Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme binding	MARCHF6 SIAH1 SIAH2 ARIH1	6.10e-05	36	119	4	GO:0031624
GeneOntologyMolecularFunction	ATP-dependent activity	MYH2 ERCC6 MYO1E DYNC2H1 HSPH1 RNF213 DHX57 ABCB4 MMAA MDN1 MYO1F ABCC12 DNAH6	7.64e-05	614	119	13	GO:0140657
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme binding	MARCHF6 SIAH1 SIAH2 ARIH1	1.13e-04	42	119	4	GO:0044390
GeneOntologyMolecularFunction	cytoskeletal protein binding	MYH2 ANK1 MYO1E SYNE1 SPTA1 HSPH1 CEP290 NEB RMDN2 BICD1 MYL9 SYNE2 MYO1F SSH2 ALDOB MYL12B NOS2	2.77e-04	1099	119	17	GO:0008092
GeneOntologyMolecularFunction	ATP hydrolysis activity	ERCC6 MYO1E DYNC2H1 RNF213 DHX57 ABCB4 MMAA MDN1 ABCC12 DNAH6	3.11e-04	441	119	10	GO:0016887
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	3.48e-04	5	119	2	GO:0140444
GeneOntologyMolecularFunction	pyrophosphatase activity	GTPBP4 ERCC6 MYO1E CILP DYNC2H1 RNF213 DHX57 ABCB4 MMAA MDN1 RAB2B ABCC12 DNAH6 RAB5B	4.74e-04	839	119	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	GTPBP4 ERCC6 MYO1E CILP DYNC2H1 RNF213 DHX57 ABCB4 MMAA MDN1 RAB2B ABCC12 DNAH6 RAB5B	4.79e-04	840	119	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GTPBP4 ERCC6 MYO1E CILP DYNC2H1 RNF213 DHX57 ABCB4 MMAA MDN1 RAB2B ABCC12 DNAH6 RAB5B	4.79e-04	840	119	14	GO:0016818
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH2 MYO1E DYNC2H1 MYO1F DNAH6	7.07e-04	118	119	5	GO:0003774
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	GTPBP4 ERCC6 MYO1E DYNC2H1 RNF213 DHX57 ABCB4 MMAA MDN1 RAB2B ABCC12 DNAH6 RAB5B	7.25e-04	775	119	13	GO:0017111
GeneOntologyMolecularFunction	dynein intermediate chain binding	DYNC2H1 BICD1 DNAH6	1.38e-03	37	119	3	GO:0045505
GeneOntologyMolecularFunction	microfilament motor activity	MYH2 MYO1E MYO1F	1.50e-03	38	119	3	GO:0000146
GeneOntologyCellularComponent	cell cortex	MYH2 ANK1 MYO1E SPTA1 NEDD9 MYL9 GYS2 MYO1F NR3C2 MYL12B NOS2	8.33e-06	371	118	11	GO:0005938
GeneOntologyCellularComponent	cortical cytoskeleton	MYH2 ANK1 MYO1E SPTA1 GYS2 MYO1F NOS2	8.64e-06	129	118	7	GO:0030863
GeneOntologyCellularComponent	myosin complex	MYH2 MYO1E MYL9 MYO1F MYL12B	2.07e-05	59	118	5	GO:0016459
GeneOntologyCellularComponent	sarcomere	MYH2 ANK1 SYNE1 NEB MYL9 SYNE2 PYGM MYL12B	8.58e-05	249	118	8	GO:0030017
GeneOntologyCellularComponent	myofibril	MYH2 ANK1 SYNE1 NEB MYL9 SYNE2 PYGM MYL12B	1.62e-04	273	118	8	GO:0030016
GeneOntologyCellularComponent	cortical actin cytoskeleton	MYH2 MYO1E SPTA1 GYS2 MYO1F	1.84e-04	93	118	5	GO:0030864
GeneOntologyCellularComponent	Z disc	ANK1 NEB MYL9 SYNE2 PYGM MYL12B	2.18e-04	151	118	6	GO:0030018
GeneOntologyCellularComponent	contractile muscle fiber	MYH2 ANK1 SYNE1 NEB MYL9 SYNE2 PYGM MYL12B	2.44e-04	290	118	8	GO:0043292
GeneOntologyCellularComponent	I band	ANK1 NEB MYL9 SYNE2 PYGM MYL12B	3.63e-04	166	118	6	GO:0031674
GeneOntologyCellularComponent	myosin II complex	MYH2 MYL9 MYL12B	5.18e-04	28	118	3	GO:0016460
GeneOntologyCellularComponent	centriolar satellite	CEP290 TTC8 TACC3 ALDOB PCNT	8.01e-04	128	118	5	GO:0034451
GeneOntologyCellularComponent	supramolecular fiber	MYH2 ANK1 DYNC2H1 SYNE1 HSPH1 NEB RMDN2 SPECC1 BICD1 MYL9 SYNE2 MYO1F PYGM MYL12B DNAH6 PCNT	9.66e-04	1179	118	16	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	MYH2 ANK1 DYNC2H1 SYNE1 HSPH1 NEB RMDN2 SPECC1 BICD1 MYL9 SYNE2 MYO1F PYGM MYL12B DNAH6 PCNT	1.04e-03	1187	118	16	GO:0099081
GeneOntologyCellularComponent	intercellular canaliculus	DPP4 ABCB4	1.11e-03	9	118	2	GO:0046581
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	ANK1 SPTA1	1.11e-03	9	118	2	GO:0014731
GeneOntologyCellularComponent	sarcoplasmic reticulum	ANK1 THBS4 SYNE2 PYGM	1.56e-03	88	118	4	GO:0016529
GeneOntologyCellularComponent	actin cytoskeleton	MYH2 MYO1E SPTA1 NEB ADAM8 SPECC1 MYL9 GYS2 MYO1F MYL12B	1.59e-03	576	118	10	GO:0015629
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	1.68e-03	11	118	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	1.68e-03	11	118	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	1.68e-03	11	118	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	1.68e-03	11	118	2	GO:0106094
GeneOntologyCellularComponent	microtubule organizing center	CEP290 CCDC141 SPECC1 BICD1 IVL NEDD9 TTC8 KIAA1217 CEP152 CEP126 TACC3 ALDOB PCNT	2.06e-03	919	118	13	GO:0005815
GeneOntologyCellularComponent	cuticular plate	MYO1E SPTA1	2.37e-03	13	118	2	GO:0032437
GeneOntologyCellularComponent	focal adhesion	DPP4 ITGA11 ABCB4 NEDD9 JAK1 SYNE2 TSPAN4 SSH2	3.11e-03	431	118	8	GO:0005925
GeneOntologyCellularComponent	muscle myosin complex	MYH2 MYL9	3.60e-03	16	118	2	GO:0005859
GeneOntologyCellularComponent	cell-substrate junction	DPP4 ITGA11 ABCB4 NEDD9 JAK1 SYNE2 TSPAN4 SSH2	3.67e-03	443	118	8	GO:0030055
MousePheno	decreased cellular hemoglobin content	ANK1 SPTA1 JAK1	3.87e-05	10	98	3	MP:0008956
MousePheno	gallstones	ANK1 SPTA1 ABCB4	3.87e-05	10	98	3	MP:0002830
MousePheno	abnormal cellular hemoglobin content	ANK1 SPTA1 JAK1	7.02e-05	12	98	3	MP:0008954
MousePheno	abnormal kidney cortex morphology	ANK1 MYO1E GNE SPTA1 CEP290 JAK1 GUSB PDS5A NR3C2 PCNT	8.97e-05	324	98	10	MP:0000521
Domain	P-loop_NTPase	GTPBP4 MYH2 NWD1 ERCC6 MYO1E DYNC2H1 RNF213 DHX57 ABCB4 MMAA MDN1 LRRIQ1 MYO1F RAB2B ABCC12 DNAH6 RAB5B NLRP8	5.39e-06	848	117	18	IPR027417
