Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2 ITPR3

1.77e-083533GO:0005220
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2 ITPR3

6.30e-0614533GO:0070679
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2 ITPR3

1.40e-0518533GO:0015278
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2 ITPR3

7.53e-0531533GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3

9.11e-0533533GO:0005217
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1H ITPR1 ITPR2 ITPR3

3.81e-04129534GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1H ITPR1 ITPR2 ITPR3

6.90e-04151534GO:0015085
GeneOntologyBiologicalProcesscellular response to cAMP

PIK3CG ITPR1 ITPR2 ITPR3

8.88e-0653514GO:0071320
GeneOntologyBiologicalProcessresponse to purine-containing compound

PRSS3 PIK3CG ITPR1 ITPR2 ITPR3

5.54e-05166515GO:0014074
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2 ITPR3

1.43e-069553GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2 ITPR3

2.80e-0611553GO:0031094
GeneOntologyCellularComponentIgE immunoglobulin complex

IGLC7 IGHE

1.01e-046552GO:0071742
GeneOntologyCellularComponentspectrin-associated cytoskeleton

SPTB SPTBN1

2.42e-049552GO:0014731
GeneOntologyCellularComponentspectrin

SPTB SPTBN1

2.42e-049552GO:0008091
DomainInsP3_rcpt-bd

ITPR1 ITPR2 ITPR3

2.16e-083533IPR000493
DomainRIH_assoc

ITPR1 ITPR2 ITPR3

4.29e-076533PF08454
DomainRIH_assoc-dom

ITPR1 ITPR2 ITPR3

4.29e-076533IPR013662
DomainRIH_dom

ITPR1 ITPR2 ITPR3

4.29e-076533IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2 ITPR3

4.29e-076533IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2 ITPR3

4.29e-076533IPR015925
Domain-

ITPR1 ITPR2 ITPR3

4.29e-0765331.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2 ITPR3

4.29e-076533PF01365
DomainIns145_P3_rec

ITPR1 ITPR2 ITPR3

4.29e-076533PF08709
DomainMIR

ITPR1 ITPR2 ITPR3

2.55e-0610533PS50919
DomainMIR

ITPR1 ITPR2 ITPR3

2.55e-0610533PF02815
DomainMIR

ITPR1 ITPR2 ITPR3

2.55e-0610533SM00472
DomainMIR_motif

ITPR1 ITPR2 ITPR3

2.55e-0610533IPR016093
DomainNPIP

NPIPB15 NPIPB9 NPIPB6

7.68e-0614533IPR009443
DomainEMI_domain

EMID1 EMILIN1 MEGF11

1.18e-0516533IPR011489
DomainEMI

EMID1 EMILIN1 MEGF11

1.43e-0517533PS51041
DomainSpectrin_bsu

SPTB SPTBN1

4.72e-054532IPR016343
DomainIon_trans_dom

CACNA1H ITPR1 ITPR2 ITPR3

3.06e-04114534IPR005821
DomainIon_trans

CACNA1H ITPR1 ITPR2 ITPR3

3.06e-04114534PF00520
DomainEMI

EMID1 EMILIN1

3.50e-0410532PF07546
DomainRCC1

HERC1 HERC5

1.45e-0320532PF00415
DomainRCC1_1

HERC1 HERC5

1.60e-0321532PS00625
DomainRCC1_2

HERC1 HERC5

1.60e-0321532PS00626
DomainRCC1_3

HERC1 HERC5

1.60e-0321532PS50012
DomainReg_chr_condens

HERC1 HERC5

1.76e-0322532IPR000408
Domain-

HERC1 HERC5

1.76e-03225322.130.10.30
DomainActinin_actin-bd_CS

SPTB SPTBN1

1.92e-0323532IPR001589
DomainSpectrin

SPTB SPTBN1

1.92e-0323532PF00435
DomainACTININ_2

SPTB SPTBN1

1.92e-0323532PS00020
DomainACTININ_1

SPTB SPTBN1

1.92e-0323532PS00019
DomainRCC1/BLIP-II

HERC1 HERC5

1.92e-0323532IPR009091
DomainHECT

HERC1 HERC5

2.65e-0327532PF00632
DomainHECTc

HERC1 HERC5

2.65e-0327532SM00119
DomainHECT_dom

HERC1 HERC5

2.65e-0327532IPR000569
DomainHECT

HERC1 HERC5

2.65e-0327532PS50237
DomainARM-type_fold

TNPO1 PSME4 PIK3CG ITPR1 ITPR2

2.69e-03339535IPR016024
DomainSpectrin_repeat

SPTB SPTBN1

3.05e-0329532IPR002017
DomainSpectrin/alpha-actinin

SPTB SPTBN1

3.71e-0332532IPR018159
DomainSPEC

SPTB SPTBN1

3.71e-0332532SM00150
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.27e-075413M49000
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

4.54e-076413M47960
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

RASGRP2 ITPR1 ITPR2 ITPR3

1.03e-0627414M12123
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.90e-069413M47852
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.70e-0610413M47661
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.71e-0611413M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2 ITPR3

