Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentactin-based cell projection

RIPOR2 CYFIP1 FZD3 FSCN3 BBS2 CUBN TENM2

2.00e-05278637GO:0098858
GeneOntologyCellularComponentfilopodium

RIPOR2 CYFIP1 FZD3 FSCN3 TENM2

3.48e-05123635GO:0030175
DomainTSP_1

ADAMTS12 CILP ADAMTS3 SEMA5A

5.31e-0563614PF00090
DomainTSP1

ADAMTS12 CILP ADAMTS3 SEMA5A

6.01e-0565614SM00209
DomainTSP1_rpt

ADAMTS12 CILP ADAMTS3 SEMA5A

6.01e-0565614IPR000884
DomainTSP1

ADAMTS12 CILP ADAMTS3 SEMA5A

6.01e-0565614PS50092
Domain-

FSTL3 LTBP2

2.90e-0486123.90.290.10
DomainTB

FSTL3 LTBP2

3.72e-049612PS51364
DomainTB_dom

FSTL3 LTBP2

3.72e-049612IPR017878
DomainCarboxyPept-like_regulatory

CILP TENM2

1.38e-0317612IPR008969
DomainPLAC

ADAMTS12 ADAMTS3

1.73e-0319612PS50900
DomainPLAC

ADAMTS12 ADAMTS3

1.73e-0319612IPR010909
DomainADAM_spacer1

ADAMTS12 ADAMTS3

2.54e-0323612IPR010294
DomainADAM_spacer1

ADAMTS12 ADAMTS3

2.54e-0323612PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS12 ADAMTS3

2.77e-0324612IPR013273
DomainPeptidase_M12B_N

ADAMTS12 ADAMTS3

7.19e-0339612IPR002870
DomainPep_M12B_propep

ADAMTS12 ADAMTS3

7.19e-0339612PF01562
DomainEGF_CA

LTBP2 CUBN TENM2

7.43e-03122613SM00179
DomainDISINTEGRIN_1

ADAMTS12 ADAMTS3

7.56e-0340612PS00427
DomainReprolysin

ADAMTS12 ADAMTS3

7.56e-0340612PF01421
DomainADAM_MEPRO

ADAMTS12 ADAMTS3

7.56e-0340612PS50215
DomainDISINTEGRIN_2

ADAMTS12 ADAMTS3

7.56e-0340612PS50214
DomainPeptidase_M12B

ADAMTS12 ADAMTS3

7.56e-0340612IPR001590
DomainEGF-like_Ca-bd_dom

LTBP2 CUBN TENM2

7.77e-03124613IPR001881
DomainDisintegrin_dom

ADAMTS12 ADAMTS3

7.93e-0341612IPR001762
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS3 SEMA5A

1.94e-0439413M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS3 SEMA5A

1.94e-0439413MM15165
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS3 SEMA5A GALNT4

2.75e-04109414MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS3 SEMA5A GALNT4

2.95e-04111414M27416
Pubmed

7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4.

MAP2K4 MAP3K8

3.33e-06264221378167
Pubmed

The protein-tyrosine kinase fer associates with signaling complexes containing insulin receptor substrate-1 and phosphatidylinositol 3-kinase.

FER IRS1

3.33e-06264211006284
Pubmed

Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors.

HLA-DPB1 TAPBP

9.99e-06364216322289
Pubmed

Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.

MAP2K4 MAP3K8

9.99e-0636428631303
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS12 ADAMTS3 SEMA5A CUBN

1.15e-057564420637190
Pubmed

Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells.

FLNC MAP2K4

4.98e-0566429006895
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

FZD3 SEMA5A CUBN DCBLD2

6.61e-0511764417145500
Pubmed

Genome-wide association of serum uric acid concentration: replication of sequence variants in an island population of the Adriatic coast of Croatia.

SEMA5A TENM2

6.96e-05764222229870
Pubmed

Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.

CYFIP1 AIMP2 NMRAL1 UBLCP1

1.44e-0414364432560809
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

CYFIP1 AOC1 CILP ACP1 HPX SEMA5A LTBP2 CUBN CR1

1.44e-04107064923533145
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS12 ADAMTS3

1.49e-041064211167130
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM2 ADGRL3

1.49e-041064238713721
Pubmed

Genetic loci that control the angiogenic response to basic fibroblast growth factor.

