Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC32A1 TRPM4 ABCA2 SLC25A18 SLC7A13 CHRNA9 SLC35D2 SLC16A14 KCNJ10 SCN4A SLC22A10 SCN8A SLC15A5 SLCO1B3 SLC47A1 TRPM8 NMUR2 NIPAL3 SLCO1B1 CHRM5 ABCA8 SLC16A12 CHRND ATP6V0A2 SLC5A2 XPR1 SLC52A3

3.02e-1211809427GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC32A1 TRPM4 ABCA2 SLC25A18 SLC7A13 CHRNA9 SLC35D2 SLC16A14 KCNJ10 SCN4A SLC22A10 SCN8A SLC15A5 SLCO1B3 SLC47A1 TRPM8 ATP10B NMUR2 NIPAL3 SLCO1B1 CHRM5 ABCA8 SLC16A12 CHRND ATP6V0A2 SLC5A2 XPR1 SLC52A3

3.72e-1212899428GO:0005215
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC32A1 ABCA2 SLC25A18 SLC7A13 SLC35D2 SLC16A14 SLC22A10 SLC15A5 SLCO1B3 SLC47A1 SLCO1B1 ABCA8 SLC16A12 ATP6V0A2 SLC5A2 XPR1

7.26e-104779416GO:0022804
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC32A1 SLC25A18 SLC7A13 SLC35D2 SLC16A14 SLC22A10 SLC15A5 SLCO1B3 SLC47A1 SLCO1B1 SLC16A12 SLC5A2 XPR1

1.32e-092969413GO:0015291
GeneOntologyMolecularFunctionG protein-coupled receptor activity

TPRA1 OR4C3 GALR1 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 TAS2R36 NPSR1 OR4M1 OR4K5 NMUR2 TAS2R30 TAS2R46 CHRM5 OR10X1 OR52A1 OR4K14

2.43e-088849419GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TPRA1 OR4C3 GALR1 CHRNA9 OR4A8 OR6S1 OR4Q2 OR4A5 IL1R2 OR10H2 TAS2R36 NPSR1 OR4M1 OR4K5 RET NMUR2 TAS2R30 TAS2R46 CHRM5 OR10X1 OR52A1 OR4K14 CHRND

5.02e-0813539423GO:0004888
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC32A1 SLC25A18 SLC7A13 SLC35D2 SLC16A14 SLC22A10 SLCO1B3 SLC47A1 SLCO1B1 SLC16A12 SLC52A3

1.32e-072939411GO:0008514
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC32A1 SLC25A18 SLC7A13 SLC16A14 SLC22A10 SLCO1B3 SLC47A1 SLCO1B1 SLC16A12

5.77e-07207949GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC32A1 SLC25A18 SLC7A13 SLC16A14 SLC22A10 SLCO1B3 SLC47A1 SLCO1B1 SLC16A12

6.01e-07208949GO:0005342
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A SCN8A SLC47A1 TRPM8 NMUR2 NIPAL3 CHRM5 ATP6V0A2 SLC5A2 XPR1

2.43e-067589415GO:0015318
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC32A1 SLC16A14 SLC22A10 SLCO1B3 SLCO1B1 SLC16A12

4.19e-0690946GO:0008028
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A SCN8A SLC47A1 TRPM8 NMUR2 NIPAL3 CHRM5 CHRND ATP6V0A2 SLC5A2

4.22e-067939415GO:0015075
GeneOntologyMolecularFunctionolfactory receptor activity

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 OR4M1 OR4K5 OR10X1 OR52A1 OR4K14

5.76e-064319411GO:0004984
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A SCN8A SLC47A1 TRPM8 NIPAL3 CHRND ATP6V0A2 SLC5A2

1.37e-056649413GO:0008324
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

TRPM4 CHRNA9 KCNJ10 TRPM8 NMUR2 CHRM5 CHRND

3.56e-05193947GO:0015276
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A SCN8A SLC47A1 TRPM8 NIPAL3 ATP6V0A2 SLC5A2

3.77e-056279412GO:0022890
GeneOntologyMolecularFunctionligand-gated channel activity

TRPM4 CHRNA9 KCNJ10 TRPM8 NMUR2 CHRM5 CHRND

4.05e-05197947GO:0022834
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLC22A10 SLCO1B3 SLCO1B1

7.83e-0518943GO:0015347
GeneOntologyMolecularFunctionanandamide 8,9 epoxidase activity