Domain	Spectrin	SYNE1 SPTA1 CCDC141 SYNE2	1.18e-05	23	117	4	PF00435
Domain	-	GTPBP4 NWD1 ERCC6 MYO1E DYNC2H1 RNF213 DHX57 ABCB4 MMAA MDN1 MYO1F RAB2B ABCC12 DNAH6 RAB5B NLRP8	1.67e-05	746	117	16	3.40.50.300
Domain	Spectrin_repeat	SYNE1 SPTA1 CCDC141 SYNE2	3.08e-05	29	117	4	IPR002017
Domain	AAA	DYNC2H1 RNF213 ABCB4 MMAA MDN1 ABCC12 DNAH6	3.42e-05	144	117	7	SM00382
Domain	AAA+_ATPase	DYNC2H1 RNF213 ABCB4 MMAA MDN1 ABCC12 DNAH6	3.42e-05	144	117	7	IPR003593
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 MDN1 DNAH6	8.29e-05	14	117	3	IPR011704
Domain	AAA_5	DYNC2H1 MDN1 DNAH6	8.29e-05	14	117	3	PF07728
Domain	7-in-absentia-prot_TRAF-dom	SIAH1 SIAH2	1.16e-04	3	117	2	IPR018121
Domain	Sina	SIAH1 SIAH2	1.16e-04	3	117	2	PF03145
Domain	KASH	SYNE1 SYNE2	2.32e-04	4	117	2	IPR012315
Domain	KASH	SYNE1 SYNE2	2.32e-04	4	117	2	PS51049
Domain	SINA-like	SIAH1 SIAH2	2.32e-04	4	117	2	IPR004162
Domain	Znf_SIAH	SIAH1 SIAH2	2.32e-04	4	117	2	IPR013010
Domain	KASH	SYNE1 SYNE2	2.32e-04	4	117	2	SM01249
Domain	KASH	SYNE1 SYNE2	2.32e-04	4	117	2	PF10541
Domain	ZF_SIAH	SIAH1 SIAH2	3.84e-04	5	117	2	PS51081
Domain	SH3_domain	DOCK4 MYO1E SPTA1 NEB NEDD9 MYO1F ZNF582	4.74e-04	220	117	7	IPR001452
Domain	FAT	ATR TMTC1	5.74e-04	6	117	2	PF02259
Domain	PIK-rel_kinase_FAT	ATR TMTC1	5.74e-04	6	117	2	IPR003151
Domain	Myosin_TH1	MYO1E MYO1F	8.00e-04	7	117	2	PF06017
Domain	Myosin_TH1	MYO1E MYO1F	8.00e-04	7	117	2	IPR010926
Domain	TH1	MYO1E MYO1F	8.00e-04	7	117	2	PS51757
Domain	HEAT_REPEAT	IPO5 PDS5B ATR PDS5A	9.75e-04	70	117	4	PS50077
Domain	IQ	MYH2 MYO1E LRRIQ1 MYO1F	1.03e-03	71	117	4	PF00612
Domain	SPEC	SYNE1 SPTA1 SYNE2	1.04e-03	32	117	3	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTA1 SYNE2	1.04e-03	32	117	3	IPR018159
Domain	Myosin_head_motor_dom	MYH2 MYO1E MYO1F	1.72e-03	38	117	3	IPR001609
Domain	MYOSIN_MOTOR	MYH2 MYO1E MYO1F	1.72e-03	38	117	3	PS51456
Domain	Myosin_head	MYH2 MYO1E MYO1F	1.72e-03	38	117	3	PF00063
Domain	MYSc	MYH2 MYO1E MYO1F	1.72e-03	38	117	3	SM00242
Domain	-	ATR RMDN2 TTK TTC8 TMTC1 RGPD3	1.94e-03	207	117	6	1.25.40.10
Domain	DHR-1_domain	DOCK4 DOCK11	2.06e-03	11	117	2	IPR027007
Domain	DHR_2	DOCK4 DOCK11	2.06e-03	11	117	2	PS51651
Domain	DHR_1	DOCK4 DOCK11	2.06e-03	11	117	2	PS51650
Domain	DHR-2	DOCK4 DOCK11	2.06e-03	11	117	2	PF06920
Domain	DOCK	DOCK4 DOCK11	2.06e-03	11	117	2	IPR026791
Domain	DOCK_C	DOCK4 DOCK11	2.06e-03	11	117	2	IPR010703
Domain	DOCK-C2	DOCK4 DOCK11	2.06e-03	11	117	2	PF14429
Domain	DHR-2	DOCK4 DOCK11	2.06e-03	11	117	2	IPR027357
Domain	SH3	DOCK4 MYO1E SPTA1 NEB NEDD9 MYO1F	2.41e-03	216	117	6	SM00326
Domain	SH3	DOCK4 MYO1E SPTA1 NEB NEDD9 MYO1F	2.41e-03	216	117	6	PS50002
Domain	IQ_motif_EF-hand-BS	MYH2 MYO1E LRRIQ1 MYO1F	2.47e-03	90	117	4	IPR000048
Domain	IQ	MYH2 MYO1E LRRIQ1 MYO1F	2.78e-03	93	117	4	PS50096
Domain	EF-hand_6	MYL9 MYL12B	2.90e-03	13	117	2	PF13405
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH6	3.37e-03	14	117	2	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH6	3.37e-03	14	117	2	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH6	3.37e-03	14	117	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH6	3.37e-03	14	117	2	PF08393
Domain	-	SIAH1 SIAH2	3.37e-03	14	117	2	3.90.890.10
Domain	-	SIAH1 SIAH2	3.37e-03	14	117	2	2.60.210.10
Domain	MT	DYNC2H1 DNAH6	3.37e-03	14	117	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH6	3.37e-03	14	117	2	PF12780
Domain	TPR-like_helical_dom	ATR RMDN2 TTK TTC8 TMTC1 RGPD3	3.50e-03	233	117	6	IPR011990
Domain	SH3_1	MYO1E SPTA1 NEB NEDD9 MYO1F	3.73e-03	164	117	5	PF00018
Domain	DHC_fam	DYNC2H1 DNAH6	3.87e-03	15	117	2	IPR026983
Domain	Dynein_heavy	DYNC2H1 DNAH6	3.87e-03	15	117	2	PF03028
Domain	Dynein_heavy_dom	DYNC2H1 DNAH6	3.87e-03	15	117	2	IPR004273
Domain	SIAH-type	SIAH1 SIAH2	4.41e-03	16	117	2	IPR013323
Domain	Disintegrin_CS	ADAM30 ADAM8	4.41e-03	16	117	2	IPR018358
Domain	Znf_RING	MARCHF6 RNF213 SIAH1 SIAH2 TRIM8 ARIH1 CNOT4	4.47e-03	326	117	7	IPR001841
Domain	ADAM_CR	ADAM30 ADAM8	5.58e-03	18	117	2	PF08516
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DYNC2H1 SYNE1 SPTA1 RNF213 SYNE2 EIF3B SSH2 DNAH6 PCNT	1.94e-08	187	120	9	26460568
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	IPO5 GTPBP4 MYH2 MYO1E NT5C3A HSPH1 ELP1 RNF213 DHX57 SPECC1 DIS3 ERLEC1 NKRF BLVRA MDN1 MYL9 GUSB DHCR24 SYNE2 PDS5A EIF3B	2.19e-08	1440	120	21	30833792
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PDS5B NWD1 ERCC6 ANK1 DOCK11 HSPH1 SLITRK4 DHX57 RRBP1 NEB SNX14 MDN1	1.66e-07	497	120	12	36774506
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	GTPBP4 HSPH1 DHX57 SIN3A RRBP1 NKRF KIAA1217 DHCR24 BRMS1	2.56e-07	253	120	9	29911972
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	IPO5 GTPBP4 HSPH1 GART NELFB ELP1 SIN3A DIS3 NKRF MDN1 WDR75 PDS5A EIF3B	3.44e-07	638	120	13	33239621
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IPO5 PDS5B GTPBP4 GART ELP1 DHX57 DIS3 NKRF MDN1 WDR75 SYNE2 PDS5A PCNT	4.46e-07	653	120	13	22586326
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	IPO5 PDS5B GTPBP4 SYNE1 CEP290 GART ELP1 RRBP1 SPECC1 NKRF MDN1 WDR75 SYNE2 EIF3B RAB5B PCNT	5.03e-07	1024	120	16	24711643
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B MYH2 GGNBP2 SYNE1 SPTA1 HSPH1 DHX57 RRBP1 NEB ERLEC1 ABCB4 MDN1 WDR75 RGPD3 SYNE2 CNKSR3 DNAH6 CCDC158 PCNT	5.24e-07	1442	120	19	35575683
