Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dolichyl-phosphate-mannose-protein mannosyltransferase activity	TMTC3 TMTC2	1.77e-04	8	51	2	GO:0004169
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of sound	SLC12A2 STRC STRCP1	2.58e-05	23	52	3	GO:0050910
GeneOntologyCellularComponent	bBAF complex	SMARCA2 SMARCA4	2.70e-04	10	52	2	GO:0140092
GeneOntologyCellularComponent	npBAF complex	SMARCA2 SMARCA4	5.42e-04	14	52	2	GO:0071564
GeneOntologyCellularComponent	9+2 non-motile cilium	STRC STRCP1	5.42e-04	14	52	2	GO:0097732
GeneOntologyCellularComponent	GBAF complex	SMARCA2 SMARCA4	5.42e-04	14	52	2	GO:0140288
GeneOntologyCellularComponent	kinocilium	STRC STRCP1	5.42e-04	14	52	2	GO:0060091
GeneOntologyCellularComponent	apical part of cell	VANGL2 SLC6A18 SLC12A2 DYNC2LI1 SLC29A2 ABCA7 CRB2	6.24e-04	592	52	7	GO:0045177
GeneOntologyCellularComponent	nBAF complex	SMARCA2 SMARCA4	7.12e-04	16	52	2	GO:0071565
GeneOntologyCellularComponent	apical plasma membrane	VANGL2 SLC6A18 SLC12A2 SLC29A2 ABCA7 CRB2	1.27e-03	487	52	6	GO:0016324
GeneOntologyCellularComponent	stereocilium tip	STRC STRCP1	1.36e-03	22	52	2	GO:0032426
MousePheno	abnormal notochord morphology	VANGL2 INTU DYNC2LI1 CRB2	3.35e-05	63	41	4	MP:0002825
Domain	SnAC	SMARCA2 SMARCA4	6.47e-06	2	48	2	SM01314
Domain	Gln-Leu-Gln_QLQ	SMARCA2 SMARCA4	6.47e-06	2	48	2	IPR014978
Domain	SnAC	SMARCA2 SMARCA4	6.47e-06	2	48	2	IPR029295
Domain	SnAC	SMARCA2 SMARCA4	6.47e-06	2	48	2	PF14619
Domain	QLQ	SMARCA2 SMARCA4	6.47e-06	2	48	2	SM00951
Domain	QLQ	SMARCA2 SMARCA4	6.47e-06	2	48	2	PS51666
Domain	QLQ	SMARCA2 SMARCA4	6.47e-06	2	48	2	PF08880
Domain	HSA	SMARCA2 SMARCA4	3.87e-05	4	48	2	SM00573
Domain	DUF1736	TMTC3 TMTC2	3.87e-05	4	48	2	IPR013618
Domain	HSA	SMARCA2 SMARCA4	3.87e-05	4	48	2	PS51204
Domain	HSA_dom	SMARCA2 SMARCA4	3.87e-05	4	48	2	IPR014012
Domain	DUF1736	TMTC3 TMTC2	3.87e-05	4	48	2	PF08409
Domain	HSA	SMARCA2 SMARCA4	3.87e-05	4	48	2	PF07529
Domain	BRK	SMARCA2 SMARCA4	9.64e-05	6	48	2	SM00592
Domain	BRK_domain	SMARCA2 SMARCA4	9.64e-05	6	48	2	IPR006576
Domain	BRK	SMARCA2 SMARCA4	9.64e-05	6	48	2	PF07533
Domain	MFS_dom	SLC16A13 FLVCR2 SLC29A2 SLC2A3	3.86e-04	134	48	4	IPR020846
Domain	TPR-contain_dom	FANCG TMTC3 PTPN23 TMTC2	5.91e-04	150	48	4	IPR013026
Domain	TPR_REGION	FANCG TMTC3 PTPN23 TMTC2	8.44e-04	165	48	4	PS50293
Domain	TPR	FANCG TMTC3 PTPN23 TMTC2	8.44e-04	165	48	4	PS50005
Domain	Bromodomain_CS	SMARCA2 SMARCA4	2.02e-03	26	48	2	IPR018359
Domain	MFS	SLC16A13 FLVCR2 SLC2A3	2.69e-03	108	48	3	PS50850
Domain	-	DNHD1 DYNC2LI1 SMARCA2 SMARCA4 CMPK2 ABCA7 ATL1	2.79e-03	746	48	7	3.40.50.300
Domain	SNF2_N	SMARCA2 SMARCA4	3.05e-03	32	48	2	IPR000330
Domain	SNF2_N	SMARCA2 SMARCA4	3.05e-03	32	48	2	PF00176
Domain	BROMODOMAIN_1	SMARCA2 SMARCA4	4.07e-03	37	48	2	PS00633
Domain	Bromodomain	SMARCA2 SMARCA4	4.29e-03	38	48	2	PF00439
Domain	TPR	FANCG TMTC3 TMTC2	4.44e-03	129	48	3	SM00028
Domain	TPR_repeat	FANCG TMTC3 TMTC2	4.83e-03	133	48	3	IPR019734
Domain	BROMODOMAIN_2	SMARCA2 SMARCA4	4.98e-03	41	48	2	PS50014
Domain	BROMO	SMARCA2 SMARCA4	5.22e-03	42	48	2	SM00297
Domain	Bromodomain	SMARCA2 SMARCA4	5.22e-03	42	48	2	IPR001487
Domain	-	SMARCA2 SMARCA4	5.22e-03	42	48	2	1.20.920.10
Domain	P-loop_NTPase	DNHD1 DYNC2LI1 SMARCA2 SMARCA4 CMPK2 ABCA7 ATL1	5.63e-03	848	48	7	IPR027417
Domain	ER_TARGET	FKBP9 CERCAM	6.49e-03	47	48	2	PS00014
Domain	TPR_8	TMTC3 TMTC2	8.20e-03	53	48	2	PF13181
Pubmed	Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.	SMARCA2 SMARCA4	2.19e-06	2	52	2	18508913
