Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF7 KLF11 KLF16 KAT2B ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 NFX1 KLF14 WT1 ZNF267 ZNF396 ZNF417 SMYD3 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	7.81e-08	1459	83	22	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF396 ZNF417 SMYD3 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	6.06e-07	1244	83	19	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF396 ZNF417 SMYD3 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	8.39e-07	1271	83	19	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 NFX1 KLF14 WT1 ZNF267 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	9.44e-07	1412	83	20	GO:0000981
GeneOntologyMolecularFunction	methylated histone binding	EED ING1 KDM5A ING5 MORC3	2.94e-05	86	83	5	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	EED ING1 KDM5A ING5 MORC3	3.28e-05	88	83	5	GO:0140034
GeneOntologyMolecularFunction	transforming growth factor beta binding	THBS1 WFIKKN2 LTBP1	1.68e-04	26	83	3	GO:0050431
GeneOntologyMolecularFunction	modification-dependent protein binding	EED ING1 KDM5A ING5 MPND MORC3	2.19e-04	206	83	6	GO:0140030
GeneOntologyMolecularFunction	double-stranded methylated DNA binding	WT1 ZNF445	3.54e-04	7	83	2	GO:0010385
GeneOntologyMolecularFunction	heparan sulfate binding	PTN MDK	6.03e-04	9	83	2	GO:1904399
GeneOntologyMolecularFunction	histone binding	EED ING1 KDM5A ING5 NAP1L4 MORC3	8.30e-04	265	83	6	GO:0042393
GeneOntologyMolecularFunction	chondroitin sulfate binding	PTN MDK	9.16e-04	11	83	2	GO:0035374
GeneOntologyMolecularFunction	chromatin binding	KAT2B EED KDM5A ING5 KLF14 NAP1L4 POLQ NUP153 ZIC2 ZNF445	9.63e-04	739	83	10	GO:0003682
GeneOntologyMolecularFunction	proteoglycan binding	CFH PTN THBS1	1.25e-03	51	83	3	GO:0043394
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP12 LRP1B	1.97e-03	16	83	2	GO:0005041
GeneOntologyBiologicalProcess	leukocyte migration involved in inflammatory response	SLAMF8 PTN MDK ADAM8	2.94e-06	26	80	4	GO:0002523
GeneOntologyBiologicalProcess	leukocyte chemotaxis involved in inflammatory response	SLAMF8 PTN MDK	3.10e-06	8	80	3	GO:0002232
GeneOntologyBiologicalProcess	leukocyte aggregation	CFH THBS1 ADAM8	5.21e-05	19	80	3	GO:0070486
GeneOntologyBiologicalProcess	negative regulation of cell population proliferation	PTN SLFN12L KLF11 THBS1 KAT2B ING1 CLEC4G ING5 WT1 XDH MORC3 DLL1 FOXP3	7.80e-05	961	80	13	GO:0008285
GeneOntologyBiologicalProcess	regulation of neutrophil migration	SLAMF8 MDK ADAM8 EDN1	8.12e-05	59	80	4	GO:1902622
Domain	Znf_C2H2/integrase_DNA-bd	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	9.26e-11	694	81	19	IPR013087
Domain	Znf_C2H2-like	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF622 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	1.24e-10	796	81	20	IPR015880
Domain	Znf_C2H2	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF622 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	1.52e-10	805	81	20	IPR007087
Domain	ZnF_C2H2	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF622 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	1.62e-10	808	81	20	SM00355
Domain	-	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 WT1 ZNF267 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	5.27e-10	679	81	18	3.30.160.60
Domain	ZINC_FINGER_C2H2_2	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	5.95e-10	775	81	19	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445 FOXP3	6.21e-10	777	81	19	PS00028
Domain	zf-C2H2	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445	7.31e-10	693	81	18	PF00096
Domain	EGF_CA	THBS1 EGF C1S HABP2 LTBP1 DLL1 LRP1B CRB1	5.68e-08	122	81	8	SM00179
Domain	EGF-like_Ca-bd_dom	THBS1 EGF C1S HABP2 LTBP1 DLL1 LRP1B CRB1	6.45e-08	124	81	8	IPR001881
Domain	EGF-like_dom	THBS1 EGF LAMB1 C1S HABP2 LTBP1 DLL1 ADAM8 LRP1B CRB1	1.21e-07	249	81	10	IPR000742
Domain	EGF_1	THBS1 EGF LAMB1 C1S HABP2 LTBP1 DLL1 ADAM8 LRP1B CRB1	1.51e-07	255	81	10	PS00022
Domain	EGF-like_CS	THBS1 EGF LAMB1 C1S HABP2 LTBP1 DLL1 ADAM8 LRP1B CRB1	1.88e-07	261	81	10	IPR013032
Domain	EGF_2	THBS1 EGF LAMB1 C1S HABP2 LTBP1 DLL1 ADAM8 LRP1B CRB1	2.16e-07	265	81	10	PS01186
Domain	EGF_3	THBS1 EGF C1S HABP2 LTBP1 DLL1 ADAM8 LRP1B CRB1	8.05e-07	235	81	9	PS50026
Domain	EGF	THBS1 EGF LAMB1 HABP2 LTBP1 DLL1 ADAM8 LRP1B CRB1	8.05e-07	235	81	9	SM00181
Domain	EGF	EGF C1S HABP2 LTBP1 DLL1 LRP1B CRB1	1.24e-06	126	81	7	PF00008
Domain	KRAB	ZNF7 ZNF605 ZNF337 ZNF587 ZNF283 ZNF267 ZNF417 ZNF829 ZNF331 ZNF445	3.31e-06	358	81	10	PS50805
Domain	KRAB	ZNF7 ZNF605 ZNF337 ZNF587 ZNF283 ZNF267 ZNF417 ZNF829 ZNF331 ZNF445	3.31e-06	358	81	10	PF01352
Domain	EGF_Ca-bd_CS	EGF C1S LTBP1 DLL1 LRP1B CRB1	3.98e-06	97	81	6	IPR018097
Domain	KRAB	ZNF7 ZNF605 ZNF337 ZNF587 ZNF283 ZNF267 ZNF417 ZNF829 ZNF331 ZNF445	4.33e-06	369	81	10	SM00349
Domain	KRAB	ZNF7 ZNF605 ZNF337 ZNF587 ZNF283 ZNF267 ZNF417 ZNF829 ZNF331 ZNF445	4.44e-06	370	81	10	IPR001909
Domain	EGF_CA	EGF C1S LTBP1 DLL1 LRP1B CRB1	4.48e-06	99	81	6	PS01187
Domain	ASX_HYDROXYL	EGF C1S LTBP1 DLL1 LRP1B CRB1	4.75e-06	100	81	6	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	EGF C1S LTBP1 DLL1 LRP1B CRB1	6.66e-06	106	81	6	IPR000152
