Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.14e-1111405GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

4.92e-1114405GO:0003964
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-25 ERVK-10

9.69e-1137406GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-25 ERVK-10

1.15e-1038406GO:0070001
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

4.95e-1021405GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.04e-0837405GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.19e-0838405GO:0034061
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

3.21e-0846405GO:0016893
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11 ANGEL1

2.84e-07136406GO:0004540
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

5.03e-0779405GO:0004521
GeneOntologyMolecularFunctionnuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11 ANGEL1

6.21e-06231406GO:0004518
GeneOntologyMolecularFunctionendonuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

7.40e-06136405GO:0004519
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.27e-05152405GO:0016779
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-8 ERVK-6 MCM2 ERVK-7 ERVK-10 ERVK-11

1.27e-05262406GO:0140097
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-8 ERVK-6 USP34 ERVK-19 ERVK-7 ERVK-25 ERVK-10

2.06e-05430407GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ERVK-8 ERVK-6 USP34 ERVK-19 ERVK-7 ERVK-25 ERVK-10 LACTB

3.86e-05654408GO:0008233
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11 ANGEL1

1.68e-04417406GO:0140098
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-8 ERVK-6 MCM2 ERVK-7 ERVK-10 ERVK-11 ANGEL1

2.62e-04645407GO:0140640
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-8 CRYBB1 ERVK-6 ERVK-19 DLGAP1 ERVK-7 ERVK-25 ERVK-10

3.28e-04891408GO:0005198
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH9 DNAH11

5.87e-0418402GO:0008569
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

CACNA1H NALCN

1.23e-0326402GO:0005248
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH9 DNAH11

1.43e-0328402GO:0051959
GeneOntologyMolecularFunctionzinc ion binding

ERVK-8 ZNF638 ERVK-6 ERVK-19 ERVK-7 ERVK-10 ERVK-11

1.77e-03891407GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-8 GLUL ZNF638 ERVK-6 ERVK-19 ERVK-7 ERVK-10 ERVK-11

2.15e-031189408GO:0046914
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH9 DNAH11

2.49e-0337402GO:0045505
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1H NALCN KCND3 CNGB3

4.80e-03343404GO:0005261
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

CACNA1H SLC8B1 NALCN

4.83e-03171403GO:0015081
GeneOntologyMolecularFunctionsodium channel activity

CACNA1H NALCN

4.87e-0352402GO:0005272
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11 ANGEL1

5.07e-03807406GO:0016788
GeneOntologyBiologicalProcessDNA integration

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

2.06e-1113385GO:0015074
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-8 ERVK-6 ERVK-7 ERVK-10 CTNNB1 ERVK-11

8.80e-0983386GO:0006278
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-8 ERVK-6 ERVK-7 ERVK-10 ERVK-11

2.61e-0848385GO:0000731
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-8 ERVK-6 MCM2 ERVK-7 ERVK-10 ERVK-11

8.33e-07178386GO:0006261
GeneOntologyBiologicalProcessDNA biosynthetic process

ERVK-8 ERVK-6 ERVK-7 ERVK-10 CTNNB1 ERVK-11

2.71e-06218386GO:0071897
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-8 ERVK-6 ERVK-19 CACNA1H

1.78e-0585384GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-8 ERVK-6 ERVK-19 CACNA1H

1.78e-0585384GO:0000768
GeneOntologyBiologicalProcessDNA replication

ERVK-8 ERVK-6 MCM2 ERVK-7 ERVK-10 ERVK-11

2.10e-05312386GO:0006260
GeneOntologyBiologicalProcesssyncytium formation

ERVK-8 ERVK-6 ERVK-19 CACNA1H

2.14e-0589384GO:0006949
GeneOntologyBiologicalProcessDNA recombination

ERVK-8 ERVK-6 MCM2 ERVK-7 ERVK-10 ERVK-11

5.28e-05368386GO:0006310
GeneOntologyBiologicalProcessDNA repair

ERVK-8 ERVK-6 MCM2 ERVK-7 ERVK-10 HUWE1 ERVK-11

1.58e-04648387GO:0006281
GeneOntologyBiologicalProcessDNA damage response

ERVK-8 ERVK-6 MCM2 ERVK-7 ERVK-10 HUWE1 ERVK-11 MTOR

2.99e-04959388GO:0006974
GeneOntologyCellularComponentintraciliary transport particle A