3.71e-0611413M27466
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

6.40e-0613413M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

6.40e-0613413M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

6.40e-0613413M47751
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

6.40e-0613413MM14553
PathwaySIG_CHEMOTAXIS

PIK3CG ITPR1 ITPR2 ITPR3

8.42e-0645414M5193
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

1.25e-0516413M26945
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

PSME4 IGHE RASGRP2 ITPR1 ITPR2 ITPR3

1.49e-05186416M27175
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2 ITPR3

2.14e-0519413M27423
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.14e-0519413M47760
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.14e-0519413M47733
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.52e-0520413M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.93e-0521413M47689
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

3.38e-0522413M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

3.38e-0522413M47675
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

3.88e-0523413M47676
PathwayKEGG_LONG_TERM_DEPRESSION

PLA2G3 ITPR1 ITPR2 ITPR3

4.91e-0570414M8232
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

5.02e-0525413MM14511
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

6.36e-0527413MM15053
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

PIK3CG ITPR1 ITPR2 ITPR3

6.79e-0576414M9052
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

7.11e-0528413M924
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

1.07e-0432413MM14983
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGHE ITPR1 ITPR2 ITPR3

1.10e-0486414M27206
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

ITPR1 ITPR2 ITPR3

1.53e-0436413M1315
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

ITPR1 ITPR2 ITPR3

1.53e-0436413M39831
PathwayREACTOME_CLEC7A_DECTIN_1_SIGNALING

PSME4 ITPR1 ITPR2 ITPR3

1.97e-04100414M27467
PathwayKEGG_GNRH_SIGNALING_PATHWAY

PLA2G3 ITPR1 ITPR2 ITPR3

2.05e-04101414M1979
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ITPR1 ITPR2 ITPR3

2.25e-0441413M512
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

2.42e-0442413M791
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

ITPR1 ITPR2 ITPR3

2.78e-0444413M39845
PathwaySIG_BCR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.18e-0446413M8626
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

PLA2G3 ITPR1 ITPR2 ITPR3

3.37e-04115414M9387
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTB SPTBN1

3.66e-0410412MM15112
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

4.07e-0450413M47951
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

ITPR1 ITPR2 ITPR3

4.84e-0453413MM15716
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ITPR1 ITPR2 ITPR3

5.11e-0454413M26911
PathwayREACTOME_ION_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

5.11e-0454413M27460
PathwayREACTOME_ION_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

5.11e-0454413MM15202
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

5.39e-0455413M47952
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

PSME4 ITPR1 ITPR2 ITPR3

5.53e-04131414MM15717
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

PSME4 ITPR1 ITPR2 ITPR3

7.10e-04140414M27484
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

7.31e-0461413MM15071
PathwayREACTOME_CA2_PATHWAY

ITPR1 ITPR2 ITPR3

7.67e-0462413M27321
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

SPTB SPTBN1 CACNA1H

8.03e-0463413M11187
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

PSME4 ITPR1 ITPR2 ITPR3

8.30e-04146414M27288
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

PIK3CG RASGRP2 ITPR1 ITPR2 ITPR3

8.49e-04257415MM15454
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

PIK3CG RASGRP2 ITPR1 ITPR2 ITPR3

9.10e-04261415M1077
PathwayKEGG_LONG_TERM_POTENTIATION

ITPR1 ITPR2 ITPR3

1.09e-0370413M3115
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3

1.18e-0372413MM14631
PathwayWP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY

ITPR1 ITPR2 ITPR3

1.28e-0374413M48080
PathwayWP_ALZHEIMERS_DISEASE

ITPR1 ITPR2 ITPR3

1.28e-0374413MM15962
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

PSME4 ITPR1 ITPR2 ITPR3

1.34e-03166414M608
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

1.39e-0376413MM15051
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

1.49e-0378413M1921
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

ITPR1 ITPR2 ITPR3

1.72e-0382413M27110
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1H ITPR1 ITPR2 ITPR3

1.73e-03178414M2890
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

ITPR1 ITPR2 ITPR3

1.98e-0386413M601
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

1.98e-0386413M916
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

PSME4 BDNF ITPR1 ITPR2 ITPR3

2.03e-03313415M27867
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

KSR1 PSME4 SPTBN1 RNF213 CTBP1 BDNF

2.08e-03464416M27547
PathwayREACTOME_OPIOID_SIGNALLING

ITPR1 ITPR2 ITPR3

2.25e-0390413M6467
PathwayKEGG_GAP_JUNCTION

ITPR1 ITPR2 ITPR3

2.25e-0390413M4013
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

PSME4 RNF213 HERC1 HERC5 RASGRP2 ITPR1 ITPR2 ITPR3

2.32e-03828418M1058
PathwayREACTOME_SIGNALING_BY_WNT

PSME4 CTBP1 ITPR1 ITPR2 ITPR3

2.56e-03330415M7847
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

ITPR1 ITPR2 ITPR3

2.63e-0395413M29842
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

HELZ2 NOCT

2.77e-0327412M26943
PathwayREACTOME_MUSCLE_CONTRACTION

CACNA1H ITPR1 ITPR2 ITPR3

2.79e-03203414M5485
PathwayREACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT

