1 NUP214 CHAMP1 CIC NCOR2 ANAPC1 RNF10 CNOT3 SP7

9.75e-0594111616int:KDM1A
InteractionCBFA2T2 interactions

IRF2BP2 ATN1 FBXL19 NCOR2

1.29e-04451164int:CBFA2T2
InteractionRCOR1 interactions

TSHZ3 SMARCA5 KMT2B RAPH1 BAG3 CAMSAP3 IRAK1 CIC NCOR2 ANAPC1 SP7

1.33e-0449411611int:RCOR1
InteractionFOXQ1 interactions

SMARCA5 CIC NCOR2 ANAPC1 MLLT6 CCDC86

1.66e-041411166int:FOXQ1
InteractionPFN1 interactions

RAD52 RAPH1 INPPL1 BAG3 C6orf132 CCNT1 PIK3R1 TJP2 MICAL3 SIPA1L2 FMNL1

1.73e-0450911611int:PFN1
Cytoband17q25.1

FBF1 CD300C CASKIN2

1.25e-0381119317q25.1
Cytoband9q34.13

NIBAN2 PRRT1B

1.35e-032111929q34.13
Cytoband10q26

TACC2 UTF1

1.63e-0323119210q26
Cytoband7q11.23

MLXIPL SRRM3 VPS37D

2.10e-039711937q11.23
CytobandEnsembl 112 genes in cytogenetic band chr10q26

BAG3 TACC2 KNDC1 UTF1

2.13e-032071194chr10q26
GeneFamilyZinc fingers CXXC-type

KMT2B FBXL19 TET3

1.85e-0512813136
GeneFamilySterile alpha motif domain containing

INPPL1 ARAP3 CASKIN2 CASKIN1

6.55e-0488814760
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ROCK2 RAPH1 ASAP1 ARAP3 OSBPL5

2.32e-03206815682
GeneFamilyLIM domain containing

ZYX MICALL1 MICAL3

2.35e-03598131218
CoexpressionGSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP

RAD52 ATXN2L TSPOAP1 BACH2 ZYX ASAP1 PPP1R37 SNAPC2

3.35e-062001178M6456
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

RAPH1 TSPOAP1 SPEG BACH2 RTN4 HCN3 APC2 ARFGEF1 TSC2 SHROOM2 CSPG5 CASKIN1 CACNA1I MICAL3 BSN SRRM3 PDZD4

8.43e-06110611717M39071
CoexpressionGSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN

IRF2BP2 ATXN2L TSPOAP1 NACA RAPGEF1 CBLB ORAI1

1.68e-051801177M8898
CoexpressionGSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP

ROCK2 B3GNT8 MICALL1 CCNT1 NCOR2 URB1 TJP2

1.74e-051811177M6849
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

ATXN2L ATN1 CUL9 NUP214 FBXL19 CIC MICALL1 ZNF580 CNOT3

2.16e-053381179M17094
CoexpressionGSE27786_CD8_TCELL_VS_NKTCELL_DN

RAPH1 ATXN7L1 PPM1J ARAP3 RNF10 PPP1R37 SP7

3.31e-052001177M4840
CoexpressionCHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP

CHAF1A MICALL1 URB1 ARAP3 ANAPC1 NUP210

4.88e-051451176M3045
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|GI_small-bowel / Manually curated celltypes from each tissue

RAPH1 ATXN7L1 BACH2 PIK3R1 CSPG5 OSBPL5

1.63e-06135118611a672ab6cba7026b8d81d8b216443cb88c0d47a
ToppCellTCGA-Adrenal|World / Sample_Type by Project: Shred V9

IGF2-AS PTPRN EGR4 DGKK INSM2 SRRM3

2.47e-061451186522ad2bc90b8ec326fcbc7b2250b09566efeeca2
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

ROCK2 TSHZ3 ASAP1 EGR4 LTK DKK3

4.21e-06159118618e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KMT2B TSPOAP1 CHAF1A PPM1J ZNF469 LTK

5.40e-061661186c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCellfacs-Heart-RA-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 SMARCA5 KDM6B ZYX RNF10 EPS8L3

8.05e-061781186b505e2550860e777535ee95f29c936242fd607f1
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A POU6F1 ARAP3 CASKIN2 TMEM132E TMEM245

