Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	mRNA processing	RBM5 SRRT PRPF38B PRPF40B ZC3H13 DHX38 RBM17	1.12e-05	551	30	7	GO:0006397
GeneOntologyBiologicalProcess	mRNA metabolic process	RBM5 SRRT GIGYF2 PRPF38B PRPF40B ZC3H13 DHX38 RBM17	3.62e-05	917	30	8	GO:0016071
GeneOntologyBiologicalProcess	RNA splicing	RBM5 PRPF38B PRPF40B ZC3H13 DHX38 RBM17	7.29e-05	502	30	6	GO:0008380
GeneOntologyCellularComponent	spliceosomal complex	RBM5 PRPF38B PRPF40B DHX38 RBM17	1.50e-05	215	31	5	GO:0005681
HumanPheno	Abnormal lower motor neuron morphology	SPG7 MATR3 VCP	1.90e-05	26	11	3	HP:0002366
HumanPheno	Impairment in personality functioning	TNIK GIGYF2 SPG7 PTCH1 SPEN USH1G MUTYH MATR3 VCP	4.87e-05	1141	11	9	HP:0031466
HumanPheno	Abnormal volitional state	TNIK GIGYF2 SPG7 PTCH1 SPEN USH1G MUTYH MATR3 VCP	1.15e-04	1263	11	9	HP:0025780
HumanPheno	Abnormal motivation	TNIK GIGYF2 SPG7 PTCH1 SPEN USH1G MUTYH MATR3 VCP	1.15e-04	1263	11	9	HP:5200275
HumanPheno	Recurrent maladaptive behavior	TNIK GIGYF2 SPG7 PTCH1 SPEN USH1G MUTYH MATR3 VCP	1.41e-04	1293	11	9	HP:5200241
HumanPheno	Depression	GIGYF2 PTCH1 USH1G MUTYH MATR3 VCP	1.41e-04	448	11	6	HP:0000716
HumanPheno	Hallucinations	GIGYF2 USH1G MUTYH VCP	2.60e-04	160	11	4	HP:0000738
HumanPheno	Abnormal nasal skeleton morphology	PTCH1 USH1G	2.77e-04	12	11	2	HP:0010937
HumanPheno	Intestinal polyp	ERBB3 PTCH1 MUTYH	3.33e-04	67	11	3	HP:0005266
HumanPheno	Abnormal fear-induced behavior	TNIK PTCH1 USH1G MUTYH MATR3 VCP	3.92e-04	538	11	6	HP:0100852
HumanPheno	Neoplasm of the central nervous system	PTCH1 SPEN MUTYH VCP	3.92e-04	178	11	4	HP:0100006
HumanPheno	Abnormal response to social norms	TNIK GIGYF2 SPG7 PTCH1 SPEN MUTYH VCP	4.48e-04	807	11	7	HP:5200123
HumanPheno	Social disinhibition	TNIK GIGYF2 SPG7 PTCH1 SPEN MUTYH VCP	4.48e-04	807	11	7	HP:5200029
HumanPheno	Disinhibition	TNIK GIGYF2 SPG7 PTCH1 SPEN MUTYH VCP	4.48e-04	807	11	7	HP:0000734
HumanPheno	Inappropriate behavior	TNIK GIGYF2 SPG7 PTCH1 SPEN MUTYH VCP	4.48e-04	807	11	7	HP:0000719
HumanPheno	Cerebral cortical atrophy	GIGYF2 SPG7 SPEN USH1G VCP	4.61e-04	346	11	5	HP:0002120
HumanPheno	Dysphagia	GIGYF2 SPG7 PTCH1 SPEN MATR3 VCP	5.23e-04	567	11	6	HP:0002015
HumanPheno	Neoplasm of the nervous system	PTCH1 SPEN MUTYH VCP	5.56e-04	195	11	4	HP:0004375
HumanPheno	Bifid ribs	PTCH1 SPEN	5.67e-04	17	11	2	HP:0000892
Domain	Nucleotide-bd_a/b_plait	RBM5 SRRT SPEN MATR3 RBM17	6.13e-05	258	31	5	IPR012677
Domain	RRM_dom	RBM5 SPEN MATR3 RBM17	5.17e-04	227	31	4	IPR000504
Domain	RRM	RBM5 SPEN MATR3 RBM17	5.43e-04	230	31	4	PS50102
Domain	G_patch	RBM5 RBM17	6.60e-04	23	31	2	SM00443
Domain	G_patch_dom	RBM5 RBM17	6.60e-04	23	31	2	IPR000467
Domain	G-patch	RBM5 RBM17	6.60e-04	23	31	2	PF01585
Domain	G_PATCH	RBM5 RBM17	6.60e-04	23	31	2	PS50174
Domain	-	RBM5 SPEN MATR3 RBM17	6.78e-04	244	31	4	3.30.70.330
Domain	AAA	SPG7 VCP	3.36e-03	52	31	2	PF00004
Domain	ATPase_AAA_core	SPG7 VCP	3.62e-03	54	31	2	IPR003959
Domain	RRM_1	RBM5 SPEN RBM17	4.86e-03	208	31	3	PF00076
Domain	RRM	RBM5 SPEN MATR3	5.47e-03	217	31	3	SM00360
Pathway	KEGG_SPLICEOSOME	PRPF38B PRPF40B DHX38 RBM17	4.87e-05	127	23	4	M2044
Pathway	WP_MRNA_PROCESSING	RBM5 SPEN PRPF40B MATR3 DHX38 RBM17	6.59e-05	451	23	6	MM15946