WDR19 CLUAP1

8.95e-058382GO:0030991
DomainIon_trans_dom

CACNA1H NALCN KCND3 CNGB3

4.70e-05114334IPR005821
DomainIon_trans

CACNA1H NALCN KCND3 CNGB3

4.70e-05114334PF00520
DomainDynein_heavy_dom-1

DNAH9 DNAH11

8.42e-058332IPR013594
DomainDHC_N1

DNAH9 DNAH11

8.42e-058332PF08385
DomainChannel_four-helix_dom

CACNA1H NALCN KCND3

1.38e-0457333IPR027359
Domain-

CACNA1H NALCN KCND3

1.38e-04573331.20.120.350
DomainATPase_dyneun-rel_AAA

DNAH9 DNAH11

2.72e-0414332IPR011704
DomainDynein_heavy_chain_D4_dom

DNAH9 DNAH11

2.72e-0414332IPR024317
DomainDynein_HC_stalk

DNAH9 DNAH11

2.72e-0414332IPR024743
DomainDynein_heavy_dom-2

DNAH9 DNAH11

2.72e-0414332IPR013602
DomainDHC_N2

DNAH9 DNAH11

2.72e-0414332PF08393
DomainMT

DNAH9 DNAH11

2.72e-0414332PF12777
DomainAAA_8

DNAH9 DNAH11

2.72e-0414332PF12780
DomainAAA_5

DNAH9 DNAH11

2.72e-0414332PF07728
DomainDHC_fam

DNAH9 DNAH11

3.13e-0415332IPR026983
DomainDynein_heavy_dom

DNAH9 DNAH11

3.13e-0415332IPR004273
DomainDynein_heavy

DNAH9 DNAH11

3.13e-0415332PF03028
DomainAAA+_ATPase

ABCC5 DNAH9 DNAH11

2.07e-03144333IPR003593
DomainAAA

ABCC5 DNAH9 DNAH11

2.07e-03144333SM00382
DomainARM-type_fold

USP34 HUWE1 CTNNB1 MTOR

2.88e-03339334IPR016024
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-25 ERVK-10 ERVK-11

1.45e-119440721542922
Pubmed

Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1.

GLUL CTNNB1 MTOR

1.41e-09340336256480
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

5.63e-09440310469592
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19 ERVK-10

5.63e-0944037983737
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19 ERVK-7

1.41e-08540312629516
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-8 ERVK-6 ERVK-19

3.08e-071240314557543
Pubmed

A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain.

GLUL AIF1 CTNNB1

6.35e-071540338942786
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-25 ERVK-10 ERVK-11

1.14e-061840318664271
Pubmed

Predictive Patterns of Glutamine Synthetase Immunohistochemical Staining in CTNNB1-mutated Hepatocellular Adenomas.

GLUL CTNNB1

1.29e-06240233560657
Pubmed

Identification of the primary ciliary proteins IFT38 and IFT144 to enhance serum-mediated YAP activation and cell proliferation.

WDR19 CLUAP1

1.29e-06240237783116
Pubmed

Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice.

CTNNB1 MTOR

1.29e-06240218768809
Pubmed

Propofol inhibits biological functions of leukaemia stem and differentiated cells through suppressing Wnt/β-catenin and Akt/mTOR.

CTNNB1 MTOR

1.29e-06240231429973
Pubmed

Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling.

CTNNB1 MTOR

1.29e-06240227052477
Pubmed

Mammalian target of rapamycin regulates expression of β-catenin in hepatocellular carcinoma.

CTNNB1 MTOR

1.29e-06240221239045
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

1.29e-0624029060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

1.29e-0624029460924
Pubmed

Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis.

GLUL AIF1 CTNNB1

1.35e-061940322398208
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-11

3.87e-0634029971820
Pubmed

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.

HUWE1 CTNNB1

3.87e-06340228137882
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

3.87e-06340210516026
Pubmed

Association of mammalian target of rapamycin with aggressive type II endometrial carcinomas and poor outcome: a potential target treatment.

CTNNB1 MTOR

3.87e-06340222955108
Pubmed

Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN.

CTNNB1 MTOR

7.73e-06440221695255
Pubmed

CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, β-Catenin, and hTERT Activities.