Domain	PTN/MK_C_dom	PTN MDK	1.86e-05	2	81	2	IPR020090
Domain	PTN/MK_diS	PTN MDK	1.86e-05	2	81	2	IPR020091
Domain	PTN_MK_heparin-bd_GF_CS	PTN MDK	1.86e-05	2	81	2	IPR020092
Domain	PTN/MK_N_dom	PTN MDK	1.86e-05	2	81	2	IPR020089
Domain	-	PTN MDK	1.86e-05	2	81	2	2.30.90.10
Domain	PTN_MK_N	PTN MDK	1.86e-05	2	81	2	PF05196
Domain	Midkine_heparin-bd_GF	PTN MDK	1.86e-05	2	81	2	IPR000762
Domain	PTN_MK_2	PTN MDK	1.86e-05	2	81	2	PS00620
Domain	PTN_MK_1	PTN MDK	1.86e-05	2	81	2	PS00619
Domain	PTN_MK_hepar_bd	PTN MDK	1.86e-05	2	81	2	PD005592
Domain	PTN	PTN MDK	1.86e-05	2	81	2	SM00193
Domain	-	PTN MDK	1.86e-05	2	81	2	2.20.60.10
Domain	PTN_MK_C	PTN MDK	1.86e-05	2	81	2	PF01091
Domain	Znf_PHD-finger	ING1 KDM5A NFX1 ING5 PHF21B	2.37e-05	79	81	5	IPR019787
Domain	EGF_CA	THBS1 EGF C1S LTBP1 LRP1B	3.58e-05	86	81	5	PF07645
Domain	Growth_fac_rcpt_	EGF LAMB1 LTBP1 DLL1 LRP1B CRB1	5.97e-05	156	81	6	IPR009030
Domain	Zinc_finger_PHD-type_CS	ING1 KDM5A NFX1 ING5	1.82e-04	65	81	4	IPR019786
Domain	ING	ING1 ING5	1.84e-04	5	81	2	SM01408
Domain	ING_N_histone_binding	ING1 ING5	1.84e-04	5	81	2	IPR024610
Domain	ING	ING1 ING5	1.84e-04	5	81	2	PF12998
Domain	ING_fam	ING1 ING5	1.84e-04	5	81	2	IPR028651
Domain	PHD	ING1 KDM5A ING5 PHF21B	3.16e-04	75	81	4	PF00628
Domain	zf-C2H2_6	ZNF605 ZNF587 ZNF283 ZNF267 ZNF417 ZNF331 ZNF445	4.26e-04	314	81	7	PF13912
Domain	PHD	ING1 KDM5A ING5 PHF21B	6.06e-04	89	81	4	SM00249
Domain	Znf_PHD	ING1 KDM5A ING5 PHF21B	6.59e-04	91	81	4	IPR001965
Domain	ZF_PHD_2	ING1 KDM5A ING5 PHF21B	7.75e-04	95	81	4	PS50016
Domain	ZF_PHD_1	ING1 KDM5A ING5 PHF21B	8.06e-04	96	81	4	PS01359
Domain	C-type_lectin_CS	MRC2 CD207 CLEC4G	8.56e-04	43	81	3	IPR018378
Domain	Ldl_recept_b	EGF LRP1B	1.63e-03	14	81	2	PF00058
Domain	LDLRB	EGF LRP1B	1.63e-03	14	81	2	PS51120
Domain	LY	EGF LRP1B	1.88e-03	15	81	2	SM00135
Domain	LDLR_classB_rpt	EGF LRP1B	1.88e-03	15	81	2	IPR000033
Domain	Znf_FYVE_PHD	ING1 KDM5A ING5 PHF21B	3.83e-03	147	81	4	IPR011011
Domain	zf-RanBP	ZRANB2 NUP153	4.06e-03	22	81	2	PF00641
Domain	ZnF_RBZ	ZRANB2 NUP153	4.43e-03	23	81	2	SM00547
Domain	ZF_RANBP2_2	ZRANB2 NUP153	4.43e-03	23	81	2	PS50199
Domain	ZF_RANBP2_1	ZRANB2 NUP153	4.82e-03	24	81	2	PS01358
Domain	C_TYPE_LECTIN_1	MRC2 CD207 CLEC4G	5.08e-03	80	81	3	PS00615
Domain	Znf_RanBP2	ZRANB2 NUP153	5.22e-03	25	81	2	IPR001876
Domain	cEGF	LTBP1 LRP1B	5.64e-03	26	81	2	IPR026823
Domain	cEGF	LTBP1 LRP1B	5.64e-03	26	81	2	PF12662
Domain	Lectin_C	MRC2 CD207 CLEC4G	5.82e-03	84	81	3	PF00059
Domain	CLECT	MRC2 CD207 CLEC4G	5.82e-03	84	81	3	SM00034
Domain	C_TYPE_LECTIN_2	MRC2 CD207 CLEC4G	6.01e-03	85	81	3	PS50041
Domain	C-type_lectin-like	MRC2 CD207 CLEC4G	6.21e-03	86	81	3	IPR001304
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF7 KLF11 KLF16 KAT2B ZNF219 ING1 KDM5A ING5 WT1 ZNF622 DLL1 ZNF445	4.88e-07	808	83	12	20412781
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KLF11 RBM22 ZNF219 TIMM8B ING1 ZRANB2 NFX1 WT1 BFAR MPND ZNF445	9.98e-07	709	83	11	22988430
Pubmed	Midkine regulates pleiotrophin organ-specific gene expression: evidence for transcriptional regulation and functional redundancy within the pleiotrophin/midkine developmental gene family.	PTN MDK	5.63e-06	2	83	2	15985215
Pubmed	Elevated plasma midkine and pleiotrophin levels in patients with systemic lupus erythematosus.	PTN MDK	5.63e-06	2	83	2	27903979
Pubmed	The heparin binding growth factors midkine and pleiotrophin regulate the antinociceptive effects of morphine through α(2)-adrenergic independent mechanisms.	PTN MDK	5.63e-06	2	83	2	22342918
Pubmed	Co-expression of midkine and pleiotrophin predicts poor survival in human glioma.	PTN MDK	5.63e-06	2	83	2	25001988
Pubmed	Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter.	ZIC1 ZIC2	5.63e-06	2	83	2	11038359
Pubmed	Zic-Proteins Are Repressors of Dopaminergic Forebrain Fate in Mice and C. elegans.	ZIC1 ZIC2	5.63e-06	2	83	2	28972122
Pubmed	Differential phosphoproteome of the striatum from pleiotrophin knockout and midkine knockout mice treated with amphetamine: correlations with amphetamine-induced neurotoxicity.	PTN MDK	5.63e-06	2	83	2	23459167
Pubmed	The role of midkine and pleiotrophin in liver regeneration.	PTN MDK	5.63e-06	2	83	2	15482347
Pubmed	Association of Midkine and Pleiotrophin Gene Polymorphisms With Systemic Lupus Erythematosus Susceptibility in Chinese Han Population.	PTN MDK	5.63e-06	2	83	2	32153561
Pubmed	Genetic inactivation of midkine, not pleiotrophin, facilitates extinction of alcohol-induced conditioned place preference.	PTN MDK	5.63e-06	2	83	2	34358624
Pubmed	Midkine and Pleiotrophin Concentrations in Amniotic Fluid in Healthy and Complicated Pregnancies.	PTN MDK	5.63e-06	2	83	2	27089523
Pubmed	Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs.	PTN MDK	5.63e-06	2	83	2	37850119
Pubmed	Mice doubly deficient in the midkine and pleiotrophin genes exhibit deficits in the expression of beta-tectorin gene and in auditory response.	PTN MDK	5.63e-06	2	83	2	16619002
Pubmed	A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth.	KLF11 KLF14	5.63e-06	2	83	2	21171965