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	IPO5 GTPBP4 SYNE1 NT5C3A ELP1 RNF213 DHX57 RRBP1 RMDN2 TTK NKRF BLVRA MDN1 WDR75 KIAA1217 SYNE2 PUS1 FASTKD3 PCNT	9.08e-07	1496	120	19	32877691
Pubmed	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.	SYNE1 CCDC141 CEP126 PCNT	9.40e-07	22	120	4	12812986
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	MYH2 SYNE1 HSPH1 GART RNF213 SIAH1 SIAH2 NEB MYL9 RGPD3 PYGM EIF3B MYL12B CNOT4	1.37e-06	844	120	14	25963833
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	IPO5 PDS5B GTPBP4 ATR DYNC2H1 SYNE1 HSPH1 GART ELP1 RRBP1 DIS3 MDN1 WDR75 DHCR24 PUS1 PDS5A EIF3B MGAM2	1.96e-06	1425	120	18	30948266
Pubmed	Differential regulation of PML-RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1.	SIAH1 SIAH2 ARIH1	2.22e-06	8	120	3	22037423
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	IPO5 PDS5B GTPBP4 ATR NELFB RNF213 SIN3A RRBP1 DIS3 NKRF BLVRA MDN1 PDS5A EIF3B ARIH1	2.30e-06	1014	120	15	32416067
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	IPO5 GTPBP4 HSPH1 GART RRBP1 SPECC1 TTK ERLEC1 BLVRA JAK1 MYL9 WDR75 GUSB SYNE2 PDS5A ARIH1 RAB5B	2.38e-06	1297	120	17	33545068
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CCDC186 SPECC1 TTK SNX29 WASHC5 SYNE2 CEP152 EIF3B	2.76e-06	251	120	8	29778605
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PDS5B RNF213 SIN3A DIS3 NKRF JAK1 WDR75 PUS1 PDS5A	3.03e-06	341	120	9	32971831
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	IPO5 HSPH1 GART ELP1 RRBP1 DIS3 EIF3B	3.10e-06	179	120	7	36261009
Pubmed	Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.	GTPBP4 GNE GART ELP1 SIN3A DIS3 NKRF	3.46e-06	182	120	7	32239614
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	B4GAT1 ATR DYNC2H1 NT5C3A HSPH1 RNF213 DIS3 BLVRA JAK1 NEO1 MDN1 GUSB DHCR24 PDS5A RAB5B	3.99e-06	1061	120	15	33845483
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B GTPBP4 ERCC6 GNE HSPH1 GART ELP1 DHX57 RRBP1 DIS3 NKRF BLVRA MDN1 WDR75 WASHC5 PDS5A EIF3B	4.18e-06	1353	120	17	29467282
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	IPO5 GTPBP4 MYO1E SYNE1 HSPH1 GART RRBP1 SPECC1 NSRP1 NKRF NEDD9 MYL9 EIF3B MYL12B	5.30e-06	949	120	14	36574265
Pubmed	N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1.	GTPBP4 RRBP1 BRMS1	6.48e-06	11	120	3	32853985
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	ATR CCDC186 DIS3 ERLEC1 NKRF BICD1 ALDOB PCNT	7.01e-06	285	120	8	32838362
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	GTPBP4 MYO1E GNE GART ELP1 RNF213 DHX57 DIS3 NSRP1 JAK1 ARIH1	7.95e-06	601	120	11	33658012
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 DOCK11 NELFB SPECC1 TTK MDN1 KIAA1217 SYNE2 CNKSR3 NR3C2 CEP152 SSH2 CNOT4	9.19e-06	861	120	13	36931259
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	IPO5 B4GAT1 MYO1E SYNE1 HSPH1 CEP290 SIAH1 FBXO11 RRBP1 SPECC1 BICD1 JAK1 SCG2 TRIM8 RAB5B PCNT	9.21e-06	1285	120	16	35914814
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	IPO5 SYNE1 ELP1 NEB CCDC141 NEDD9 NEO1 SYNE2 ZBTB40 PYGM	9.27e-06	497	120	10	23414517
Pubmed	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.	CEP290 TACC3 PCNT	1.12e-05	13	120	3	17920017
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	MYH2 MYO1E HSPH1 RRBP1 SPECC1 MYL9 KIAA1217 DHCR24 RGPD3 EIF3B MYL12B	1.16e-05	626	120	11	33644029
Pubmed	Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis.	MYO1E MYO1F	1.18e-05	2	120	2	30890704
Pubmed	Fine tuning of the UPR by the ubiquitin ligases Siah1/2.	SIAH1 SIAH2	1.18e-05	2	120	2	24809345
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	1.18e-05	2	120	2	11792814
Pubmed	Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina).	SIAH1 SIAH2	1.18e-05	2	120	2	8404535
Pubmed	Characterization of human homologs of the Drosophila seven in absentia (sina) gene.	SIAH1 SIAH2	1.18e-05	2	120	2	9403064
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	1.18e-05	2	120	2	24931616
Pubmed	Increased cation permeability in mutant mouse red blood cells with defective membrane skeletons.	ANK1 SPTA1	1.18e-05	2	120	2	7492791
Pubmed	PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.	PDS5B PDS5A	1.18e-05	2	120	2	31757807
Pubmed	The C-terminal putative nuclear localization sequence of breast cancer metastasis suppressor 1, BRMS1, is necessary for metastasis suppression.	SIN3A BRMS1	1.18e-05	2	120	2	23390556
Pubmed	Molecular pathology of inherited erythrocyte membrane disorders: hereditary spherocytosis and elliptocytosis.	ANK1 SPTA1	1.18e-05	2	120	2	1356891
Pubmed	Novel mutations in patients with hereditary red blood cell membrane disorders using next-generation sequencing.	ANK1 SPTA1	1.18e-05	2	120	2	28694211
Pubmed	Dimerization of hSiah proteins regulates their stability.	SIAH1 SIAH2	1.18e-05	2	120	2	16899216
Pubmed	Inhibition of Siah ubiquitin ligase function.	SIAH1 SIAH2	1.18e-05	2	120	2	18850011
Pubmed	PDS5A and PDS5B in Cohesin Function and Human Disease.	PDS5B PDS5A	1.18e-05	2	120	2	34070827
Pubmed	Identification and characterization of the murine ortholog (brms1) of breast-cancer metastasis suppressor 1 (BRMS1).	B4GAT1 BRMS1	1.18e-05	2	120	2	11774238
Pubmed	Generation and analysis of Siah2 mutant mice.	SIAH1 SIAH2	1.18e-05	2	120	2	14645526
Pubmed	Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: The role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene.	NKRF NOS2	1.18e-05	2	120	2	12381793
