| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP ZNF630 CTCFL ZNF23 ZNF28 ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 NFXL1 ZNF432 KDM2B ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 1.07e-35 | 1459 | 118 | 59 | GO:0000977 |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ISL2 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP ZNF630 CTCFL ZNF23 ZNF28 ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 NFXL1 ZNF432 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 2.32e-35 | 1412 | 118 | 58 | GO:0000981 |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | ZNF410 ZNF311 ZNF577 ZNF652 ZNF485 ISL2 ZNF880 ZNF621 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF829 ZNF260 ZNF675 HINFP ZNF630 CTCFL ZNF23 ZNF28 KLF10 CTCF ZNF41 ZNF257 GLI1 ZNF483 ZNF432 KDM2B ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 GLIS1 ZNF639 ZNF572 | 6.93e-25 | 1271 | 118 | 46 | GO:0000987 |
| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | ZNF410 ZNF311 ZNF577 ZNF652 ZNF485 ZNF880 ZNF621 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF829 ZNF260 ZNF675 HINFP ZNF630 CTCFL ZNF23 ZNF28 KLF10 CTCF ZNF41 ZNF257 GLI1 ZNF483 ZNF432 KDM2B ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 GLIS1 ZNF639 ZNF572 | 2.76e-24 | 1244 | 118 | 45 | GO:0000978 |
| GeneOntologyMolecularFunction | DNA-binding transcription repressor activity | ZNF101 YY1 GFI1 HINFP ZNF28 CTCF ZNF782 ZKSCAN4 ZNF418 ZNF281 ZNF709 GLIS1 ZNF572 | 6.89e-08 | 326 | 118 | 13 | GO:0001217 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity | ZNF485 ZNF101 ZNF519 YY1 ZNF786 HINFP BNC1 CTCFL KLF10 CTCF GLI1 ZNF615 ZNF782 ZNF709 GLIS1 ZNF639 | 2.27e-07 | 566 | 118 | 16 | GO:0001216 |
| GeneOntologyMolecularFunction | DNA-binding transcription repressor activity, RNA polymerase II-specific | ZNF101 YY1 GFI1 HINFP ZNF28 CTCF ZNF782 ZKSCAN4 ZNF281 ZNF709 GLIS1 ZNF572 | 4.37e-07 | 320 | 118 | 12 | GO:0001227 |
| GeneOntologyMolecularFunction | GTPase activator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 8.30e-07 | 279 | 118 | 11 | GO:0005096 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity, RNA polymerase II-specific | ZNF485 ZNF101 ZNF519 YY1 ZNF786 HINFP CTCFL KLF10 CTCF GLI1 ZNF615 ZNF782 ZNF709 GLIS1 ZNF639 | 1.10e-06 | 560 | 118 | 15 | GO:0001228 |
| GeneOntologyMolecularFunction | damaged DNA binding | ZNF101 ZNF28 ZNF432 ZNF782 ZNF709 | 1.41e-04 | 84 | 118 | 5 | GO:0003684 |
| GeneOntologyMolecularFunction | nucleoside-triphosphatase regulator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 2.10e-04 | 507 | 118 | 11 | GO:0060589 |
| GeneOntologyMolecularFunction | GTPase regulator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 2.10e-04 | 507 | 118 | 11 | GO:0030695 |
| GeneOntologyMolecularFunction | chromatin insulator sequence binding | CTCFL CTCF | 7.13e-04 | 7 | 118 | 2 | GO:0043035 |
| GeneOntologyMolecularFunction | zinc ion binding | ZFAND2A ZCCHC8 ZCCHC17 FBXL19 ZKSCAN5 ZNF675 PIKFYVE CTCF AOPEP ITGB1BP2 MIB1 NFXL1 KDM2B ZNF84 | 7.85e-04 | 891 | 118 | 14 | GO:0008270 |
| GeneOntologyMolecularFunction | unmethylated CpG binding | FBXL19 KDM2B | 1.51e-03 | 10 | 118 | 2 | GO:0045322 |
| GeneOntologyMolecularFunction | transition metal ion binding | ZFAND2A DPYD ZCCHC8 ZCCHC17 FBXL19 ZKSCAN5 ZNF675 PIKFYVE MGAT2 CTCF AOPEP ITGB1BP2 MIB1 NFXL1 KDM2B ZNF84 | 1.69e-03 | 1189 | 118 | 16 | GO:0046914 |
| GeneOntologyMolecularFunction | enzyme activator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 1.76e-03 | 656 | 118 | 11 | GO:0008047 |
| GeneOntologyMolecularFunction | molecular function activator activity | TBC1D3E SEMA3C TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B NSD3 WNT5B EFEMP1 TBC1D3I IL1RN TBC1D3G TBC1D3K TBC1D3F | 2.44e-03 | 1233 | 118 | 16 | GO:0140677 |
| GeneOntologyBiologicalProcess | activation of GTPase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 2.92e-11 | 109 | 117 | 11 | GO:0090630 |
