Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmethyl-CpG binding

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

4.97e-0831655GO:0008327
GeneOntologyBiologicalProcessDNA methylation-dependent constitutive heterochromatin formation

MBD3L5 MBD3L2 ATF7IP2 MBD3L3 MBD3L4 MBD3L2B

4.97e-0944656GO:0006346
GeneOntologyBiologicalProcessfacultative heterochromatin formation

MBD3L5 MBD3L2 ATF7IP2 MBD3L3 MBD3L4 MBD3L2B

1.99e-0855656GO:0140718
GeneOntologyBiologicalProcessheterochromatin formation

MBD3L5 MBD3L2 ATF7IP2 MBD3L3 MBD3L4 MBD3L2B

1.25e-05163656GO:0031507
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

MBD3L5 MBD3L2 ATF7IP2 MBD3L3 MBD3L4 MBD3L2B

4.30e-05203656GO:0045814
DomainMeCpG-bd_2/3_C_dom

MBD3L5 MBD3L2 MBD3L3 MBD3L4

4.08e-097634IPR025884
DomainMBD2/MBD3_p55-bd

MBD3L5 MBD3L2 MBD3L3 MBD3L4

4.08e-097634IPR032343
DomainMBD_C

MBD3L5 MBD3L2 MBD3L3 MBD3L4

4.08e-097634PF14048
DomainMBDa

MBD3L5 MBD3L2 MBD3L3 MBD3L4

4.08e-097634PF16564
DomainRad21/Rec8_C_eu

RAD21L1 RAD21

3.35e-053632IPR006909
DomainRad21_Rec8_N

RAD21L1 RAD21

3.35e-053632IPR006910
Domain-

RAD21L1 RAD21

3.35e-0536321.10.10.580
DomainRad21_Rec8_N

RAD21L1 RAD21

3.35e-053632PF04825
DomainRad21_Rec8

RAD21L1 RAD21

3.35e-053632PF04824
DomainRad21/Rec8_C

RAD21L1 RAD21

3.35e-053632IPR023093
DomainActinin_actin-bd_CS

SPTBN5 MACF1

2.71e-0323632IPR001589
DomainSpectrin

SPTBN5 MACF1

2.71e-0323632PF00435
DomainACTININ_2

SPTBN5 MACF1

2.71e-0323632PS00020
DomainACTININ_1

SPTBN5 MACF1

2.71e-0323632PS00019
DomainSpectrin_repeat

SPTBN5 MACF1

4.29e-0329632IPR002017
DomainFN3

IGF1R FNDC11 ATF7IP2 SORL1

4.56e-03199634PS50853
DomainSpectrin/alpha-actinin

SPTBN5 MACF1

5.20e-0332632IPR018159
DomainSPEC

SPTBN5 MACF1

5.20e-0332632SM00150
DomainFN3_dom

IGF1R FNDC11 ATF7IP2 SORL1

5.42e-03209634IPR003961
Pubmed

MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

1.26e-13666512504854
Pubmed

Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

1.26e-13666518942147
Pubmed

MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

6.24e-111566515701600
Pubmed

Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer.

IGF1R ESR1

3.55e-06266215595626
Pubmed

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.

IGF1R ROR1

3.55e-06266226173023
Pubmed

Estrogen receptor alpha (ERalpha) and insulin-like growth factor I receptor (IGF-IR) cross-talk in the gonadotropic alphaT3-1 cell line.

IGF1R ESR1

3.55e-06266217458895
Pubmed

IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules.

IGF1R ESR1

3.55e-06266228079144
Pubmed

A low concentration of genistein induces estrogen receptor-alpha and insulin-like growth factor-I receptor interactions and proliferation in uterine leiomyoma cells.

IGF1R ESR1

3.55e-06266218492705
Pubmed

The crosstalk between IGF-1R and ER-α in the proliferation and anti-inflammation of nucleus pulposus cells.

IGF1R ESR1

3.55e-06266232572901
Pubmed

Anticancer effect of genistein on BG-1 ovarian cancer growth induced by 17 β-estradiol or bisphenol A via the suppression of the crosstalk between estrogen receptor α and insulin-like growth factor-1 receptor signaling pathways.

IGF1R ESR1

3.55e-06266223933164
Pubmed

Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.

NALCN UNC79

1.06e-05366226708753
Pubmed

Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).

