Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H8 OR5H6 OR10T2

1.45e-05431528GO:0004984
GeneOntologyMolecularFunctionDNA translocase activity

ATRX RAD54L

6.62e-055522GO:0015616
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2L2 OR2W3 ADORA3 OR52A4P OR4C11 OR2G6 GPR182 OR5H8 OR5H6 OR10T2

8.00e-058845210GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2L2 OR2W3 ADORA3 OR52A4P OR4C11 OR2G6 GPR182 OR5H8 OR5H6 OR10T2 MUSK

6.07e-0413535211GO:0004888
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H8 OR5H6 OR10T2

1.17e-05432528GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H8 OR5H6 OR10T2

1.98e-05465528GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H8 OR5H6 OR10T2

2.68e-05485528GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H8 OR5H6 OR10T2

4.63e-05524528GO:0009593
GeneOntologyBiologicalProcessestablishment or maintenance of microtubule cytoskeleton polarity

CAMSAP3 CKAP5

6.20e-055522GO:0030951
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H8 OR5H6 OR10T2

6.26e-05547528GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H8 OR5H6 OR10T2

9.65e-05582528GO:0050906
GeneOntologyBiologicalProcessestablishment or maintenance of cytoskeleton polarity

CAMSAP3 CKAP5

2.22e-049522GO:0030952
DomainNPIP

NPIPB13 NPIPB3 NPIPB5 NPIPA2

6.11e-0814544IPR009443
DomainGPCR_Rhodpsn_7TM

OR2L2 OR2W3 ADORA3 OR52A4P OR4C11 OR2G6 GPR182 OR5H6 OR10T2

1.17e-04670549IPR017452
Domain7tm_1

OR2L2 OR2W3 ADORA3 OR52A4P OR4C11 OR2G6 GPR182 OR5H6 OR10T2

1.26e-04677549PF00001
DomainOlfact_rcpt

OR2L2 OR2W3 OR52A4P OR4C11 OR2G6 OR5H6 OR10T2

1.31e-04393547IPR000725
DomainG_PROTEIN_RECEP_F1_1

OR2L2 OR2W3 ADORA3 OR52A4P OR4C11 OR2G6 GPR182 OR5H6 OR10T2

1.38e-04685549PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2L2 OR2W3 ADORA3 OR52A4P OR4C11 OR2G6 GPR182 OR5H6 OR10T2

1.47e-04691549PS50262
DomainGPCR_Rhodpsn

OR2L2 OR2W3 ADORA3 OR52A4P OR4C11 OR2G6 GPR182 OR5H6 OR10T2

1.49e-04692549IPR000276
DomainEMI

UMODL1 SSPOP

1.09e-0317542PS51041
DomainDAPIN

NLRP14 NLRP5

1.83e-0322542PS50824
DomainPYRIN

NLRP14 NLRP5

1.83e-0322542PF02758
DomainDAPIN

NLRP14 NLRP5

1.83e-0322542IPR004020
DomainPYRIN

NLRP14 NLRP5

1.83e-0322542SM01289
DomainNACHT

NLRP14 NLRP5

2.00e-0323542PS50837
DomainNACHT_NTPase

NLRP14 NLRP5

2.00e-0323542IPR007111
Domain-

NLRP14 TNFRSF11B NLRP5

2.47e-03935431.10.533.10
DomainDEATH-like_dom

NLRP14 TNFRSF11B NLRP5

2.95e-0399543IPR011029
DomainSNF2_N

ATRX RAD54L

3.85e-0332542IPR000330
DomainSNF2_N

ATRX RAD54L

3.85e-0332542PF00176
DomainLRR_6

NLRP14 NLRP5

1.10e-0255542PF13516
Pubmed

Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange.

ATRX RAD54L

2.73e-06258210757799
Pubmed

The mouse germ-cell-specific leucine-rich repeat protein NALP14: a member of the NACHT nucleoside triphosphatase family.

NLRP14 NLRP5

8.19e-06358215590904
Pubmed

Interaction of human recombination proteins Rad51 and Rad54.

ATRX RAD54L

8.19e-0635829321665
Pubmed

Divergent origins and concerted expansion of two segmental duplications on chromosome 16.

NPIPB3 NPIPB5

8.19e-06358211948212
Pubmed

Homologous DNA pairing by human recombination factors Rad51 and Rad54.

ATRX RAD54L

8.19e-06358212205100
Pubmed

Rad54/Rad54B deficiency is associated to increased chromosome breakage in mouse spermatocytes.

ATRX RAD54L

8.19e-06358230204892
Pubmed

Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation.

ATRX RAD54L

1.64e-05458220150414
Pubmed

RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51.

ATRX RAD54L

2.72e-05558216990250
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FRY SLC38A10 SAMD9L SEPTIN9 CAMSAP3 CKAP5 SSPOP USP20

2.92e-0573658829676528
Pubmed

Mesenchymal cell TRPM7 expression is required for bone formation via the regulation of chondrogenesis.