Pubmed	The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.	SMARCA2 SMARCA4	2.19e-06	2	52	2	8670841
Pubmed	Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.	SMARCA2 SMARCA4	2.19e-06	2	52	2	11719516
Pubmed	Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.	SMARCA2 SMARCA4	2.19e-06	2	52	2	23163725
Pubmed	The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.	SMARCA2 SMARCA4	2.19e-06	2	52	2	25808524
Pubmed	Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.	SMARCA2 SMARCA4	2.19e-06	2	52	2	19144648
Pubmed	Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.	SMARCA2 SMARCA4	2.19e-06	2	52	2	23076393
Pubmed	DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.	SMARCA2 SMARCA4	2.19e-06	2	52	2	28706277
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	2.19e-06	2	52	2	34910522
Pubmed	Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.	SMARCA2 SMARCA4	2.19e-06	2	52	2	9603422
Pubmed	The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.	SMARCA2 SMARCA4	2.19e-06	2	52	2	15576411
Pubmed	[Expression of BRG1 and BRM proteins in prostatic cancer].	SMARCA2 SMARCA4	2.19e-06	2	52	2	21092585
Pubmed	High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.	SMARCA2 SMARCA4	2.19e-06	2	52	2	29391527
Pubmed	SWI/SNF gene variants and glioma risk and outcome.	SMARCA2 SMARCA4	2.19e-06	2	52	2	23276717
Pubmed	Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.	SMARCA2 SMARCA4	2.19e-06	2	52	2	27097303
Pubmed	Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.	SMARCA2 SMARCA4	2.19e-06	2	52	2	15240517
Pubmed	Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.	SMARCA2 SMARCA4	2.19e-06	2	52	2	26564006
Pubmed	Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.	SMARCA2 SMARCA4	2.19e-06	2	52	2	37634210
Pubmed	SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.	SMARCA2 SMARCA4	2.19e-06	2	52	2	26551623
Pubmed	SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.	SMARCA2 SMARCA4	2.19e-06	2	52	2	33027072
Pubmed	SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.	SMARCA2 SMARCA4	2.19e-06	2	52	2	28038711
Pubmed	A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.	SMARCA2 SMARCA4	2.19e-06	2	52	2	23872584
Pubmed	SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.	SMARCA2 SMARCA4	2.19e-06	2	52	2	19458193
Pubmed	Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.	SMARCA2 SMARCA4	2.19e-06	2	52	2	23963727
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	2.19e-06	2	52	2	11687802
Pubmed	SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.	SMARCA2 SMARCA4	2.19e-06	2	52	2	12493776
Pubmed	Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.	SMARCA2 SMARCA4	2.19e-06	2	52	2	31375262
Pubmed	Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.	SMARCA2 SMARCA4	2.19e-06	2	52	2	23088494
Pubmed	Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.	SMARCA2 SMARCA4	2.19e-06	2	52	2	17075831
Pubmed	Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.	SMARCA2 SMARCA4	2.19e-06	2	52	2	8208605
Pubmed	The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.	SMARCA2 SMARCA4	2.19e-06	2	52	2	34289068
Pubmed	SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.	SMARCA2 SMARCA4	2.19e-06	2	52	2	34518526
Pubmed	SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.	SMARCA2 SMARCA4	2.19e-06	2	52	2	20333683
Pubmed	SMARCA family of genes.	SMARCA2 SMARCA4	2.19e-06	2	52	2	32312722
Pubmed	SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.	SMARCA2 SMARCA4	2.19e-06	2	52	2	34812766