ENPP2 SEMA5A

3.93e-041664215226265
Pubmed

Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.

AOC1 CUBN

4.45e-041764221082674
Pubmed

REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain.

RIPOR2 UNC13A

5.00e-041864228049845
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ADAMTS12 FSTL3 ENPP2 CR1 TENM2 GALNT4

5.35e-0455264610737800
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

LRIG3 FLNC COL13A1 AIMP2

6.63e-0421464422199357
Pubmed

Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability.

COL13A1 ENPP2

7.52e-042264215733672
Pubmed

Klf14 is an imprinted transcription factor that regulates placental growth.

ENPP2 LTBP2

8.23e-042364231675530
Pubmed

Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.

CUBN GALNT4

8.96e-042464231740596
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

ADAMTS12 ADAMTS3

8.96e-042464232212159
Pubmed

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

FZD3 MAP3K8

8.96e-04246428626800
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PALD1 LRIG3 RIPOR2 TENM2 ADGRL3

9.27e-0440764512693553
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FSTL3 ACP1 MANEAL CD70 LTBP2 DCBLD2 TAPBP GALNT4

1.58e-03120164835696571
CytobandEnsembl 112 genes in cytogenetic band chr7q32

FLNC FSCN3 KCP

3.47e-0497643chr7q32
Cytoband19p13

FSTL3 CD70

6.57e-042764219p13
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS12 ADAMTS3

8.37e-041941250
GeneFamilyC1-set domain containing

HLA-DPB1 TAPBP

4.08e-0342412591
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_1000

TRMT9B LRIG3 ZBTB46 POLR3B COL13A1 CILP ADAMTS3 NMRAL1 GNL2 TENM2 ADGRL3

2.80e-058556111gudmap_developingKidney_e13.5_podocyte cells_1000
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS12 ZBTB46 COL13A1 SEMA5A ADGRL3

5.94e-06179645a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZBTB46 HIVEP1 AOC1 HLA-DPB1 CD70

6.97e-061856457e3d9f5050e71e91021245c11101e994ae41d22b
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

ZBTB46 COL13A1 CILP SEMA5A LTBP2

7.35e-06187645e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell5'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIPOR2 HLA-DPB1 MAP3K8 CD70 CR1

8.14e-06191645ce0217d375af6b19252a45340b72241ea7b204d4
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL13A1 SEMA5A DCBLD2 UBLCP1 ADGRL3

8.35e-061926451d0d6fb89a2b941b7caab2f1f07d6bd5433a11e7
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ADAMTS12 COL13A1 ENPP2 ST6GALNAC5 LTBP2

8.35e-0619264562904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

RIPOR2 HLA-DPB1 FER CD70 CR1

8.56e-061936457ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell3'_v3-Lung-Myeloid_Dendritic|Lung / Manually curated celltypes from each tissue

PALD1 ZBTB46 AOC1 HLA-DPB1 ENPP2

9.00e-06195645b748cb15846345363e8c2ee5936bb42bba3ba9a7
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

ADAMTS12 COL13A1 ST6GALNAC5 LTBP2 ADGRL3

9.00e-06195645603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AOC1 DET1 FZD3 UNC13A ADGRL3

9.69e-06198645d6812494874be0c14361ac2ac3e418b335bb8f55
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS12 COL13A1 FSTL3 ENPP2 LTBP2

9.93e-061996457f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS12 COL13A1 FSTL3 ENPP2 LTBP2

9.93e-06199645301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS12 COL13A1 FSTL3 ENPP2 LTBP2

9.93e-061996459a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 COL13A1 CILP LTBP2

1.48e-0510364439d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 COL13A1 CILP LTBP2

1.48e-0510364401a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 COL13A1 CILP LTBP2

1.54e-0510464411d91471b6c4fa6b00a91d9fd4db72ee60d1f801
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 COL13A1 CILP LTBP2