TRPM7 TNFRSF11B

5.71e-05758236210025
Pubmed

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice.

ATRX RAD54L

7.60e-0585829607915
Pubmed

The malformed kidney: disruption of glomerular and tubular development.

FMN1 FGF7

1.49e-041158210668924
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

SLC38A10 CAMSAP3 CKAP5 EXOSC7 RAD54L

1.62e-0430758537499664
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

SEPTIN9 CAMSAP3 COPS6 ARMH3 ARHGAP21 STAT5A

1.78e-0449758636774506
Pubmed

Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms.

FGF7 MUSK

2.11e-041358220498043
Pubmed

TRF2-mediated telomere protection is dispensable in pluripotent stem cells.

CKAP5 ARMH3

2.46e-041458233239785
Pubmed

The genetics of NOD-like receptors in Crohn's disease.

NLRP14 NLRP5

2.46e-041458220403135
Pubmed

NALPs: a novel protein family involved in inflammation.

NLRP14 NLRP5

2.46e-041458212563287
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR2L2 OR2W3 OR4C11 OR5H8 OR5H6

2.60e-0434058511875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR2L2 OR2W3 OR4C11 OR5H8 OR5H6

2.60e-0434058511802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR2L2 OR2W3 OR4C11 OR5H8 OR5H6

2.71e-0434358532295537
Pubmed

The human olfactory receptor gene family.

OR2L2 OR2W3 OR4C11 OR5H8 OR5H6 OR10T2

2.81e-0454158614983052
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR2L2 OR2W3 OR4C11 OR5H8 OR5H6

2.82e-0434658514611657
Pubmed

Fgf21 regulates T-cell development in the neonatal and juvenile thymus.

FGF7 TNFRSF11B

4.11e-041858228336912
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

ATRX ORC3 SEPTIN9 CKAP5 MED12L COPS6

4.14e-0458258620467437
Pubmed

Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation.

FGF7 MUSK

4.59e-041958235340430
Pubmed

Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor.

NLRP14 NLRP5

4.59e-041958217567914
Pubmed

USP37 is a SNAI1 deubiquitinase.

COPS6 USP20

7.37e-042458231911859
Pubmed

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition.

NLRP14 NLRP5

8.00e-042558237493331
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

FRY ATRX FMN1 SEPTIN9 CAMSAP3

1.18e-0347558531040226
Pubmed

NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.

NLRP14 NLRP5

1.31e-033258238060382
Pubmed

A probabilistic classifier for olfactory receptor pseudogenes.

OR52A4P OR5H6

1.57e-033558216939646
Cytoband16p12.2

NPIPB4 NPIPB3 NPIPB5

1.44e-053758316p12.2
Cytoband16p11.2

NPIPB13 NPIPB12 NPIPB11 ZNF646

1.03e-0419158416p11.2
Cytoband3q12.1

OR5H8 OR5H6

3.24e-04215823q12.1
Cytoband1q44

OR2L2 OR2W3 OR2G6

3.75e-041105831q44
CytobandEnsembl 112 genes in cytogenetic band chr16p11

NPIPB13 NPIPB12 NPIPB11 ZNF646

4.32e-04278584chr16p11
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2L2 OR2W3 OR2G6

5.84e-04128583chr1q44
CytobandEnsembl 112 genes in cytogenetic band chr16p12

NPIPB4 NPIPB3 NPIPB5

1.37e-03172583chr16p12
CytobandEnsembl 112 genes in cytogenetic band chr3q11

OR5H8 OR5H6

2.15e-0354582chr3q11
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP14 NLRP5

1.12e-0325362994
GeneFamilyNLR family

NLRP14 NLRP5

1.12e-0325362666
GeneFamilyOlfactory receptors, family 2

OR2L2 OR2W3 OR2G6

1.46e-03113363149
Diseasecholesteryl ester 20:3 measurement

SEPTIN9 NPIPA2 MUSK

9.51e-0549533EFO_0010347
Diseasephosphatidylcholine 40:7 measurement

NPIPA2 MUSK

2.44e-0413532EFO_0021477
Diseasespine bone size

ADAMTSL3 MUSK

4.75e-0418532EFO_0004508
Diseasealpha-linolenic acid measurement

MUSK NLRP5

9.25e-0425532EFO_0007759
Diseaseage at assessment, lateral ventricle volume change measurement

TRIB2 MKLN1

1.08e-0327532EFO_0008007, EFO_0021502
DiseaseC-reactive protein measurement

ZNF536 OR4C11 ORC3 BCAT2 SSPOP ARHGAP21 MUSK USP20

1.31e-031206538EFO_0004458
Diseaselysophosphatidylcholine 20:3 measurement

NPIPA2 MUSK

2.36e-0340532EFO_0010362
Diseaseresting heart rate

MKLN1 ARHGAP21 MUSK

2.46e-03149533EFO_0004351
Diseaseglioblastoma (is_marker_for)