Pubmed	Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis.	SYNE2 PCNT	1.18e-05	2	120	2	30054381
Pubmed	SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.	SIAH1 SIAH2	1.18e-05	2	120	2	26654769
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	1.18e-05	2	120	2	22768332
Pubmed	PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome.	PDS5B PDS5A	1.18e-05	2	120	2	35986423
Pubmed	Resistance to malaria in ankyrin and spectrin deficient mice.	ANK1 SPTA1	1.18e-05	2	120	2	1832936
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	1.18e-05	2	120	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	1.18e-05	2	120	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	1.18e-05	2	120	2	24586179
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	1.18e-05	2	120	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	1.18e-05	2	120	2	31578382
Pubmed	Myo1f has an essential role in γδT intraepithelial lymphocyte adhesion and migration.	MYO1E MYO1F	1.18e-05	2	120	2	37207213
Pubmed	Novel role for mineralocorticoid receptors in control of a neuronal phenotype.	NR3C2 EMX1	1.18e-05	2	120	2	31745235
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	HSPH1 ELP1 SIN3A MDN1 RGPD3 EIF3B	1.59e-05	153	120	6	26365490
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	ERCC6 ATR CEP290 ELP1 TTC8 SYNE2 NR2E1	1.73e-05	233	120	7	32290105
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	ELP1 DHX57 DIS3 MDN1 WDR75 RAB2B EIF3B	1.93e-05	237	120	7	29564676
Pubmed	Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.	ABCB4 MYL9 MYL12B	2.17e-05	16	120	3	19794400
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	IPO5 GTPBP4 NT5C3A HSPH1 GART ELP1 RRBP1 DIS3 NKRF MDN1 WDR75 DHCR24 RGPD3 EIF3B RAB5B	2.93e-05	1257	120	15	37317656
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IPO5 MYO1E SYNE1 SPTA1 HSPH1 ELP1 DHX57 RRBP1 SPECC1 THBS4 CAMKV WASHC5 KIAA1217 SSH2 MYL12B DNAH6	3.42e-05	1431	120	16	37142655
Pubmed	Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.	SIAH1 SIAH2	3.53e-05	3	120	2	12810624
Pubmed	Pw1/Peg3 is a potential cell death mediator and cooperates with Siah1a in p53-mediated apoptosis.	SIAH1 SIAH2	3.53e-05	3	120	2	10681424
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	3.53e-05	3	120	2	16079285
Pubmed	O-GlcNAc transferase inhibits LPS-mediated expression of inducible nitric oxide synthase through an increased interaction with mSin3A in RAW264.7 cells.	SIN3A NOS2	3.53e-05	3	120	2	23824843
Pubmed	The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome.	SIAH1 SIAH2	3.53e-05	3	120	2	14645235
Pubmed	The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice.	SIAH1 SIAH2	3.53e-05	3	120	2	11884614
Pubmed	Pds5 Regulates Sister-Chromatid Cohesion and Chromosome Bi-orientation through a Conserved Protein Interaction Module.	PDS5B PDS5A	3.53e-05	3	120	2	28343969
Pubmed	Pathogenic variants of DYNC2H1, KIAA0556, and PTPN11 associated with hypothalamic hamartoma.	DYNC2H1 KATNIP	3.53e-05	3	120	2	31197031
Pubmed	Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells.	MYL9 MYL12B	3.53e-05	3	120	2	11942626
Pubmed	Normal p53 function in primary cells deficient for Siah genes.	SIAH1 SIAH2	3.53e-05	3	120	2	12417719
Pubmed	Spectrin's E2/E3 ubiquitin conjugating/ligating activity is diminished in sickle cells.	ANK1 SPTA1	3.53e-05	3	120	2	15929114
Pubmed	The substrate binding domains of human SIAH E3 ubiquitin ligases are now crystal clear.	SIAH1 SIAH2	3.53e-05	3	120	2	27776223
Pubmed	Changing patterns in cytoskeletal mRNA expression and protein synthesis during murine erythropoiesis in vivo.	ANK1 SPTA1	3.53e-05	3	120	2	1385865
Pubmed	Inherited hemolytic disease in mice: a review and update.	ANK1 SPTA1	3.53e-05	3	120	2	6763106
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	3.53e-05	3	120	2	10878022
Pubmed	Genetic susceptibility of intervertebral disc degeneration among young Finnish adults.	CILP KIAA1217	3.53e-05	3	120	2	22107760
Pubmed	Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.	PDS5B PDS5A	3.53e-05	3	120	2	24141881
Pubmed	Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO.	SIAH1 SIAH2	3.53e-05	3	120	2	25561546
Pubmed	Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling.	JAK1 NEO1	3.53e-05	3	120	2	37824022
Pubmed	Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit.	SIAH1 SIAH2	3.53e-05	3	120	2	21109632
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	3.53e-05	3	120	2	12408964
Pubmed	Ankyrin-independent membrane protein-binding sites for brain and erythrocyte spectrin.	ANK1 SPTA1	3.53e-05	3	120	2	2971657
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	3.53e-05	3	120	2	17462627
Pubmed	Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma.	SIAH1 SIAH2	3.53e-05	3	120	2	37078793
Pubmed	Investigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity.	SIAH1 SIAH2	3.53e-05	3	120	2	25202994
Pubmed	An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response.	SIAH1 SIAH2	3.53e-05	3	120	2	19043406
Pubmed	Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.	SIAH1 SIAH2	3.53e-05	3	120	2	17998205
Pubmed	The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.	SIAH1 SIAH2	3.53e-05	3	120	2	25528765
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	3.53e-05	3	120	2	33472039