| GeneOntologyBiologicalProcess | positive regulation of GTPase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 1.46e-07 | 244 | 117 | 11 | GO:0043547 |
| GeneOntologyBiologicalProcess | regulation of GTPase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 3.30e-06 | 335 | 117 | 11 | GO:0043087 |
| GeneOntologyBiologicalProcess | positive regulation of hydrolase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B CYCS TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 2.70e-05 | 499 | 117 | 12 | GO:0051345 |
| Domain | - | CBLL1 ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 9.06e-57 | 679 | 116 | 61 | 3.30.160.60 |
| Domain | zf-C2H2 | ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP BNC1 ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 3.20e-56 | 693 | 116 | 61 | PF00096 |
| Domain | Znf_C2H2/integrase_DNA-bd | CBLL1 ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 3.50e-56 | 694 | 116 | 61 | IPR013087 |
| Domain | ZINC_FINGER_C2H2_2 | CBLL1 ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP BNC1 ZC3H7A ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 3.73e-56 | 775 | 116 | 63 | PS50157 |
| Domain | ZINC_FINGER_C2H2_1 | CBLL1 ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP BNC1 ZC3H7A ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 4.40e-56 | 777 | 116 | 63 | PS00028 |
| Domain | Znf_C2H2-like | CBLL1 ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP BNC1 ZC3H7A ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 2.03e-55 | 796 | 116 | 63 | IPR015880 |
| Domain | ZnF_C2H2 | CBLL1 ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP BNC1 ZC3H7A ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 5.23e-55 | 808 | 116 | 63 | SM00355 |
| Domain | Znf_C2H2 | ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP BNC1 ZC3H7A ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 1.16e-53 | 805 | 116 | 62 | IPR007087 |
| Domain | KRAB | ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF674 ZNF485 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF251 ZKSCAN5 ZNF786 ZNF441 ZNF829 ZNF404 ZNF77 ZNF563 ZNF675 ZNF630 ZNF23 ZNF28 ZNF550 ZNF41 ZNF257 ZNF425 ZNF483 ZNF432 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF418 ZNF709 ZNF614 | 1.34e-39 | 358 | 116 | 40 | PS50805 |
| Domain | KRAB | ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF674 ZNF485 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF251 ZKSCAN5 ZNF786 ZNF441 ZNF829 ZNF404 ZNF77 ZNF563 ZNF675 ZNF630 ZNF23 ZNF28 ZNF550 ZNF41 ZNF257 ZNF425 ZNF483 ZNF432 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF418 ZNF709 ZNF614 | 4.61e-39 | 369 | 116 | 40 | SM00349 |
| Domain | KRAB | ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF674 ZNF485 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF251 ZKSCAN5 ZNF786 ZNF441 ZNF829 ZNF404 ZNF77 ZNF563 ZNF675 ZNF630 ZNF23 ZNF28 ZNF550 ZNF41 ZNF257 ZNF425 ZNF483 ZNF432 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF418 ZNF709 ZNF614 | 5.15e-39 | 370 | 116 | 40 | IPR001909 |
| Domain | KRAB | ZNF311 ZNF577 ZNF560 ZNF337 ZNF674 ZNF485 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF251 ZKSCAN5 ZNF786 ZNF441 ZNF829 ZNF404 ZNF77 ZNF563 ZNF675 ZNF630 ZNF28 ZNF550 ZNF41 ZNF257 ZNF425 ZNF483 ZNF432 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF418 ZNF709 ZNF614 | 1.14e-36 | 358 | 116 | 38 | PF01352 |
| Domain | zf-C2H2_6 | ZNF311 ZNF266 ZNF560 ZNF652 ZBTB47 ZNF880 ZNF621 ZNF302 ZNF865 ZNF251 ZKSCAN5 GFI1 ZNF404 ZNF260 ZNF77 ZNF675 ZNF425 ZNF483 ZNF432 ZNF799 ZNF84 ZNF615 ZNF782 ZKSCAN4 ZNF418 ZNF709 ZFP2 ZNF572 | 9.88e-25 | 314 | 116 | 28 | PF13912 |
| Domain | TBC | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 3.86e-13 | 49 | 116 | 10 | SM00164 |
| Domain | RabGAP-TBC | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 8.97e-13 | 53 | 116 | 10 | PF00566 |
| Domain | TBC_RABGAP | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 1.33e-12 | 55 | 116 | 10 | PS50086 |