8.31e-061791186025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HCN3 CAMSAP3 FBXL19 KCNQ2 BSN PDZD4

1.03e-0518611869d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 BAG3 KDM6B NCOR2 BRD2 DKK3

1.20e-0519111862f733d510a4862565a817f59829d8387d7ea26d9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 BAG3 KDM6B NCOR2 BRD2 DKK3

1.20e-0519111868691eba35793e4e90f93d50c2145847ee51289f7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROCK2 RAPH1 RTN4 ARFGEF1 NIBAN2 CRYBG1

1.24e-0519211862510f22197502f60fd266b7f42eff040f25b8ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROCK2 RAPH1 RTN4 ARFGEF1 NIBAN2 CRYBG1

1.24e-051921186e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 PTPRN KCNQ2 LTK BSN SRRM3

1.27e-051931186be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 PTPRN KCNQ2 LTK BSN SRRM3

1.27e-0519311860c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 PTPRN KCNQ2 LTK BSN SRRM3

1.27e-0519311868689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

RAPGEF1 ASAP1 ZNF469 FBLN2 BRD2 NUP210

1.39e-05196118609d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAPGEF1 KDM6B ASAP1 ZNF469 FMNL1 UTF1

1.43e-051971186515a2d0ee2bd3fc0a5a0c315e2b0c752e6af7406
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAPGEF1 KDM6B ASAP1 ZNF469 FMNL1 UTF1

1.43e-051971186bfa04e5f4156a01df4217b1f59676edb0a7563e1
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAPGEF1 KDM6B ASAP1 ZNF469 FMNL1 UTF1

1.43e-0519711864fccdc69ab4b966de6465f06677435e6f6e6abcd
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3 SP7

1.47e-051981186824461cf44098440ba8bc0df96735423ac65bda1
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BACH2 NUP210 TNFRSF13C MICAL3 FMNL1 SP7

1.47e-051981186863765ccc0205dc28864dae85af339c283194c96
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KDM6B ORAI1 BRD2 OSBPL5 FMNL1 PDZD4

1.52e-0519911860902b08e3386e64d7347c186d9ce5b67f2deaabb
ToppCellGlobus_pallidus|World / BrainAtlas - Mouse McCarroll V32

IRAK1 KDM6B MBD6 DGKK MLLT6

2.16e-05126118544b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

RTN4 DAB2 FBLN2 PIK3R1 DKK3

2.42e-05129118513cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Cerebellum / BrainAtlas - Mouse McCarroll V32

MYBBP1A PPM1J MESD ZNF469 SP7

2.90e-0513411858a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)|Cerebellum / BrainAtlas - Mouse McCarroll V32

MYBBP1A PPM1J MESD ZNF469 SP7

2.90e-0513411851fa13185a4dfb4563473184c0c4f449011d88631
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

MYBBP1A PPM1J MESD ZNF469 SP7

2.90e-0513411851ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCellTCGA-Peripheral_Nervous_System|World / Sample_Type by Project: Shred V9

IGF2-AS PTPRN EGR4 DGKK INSM2

4.10e-0514411853bbadb4b07ffb461d5400a5d69ad3b259f74041e
ToppCellDendritic_Cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

PPM1J ZNF469 CRYBG1 FMNL1 SLX4

5.14e-051511185e089bf197ed60e7243160521d4390d4b40a3832b
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 DAB2 NCF2 PABIR2 SRRM3

5.47e-0515311854b999892fb797e9f0d391630094f466463299d57
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 DAB2 NCF2 KNDC1 FOXI1

5.47e-051531185af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 DAB2 NCF2 KNDC1 FOXI1

5.47e-051531185984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 DAB2 NCF2 PABIR2 SRRM3

5.47e-051531185e426db29e4ba83e7930dc88c74fc975b177c9540
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 DAB2 NCF2 PABIR2 SRRM3

5.47e-051531185668eacd76aad6054bd7d57e3af0b122c2443465f
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

DAB2 KDM6B EGR4 TET3 CEP170B

5.47e-0515311855424494ea1f09542799045a875cc3eac13de5079
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

CHAF1A DAB2 C6orf132 FBLN2 LTK

6.96e-05161118551b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

CRY2 DGKK INSM2 SRRM3 PDZD4

6.96e-0516111855f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TSPOAP1 EGR4 PIK3R1 BRSK1 CEP170B