CTNNB1 MTOR

7.73e-06440227188501
Pubmed

Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.

GLUL CTNNB1

7.73e-06440229426940
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

7.73e-06440236140829
Pubmed

Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma.

CTNNB1 MTOR

7.73e-06440221062985
Pubmed

Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription.

CTNNB1 PITX1

1.29e-05540219995909
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

1.29e-05540211401426
Pubmed

Dual-color click beetle luciferase heteroprotein fragment complementation assays.

CTNNB1 MTOR

1.29e-05540220851351
Pubmed

Effect of adiponectin on cardiac β-catenin signaling pathway under angiotensin II infusion.

CTNNB1 MTOR

1.29e-05540224462873
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH9 DNAH11

1.29e-05540226909801
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

WDR19 DNAH9 DNAH11

1.35e-054040332317081
Pubmed

Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling.

CTNNB1 MTOR

1.93e-05640226180201
Pubmed

Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.

CTNNB1 PITX1

1.93e-05640221937598
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH9 DNAH11

1.93e-05640233347437
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19

1.93e-05640215063128
Pubmed

Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.

CTNNB1 MTOR

1.93e-05640225897075
Pubmed

Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth.

CTNNB1 MTOR

1.93e-05640222871496
Pubmed

DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95.

DLGAP1 CTNNB1

2.70e-0574029286858
Pubmed

Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.

GLUL CTNNB1

2.70e-05740230713111
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH9 DNAH11

2.70e-05740231178125
Pubmed

AP-2α is required after lens vesicle formation to maintain lens integrity.

CRYBB1 CTNNB1

3.60e-05840224753151
Pubmed

TRIP6 functions in brain ciliogenesis.

CLUAP1 CTNNB1

4.62e-05940234620853
Pubmed

Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum.

GLUL CTNNB1

4.62e-05940226974334
Pubmed

Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation.

CTNNB1 PITX1

4.62e-05940239052671
Pubmed

Alix is required during development for normal growth of the mouse brain.

AIF1 CTNNB1

4.62e-05940228322231
Pubmed

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

USP34 HUWE1

5.77e-051040217478428
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19

5.77e-051040212970426
Pubmed

A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.

CRYBB1 AIF1

5.77e-051040236791722
Pubmed

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.

GLUL CTNNB1

7.05e-051140220084116
Pubmed

Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis, and neurodegenerative diseases.

AIF1 MTOR

8.45e-051240224857653
Pubmed

Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress.

MCM2 CTNNB1

8.45e-051240235623353
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

ERVK-6 ERVK-10 PITX1

8.99e-057540315372022
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WDR19 GLUL USP34 ABCC5 WHAMM DLGAP1 DNAAF9 HUWE1

9.11e-05128540835914814
Pubmed

mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis.

CTNNB1 MTOR

9.98e-051340227993979
Pubmed

Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain.

GLUL AIF1

9.98e-051340228472653
Pubmed

Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor.

GLUL AIF1

9.98e-051340225285789
Pubmed

Brain milieu induces early microglial maturation through the BAX-Notch axis.

AIF1 CTNNB1

1.16e-041440236253375
Pubmed

PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development.

AIF1 MCM2

1.34e-041540237371026
Pubmed

N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.

CRYBB1 CTNNB1

1.34e-041540228552735
Pubmed

Identification of NeuN immunopositive cells in the adult mouse subventricular zone.

AIF1 MCM2

1.53e-041640229752725
Pubmed

Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex.

AIF1 CTNNB1

1.53e-041640225425146
Pubmed

TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.

MCM2 CTNNB1

1.53e-041640231823782
Pubmed

mTOR deletion in neural crest cells disrupts cardiac outflow tract remodeling and causes a spectrum of cardiac defects through the mTORC1 pathway.

CTNNB1 MTOR

1.73e-041740234052210
Pubmed

Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.

GLUL CTNNB1

1.73e-041740226025376
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

USP34 MCM2 DLGAP1 HUWE1

1.83e-0424640415345747
Pubmed

Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway.

CTNNB1 PITX1

1.95e-041840224424161
Pubmed

CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.

CTNNB1 MTOR

1.95e-041840233462112
Pubmed

Wnt/β-catenin promotes gastric fundus specification in mice and humans.

CTNNB1 PITX1

1.95e-041840228052057
Pubmed

Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning.