Pathway	REACTOME_MRNA_SPLICING	RBM5 SRRT DHX38 RBM17	2.87e-04	201	23	4	MM15411
Pathway	REACTOME_MRNA_SPLICING	RBM5 SRRT DHX38 RBM17	3.52e-04	212	23	4	M14033
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RBM5 SRRT GIGYF2 SPEN ZC3H13 MATR3 VCP DHX38 YLPM1	2.38e-08	807	31	9	22681889
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PRPF38B ERBB3 SPEN ZC3H13 MATR3 PDCL3 PHLDB2	2.60e-08	361	31	7	26167880
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	RBM5 SRRT SPEN ZC3H13 MATR3 DHX38 YLPM1 RBM17	4.44e-08	605	31	8	28977666
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM5 SRRT PRPF38B SPEN ZC3H13 MATR3 VCP YLPM1 RBM17	2.87e-07	1082	31	9	38697112
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SRRT GIGYF2 PRPF38B SPEN ZC3H13 MATR3 PHLDB2 YLPM1	2.91e-07	774	31	8	15302935
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	RBM5 SRRT GIGYF2 ZC3H13 MATR3 VCP RBM17	4.56e-07	551	31	7	34728620
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SRRT KDM2A SPEN DHX38 YLPM1 RBM17	5.09e-07	341	31	6	32971831
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RBM5 GIGYF2 ZC3H13 MATR3 VCP DHX38 TSPYL2 RBM17	5.75e-07	847	31	8	35850772
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	RBM5 SRRT MATR3 DHX38 RBM17	8.35e-07	197	31	5	22365833
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TNIK GIGYF2 PRPF38B MATR3 VCP DHX38 YLPM1 RBM17	1.20e-06	934	31	8	33916271
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	SRRT PRPF38B ERBB3 SPEN MUTYH RBM17	1.21e-06	396	31	6	26687479
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RBM5 SRRT KDM2A SPEN ZC3H13 MATR3 DHX38 YLPM1 RBM17	1.28e-06	1294	31	9	30804502
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK GIGYF2 SPEN ADCY2 SPHKAP SEL1L3	1.42e-06	407	31	6	12693553
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SRRT PRPF38B KDM2A MATR3 VCP DHX38 YLPM1 RBM17	2.21e-06	1014	31	8	32416067
Pubmed	Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress.	GIGYF2 VCP	2.31e-06	3	31	2	36288698
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SRRT GIGYF2 SPEN MATR3 PHLDB2 VCP YLPM1 RBM17	2.37e-06	1024	31	8	24711643
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	RBM5 PRPF38B SPEN ZC3H13 RBM17	2.74e-06	251	31	5	31076518
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	SRRT PRPF38B SPG7 SPEN ZC3H13 MATR3 RBM17	2.98e-06	731	31	7	29298432
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	RBM5 SRRT GIGYF2 MATR3 VCP	4.20e-06	274	31	5	34244482
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	RBM5 SRRT SPG7 SPEN RBM17	4.92e-06	283	31	5	18854154
Pubmed	Shh/Ptch and EGF/ErbB cooperatively regulate branching morphogenesis of fetal mouse submandibular glands.	ERBB3 PTCH1	7.68e-06	5	31	2	26930157
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	SRRT GIGYF2 VCP YLPM1	8.82e-06	147	31	4	28977470
Pubmed	Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.	SRRT ZC3H13 DHX38	1.01e-05	47	31	3	15009096
Pubmed	Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.	SRRT GIGYF2 MATR3 VCP	1.06e-05	154	31	4	36490346
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SRRT ZC3H13 DHX38 RBM17	1.33e-05	163	31	4	22113938