ATRX STAT5A

2.85e-0344532DOID:3068 (is_marker_for)
Diseasehip circumference

TRPM7 SEPTIN9 ANKEF1 ADAMTSL3

3.18e-03338534EFO_0005093

Protein segments in the cluster

PeptideGeneStartEntry
INDSIVYLHCKLRVC

UMODL1

1206

Q5DID0
ILREAYALCHCLPVL

COPS6

256

Q7L5N1
ETYLLILKACVVCHP

ADORA3

291

P0DMS8
CILPTKRHYRCALIA

ANKEF1

121

Q9NU02
DLYIRCIQVVHKLLC

ARMH3

466

Q5T2E6
TIHCYCPQLLRLEEV

CAMSAP3

241

Q9P1Y5
LHCRVLHVDYALKVC

ARRDC2

271

Q8TBH0
CFPLHYPIRISKRVC

OR2L2

126

Q8NH16
VTCPCEYLRKVINTL

NPIPB3

31

Q92617
VVCCRLTPLQTELYK

RAD54L

411

Q92698
CTLQLHKPITELCYI

FMN1

6

Q68DA7
VTCPCEYLRKVINTL

NPIPB12

31

F8W0I5
HFYCDIIPLLKISCT

OR5H8

176

P0DN80
KLLQLICYPHGIKEC

MED12L

1286

Q86YW9
DRCVAICKPLHYMVI

OR2W3

121

Q7Z3T1
IPCLLLIKCHLKLYR

OR52A4P

161

A6NMU1
VTCPCEYLRKVINTL

NPIPB5

31

A8MRT5
CLQHCPYLRKIRVDV

NLRP5

726

P59047
LIDHYCCDLQPLLKL

OR4C11

171

Q6IEV9
VTCPCEYLRKVINTL

NPIPA2

31

E9PIF3
VTCPCEYLRKVINTL

NPIPB4

31

C9JG80
NVPCIVTLCKIGYRH

EXOSC7

196

Q15024
AICHPLRYTLIINKR

OR10T2

126

Q8NGX3
QHFYCDIIPLLKISC

OR5H6

191

Q8NGV6
VTCPCEYLRKVINTL

NPIPB11

31

E5RHQ5
LILCVPHLYSCLEDR

CKAP5

1016

Q14008
IYRHPSLQVLICKNC

ATRX

186

P46100
KHSLALYPLVTCLLC

FRY

356

Q5TBA9
PTLLYRSCFHIICLV

FGF7

11

P21781
ACQVCPVHRILYKDR

BCAT2

341

O15382
LCYLICHRVLRGLHK

GJB3

206

O75712
LICFICPALIYKKIH

SLC38A10

356

Q9HBR0
LLHCYEVIPENAVCK

PRIMPOL

96

Q96LW4
VTCPCEYLRKVINTL

NPIPB13

31

A6NJU9
APDICIAYKLHLECS

ORC3

626

Q9UBD5
HIFCEVPVLIKLACV

OR2G6

176

Q5TZ20
LPEKICLLLEHLCHY

RPP40

286

O75818
PLPRVKAETYHCCLE

RTTN

626

Q86VV8
ELCHRYKCLLLVDSV

AGXT

171

P21549
DCCKRLLEQSLPYLH

TCAIM

451

Q8N3R3
CHRLVDKEPFYLRCL

SSPOP

771

A2VEC9
LKLCRPSKDYLLRHC

MKLN1

621

Q9UL63
RKYTELFCHLDPCLL

SAMD9L

1301

Q8IVG5
PKSRRHCLLLCAYVA

GPR182

251

O15218
KRIPDTRVHCCLYFI

SEPTIN9

401

Q9UHD8
IYSRKCLPHLVLSCV

SH3TC1

716

Q8TE82
CPLELVRCIRHILYN

STAT5A

101

P42229
CCLLRKLVVPEYSIH

CNIH2

61

Q6PI25
RYLEIEFCLKHRSCP

TNFRSF11B

111

O00300
HCVSCIGKYLLLEPL

TRIB2

56

Q92519
RHYCLLCSKEFLNPV

ZNF646

1556

O15015
KYCKVLRLPEILCIH

USP20

571

Q9Y2K6
RHIRILHKPYKCTLC

ZNF536

291

O15090
HTNRYIPLIVDICCK

ARHGAP21

1156

Q5T5U3
CVYIIPSSKDPHRCL

TRPM7

16

Q96QT4
CVDIRLKRVVPDHYC

ADAMTSL3

366

P82987
LCEALRHPKCYLERL

NLRP14

806

Q86W24
IPICREYCLAVKELF

MUSK

391

O15146