GLUL MCM2

1.95e-041840227392482
Pubmed

Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.

CTNNB1 MTOR

1.95e-041840233323119
Pubmed

Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models.

AIF1 MTOR

2.18e-041940223744272
Pubmed

Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures.

GLUL AIF1

2.18e-041940232579270
Pubmed

Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain.

GLUL AIF1

2.18e-041940236916004
Pubmed

Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function.

AIF1 MCM2

2.18e-041940230699346
Pubmed

Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development.

AIF1 MCM2

2.18e-041940235173232
Pubmed

Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts.

GLUL CTNNB1

2.42e-042040226033091
Pubmed

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling.

CTNNB1 PITX1

2.42e-042040218231602
Pubmed

Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis.

CTNNB1 MTOR

2.67e-042140223637172
Pubmed

ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.

CTNNB1 MTOR

2.67e-042140230985297
Pubmed

Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.

CTNNB1 DNAH11

2.67e-042140216291790
Pubmed

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.

GDF7 CTNNB1

2.94e-042240217150208
Pubmed

Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development.

GLUL CTNNB1

2.94e-042240229249622
Pubmed

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors.

CTNNB1 PITX1

2.94e-042240217919533
Pubmed

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

CTNNB1 MTOR

3.21e-042340222017875
Pubmed

Cd9 Protects Photoreceptors from Injury and Potentiates Edn2 Expression.

GLUL AIF1

3.21e-042340232150249
Pubmed

Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development.

AIF1 CTNNB1

3.21e-042340236103829
Pubmed

Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea.

CTNNB1 KCND3

3.21e-042340237873566
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

ZNF638 AIF1 DLGAP1 GDF7 SIGLEC7 EPX

3.35e-0482440620237496
Pubmed

DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.

AIF1 CTNNB1

3.50e-042440232553121
Pubmed

mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.

HUWE1 MTOR

3.80e-042540230340022
Pubmed

Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.

CTNNB1 MTOR

4.45e-042740228542142
Pubmed

Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions.

AIF1 MTOR

5.50e-043040222056141
Pubmed

Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma.

GLUL CTNNB1

5.87e-043140222228100
Pubmed

Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent.

GLUL CTNNB1

5.87e-043140236656901
Pubmed

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.

HUWE1 KCND3

6.66e-043340222357600
Pubmed

mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development.

CTNNB1 MTOR

6.66e-043340229975682
Pubmed

LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.

CACNA1H KCND3

7.07e-043440226378152
Pubmed

mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics.

CTNNB1 MTOR

7.07e-043440232866472
Pubmed

The transcription factor RBP-J is essential for retinal cell differentiation and lamination.

GLUL CTNNB1

7.07e-043440220017954
InteractionGLUL interactions

GLUL USP34 MCM2 DLGAP1 HUWE1 LACTB

2.55e-07160346int:GLUL
Cytoband2p24.1

LAPTM4A GDF7

1.76e-04233922p24.1
Cytoband16p13.3

CACNA1H CLUAP1 RPUSD1

1.18e-0324439316p13.3
CytobandEnsembl 112 genes in cytogenetic band chr2p24

LAPTM4A GDF7

2.18e-0381392chr2p24
GeneFamilyDyneins, axonemal

DNAH9 DNAH11

2.46e-0417252536
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

WDR19 CLUAP1

4.97e-0424252615
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NALCN DNAH9 CNGB3 DNAH11

7.22e-0616933412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

GLUL CRYBB1 AIF1 LAPTM4A

1.08e-0518733455d5b21517c89736592982af40fd4cd64be62a3c
ToppCell10x5'-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

GLUL CRYBB1 AIF1 SIGLEC7

1.15e-051903349db04555c98eca1df15d144fbb499e0ba06660d5
ToppCellmetastatic_Brain-Myeloid_cells-Undetermined|metastatic_Brain / Location, Cell class and cell subclass

GLUL CRYBB1 AIF1 SIGLEC7

1.22e-05193334e7d2833ad48e4db547d046514036948c58c01dde
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CRYBB1 AIF1 ABCC5 DNAAF9

1.27e-051953344008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ZNF638 AIF1 CLUAP1 SLC8B1

1.27e-05195334d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellSevere_COVID-19-Myeloid-MoAM4|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