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SRRT GIGYF2 SPEN ZC3H13 MATR3 YLPM1 RBM17	1.69e-05	954	31	7	36373674
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TNIK RBM5 SRRT PRPF38B MATR3 VCP YLPM1 RBM17	2.00e-05	1371	31	8	36244648
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	SRRT MATR3 VCP DHX38 YLPM1 RBM17	2.11e-05	653	31	6	33742100
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GIGYF2 SPEN ZC3H13 VCP DHX38 YLPM1	2.11e-05	653	31	6	22586326
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RBM5 SRRT KDM2A MATR3 VCP DHX38 YLPM1	2.13e-05	989	31	7	36424410
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	SRRT KDM2A MATR3 PHLDB2 VCP YLPM1	2.24e-05	660	31	6	32780723
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	GIGYF2 ZC3H13 PHLDB2 VCP	2.42e-05	190	31	4	15161933
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	SRRT ZC3H13 MATR3 YLPM1 RBM17	2.58e-05	399	31	5	35987950
Pubmed	Altered neural cell fates and medulloblastoma in mouse patched mutants.	ERBB3 PTCH1	2.76e-05	9	31	2	9262482
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	SRRT GIGYF2 MATR3 YLPM1	3.07e-05	202	31	4	24639526
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	TNIK GIGYF2 ERBB3 SPEN DHX38	3.29e-05	420	31	5	28065597
Pubmed	A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.	MATR3 DHX38	4.21e-05	11	31	2	25849387
Pubmed	Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.	SRRT GIGYF2 MATR3 VCP	4.52e-05	223	31	4	20020773
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	SRRT MATR3 VCP RBM17	6.41e-05	244	31	4	29884807
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SPEN MATR3 DHX38 YLPM1	1.14e-04	283	31	4	30585729
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	GIGYF2 KDM2A SPEN MATR3 YLPM1	1.16e-04	549	31	5	38280479
Pubmed	Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling.	GIGYF2 SPEN	1.17e-04	18	31	2	19640993
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	GIGYF2 SPEN	1.17e-04	18	31	2	25363768
Pubmed	The ciliary protein Ftm is required for ventricular wall and septal development.	ERBB3 PTCH1	1.30e-04	19	31	2	23469020
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	RBM5 GIGYF2 PRPF38B KDM2A MATR3 DHX38 YLPM1	1.36e-04	1327	31	7	32694731
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	SRRT GIGYF2 ZC3H13 MATR3 VCP YLPM1	1.43e-04	922	31	6	27609421
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	SRRT SPEN MATR3	1.44e-04	114	31	3	31553912
Pubmed	Recruitment of the human TREX complex to mRNA during splicing.	SRRT ZC3H13	1.45e-04	20	31	2	15998806
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	RBM5 SRRT RBM17	1.48e-04	115	31	3	17332742
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK GIGYF2 SPHKAP MATR3 PHLDB2 YLPM1	1.81e-04	963	31	6	28671696
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	GIGYF2 HOOK2 MATR3 PHLDB2 VCP	2.36e-04	639	31	5	23443559
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	SRRT GIGYF2 MATR3 VCP YLPM1	2.39e-04	641	31	5	36057605
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SRRT GIGYF2 ERBB3 HOOK2 DHX38	2.55e-04	650	31	5	38777146
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RBM5 PRPF38B KDM2A HOOK2 TCHP TSPYL2 SEL1L3	2.77e-04	1489	31	7	28611215