6.96e-0516111852fe77af3b41e6eacb707a64feea18f9991618173
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 PPM1J ZYX ARAP3 PIK3R1

7.38e-0516311852e1c1193c04620cc187b1567dfba025beef1e4e1
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2B INSM2 FMNL1 SLX4 CEP170B

7.38e-051631185953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR7 INSM2 SLX4 CEP170B PLXNB1

7.38e-051631185132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellfacs-Marrow-KLS-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APC2 DAB2 POU6F1 UTF1 DKK3

7.60e-051641185d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 AKAP4 USP42 LTK CEP170B

7.82e-0516511850edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 AKAP4 USP42 LTK CEP170B

7.82e-051651185fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

CHAF1A PPM1J FBLN2 TJP2 LTK

8.28e-051671185bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 PPM1J SHROOM2 ZYX ARAP3

8.28e-05167118592ddabbe55315856d8ea6f8db1560b6d97636bac
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

RAD52 TNRC18 TMEM132E PIK3R1 EPS8L3

8.51e-0516811852781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

CHAF1A PPM1J FBLN2 TJP2 LTK

8.51e-051681185968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 KIF26A SHROOM2 NCOR2 CASKIN2

1.03e-04175118598dc3b6f69a29d587f503898f09912700950e3d9
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-tDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DAB2 PPM1J FBLN2 EPS8L3 LTK

1.06e-041761185fb07a047a3a7a8d03bfcc28eea3da2eaa0f6b733
ToppCellAdult-Immune-B_cell|Adult / Lineage, Cell type, age group and donor

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.06e-0417611854aa00dcde907ad83d3aa4bb10439b7b5c4be1e5d
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.09e-041771185f54691e5558091c1734ab15153a10bff15ed171e
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.09e-041771185653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

TSPOAP1 CRY2 CASKIN2 MTMR3 MLLT6

1.09e-041771185e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellfacs-Lung-EPCAM-24m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 HCN3 CBLB MLLT6 UTF1

1.15e-04179118551872338e54c5f3e42ca9f1c4cf1e8b0cb84afcc
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 HCN3 CBLB MLLT6 UTF1

1.15e-0417911851b979e0203a2ddfe98bf6c2c80c4af1ba437a80f
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

SHROOM2 ARAP3 CASKIN2 LTK SIPA1L2

1.18e-041801185b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellChildren_(3_yrs)-Immune-B_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.18e-04180118540a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BACH2 FBLN2 CLEC17A TNFRSF13C MICAL3

1.21e-0418111856df40f86c569b6ecfc3137a68d1355b012dbf6bf
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.21e-0418111858d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCellremission-B_naive|remission / disease stage, cell group and cell class

BACH2 FBLN2 CLEC17A TNFRSF13C MICAL3

1.27e-041831185280d55d67f1d44594206da2f3a332c9d799dbdf0
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.30e-041841185911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.30e-041841185942b58ae7172bb5f97e55b032db9329d161854af
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c5-WDR74|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAPH1 DAB2 NCF2 NIBAN2 CD300C

1.34e-04185118568edb1bb03ed221d49e583123ca4de14252d7bc5
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KMT2B FBF1 TNRC18 FBLN2 USP42

1.34e-041851185daea170d827226dda6750bf1838ffd82f070c4d4
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPH1 BACH2 TACC2 KDM6B ORAI1

1.37e-04186118511929e36d8c9b4c4bc2f5e912f139f474f91ab00
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BACH2 KDM6B CLEC17A TNFRSF13C MICAL3

1.37e-0418611851a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BACH2 KDM6B CLEC17A TNFRSF13C MICAL3

1.37e-041861185f1366638edaecad5cad6367440f4c693513bed7e
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

BACH2 FBLN2 CLEC17A TNFRSF13C MICAL3

1.37e-041861185f352c63666273defea3e57ba3a3bfad52c4ea65b
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RTN4 EGR4 LTK FMNL1 DKK3

1.37e-04186118556c139e679d640ea901ead657a8e8887e0fca098
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN2L ATN1 KDM6B NCOR2 BRD2

1.37e-041861185bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellChildren_(3_yrs)-Immune-B_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.37e-041861185aa576748921a318798b911a611f05319b95e8d5e
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BACH2 FBLN2 CLEC17A TNFRSF13C MICAL3