NALCN UNC79

1.06e-05366230167850
Pubmed

PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth.

IGF1R ESR1

1.06e-05366223821363
Pubmed

Interaction between IGF-IR and ER induced by E2 and IGF-I.

IGF1R ESR1

1.06e-05366223704881
Pubmed

The WT1 Wilms' tumor suppressor gene product interacts with estrogen receptor-alpha and regulates IGF-I receptor gene transcription in breast cancer cells.

IGF1R ESR1

1.06e-05366216087727
Pubmed

Estrogen receptor α L429 and A430 regulate 17β-estradiol-induced cell proliferation via CREB1.

IGF1R ESR1

1.06e-05366226348925
Pubmed

Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells.

IGF1R ESR1

1.06e-05366228498399
Pubmed

Expression of the insulin-like growth factor-I receptor in primary breast cancer and lymph node metastases: correlations with estrogen receptors alpha and beta.

IGF1R ESR1

1.06e-05366214710360
Pubmed

The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane.

IGF1R ESR1

1.06e-05366214764897
Pubmed

Long-term estradiol deprivation in breast cancer cells up-regulates growth factor signaling and enhances estrogen sensitivity.

IGF1R ESR1

1.06e-05366216113100
Pubmed

Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.

NALCN UNC79

1.06e-05366221040849
Pubmed

Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.

NALCN UNC79

1.06e-05366232620897
Pubmed

Poly(ADP-ribose) polymerase as a novel regulator of 17β-estradiol-induced cell growth through a control of the estrogen receptor/IGF-1 receptor/PDZK1 axis.

IGF1R ESR1

2.12e-05466226183824
Pubmed

Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway.

IGF1R ESR1

2.12e-05466210749889
Pubmed

Estrogen receptor alpha inhibits RLR-mediated immune response via ubiquitinating TRAF3.

TRAF3 ESR1

2.12e-05466226186972
Pubmed

Insulin-like growth factor-1 promotes wound healing in estrogen-deprived mice: new insights into cutaneous IGF-1R/ERα cross talk.

IGF1R ESR1

2.12e-05466222810305
Pubmed

The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.

NALCN UNC79

2.12e-05466232494638
Pubmed

Insulin-like growth factor-2 (IGF-2) activates estrogen receptor-α and -β via the IGF-1 and the insulin receptors in breast cancer cells.

IGF1R ESR1

3.53e-05566221410323
Pubmed

Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling.

IGF1R ESR1

5.29e-05666220042609
Pubmed

A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells.

IGF1R ESR1

9.86e-05866228555617
Pubmed

Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.

IGF1R ESR1

1.27e-04966217662267
Pubmed

The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility.

RAD21L1 RAD21

1.27e-04966221743440
Pubmed

Genome-wide association study (GWAS) for molar-incisor hypomineralization (MIH).

TTLL12 RMI1

1.27e-04966223918034
Pubmed

Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.

IGF1R ESR1 PARG STAT6

1.53e-0414166418636124
Pubmed

RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis.

RAD21L1 RAD21

1.58e-041066221242291
Pubmed

Proteomic identification of Profilin1 as a corepressor of estrogen receptor alpha in MCF7 breast cancer cells.

ESR1 CEP290

1.58e-041066223576398
Pubmed

Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.

IGF1R ESR1

1.58e-041066224051437
Pubmed

Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription.

ESR1 CNOT2

1.58e-041066216778766
Pubmed

Meiotic cohesin complexes are essential for the formation of the axial element in mice.

RAD21L1 RAD21

2.31e-041266222711701
Pubmed

A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.

RAD21L1 RAD21

2.31e-041266221274006
Pubmed

The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3.

ESR1 STAT6

3.18e-041466222588720
Pubmed

A unique role of cohesin-SA1 in gene regulation and development.

RAD21L1 RAD21

4.18e-041666222415368
Pubmed

Exploration of 16 candidate genes identifies the association of IDE with Alzheimer's disease in Han Chinese.

ESR1 SORL1

4.18e-041666220880607
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TTLL12 MXRA5 ROR1 CEP290 PPP6R1 CTPS1 PIGM

4.87e-0473666729676528
Pubmed

Liganded ERα Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation.

SASH1 ESR1

5.94e-041966226389696
Pubmed

STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis.