Pubmed	Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.	SMARCA2 SMARCA4	2.19e-06	2	52	2	26356327
Pubmed	Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.	SMARCA2 SMARCA4	2.19e-06	2	52	2	32855269
Pubmed	Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.	SMARCA2 SMARCA4	2.19e-06	2	52	2	30478150
Pubmed	Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.	SMARCA2 SMARCA4	2.19e-06	2	52	2	12566296
Pubmed	A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.	SMARCA2 SMARCA4	2.19e-06	2	52	2	11163203
Pubmed	Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.	SMARCA2 SMARCA4	2.19e-06	2	52	2	12620226
Pubmed	SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.	SMARCA2 SMARCA4	2.19e-06	2	52	2	31406271
Pubmed	BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.	SMARCA2 SMARCA4	2.19e-06	2	52	2	27039070
Pubmed	Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.	SMARCA2 SMARCA4	2.19e-06	2	52	2	29848589
Pubmed	Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.	SMARCA2 SMARCA4	2.19e-06	2	52	2	29273066
Pubmed	Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.	SMARCA2 SMARCA4	2.19e-06	2	52	2	22721696
Pubmed	Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.	WASHC4 NBEAL1 SMARCA2 RANBP6 VPS13B	3.85e-06	157	52	5	12466305
Pubmed	Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models.	SMARCA2 SMARCA4	6.57e-06	3	52	2	28292935
Pubmed	The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes.	SMARCA2 SMARCA4	6.57e-06	3	52	2	17938176
Pubmed	Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.	SMARCA2 SMARCA4	6.57e-06	3	52	2	36464671
Pubmed	Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart.	SMARCA2 SMARCA4	6.57e-06	3	52	2	22740088
Pubmed	BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2.	SMARCA2 SMARCA4	6.57e-06	3	52	2	15034933
Pubmed	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1.	SMARCA2 SMARCA4	6.57e-06	3	52	2	30287812
Pubmed	TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival.	SMARCA2 SMARCA4	6.57e-06	3	52	2	15075294
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	6.57e-06	3	52	2	30801007
Pubmed	A putative nuclear receptor coactivator (TMF/ARA160) associates with hbrm/hSNF2 alpha and BRG-1/hSNF2 beta and localizes in the Golgi apparatus.	SMARCA2 SMARCA4	6.57e-06	3	52	2	12044884
Pubmed	SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development.	SMARCA2 SMARCA4	6.57e-06	3	52	2	21518954
Pubmed	Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma.	SMARCA2 SMARCA4	6.57e-06	3	52	2	19784067
Pubmed	FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.	FRMD8 FRMD8P1	6.57e-06	3	52	2	37527040
Pubmed	Characterization of mammary tumors from Brg1 heterozygous mice.	SMARCA2 SMARCA4	6.57e-06	3	52	2	17637742
Pubmed	The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.	FRMD8 FRMD8P1	6.57e-06	3	52	2	36720499
Pubmed	BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.	SMARCA2 SMARCA4	6.57e-06	3	52	2	20571081
Pubmed	Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers.	SMARCA2 SMARCA4	6.57e-06	3	52	2	14603256
Pubmed	SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility†.	SMARCA2 SMARCA4	6.57e-06	3	52	2	36440965
Pubmed	Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2.	SMARCA2 SMARCA4	6.57e-06	3	52	2	9099865
Pubmed	BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes.	SMARCA2 SMARCA4	1.31e-05	4	52	2	23897427
Pubmed	Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins.	TMTC3 TMTC2	1.31e-05	4	52	2	28973932