1.37e-041861185e2d265003aaea1acaf618d3f102c9933c19102e6
ToppCellCOVID-19_Convalescent-Lymphoid_B-B_naive|COVID-19_Convalescent / Disease group, lineage and cell class

BACH2 FBLN2 CLEC17A TNFRSF13C MICAL3

1.37e-0418611859d339f57036d17572882ebb801f2be9b1d1ddc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 PTPRN KCNQ2 LTK BSN

1.37e-0418611857278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BACH2 FBLN2 CLEC17A TNFRSF13C MICAL3

1.41e-041871185e7970ec1507adfa91a296489166142cb9400421f
ToppCellLAM-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

IRF2BP2 CHAF1A DAB2 PPM1J LTK

1.41e-0418711854d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRF2BP2 BACH2 KDM6B CRYBG1 CACNA1I

1.44e-041881185939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APC2 PTPRN TMEM132E LTK SRRM3

1.44e-041881185bd091503f580dedab40e0996273101285d24b586
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPH1 BACH2 TACC2 KDM6B ORAI1

1.44e-041881185e0184d9f6687d7ecb8fc461294ff7208f49c437c
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_activate-7|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BACH2 KDM6B CLEC17A TNFRSF13C MICAL3

1.48e-041891185ef33cc03728a78423ee92d2ef1ffed4918d4221f
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NCF2 CD300C CRYBG1 FMNL1 UTF1

1.48e-041891185911bedfda2ae032bc8f18ee408d16926cda8ccc2
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN2L ATN1 KDM6B NCOR2 BRD2

1.48e-041891185965e0e388251e7318f8b463816dc96ccb4658677
ToppCellHSPCs-Ery_prog.|HSPCs / Lineage and Cell class

MYBBP1A NIBAN2 KDM6B ARAP3 BSN

1.48e-04189118537d2c45debed1564a40a1085b8b310c50923b9e7
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF26A APC2 DGKK BSN SRRM3

1.48e-041891185cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCellHippocampus-Neuronal-Excitatory|Hippocampus / BrainAtlas - Mouse McCarroll V32

ROCK2 EGR4 LTK FMNL1 DKK3

1.48e-0418911854b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TSPOAP1 CAMSAP3 KCNQ2 BSN PDZD4

1.52e-041901185416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NCF2 CD300C CLEC17A CRYBG1 FMNL1

1.52e-041901185eda2923e930e1094412088fd79c1e6a3b7db3b11
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

BACH2 RAPGEF1 CLEC17A TNFRSF13C MICAL3

1.52e-0419011851e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ZYX MESD PIK3R1 MICAL3 SRRM3

1.55e-041911185e7c605b56934d1383237c1f946dbccef25d91368
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NCF2 CD300C CRYBG1 FMNL1 UTF1

1.55e-04191118503e1ac489e918c7affc1cdc09fb3eb255bcf80e5
ToppCellCOVID-19_Mild-MAIT|COVID-19_Mild / Disease condition and Cell class

KDM6B B3GNT8 LTK SIPA1L2 DKK3

1.55e-041911185e834d7a6aa7bb4f194b203d351e53bf5d95175d6
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF2BP2 TACC2 CRY2 MLXIPL PTPRN

1.59e-0419211851304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

RTN4 NIBAN2 KDM6B ASAP1 C6orf132

1.59e-0419211858b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

RAPH1 RAPGEF1 SHROOM2 ASAP1 ARAP3

1.63e-04193118501c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

RAPH1 RAPGEF1 SHROOM2 ASAP1 ARAP3

1.63e-0419311852531266bc57339d4e2b22a88817008e32b8c1598
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BACH2 KDM6B CLEC17A TNFRSF13C MICAL3

1.67e-0419411855cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF2BP2 TACC2 CRY2 MLXIPL PTPRN

1.67e-04194118592b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BACH2 CLEC17A NUP210 TNFRSF13C MICAL3

1.71e-0419511853311a1bf4ed94820b45047d44fc14b14ac72e6fb
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

KDM6B CBLB PIK3R1 MICAL3 FMNL1

1.71e-0419511851470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APC2 PTPRN TMEM132E LTK SRRM3