1.54e-05104644424a58b04c8b5108b70f15d8353c8e4b9db1e730
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 COL13A1 CILP LTBP2

1.54e-051046449b05ae514437eb0c8b1b23607ae8cbc371ffa85b
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ADAMTS12 TCAF2 FLNC COL13A1

2.79e-051216445035e071033cb76a7fc0128716755b14821e8f05
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ADAMTS12 TCAF2 FLNC COL13A1

2.79e-05121644c96115bd33455296378a257583b49442d00b39ca
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 COL13A1 CILP LTBP2

3.92e-05132644893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

FLNC COL13A1 CILP LTBP2

4.16e-05134644b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLNC FSTL3 FZD3 LTBP2

6.29e-05149644dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL13A1 ENPP2 SEMA5A TENM2

6.29e-05149644aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Thalamus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 FLNC COL13A1 LTBP2

6.97e-05153644e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 FLNC COL13A1 LTBP2

6.97e-05153644b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP|Thalamus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 FLNC COL13A1 LTBP2

6.97e-051536442513edfae62a44e51d3556675a096723194c966c
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

PALD1 LRIG3 ENPP2 CR1

7.51e-051566449a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellASK428-Immune-Mast_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL13A1 FAM83F FER TENM2

8.91e-05163644569ca0e8ce307f258910b0c75c498009a9651e6e
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRMT9B FAM153B FSCN3 UNC13A

9.34e-051656444b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 FLNC COL13A1 LTBP2

9.34e-05165644570483b43ccb5831feec9337b4664814431d40b1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 FLNC COL13A1 LTBP2

9.34e-051656442026a9a07f4d314cc05c167e491312b373468e46
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

COL13A1 FAM83F FER TENM2

1.00e-04168644c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS12 FSTL3 CILP SEMA5A

1.00e-04168644a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALD1 CYFIP1 HLA-DPB1 TENM2

1.02e-04169644a0681317867e31319210a23e56660a53f4529efe
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC ENPP2 KCP DCBLD2

1.15e-0417464468a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRMT9B HIVEP1 MAP3K8 SEMA5A

1.15e-0417464499eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC KCP TENM2 DCBLD2

1.20e-041766449df7a124ebafb0087da0cda133a394275d7bed81
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRMT9B ENPP2 KCP LTBP2

1.22e-0417764465709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCellControl-Myeloid-pDC|Control / Disease state, Lineage and Cell class

PALD1 HIVEP1 ENPP2 SEMA5A

1.22e-041776443940663bb5b45b2ca9f772550380a516c53e410b
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENPP2 HPX CUBN LONRF3

1.22e-0417764416197068260fc062bf8b730a51a199887ea580b9
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRMT9B ENPP2 KCP LTBP2

1.22e-041776448684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellControl-Myeloid-pDC|World / Disease state, Lineage and Cell class

PALD1 HIVEP1 ENPP2 SEMA5A

1.25e-0417864420ef63d925e67ddd5955832312ca8574a6f838a4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ST6GALNAC5 SEMA5A LONRF3 DCBLD2

1.25e-04178644a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

RIPOR2 ADAMTS3 ST6GALNAC5 CR1

1.28e-04179644cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRMT9B MAP3K8 RXFP2 SEMA5A

1.28e-04179644f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCellIPF-Epithelial-Mesothelial|IPF / Disease state, Lineage and Cell class

FLNC FAM153B ADAMTS3 SEMA5A

1.31e-041806441fa54bf4dba72866b2295639d991af639341bc08
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

PALD1 AOC1 HLA-DPB1 ENPP2

1.31e-04180644289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

ADAMTS12 ZBTB46 SEMA5A ADGRL3

1.33e-041816448dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell3'_v3-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

PALD1 HIVEP1 HLA-DPB1 SEMA5A

1.33e-0418164466d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

ADAMTS12 FSTL3 CILP LTBP2

1.33e-04181644bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

FLNC KCP TENM2 DCBLD2

1.36e-04182644287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RIPOR2 FZD3 HLA-DPB1 NMRAL1

1.39e-04183644983ca1342ddd365e1f1df32a456394b002b10e41
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRMT9B MAP3K8 RXFP2 SEMA5A