SPTB SPTBN1 ARF5

3.21e-03102413M27648
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR1 ITPR2 ITPR3

3.30e-03103413MM15196
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

RASGRP2 ITPR1 ITPR2 ITPR3

3.54e-03217414M18437
PathwayREACTOME_SIGNALING_BY_VEGF

ITPR1 ITPR2 ITPR3

3.58e-03106413M27077
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTB SPTBN1

3.64e-0331412M877
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3

3.77e-03108413M17034
PathwayREACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT

SPTB SPTBN1 ARF5

3.97e-03110413MM15350
PathwayWP_BDNFTRKB_SIGNALING

PIK3CG BDNF

4.12e-0333412M39532
PathwayWP_RESISTIN_AS_A_REGULATOR_OF_INFLAMMATION

PIK3CG ITPR1

4.12e-0333412M39745
PathwayKEGG_OOCYTE_MEIOSIS

ITPR1 ITPR2 ITPR3

4.28e-03113413M16817
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

PSME4 RNF213 HERC1 RASGRP2 ITPR1 ITPR2 ITPR3

4.30e-03719417MM14540
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

PRSS3 PSME4 IGHE CFI HERC5 RASGRP2 ITPR1 ITPR2 ITPR3

4.40e-031128419M1036
PathwayWP_EFFECT_OF_OMEGA3_PUFA_ON_HUNTINGTONS_DISEASE_PATHWAYS

PIK3CG BDNF ITPR1

4.95e-03119413M48309
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2 ITPR3

4.17e-09357310874040
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2 ITPR3

4.17e-0935739808793
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2 ITPR3

4.17e-09357320395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2 ITPR3

4.17e-09357317437169
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2 ITPR3

4.17e-09357318194433
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2 ITPR3

4.17e-09357318547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2 ITPR3

4.17e-09357336350267
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2 ITPR3

4.17e-09357327777977
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2 ITPR3

4.17e-09357311413485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

4.17e-09357326009177
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2 ITPR3

4.17e-09357317581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2 ITPR3

4.17e-09357318241669
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2 ITPR3

4.17e-0935731693919
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2 ITPR3

4.17e-09357319068129
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2 ITPR3

4.17e-09357323955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2 ITPR3

4.17e-09357331979185
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2 ITPR3

4.17e-09357324904548
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

4.17e-09357317327232
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2 ITPR3

4.17e-09357316014380
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2 ITPR3

4.17e-09357317890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2 ITPR3

4.17e-09357323983250
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2 ITPR3

4.17e-0935739858485
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

4.17e-09357320427533
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2 ITPR3

1.67e-08457325215520
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2 ITPR3

1.67e-08457321424589
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2 ITPR3

1.67e-08457328615414
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2 ITPR3

1.67e-08457310828023
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2 ITPR3

1.67e-08457328419336
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

1.67e-08457311163362
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2 ITPR3

1.67e-08457335494252
Pubmed

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.

ITPR1 ITPR2 ITPR3

4.16e-08557321568942
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

ITPR1 ITPR2 ITPR3

8.32e-08657323463619
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

8.32e-08657321762810
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

ITPR1 ITPR2 ITPR3

8.32e-08657320519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

ITPR1 ITPR2 ITPR3

8.32e-08657325966694
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

ITPR1 ITPR2 ITPR3

8.32e-08657316844763
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

ITPR1 ITPR2 ITPR3

1.45e-07757311860456
Pubmed

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.

ITPR1 ITPR2 ITPR3

1.45e-07757322495310
Pubmed

Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.

ITPR1 ITPR2 ITPR3

3.48e-07957325737585
Pubmed

Type 1 and 3 inositol trisphosphate receptors are required for extra-embryonic vascular development.

ITPR1 ITPR2 ITPR3

6.82e-071157327514653
Pubmed

Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers.

ITPR1 ITPR2 ITPR3

1.50e-061457334630045
Pubmed

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.

ITPR1 ITPR2 ITPR3

1.87e-061557328578927
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

2.64e-0625729065779
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

2.64e-06257217496801
Pubmed

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor.

ITPR1 ITPR3

2.64e-0625728663526
Pubmed

The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.

ITPR1 ITPR3

2.64e-06257215890645
Pubmed

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.

ITPR2 ITPR3

2.64e-06257224901844
Pubmed

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.

ITPR2 ITPR3

2.64e-06257233854148
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

2.64e-06257218708078
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

2.64e-06257215201137
Pubmed

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.

ITPR2 ITPR3

2.64e-06257219528657
Pubmed

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

ITPR2 ITPR3

2.64e-0625728063813
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

2.64e-0625728081734
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

2.64e-06257223582047
Pubmed

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.

ITPR1 ITPR3

2.64e-0625721374893
Pubmed

In Vivo Structural and Functional Abnormalities of the Striatums Is Related to Decreased Astrocytic BDNF in Itpr2-/- Mice Exhibiting Depressive-Like Behavior.