GLUL ZNF638 AIF1 ABCC5

1.40e-0520033430448a41ca64d6f0fedaff0b7a6670dd33cdf2c5
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GLUL ZNF638 AIF1 ABCC5

1.40e-05200334cf720d3973e79ffd4c6e763a7284799ced22a274
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GLUL ZNF638 AIF1 ABCC5

1.40e-05200334df821ac12953e44fcfedbbefb35a4976e406ccd6
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GLUL ZNF638 AIF1 ABCC5

1.40e-052003344f481d87e30195365900acb5d50641a9e7b2f462
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GLUL ZNF638 AIF1 ABCC5

1.40e-052003345490393c5f54748f912676e19b58bd1320415a06
ToppCellMild/Remission-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WHAMM CACNA1H RERE

1.77e-04148333dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCellE16.5-samps-Myeloid-Macrophage-CD163+_Macrophage|E16.5-samps / Age Group, Lineage, Cell class and subclass

CRYBB1 AIF1 DNAH9

1.77e-0414833356e146980a71b5ca655118ae13310c5949220d4a
ToppCellE16.5-samps-Myeloid-Macrophage|E16.5-samps / Age Group, Lineage, Cell class and subclass

CRYBB1 AIF1 DNAH9

1.77e-04148333cd5f697d8c2f272be1f3f52a05446749278431c5
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

GLUL AIF1 NALCN

2.03e-0415533303fd443740272dcb547e39deaf7ae89b8307f241
ToppCellCOPD-Epithelial-PNEC|COPD / Disease state, Lineage and Cell class

CACNA1H KCND3 PITX1

2.19e-041593336018124980c55190928409f3bf41d846a118954a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

DLGAP1 DNAAF9 NALCN

2.27e-04161333347edb0de10850b7d16c40945751033289289c9b
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 PITX1 DNAH11

2.39e-04164333e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLUL AIF1 SIGLEC7

2.39e-04164333f2b4d69ee994977275db5ad6d38f681cfe827db0
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIGLEC7 EPX DNAH11

2.48e-04166333da10d0be6b616199d49dd922591c2901f9681583
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|390C / Donor, Lineage, Cell class and subclass (all cells)

CRYBB1 AIF1 MCM2

2.57e-041683332082b15fc7935a211f1c61506b305af5501a21ad
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH9 DNAH11

2.61e-0416933314aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRYBB1 AIF1 LACTB

2.71e-04171333b520d4d5620cac08315e4cbb7e796c5e9e233060
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-non-classical_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GLUL AIF1 SIGLEC7

2.75e-04172333968d18ab8c3cdeb7936a2aa721a7f41525763863
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYBB1 AIF1 EPX

2.80e-04173333b9dc42d629d13e63aada5ae49ba0cbb0952c5fe9
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

GLUL CRYBB1 AIF1

2.85e-0417433375b3a852140fb726025c3c987143d67944afde2d
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

CACNA1H NALCN KCND3

3.09e-04179333988d0853c391da1e5004f73f3678047418d3f6d3
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

WDR19 KCND3 DNAH11

3.09e-04179333140dd7dbac48f5f07279f31bf971d7fbd41fa18b
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Undetermined|normal_Pleural_Fluid / Location, Cell class and cell subclass

GLUL AIF1 SIGLEC7

3.25e-04182333bfab19f855c4a595f7d652d43f159f0fcd8d56d1
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AIF1 DNAAF9 SIGLEC7

3.25e-04182333ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H GDF7 DNAH9

3.25e-04182333398ce074a04f6482470b488f1affae4af7d2ec58
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLUL AIF1 SIGLEC7

3.30e-04183333c289a257918aa660db8657810b3c4881382d56f3
ToppCelltumor_Lung-Myeloid_cells-Undetermined|tumor_Lung / Location, Cell class and cell subclass

GLUL CRYBB1 AIF1

3.30e-041833337ef79365514e62dfc2e182e873e2b413d4f46b46
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLUL AIF1 LAPTM4A

3.35e-0418433397ae5ffecf90df42cc8eea2a247ca589f35a4783
ToppCell3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1|GI_small-bowel / Manually curated celltypes from each tissue

AIF1 GDF7 NALCN

3.35e-041843338e393eea7240584a3cef718bee094e2705ec1891
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR19 DNAH9 DNAH11