CYP2D6 CYP3A4

1.31e-044942GO:0062187
GeneOntologyMolecularFunctionanandamide 11,12 epoxidase activity

CYP2D6 CYP3A4

1.31e-044942GO:0062188
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R36 TAS2R30 TAS2R46

2.72e-0427943GO:0033038
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPM4 CHRNA9 KCNJ10 SCN4A SCN8A TRPM8 NMUR2 CHRM5 CHRND

3.13e-04459949GO:0005216
GeneOntologyMolecularFunctionamino acid:proton symporter activity

SLC32A1 SLC25A18

3.25e-046942GO:0005280
GeneOntologyMolecularFunctionanandamide 14,15 epoxidase activity

CYP2D6 CYP3A4

3.25e-046942GO:0062189
GeneOntologyMolecularFunctionanandamide epoxidase activity

CYP2D6 CYP3A4

3.25e-046942GO:0062186
GeneOntologyMolecularFunctionlipid transporter activity

ABCA2 SLC22A10 SLCO1B3 ATP10B SLCO1B1 ABCA8

3.29e-04196946GO:0005319
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC32A1 SLC25A18 SLC7A13 SLC47A1

3.52e-0471944GO:0015179
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R36 TAS2R30 TAS2R46

4.98e-0433943GO:0008527
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TRPM4 CHRNA9 KCNJ10 TRPM8 CHRND

5.25e-04140945GO:0099094
GeneOntologyMolecularFunctionsymporter activity

SLC32A1 SLC25A18 SLC16A14 SLC15A5 SLC5A2

7.18e-04150945GO:0015293
GeneOntologyMolecularFunctionchannel activity

TRPM4 CHRNA9 KCNJ10 SCN4A SCN8A TRPM8 NMUR2 CHRM5 CHRND

8.23e-04525949GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPM4 CHRNA9 KCNJ10 SCN4A SCN8A TRPM8 NMUR2 CHRM5 CHRND

8.34e-04526949GO:0022803
GeneOntologyMolecularFunctiongated channel activity

TRPM4 CHRNA9 KCNJ10 TRPM8 NMUR2 CHRM5 CHRND

1.01e-03334947GO:0022836
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLCO1B3 SLC47A1 SLCO1B1

1.02e-0342943GO:0042887
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

CHRNA9 CHRM5 CHRND

1.09e-0343943GO:0005231
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM4 CHRNA9 KCNJ10 SCN4A SCN8A TRPM8 CHRND

1.18e-03343947GO:0005261
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC32A1 SLC25A18 SLC7A13 SLC47A1

1.53e-03105944GO:0015171
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM4 CHRNA9 KCNJ10 SCN4A SCN8A TRPM8 NIPAL3 SLC5A2

1.58e-03465948GO:0046873
GeneOntologyMolecularFunctionsodium channel activity

TRPM4 SCN4A SCN8A

1.89e-0352943GO:0005272
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B3 SLCO1B1

1.92e-0314942GO:0015132
GeneOntologyMolecularFunctionphosphatidate phosphatase activity

PLPPR4 PLPPR3

1.92e-0314942GO:0008195
GeneOntologyMolecularFunctionneuropeptide receptor activity

GALR1 NPSR1 NMUR2

2.00e-0353943GO:0008188
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO1B3 SLCO1B1

2.21e-0315942GO:0071714
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLCO1B3 SLCO1B1

2.52e-0316942GO:0035673
GeneOntologyMolecularFunctionacetylcholine-gated monoatomic cation-selective channel activity

CHRNA9 CHRND

2.85e-0317942GO:0022848
GeneOntologyMolecularFunctionlipid phosphatase activity

PLPPR4 PLPPR3

3.56e-0319942GO:0042577
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCA2 ATP10B

3.94e-0320942GO:0046624
GeneOntologyMolecularFunctionantiporter activity

SLC32A1 SLC7A13 SLC35D2 SLC47A1

4.12e-03138944GO:0015297
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLC22A10 SLCO1B3 SLCO1B1

4.95e-0373943GO:0170055
GeneOntologyMolecularFunctionacetylcholine receptor activity

CHRM5 CHRND

5.20e-0323942GO:0015464
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

CHRNA9 CHRM5 CHRND

5.34e-0375943GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

CHRNA9 CHRM5 CHRND

5.75e-0377943GO:0005230
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC32A1 SLC25A18