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRRT ZC3H13 VCP RBM17	2.88e-04	361	31	4	30344098
Pubmed	Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.	TNIK MATR3 DHX38	3.63e-04	156	31	3	29961565
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	SRRT PRPF38B ZC3H13 MATR3 RBM17	3.90e-04	713	31	5	29802200
Pubmed	Amyotrophic Lateral Sclerosis Overview	MATR3 VCP	3.99e-04	33	31	2	20301623
Pubmed	A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.	SRRT MATR3 YLPM1	4.05e-04	162	31	3	31363146
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	GIGYF2 KDM2A SPEN YLPM1 RBM17	4.18e-04	724	31	5	36232890
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SPEN VCP YLPM1 RBM17	4.65e-04	410	31	4	26949251
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	MATR3 PDCL3 VCP DHX38 YLPM1 RBM17	4.78e-04	1155	31	6	20360068
Pubmed	Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.	PRPF38B KDM2A VCP	5.07e-04	175	31	3	37866880
Pubmed	Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.	PRPF38B KDM2A	5.30e-04	38	31	2	23537643
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PTCH1 SPEN YLPM1 TSPYL2	5.57e-04	430	31	4	35044719
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	GIGYF2 SPEN PHLDB2	5.87e-04	184	31	3	32908313
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SRRT DHX38 YLPM1 TSPYL2	6.07e-04	440	31	4	34244565
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	RBM5 SRRT VCP DHX38	6.76e-04	453	31	4	29656893
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	SPEN MATR3 RBM17	6.95e-04	195	31	3	19454010
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SRRT PRPF38B MATR3 PHLDB2 VCP RBM17	7.16e-04	1247	31	6	27684187
Pubmed	The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence.	MATR3 VCP	7.43e-04	45	31	2	27512140
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SRRT SPEN ZC3H13 MATR3 PHLDB2 DHX38	7.46e-04	1257	31	6	36526897
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	GIGYF2 MATR3 RBM17	7.81e-04	203	31	3	22083510
Pubmed	Activin A Determines Steroid Levels and Composition in the Fetal Testis.	ERBB3 SEL1L3	8.11e-04	47	31	2	32274496
Interaction	MEN1 interactions	RBM5 SRRT GIGYF2 KDM2A SPEN ZC3H13 MATR3 VCP DHX38 YLPM1 RBM17	1.92e-07	1029	31	11	int:MEN1
Interaction	SNRNP40 interactions	RBM5 SRRT KDM2A SPEN PRPF40B ZC3H13 VCP DHX38 RBM17	3.22e-07	637	31	9	int:SNRNP40
Interaction	DHX8 interactions	RBM5 SPEN ZC3H13 DHX38 YLPM1 RBM17	4.77e-06	292	31	6	int:DHX8
Interaction	SAP18 interactions	SRRT PRPF38B ERBB3 ZC3H13 MATR3 VCP	6.12e-06	305	31	6	int:SAP18
Interaction	PRMT1 interactions	RBM5 SRRT GIGYF2 PTCH1 ZC3H13 MATR3 VCP YLPM1 RBM17	7.28e-06	929	31	9	int:PRMT1
Interaction	SRPK2 interactions	SRRT PRPF38B ERBB3 SPEN ZC3H13 MATR3 PDCL3 RBM17	9.42e-06	717	31	8	int:SRPK2
Interaction	MECP2 interactions	RBM5 SRRT PRPF38B SPEN PRPF40B ZC3H13 MATR3 VCP YLPM1 RBM17	1.40e-05	1287	31	10	int:MECP2
Interaction	ANKRD50 interactions	TNIK PRPF38B ZC3H13 YLPM1	2.20e-05	108	31	4	int:ANKRD50
Interaction	HDLBP interactions	TNIK RBM5 SRRT PRPF38B MATR3 VCP YLPM1 RBM17	3.36e-05	855	31	8	int:HDLBP