3.52e-0418733304dba2ed09ee4180830bdf0191921696697ea234
ToppCell10x5'-bone_marrow-Myeloid_Mac|bone_marrow / Manually curated celltypes from each tissue

GLUL CRYBB1 AIF1

3.52e-0418733399f39818b896032957fe123936d9e1877311c42e
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR19 DNAH9 DNAH11

3.52e-04187333805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

GLUL AIF1 SIGLEC7

3.52e-0418733388fac9f23047892acccbcc355d02ff079596fedf
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 HUWE1 CTNNB1

3.57e-04188333ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLUL CRYBB1 AIF1

3.57e-04188333cb091912f9b627a78a8793a37df7f1de839f887f
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLUL AIF1 SIGLEC7

3.57e-04188333fcf1bebef7aa81b4a11c1f9e4319339c290ecd22
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCND3 PITX1 DNAH11

3.57e-04188333879de94924de978478696fc7838e05a4d795b905
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GLUL CTNNB1 DNAH11

3.63e-0418933398f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLUL AIF1 LAPTM4A

3.63e-04189333cce6602ad68c177985a5e43cfb2776d615cfbca0
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL ABCC5 CTNNB1

3.63e-04189333287e59104687fe1665232c52993889f0f2c97f17
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYBB1 AIF1 SIGLEC7

3.63e-04189333b491204cf38dc80a2583e3082a82dda8d77b3fc4
ToppCellwk_20-22-Hematologic-Myeloid-APOE+_Mac2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GLUL AIF1 SIGLEC7

3.63e-04189333e189ef6066f87177d758f0e3ed9a17e01031a391
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLUL AIF1 LACTB

3.63e-04189333131a36e2c900b3b22ba920e0658815e8e278e87d
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCND3 PITX1 DNAH11

3.63e-04189333ab7ece0a517499b70b7754720d3e434765363af6
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL ABCC5 CTNNB1

3.63e-041893336d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GLUL CTNNB1 DNAH11

3.63e-04189333f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

ABCC5 MCM2 PITX1

3.63e-04189333aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Erythrophagocytic_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

GLUL AIF1 SIGLEC7

3.68e-0419033396c6078619e85f630c9754aca5d6066433e22836
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL HUWE1 CTNNB1

3.68e-041903331d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLUL AIF1 LACTB

3.68e-04190333e1c02fe6fa43a36381cb9f02569fa9b1c5f5efdc
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLUL AIF1 LACTB

3.68e-041903336de15ec88426fbf52acb0a8371f82cf03b6a6237
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

GLUL ABCC5 CTNNB1

3.74e-041913337bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLUL AIF1 SIGLEC7

3.74e-0419133387b974a320888d63aa8cefcd8dc97d525b56d848
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLUL AIF1 LACTB

3.74e-04191333bd0f8adfb2a508babee73477d0e9300330471e7a
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLUL AIF1 LACTB

3.74e-0419133381f77bf497b8e0ae0affe7d5f4f00446547229f6
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF638 DLGAP1 RERE

3.80e-04192333916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellURO|World / Disease, Lineage and Cell Type

GLUL AIF1 CTNNB1

3.86e-04193333421dc0996c6c973f88e90197b651255ae4dd13a2
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF638 DLGAP1 RERE

3.86e-04193333e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

CRYBB1 AIF1 SIGLEC7

3.86e-041933336e9912f5444c591e698b9a7ffa3e9fc3d8ee57b0
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Undetermined|metastatic_Lymph_Node / Location, Cell class and cell subclass

GLUL CRYBB1 AIF1

3.86e-0419333347249aabdd912052aa635d276eed20d32b525393
ToppCellCOPD-Myeloid|COPD / Disease state, Lineage and Cell class

GLUL AIF1 CTNNB1

3.86e-04193333f58552e286aa27e592497ad78776f58f8ee09841
ToppCellmyeloid-macrophage|World / Lineage and Cell class

GLUL CRYBB1 AIF1

3.86e-04193333b13e694123b87ed8ad1786feb996398ddd84e94b
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CLUAP1 DNAH9 DNAH11

3.92e-041943337a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CRYBB1 AIF1 CNGB3

3.92e-041943334f28841c7f37884fc34c6689cd6976c6559d23f1
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid-Microglia|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CRYBB1 AIF1 CNGB3