RAD21L1 RAD21

6.59e-042066224797475
Pubmed

Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth.

TRAF3 IGF1R

7.99e-042266227798115
Pubmed

Meiosis in mice without a synaptonemal complex.

RAD21L1 RAD21

7.99e-042266222164254
Pubmed

TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development.

TSHZ2 TBX2

8.75e-042366238828908
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ZC3H7A RMI1 MACF1 PPP6R1 PLRG1 SORL1

8.76e-0458866638580884
Pubmed

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

IGF1R ESR1

1.03e-032566218992263
Pubmed

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.

DCDC1 ESR1

1.21e-032766219801982
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

IGF1R ESR1 ROR1 ATF7IP2 SPAG8

1.22e-0342066528065597
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CCDC117 TTLL12 PTPN23 CTPS1 PLRG1 RAD21

1.33e-0363866633239621
Pubmed

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.

PLRG1 DHX8

1.49e-033066228076346
Cytoband19p13.2

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

2.06e-0522966519p13.2
Cytoband1p32-p31

ROR1 MACF1

7.28e-0596621p32-p31
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CCDC117 SASH1 HMCN1 NALCN TSHZ2 ESR1 ROR1

1.08e-0818466767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADCY4 SASH1 HMCN1 NALCN TSHZ2 STON2

3.86e-071906666e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 NALCN TSHZ2 KIF26A CHST1

8.34e-061866659579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell3'_v3-blood|World / Manually curated celltypes from each tissue

TRABD2A NACC2 TSHZ2 ATF7IP2 SORL1

8.55e-061876659e70e8d7cd8ae517ddf5fd56c69ec16fc33ddff5
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

HMCN1 NALCN TSHZ2 ROR1 TBX2

9.97e-06193665e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 SASH1 HMCN1 ATP13A2 PRX

1.02e-05194665f159ef8541d75a4e98468947f231bb463bec922c
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 SASH1 NALCN TSHZ2 STON2

1.02e-05194665937ee85ffd50869b60f0f6e91017ab77e8b24c0b
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STON2 CHST1 ATP13A2 PRX TBX2

1.05e-05195665cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCellIPF-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

MXRA5 HMCN1 TSHZ2 ROR1 TBX2

1.07e-051966657fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCellIPF-Stromal-Myofibroblast|IPF / Disease state, Lineage and Cell class

MXRA5 HMCN1 TSHZ2 ROR1 TBX2

1.07e-051966652d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 SASH1 NALCN TSHZ2 STON2

1.10e-05197665407231542fa1ffd540dcb61435c0575e71f59725
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 SASH1 NALCN TSHZ2 STON2

1.13e-051986655d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCellIPF-Stromal|IPF / Disease state, Lineage and Cell class

MXRA5 HMCN1 TSHZ2 ROR1 TBX2

1.13e-05198665ece914c32c9b123b779aa9624b92e6230763a20e
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 SASH1 NALCN TSHZ2 STON2

1.13e-0519866599d6a64f3410dae3019161feef20a8f06081a24b
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL12 SELENBP1 TSHZ2 ATP5MJ

8.69e-05157664a93866f051472506f1468f379c0d5313e02c9731
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC117 PARG CSMD3 PRX

8.91e-051586646d2709b387945c015faa223c20d22b52a4082140
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L5_RORB_SNHG7|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRABD2A TSHZ2 ESR1 STAT6

9.81e-05162664daacccf8b1374680803f49135673a00e09691cde
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

HMCN1 NALCN TSHZ2 TBX2

1.10e-04167664d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NALCN TSHZ2 ESR1 RAD21L1

1.13e-04168664d19a115365c5415e51c039718d7669de788fcf33
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NALCN CSMD3 DNAH5 UNC79

1.15e-0416966412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 FNDC11 SPAG8 DNAH5

1.26e-04173664c3762655caa79ac4879876f470d32578a3c93b01
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SASH1 NALCN TSHZ2 STON2

1.26e-041736647dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ADCY4 TRAF3 KIF26A PRX

1.29e-04174664b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMCN1 NALCN MACF1 TBX2

1.32e-041756641799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

TRABD2A TSHZ2 ATF7IP2 SORL1

1.32e-041756644b77e9cf712c9e3b4fb68462a96aea47be124e8d
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