| Domain | Rab-GTPase-TBC_dom | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 1.33e-12 | 55 | 116 | 10 | IPR000195 |
| Domain | Growth_fac_rcpt_ | PCSK5 FRAS1 TNC FBXL19 EYS EFEMP1 LTBP2 | 5.40e-05 | 156 | 116 | 7 | IPR009030 |
| Domain | EGF | PCSK5 FRAS1 TNC EYS EFEMP1 CELSR3 PLAU LTBP2 | 1.10e-04 | 235 | 116 | 8 | SM00181 |
| Domain | PHD_4 | FBXL19 KDM2B | 1.14e-04 | 3 | 116 | 2 | PF16866 |
| Domain | EGF-like_dom | PCSK5 FRAS1 TNC EYS EFEMP1 CELSR3 PLAU LTBP2 | 1.64e-04 | 249 | 116 | 8 | IPR000742 |
| Domain | Znf_CXXC | FBXL19 KDM2B | 2.03e-03 | 11 | 116 | 2 | IPR002857 |
| Domain | ZF_CXXC | FBXL19 KDM2B | 2.03e-03 | 11 | 116 | 2 | PS51058 |
| Domain | zf-CXXC | FBXL19 KDM2B | 2.03e-03 | 11 | 116 | 2 | PF02008 |
| Pathway | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION | ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF485 ZNF621 ZNF101 ZNF302 ZNF519 YY1 ZKSCAN5 ZNF786 ZNF441 ZNF77 ZNF563 ZNF675 ZNF23 ZNF28 ZNF550 ZNF41 ZNF257 ZNF425 CYCS ZNF483 ZNF432 ZNF799 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF709 ZFP2 ZNF614 | 2.38e-15 | 1387 | 84 | 36 | M734 |
| Pathway | WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K | 6.84e-09 | 99 | 84 | 9 | M46448 |
| Pathway | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | ZNF101 ZNF519 ZKSCAN5 ZNF786 ZNF563 ZNF23 ZNF28 CTCF CYCS ZNF483 ZNF799 ZNF221 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF709 ZFP2 | 4.66e-07 | 768 | 84 | 18 | MM14851 |
| Pathway | REACTOME_GENE_EXPRESSION_TRANSCRIPTION | ZNF101 ZNF519 ZKSCAN5 ZNF786 ZNF563 ZNF23 ZNF28 GTF3A CTCF CYCS ZNF483 ZNF799 ZNF221 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF709 ZFP2 | 6.73e-06 | 1022 | 84 | 19 | MM15436 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS | ZCCHC8 ZNF519 ZNF28 ZNF257 ZNF425 ZNF418 | 2.00e-04 | 142 | 84 | 6 | M48257 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS | ZNF101 ZNF28 ZNF782 ZNF709 | 3.40e-04 | 56 | 84 | 4 | MM17236 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_KRAB_ZFP_PROTEINS | ZNF519 ZNF28 ZNF257 ZNF425 ZNF418 | 4.40e-04 | 107 | 84 | 5 | M48260 |
| Pubmed | TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12. | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 4.68e-28 | 11 | 119 | 11 | 16863688 |
| Pubmed | Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells. | ZNF311 ZCCHC8 ZNF485 ZNF57 ZNF101 ZNF441 ZNF77 ZNF563 ZNF550 ZNF41 ZNF257 ZNF432 ZNF799 ZNF84 ZNF615 ZNF614 | 2.49e-18 | 181 | 119 | 16 | 37372979 |
| Pubmed | DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. | TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F | 6.84e-09 | 74 | 119 | 7 | 16625196 |
| Pubmed | Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. | ZNF410 ISL2 FBXL19 YY1 ZNF786 ZNF260 HINFP IBTK GTF3A KLF10 CTCF JAZF1 ZKSCAN4 GLIS1 ZNF639 | 1.20e-07 | 808 | 119 | 15 | 20412781 |
| Pubmed | PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. | TBC1D3 TBC1D3D TBC1D3F | 1.56e-07 | 4 | 119 | 3 | 12359748 |
| Pubmed | Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes. | TBC1D3 TBC1D3D TBC1D3F | 1.56e-07 | 4 | 119 | 3 | 8406013 |
| Pubmed | The Tre2 (USP6) oncogene is a hominoid-specific gene. | TBC1D3 TBC1D3D TBC1D3C | 3.89e-07 | 5 | 119 | 3 | 12604796 |
| Pubmed | Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes. | TBC1D3 TBC1D3D TBC1D3F | 3.89e-07 | 5 | 119 | 3 | 8471161 |
| Pubmed | A census of human transcription factors: function, expression and evolution. | ZNF410 ISL2 YY1 HINFP BNC1 CTCFL ZNF23 ZNF28 KLF10 CTCF GLI1 NFXL1 JAZF1 ZNF281 GLIS1 | 5.28e-07 | 908 | 119 | 15 | 19274049 |
| Pubmed | Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 28145452 |
| Pubmed | CTCF and CTCFL in cancer. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 32334335 |
| Pubmed | PLAU is associated with cell migration and invasion and is regulated by transcription factor YY1 in cervical cancer. | YY1 PLAU | 1.16e-05 | 2 | 119 | 2 | 36524374 |
| Pubmed | The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 12191639 |