Interaction	ZC3H18 interactions	SRRT PRPF38B SPG7 SPEN ZC3H13 MATR3 TSPYL2 RBM17	4.02e-05	877	31	8	int:ZC3H18
Interaction	ANAPC15 interactions	GIGYF2 PRPF38B ZC3H13 DHX38	4.28e-05	128	31	4	int:ANAPC15
Interaction	OBSL1 interactions	SRRT PRPF38B SPEN MATR3 PHLDB2 VCP YLPM1 RBM17	4.91e-05	902	31	8	int:OBSL1
Interaction	ZFP91 interactions	SRRT ZC3H13 DHX38 TSPYL2	5.74e-05	138	31	4	int:ZFP91
Interaction	RBBP5 interactions	SRRT KDM2A SPEN ZC3H13 DHX38	7.10e-05	287	31	5	int:RBBP5
Interaction	UQCR11 interactions	PRPF38B ZC3H13 YLPM1	7.33e-05	53	31	3	int:UQCR11
Interaction	NAA40 interactions	TNIK GIGYF2 PRPF38B MATR3 VCP DHX38 YLPM1 RBM17	8.69e-05	978	31	8	int:NAA40
Interaction	PPP1CC interactions	TNIK SRRT ERBB3 ZC3H13 VCP YLPM1 RBM17	1.05e-04	738	31	7	int:PPP1CC
Interaction	GLDC interactions	RBM5 SRRT GIGYF2 MATR3 VCP	1.20e-04	321	31	5	int:GLDC
Interaction	CHD3 interactions	RBM5 SRRT ZC3H13 MATR3 DHX38 YLPM1 RBM17	1.23e-04	757	31	7	int:CHD3
Interaction	TP53BP1 interactions	TNIK RBM5 SRRT KDM2A VCP DHX38	1.39e-04	533	31	6	int:TP53BP1
Interaction	BTRC interactions	RBM5 PTCH1 TCHP MATR3 PHLDB2 VCP DHX38	1.42e-04	775	31	7	int:BTRC
Interaction	SF3A3 interactions	RBM5 SPEN PRPF40B MATR3 RBM17	1.57e-04	340	31	5	int:SF3A3
Interaction	LOC102724023 interactions	SPEN MATR3	1.77e-04	13	31	2	int:LOC102724023
Interaction	AKR7L interactions	SRRT GIGYF2 DHX38	1.83e-04	72	31	3	int:AKR7L
Interaction	YAP1 interactions	GIGYF2 KDM2A PTCH1 SPEN MATR3 VCP YLPM1 TSPYL2	1.90e-04	1095	31	8	int:YAP1
Interaction	WDR77 interactions	RBM5 SRRT GIGYF2 VCP YLPM1	2.08e-04	361	31	5	int:WDR77
Interaction	COBLL1 interactions	SRRT ZC3H13 DHX38	2.15e-04	76	31	3	int:COBLL1
Interaction	SHCBP1 interactions	SRRT ZC3H13 DHX38	2.23e-04	77	31	3	int:SHCBP1
Interaction	GRIA2 interactions	TNIK PRPF38B PHLDB2 TSPYL2	2.54e-04	203	31	4	int:GRIA2
Interaction	PSENEN interactions	PRPF38B ZC3H13 DHX38	2.59e-04	81	31	3	int:PSENEN
Interaction	CDC5L interactions	TNIK RBM5 SPEN MATR3 DHX38 YLPM1 RBM17	2.60e-04	855	31	7	int:CDC5L
Interaction	PCGF1 interactions	SRRT KDM2A ERBB3 YLPM1	2.79e-04	208	31	4	int:PCGF1
Interaction	TNS3 interactions	ERBB3 VCP RBM17	3.20e-04	87	31	3	int:TNS3
Interaction	NUP43 interactions	SRRT KDM2A SPEN ZC3H13 PDCL3 TSPYL2	3.30e-04	625	31	6	int:NUP43
Interaction	SIRT6 interactions	SRRT MUTYH MATR3 DHX38 YLPM1 TSPYL2	3.38e-04	628	31	6	int:SIRT6
Interaction	CES1 interactions	SRRT VCP	3.45e-04	18	31	2	int:CES1
Interaction	EZH1 interactions	PRPF38B ZC3H13 DHX38	3.77e-04	92	31	3	int:EZH1
Interaction	U2AF2 interactions	RBM5 GIGYF2 ZC3H13 MATR3 VCP RBM17	4.10e-04	651	31	6	int:U2AF2
Interaction	LINC02910 interactions	GIGYF2 PRPF38B ZC3H13	4.14e-04	95	31	3	int:LINC02910
Interaction	CLGN interactions	ERBB3 PTCH1 VCP SEL1L3	4.43e-04	235	31	4	int:CLGN
Interaction	DCX interactions	TNIK RBM5 HOOK2	4.54e-04	98	31	3	int:DCX
Interaction	CHD4 interactions	RBM5 SRRT GIGYF2 SPEN MATR3 YLPM1 RBM17	4.56e-04	938	31	7	int:CHD4
Interaction	NF1 interactions	GIGYF2 USH1G PHLDB2 VCP	4.64e-04	238	31	4	int:NF1
Interaction	HNRNPA1 interactions	RBM5 SRRT ZC3H13 MATR3 VCP YLPM1 TSPYL2	4.77e-04	945	31	7	int:HNRNPA1
Interaction	SNRPC interactions	SRRT GIGYF2 SPEN MATR3 YLPM1	5.16e-04	440	31	5	int:SNRPC