Pubmed	The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6.	MARCHF6 DHCR24	3.53e-05	3	120	2	31904814
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	3.53e-05	3	120	2	25516977
Pubmed	Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation.	NEDD9 TTC8 PCNT	3.73e-05	19	120	3	30446775
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DOCK4 HSPH1 CEP290 TTK BICD1 WASHC5 KIAA1217 CNKSR3 PUS1 CEP152 CNOT4 PCNT	4.11e-05	853	120	12	28718761
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DYNC2H1 ELP1 TTK DIS3 MDN1 WDR75 DHCR24 CNKSR3 RAB2B PDS5A	5.00e-05	606	120	10	36538041
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	PDS5B GTPBP4 ANK1 HSPH1 GART RRBP1 TTK DIS3 NKRF BLVRA MDN1 WDR75 WASHC5 PUS1 EIF3B	5.03e-05	1318	120	15	30463901
Interaction	HCST interactions	PDS5B ATR NELFB RNF213 JAK1 TTC8 MDN1 PDS5A FASTKD3	3.86e-06	205	120	9	int:HCST
Interaction	FBXO22 interactions	PDS5B NWD1 ERCC6 ANK1 DOCK11 HSPH1 SLITRK4 DHX57 RRBP1 NEB SNX14 MDN1 ARIH1	2.03e-05	540	120	13	int:FBXO22
Interaction	GAN interactions	DYNC2H1 SYNE1 SPTA1 RNF213 SYNE2 EIF3B SSH2 DNAH6 PCNT	2.09e-05	253	120	9	int:GAN
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	9.34e-05	4	72	2	1252
GeneFamily	Myosins, class I	MYO1E MYO1F	4.31e-04	8	72	2	1097
GeneFamily	Myosin light chains\|EF-hand domain containing	MYL9 MYL12B	1.38e-03	14	72	2	657
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	DOCK4 PDS5B ITGA11 MYO1E SYNE1 HSPH1 TMTC1 ALDOB	1.63e-06	177	120	8	M39245
Coexpression	LAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES	DOCK4 MYO1E SYNE1 HSPH1 TMTC1 KIAA1217 ALDOB	3.32e-06	137	120	7	M39241
Coexpression	XIE_TRASTUZUMAB_CARDIOTOXICITY_CIRCRNA_GENES	SNX29 BLVRA SYNE2 CNKSR3	3.36e-05	40	120	4	MM17488
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DOCK4 PDS5B GALK2 ATR GNE MARCHF6 TTK BICD1 MDN1 SYNE2 PDS5A ARIH1 CNOT4 PCNT	3.83e-05	856	120	14	M4500
Coexpression	TRAVAGLINI_LUNG_CILIATED_CELL	NWD1 GALK2 RSPH4A MYO1E DYNC2H1 SYNE1 NT5C3A HSPH1 CEP290 CFAP43 TTC8 LRRIQ1 SYNE2 KATNIP CEP126 DNAH6	3.96e-05	1093	120	16	M41649
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN	DOCK4 PDS5B GALK2 BICD1 PCNT	4.28e-05	84	120	5	M13008
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	PDS5B GGNBP2 ATR DOCK11 SYNE1 MARCHF6 ELP1 RNF213 FBXO11 SIN3A ADAM8 NEDD9 JAK1 CD2 MYO1F PDS5A SSH2 ARIH1 MYL12B	4.76e-05	1492	120	19	M40023
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	IPO5 PDS5B DPP4 GGNBP2 ATR HSPH1 CEP290 SPECC1 TTK NSRP1 WASHC5 SYNE2	4.92e-05	656	120	12	M18979
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	ERCC6 HSPH1 SIN3A TTK DIS3 NSRP1 NKRF MDN1 WDR75 DENND2C	1.71e-05	333	118	10	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.39e-09	197	120	9	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NWD1 RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.39e-09	197	120	9	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.39e-09	197	120	9	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.39e-09	197	120	9	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.39e-09	197	120	9	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NWD1 RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.54e-09	198	120	9	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.98e-08	185	120	8	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	NWD1 RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	5.75e-08	194	120	8	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	5.75e-08	194	120	8	a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DYNC2H1 SYNE1 CFAP43 LRRIQ1 KIAA1217 SYNE2 CEP126 DNAH6	5.98e-08	195	120	8	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	5.98e-08	195	120	8	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DYNC2H1 SYNE1 CFAP43 LRRIQ1 KIAA1217 SYNE2 CEP126 DNAH6	5.98e-08	195	120	8	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NWD1 RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	5.98e-08	195	120	8	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	5.98e-08	195	120	8	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	5.98e-08	195	120	8	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.22e-08	196	120	8	a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.22e-08	196	120	8	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.22e-08	196	120	8	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.22e-08	196	120	8	a156840330630e518bc85633dded6f2c3ead3b30
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.22e-08	196	120	8	009e83c7251cf300be78b263634d233a8d972a68
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.22e-08	196	120	8	89ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.22e-08	196	120	8	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.47e-08	197	120	8	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 SYNE1 CEP290 CFAP43 LRRIQ1 SYNE2 CEP126 DNAH6	6.47e-08	197	120	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.47e-08	197	120	8	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RSPH4A DYNC2H1 SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.47e-08	197	120	8	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	CCDC186 HSPH1 CEP290 ERLEC1 LRRIQ1 SYNE2 TRIM8 CEP126	7.00e-08	199	120	8	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(09)_Interm._secr.>cil.\|World / shred by cell type by condition	NWD1 RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	7.27e-08	200	120	8	3305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	3.88e-07	169	120	7	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126	4.37e-07	172	120	7	187ae91148d293537afc77e10da2b64302322224