1.71e-0419511855a6a5048af638872700b76b7c71a8fa3fb8d3772
Drugbromfenacoum

ROCK2 ATXN2L MYBBP1A RAPH1 RTN4 NACA BAG3 CAMSAP3 RAPGEF1 ZYX ANAPC1 CASKIN1 BSN CEP170B PLXNB1

1.11e-0664411715ctd:C013418
Drugclofibrate; Up 200; 150uM; MCF7; HG-U133A

ATXN2L ATN1 NCF2 MICALL1 MLXIPL CASKIN2 PPP1R37 CACNA1I

7.42e-061941178263_UP
DrugMethazolamide [554-57-4]; Down 200; 17uM; MCF7; HT_HG-U133A

KMT2B WDR7 NACA NUP214 ZYX MICALL1 CNOT3 PLXNB1

8.94e-0619911786268_DN
Drugexemestane; Down 200; 0.01uM; MCF7; HG-U133A

SMARCA5 KMT2B CHAF1A TSC2 ZYX CIC NUP210 ZNF580

8.94e-061991178165_DN
Diseasecomplex cortical dysplasia with other brain malformations (is_implicated_in)

KIF26A APC2

8.99e-0541152DOID:0090131 (is_implicated_in)
Diseaseage at diagnosis, type 2 diabetes mellitus

MLXIPL ZC3H4

8.99e-0541152EFO_0004918, MONDO_0005148
Diseaseresponse to antiviral drug, cirrhosis of liver

MLXIPL KCNQ2 VPS37D

1.10e-04241153EFO_0001422, EFO_0010123
DiseaseX-24328 measurement

MLXIPL VPS37D

3.12e-0471152EFO_0800873
DiseaseLeukemia, Myelocytic, Acute

BACH2 TSC2 NUP214 CBLB SLX4

5.97e-041731155C0023467
DiseaseGastric Adenocarcinoma

SPEG BRD2 BRSK1

7.26e-04451153C0278701
Diseaselean body mass

IGF2-AS APC2 NCOR2 MLXIPL ZC3H4 PIK3R1 MTMR3

7.29e-043791157EFO_0004995
Diseaseglucose measurement

RTN4 CRY2 ZC3H4 MTMR3 CACNA1I BSN SRRM3

7.40e-043801157EFO_0004468
Diseaseserum gamma-glutamyl transferase measurement

IRAK1 FBXL19 CBLB ZYX DCAF5 NCOR2 MLXIPL PIK3R1 MICAL3 SIPA1L2 VPS37D

9.03e-0491411511EFO_0004532
DiseaseCommon variable immunodeficiency

IRF2BP2 TNFRSF13C

1.14e-03131152cv:C0009447
Diseasemean reticulocyte volume

RAPH1 CHAF1A BACH2 IRAK1 MLXIPL ZNF469 PTPRN PIK3R1 VPS37D SP7

1.16e-0379911510EFO_0010701
Diseaseleft ventricular diastolic function measurement

BAG3 PIK3R1 SP7

1.24e-03541153EFO_0008204
Diseasemean corpuscular hemoglobin concentration

RAD52 IRF2BP2 ATN1 BACH2 TSC2 POU6F1 MLXIPL PIK3R1 MTMR3 CACNA1I VPS37D SP7

1.28e-03110511512EFO_0004528
Diseasesexual dimorphism measurement

ATXN2L IGF2-AS KMT2B RTN4 TSC2 NCOR2 MLXIPL ZC3H4 PIK3R1 CASKIN1 BSN VPS37D

1.29e-03110611512EFO_0021796
Diseasedystonia (is_implicated_in)

KMT2B TSPOAP1

1.33e-03141152DOID:543 (is_implicated_in)
Diseasecortical thickness

IRF2BP2 KMT2B CHAF1A CUL9 TACC2 MBD6 MICALL1 ZNF469 ADAMTS7 PIK3R1 MTMR3 MICAL3

1.36e-03111311512EFO_0004840
Diseasetestosterone measurement

IRF2BP2 ATXN2L NIBAN2 KDM6B CHAMP1 NCOR2 MLXIPL URB1 ANAPC1 ZC3H4 DGKK KNDC1 VPS37D

1.41e-03127511513EFO_0004908
DiseaseAutosomal Recessive Centronuclear Myopathy

SPEG ORAI1

1.53e-03151152C3645536
DiseaseCommon Variable Immunodeficiency

IRF2BP2 TNFRSF13C

1.53e-03151152C0009447
DiseaseSeizures

ATN1 APC2 TSC2 KCNQ2 TET3

1.67e-032181155C0036572
DiseaseCardiovascular Abnormalities

ATN1 APC2

1.74e-03161152C0243050
Diseasecentral nervous system disease (implicated_via_orthology)