| Pubmed | Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 32393311 |
| Pubmed | CTCF is required for maintenance of auditory hair cells and hearing function in the mouse cochlea. | GFI1 CTCF | 1.16e-05 | 2 | 119 | 2 | 30107916 |
| Pubmed | YY1 and CTCF orchestrate a 3D chromatin looping switch during early neural lineage commitment. | YY1 CTCF | 1.16e-05 | 2 | 119 | 2 | 28536180 |
| Pubmed | The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 22709888 |
| Pubmed | The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 34158481 |
| Pubmed | Discovering a binary CTCF code with a little help from BORIS. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 29077515 |
| Pubmed | BORIS and CTCF are overexpressed in squamous intraepithelial lesions and cervical cancer. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 26125810 |
| Pubmed | The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 23553099 |
| Pubmed | Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. | YY1 CTCF | 1.16e-05 | 2 | 119 | 2 | 17218270 |
| Pubmed | BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. | CTCFL CTCF | 1.16e-05 | 2 | 119 | 2 | 12011441 |
| Pubmed | EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. | FRAS1 CTCF KDM2B ZNF281 | 1.59e-05 | 44 | 119 | 4 | 27505670 |
| Pubmed | Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics. | ZNF432 ZNF614 | 3.47e-05 | 3 | 119 | 2 | 24280104 |
| Pubmed | Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma. | CTCFL CTCF | 3.47e-05 | 3 | 119 | 2 | 22544282 |
| Pubmed | BORIS Expression in Ovarian Cancer Precursor Cells Alters the CTCF Cistrome and Enhances Invasiveness through GALNT14. | CTCFL CTCF | 3.47e-05 | 3 | 119 | 2 | 31292201 |
| Pubmed | Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells. | CTCFL CTCF | 3.47e-05 | 3 | 119 | 2 | 16140944 |
| Pubmed | GFI1 functions to repress neuronal gene expression in the developing inner ear hair cells. | GFI1 GLI1 | 3.47e-05 | 3 | 119 | 2 | 32917668 |
| Pubmed | Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A. | PCSK5 LTBP2 | 3.47e-05 | 3 | 119 | 2 | 21700711 |
| Pubmed | Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer. | CTCFL CTCF | 3.47e-05 | 3 | 119 | 2 | 25499215 |
| Pubmed | CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer. | CTCFL CTCF | 3.47e-05 | 3 | 119 | 2 | 21325284 |
| Pubmed | Diversity of human copy number variation and multicopy genes. | TBC1D3E TBC1D3G | 3.47e-05 | 3 | 119 | 2 | 21030649 |
| Pubmed | RPL35A drives ovarian cancer progression by promoting the binding of YY1 to CTCF promoter. | YY1 CTCF | 3.47e-05 | 3 | 119 | 2 | 38436544 |
| Pubmed | Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress. | CTCFL CTCF | 3.47e-05 | 3 | 119 | 2 | 33411704 |
| Pubmed | CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. | YY1 CTCF | 3.47e-05 | 3 | 119 | 2 | 21606361 |
| Pubmed | Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage. | CTCFL CTCF | 3.47e-05 | 3 | 119 | 2 | 21296871 |
| Pubmed | Enhancer-promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1. | YY1 CTCF | 3.47e-05 | 3 | 119 | 2 | 36471071 |
| Pubmed | Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation. | GFI1 GLI1 | 3.47e-05 | 3 | 119 | 2 | 12049724 |
| Pubmed | Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1). | GLI1 GLIS1 | 3.47e-05 | 3 | 119 | 2 | 18263616 |
| Pubmed | Coding region intron/exon organization, alternative splicing, and X-chromosome inactivation of the KRAB/FPB-domain-containing human zinc finger gene ZNF41. | ZNF41 ZNF221 | 3.47e-05 | 3 | 119 | 2 | 10449920 |
| Pubmed | An atlas of combinatorial transcriptional regulation in mouse and man. | ZNF410 ISL2 FBXL19 ZNF519 YY1 ZKSCAN5 GFI1 ZNF23 ZNF41 GLI1 KDM2B ZFP2 | 4.93e-05 | 877 | 119 | 12 | 20211142 |
| Pubmed | Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. | ZNF266 ZNF302 ZNF23 | 4.97e-05 | 21 | 119 | 3 | 7865130 |