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	6.39e-07	182	120	7	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	Ciliated_cells-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	6.88e-07	184	120	7	07c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	7.39e-07	186	120	7	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	7.94e-07	188	120	7	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	RSPH4A DYNC2H1 SYNE1 CEP290 CFAP43 LRRIQ1 DNAH6	7.94e-07	188	120	7	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GNE DOCK11 CFAP43 BICD1 NEDD9 SYNE2 DNAH6	8.23e-07	189	120	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	8.53e-07	190	120	7	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	8.53e-07	190	120	7	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NWD1 DYNC2H1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	8.83e-07	191	120	7	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	RSPH4A SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	9.15e-07	192	120	7	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	multiciliated\|World / shred by cell class for turbinate	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 DNAH6	9.15e-07	192	120	7	0f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell	Bronchial_Brush\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	9.47e-07	193	120	7	3e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	9.47e-07	193	120	7	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	NWD1 DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	9.47e-07	193	120	7	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	RSPH4A SYNE1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	9.47e-07	193	120	7	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	9.47e-07	193	120	7	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	9.47e-07	193	120	7	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 DNAH6	9.80e-07	194	120	7	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	9.80e-07	194	120	7	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	9.80e-07	194	120	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD8_low_T\|normal_Pleural_Fluid / Location, Cell class and cell subclass	DPP4 SYNE1 RNF213 CD2 SYNE2 MYO1F MYL12B	9.80e-07	194	120	7	11eb317f66cbced1cedadd6daba443c4d832c49f
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	9.80e-07	194	120	7	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-06	195	120	7	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	T/NK_cells-CD8+_Naive_T_cell\|World / Lineage and Cell class	SYNE1 RNF213 JAK1 CD2 SYNE2 MYO1F MYL12B	1.01e-06	195	120	7	43f11068beea076e9caeb1572215c3f65c9308e1
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-06	195	120	7	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DYNC2H1 CFAP43 LRRIQ1 KIAA1217 SYNE2 CEP126 DNAH6	1.01e-06	195	120	7	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-06	195	120	7	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-06	195	120	7	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-06	195	120	7	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-06	195	120	7	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK4 MYO1E SYNE1 NEDD9 TMTC1 KIAA1217 SYNE2	1.01e-06	195	120	7	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-06	195	120	7	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	SYNE1 CFAP43 LRRIQ1 KIAA1217 SYNE2 CNKSR3 DNAH6	1.05e-06	196	120	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.05e-06	196	120	7	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.05e-06	196	120	7	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.05e-06	196	120	7	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.05e-06	196	120	7	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	SYNE1 CFAP43 LRRIQ1 KIAA1217 SYNE2 CNKSR3 DNAH6	1.05e-06	196	120	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.05e-06	196	120	7	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.09e-06	197	120	7	d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	CCDC186 NT5C3A CEP290 SPECC1 ERLEC1 MYL9 SYNE2	1.16e-06	199	120	7	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	CCDC186 HSPH1 CEP290 NSRP1 LRRIQ1 SYNE2 TRIM8	1.16e-06	199	120	7	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	CCDC186 HSPH1 SPECC1 NSRP1 NEDD9 MYL9 SYNE2	1.16e-06	199	120	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	(10)_Ciliated\|World / shred by cell type by condition	NWD1 RSPH4A SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	1.20e-06	200	120	7	1b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	RSPH4A DYNC2H1 SYNE1 CFAP43 LRRIQ1 CEP126 DNAH6	1.20e-06	200	120	7	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 DNAH6	1.20e-06	200	120	7	7cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	RSPH4A DYNC2H1 CFAP43 LRRIQ1 DHCR24 CEP126 DNAH6	1.20e-06	200	120	7	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NWD1 RSPH4A DYNC2H1 CCDC190 CFAP43 LRRIQ1 DNAH6	1.20e-06	200	120	7	8441e289377215a6877640946fe3f6de1f456502