1.39e-0418364465f2a5895d166189a095cf7ea9dda171f0419b08
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

ADAMTS12 FLNC IRS1 LTBP2

1.42e-041846440b336489c10e8c3c957795dd845454f03404382b
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RIPOR2 HPX CR1 ADGRL3

1.42e-041846447ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC COL13A1 FSTL3 PPIL6

1.42e-04184644e33e2a887aafba7b6a31f00bb0dbe974b4359fd6
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD163+CD14+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

PALD1 HLA-DPB1 MAP3K8 ENPP2

1.42e-041846442dc4b2a9970111ed5e2977fc178595a12d7bb59d
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

TRMT9B FLNC CILP LTBP2

1.45e-04185644506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

FLNC FAM153B ADAMTS3 SEMA5A

1.45e-0418564423579988036fc1925992c31919750f9b3fe9f790
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

ADAMTS12 ZBTB46 SEMA5A ADGRL3

1.45e-04185644ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RIPOR2 HIVEP1 HLA-DPB1 CD70

1.48e-041866441a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCellcontrol-Myeloid-pDC|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PALD1 FZD3 ENPP2 SEMA5A

1.48e-04186644fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RIPOR2 HIVEP1 HLA-DPB1 CD70

1.48e-04186644f1366638edaecad5cad6367440f4c693513bed7e
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB46 AOC1 HLA-DPB1 ENPP2

1.48e-04186644a558fd00053e7dd6216b01dc8e650c30cee451f1
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PALD1 HLA-DPB1 ENPP2 LTBP2

1.48e-041866449673367cb53bafb873a01ef6bda11d9f392ce648
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIPOR2 HLA-DPB1 CD70 CR1

1.48e-04186644b5e094850ac3785775393cd78a939b02339732b0
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB46 AOC1 HLA-DPB1 ENPP2

1.48e-0418664475b1f342be5d6dbe0e7acd924a0ca75964f6bab0
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB46 AOC1 HLA-DPB1 ENPP2

1.48e-041866440c3d195077de7b4c354c127a26116438aef29244
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

ADAMTS12 COL13A1 ENPP2 LTBP2

1.51e-04187644e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RIPOR2 SEMA5A LTBP2 KLHDC8B

1.51e-041876441aebf6fab40b96f2f5feb77a302bb805838fccf3
ToppCellControl-Myeloid-DC_Mature|World / Disease state, Lineage and Cell class

ZBTB46 HIVEP1 AOC1 CD70

1.51e-0418764451bfc450e78284796b02317e91830357850b5437
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ADAMTS12 COL13A1 LTBP2 TENM2

1.51e-04187644bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIPOR2 HLA-DPB1 CD70 CR1

1.54e-041886447b56c680e9f1851cb961b0f8faeeb987685ae36d
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC ENPP2 BBS2 DCBLD2

1.54e-04188644aa516273cdde53c8c0295f06830972388f890c97
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC FSTL3 IRS1 LTBP2

1.54e-04188644c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellCOVID-19_Mild-pDC|COVID-19_Mild / Disease condition and Cell class

PALD1 FZD3 ENPP2 SEMA5A

1.54e-0418864462d33d2990d4a2d32bd0863147e47f656df1966e
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LRIG3 CILP SEMA5A DCBLD2

1.54e-041886440e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCellCOVID-19_Mild-pDC-|COVID-19_Mild / Disease condition and Cell class

PALD1 FZD3 ENPP2 SEMA5A

1.54e-04188644a75c2cf2f8dae343c13aaa66b637658b935ed10a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 COL13A1 ADAMTS3 SEMA5A

1.57e-04189644a153b83314cf52808f685296cff8c95af3f4983d
ToppCell10x_3'_v3-spleen_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RIPOR2 MAP3K8 CR1 TAPBP

1.57e-041896440fe8901e10c619c93b7788792da1706a32102c6e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PALD1 ZBTB46 HLA-DPB1 ENPP2

1.57e-04189644e97c64609b1f8158d750edb869df56e5bd10538b
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