| Pubmed | The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification. | ZNF577 ZNF84 ZKSCAN4 | 5.74e-05 | 22 | 119 | 3 | 31403225 |
| Pubmed | XLID-causing mutations and associated genes challenged in light of data from large-scale human exome sequencing. | ZNF674 ZNF41 | 6.93e-05 | 4 | 119 | 2 | 23871722 |
| Pubmed | Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis. | FRAS1 GLI1 | 6.93e-05 | 4 | 119 | 2 | 36495293 |
| Pubmed | Members of the zinc finger protein gene family sharing a conserved N-terminal module. | ZNF41 ZNF84 | 6.93e-05 | 4 | 119 | 2 | 1945843 |
| Pubmed | Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages. | TNC GLI1 | 6.93e-05 | 4 | 119 | 2 | 38241368 |
| Pubmed | Bergmann glial Sonic hedgehog signaling activity is required for proper cerebellar cortical expansion and architecture. | TNC GLI1 | 1.15e-04 | 5 | 119 | 2 | 29792854 |
| Pubmed | DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. | CTCFL CTCF | 1.15e-04 | 5 | 119 | 2 | 18413740 |
| Pubmed | The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. | YY1 CTCF | 1.15e-04 | 5 | 119 | 2 | 19536159 |
| Pubmed | RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6. | GLI1 GLIS1 | 1.73e-04 | 6 | 119 | 2 | 33895473 |
| Pubmed | A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development. | GLI1 GLIS1 | 1.73e-04 | 6 | 119 | 2 | 12385751 |
| Pubmed | Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. | DPYD SEMA3C ZNF101 ESCO2 | 2.33e-04 | 87 | 119 | 4 | 33798452 |
| Pubmed | A role for hedgehog signaling in the differentiation of the insertion site of the patellar tendon in the mouse. | TNC GLI1 | 2.41e-04 | 7 | 119 | 2 | 23762363 |
| Pubmed | Expression of secreted semaphorins and their receptors in specific neuromeres, boundaries, and neuronal groups in the developing mouse and chick brain. | SEMA3C ISL2 | 2.41e-04 | 7 | 119 | 2 | 16360650 |
| Pubmed | The Purkinje neuron acts as a central regulator of spatially and functionally distinct cerebellar precursors. | TNC GLI1 | 2.41e-04 | 7 | 119 | 2 | 24229643 |
| Pubmed | The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. | SEMA3C FRAS1 TNC EFEMP1 LTBP2 | 2.82e-04 | 167 | 119 | 5 | 22159717 |
| Pubmed | Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis. | YY1 CTCFL NFXL1 | 3.02e-04 | 38 | 119 | 3 | 28218735 |
| Pubmed | CTCF regulates the local epigenetic state of ribosomal DNA repeats. | CTCFL CTCF | 3.21e-04 | 8 | 119 | 2 | 21059229 |
| Pubmed | Proviral integrations at the Evi5 locus disrupt a novel 90 kDa protein with homology to the Tre2 oncogene and cell-cycle regulatory proteins. | GFI1 GLI1 | 4.11e-04 | 9 | 119 | 2 | 9070650 |
| Pubmed | Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. | ISL2 GLI1 | 4.11e-04 | 9 | 119 | 2 | 12361967 |
| Pubmed | Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. | ISL2 GLI1 | 4.11e-04 | 9 | 119 | 2 | 10725236 |
| Pubmed | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. | FBXL19 KDM2B | 5.13e-04 | 10 | 119 | 2 | 29276034 |
| Pubmed | Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification. | ISL2 GLI1 | 5.13e-04 | 10 | 119 | 2 | 12812795 |
| Pubmed | Development of migrating tendon-bone attachments involves replacement of progenitor populations. | TNC GLI1 | 5.13e-04 | 10 | 119 | 2 | 30504126 |
| Pubmed | The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation. | CTCFL CTCF | 5.13e-04 | 10 | 119 | 2 | 17048991 |
| Pubmed | Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling. | TNC GLI1 | 5.13e-04 | 10 | 119 | 2 | 18083924 |
| Pubmed | Gli1 can rescue the in vivo function of Gli2. | ISL2 GLI1 | 5.13e-04 | 10 | 119 | 2 | 11748151 |
| Pubmed | Impact of cytosine methylation on DNA binding specificities of human transcription factors. | ZNF410 ISL2 YY1 GFI1 ZNF23 KLF10 ZNF281 GLIS1 | 5.85e-04 | 544 | 119 | 8 | 28473536 |
| Pubmed | Hundreds of variants clustered in genomic loci and biological pathways affect human height. | PCSK5 ZNF652 EFEMP1 JAZF1 LTBP2 | 6.14e-04 | 198 | 119 | 5 | 20881960 |