Interaction	SUPT16H interactions	TNIK SRRT ZC3H13 VCP DHX38	5.26e-04	442	31	5	int:SUPT16H
Interaction	NUPR1 interactions	SRRT KDM2A MATR3 PHLDB2 VCP YLPM1	5.29e-04	683	31	6	int:NUPR1
Interaction	AKTIP interactions	HOOK2 MATR3 VCP	5.40e-04	104	31	3	int:AKTIP
Interaction	FBXL19 interactions	KDM2A VCP SEL1L3	5.71e-04	106	31	3	int:FBXL19
Interaction	RAD18 interactions	RBM5 PRPF38B SPEN ZC3H13 RBM17	6.12e-04	457	31	5	int:RAD18
Interaction	TCEAL7 interactions	PRPF38B ZC3H13	6.19e-04	24	31	2	int:TCEAL7
Interaction	ZNF638 interactions	GIGYF2 HOOK2 MATR3 PHLDB2	6.57e-04	261	31	4	int:ZNF638
Interaction	LGR4 interactions	SRRT GIGYF2 MATR3 YLPM1	6.66e-04	262	31	4	int:LGR4
Interaction	SMC5 interactions	SRRT GIGYF2 SPEN ZC3H13 MATR3 YLPM1 RBM17	6.69e-04	1000	31	7	int:SMC5
Interaction	MIRLET7I interactions	RBM5 MATR3 RBM17	7.06e-04	114	31	3	int:MIRLET7I
Interaction	ACTR1B interactions	KDM2A MATR3 PDCL3	7.43e-04	116	31	3	int:ACTR1B
Interaction	MIRLET7G interactions	RBM5 MATR3 RBM17	7.61e-04	117	31	3	int:MIRLET7G
Interaction	DDX23 interactions	RBM5 ZC3H13 MATR3 DHX38 RBM17	7.64e-04	480	31	5	int:DDX23
Interaction	ACTR1A interactions	TNIK MATR3 PDCL3 VCP	7.88e-04	274	31	4	int:ACTR1A
Interaction	KIF23 interactions	SRRT PRPF38B ZC3H13 MATR3 PHLDB2 DHX38 RBM17	8.01e-04	1031	31	7	int:KIF23
Interaction	HDAC4 interactions	SRRT GIGYF2 HOOK2 MATR3 PHLDB2 VCP	8.29e-04	744	31	6	int:HDAC4
Interaction	SIRT7 interactions	GIGYF2 SPEN ZC3H13 VCP DHX38 YLPM1	8.29e-04	744	31	6	int:SIRT7
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	RBM5 RBM17	2.14e-04	22	18	2	579
GeneFamily	RNA binding motif containing	RBM5 SPEN RBM17	1.15e-03	213	18	3	725
GeneFamily	AAA ATPases	SPG7 VCP	1.25e-03	53	18	2	413
Coexpression	MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP	RBM5 SPG7 PTCH1 VCP SEL1L3	1.39e-05	265	31	5	M19170
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	RBM5 SRRT PRPF38B SPG7	9.24e-06	192	31	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNIK PTCH1 PHLDB2 TSPYL2	1.02e-05	197	31	4	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate\|6m / Sample Type, Dataset, Time_group, and Cell type.	SPEN ZC3H13 MATR3 PHLDB2	1.09e-05	200	31	4	7c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERBB3 ADCY2 SEL1L3	1.88e-04	161	31	3	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	GIGYF2 KDM2A PRPF40B	2.05e-04	166	31	3	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM227A PTCH1 ADCY2	2.32e-04	173	31	3	f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPHKAP PHLDB2 SEL1L3	2.32e-04	173	31	3	b002b22f9968b5967d29fe0eab4e796d87b355fa
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIGYF2 SPHKAP SEL1L3	2.40e-04	175	31	3	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM227A PTCH1 ADCY2	2.48e-04	177	31	3	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	KDM2A PTCH1 ZC3H13	2.52e-04	178	31	3	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	LV\|World / Chamber and Cluster_Paper	TNIK HOOK2 SPHKAP	2.61e-04	180	31	3	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK USH1G PHLDB2	2.74e-04	183	31	3	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK USH1G PHLDB2	2.74e-04	183	31	3	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK ADCY2 SEL1L3	2.87e-04	186	31	3	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TNIK GIGYF2 ZC3H13	2.87e-04	186	31	3	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TNIK MATR3 TSPYL2	2.92e-04	187	31	3	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	TNIK HOOK2 SPHKAP	2.92e-04	187	31	3	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK PTCH1 TSPYL2	2.96e-04	188	31	3	f8e6247bedc0ba494c5bb551539cb8ba5a97f557