BDNF ITPR2

2.64e-06257232952549
Pubmed

IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

ITPR2 ITPR3

2.64e-06257216195467
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

2.64e-06257215632133
Pubmed

Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening.

ITPR1 ITPR3

2.64e-06257220813840
Pubmed

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

ITPR2 ITPR3

2.64e-06257215713744
Pubmed

Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.

ITPR1 ITPR3

2.64e-0625727559486
Pubmed

Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

ITPR1 ITPR3

2.64e-06257220843799
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

2.64e-06257219120126
Pubmed

Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.

ITPR1 ITPR3

2.64e-06257214707143
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTB SPTBN1 ITGA3

3.35e-061857312119179
Pubmed

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.

ITPR1 ITPR2 ITPR3

6.29e-062257311696558
Pubmed

Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland.

ITPR2 ITPR3

7.91e-06357221435446
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTB SPTBN1

7.91e-06357211294830
Pubmed

Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP3R in the stomach and kidney.

ITPR1 ITPR3

7.91e-06357222992961
Pubmed

Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.

ITPR1 ITPR3

7.91e-06357212032348
Pubmed

Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.

ITPR1 ITPR2

7.91e-06357232320395
Pubmed

Ubiquitination and proteasomal degradation of endogenous and exogenous inositol 1,4,5-trisphosphate receptors in alpha T3-1 anterior pituitary cells.

ITPR1 ITPR3

7.91e-06357212421829
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

ITPR1 ITPR2

7.91e-06357223223241
Pubmed

Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA.

BDNF ITPR1

7.91e-06357216286649
Pubmed

The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.

SPTB SPTBN1

7.91e-0635728479293
Pubmed

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.

ITPR1 ITPR3

7.91e-06357218250332
Pubmed

β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.

SPTB SPTBN1

7.91e-06357232425157
Pubmed

Developmental expression of brain beta-spectrin isoform messenger RNAs.

SPTB SPTBN1

7.91e-0635721467942
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

ITPR1 ITPR2 ITPR3

8.24e-062457310843712
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PSME4 SPEG EMID1 HELZ2 CACNA1H SFI1 ITGA3 HERC1 ITPR2 ITPR3

1.12e-051105571035748872
Pubmed

Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.

ITPR1 ITPR2 ITPR3

1.48e-052957332123907
Pubmed

Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-trisphosphate receptor.

ITPR2 ITPR3

1.58e-05457217925404
Pubmed

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

ITPR1 ITPR2

1.58e-05457221818117
Pubmed

IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.

ITPR2 ITPR3

1.58e-05457226193638
Pubmed

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

SPTB SPTBN1

1.58e-05457221566095
Pubmed

Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.

SPTB SPTBN1

1.58e-0545723862089
Pubmed

Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs.

SPTB SPTBN1

1.58e-05457221412925
Pubmed

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.

ITPR1 ITPR3

1.58e-05457223884412
Pubmed

Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.

ITPR1 ITPR3

1.58e-05457214685260
Pubmed

Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.

ITPR1 ITPR3

1.58e-05457222082873
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

ITPR1 ITPR2

1.58e-05457219120137
Pubmed

Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.

SPTB SPTBN1

1.58e-05457212820899
Pubmed

Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association.

ITPR1 ITPR3

1.58e-05457211524429
Pubmed

Widespread expression of inositol 1,4,5-trisphosphate receptor type 1 gene (Insp3r1) in the mouse central nervous system.

ITPR1 ITPR3

2.63e-0555728081710
Pubmed

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum.

ITPR1 ITPR3

2.63e-05557215613488
Pubmed

BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.

ITPR1 ITPR2

2.63e-05557211782428
Pubmed

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.

ITPR1 ITPR3

2.63e-05557219706527
Pubmed

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

SPTBN1 CACNA1H

2.63e-05557229720258
Pubmed

Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling.

PIK3CG RASGRP2

2.63e-05557221480213
Pubmed

Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors.

ITPR2 ITPR3

2.63e-05557221436055
InteractionIRAG1 interactions

ITPR1 ITPR2 ITPR3

6.48e-0614543int:IRAG1
InteractionTESPA1 interactions

ITPR1 ITPR2 ITPR3

9.94e-0616543int:TESPA1
InteractionTRPC4 interactions

ITPR1 ITPR2 ITPR3

3.10e-0523543int:TRPC4
InteractionRASEF interactions

ITPR1 ITPR2 ITPR3

4.01e-0525543int:RASEF
InteractionBBOX1 interactions

ITPR1 ITPR2 ITPR3

6.32e-0529543int:BBOX1
InteractionTRPC1 interactions

ITPR1 ITPR2 ITPR3

6.32e-0529543int:TRPC1
InteractionTRPC2 interactions

ITPR1 ITPR3

7.01e-055542int:TRPC2
Cytoband22q12.2

PLA2G3 EMID1 SFI1

5.33e-055857322q12.2
Cytoband15q22

HERC1 RPL4

6.02e-042957215q22
CytobandEnsembl 112 genes in cytogenetic band chr15q22

HERC1 RPL4 MEGF11

6.07e-04132573chr15q22
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2 ITPR3