| Pubmed | PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells. | CBLL1 MIB1 | 6.26e-04 | 11 | 119 | 2 | 32737199 |
| Pubmed | Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. | ZNF101 ZKSCAN4 ZFP2 | 6.42e-04 | 49 | 119 | 3 | 9630514 |
| Pubmed | Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers. | TNC GFI1 | 7.49e-04 | 12 | 119 | 2 | 30455179 |
| Pubmed | AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis. | ISL2 GLI1 | 7.49e-04 | 12 | 119 | 2 | 20150232 |
| Pubmed | Zinc finger protein genes in the mouse genome. | GLI1 ZFP2 | 7.49e-04 | 12 | 119 | 2 | 1797234 |
| Pubmed | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. | CBLL1 ZNF652 ZNF485 YY1 ZNF260 MGAT2 ZNF28 CTCF CYCS NFXL1 ZNF664 ZNF281 | 8.80e-04 | 1203 | 119 | 12 | 29180619 |
| Pubmed | Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. | ISL2 GLI1 | 8.83e-04 | 13 | 119 | 2 | 9636069 |
| Pubmed | Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling. | TNC GLI1 | 8.83e-04 | 13 | 119 | 2 | 34557486 |
| Pubmed | Transient Nodal Signaling in Left Precursors Coordinates Opposed Asymmetries Shaping the Heart Loop. | SEMA3C TNC | 8.83e-04 | 13 | 119 | 2 | 33171097 |
| Pubmed | A hypomorphic allele reveals an important role of inturned in mouse skeletal development. | ISL2 GLI1 | 1.03e-03 | 14 | 119 | 2 | 25774014 |
| Pubmed | Gli activity is critical at multiple stages of embryonic mammary and nipple development. | TNC GLI1 | 1.03e-03 | 14 | 119 | 2 | 24260306 |
| Pubmed | Pituitary adenylyl cyclase-activating peptide counteracts hedgehog-dependent motor neuron production in mouse embryonic stem cell cultures. | ISL2 GLI1 | 1.03e-03 | 14 | 119 | 2 | 21674568 |
| Pubmed | Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases. | IL1RN SPINK5 | 1.03e-03 | 14 | 119 | 2 | 16519819 |
| Pubmed | An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression. | SEMA3C GLI1 | 1.18e-03 | 15 | 119 | 2 | 15841179 |
| Pubmed | Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation. | GLI1 GLIS1 | 1.18e-03 | 15 | 119 | 2 | 32561646 |
| Pubmed | Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis. | ISL2 GLI1 | 1.35e-03 | 16 | 119 | 2 | 15647317 |
| Pubmed | Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon. | TNC GLI1 | 1.35e-03 | 16 | 119 | 2 | 21939397 |
| Pubmed | Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. | ISL2 GLI1 | 1.35e-03 | 16 | 119 | 2 | 17026983 |
| Pubmed | Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse. | ISL2 GLI1 | 1.35e-03 | 16 | 119 | 2 | 28800946 |
| Pubmed | Dyskeratosis Congenita and Related Telomere Biology Disorders | ZCCHC8 STN1 | 1.35e-03 | 16 | 119 | 2 | 20301779 |
| Pubmed | RAB23 regulates musculoskeletal development and patterning. | TNC GLI1 | 1.35e-03 | 16 | 119 | 2 | 36910145 |
| Pubmed | Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo. | ISL2 GLI1 | 1.35e-03 | 16 | 119 | 2 | 17638910 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | PCSK5 FRAS1 FBXL19 ZNF865 NSD3 PIKFYVE KLF10 CELSR3 GLI1 TOP3B ZNF614 | 1.47e-03 | 1105 | 119 | 11 | 35748872 |
| Pubmed | SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. | TNC PLAU | 1.53e-03 | 17 | 119 | 2 | 18667463 |
| Pubmed | Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos. | GFI1 GLI1 | 1.53e-03 | 17 | 119 | 2 | 18330926 |
| Pubmed | Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. | PCSK5 SEMA3C TNC EFEMP1 LTBP2 | 1.67e-03 | 248 | 119 | 5 | 24006456 |
| Pubmed | Keratan Sulfate Regulates the Switch from Motor Neuron to Oligodendrocyte Generation During Development of the Mouse Spinal Cord. | ISL2 GLI1 | 1.71e-03 | 18 | 119 | 2 | 26869039 |
| Pubmed | PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth. | FBXL19 KDM2B | 1.71e-03 | 18 | 119 | 2 | 28614300 |
| Pubmed | Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation. | SEMA3C ISL2 | 1.71e-03 | 18 | 119 | 2 | 32105214 |
| Interaction | LTBP2 interactions | ZNF57 ZNF101 ZNF865 ZNF251 STN1 ZNF260 ZNF77 ZNF483 LTBP2 ZNF664 ZNF709 | 1.58e-12 | 85 | 113 | 11 | int:LTBP2 |