Pubmed	Expression of the heparin-binding growth factors Midkine and pleiotrophin during ocular development.	PTN MDK	5.63e-06	2	83	2	30825522
Pubmed	Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins.	PTN MDK	5.63e-06	2	83	2	1768439
Pubmed	Factor H binds to washed human platelets.	CFH THBS1	5.63e-06	2	83	2	15634279
Pubmed	Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.	PTN MDK	5.63e-06	2	83	2	20308059
Pubmed	Midkine, a newly discovered regulator of the renin-angiotensin pathway in mouse aorta: significance of the pleiotrophin/midkine developmental gene family in angiotensin II signaling.	PTN MDK	5.63e-06	2	83	2	15979460
Pubmed	The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1.	THBS1 MRC2	5.63e-06	2	83	2	35878760
Pubmed	Female infertility in mice deficient in midkine and pleiotrophin, which form a distinct family of growth factors.	PTN MDK	5.63e-06	2	83	2	17121547
Pubmed	Regulation of extinction of cocaine-induced place preference by midkine is related to a differential phosphorylation of peroxiredoxin 6 in dorsal striatum.	PTN MDK	5.63e-06	2	83	2	23891929
Pubmed	HB-GAM/Pleiotrophin and Midkine are differently expressed and distributed during retinoic acid-induced neural differentiation of P19 cells.	PTN MDK	5.63e-06	2	83	2	14708942
Pubmed	Genetic inactivation of pleiotrophin but not midkine potentiates clonidine-induced alpha-2 adrenergic-mediated analgesia.	PTN MDK	5.63e-06	2	83	2	23891830
Pubmed	Behavioral abnormalities of Zic1 and Zic2 mutant mice: implications as models for human neurological disorders.	ZIC1 ZIC2	5.63e-06	2	83	2	11699604
Pubmed	Endogenous pleiotrophin and midkine regulate LPS-induced glial responses.	PTN MDK	5.63e-06	2	83	2	29061398
Pubmed	Distinct expression of midkine and pleiotrophin in the spinal cord and placental tissues during early mouse development.	PTN MDK	5.63e-06	2	83	2	10830434
Pubmed	Epigenetic control of Foxp3 by SMYD3 H3K4 histone methyltransferase controls iTreg development and regulates pathogenic T-cell responses during pulmonary viral infection.	SMYD3 FOXP3	5.63e-06	2	83	2	25669152
Pubmed	Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1).	WT1 MDK	5.63e-06	2	83	2	8950987
Pubmed	Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum.	ZIC1 ZIC2	5.63e-06	2	83	2	25849986
Pubmed	Dependence of cell survival on correlative activities of xanthine oxidase and dihydopyrimidine dehydrogenase in human brain-derived cell culture.	DPYD XDH	5.63e-06	2	83	2	23597150
Pubmed	Recombinant expression and purification of heparin binding proteins: midkine and pleiotrophin from Escherichia coli.	PTN MDK	5.63e-06	2	83	2	22871361
Pubmed	Similarity of the genomic structure between the two members in a new family of heparin-binding factors.	PTN MDK	5.63e-06	2	83	2	1550576
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	RBM22 ING1 KDM5A XRN1 LTBP1	6.89e-06	110	83	5	26841866
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF7 KLF11 KLF16 NFX1 WT1 ZNF267 ZNF622 ZNF396 ZIC1 ZIC2 FOXP3	1.05e-05	908	83	11	19274049
Pubmed	Thrombospondin-1-dependent immune regulation by transforming growth factor-β2-exposed antigen-presenting cells.	THBS1 FOXP3	1.69e-05	3	83	2	26458493
Pubmed	Midkine (MK) expression in extraembryonic tissues, amniotic fluid, and cerebrospinal fluid during mouse embryogenesis.	PTN MDK	1.69e-05	3	83	2	8537330
Pubmed	Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis.	PTN MDK	1.69e-05	3	83	2	7867507
Pubmed	JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis.	DLL1 FOXP3	1.69e-05	3	83	2	17947672
Pubmed	Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.	KLF16 KLF14	1.69e-05	3	83	2	17480121
Pubmed	The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells.	ZIC1 ZIC2	1.69e-05	3	83	2	22024047
Pubmed	Genetic variants in ZIC1, ZIC2, and ZIC3 are not major risk factors for neural tube defects in humans.	ZIC1 ZIC2	1.69e-05	3	83	2	14679585
Pubmed	Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation.	ZIC1 ZIC2	1.69e-05	3	83	2	15261827
Pubmed	The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired.	ZIC1 ZIC2	1.69e-05	3	83	2	8557628
Pubmed	Single-cell RNA-sequencing analysis reveals enhanced non-canonical neurotrophic factor signaling in the subacute phase of traumatic brain injury.	PTN MDK	1.69e-05	3	83	2	37269057
Pubmed	Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets.	ZIC1 ZIC2	1.69e-05	3	83	2	20676059
Pubmed	The large functional spectrum of the heparin-binding cytokines MK and HB-GAM in continuously growing organs: the rodent incisor as a model.	PTN MDK	1.69e-05	3	83	2	18582856
Pubmed	Expression of ZIC family genes in meningiomas and other brain tumors.	ZIC1 ZIC2	1.69e-05	3	83	2	20199689
Pubmed	Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner.	KAT2B FOXP3	1.69e-05	3	83	2	22896699
Pubmed	Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning.	WT1 LAMB1 DLL1	1.95e-05	22	83	3	29449451
Pubmed	Mammalian SP/KLF transcription factors: bring in the family.	KLF11 KLF16 KLF14	2.90e-05	25	83	3	15820306
Pubmed	Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.	PTN VWC2L MDK	3.27e-05	26	83	3	36178190