1.00e-083403297
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN1

9.95e-0574021113
GeneFamilyEMI domain containing

EMID1 EMILIN1

9.95e-057402540
CoexpressionGSE27786_LSK_VS_MONO_MAC_DN

PIK3CG HELZ2 SPIDR ITGA3 GPR108 ITPR2

4.33e-06200566M4765
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

PSME4 GPCPD1 RNF213 NOCT HERC1

1.70e-061565751545169694f686d28648a68b552c2ae606599d66
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

GPCPD1 RNF213 NOCT HERC1 ITPR1

4.24e-06188575ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

SPEG SPTB CACNA1H ITGA3 RASGRP2

4.58e-061915752da83c493e60ad0278848957645277d76737a188
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG EMID1 CACNA1H BDNF RASGRP2

4.94e-06194575b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG EMID1 CACNA1H BDNF RASGRP2

5.07e-061955750bdf845939bc4b8cc94f2808aea60f818425b076
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG CACNA1H ITGA3 RASGRP2 ITPR1

5.32e-0619757571367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG CACNA1H ITGA3 RASGRP2 ITPR1

5.32e-061975750f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PSME4 SFI1 SPIDR ITGA3 ITPR1

5.73e-062005750d76b006d8e8b32174e65e400acd0674354b962c
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PSME4 SFI1 SPIDR ITGA3 ITPR1

5.73e-06200575cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GFRAL SPTB EMID1 ZNF416

4.19e-05151574bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C-8|TCGA-Thymus / Sample_Type by Project: Shred V9

IGHE PLA2G3 HEPACAM2 NOCT

4.64e-0515557400eef9f93a753a1fe1ab5fd8dae026e7be556cde
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGLC7 IGHE RPL4 ITPR1

4.64e-05155574d336559092563b0d7776eef873f1d2759aca45f7
ToppCellPBMC-Control-cDC_1|Control / Compartment, Disease Groups and Clusters

NPIPB15 HELZ2 RNF213 HERC5

4.76e-051565749b6c5bcac516a62bcc1f5be32ffa8c92735ef0bc
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

RNF213 CARD16 ITGA3 HERC5

5.13e-0515957497c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

RNF213 CARD16 ITGA3 HERC5

5.13e-05159574fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SPEG SPTBN1 SFI1 ITPR1

5.51e-05162574b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 SETD4 ITGA3 CFI

5.92e-05165574936581de8fcd097401707438b9bbe89dd4e3e247
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

NPIPB7 SPTB EMILIN1 HERC5

6.96e-05172574c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG EMID1 SESN2 BDNF

7.11e-051735743059325901b1e5e12a1a91183f14267288b2f600
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

KSR1 CARD16 ITGA3 ITPR3

7.11e-05173574efb8072475000888efe088d00e870c56ffad4172
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG EMID1 SESN2 BDNF

7.11e-0517357436c8338463ee4cc432f568728d55989360f9a68d
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPTB HEPACAM2 EMILIN1 ITPR2

7.44e-05175574a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

PRSS3 SPTBN1 EMID1 TLCD5

7.60e-05176574b9da3deaf62622d47eb30b6be7548253eee95597
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

MLH3 RNF213 SFI1 NOCT

7.60e-051765743de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

MLH3 RNF213 SFI1 NOCT

7.77e-0517757482fdd6185b368f54f03de389427cbe3071d21a99
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

IGHE SPTBN1 ITGA3 BDNF

8.12e-05179574d5763912a4ce7188535675e338799b856edb9dda
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PSME4 SPTB HEPACAM2 HERC1

8.66e-051825740c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellNS-moderate-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF213 CARD16 HERC5 ITPR2

8.66e-05182574e03e995e5fd14fc6a7559b83c0ca4e7ccc8e3d0f
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

PSME4 SPIDR NOCT ITPR2

9.03e-051845749c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

SPEG CACNA1H BDNF RASGRP2

9.03e-0518457483987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCellTuft|World / Class top

PIK3CG SPTB HEPACAM2 ITPR2

9.41e-05186574f4d83f15ab7b49c0920a322cd832413ece7c9948
ToppCellTuft-tuft-2|World / Class top

PIK3CG SPTB HEPACAM2 ITPR2

9.61e-051875744ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF213 ITGA3 MEGF11 ITPR3

1.00e-04189574aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPTB GPCPD1 HEPACAM2 HERC1

1.00e-041895741900e574870fc647bfa11c732a72f3d38aab717c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF213 ITGA3 MEGF11 ITPR3

1.00e-041895748977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG EMID1 BDNF RASGRP2

1.04e-04191574ff7874cc005760a8f3b2e8072fbe418b6bfacaa8
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GPCPD1 RNF213 SFI1 NOCT

1.04e-041915749454f642c3621370fa23640b631301346b300950
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG SLC4A5 EMILIN1 RASGRP2

1.04e-0419157496ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 ITGA3 NOCT RPL4