| Interaction | ZFP37 interactions | ZNF652 HINFP CTCFL CTCF GLI1 ZNF281 GLIS1 | 1.02e-08 | 49 | 113 | 7 | int:ZFP37 |
| Interaction | ZNF667 interactions | ZNF652 HINFP CTCFL CTCF GLI1 ZNF281 GLIS1 | 1.80e-08 | 53 | 113 | 7 | int:ZNF667 |
| Interaction | TRIM28 interactions | CBLL1 ZNF311 ZCCHC8 ZNF674 ZNF485 ZNF621 ZNF57 ZNF101 ZNF302 ZNF441 ZNF829 ZNF77 ZNF563 ZNF675 ZNF28 ZNF550 ZNF41 ZNF257 CYCS ZNF483 ZNF432 ZNF799 ZNF84 ZNF615 ZNF418 TOP3B ZNF614 | 3.07e-08 | 1474 | 113 | 27 | int:TRIM28 |
| Interaction | ZSCAN21 interactions | FRAS1 ZNF652 ZKSCAN5 CTCFL EFEMP1 CTCF ZNF483 LTBP2 ZKSCAN4 | 4.34e-08 | 128 | 113 | 9 | int:ZSCAN21 |
| Interaction | ZNF287 interactions | ZNF652 HINFP CTCFL CTCF GLI1 ZNF281 GLIS1 | 4.37e-08 | 60 | 113 | 7 | int:ZNF287 |
| Interaction | KAZALD1 interactions | ZNF101 ZNF865 ZNF709 TOP3B | 6.44e-07 | 13 | 113 | 4 | int:KAZALD1 |
| Interaction | ZNF710 interactions | ZNF652 HINFP CTCFL CTCF GLI1 | 6.46e-07 | 30 | 113 | 5 | int:ZNF710 |
| Interaction | KRTAP10-7 interactions | PCSK5 ZNF266 ZNF337 ZNF101 SMCP ZNF786 ZNF260 ZNF41 ZNF425 ZNF418 ZNF572 | 7.95e-07 | 293 | 113 | 11 | int:KRTAP10-7 |
| Interaction | ZNF652 interactions | ZNF652 CTCFL CTCF ZNF281 GLIS1 | 1.44e-06 | 35 | 113 | 5 | int:ZNF652 |
| Interaction | FBLN2 interactions | ZNF101 ZNF865 ZNF77 EFEMP1 ZNF664 ZNF709 | 1.88e-06 | 66 | 113 | 6 | int:FBLN2 |
| Interaction | ZFP28 interactions | ZNF652 HINFP CTCFL ZNF281 GLIS1 | 1.92e-06 | 37 | 113 | 5 | int:ZFP28 |
| Interaction | ZNF423 interactions | MAP4K3 ZNF652 CTCFL CTCF GLI1 ZNF281 | 3.41e-06 | 73 | 113 | 6 | int:ZNF423 |
| Interaction | MDFI interactions | PCSK5 ZNF266 ZNF101 YY1 TBC1D3B ZNF786 ZNF441 ZNF23 ZNF221 TBC1D3G TOP3B ZNF572 | 5.40e-06 | 430 | 113 | 12 | int:MDFI |
| Interaction | PRDM5 interactions | ZNF652 GFI1 HINFP CTCF GLI1 GLIS1 | 5.83e-06 | 80 | 113 | 6 | int:PRDM5 |
| Interaction | ZFP62 interactions | ZNF652 ZBTB47 CTCFL CTCF GLI1 GLIS1 | 1.99e-05 | 99 | 113 | 6 | int:ZFP62 |
| Interaction | ZNF697 interactions | ZNF652 CTCF ZNF281 GLIS1 | 3.38e-05 | 33 | 113 | 4 | int:ZNF697 |
| Interaction | ZNF628 interactions | EFEMP1 LTBP2 TOP3B | 9.11e-05 | 16 | 113 | 3 | int:ZNF628 |
| Interaction | RBAK interactions | ZNF652 CTCFL ZNF550 CTCF LTBP2 | 9.25e-05 | 81 | 113 | 5 | int:RBAK |
| Interaction | ZNF57 interactions | ZNF57 LTBP2 ZNF572 | 1.10e-04 | 17 | 113 | 3 | int:ZNF57 |
| Interaction | ZNF232 interactions | YY1 ZKSCAN5 ZNF483 ZKSCAN4 | 2.06e-04 | 52 | 113 | 4 | int:ZNF232 |
| Interaction | PRDM4 interactions | CTCFL CTCF ZNF281 GLIS1 | 2.06e-04 | 52 | 113 | 4 | int:PRDM4 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr17q12 | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 2.26e-13 | 149 | 119 | 11 | chr17q12 |
| Cytoband | 19q13.41 | ZNF577 ZNF880 ZNF28 ZNF432 ZNF615 ZNF614 | 5.89e-08 | 78 | 119 | 6 | 19q13.41 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19q13 | PINLYP ZNF577 ZNF880 ZNF302 ZNF865 ZNF829 ZNF404 ZNF260 ZNF28 ZNF550 ZNF432 ZNF221 ZNF615 ZNF418 ZNF614 | 5.02e-07 | 1192 | 119 | 15 | chr19q13 |
| Cytoband | 17q12 | TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F | 6.33e-06 | 99 | 119 | 5 | 17q12 |
| Cytoband | 19p13.2 | ZNF266 ZNF560 ZNF441 ZNF563 ZNF799 ZNF709 | 3.13e-05 | 229 | 119 | 6 | 19p13.2 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19p13 | ZNF266 ZNF560 ZNF57 ZNF101 ZNF441 ZNF77 ZNF563 ZNF799 ZNF709 | 2.42e-04 | 797 | 119 | 9 | chr19p13 |
| Cytoband | 12q24.31 | ZCCHC8 KDM2B ZNF664 | 1.21e-03 | 80 | 119 | 3 | 12q24.31 |
| Cytoband | 1p22 | DPYD GFI1 | 1.23e-03 | 20 | 119 | 2 | 1p22 |
| Cytoband | 16q22.2 | ZNF23 HYDIN | 1.49e-03 | 22 | 119 | 2 | 16q22.2 |
| Cytoband | 19q13.31 | PINLYP ZNF404 | 2.58e-03 | 29 | 119 | 2 | 19q13.31 |