ADCY4 SASH1 TSHZ2 STON2

1.35e-0417666498c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

ADCY4 SASH1 TSHZ2 STON2

1.35e-04176664c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4|GI_large-bowel / Manually curated celltypes from each tissue

TRABD2A UXS1 IGF1R TSHZ2

1.38e-04177664eb87ea93e36a8f97442ec8515f658ee61932dc0f
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 SASH1 TSHZ2 STON2

1.38e-04177664b1775e05c28883a15c56628028770bc59d3233fb
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 KIF26A UNC79 PRX

1.41e-04178664804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4V2 GINS2 SPAG8 DNAH5

1.41e-041786646178706db4a855d72abc156537604d575624df56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4V2 GINS2 SPAG8 DNAH5

1.41e-04178664f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 KIF26A UNC79 PRX

1.41e-04178664ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A TSHZ2 ATP6V0A4 SORL1

1.47e-04180664f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

SASH1 TSHZ2 PRX TBX2

1.50e-0418166461608123959483ff60f07d8467996853c4371b6a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBD3L5 NACC2 KLHDC8A MAP3K20

1.50e-041816647704f236831cffe4f2a75d4c461eb88b4177e206
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V0A4 CHST1 PRX TBX2

1.50e-04181664cd81bc307e2bc42c1e9b24d5645ab65fa18c6133
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 FNDC11 SPAG8 DNAH5

1.54e-04182664e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY4 TRAF3 HMCN1 FNDC11

1.54e-04182664f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY4 NALCN TSHZ2 STON2

1.57e-04183664bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A IGF1R TSHZ2 SORL1

1.57e-04183664f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 CSMD3 DNAH5 UNC79

1.60e-041846642cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 CSMD3 DNAH5 UNC79

1.60e-04184664ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 CSMD3 DNAH5 UNC79

1.60e-041846642b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A IGF1R TSHZ2 SORL1

1.60e-041846645350b58aa9979631228835d11eb45ddf81d08bff
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

SASH1 TSHZ2 PRX TBX2

1.60e-041846645f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ADCY4 SASH1 TSHZ2 STON2

1.63e-041856644a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

ZC3H7A TRAF3 UXS1 TSHZ2

1.63e-04185664e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ADCY4 SASH1 TSHZ2 STON2

1.63e-0418566436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellP28-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHST1 ATP13A2 PRX TBX2

1.67e-04186664375642f353842184792a834361284d6897c728de
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

ADCY4 SASH1 PRX TBX2

1.67e-04186664c6075fe84226b370c5139066793844ad33ae2db1
ToppCellP28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADCY4 HMCN1 TSHZ2 CTPS1

1.67e-04186664153c8b2fd8a6e2141ca97c626f82e5f081f3180a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A IGF1R TSHZ2 SORL1

1.67e-04186664c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|343B / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 SASH1 TSHZ2 STON2

1.67e-041866647a8da2ad140bea3207bd868212cc5e201d586772
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 SASH1 TSHZ2 STON2

1.67e-04186664dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCellAdult-Endothelial-endothelial_cell_of_artery|Adult / Lineage, Cell type, age group and donor

TRABD2A ADCY4 HMCN1 KIF26A

1.67e-041866642d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCellP15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHST1 ATP13A2 PRX TBX2

1.70e-0418766460f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCellP15-Endothelial-unknown_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHST1 ATP13A2 PRX TBX2

1.70e-04187664d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

HMCN1 NALCN TSHZ2 TBX2

1.70e-04187664bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellP03-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHST1 ATP13A2 PRX TBX2

1.70e-0418766455618ceec367c1c51ed5c447063d7fbd5c7e0808
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

ADCY4 NALCN TSHZ2 STON2

1.74e-0418866480910dcbb51990f2baed240f319456c0d3fa2065
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 TSHZ2 DNAH5 TBX2

1.74e-04188664997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellP15-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHST1 ATP13A2 PRX TBX2

1.74e-04188664c0a03e33027f52b5c25ffbc8f822128e5160ed20
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A IGF1R TSHZ2 SORL1

1.77e-041896649ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellIPF-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

ZC3H7A TRAF3 UXS1 TSHZ2

1.77e-041896647a260485c2a7c743c14d048e5e480ae0a9b8e32c
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST1 ATP13A2 PRX TBX2