Pubmed	Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION.	PTN MDK	3.37e-05	4	83	2	27445335
Pubmed	Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease.	PTN MDK	3.37e-05	4	83	2	17368428
Pubmed	Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins.	ZIC1 ZIC2	3.37e-05	4	83	2	11053430
Pubmed	An Evolutionarily Conserved Mesodermal Enhancer in Vertebrate Zic3.	ZIC1 ZIC2	3.37e-05	4	83	2	30297839
Pubmed	Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system.	ZIC1 ZIC2	3.37e-05	4	83	2	15895369
Pubmed	Interactions of LSECtin and DC-SIGN/DC-SIGNR with viral ligands: Differential pH dependence, internalization and virion binding.	CD207 CLEC4G	3.37e-05	4	83	2	18083206
Pubmed	Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.	EED KDM5A	3.37e-05	4	83	2	18483221
Pubmed	A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells.	ZIC1 ZIC2	3.37e-05	4	83	2	7931345
Pubmed	Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.	EIF2AK4 FOXP3	3.37e-05	4	83	2	19366986
Pubmed	Specialized role of migratory dendritic cells in peripheral tolerance induction.	CD207 FOXP3	3.37e-05	4	83	2	23298832
Pubmed	Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene.	KAT2B FOXP3	3.37e-05	4	83	2	24944246
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	NFX1 XRN1 NAP1L4 PEAK1 KCNB2 NUP153	4.10e-05	263	83	6	34702444
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	KAT2B EED ZNF219 GCFC2 ING1 NFX1 WT1 ZNF396 ZIC1 ZIC2	4.56e-05	877	83	10	20211142
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZNF7 CFH RBM22 THBS1 ZNF605 KDM5A LAMB1 C1S MORC3 LRP1B SMYD3 ZNF331	5.29e-05	1285	83	12	35914814
Pubmed	Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.	KAT2B FOXP3	5.60e-05	5	83	2	19996091
Pubmed	Myogenic repressor I-mfa interferes with the function of Zic family proteins.	ZIC1 ZIC2	5.60e-05	5	83	2	15207726
Pubmed	Association study of complement factor H, C2, CFB, and C3 and age-related macular degeneration in a Han Chinese population.	CFH BFAR	5.60e-05	5	83	2	20523265
Pubmed	The functional interactome landscape of the human histone deacetylase family.	RBM22 GCFC2 ING1 GEMIN2 KDM5A NUP153	6.90e-05	289	83	6	23752268
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF7 ZNF587 ZNF267 ZNF417 ZNF445	7.55e-05	181	83	5	37372979
Pubmed	Identification of ALK in Thinness.	PTN MDK	8.39e-05	6	83	2	32442405
Pubmed	Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice.	EIF2AK4 FOXP3	8.39e-05	6	83	2	21145762
Pubmed	Mapping the midkine family of developmentally regulated signaling molecules.	PTN MDK	8.39e-05	6	83	2	8281012
Pubmed	IDO activates regulatory T cells and blocks their conversion into Th17-like T cells.	EIF2AK4 FOXP3	8.39e-05	6	83	2	19635913
Pubmed	Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.	ZIC1 ZIC2	8.39e-05	6	83	2	15465018
Pubmed	Gene expression analysis identifies novel genes participating in early murine liver development and adult liver regeneration.	MDK ZIC1	8.39e-05	6	83	2	16683987
Pubmed	Computer sequence analysis of human highly conserved zinc finger modules.	ZNF7 ZNF587	8.39e-05	6	83	2	10520746
Pubmed	Physical and functional interactions between Zic and Gli proteins.	ZIC1 ZIC2	8.39e-05	6	83	2	11238441
Pubmed	Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells.	EED KDM5A	8.39e-05	6	83	2	20064375
Pubmed	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	KCNH1 EDN1	8.39e-05	6	83	2	23381795
Pubmed	Zic2 patterns binocular vision by specifying the uncrossed retinal projection.	ZIC1 ZIC2	1.17e-04	7	83	2	13678579
Pubmed	Human ING1 proteins differentially regulate histone acetylation.	KAT2B ING1	1.17e-04	7	83	2	12015309
Pubmed	HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors.	MRC2 CD207	1.17e-04	7	83	2	16547227
Pubmed	ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development.	ING5 WT1	1.17e-04	7	83	2	38446206
Pubmed	ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.	ING1 ING5	1.17e-04	7	83	2	16728974
Pubmed	Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression.	THBS1 LTBP1	1.17e-04	7	83	2	19998449
Pubmed	Intronic RNAs mediate EZH2 regulation of epigenetic targets.	EED SMYD3	1.17e-04	7	83	2	22659877
Pubmed	Identification of genes expressed preferentially in the developing peripheral margin of the optic cup.	LTBP1 ZIC1 ZIC2	1.41e-04	42	83	3	19449303
Pubmed	Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome.	EGF MDK EDN1	1.41e-04	42	83	3	29438518
Pubmed	Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis.	KLF11 ZNF283 PEAK1	1.51e-04	43	83	3	11827452
Pubmed	Identification of reference genes suitable for RT-qPCR studies of murine gastrulation and patterning.	ZIC1 ZIC2	1.56e-04	8	83	2	30094508
Pubmed	A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A.	KLF11 KLF16	1.56e-04	8	83	2	11438660
Pubmed	The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation.	ZIC1 ZIC2	1.56e-04	8	83	2	9070329
Pubmed	Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation.	CFH THBS1	1.56e-04	8	83	2	28228282
Pubmed	Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.	NFX1 NUP153	1.56e-04	8	83	2	31375530