3.92e-04194333459e836bcdb6742333684ac23d960efa5e99702f
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH9 DNAH11

3.92e-041943334a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellMonocytes-Phagocytic_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

GLUL ABCC5 SIGLEC7

3.92e-0419433340dbfdf1d7e6b73d120d8f802f08e573fe9a739e
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CLUAP1 DNAH9 DNAH11

3.92e-04194333b4ce60c06568123008b1081d644733cb91c28f51
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH9 DNAH11

3.92e-04194333a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLUL AIF1 ABCC5

3.97e-04195333c16479a10f5ca2e89aea1742dbc5cc4dc9f3ea88
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH9 DNAH11

3.97e-0419533393b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH9 DNAH11

3.97e-041953330e763f36786515698b593e5c93f6a56619c1242d
ToppCell(3)_MNP-(3)_Macrophage_MARCOneg|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

CRYBB1 AIF1 ABCC5

3.97e-04195333e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

GLUL AIF1 CTNNB1

3.97e-0419533346ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLUL CRYBB1 AIF1

3.97e-04195333028622b234551b185977fbee10c06851a45456a5
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GLUL LAPTM4A EPX

3.97e-04195333f1f48e2e57b2282572959b152aad4bee05143f03
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH9 DNAH11

3.97e-041953339651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH9 DNAH11

3.97e-04195333581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLUL AIF1 SIGLEC7

3.97e-041953335a7c74f96f213c504abd65e751800da7e03e47d9
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|356C / Donor, Lineage, Cell class and subclass (all cells)

GLUL AIF1 ABCC5

3.97e-041953339231e929657542b78a6480d44402866511129c7f
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLUL AIF1 CTNNB1

3.97e-04195333ec218ae03ebf8588996e86d6d9a8ea3cf71affaa
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

CLUAP1 DNAH9 DNAH11

4.03e-04196333de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CLUAP1 DNAH9 DNAH11

4.03e-041963339a91a6e5f93ce3bb5a0fc63677553f4c2df95c43
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CRYBB1 AIF1 SIGLEC7

4.03e-041963336038c566c58a24b3582011344039e16ff0dda95f
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CRYBB1 AIF1 SIGLEC7

4.03e-0419633388517bb92be2f05c1e1ad94af22ac10d8c5c13c7
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLUL LAPTM4A EPX

4.03e-0419633303710e2a843279124a45a271bffb132835e6081c
ToppCell(7)_Macrophage|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

GLUL AIF1 SIGLEC7

4.03e-04196333f1c822860d2a0bae84b0263b0151185756423e0f
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_Resident_macrophages|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GLUL AIF1 LAPTM4A

4.09e-041973338736f1d446db3eb28a99997a9a683ded8e18e4c6
ToppCell(3)_Macrophage_MARCOneg|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

GLUL CRYBB1 AIF1

4.09e-04197333b0ee2ce1179b60b4542559acb300a34295277dbc
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLUL AIF1 SIGLEC7

4.09e-0419733361f2c420b77d0527d57532172b07bfb7a4cf971a
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLUL CRYBB1 AIF1

4.09e-0419733372775eb6c24cfb956436642ac9cd6e4d5c01ea5f
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CLUAP1 DNAH9 DNAH11

4.09e-0419733371fea4aa6ce96c7693fa94792d08770622873850
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Luminal_Macrophages|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

GLUL AIF1 LACTB

4.09e-04197333523a7f363c7ba8c196ea6e4f7544c29c18c10b51
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLUL LAPTM4A EPX

4.09e-041973335e4a004052b8560223673a339d4a0d729e533def
DrugLynestrenol [52-76-6]; Up 200; 14uM; MCF7; HT_HG-U133A

USP34 CACNA1H SLC8B1 SIGLEC7 KCND3

6.93e-061813451537_UP
DrugAconitine [302-27-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A

RERE SLC8B1 SIGLEC7 DNAH9 PITX1

9.71e-061943452776_UP
Diseasetemporal lobe epilepsy (implicated_via_orthology)

GLUL MTOR

3.83e-059312DOID:3328 (implicated_via_orthology)
DiseaseLymphoma, Lymphocytic, Intermediate