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	1.31e-05	4	52	2	18849963
Pubmed	Dual role of NRSF/REST in activation and repression of the glucocorticoid response.	SMARCA2 SMARCA4	1.31e-05	4	52	2	17984088
Pubmed	Neuregulin-1 modulates the differentiation of neural stem cells in vitro through an interaction with the Swi/Snf complex.	SMARCA2 SMARCA4	1.31e-05	4	52	2	19781646
Pubmed	Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.	SMARCA2 SMARCA4	1.31e-05	4	52	2	31906887
Pubmed	Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding sites.	TMTC3 TMTC2	1.31e-05	4	52	2	33436046
Pubmed	Brahma safeguards canalization of cardiac mesoderm differentiation.	SMARCA2 SMARCA4	1.31e-05	4	52	2	35082446
Pubmed	Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.	SMARCA2 SMARCA4	1.31e-05	4	52	2	19805516
Pubmed	SWI/SNF chromatin-remodeling enzymes Brahma-related gene 1 (BRG1) and Brahma (BRM) are dispensable in multiple models of postnatal angiogenesis but are required for vascular integrity in infant mice.	SMARCA2 SMARCA4	1.31e-05	4	52	2	25904594
Pubmed	BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility.	SMARCA2 SMARCA4	1.31e-05	4	52	2	28232072
Pubmed	The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes.	SMARCA2 SMARCA4	1.31e-05	4	52	2	33481850
Pubmed	Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.	SMARCA2 SMARCA4	1.31e-05	4	52	2	9744861
Pubmed	BRM (SNF2alpha) expression is concomitant to the onset of vasculogenesis in early mouse postimplantation development.	SMARCA2 SMARCA4	1.31e-05	4	52	2	11231080
Pubmed	Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.	SMARCA2 SMARCA4	1.31e-05	4	52	2	24421395
Pubmed	Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.	SMARCA2 SMARCA4	1.31e-05	4	52	2	16452305
Pubmed	BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists.	SMARCA2 SMARCA4	1.31e-05	4	52	2	15141164
Pubmed	Control of B cell development by the histone H2A deubiquitinase MYSM1.	SMARCA2 SMARCA4	1.31e-05	4	52	2	22169041
Pubmed	alphaII-Spectrin interacts with five groups of functionally important proteins in the nucleus.	FANCG SMARCA2 SMARCA4	1.83e-05	34	52	3	16889989
Pubmed	Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cells.	SMARCA2 SMARCA4	2.19e-05	5	52	2	25801033
Pubmed	FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.	FRMD8 FRMD8P1	2.19e-05	5	52	2	29897336
Pubmed	iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.	FRMD8 FRMD8P1	2.19e-05	5	52	2	29897333
Pubmed	Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression.	SMARCA2 SMARCA4	2.19e-05	5	52	2	20011120
Pubmed	Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.	SMARCA2 SMARCA4	2.19e-05	5	52	2	18487222
Pubmed	Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).	SMARCA2 SMARCA4	2.19e-05	5	52	2	9843504
Pubmed	The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression.	SMARCA2 SMARCA4	2.19e-05	5	52	2	19342595
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	2.19e-05	5	52	2	24920589
Pubmed	Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.	SMARCA2 SMARCA4	2.19e-05	5	52	2	12200431
Pubmed	Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth.	SMARCA2 SMARCA4	2.19e-05	5	52	2	12065415
Pubmed	The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.	SMARCA2 SMARCA4	3.28e-05	6	52	2	16230384
Pubmed	Numerous BAF complex genes are mutated in Coffin-Siris syndrome.	SMARCA2 SMARCA4	3.28e-05	6	52	2	25081545
Pubmed	A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.	SMARCA2 SMARCA4	3.28e-05	6	52	2	10619021