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	3.07e-06	148	120	6	d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	3.07e-06	148	120	6	c8e93b87212f55774223caa385859c566fa1981f
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	3.86e-06	154	120	6	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	3.86e-06	154	120	6	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	MYH2 NEB CHRND DENND2C PYGM PCNT	4.01e-06	155	120	6	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	4.01e-06	155	120	6	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	4.01e-06	155	120	6	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 NT5C3A SPTA1 TAC4 ABCB4 DENND2C	5.17e-06	162	120	6	08ee7ae56e4927874515c47adc86dd845bf29a26
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	6.15e-06	167	120	6	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 ATR DYNC2H1 TAC4 CAMKV DENND2C	6.81e-06	170	120	6	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 DNAH6	7.05e-06	171	120	6	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 HSPH1 RNF213 CD2 SYNE2 ARIH1	7.05e-06	171	120	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 RNF213 CD2 DHCR24 SYNE2 MYO1F	8.31e-06	176	120	6	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	8.58e-06	177	120	6	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	8.86e-06	178	120	6	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A DYNC2H1 CCDC190 LRRIQ1 CEP126 DNAH6	9.44e-06	180	120	6	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	NWD1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.01e-05	182	120	6	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NWD1 RSPH4A DYNC2H1 CFAP43 LRRIQ1 DNAH6	1.10e-05	185	120	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NWD1 RSPH4A CCDC190 CFAP43 LRRIQ1 DNAH6	1.10e-05	185	120	6	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	NWD1 CCDC190 CFAP43 LRRIQ1 CEP126 DNAH6	1.10e-05	185	120	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	NWD1 RSPH4A CFAP43 LRRIQ1 CEP126 DNAH6	1.17e-05	187	120	6	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	RSPH4A DYNC2H1 CFAP43 LRRIQ1 CEP126 DNAH6	1.17e-05	187	120	6	2b4262c2e7c7830a976be168cee6eeb738d4feda
Drug	ICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A	FMO4 GALK2 GNE SIAH2 DIS3 BICD1 ZBTB40 PUS1 CEP152	6.35e-07	189	118	9	6997_DN
Disease	Seckel syndrome 1	ATR CEP152 PCNT	5.77e-08	3	115	3	C4551474
Disease	mean reticulocyte volume	PDS5B ANK1 ATR NT5C3A SPTA1 TAC4 NEB SPECC1 ABCB4 KIAA1217 ZBTB40 PUS1 TACC3	1.47e-05	799	115	13	EFO_0010701
Disease	Malignant neoplasm of breast	ERCC6 ANK1 B4GAT1 DYNC2H1 SYNE1 ELP1 CHRND CD2 SYNE2 TSPAN4 PUS1 FASTKD3 NOS2 NLRP8	7.68e-05	1074	115	14	C0006142
Disease	Seckel syndrome	ATR CEP152 PCNT	8.41e-05	22	115	3	C0265202
Disease	hereditary spherocytosis type 1 (implicated_via_orthology)	ANK1 SPTA1	8.99e-05	4	115	2	DOID:0110916 (implicated_via_orthology)
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	8.99e-05	4	115	2	cv:CN293514
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.49e-04	5	115	2	C1450051
Disease	hereditary spherocytosis (is_implicated_in)	ANK1 SPTA1	1.49e-04	5	115	2	DOID:12971 (is_implicated_in)
Disease	Cerebellar Ataxia	SYNE1 SNX14	1.49e-04	5	115	2	C0007758
Disease	Hereditary spherocytosis	ANK1 SPTA1	1.49e-04	5	115	2	cv:C0037889
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	1.49e-04	5	115	2	C0410190
Disease	Anemia, hereditary spherocytic hemolytic	ANK1 SPTA1	1.49e-04	5	115	2	C0221409
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	2.24e-04	6	115	2	cv:C0410189
Disease	MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE	NEB CHRND	2.24e-04	6	115	2	C1854678
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	2.24e-04	6	115	2	C0410189
Disease	Cholangitis, Sclerosing	ABCB4 NOS2	2.24e-04	6	115	2	C0008313
Disease	peritonitis (biomarker_via_orthology)	GUSB ALDOB	3.12e-04	7	115	2	DOID:8283 (biomarker_via_orthology)
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	3.12e-04	7	115	2	C0751337
Disease	Vasogenic Brain Edema	MYL9 NOS2	4.15e-04	8	115	2	C0750969
Disease	Cytotoxic Brain Edema	MYL9 NOS2	4.15e-04	8	115	2	C0750970
Disease	Hereditary spherocytosis	ANK1 SPTA1	4.15e-04	8	115	2	C0037889
Disease	Cytotoxic Cerebral Edema	MYL9 NOS2	4.15e-04	8	115	2	C0472388
Disease	Vasogenic Cerebral Edema	MYL9 NOS2	4.15e-04	8	115	2	C0472387
Disease	Primary sclerosing cholangitis	ABCB4 NOS2	4.15e-04	8	115	2	C0566602
Disease	Brain Edema	MYL9 NOS2	4.15e-04	8	115	2	C1527311
Disease	Cerebral Edema	MYL9 NOS2	4.15e-04	8	115	2	C0006114
Disease	cystic fibrosis (implicated_via_orthology)	ABCB4 ABCC12	5.32e-04	9	115	2	DOID:1485 (implicated_via_orthology)
Disease	cholestasis (implicated_via_orthology)	ABCB4 PYGM	5.32e-04	9	115	2	DOID:13580 (implicated_via_orthology)
Disease	hemolysis	ANK1 SPTA1 TAC4	8.25e-04	47	115	3	EFO_0009473
Disease	estradiol measurement	DHX57 FBXO11 JAK1 TTC8	9.20e-04	110	115	4	EFO_0004697
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	9.69e-04	12	115	2	DOID:11726 (implicated_via_orthology)
Disease	mean corpuscular hemoglobin concentration	PDS5B MYH2 ANK1 ATR SPTA1 SIAH1 TAC4 NEB SPECC1 NEO1 KIAA1217 PUS1	1.28e-03	1105	115	12	EFO_0004528
Disease	Bardet-Biedl syndrome 1 (disorder)	CEP290 TTC8	1.97e-03	17	115	2	C2936862