Pubmed	Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.	CFH LAMB1	1.56e-04	8	83	2	2993224
Pubmed	WT1-mediated gene regulation in early urogenital ridge development.	WT1 C1S ZIC1	1.73e-04	45	83	3	18391535
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF7 KLF11 KLF16 ZNF219 ZNF605 ZNF337 ZNF587 ZNF283 KLF14 WT1 ZNF267 ZNF396 ZNF417 ZNF829 ZIC1 ZIC2 ZNF331 ZNF445	1.29e-11	718	61	18	28
GeneFamily	PHD finger proteins	ING1 KDM5A NFX1 ING5 PHF21B	1.30e-05	90	61	5	88
GeneFamily	Zinc fingers C2H2-type\|Kruppel like factors	KLF11 KLF16 KLF14	2.88e-05	18	61	3	624
GeneFamily	C-type lectin domain family	MRC2 CD207 CLEC4G	5.33e-04	47	61	3	494
GeneFamily	Low density lipoprotein receptors	LRP12 LRP1B	8.53e-04	13	61	2	634
GeneFamily	WAP four-disulfide core domain containing\|Fibronectin type III domain containing	WFDC11 WFIKKN2	1.65e-03	18	61	2	361
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	ZRANB2 NUP153	2.26e-03	21	61	2	89
GeneFamily	Complement system\|Sushi domain containing	CFH C1S	6.55e-03	36	61	2	492
GeneFamily	Potassium voltage-gated channels	KCNH1 KCNB2	8.04e-03	40	61	2	274
Coexpression	VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN	CFH PTN THBS1 EGF MDK DLL1	4.55e-06	135	83	6	M5825
CoexpressionAtlas	BM Top 100 - ovary	CFH THBS1 WT1 C1S MDK	7.10e-06	70	81	5	BM Top 100 - ovary
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	CFH PTN THBS1 LAMB1 LTBP1	3.49e-05	97	81	5	GSM777043_100
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH PTN MRC2 LAMB1 C1S LTBP1 PEAK1 DLL1	3.93e-09	200	83	8	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFH PTN MRC2 LAMB1 C1S TNFRSF19 LTBP1 MDK	3.93e-09	200	83	8	082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFH PTN MRC2 LAMB1 C1S TNFRSF19 LTBP1 MDK	3.93e-09	200	83	8	731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell	(5)_Fibroblast-B_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFH PTN MRC2 LAMB1 C1S TNFRSF19 LTBP1 MDK	3.93e-09	200	83	8	9bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 WT1 LAMB1 C1S LTBP1 MDK	7.04e-08	191	83	7	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH PTN LAMB1 C1S LTBP1 MDK DLL1	8.69e-08	197	83	7	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	ILEUM-inflamed-(8)_Fibroblast\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CFH PTN MRC2 LAMB1 C1S LTBP1 MDK	9.31e-08	199	83	7	cb3c04b91c8e8080137823b11c76ca0a2adda52d
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ZNF7 CFH MRC2 TMEM266 XDH C1S	6.18e-07	163	83	6	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	CFH C1S LTBP1 KCNB2 POLQ PHF21B	7.12e-07	167	83	6	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH PTN LAMB1 C1S LTBP1 LRP1B	9.67e-07	176	83	6	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH PTN LAMB1 C1S LTBP1 LRP1B	9.67e-07	176	83	6	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS1 MRC2 DNAH17 LAMB1 C1S TNFRSF19	1.00e-06	177	83	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLFN12L GUCY2F MRC2 TNFRSF19 ZIC1 ZIC2	1.03e-06	178	83	6	1802ff1c6cb18ee62cfef7270c0971048fae5315
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast-VLMC_L1-3_CYP1B1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLFN12L GUCY2F MRC2 TNFRSF19 ZIC1 ZIC2	1.03e-06	178	83	6	4368d20130e5a08716564c19470b6014f16902ac
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 LAMB1 TNFRSF19 LTBP1 PEAK1	1.18e-06	182	83	6	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 LAMB1 TNFRSF19 LTBP1 PEAK1	1.18e-06	182	83	6	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF11 KLF16 THBS1 TNFRSF19 DLL1 ADAM8	1.46e-06	189	83	6	1cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell	normal_Lung-Fibroblasts-Undetermined\|normal_Lung / Location, Cell class and cell subclass	CFH MRC2 C1S LTBP1 MDK PHF21B	1.51e-06	190	83	6	30d4658bcc6796f0cdf54cc029f4bb904b13ef66
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH WT1 LAMB1 C1S LTBP1 MDK	1.56e-06	191	83	6	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH WT1 LAMB1 C1S LTBP1 MDK	1.56e-06	191	83	6	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH MRC2 LAMB1 C1S LTBP1 MDK	1.56e-06	191	83	6	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.56e-06	191	83	6	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.56e-06	191	83	6	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH MRC2 LAMB1 C1S TNFRSF19 LTBP1	1.56e-06	191	83	6	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH MRC2 LAMB1 C1S LTBP1 MDK	1.60e-06	192	83	6	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 LAMB1 C1S TNFRSF19 LTBP1	1.60e-06	192	83	6	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH MRC2 LAMB1 C1S PEAK1 MDK	1.60e-06	192	83	6	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 LAMB1 C1S TNFRSF19 LTBP1	1.60e-06	192	83	6	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH MRC2 LAMB1 C1S PEAK1 MDK	1.60e-06	192	83	6	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH PTN THBS1 GEMIN2 C1S ZNF417	1.65e-06	193	83	6	7c0d84b92470bfda2db1e5007feee7c1235a0a78