IRF2BP2 SMARCA5

1.74e-03161152DOID:331 (implicated_via_orthology)
Diseasebitter alcoholic beverage consumption measurement

KDM6B CIC MLXIPL TET3

1.85e-031331154EFO_0010092
DiseaseVitiligo

BACH2 PIK3R1

1.97e-03171152C0042900
Diseaseserum alanine aminotransferase measurement

ATXN2L IRAK1 DCAF5 MLXIPL ADAMTS7 ZC3H4 PIK3R1 NUP210 TJP2 VPS37D

2.15e-0386911510EFO_0004735
Diseasecerebellum white matter volume change measurement, age at assessment

ADAMTS7 TJP2

2.73e-03201152EFO_0008007, EFO_0021498
Diseasecorneal hysteresis

ZNF469 ANAPC1

2.73e-03201152EFO_0010066
DiseaseOsteogenesis imperfecta

MESD SP7

3.01e-03211152cv:C0029434
DiseaseMalignant neoplasm of breast

RAPH1 APC2 TACC2 NUP214 SHROOM2 CIC MICALL1 ARAP3 MTMR3 PLXNB1 PDZD4

3.20e-03107411511C0006142
Diseasefat intake measurement

MLXIPL VPS37D

3.31e-03221152EFO_0010809
Diseasealcohol consumption measurement

ATXN2L RAPH1 KIF26A RTN4 MICALL1 NCOR2 MLXIPL ZC3H4 CACNA1I MICAL3 TET3 VPS37D

3.35e-03124211512EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
SPTRPPSPASAPKGF