CTNNB1 MTOR

5.84e-0511312C0751958
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

CTNNB1 MTOR

1.27e-0416312C0334634
DiseaseLiver carcinoma

GLUL MCM2 CTNNB1 MTOR PITX1

1.72e-04507315C2239176
DiseaseLeft Ventricular Hypertrophy

CTNNB1 MTOR

3.16e-0425312C0149721
Diseasemigraine disorder, glucose measurement

CACNA1H RERE

4.87e-0431312EFO_0004468, MONDO_0005277
DiseaseColonic Neoplasms

MCM2 CTNNB1 MTOR

5.42e-04152313C0009375
Diseasecervical cancer

CTNNB1 MTOR

5.87e-0434312C4048328
Diseasecognitive function measurement

WDR19 ZNF638 USP34 ABCC5 CACNA1H CTNNB1 CNGB3

5.93e-041434317EFO_0008354
DiseaseMalignant tumor of colon

MCM2 CTNNB1 MTOR

6.18e-04159313C0007102
DiseaseUterine Cervical Neoplasm

CTNNB1 MTOR

6.22e-0435312C0007873

Protein segments in the cluster

PeptideGeneStartEntry
RFTYHMVSGMSLRPR

ERVK-19

191

O71037
RFTYHMVSGMSLRPR

ERVK-8

191

Q902F8
YRSDRLMSFRPIKMD

CRYBB1

131

P53674
AMRPDRMTYALRNFV

DNAH11

3886

Q96DT5
SPKFRSRNESYMRAM

DLGAP1

431

O14490
MRSMRKTFARYLSFR

MCM2

811

P49736
YAMTRAQRVRAAMFP

CTNNB1

86

P35222
MSFFFVDLRPMNRSA

OR11H4

1

Q8NGC9
FAAPSRYRFIRSVMS

KCND3

246

Q9UK17
MVSMSFKRNRSDRFY

LAPTM4A

1

Q15012
MYRLMSAVTARAAAP

LACTB

1

P83111
LFYGAAMFMYLRPRR

OR2V1

251

Q8NHB1
AMFMYLRPRRYRAPS

OR2V1

256

Q8NHB1
MLQPFMFRLDSQYRA

EPX

476

P11678
REMFNPMYALFRTSP

HUWE1

4071

Q7Z6Z7
RFTYHMVSGMSLRPR

ERVK-7

951

P63135
PAMMFASRLTAYFRR

ABCC5

331

O15440
RFTYHMVSGMSLRPR

ERVK-25

191

P61570
RFTYHMVSGMSLRPR

ERVK-6

191

Q69384
SFSSPEMLRSRYLMY

DNAAF9

941

Q5TEA3
RFTYHMVSGMSLRPR

HERVK_113

191

Q902F9
AMRPDRMTYALRDFV

DNAH9

3856

Q9NYC9
VSRMLSLPNDSYMFR

CACNA1H

1921

O95180
MAASRPFFRDIVFYM

SLC8B1

196

Q6J4K2
FYPAVSMVALMRIFR

MTOR

946

P42345
DMYLVPAAMFRDPFR

GLUL

76

P15104
DRPFRMMLHAFYLRI

RPUSD1

201

Q9UJJ7
ATFQRNRYPDMSMRE

PITX1

106

P78337
FMMSLYRSLAGRAPA

GDF7

91

Q7Z4P5
RDARMSDAGRYFFRM

SIGLEC7

111

Q9Y286
TMFFQYLLQPFRAMR

WHAMM

236

Q8TF30
FSFAAMLMRPEYRSK

WDR19

1211

Q8NEZ3
DLLMYLRAARSMAAF

RERE

326

Q9P2R6
FSYPDFLRMMLGKRS

AIF1

101

P55008
SLRMMGFTCFYKRRT

ANGEL1

311

Q9UNK9
PMFRANRMLKYTSFF

CNGB3

321

Q9NQW8
LRNFTEMMRALGYPR

CLUAP1

6

Q96AJ1
RFTYHMVSGMSLRPR

ERVK-10

951

P10266
RFTYHMVSGMSLRPR

ERVK-11

951

Q9UQG0
PRILSFNTMRYTFNM

USP34

2081

Q70CQ2
RRSRSPMHYMYRPRS

ZNF638

506

Q14966
RFTTFPRAFMSMFQI

NALCN

536

Q8IZF0