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.65e-06	193	83	6	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	CFH LAMB1 C1S TNFRSF19 LTBP1 KCNB2	1.65e-06	193	83	6	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.65e-06	193	83	6	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	(1)_Osterolineage_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH PTN MRC2 TNFRSF19 LTBP1 MDK	1.65e-06	193	83	6	035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTN LAMB1 C1S LTBP1 MDK	1.81e-06	196	83	6	2aa1acea3cefb3dbe3afdb04875c96b927e9d860
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTN LAMB1 C1S LTBP1 MDK	1.81e-06	196	83	6	59ca204c96149fdff08bc524cfa832a30e60e8a4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTN LAMB1 C1S LTBP1 MDK	1.81e-06	196	83	6	d06a29775a41223e02728615af519a18f7e82e8b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.81e-06	196	83	6	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.81e-06	196	83	6	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	Mild-CD4+_T_activated\|World / Disease group and Cell class	SLFN12L DHX58 XRN1 ZNF267 MORC3 MDK	1.81e-06	196	83	6	417b4fc2e4388f34c410576131b02936f93e46b6
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.86e-06	197	83	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH PTN LAMB1 C1S MDK DLL1	1.86e-06	197	83	6	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH PTN LAMB1 C1S MDK DLL1	1.86e-06	197	83	6	eb07545bef5ad506fbbe3a1f99131f26c1447a31
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	CFH THBS1 MRC2 LAMB1 C1S LTBP1	1.86e-06	197	83	6	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH LAMB1 TNFRSF19 LTBP1 KCNB2 PHF21B	1.86e-06	197	83	6	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH PTN LAMB1 C1S MDK DLL1	1.92e-06	198	83	6	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CFH MRC2 LAMB1 C1S LTBP1 MDK	1.92e-06	198	83	6	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	Fibroblasts-CD34+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CFH MRC2 LAMB1 C1S LTBP1 MDK	1.97e-06	199	83	6	13ff7409e200a0b46cdb7924d15ef33639693622
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	THBS1 MRC2 LAMB1 C1S LTBP1 PEAK1	1.97e-06	199	83	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFH MRC2 LAMB1 C1S LTBP1 MDK	2.03e-06	200	83	6	e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFH MRC2 LAMB1 C1S LTBP1 MDK	2.03e-06	200	83	6	4dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH PTN MRC2 LAMB1 C1S LTBP1	2.03e-06	200	83	6	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-4\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CFH MRC2 LAMB1 C1S LTBP1 MDK	2.03e-06	200	83	6	bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFH MRC2 LAMB1 C1S LTBP1 MDK	2.03e-06	200	83	6	8256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFH MRC2 LAMB1 C1S LTBP1 MDK	2.03e-06	200	83	6	2cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CFH MRC2 LAMB1 C1S LTBP1 MDK	2.03e-06	200	83	6	8cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH THBS1 MRC2 ZIC1 ZIC2	6.95e-06	142	83	5	f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT2B KCNH1 PHF21B ZNF829 CRB1	7.69e-06	145	83	5	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH THBS1 MRC2 ZIC1 ZIC2	1.20e-05	159	83	5	34c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTN MRC2 C1S LTBP1	1.40e-05	164	83	5	01a7c335897128d3478b8b9b44fb461cab493084
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC2 MDK ZIC1 ZIC2	1.57e-05	168	83	5	9930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC2 MDK ZIC1 ZIC2	1.71e-05	171	83	5	2e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC2 MDK ZIC1 ZIC2	1.71e-05	171	83	5	e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH MRC2 C1S LTBP1 KCNB2	1.76e-05	172	83	5	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC2 MDK ZIC1 ZIC2	1.86e-05	174	83	5	2891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC2 MDK ZIC1 ZIC2	1.86e-05	174	83	5	eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH LAMB1 C1S LTBP1 PEAK1	1.91e-05	175	83	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC2 MDK ZIC1 ZIC2	2.02e-05	177	83	5	599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCell	IIH-matDC\|IIH / Condition, Cell_class and T cell subcluster	PTN GUCY2F C1S LTBP1 ZIC1	2.13e-05	179	83	5	5999c85ce3bab5309ff1ed154be7e32b037750b1
ToppCell	IIH-matDC-\|IIH / Condition, Cell_class and T cell subcluster	PTN GUCY2F C1S LTBP1 ZIC1	2.13e-05	179	83	5	46074b2781ed79e2979428b3ec81504621d3903c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTN MRC2 C1S LTBP1	2.19e-05	180	83	5	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH LAMB1 TNFRSF19 LTBP1 KCNB2	2.19e-05	180	83	5	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPYD ZDHHC23 KCNH1 LAMB1 KCNB2	2.31e-05	182	83	5	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH THBS1 MRC2 LTBP1 PHF21B	2.31e-05	182	83	5	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH MRC2 WT1 C1S LTBP1	2.31e-05	182	83	5	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CFH PTN MRC2 ZIC1 ZIC2	2.43e-05	184	83	5	9f524f0a1e7eb50e3b97a35c0ea7e183a4e99aa8
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CFH PTN MRC2 ZIC1 ZIC2	2.43e-05	184	83	5	779016341dbd6d54b5fdb8711692d31a9b2cec4b