1.77e-0418966409dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 CHST1 PRX TBX2

1.77e-041896647b6cb745c0a637d6addc105a79059ed488fced39
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A IGF1R TSHZ2 SORL1

1.77e-041896645a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SELENBP1 HMCN1 MAP3K20 MACF1

1.77e-04189664dc5164591dea45b420798b94dda211be03daa70c
ToppCelldroplet-Lung-LUNG-30m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 SASH1 HMCN1 PRX

1.77e-0418966425db316f66cee53774bb2b286cc457b37353356c
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY4 NALCN TSHZ2 STON2

1.77e-0418966455a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHST1 ATP13A2 PRX TBX2

1.81e-0419066452213cd2a6a20772d4f49ba9ac0407abafa528db
ToppCellP07-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHST1 ATP13A2 PRX TBX2

1.81e-041906645d25e40bc2cca314f4265e4001a546e6d99e2a79
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TSHZ2 ROR1 MAP3K20 TBX2

1.81e-04190664d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SELENBP1 HMCN1 MAP3K20 MACF1

1.81e-041906641196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 NALCN ROR1 MAP3K20

1.81e-04190664562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

IGF1R SASH1 PRX TBX2

1.81e-041906640e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

HMCN1 MACF1 TBX2 SORL1

1.81e-0419066471e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 NALCN ROR1 MAP3K20

1.81e-04190664f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 SASH1 HMCN1 PRX

1.81e-04190664e64b191f928935484e2c993d7f8af0572a617a3a
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STON2 CHST1 PRX TBX2

1.85e-04191664df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A IGF1R TSHZ2 SORL1

1.85e-04191664d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SELENBP1 MAP3K20 MACF1 TBX2

1.85e-04191664e7c605b56934d1383237c1f946dbccef25d91368
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY4 CHST1 PRX TBX2

1.85e-04191664718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY4 CHST1 PRX TBX2

1.85e-04191664454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADCY4 SASH1 HMCN1 KIF26A

1.85e-04191664dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellIPF-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

TRABD2A IGF1R HMCN1 ROR1

1.88e-04192664e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ENOSF1 TSHZ2 MACF1 SORL1

1.88e-0419266447646d7e4990be85072987f92bf18d52f8da752e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DCDC1 SELENBP1 SPAG8 DNAH5

1.88e-0419266403acd4a26b986e34eee608747347791122f1aa52
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STON2 CHST1 PRX TBX2

1.88e-0419266435f7926628a967f85b26371e795a1b93c6f103ab
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DCDC1 SELENBP1 SPAG8 DNAH5

1.88e-0419266431c6046589e2fbb0486fd044c5b128099d37872f
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DCDC1 TSHZ2 SPAG8 DNAH5

1.92e-04193664ea345d34440b25f65358a53dc72831998d1c3620
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRABD2A IGF1R TSHZ2 SORL1

1.92e-041936644e78ddc96d8e403a21c4a303b1f26512d2ac91e8
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SASH1 NALCN TSHZ2 STON2

1.92e-04193664bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATP6V0A4 CHST1 PRX TBX2

1.92e-0419366425129080f8a40b2988a5d9dfec36ff9e72c27e61
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

TRABD2A IGF1R TSHZ2 SORL1

1.92e-04193664772e0370bda4bffed7798b8714e32c9e2a1d9b67
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

HMCN1 NALCN MACF1 TBX2

1.92e-041936645896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HMCN1 TSHZ2 CSMD3 TBX2

1.96e-04194664011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

MXRA5 HMCN1 NALCN TSHZ2

1.96e-0419466403a269f75a481ea54aea8e6444605db8d6df493d
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SELENBP1 MAP3K20 MACF1 TBX2

1.96e-041946644f9bd0ded0dde1df885850714f29e73e992539a5
DrugCimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A

TRAF3 SLC22A14 ESR1 CEP290 MINDY2 SORL1

1.71e-051936461464_DN
DrugBicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A

TRAF3 SLC22A14 ESR1 MAP3K20 MACF1 STAT6

1.98e-051986464397_DN
DrugFipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; HL60; HG-U133A