Pubmed	Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.	SMARCA2 SMARCA4	3.28e-05	6	52	2	16940996
Pubmed	Activation of ATP-binding cassette transporter A1 transcription by chromatin remodeling complex.	SMARCA2 SMARCA4	3.28e-05	6	52	2	15774904
Pubmed	Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.	FRMD8 FRMD8P1	3.28e-05	6	52	2	29776906
Cytoband	11q13	FRMD8 SLC29A2 RASGRP2	3.34e-04	118	52	3	11q13
Cytoband	15q15.3	STRC STRCP1	3.71e-04	25	52	2	15q15.3
GeneFamily	Solute carriers	SLC6A18 SLC16A13 SLC12A2 FLVCR2 SLC29A2 SLC2A3	9.94e-05	395	35	6	752
Drug	Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A	PIK3CD PCSK7 ABCA7 VPS13B SLC2A3 RASGRP2	4.24e-06	195	50	6	2317_UP
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	2.70e-06	2	49	2	DOID:0110471 (implicated_via_orthology)
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	SMARCA2 SMARCA4	2.69e-05	5	49	2	C3281201
Disease	asphyxiating thoracic dystrophy (is_implicated_in)	INTU DYNC2LI1	5.64e-05	7	49	2	DOID:0050592 (is_implicated_in)
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA2 SMARCA4	9.65e-05	9	49	2	DOID:0050340 (implicated_via_orthology)
Disease	Coffin-Siris syndrome	SMARCA2 SMARCA4	2.08e-04	13	49	2	C0265338
Disease	cholelithiasis	UGT1A3 FGFR4 VPS13B	4.28e-04	88	49	3	EFO_0004799
Disease	lifestyle measurement, alcohol consumption measurement	INTU RANBP6 BACE2	9.32e-04	115	49	3	EFO_0007878, EFO_0010724
Disease	cancer (implicated_via_orthology)	PIK3CD SMARCA2 SMARCA4 RANBP6	1.02e-03	268	49	4	DOID:162 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FLLLPPLLWREELEP	VANGL2	126	Q9ULK5
QVPLPWLATGLLLLL	UGT1A3	6	P35503
PLLAQWLLRAAPELA	BACE2	11	Q9Y5Z0
LAGLVSLDLPLDPLW	FGFR4	446	P22455
EALIWLDPLPLEENR	DNHD1	3561	Q96M86
PHWPKELLQLLLELL	DNHD1	4161	Q96M86
QPVQLLVELLWPLFL	ABCA7	21	Q8IZY2
PLLLLIQWLPELQSH	NBEAL1	446	Q6ZS30
DDPLSLLDPLWTLNK	PTPN23	1621	Q9H3S7
LDWSQDLLPLSLIPV	PAN2	386	Q504Q3
LVALQLALPDWLDPA	RASGRP2	311	Q7LDG7
PQALASVLLLLLWAP	CRB2	11	Q5IJ48
ALWLVSPLLEVQLKP	FRMD8	76	Q9BZ67
ALWLVSPLLEVQLKP	FRMD8P1	76	Q9BZ68
LVLVLDLSKPNDLWP	DYNC2LI1	111	Q8TCX1
LDAPLGLPTCLWLEL	PCSK7	11	Q16549
LPGLLHLEIDNWPLL	LINGO3	221	P0C6S8
LPALCEPGDLLELLW	LRATD1	116	Q96KN4
WDLLALPPQDIILAS	METTL23	86	Q86XA0
DLLLLLKTWSPPAEE	FANCG	176	O15287
LLDNLPGVRWLTLPL	INTU	466	Q9ULD6
PPLLLLLLWVTGQAA	FKBP9	11	O95302
QWPEDLLKPDLILLL	CMPK2	361	Q5EBM0
NLKILIPWLLSPESL	ATL1	296	Q8WXF7
LLLLPVCAWGLLPQL	CACNA2D4	1121	Q7Z3S7
QAWPNFLPLVVLVLL	IGFLR1	156	Q9H665
PLLLPVAWLLEKFGL	FLVCR2	136	Q9UPI3
PALWRLPEELLLLIC	FBXW4	26	P57775
EELWPLLLGFTILPA	SLC2A3	181	P11169
PAQLLGLLLLWLPDT	IGKV1-27	6	A0A075B6S5
LSILWIDPDDFPLLV	CASQ2	301	O14958
AAPLLQLLLLLGPWL	CERCAM	6	Q5T4B2
WLLGPEVDILPFLLL	HGH1	236	Q9BTY7
LEELLDVLQSLPPAW	STK11IP	901	Q8N1F8
FLWPDEDSRLLPLLV	SLC29A2	351	Q14542
NKLPELWALLNFLLP	SMARCA2	886	P51531
NKLPELWALLNFLLP	SMARCA4	916	P51532
LPWFEQLLPLIVNLI	RANBP6	866	O60518
LLWAVLPLLPHLPLE	STRC	866	Q7RTU9
LLPVLWVPVAALAQL	SLC6A18	576	Q96N87
GLVLAPELLLDPWQV	RHBDD3	36	Q9Y3P4
PLLWAVLLLPAVALV	ZP1	601	P60852
LQDLDWDPLPAAFLL	SLC16A13	241	Q7RTY0
LPTKNLWLLLCPDTL	TMTC2	276	Q8N394
WLEALSKDLPPILLV	SLC12A2	1186	P55011
DLEIALLLPLPWALQ	MT-ND3	66	P03897
WPELPVLSALELLDF	PIK3CD	571	O00329
DRLPALAWLLLQDLP	PRRT4	426	C9JH25
LAWLLLQDLPLPCLA	PRRT4	431	C9JH25
LLIELLPWALLINES	VPS13B	2981	Q7Z7G8
VWDFNLDPIALKLLP	WASHC4	56	Q2M389
LLWAVLPLLPHLPLE	STRCP1	866	A6NGW2
WPDCLLPLLPLKLLQ	STRCP1	1131	A6NGW2
LLPVNAWLLLNPSEL	TMTC3	286	Q6ZXV5
PVWILDNILDQLIFP	TFIP11	516	Q9UBB9
LGAEEPLPARIWLQL	N4BP1	41	O75113