ToppCell	nucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SLFN12L KAT2B NAP1L4 SMAP2 FOXP3	2.49e-05	185	83	5	a86a3a1a187a4d8d7762bc6d3dcb22c982178d22
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH LAMB1 TNFRSF19 LTBP1 MDK	2.56e-05	186	83	5	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH THBS1 MRC2 LAMB1 C1S	2.56e-05	186	83	5	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH LAMB1 TNFRSF19 LTBP1 MDK	2.56e-05	186	83	5	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 WT1 LAMB1 C1S	2.62e-05	187	83	5	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 WT1 LAMB1 C1S	2.62e-05	187	83	5	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 WT1 LAMB1 C1S	2.62e-05	187	83	5	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH PTN GUCY2F KCNH1 DLL1	2.62e-05	187	83	5	39756ab418267151d86f9c2553db859f71900bb1
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH PTN MRC2 LAMB1 LTBP1	2.69e-05	188	83	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 PTN LAMB1 C1S LTBP1	2.76e-05	189	83	5	1db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 PTN LAMB1 C1S LTBP1	2.76e-05	189	83	5	bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ZNF219 MRC2 C1S LTBP1	2.76e-05	189	83	5	dde037322c8caec0c04c5be1c1b59a167824ad9f
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 LAMB1 C1S LTBP1	2.76e-05	189	83	5	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 PTN LAMB1 C1S LTBP1	2.76e-05	189	83	5	14833feea8f80744a06ece73f813eaeff8c4dd61
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH MRC2 LAMB1 C1S TNFRSF19	2.76e-05	189	83	5	e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCell	droplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTN MRC2 C1S LTBP1	2.83e-05	190	83	5	8cb950effc449ae59a915132ecc079be54d1acfe
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 LAMB1 C1S MDK	2.83e-05	190	83	5	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	droplet-Pancreas-Exocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTN MRC2 C1S LTBP1	2.83e-05	190	83	5	5dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCell	droplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTN MRC2 C1S LTBP1	2.83e-05	190	83	5	17a73a658fb30a4322b31e38db7b240023738f29
ToppCell	droplet-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH MRC2 LAMB1 C1S TNFRSF19	2.83e-05	190	83	5	0b7200897b2c389632c9b1ee37e272b811555dbc
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH THBS1 WT1 C1S LTBP1	2.90e-05	191	83	5	f5ce33af56178333730be308253943c54a0724cf
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH MRC2 LAMB1 C1S TNFRSF19	2.90e-05	191	83	5	36467322096bc766cd777dae3bfb4e65511e492c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC2 LAMB1 C1S TNFRSF19	2.90e-05	191	83	5	a261f0738d974784bbdd60f23092bfbcca464459
Drug	LMWH	CFH PTN LRP12 THBS1 EGF LAMB1 C1S HABP2 KCNB2 MDK EDN1 ZIC1	4.93e-06	663	83	12	CID000000772
Drug	Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; PC3; HG-U133A	DPYD THBS1 GCFC2 ZNF337 WT1 BFAR MORC3	7.03e-06	194	83	7	1925_DN
Drug	Reidispongiolide C	EGF GUCY2F WT1 LAMB1 TNFRSF19 EDN1 ZIC1 ZIC2	8.19e-06	279	83	8	CID005289285
Drug	x MK	PTN MDK	1.31e-05	2	83	2	CID000446346
Disease	tumor necrosis factor receptor superfamily member 19 measurement	CFH TNFRSF19	7.44e-06	2	81	2	EFO_0020808
Disease	pleiotrophin measurement	CFH PTN	7.44e-06	2	81	2	EFO_0020651
Disease	interferon gamma receptor 1 measurement	CFH HABP2	7.44e-06	2	81	2	EFO_0020484
Disease	ER membrane protein complex subunit 1 measurement	CFH C1S	4.45e-05	4	81	2	EFO_0801579
Disease	serpin A9 measurement	CFH C1S	4.45e-05	4	81	2	EFO_0802062
Disease	lysophosphatidylcholine acyltransferase 2 measurement	CFH HABP2	7.40e-05	5	81	2	EFO_0801775
Disease	galectin-1 measurement	CFH C1S	7.40e-05	5	81	2	EFO_0020932
Disease	Schwannomatosis, Plexiform	EED WT1	7.40e-05	5	81	2	C0751374
Disease	Reperfusion Injury	THBS1 EGF XDH EDN1	1.08e-04	89	81	4	C0035126
Disease	vasoactive peptide measurement	KCNH1 EDN1	1.11e-04	6	81	2	EFO_0005196
Disease	amyloid beta A4 precursor protein-binding family B member 2 measurement	CFH C1S	1.11e-04	6	81	2	EFO_0801379
Disease	complement C1s subcomponent measurement	CFH C1S	1.11e-04	6	81	2	EFO_0008091
Disease	Neurilemmoma	EED WT1	1.11e-04	6	81	2	C0027809
Disease	clusterin measurement	CFH C1S	1.55e-04	7	81	2	EFO_0007655
Disease	gallbladder cancer (is_marker_for)	DPYD EGF	1.55e-04	7	81	2	DOID:3121 (is_marker_for)
Disease	complement factor H measurement	CFH PTN CRB1	1.97e-04	41	81	3	EFO_0008097
Disease	membranoproliferative glomerulonephritis (implicated_via_orthology)	CFH EDN1	3.30e-04	10	81	2	DOID:2920 (implicated_via_orthology)
Disease	gastrin-releasing peptide measurement	CFH HABP2	4.03e-04	11	81	2	EFO_0022000
Disease	hemopexin measurement	CFH CRB1	4.03e-04	11	81	2	EFO_0008149
Disease	urate measurement, spine bone mineral density	KCNH1 XDH LTBP1	5.51e-04	58	81	3	EFO_0004531, EFO_0007701
Disease	gallbladder cancer (is_implicated_in)	EGF LRP1B	5.69e-04	13	81	2	DOID:3121 (is_implicated_in)
Disease	Mammary Carcinoma, Human	DPYD THBS1 EGF KCNH1 WT1 DLL1 FOXP3	6.06e-04	525	81	7	C4704874