ENOSF1 TRAF3 MACF1 MINDY2 DHX8 RAD21

1.98e-051986461560_DN
DrugLinseed Oil

IGF1R ESR1 STAT6

1.99e-0519643ctd:D008043
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

RMI1 TRAF3 IGF1R DCDC1 TSHZ2 KIF26A ESR1 MAP3K20 UNC79 SORL1

4.54e-068016010EFO_0003888, EFO_0007052, MONDO_0002491
Diseaseasparagine measurement, amino acid measurement

KIF26A ATP5MJ

2.43e-054602EFO_0005134, EFO_0009766
Diseasemolar-incisor hypomineralization

TTLL12 RMI1

1.45e-049602EFO_0005321
Diseaseaortic measurement

DCDC1 SASH1 HMCN1 ESR1 STAT6

1.60e-04251605EFO_0020865
Diseasecryptorchidism (biomarker_via_orthology)

IGF1R ESR1

2.21e-0411602DOID:11383 (biomarker_via_orthology)
Diseasediet measurement

RMI1 NALCN ESR1 KLHDC8A STON2 ATP5MJ MINDY2 DNAH5 SORL1

2.54e-041049609EFO_0008111
Diseasetaurolithocholate 3-sulfate measurement

IGF1R ESR1

3.13e-0413602EFO_0021036
Diseasebody surface area

TRAF3 IGF1R ESR1 MACF1 CTPS1 ATP13A2 UNC79

3.21e-04643607EFO_0022196
DiseaseEndometrial Carcinoma

IGF1R ESR1 RAD21

4.31e-0472603C0476089
Diseasethyroid volume

IGF1R DNAH5

4.79e-0416602EFO_0004865
Diseaseselenium measurement, response to dietary selenium supplementation

ZC3H7A DNAH5

7.55e-0420602EFO_0006331, EFO_0600021
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

TSHZ2 STON2 CSMD3

7.76e-0488603EFO_0803332
Diseaserisk-taking behaviour

RMI1 IGF1R DCDC1 TSHZ2 KIF26A UNC79 SORL1

8.90e-04764607EFO_0008579
DiseaseCarcinoma of lung

MXRA5 RAD21

1.00e-0323602C0684249
Diseasetestosterone measurement

ZC3H7A RMI1 DCDC1 HMCN1 TSHZ2 ESR1 MACF1 CTPS1 CSMD3

1.04e-031275609EFO_0004908
Diseasesuicidal ideation, suicide behaviour

TRAF3 ESR1

1.09e-0324602EFO_0004320, EFO_0007623
Diseasesmoking behaviour measurement

RMI1 IGF1R SASH1 MAP3K20

1.09e-03222604EFO_0005671
DiseaseFamilial Alzheimer Disease (FAD)

IGF1R ESR1 SORL1

1.12e-03100603C0276496
DiseaseAlzheimer's Disease

IGF1R ESR1 SORL1

1.16e-03101603C0002395
Diseasesexual dimorphism measurement

SPTBN5 ADCY4 IGF1R ESR1 PTPN23 MACF1 CTPS1 ATP13A2

1.73e-031106608EFO_0021796
Diseaseosteoporosis (is_implicated_in)

IGF1R ESR1

1.82e-0331602DOID:11476 (is_implicated_in)
Diseasemigraine disorder, glucose measurement

RMI1 IGF1R

1.82e-0331602EFO_0004468, MONDO_0005277
Diseasesleep duration, high density lipoprotein cholesterol measurement