PALD1 HLA-DPB1 ENPP2 SEMA5A

1.61e-04190644dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAMTS12 COL13A1 ENPP2 LTBP2

1.61e-0419064471e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

PALD1 HLA-DPB1 ENPP2 SEMA5A

1.61e-041906446892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC2|Lung / Manually curated celltypes from each tissue

PALD1 ZBTB46 HLA-DPB1 ENPP2

1.61e-04190644468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL13A1 FSTL3 IRS1 ADGRL3

1.61e-04190644591310e615700321a010a4b90405cbbbbdb3aade
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

PALD1 AOC1 HLA-DPB1 ENPP2

1.64e-04191644c3ff4342e0eea1e1f071b1fbca14a6dd4df0c696
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 COL13A1 ADAMTS3 SEMA5A

1.64e-04191644b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

PALD1 FZD3 ENPP2 SEMA5A

1.64e-0419164493adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL13A1 LTBP2 UNC13A ADGRL3

1.64e-0419164404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 COL13A1 ADAMTS3 SEMA5A

1.67e-041926446f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ENPP2 IRS1 LTBP2 ADGRL3

1.67e-0419264472881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 COL13A1 ADAMTS3 SEMA5A

1.67e-04192644dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-Memory_B_cells|GI_large-bowel / Manually curated celltypes from each tissue

RIPOR2 HLA-DPB1 CD70 CR1

1.67e-0419264431f7245bce79969674a775ecf175e7c6af68b503
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 COL13A1 ADAMTS3 SEMA5A

1.67e-04192644deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS12 COL13A1 FSTL3 LTBP2

1.71e-041936445bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

ADAMTS12 COL13A1 LTBP2 TENM2

1.71e-04193644ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 COL13A1 ADAMTS3 SEMA5A

1.71e-04193644fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL13A1 ENPP2 SEMA5A ADGRL3

1.71e-0419364468089ba4123e2f9bea9aae0023a844b5a57bfc0e
Diseasesevere acute respiratory syndrome, COVID-19

ADAMTS12 TRMT9B FER LTBP2 TENM2 ADGRL3

3.51e-04447626EFO_0000694, MONDO_0100096
Diseaseanthropometric measurement

LRIG3 ADAMTS3 LTBP2 TENM2

4.37e-04168624EFO_0004302
Diseasediastolic blood pressure, systolic blood pressure

LRIG3 RIPOR2 AOC1 ADAMTS3 FER GNL2 OR14J1

5.02e-04670627EFO_0006335, EFO_0006336
Diseaseproliferative diabetic retinopathy (is_marker_for)

MAP3K8 ENPP2

5.11e-0416622DOID:13207 (is_marker_for)
Diseaseadvanced glycosylation end product-specific receptor ligand measurement

SLC17A2 OR14J1

8.89e-0421622EFO_0010762
Diseasecoronary artery disease (is_implicated_in)