nan

46

Q6ZS49
RKQPSPAPTPTAPAG

BACH2

311

Q9BYV9
KPTAPAPSAPPSPSA

MLLT6

371

P55198
LGSPERPPKTSPGSP

CCDC86

56

Q9H6F5
PPGPPSKSSPQARGS

ARAP3

1466

Q8WWN8
GPPSPTPGDKLSPAS

CSPG5

151

O95196
PSAPPAKPPSTQRAV

AKAP4

191

Q5JQC9
SGETAPPPPSPVSEK

ARFGEF1

1546

Q9Y6D6
GASGAPPTKPPTTPV

ATN1

266

P54259
RSGNTDKPRPPPLPS

CCNT1

701

O60563
SSPAARPSPEKVPPV

CEP170B

511

Q9Y4F5
SSTSSPEGPPAPPKQ

CHAF1A

291

Q13111
PGPTTGPKAASPSPA

CAMSAP3

746

Q9P1Y5
GPEPKVASPAKSRPP

ATXN7L1

381

Q9ULK2
LAPRPSPASSPKPGT

ADAMTS7

1026

Q9UKP4
PPRSPKSAAPAPISA

ATXN2L

446

Q8WWM7
PGESAPRKESPRPPA

ATP1A1-AS1

16

Q5TC04
PSVTRKDSPEPSPHP

CD300C

161

Q08708
PAAPPSALGPKASPA

CNOT3

346

O75175
KPPLASAEGPAVPSP

FBXL19

286

Q6PCT2
PPPPTASPTPDKSGS

RAPH1

941

Q70E73
PPAESGSPSKETLPP

RAPH1

1006

Q70E73
TPSAEKSEAAPPAPP

RAD52

281

P43351
PPGSPGRCTPKSSEP

TSPOAP1

571

O95153
SPQPKAAPEASSPPA

NIBAN2

681

Q96TA1
PRPSTPLDGVSTPKP

ANAPC1

526

Q9H1A4
PTSPNALPPARKASP

NUP210

1861

Q8TEM1
QPPPRAGPPKDISSD

DAB2

621

P98082
AKSPAPGLASGDRPP

NCOR2

2411

Q9Y618
GTPPSLGASPAKPPS

CASKIN1

1316

Q8WXD9
RGLKTSPSPSPSPSP

DGKK

191

Q5KSL6
SVPGAPAPPAASKAP

MBD6

471

Q96DN6
SPVSSEPPKAARPPV

PTPRN

426

Q16849
SKGPEPSFPTPAFRP

MICAL3

1346

Q7RTP6
DIPAPPSSKAPGRPQ

NCF2

316

P19878
GSPGTPDESTPPPRK

MESD

36

Q14696
ASKAKPPTAPAPPSA

KDM6B

1041

O15054
KPSTAEPRPPAGEAP

BSN

311

Q9UPA5
SDGSQAPARPPKPRP

CBLB

896

Q13191
PGQPRPTSKPPASGA

ORAI1

206

Q96D31
LASPSPRDPKVSAPP

LTK

36

P29376
QAVPGSPRDPVKPSP

FBLN2

371

P98095
ARGGPSPSPPTAPKA

PLXNB1

686

O43157
SPSPPTAPKALATPA

PLXNB1

691

O43157
SGLAFRKDPPPEPSP

KCNQ2

401

O43526
PEPSPSKGSPCRGPL

KCNQ2

411

O43526
VATPAKAAPPPGSPA

PDZD4

511

Q76G19
PGDPNSRPSSPKPAQ

EPS8L3

436

Q8TE67
SSRAEEPPSPPVPKA

DCAF5

786

Q96JK2
EPPSPPVPKASGSTL

DCAF5

791

Q96JK2
PPVAVRKPSTPESPA

POU6F1

66

Q14863
SPRITPPAAKPGSPQ

NUP214

666

P35658
PSGAAPPAPPTRKSS

KIF26A

1356

Q9ULI4
PPAGRPTPAPRKASE

MICALL1

296

Q8N3F8
SLGPAPEPPKPATSK

KMT2B

2176

Q9UMN6
SPPDVKPGLRAPPAS

EGR4

281

Q05215
PPRPLPVAPGSSKTE

PIK3R1

91

P27986
APPPATAASGPIPKS

HCN3

26

Q9P1Z3
PPSPAPSSTKPGPES

IRAK1

171

P51617
PSPSPSPAKPAGAEL

INSM2

106

Q96T92
PPPKRLSSVSGPSPE

CASKIN2

871

Q8WXE0
KSPAPGAPTRSPSTP

MYBBP1A

1231

Q9BQG0
PKRIDFTPVSPAPSP

PABIR2

106

Q7Z309
GSPSPASPPADGRLK

PPP1R37

26

O75864
PPRSPAEPKGSALGP

C6orf132

276

Q5T0Z8
VGPSESKPRGPSPLP

ERVK-5

171

Q9HDB9
PSKAAPAAPPPARTQ

APC2

1551

O95996
PGPGASPVPKTPART

APC2

1901

O95996
PAGLPPSRAKPPTEG

FBF1

386

Q8TES7
PSRAKPPTEGAGSPA

FBF1

391

Q8TES7
SKGPQSAPPSPPAGR

IGF2-AS

126

Q6U949
SAGPRPLPSGPASPK

CRY2

546

Q49AN0
PVFPETRKPGPSGPS

CHAMP1

491

Q96JM3
PPPAPGLTPARKFSS