1.06e-0419257418546b4d5e39aafa97186104d47cfda02eb5f4b5
ToppCellCV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

HELZ2 RNF213 CARD16 HERC5

1.06e-041925742a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

GPCPD1 RNF213 SFI1 HERC1

1.06e-0419257447646d7e4990be85072987f92bf18d52f8da752e
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 CACNA1H BDNF RASGRP2

1.06e-0419257488472b99970ba0decbf87164fc241a1c77b3b389
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG CACNA1H BDNF RASGRP2

1.09e-04193574b9e11cd0896c0868aab7faec4ab7ab4d4e4d1b47
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG CACNA1H ITGA3 RASGRP2

1.09e-041935745260ac95a15cc43a19909badad0c7e3854da920d
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG CACNA1H ITGA3 RASGRP2

1.09e-041935745ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG CACNA1H BDNF RASGRP2

1.11e-04194574fb234d97191c95b7880280c6e4ed5df124ffb0e1
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HELZ2 RNF213 CARD16 HERC5

1.11e-04194574267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

HELZ2 RNF213 CARD16 HERC5

1.13e-041955741992a1673b7213e25f3c76ac77da35c57daceddd
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

HELZ2 RNF213 CARD16 HERC5

1.13e-04195574b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell(01)_IL1RL1+-(1)_GFP|(01)_IL1RL1+ / shred by cell type by condition

PRSS3 GPCPD1 ITGA3 ARF5

1.15e-04196574b598b1112242534e139318012b257ed3cb09da83
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

HELZ2 GPCPD1 RNF213 HERC5

1.15e-041965743729d1444c65cad640377894decc64129bc3fd5b
ToppCellCV-Moderate-1|Moderate / Virus stimulation, Condition and Cluster

HELZ2 RNF213 CARD16 HERC5

1.15e-04196574b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCellmetastatic_Brain-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

GPCPD1 CARD16 RPL4 RASGRP2

1.15e-04196574d1a2768a1d0e5928fbd9debb7dcd7436134e09f6
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPEG CACNA1H ITGA3 RASGRP2

1.15e-04196574541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCellCV-Moderate-1|CV / Virus stimulation, Condition and Cluster

HELZ2 RNF213 CARD16 HERC5

1.17e-04197574e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group

RNF213 CARD16 CFI MEGF11

1.17e-0419757472a29a796b253a35c8772117a800d2a72fd89a3f
ToppCellsevere-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HELZ2 RNF213 CARD16 HERC5

1.17e-04197574c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCellCD8+_Memory_T_cell-CV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

HELZ2 RNF213 CARD16 HERC5

1.17e-04197574e59b47bccc781b2117196fe322efa87559c237c6
ToppCellcontrol-Myeloid-Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HELZ2 RNF213 CARD16 HERC5

1.17e-041975748819db1550bf14566c6d33d97f7f83419e867ace
ToppCellsevere-Myeloid-Neutrophils_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HELZ2 RNF213 CARD16 HERC5

1.20e-04198574636878836678a0715550fa09f2e3dac11c4d73fe
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

MLH3 EMID1 EMILIN1 ITPR1

1.20e-04198574e0e47cf65774191981840b22905b2094b95abe0f
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

HELZ2 RNF213 CARD16 HERC5

1.20e-04198574ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG SPTB CACNA1H ITPR1

1.20e-041985741e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

HELZ2 RNF213 CARD16 HERC5

1.20e-041985744b078714c49e7befb7b113d72485e712236d35fa
ToppCellBAL-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

HELZ2 RNF213 CARD16 HERC5

1.22e-041995749f5750212b887f92761ade33fc6e108cd5275297
ToppCellControl-Control-Lymphocyte-B-Plasmablast|Control / Disease, condition lineage and cell class

NPIPB15 IGLC7 IGHE NPIPB6

1.22e-04199574c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

HELZ2 RNF213 CARD16 HERC5

1.22e-04199574c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG SPTB CACNA1H RASGRP2

1.22e-041995740a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

HELZ2 RNF213 CARD16 HERC5

1.22e-04199574056a0538ca5e825ae6195b4c76c208708a014533
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

SPTBN1 HELZ2 RNF213 HERC5

1.22e-04199574952fac67588ad5676f5939e3c7f8bac803c27064
ToppCelldistal-2-mesenchymal-Airway_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPEG SPTB CACNA1H EMILIN1

1.22e-04199574af226a6c50747dad9ca696463e715913b3ac17c0
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG SPTB CACNA1H RASGRP2

1.22e-04199574c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

SPTBN1 HELZ2 RNF213 HERC5

1.24e-04200574edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SPTBN1 HELZ2 RNF213 HERC5

1.24e-0420057489821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

SPTBN1 HELZ2 RNF213 HERC5

1.24e-04200574d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCelldistal-mesenchymal-Airway_Smooth_Muscle-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPEG SPTB CACNA1H EMILIN1

1.24e-04200574f09eaa52e11262ec47f3dcb4d890e240eaaa2b3d
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