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	TNIK HOOK2 SPHKAP	2.96e-04	188	31	3	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK PTCH1 TSPYL2	2.96e-04	188	31	3	8155bc5476fc333bedcc78c5ddcc8e4912536caa
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	TNIK HOOK2 SPHKAP	3.05e-04	190	31	3	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK PTCH1 TSPYL2	3.15e-04	192	31	3	58a7829b411b02b422ef75e2277a868969cc23e8
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	TNIK HOOK2 SPHKAP	3.15e-04	192	31	3	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK PTCH1 TSPYL2	3.15e-04	192	31	3	ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TNIK KDM2A TSPYL2	3.15e-04	192	31	3	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK MATR3 TSPYL2	3.20e-04	193	31	3	c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ADCY2 SEL1L3	3.25e-04	194	31	3	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ADCY2 SEL1L3	3.25e-04	194	31	3	6b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 HOOK2 SEL1L3	3.30e-04	195	31	3	576142b4e75457c0973051bccc4163bd624496af
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 HOOK2 SEL1L3	3.30e-04	195	31	3	8f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 USH1G SEL1L3	3.30e-04	195	31	3	b9e8f405f6d837bb39b615836d3e2df349737c0e
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 HOOK2 SEL1L3	3.30e-04	195	31	3	2a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 ADCY2 SEL1L3	3.34e-04	196	31	3	020110cd79453df9546fb20802fe38ecadd9fe74
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK MATR3 TSPYL2	3.34e-04	196	31	3	a9157809122e6fc5783a291522f103bef30943e4
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TNIK TSPYL2 SEL1L3	3.40e-04	197	31	3	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	RBM5 PRPF38B ZC3H13	3.40e-04	197	31	3	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	tumor_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lung / Location, Cell class and cell subclass	PRPF38B PDCL3 TSPYL2	3.40e-04	197	31	3	de26ca046038e34790cece24529a05d491e6f8ef
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TNIK PTCH1 TSPYL2	3.45e-04	198	31	3	a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TNIK PTCH1 TSPYL2	3.45e-04	198	31	3	a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TNIK PTCH1 TSPYL2	3.45e-04	198	31	3	76aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TNIK PTCH1 TSPYL2	3.45e-04	198	31	3	df399674345c45738d765a8354ea8d1484572c34
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK TSPYL2 SEL1L3	3.45e-04	198	31	3	a3bd099ef0e606c2da690a6fcf6f79e9360c9c9f
ToppCell	COVID-19_Mild-Lymphoid_T/NK-gd_T\|COVID-19_Mild / Disease group, lineage and cell class	TNIK PTCH1 TSPYL2	3.45e-04	198	31	3	6aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB3 SPHKAP SEL1L3	3.55e-04	200	31	3	858421b91f5207b7934b5c219752cb9322a3da31