Disease	Mammary Neoplasms, Human	DPYD THBS1 EGF KCNH1 WT1 DLL1 FOXP3	6.06e-04	525	81	7	C1257931
Disease	Mammary Neoplasms	DPYD THBS1 EGF KCNH1 WT1 DLL1 FOXP3	6.20e-04	527	81	7	C1458155
Disease	pancreatic ductal carcinoma (is_marker_for)	THBS1 EGF ADAM8	6.39e-04	61	81	3	DOID:3587 (is_marker_for)
Disease	Breast Carcinoma	DPYD THBS1 EGF KCNH1 WT1 DLL1 FOXP3	7.00e-04	538	81	7	C0678222
Disease	Alobar Holoprosencephaly	DLL1 ZIC2	7.64e-04	15	81	2	C0431363
Disease	Autistic Disorder	DPYD EGF LAMB1 XDH DLL1	7.72e-04	261	81	5	C0004352
Disease	Lobar Holoprosencephaly	DLL1 ZIC2	8.71e-04	16	81	2	C0431362
Disease	Semilobar Holoprosencephaly	DLL1 ZIC2	8.71e-04	16	81	2	C0751617
Disease	heart disease (biomarker_via_orthology)	THBS1 EDN1	9.85e-04	17	81	2	DOID:114 (biomarker_via_orthology)
Disease	myocardial infarction (biomarker_via_orthology)	PTN THBS1 MDK EDN1	1.00e-03	160	81	4	DOID:5844 (biomarker_via_orthology)
Disease	age at menarche	KLF16 DPYD ZRANB2 KLF14 KCNB2 LRP1B ZNF331	1.24e-03	594	81	7	EFO_0004703
Disease	cardiovascular system disease (is_implicated_in)	CFH XDH	1.51e-03	21	81	2	DOID:1287 (is_implicated_in)
Disease	Alveolitis, Fibrosing	EGF LAMB1 EDN1	1.56e-03	83	81	3	C4721507
Disease	nephrosis (biomarker_via_orthology)	CFH EDN1	1.66e-03	22	81	2	DOID:2527 (biomarker_via_orthology)
Disease	Pulmonary Fibrosis	EGF LAMB1 EDN1	1.67e-03	85	81	3	C0034069
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	DPYD KCNB2	1.98e-03	24	81	2	EFO_0003948, EFO_0009923, MONDO_0004247
Disease	endometriosis (is_marker_for)	MDK FOXP3	2.14e-03	25	81	2	DOID:289 (is_marker_for)
Disease	Involutional paraphrenia	XDH EDN1	2.14e-03	25	81	2	C1571983
Disease	Psychosis, Involutional	XDH EDN1	2.14e-03	25	81	2	C1571984
Disease	Involutional Depression	XDH EDN1	2.14e-03	25	81	2	C0011574
Disease	myeloperoxidase measurement	CFH SMG8	2.32e-03	26	81	2	EFO_0005243
Disease	post-traumatic stress disorder	KAT2B KCNB2 PHF21B ZNF331	2.35e-03	202	81	4	EFO_0001358
Disease	Malignant neoplasm of breast	DPYD THBS1 EGF GUCY2F KCNH1 WT1 XDH DLL1 FOXP3	2.71e-03	1074	81	9	C0006142
Disease	pancreatic cancer (is_marker_for)	DPYD THBS1 EGF	2.74e-03	101	81	3	DOID:1793 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCPDEDKKSKAPFWC	ARHGEF10L	766	Q9HCE6
LKKCVCLDDKERWSP	EIF2AK4	516	Q9P2K8
WKRNPDKNCFNCEKL	DPYD	41	Q12882
GFWSKEKPKCVEISC	CFH	196	P08603
CGPEKVCWKGRCQDL	ADAM8	591	P78325
SFWVKGECKRGEECP	RBM22	166	Q9NW64
KIPCNWKKQFGAECK	PTN	86	P21246
DCDGCTIDWKKGKNV	NAP1L4	246	Q99733
LKKLLQRCFEKCPWE	LELP1	36	Q5T871
PFACDWQGCDKKFAR	KLF16	156	Q9BXK1
FRCGNGKCIPEAWKC	LRP12	171	Q9Y561
CKCWPGFQLKDDGKT	LRP1B	2951	Q9NZR2
NGVCKWPGCEKVFEE	FOXP3	196	Q9BZS1
EEGWKKFCLGEKLCA	GEMIN2	141	O14893
KAEESCKCNGWKNPN	KAT2B	101	Q92831
RVPCNWKKEFGADCK	MDK	71	P21741
GTSWGFNKCQKCPKK	LTBP1	586	Q14766
VQCDACLKWRKLPDG	MORC3	411	Q14149
VWKPGECKNCFKPKS	PEAK1	11	Q9H792
CFCGKVKNPEWSRNE	NFX1	421	Q12986
CAKRKSWARFKDACG	KCNH1	831	O95259
KDERWGFCPIKSNDC	MRC2	221	Q9UBG0
WRPAEGRNSNACKKC	LAMB1	321	P07942
SKSCENAIVCWKPGK	EED	321	O75530
CKKLVNPAKKSGCGW	MPND	131	Q8N594
QRPCKDKVDWVQCDG	KDM5A	1616	P29375
CRNPDADEKPWCFIK	HABP2	246	Q14520
EFDNTCCPDKRKKLW	KCNB2	166	Q92953
KKTECPECREKWEGF	BFAR	66	Q9NZS9
KVFHGWLQCDCRPFK	DNAH17	1056	Q9UFH2
VKKCNQVAACLPEKW	GCFC2	696	P16383
WEPEQKLCKLRKGNC	EGF	311	P01133
FCDKPGECKCRVGWQ	DLL1	236	O00548
LLFCPSKKWCEKLAD	POLQ	341	O75417
PRADAKCWFAEGKIC	GUCY2F	446	P51841
CKGAFARELCWPKQG	C20orf85	121	Q9H1P6
KWSNSKLKCQPVDCG	C1S	346	P09871
FKDWKPGGVISCRNC	DHX58	601	Q96C10
TKPKGKWFCPRCVQE	ING5	221	Q8WYH8
EKPFNCSWDGCDKKF	KLF11	421	O14901
GERPFSCDWLDCDKK	KLF14	221	Q8TD94
VKAGCVRKDWCESQP	CRB1	666	P82279
DKKCWNFCQAGKELR	EDN1	116	P05305
CAKCGKKEDIVIPWS	C9orf85	96	Q96MD7
DSCLWKRKRQKCFNP	PHAX	76	Q9H814
KDCPVGKDWKLNCRP	SMG8	246	Q8ND04
KGKWYCPKCRGENEK	ING1	391	Q9UK53
QKKAWPDHKRECKCL	SMYD3	76	Q9H7B4
APCDSEKDGWICEKR	CLEC4G	276	Q6UXB4
WNDAPCDKTFLFICK	CD207	306	Q9UJ71
GPKWKVACNKCNVVA	TOP3B	741	O95985
TKACKKDACPINGGW	THBS1	481	P07996
KPCKCEECGKAFNWS	ZNF826P	146	Q6ZT77
WVCPRCQQKALKKDE	PHF21B	391	Q96EK2
ERFCCAVFAKKPDSW	SLFN12L	326	Q6IEE8
KFCADCQSKGPRWAS	SMAP2	26	Q8WU79
EEKPCKWKECGKVFN	ZNF267	346	Q14586
KWKECGKVFNLNCSL	ZNF267	351	Q14586
CWCGSKDEEAPCKQR	ZNF587	56	Q96SQ5
CWCGSKDEEAPCKQR	ZNF417	56	Q8TAU3
CKECKKAFRWGNQLT	ZNF331	161	Q9NQX6
RKFKEECKSPKAECW	XRN1	1291	Q8IZH2
EKPFSCRWPSCQKKF	WT1	411	P19544
DKFNKENCWKKRGLC	XDH	986	P47989
WCPCSGKKKKDVHAD	SLAMF8	256	Q9P0V8
EKFKKPEGSWDCELC	NUP153	846	P49790
SEEKPWECKICGKTF	ZNF829	151	Q3KNS6
GSPTKAKEDWCAKCQ	ZDHHC23	251	Q8IYP9
FRVSDGDWICPDKKC	ZRANB2	6	O95218
GDWICPDKKCGNVNF	ZRANB2	11	O95218
CWDKCVEKPGNRLDS	TIMM8B	36	Q9Y5J9
CFWEECPREGKPFKA	ZIC1	271	Q15915
STERPFKCQWCGKEF	ZNF445	891	P59923
KEDWGFQKCKPCLDC	TNFRSF19	81	Q9NS68
WKPAQCSKRECQGKQ	VWC2L	206	B2RUY7
VGKICLWCNEKGKSF	ZNF622	301	Q969S3
SWKKQQKCDECGKIF	ZNF396	246	Q96N95
ECSECRKAFAWKPQL	ZNF605	506	Q86T29
ECWGKPNVKECTNKC	WFDC11	41	Q8NEX6
VCGRCFKEPWFLKNH	ZNF219	306	Q9P2Y4
KPCCGKRAAVWQVFL	TMEM266	81	Q2M3C6
KPFKCDECGKAFRWI	ZNF7	411	P17097
VCFWEECPREGKPFK	ZIC2	301	O95409
QPFVCKECGRGFNWK	ZNF337	626	Q9Y3M9
EKPFECKECGKAFSW	ZNF283	456	Q8N7M2
WDGQPVCKCKDRCEK	WFIKKN2	126	Q8TEU8