SPTBN1 HELZ2 RNF213 HERC5

1.24e-04200574be55cef682ba87250dad97689332c8820b3a7420
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CACNA1H RPL4 RASGRP2

1.96e-04885733a92f76e4db86486cb265301e6056af791a11a63
ToppCellhuman_hepatoblastoma-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SLC10A6 CACNA1H ITPR2

2.77e-0499573eeb2d10170154c61717c38f85d0fbb61c4c48bb3
DrugNorcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

PLA2G3 EMID1 CACNA1H SFI1 SPIDR ITPR1

4.72e-061805564776_UP
Drugadenophostin A

ITPR2 ITPR3

5.73e-062552ctd:C085029
DrugIsocaffeine

ITPR1 ITPR3

5.73e-062552CID000001326
Drugadenophostin B

ITPR1 ITPR3

5.73e-062552CID000656722
Drugbenzene 1,2,4-trisphosphate

ITPR1 ITPR3

5.73e-062552CID000192376
DrugEpiandrosterone [481-29-8]; Up 200; 13.8uM; PC3; HT_HG-U133A

KSR1 SPEG EMID1 SFI1 RASGRP2 ITPR2

7.26e-061945564626_UP
DrugPepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A

SPEG PLA2G3 CACNA1H SFI1 HERC5 ITPR1

8.39e-061995563264_UP
Drug5-deoxy-5-fluoro-myo-inositol

ITPR1 ITPR3

1.72e-053552CID000195110
DrugCHEBI:697555

ITPR1 ITPR3

3.43e-054552CID009578246
DrugAC1OAGFB

PIK3CG SPTB SPTBN1 HERC1 RASGRP2 ITPR1 ARF5 ITPR3

4.29e-05539558CID006857345
DrugXeC compound

PIK3CG BDNF ITPR1 ITPR3

5.09e-0584554CID000005701
Druglavendustin A

PIK3CG CARD16 CACNA1H ITPR1 ITPR3

5.79e-05171555CID000003894
DrugCNS 1145

CACNA1H ITPR1 ITPR3

6.91e-0533553CID000190902
DrugIHC-64

CACNA1H ITPR1 ITPR3

6.91e-0533553CID000162753
DrugAC1L1DXE

PRSS3 PIK3CG CACNA1H BDNF ITPR1 ITPR3

8.24e-05299556CID000002548
DrugAC1Q7BER

ITPR1 ITPR3

8.54e-056552CID000005702
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

SPTB SPTBN1 EMID1 HERC5 ITPR2

1.00e-041925552523_UP
Drug2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; MCF7; HT_HG-U133A

PSME4 SPEG EMID1 NOCT HERC5

1.00e-041925553400_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A

PIK3CG SFI1 SPIDR RASGRP2 ITPR3

1.03e-041935552675_DN
DrugNorgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A

SPTBN1 PLA2G3 ZNF287 ITPR1 ITPR3

1.03e-041935553708_UP
DrugMethyldopa (L,-) [555-30-6]; Up 200; 19uM; HL60; HG-U133A

TNPO1 MLH3 PIK3CG SETD4 RASGRP2

1.08e-041955551619_UP
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A

SPEG SPTB SPTBN1 EMID1 HERC5

1.10e-041965552871_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A

MLH3 ZBTB5 SPIDR NOCT BDNF

1.10e-041965551158_UP
DrugGuanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

SPTB PLA2G3 SFI1 ITPR1 ITPR2

1.13e-041975555703_UP
DrugClofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

SPTBN1 EMID1 CACNA1H SFI1 SPIDR

1.13e-041975553239_DN
Drug0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A

PLA2G3 SFI1 SLC4A5 ITPR1 ITPR2

1.13e-041975553693_UP
Drug2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A

MLH3 PIK3CG CTBP1 SFI1 RASGRP2

1.16e-041985551163_UP
DrugProcainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A

PRSS3 SPTBN1 SFI1 ITPR1 ITPR3

1.16e-041985555663_UP
DrugBacitracin [1405-87-4]; Down 200; 2.8uM; MCF7; HT_HG-U133A

MLH3 PSME4 SPTBN1 EMID1 NOCT

1.16e-041985556488_DN
DrugCefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A

EMID1 CACNA1H SFI1 NOCT ITPR1

1.16e-041985553581_DN
DrugDiphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

SPTB EMID1 CACNA1H RASGRP2 ITPR1

1.18e-041995556020_UP
Drug3-F-InsP3

ITPR1 ITPR3

1.19e-047552CID003035756
DrugBr2BAPTA

ITPR1 ITPR3

1.19e-047552CID003081001
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

ITPR1 ITPR3

1.19e-047552CID009547999
Drug9 mM of H

ITPR1 ITPR3

1.59e-048552CID000130464
Drugbasic copper carbonate

ITPR1 ITPR3

1.59e-048552CID000025503
DrugNs 004

ITPR1 ITPR3

1.59e-048552CID000162750
DrugF2 g

ITPR1 ITPR3

1.59e-048552CID006857713
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2 ITPR3