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T\|COVID-19_Mild / Disease, condition lineage and cell class	TNIK PTCH1 TSPYL2	3.55e-04	200	31	3	6560753d3df2f87860b52052d4881aa45410f666
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNIK ACOT6 ADCY2	3.55e-04	200	31	3	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB3 SPHKAP SEL1L3	3.55e-04	200	31	3	a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNIK PTCH1 TSPYL2	3.55e-04	200	31	3	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB3 SPHKAP SEL1L3	3.55e-04	200	31	3	2131c8e7fa054b79906eaf60536da892438b09cd
Disease	Stomach Carcinoma	ERBB3 TCHP MUTYH	1.38e-06	21	31	3	C0699791
Disease	Colon Carcinoma	ERBB3 MUTYH	3.83e-05	9	31	2	C0699790
Disease	anxiety disorder, stress-related disorder	GIGYF2 ADCY2	7.00e-05	12	31	2	EFO_0006788, EFO_0010098
Disease	Benign neoplasm of stomach	ERBB3 MUTYH	1.44e-04	17	31	2	C0153943
Disease	Carcinoma in situ of stomach	ERBB3 MUTYH	1.44e-04	17	31	2	C0154060
Disease	Neoplasm of uncertain or unknown behavior of stomach	ERBB3 MUTYH	1.44e-04	17	31	2	C0496905
Disease	interleukin-2 receptor subunit alpha measurement	PRPF38B RBM17	2.22e-04	21	31	2	EFO_0010587
Disease	schizophrenia, intelligence, self reported educational attainment	GIGYF2 ERBB3 PRPF40B SPHKAP	4.55e-04	346	31	4	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	nasopharynx carcinoma (is_marker_for)	ERBB3 SPEN	9.39e-04	43	31	2	DOID:9261 (is_marker_for)
Disease	lung adenocarcinoma (is_implicated_in)	ERBB3 PTCH1	1.22e-03	49	31	2	DOID:3910 (is_implicated_in)
Disease	Nasal Cavity Polyp	GIGYF2 ERBB3	1.53e-03	55	31	2	EFO_1000391
Disease	Amyotrophic Lateral Sclerosis	MATR3 VCP	1.70e-03	58	31	2	C0002736
Disease	Skin Neoplasms	ERBB3 PTCH1	1.76e-03	59	31	2	C0037286
Disease	Malignant neoplasm of skin	ERBB3 PTCH1	1.76e-03	59	31	2	C0007114

Protein segments in the cluster

Peptide	Gene	Start	Entry
MERRYRRELAERSDT	USH1G	161	Q495M9
DPERFRREELMLYRR	FAM227A	301	F5H4B4
EDEDEEYEYMNRRRR	ERBB3	1191	P21860
RYRADARDELDLERA	ACOT6	51	Q3I5F7
RMDYEDDRLRDGERC	MATR3	216	P43243
ADLRAMEERYRRYVD	HOOK2	591	Q96ED9
EDERAIEMYRRRRLA	PDCL3	66	Q9H2J4
EREMKYRDRAAERRE	RBM5	696	P52756
MRRRRYLRDRSEEAA	ADCY2	6	Q08462
SQRLRGTMRRRYEDD	KDM2A	11	Q9Y2K7
REHMERRRRFEFDFR	GIGYF2	246	Q6Y7W6
RYMLRDIERDSRESA	SPHKAP	1196	Q2M3C7
RNRELEATRRQRMDY	SEL1L3	271	Q68CR1
LSMDLYRREDRRLDI	PTCH1	596	Q13635
RRRAEDEMDLDRRAY	MUTYH	111	Q9UIF7
EERRRRERDDQMYRE	SPG7	126	Q9UQ90
RERDDQMYRERLRTL	SPG7	131	Q9UQ90
GRDDLMDYHRRQREE	PHLDB2	421	Q86SQ0
VYDARDMRRRLRELT	SPEM1	261	Q8N4L4
MGDSDDEYDRRRRDK	SRRT	1	Q9BXP5
DEYDRRRRDKFRRER	SRRT	6	Q9BXP5
FRRERSDYDRSRERD	SRRT	16	Q9BXP5
HYEEQMRREEERRRA	TNIK	426	Q9UKE5
DEDERESMRSSRRRR	TSPYL2	176	Q9H2G4
IRDFYEMLAERREER	SPEN	606	Q96T58
EMLAERREERRASYD	SPEN	611	Q96T58
IRRDHFEEAMRFARR	VCP	731	P55072
DEDEDYERERRKRSM	RBM17	156	Q96I25
REKENERGRRRDRDY	PRPF38B	356	Q5VTL8
DRDYDRKRDRDERDR	DHX38	161	Q92620
EEARRMRRREAAFRS	PRPF40B	621	Q6NWY9
YERARREALERMKAE	TCHP	191	Q9BT92
IDYDRDRFDRERRPR	YLPM1	1726	P49750
DRRELRDSRDMRDSR	ZC3H13	466	Q5T200
RDSRDMRDSREMRDY	ZC3H13	471	Q5T200
RYELRADLEEERMRQ	TMC7	331	Q7Z402