Disease	Moyamoya Disease	RNF213 PCNT	1.97e-03	17	115	2	C0026654
Disease	Bardet-Biedl syndrome	CEP290 TTC8	2.21e-03	18	115	2	cv:C0752166
Disease	obsolete_red blood cell distribution width	ANK1 ATR NT5C3A SPTA1 SIAH2 TAC4 ABCB4 NEO1 KIAA1217 SYNE2 ZBTB40 PUS1 PDS5A	2.29e-03	1347	115	13	EFO_0005192
Disease	red blood cell density measurement	ANK1 ATR NT5C3A SPTA1 SIAH1 TAC4 SPECC1 ZBTB40 PUS1 SSH2	2.36e-03	880	115	10	EFO_0007978
Disease	Chronic myeloproliferative disorder	ATR PCNT	2.47e-03	19	115	2	C1292778
Disease	Alzheimer disease, educational attainment	DPP4 SNX29 CAMKV TACC3 IP6K2	2.87e-03	247	115	5	EFO_0011015, MONDO_0004975
Disease	nucleotide measurement	ITGA11 JAK1 SYNE2	2.94e-03	73	115	3	EFO_0010513
Disease	Down syndrome (is_marker_for)	GART PCNT	3.31e-03	22	115	2	DOID:14250 (is_marker_for)
Disease	erythrocyte measurement	NT5C3A SPTA1 TAC4 SPECC1 ZBTB40	3.40e-03	257	115	5	EFO_0005047
Disease	Disproportionate short stature	DYNC2H1 DHCR24 PCNT	3.42e-03	77	115	3	C0878659

Protein segments in the cluster

Peptide	Gene	Start	Entry
LKEGYENFFDKLQQH	NT5C3A	181	Q9H0P0
IRQYHEEKETGQKIN	ERLEC1	131	Q96DZ1
ERLIRHLFQEKGYNK	CHRND	26	Q07001
KQLSQEKGRLHQLYE	CCDC186	351	Q7Z3E2
REKFLNNYLTRKQHE	CFAP43	1241	Q8NDM7
KHALEKQQLFEAYER	CEP152	696	O94986
DGYKLDKQHTFRVNL	EIF3B	251	P55884
QNQVEYEGLKHEIKR	BICD1	191	Q96G01
YVHLQGKEEFERQQK	NEDD9	631	Q14511
KEAENQHNKILYRQF	B4GAT1	386	O43505
QHNKILYRQFKQELK	B4GAT1	391	O43505
GIYVIHQAEGKKFNR	B4GALT4	156	O60513
HETLYQKDSQGKLFR	ALDOB	81	P05062
YGNIKLVKFLLQHQA	ANK1	711	P16157
LNLYQDGKHLKLSQR	CD2	156	P06729
KFNIDKEAGERQIYH	GYS2	226	P54840
HYKLALGQINIAKNL	GTPBP4	91	Q9BZE4
DIDEYKKNIHGNALR	SPECC1	296	Q5M775
NHVDKLYQKLNFRVV	ADAM8	231	P78325
GTIEEKIYHRQIFKQ	ERCC6	966	Q03468
YLKELGEQFVVRANH	NWD1	261	Q149M9
YQVRQVFAQKLHKGL	PDS5B	916	Q9NTI5
KQKDLSGFYRHLLNQ	NSRP1	176	Q9H0G5
YQVRQIFAQKLHKAL	PDS5A	926	Q29RF7
EIYRKIQQGLFDVHN	RAB2B	166	Q8WUD1
LVLRFVKGQFHEYQE	RAB5B	36	P61020
KNFQIEVQKGRYSLH	JAK1	496	P23458
QSLRFEHKLYAQVKQ	ARIH1	426	Q9Y4X5
QLKSQKRYHEDIFGA	NOS2	1116	P35228
RKQKELQYLQGHLVS	MDN1	246	Q9NU22
NVEQLVKFYKGNGHR	NR3C2	136	P08235
FVKELHDNGQKYLII	MGAM2	391	Q2M2H8
KHRNQYKFILLENLT	IP6K2	196	Q9UHH9
NREQYRQHLKEKFNK	GGNBP2	661	Q9H3C7
LNDYHKVVLRIGNNK	NLRP8	626	Q86W28
KLYVNRNLIFNGKLD	KATNIP	591	O60303
FEELGQRLQHYAKIA	HSPH1	716	Q92598
VRGQLYKHFDLERKN	CCDC190	6	Q86UF4
KGNFNYVEFTRILKH	MYL9	151	P24844
HYGNLKFKQKQREEQ	MYH2	361	Q9UKX2
QERKLNKRFNHEDYG	FMO4	256	P31512
QDVLIFKLYQRAKHV	GALK2	321	Q01415
YSQLGEKLEQLDHRK	NELFB	541	Q8WX92
QVRQFKRLYEHIKND	MARCHF6	866	O60337
HIKNDKYLVGQRLVN	MARCHF6	876	O60337
VLLYHREQEQSNKGK	MMAA	126	Q8IVH4
RAENFKQVEYLLIHG	DPP4	691	P27487
HLEKRYKIQFENNED	ELP1	481	O95163
VQHFLINILKKFYIG	ITGA11	181	Q9UKX5
IFGNQQQHYLDVIKR	IPO5	161	O00410
KIENRNLYGKLQHET	PCNT	696	O95613
KFKQHEEYIRNLHLQ	LRRIQ1	246	Q96JM4
GQNKELERYQKHLEN	ABCB4	271	P21439
LERYQKHLENAKEIG	ABCB4	276	P21439
DIKILQNYDNKHVRI	RGPD3	1381	A6NKT7
IKKGLIHYGRDNQNL	DYNC2H1	2611	Q8NCM8
EHVVYLLKKEQFGNQ	ADAM30	156	Q9UKF2
KQNIQEHLGFLQKLY	ATR	1666	Q13535
LFQRYVDEGLHFINK	DNAH6	1931	Q9C0G6
FHQKQKERIQDYEDI	CCDC141	771	Q6ZP82
NHDKNLFRKILAGDY	CAMKV	231	Q8NCB2
IKNLLIKHAFDTRYQ	DOCK11	1141	Q5JSL3
IHENIIKKLNARYNL	DOCK4	336	Q8N1I0
DKILQALHLQFGKQY	GNE	341	Q9Y223
KFAVIRHQQSLLYKE	CEP290	811	O15078
QNRYLQEKLHALEKQ	CEP290	2021	O15078
YVHEKGRGQFIENKI	FBXO11	506	Q86XK2
EHGYLKALIINQSFK	CEP126	586	Q9P2H0
QQLDFKQLLARYKGV	DHX57	796	Q6P158
KHVENYLKTNREGLE	DHCR24	306	Q15392
LEQYHLGLDQKRRKY	GUSB	566	P08236
IYRRKLQHFQEEKNK	CCDC152	211	Q4G0S7
FGVRYNCHQEIRLKK	DENND2C	46	Q68D51
EDYIRQFLNAGKHVL	BLVRA	81	P53004
FEKNHYVVGAERKQL	EMX1	211	Q04741
HEKQKFYLRQSVIDL	CCDC158	101	Q5M9N0
KQVALYFRGHKEENG	NR2E1	101	Q9Y466
KGNFNYIEFTRILKH	MYL12B	151	O14950
YEIAEKQKALFLQGH	RSPH4A	281	Q5TD94
NLIKYIERGAFNKLH	SLITRK4	141	Q8IW52
GQRYQALKAHAEEKL	TACC3	761	Q9Y6A5
KEVLNKHELQRFYSL	SNX29	91	Q8TEQ0
GAKRQSIHLEQKLYD	SYNE1	6371	Q8NF91
KHARLYQTLNEGKQL	SYNE2	4891	Q8WXH0
DERKQIHQIAQKYGL	NKRF	631	O15226
LKQAEELRQYKVLFH	NBPF19	86	A0A087WUL8
SYIHVKQIFKDNDRL	PLCZ1	36	Q86YW0
LGLVLERVHFEKYNQ	PUS1	331	Q9Y606
KEAIKQRHLQLLGYQ	FASTKD3	611	Q14CZ7
YFKIVKEHNLQVLGL	NEO1	386	Q92859
YLNQEKAEKGREHIA	SCG2	596	P13521
RQNLDHYNGKEFEKL	KIAA1217	976	Q5T5P2
HAINYVNKIKNRFQG	SIN3A	306	Q96ST3
KAFLEILHTYQKEQR	SIN3A	326	Q96ST3
LVLEKQEKYDGHQQF	SIAH1	191	Q8IUQ4
LVLEKQEKYEGHQQF	SIAH2	231	O43255
EGLQNKINYGHLFKE	RMDN2	276	Q96LZ7
GQLKYLEQQEGQLKH	IVL	281	P07476
NVRENILFGEKYDHQ	ABCC12	556	Q96J65
YKRIRDVTNNQEKHF	DIS3	106	Q9Y2L1
RNKYECELQGAKQHL	BRMS1	131	Q9HCU9
LVLRKLQQHQAGEYF	CILP	361	O75339
YVHKFEREKINGEQL	CNK3/IPCEF1	26	G9CGD6
YVHKFEREKINGEQL	CNKSR3	26	Q6P9H4
GKHQEYEQKLLQELY	CNOT4	231	O95628
YLQHIVEQKNGKERV	RNF213	4751	Q63HN8
RYLKNDGKVHLVVFN	THBS4	101	P35443
YPFLLRNKNHIEKNA	TTC8	221	Q8TAM2
RVHAQVQQFLKEGYL	WASHC5	336	Q12768
NFLKDQGRNKEAIYH	TMTC1	491	Q8IUR5
YREHVKEVQQLQGKI	RRBP1	766	Q9P2E9
NSLFDIQVKRIHEYK	PYGM	561	P11217
EYQGILLASKQRHNK	SSH2	441	Q76I76
KREEFQEYLQKLLQH	SNX14	656	Q9Y5W7
YFILGKHRQQQDEKL	WDR75	696	Q8IWA0
GQKLEDSYHLQVFKR	SPTA1	46	P02549
YGRDLQGVQNLLKKH	SPTA1	1741	P02549
RVINHKLYKNRVEFD	GART	861	P22102
KAFKYGSRLIQHENI	ZNF582	206	Q96NG8
IDRYAQQDLKKGLHL	TSPAN4	111	O14817
NKLQQHSDKIIRLYD	TTK	576	P33981
NQLKEEVRLQYEKLH	TRIM8	226	Q9BZR9
RKKAYQLEHTFQGLL	TAC4	81	Q86UU9
RKHYQLNFLLENEGV	ZBTB40	236	Q9NUA8
SRVKHQVEYLGLKEN	MYO1E	601	Q12965
VKHQVEYLGLKENIR	MYO1F	601	O00160
FEHAGQIQNERLYKE	NEB	4276	P20929