1.26e-0612543DOID:1441 (implicated_via_orthology)
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

3.29e-062542C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

3.29e-062542C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

3.29e-062542C0995195
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

3.29e-062542C1140716
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN1

1.97e-054542DOID:0050882 (implicated_via_orthology)
Diseasegrip strength measurement

PRSS3 PSME4 NPIPB6 BDNF ITPR1

4.48e-04350545EFO_0006941
DiseaseLynch syndrome (is_implicated_in)

MLH3 ASTE1

8.84e-0424542DOID:3883 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
CLRASKTHRYQIWTT

CFI

381

P05156
KRHWNSQCRTTQSYV

BDNF

201

P23560
STLCHILNLYRRATW

CTBP1

131

Q13363
QHLRSRTWYVQATCA

ARF5

146

P84085
ITLDCQNIYTWKSRH

ASCC1

86

Q8N9N2
SKNRGRTTAHTKCWY

ASTE1

641

Q2TB18
RTTAHTKCWYEGNNR

ASTE1

646

Q2TB18
YVRLRHLCTNTWVTS

ITPR2

386

Q14571
YVRLRHLCTNTWIQS

ITPR3

386

Q14573
DILNWFKCTRHRISY

MEGF11

56

A6BM72
LQVKTCHLVRYWISA

RASGRP2

71

Q7LDG7
SYVRLRHLCTNTWVH

ITPR1

386

Q14643
RILHRTDRWTYCINK

HERC1

2221

Q15751
RVLVCAHRYTQVLWS

ITGA3

136

P26006
VTHRFSTKSWLSQVC

KSR1

346

Q8IVT5
TVTEEQRRLLWCYHK

MLH3

1266

Q9UHC1
VCWRSLSLKSHQRVS

CSNKA2IP

166

A0A1B0GTH6
LSKLRTRHCTQAWAI

NPIPB7

396

O75200
WHRRVNTTQKRYAIC

RPL4

111

P36578
SKLRTRHCTQAWAIR

NPIPB15

406

A6NHN6
RVTQIACGRWHTLAY

HERC5

296

Q9UII4
WLTCQTEIRLRLHYS

GPCPD1

126

Q9NPB8
HYRTFQSKCWQRVTR

GFRAL

236

Q6UXV0
SQKHWLSDRTYTCQV

IGHE

181

P01854
SVRYTHQLCLLKWIS

MARCHF11

191

A6NNE9
PEQWKSHRSYSCRVT

IGLC7

76

A0M8Q6
SWIRRTDNTTYIIKH

HEPACAM2

281

A8MVW5
WCSYVVTRTISCHVQ

EMID1

36

Q96A84
HRNWCAYVVTRTVSC

EMILIN1

56

Q9Y6C2
WRYVLVSTVRTCAKS

HELZ2

2556

Q9BYK8
NISTKAQCRAAHYRW

CACNA1H

1466

O95180
RLSKLRTRHCTQAWA

NPIPB6

406

E9PJ23
CHVQNTIIKWSERYT

CARD16

131

Q5EG05
LSKLRTRHCTQAWAI

NPIPB9

411

F8W1W9
YTTWKIRTSGECRHT

NOCT

361

Q9UK39
HYRRTICSKVLVQWR

SFI1

711

A8K8P3
LHYQTTKQNLWSCRR

SFI1

1161

A8K8P3
TSVLRRAIWNYIHCV

SESN2

386

P58004
ILCRNTYSVFKIHWL

GPR108

281

Q9NPR9
KWRLSHCTVHRTDLY

NEPRO

486

Q6NW34
THSYEIRTTSRWRKH

SETD4

251

Q9NVD3
VSIYCSMRKRSLSHW

SLC38A8

236

A6NNN8
QCILQHTWTERKFYT

NPAP1

1121

Q9NZP6
SPALRWYRTSCHLTK

PLA2G3

21

Q9NZ20
TKWVNSHLARVSCRI

SPTBN1

61

Q01082
VQTLDCLRYWKATHR

PIK3CG

116

P48736
WSCRKRITVEYLQHI

RNF213

4741

Q63HN8
LNKHRSYEWSCRLVT

TLCD5

26

Q6ZRR5
ILKWVVSHQSCSRSS

TTLL8

216

A6PVC2
LYKHSKTTCLRWQSS

ZBTB5

656

O15062
CWKVFSQSTYLIRHQ

ZNF287

541

Q9HBT7
RWQRSQISYKCHLVL

SPEG

1876

Q15772
AISLWRHQCISYQKT

SPIDR

276

Q14159
GIHCIARKRSSSWSY

SLC4A5

1121

Q9BY07
LFTHQSWQRCRTISL

SLC10A6

246

Q3KNW5
TKWVNSHLARVSCRI

SPTB

61

P11277
LKQTARSSSWHARYT

PSME4

1646

Q14997
LVRSITCWTLSRYAH

TNPO1

461

Q92973
SEQWVVSAAHCYKTR

PRSS3

111

P35030
GISHYKWSQCRRESS

ZNF416

211

Q9BWM5