ACP1 IRS1 CUBN

1.24e-03100623DOID:3393 (is_implicated_in)
Diseaseeyelid sagging measurement

COL13A1 FER

2.07e-0332622EFO_0009360
DiseaseUterine leiomyoma, breast carcinoma

ZBTB46 FAM83F

2.07e-0332622EFO_0000305, HP_0000131

Protein segments in the cluster

PeptideGeneStartEntry
LECPDPQIVGHYMRR

UNC13A

1206

Q9UPW8
PMAVVRRELSCESYP

ADGRL3

26

Q9HAR2
VPDRMCRHNYELGGP

HLA-DPB1

101

P04440
HYPRALCLFEMPTGV

AOC1

411

P19801
MERPKTCGDHPIRFY

DET1

476

Q7L5Y6
MPEEGSGCSVRRRPY

CD70

1

P32970
ENDCEPVGRHPYIMS

ADAMTS12

406

P58397
TRDAGCRPYMAPERI

MAP2K4

261

P45985
GYEECIERPLSPHME

MSANTD2

426

Q6P1R3
TYHRIPMPDFCAPRE

PALD1

621

Q9ULE6
MPKICRLPRHEYGSP

CYFIP1

956

Q7L576
ARDPMGTRSPHIETY

GNL2

226

Q13823
RDIGVPMTSVRLPCY

NMRAL1

141

Q9HBL8
TGCSPDPRTVLMDHY

LRIG3

946

Q6UXM1
EIYMSPEVILCRGHS

MAP3K8

291

P41279
QPLHYETIMDPRACR

OR14J1

126

Q9UGF5
FRCTYRPAMEGPHTV

FLNC

436

Q14315
RMVTHYAVSKGPCRP

KRT82

26

Q9NSB4
CRPTRAVPSSRGDYM

IRS1

976

P35568
RPIHMCRITDSGDPY

PPIL6

296

Q8IXY8
PLRGRYCGTDMPHPI

CUBN

1691

O60494
HSKYCMGDRPESRRP

ADAMTS3

946

O15072
PRMVAIGRYDGTHPC

BBS2

16

Q9BXC9
ISYTCDPHPDRGMTF

CR1

1346

P17927
GYRMSAPQHCPEDIS

FER

776

P16591
ARCRGHPDLSVMYRG

FSTL3

151

O95633
YRTPEGRPDVQMRTC

GALNT4

551

Q8N4A0
PIHRCYARADPTMGR

FSCN3

151

Q9NQT6
MHGAPRLTFPCASEY

CFAP97D2

1

A0A1B0GU71
TGDHAPAPTRMDCYS

LTBP2

1401

Q14767
GPYSSRDPEVLREHM

MANEAL

161

Q5VSG8
APICMEYGRVTLPCR

FZD3

86

Q9NPG1
PMPTCRVYGTVAHQD

KLHDC8B

16

Q8IXV7
IPHGYRDSSPLCMAG

DCBLD2

226

Q96PD2
YPHRECLSSMPAALR

COL13A1

216

Q5TAT6
KLRSCGTHSPYMRPV

ENPP2

191

Q13822
DEIVYPRMPGESTVC

FAM153B

16

P0C7A2
PRMPGESTVCHRERE

FAM153B

21

P0C7A2
GPEYMRCSPHLVLSA

HPX

251

P02790
CFPVPTPEMRSYHFR

TCAF2

401

A6NFQ2
ERRRHPMDSYSPEGN

SLC26A8

951

Q96RN1
MSFVECPYHSPAERL

ING1

1

Q9UK53
RPASCMAFGDPHYRT

KCP

1211

Q6ZWJ8
PDYRGQSCMKRHGIP

ACP1

56

P24666
SYAPHVRICMPLTDG

RXFP2

391

Q8WXD0
GRPMHCQVPGIDYSL

TENM2

1451

Q9NT68
GPDECTMYLSHERGR

ST6GALNAC5

276

Q9BVH7
RCKYSHMEPPLGGLR

TEX45

431

Q8NA69
KYALVSGCRHPPGEM

FAM83F

326

Q8NEG4
CSPVGVYHSPADRVM

RIPOR2

821

Q9Y4F9
IHDQISGMARCPYSP

SEMA5A

151

Q13591
PTCMYRLPNVHGRSY

AIMP2

21

Q13155
GSCRRASVNPMLHEY

CILP

1031

O75339
RYPRGAPAPHCEMSR

TAPBP

81

O15533
IYDDPMHHPCISVRE

SLC17A2

231

O00624
PVSPHECRLRDMTYS

POLR3B

96

Q9NW08
MHSTYDRAGAVPRTP

PIAS4

86

Q8N2W9
RSHSVGYEPAMARTC

TRMT9B

211

Q9P272
HRSCAETGVELMRPY

UBLCP1

151

Q8WVY7
PDRCERMFTAHNGPV

WDR24

196

Q96S15
CRYRHPDMSEVSNLG

ZC3H10

56

Q96K80
RGSDEIFCRVYMPDH

RAPGEFL1

311

Q9UHV5
RSPCHQMSVDYPESE

HIVEP1

2296

P15822
SMRDHIDYRCCLPPA

TOE1

276

Q96GM8
HMRSHTGERPYPCEI

ZBTB46

436

Q86UZ6
MRLFYEPVTTPCGHT

LONRF3

471

Q496Y0