CACNA1I

2141

Q9P0X4
PTTEAPPLPPRNAGK

ASAP1

786

Q9ULH1
PDPELSSSPRRGPPK

BRSK1

751

Q8TDC3
EPEKAPPAAPTRPSA

FMNL1

461

O95466
PPKTRRTSSLGPEPP

FAM47A

521

Q5JRC9
AAPGSPVPAPPTKAS

KNDC1

776

Q76NI1
PGPSPEPSTRPFSKN

CUL9

1436

Q8IWT3
TSSPEKRPSPPPSGA

FOXI1

261

Q12951
AVPAPPASGPRAPAK

CRYBG1

116

Q9Y4K1
PASGPRAPAKESPPK

CRYBG1

121

Q9Y4K1
LSKAYPSPRGTPPSP

B3GNT8

31

Q7Z7M8
AAPSTAPAEATPPKP

BAG3

396

O95817
PAPAPTATSAPVKPG

DKK3

21

Q9UBP4
SPPGAAASAAAKPPP

IRF2BP2

71

Q7Z5L9
PGTSPDDPPLSRLPK

MTMR3

596

Q13615
GPPTPSSATKVPPAE

OSBPL5

61

Q9H0X9
PAAPPSTPAAPKRRG

RTN4

166

Q9NQC3
AHSPPDKPSSPSPRV

SRRM3

331

A6NNA2
PPARGKESPSPRSAP

SRRM3

356

A6NNA2
GPPAPAAPPTARRKS

TMEM132E

201

Q6IEE7
PAAAPEAPRSPPAKA

PPM1J

36

Q5JR12
VSRSKDVPPFGPPIP

SIPA1L2

751

Q9P2F8
PPSPARAPVPSATKN

INPPL1

1001

O15357
PPPPPLRSDSFAATK

SHROOM2

316

Q13796
PAPSPRGQKASPPTL

MLXIPL

496

Q9NP71
RAGPATSPPKTPPQL

URB1

1091

O60287
TPPSRSPTKEAPPGL

SLX4

1676

Q8IY92
SPPGSLEPKAARLPP

BRD2

301

P25440
KGPPAPATATPAPTS

CIC

1136

Q96RK0
KPGSSAPPRPPRAAK

CLEC17A

91

Q6ZS10
SPPPSPRASPVAALK

TNRC18

991

O15417
PTPGARGPDPSSPDK

TNRC18

1946

O15417
STKKAPPPRDPGTPA

USP42

771

Q9H9J4
PPPRDPGTPATKEGA

USP42

776

Q9H9J4
KPDPGTPQHTSSRPP

TJP2

1126

Q9UDY2
DAGTRAPPSPGVPPK

SPEG

11

Q15772
GRPSPTSPVKPSSPA

RAPGEF1

211

Q13905
PSSPASKPDGPAELP

RAPGEF1

221

Q13905
PRPSASPATPEKAPG

SP7

406

Q8TDD2
PPRSASAGPAGESKP

RNF10

36

Q8N5U6
KPPAPDPFARSSPRT

ROCK2

1351

O75116
PKAPSESARGPPGPT

TACC2

536

O95359
PAPTSAADPPKSFPA

VPS37D

181

Q86XT2
KVEAPSSSPAPAPSP

TET3

491

O43151
PDGKLSPPKRATPSP

TSHZ3

631

Q63HK5
KCGSDSTPPPPLPRR

nan

46

Q8N1X5
KPGPAEAPSPTASPS

ZC3H4

1096

Q9UPT8
TPAKPSFPSRSPAPE

ZNF469

3736

Q96JG9
GPKDAPSLRSSPGPA

TMEM245

6

Q9H330
PASSPAPAPKFSPVT

ZYX

256

Q15942
PPPESAPSKPAASIA

SMARCA5

11

O60264
APPFPKAEGPSSTPS

ZNF580

26

Q9UK33
PRPKPAGASSPAPRT

TNFRSF13C

41

Q96RJ3
GSPATPEDPRSPAKP

PRRT1B

16

A0A1B0GWB2
KGPTRPPRPSTPDLS

WDR7

916

Q9Y4E6
SSAPRTPDPAPEKPS

SNAPC2

176

Q13487
PAASTAKPPPLPRSN

TSC2

1256

P49815
PSPPKSADASPAPGS

UTF1

206

Q5T230
VARKPSVGVPPPASP

KIAA1522

966

Q9P206
ATPSPKGAPTPPAVT

NACA

1001

E9PAV3
TPFPKGASTPPAATP

NACA

1026

E9PAV3
GASTPPAATPPSPKG

NACA

1031

E9PAV3
PAATPPSPKGSPAAT

NACA

1036

E9PAV3
SPAATPLPKGAPTTP

NACA

1046

E9PAV3
PATPSLKGAPTPPAA

NACA

1071

E9PAV3
PAATPPSPKGGLATP

NACA

1106

E9PAV3
PTTPAATPPSPKGGL

NACA

1126

E9PAV3
ATPPPKGAPTTPAAT

NACA

1141

E9PAV3
APTTPAATPPSPKGG

NACA

1171

E9PAV3
GAPTTPAATPPSPKG

NACA

1216

E9PAV3
PAATPPSPKGGLATP

NACA

1221

E9PAV3
VVTPPSPKGGPATSP

NACA

1291

E9PAV3
RGPAIPSPKGDPTSP

NACA

1391

E9PAV3
SKGDPTLPAVTPPSP

NACA

1461

E9PAV3