ATP6V0A4 MACF1 DHX8

1.94e-03121603EFO_0004612, EFO_0005271

Protein segments in the cluster

PeptideGeneStartEntry
KKAKLMLGWEPVVPL

UXS1

366

Q8NBZ7
MSRPSMELVLWKPLP

CCDC117

201

Q8IWD4
ILMDGKVMWSGLIPK

CSMD3

876

Q7Z407
MRCVLKGPKMLHWLP

ADCY4

636

Q8NFM4
ELAPPTQRLMMWKKR

RAD21L1

326

Q9H4I0
LDLAPPTKKLMMWKE

RAD21

351

O60216
MEAVPRMPMIWLDLK

PTPN23

1

Q9H3S7
LIKKVTWTMNGLMLP

DCDC1

256

M0R2J8
MLRHLPSRLPVKMWG

GLOD5

1

A6NK44
GKPVWKLLVDMDPRM

ENOSF1

131

Q7L5Y1
KGLLPVRWMSPESLK

IGF1R

1171

P08069
SPPVLGKLKRNMMPW

MBD3L5

11

A6NJ08
ALMAKKAPTMPKPQW

PLRG1

176

O43660
MRAANLWPSPLMIKR

ESR1

286

P03372
KKWLGTPIEEMRRMP

PARG

451

Q86W56
SLPVLGKLKRNMMPW

MBD3L2B

11

A0A1B0GVZ6
PGSIGKVKVMLRIWP

KIF26A

366

Q9ULI4
PWLMEKELMMGVLGP

MACF1

4591

Q9UPN3
SPPVLGKLKRNMMPW

MBD3L3

11

A6NE82
IASGIPAPKMTWMKD

HMCN1

3551

Q96RW7
MMAGIPLLLFRWKPL

ATP13A2

56

Q9NQ11
KRQLEIWMEMAPSKP

LINC01599

16

Q8WXQ3
MPPNINWKEIMKVDP

CEP290

1

O15078
KIPHIWLMLSTKMPV

FNDC11

196

Q9BVV2
HMPLLKLWVGPVPMV

CYP4V2

86

Q6ZWL3
WKKIGEIKALPLPMA

ATF7IP2

626

Q5U623
EILKMTKPPFVMEKW

MAP3K20

486

Q9NYL2
LKDMWVSLAPMPTPR

KLHDC8A

151

Q8IYD2
VVGPPMAKQWLLLMF

KHDC1L

71

Q5JSQ8
MLQSIIKNIWIPMKP

ATP5MJ

1

P56378
ILPESPRWLMMKGKV

SLC22A14

316

Q9Y267
RGIGMMPNDIPEWKK

DHX8

526

Q14562
RRLWQMTKIKMLPTP

DNAH5

2771

Q8TE73
SPPVLGKLKRNMMPW

MBD3L4

11

A6NDZ8
SLPVLGKLKRNMMPW

MBD3L2

11

Q8NHZ7
LLAWKVKLPPMMEII

MINDY2

276

Q8NBR6
VTLTWMRPKKMPSAS

SORL1

1571

Q92673
RGLWKPPDIKGKLMV

SPAG8

256

Q99932
PWEAKPSRMLMLQLT

RMI1

126

Q9H9A7
LPPEWMDVEKLEKMR

GINS2

61

Q9Y248
DLPIERQPRKMLMKW

CTPS1

271

P17812
KKVKGWLLPEMPGLI

SELENBP1

296

Q13228
DPLAPMEPLLWKHKM

SPTBN5

2606

Q9NRC6
DGWPMMLRIPEKKNI

STON2

426

Q8WXE9
GLMRPPWLKGKYMLV

CHST1

286

O43916
RVWITRAPGMEPTMK

CNOT2

476

Q9NZN8
KSLLPIRWMPPEAIM

ROR1

651

Q01973
MKMSIWTPPRLLELA

PRAMEF4

1

O60810
LPWPFKQKVTLMLMD

TRAF3

486

Q13114
RWMVAGKADPEMPKR

TBX2

171

Q13207
MSLWGLVSKMPPEKV

STAT6

1

P42226
GWDGRVKMPKLKMPS

PRX

1051

Q9BXM0
EPWNMKRHKMVAKPP

ZNF723

61

P0DPD5
DIIDIISKPPMGTWM

SASH1

581

O94885
KLMMPLWMTPDQRGK

TRABD2A

131

Q86V40
IRKCMLLPWAPTDML

TTLL12

251

Q14166
RPIAPKWKVMPLVSM

TSHZ2

576

Q9NRE2
KLEPLQMTWGMLAPP

PPP6R1

336

Q9UPN7
MALISVPWMLLIKPF

ATP6V0A4

646

Q9HBG4
WMNIRPLPTKKQMPL

ZC3H7A

756

Q8IWR0
LIATMRSKPWPMAKK

TMC2

166

Q8TDI7
VMPLVRMPWKRAVVL

PIGM

346

Q9H3S5
TIFVKLIPMWLPMIQ

UNC79

2551

Q9P2D8
MSPWGMLRIPRPLIM

NALCN

136

Q8IZF0
MAMGIPKADITWELP

MXRA5

2756

Q9NR99
WLPKIKSMLPEGVEM

NACC2

451

Q96BF6