| Cytoband | 3p22.1 | ZBTB47 ZNF621 | 4.87e-03 | 40 | 119 | 2 | 3p22.1 |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | ZNF410 ZNF311 ZNF577 ZNF266 ZNF560 ZNF337 ZNF652 ZNF674 ZNF485 ZBTB47 ZNF880 ZNF621 ZNF57 ZNF101 ZNF302 ZNF519 ZNF865 YY1 ZNF251 ZKSCAN5 GFI1 ZNF786 ZNF441 ZNF829 ZNF404 ZNF260 ZNF77 ZNF563 ZNF675 HINFP BNC1 ZNF630 CTCFL ZNF23 ZNF28 GTF3A ZNF550 KLF10 CTCF ZNF41 ZNF257 ZNF425 GLI1 ZNF483 ZNF432 JAZF1 ZNF799 ZNF84 ZNF221 ZNF615 ZNF782 ZKSCAN4 ZNF664 ZNF418 ZNF281 ZNF709 ZFP2 ZNF614 GLIS1 ZNF639 ZNF572 | 2.03e-62 | 718 | 94 | 61 | 28 |
| GeneFamily | Zinc fingers CXXC-type | FBXL19 KDM2B | 1.71e-03 | 12 | 94 | 2 | 136 |
| Coexpression | GSE2706_UNSTIM_VS_2H_LPS_DC_UP | ZNF302 ZNF260 ESCO2 HINFP ZNF23 IQCF3 ZNF432 ZNF615 ZKSCAN4 ZNF281 | 2.03e-08 | 197 | 117 | 10 | M4695 |
| CoexpressionAtlas | Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 1.32e-09 | 90 | 114 | 9 | PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05 |
| CoexpressionAtlas | DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F SPINK5 | 7.70e-08 | 242 | 114 | 11 | PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05 |
| CoexpressionAtlas | Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 2.29e-07 | 213 | 114 | 10 | PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 2.29e-07 | 213 | 114 | 10 | PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 2.85e-06 | 281 | 114 | 10 | PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 2.85e-06 | 281 | 114 | 10 | PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 5.81e-05 | 320 | 114 | 9 | PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05 |
| CoexpressionAtlas | Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 | SEMA3C TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TSPAN5 WNT5B EFEMP1 PLAU LTBP2 TBC1D3G TOP3B TBC1D3K TBC1D3F | 2.01e-04 | 1075 | 114 | 16 | PCBC_ratio_ECTO_vs_DE_cfr-2X-p05 |
| ToppCell | systemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex | ZNF577 MAP4K3 ZNF485 GFI1 ZNF441 ZNF28 ZNF257 | 5.40e-07 | 179 | 119 | 7 | 5be883d7d0be3180bb9844e4a757f0dd247294e4 |
| Disease | allergic conjunctivitis (is_implicated_in) | TNC IL1RN | 7.49e-05 | 4 | 105 | 2 | DOID:11204 (is_implicated_in) |
| Disease | response to bronchodilator, response to corticosteroid | ZNF432 ZNF614 | 1.25e-04 | 5 | 105 | 2 | GO_0031960, GO_0097366 |
| Disease | response to platinum based chemotherapy, cytotoxicity measurement | FRAS1 EYS | 1.25e-04 | 5 | 105 | 2 | EFO_0004647, EFO_0006952 |
| Disease | end stage renal disease (is_implicated_in) | DRD2 PLAU IL1RN | 4.23e-04 | 41 | 105 | 3 | DOID:783 (is_implicated_in) |
| Disease | Delirium | DRD2 IL1RN | 5.54e-04 | 10 | 105 | 2 | C0011206 |
| Disease | Brain Ischemia | CYCS PLAU IL1RN | 1.29e-03 | 60 | 105 | 3 | C0007786 |
| Disease | Cerebral Ischemia | CYCS PLAU IL1RN | 1.29e-03 | 60 | 105 | 3 | C0917798 |
| Disease | macrophage inflammatory protein 1b measurement | TBC1D3 TBC1D3B TOP3B TBC1D3F | 1.44e-03 | 136 | 105 | 4 | EFO_0008219 |
| Disease | pulmonary fibrosis (is_implicated_in) | PLAU IL1RN | 1.46e-03 | 16 | 105 | 2 | DOID:3770 (is_implicated_in) |
| Disease | depressive disorder (is_implicated_in) | DRD2 IL1RN | 1.65e-03 | 17 | 105 | 2 | DOID:1596 (is_implicated_in) |
| Disease | Usual Interstitial Pneumonia | STN1 PLAU | 2.06e-03 | 19 | 105 | 2 | C4721509 |
| Disease | Hamman-Rich Disease | STN1 PLAU | 2.06e-03 | 19 | 105 | 2 | C4721508 |
| Disease | CCL4 measurement | TBC1D3 TBC1D3F | 2.29e-03 | 20 | 105 | 2 | EFO_0004751 |
| Disease | selenium measurement, response to dietary selenium supplementation | ZC3H7A JAZF1 | 2.29e-03 | 20 | 105 | 2 | EFO_0006331, EFO_0600021 |
| Disease | Familial Idiopathic Pulmonary Fibrosis | STN1 PLAU | 2.29e-03 | 20 | 105 | 2 | C4721952 |
| Disease | Idiopathic Pulmonary Fibrosis | STN1 PLAU | 2.52e-03 | 21 | 105 | 2 | C1800706 |
| Disease | Asthma | TNC PLAU IL1RN | 2.95e-03 | 80 | 105 | 3 | C0004096 |
| Disease | autism spectrum disorder symptom | SEMA3C DCLK2 | 3.02e-03 | 23 | 105 | 2 | EFO_0005426 |
| Disease | suicidal ideation, suicide behaviour | DRD2 FBXL19 | 3.29e-03 | 24 | 105 | 2 | EFO_0004320, EFO_0007623 |