6.13e-0325942GO:0015295
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN4A SCN8A

6.62e-0326942GO:0005248
GeneOntologyMolecularFunctiontransaminase activity

BCAT1 KYAT1

6.62e-0326942GO:0008483
GeneOntologyMolecularFunctiontransferase activity, transferring nitrogenous groups

BCAT1 KYAT1

7.65e-0328942GO:0016769
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ATP10B

7.65e-0328942GO:0140326
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC32A1 SLC25A18

8.20e-0329942GO:0005416
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

TRPM4 SCN4A SCN8A SLC5A2

8.71e-03171944GO:0015081
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPM4 TRPM8

9.33e-0331942GO:0099604
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

HSD17B6 SDR42E1

1.05e-0233942GO:0033764
GeneOntologyBiologicalProcesssensory perception

LRAT OR4C3 CHRNA9 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 TAS2R36 KCNJ10 SCN8A OR4M1 TRPM8 OR4K5 NMUR2 TAS2R30 TAS2R46 OR10X1 OR52A1 OR4K14 SLC52A3 RNF170

2.46e-0910729522GO:0007600
GeneOntologyBiologicalProcessorganic anion transport

SLC32A1 SLC25A18 NF1 SLC7A13 SLC35D2 SLC16A14 KCNJ10 SLC22A10 SLCO1B3 SLC47A1 NMUR2 ARHGEF11 SLCO1B1 SLC16A12 SLC52A3

1.32e-085159515GO:0015711
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 TAS2R36 OR4M1 OR4K5 TAS2R30 TAS2R46 OR10X1 OR52A1 OR4K14

4.70e-084859514GO:0050907
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC32A1 SLC25A18 NF1 SLC7A13 SLC35D2 SLC16A14 KCNJ10 SLCO1B3 SLC47A1 NMUR2 ARHGEF11 SLCO1B1 SLC16A12

4.99e-084109513GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC32A1 SLC25A18 NF1 SLC7A13 SLC35D2 SLC16A14 KCNJ10 SLCO1B3 SLC47A1 NMUR2 ARHGEF11 SLCO1B1 SLC16A12

5.29e-084129513GO:0015849
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR4C3 CHRNA9 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 TAS2R36 OR4M1 OR4K5 TAS2R30 TAS2R46 OR10X1 OR52A1 OR4K14

6.58e-085829515GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 TAS2R36 OR4M1 OR4K5 TAS2R30 TAS2R46 OR10X1 OR52A1 OR4K14

1.22e-075249514GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 TAS2R36 OR4M1 OR4K5 TAS2R30 TAS2R46 OR10X1 OR52A1 OR4K14

2.05e-075479514GO:0007606
GeneOntologyBiologicalProcessL-amino acid transport

SLC32A1 SLC25A18 NF1 SLC7A13 KCNJ10 SLC47A1 ARHGEF11

6.71e-07108957GO:0015807
GeneOntologyBiologicalProcessdetection of stimulus

OR4C3 CHRNA9 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 TAS2R36 OR4M1 OR4K5 TAS2R30 TAS2R46 OR10X1 OR52A1 OR4K14

1.03e-067229515GO:0051606
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

TPRA1 OR4C3 GALR1 OR4A8 OR6S1 PLPPR4 OR4Q2 OR4A5 OR10H2 TAS2R36 NPSR1 OR4M1 OR4K5 NMUR2 TAS2R30 TAS2R46 ARHGEF11 CHRM5 OR10X1 OR52A1 OR4K14

1.13e-0613959521GO:0007186
GeneOntologyBiologicalProcessL-glutamate import

SLC25A18 NF1 SLC7A13 KCNJ10 ARHGEF11

2.20e-0646955GO:0051938
GeneOntologyBiologicalProcessacidic amino acid transport

SLC32A1 SLC25A18 NF1 SLC7A13 KCNJ10 ARHGEF11

2.48e-0684956GO:0015800
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 OR4M1 OR4K5 OR10X1 OR52A1 OR4K14

4.82e-064329511GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 OR4M1 OR4K5 OR10X1 OR52A1 OR4K14

9.66e-064659511GO:0007608
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC25A18 SLC7A13 SLC35D2 KCNJ10 SLC47A1 ARHGEF11 SLC16A12

1.04e-05163957GO:1905039
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC25A18 SLC7A13 SLC35D2 KCNJ10 SLC47A1 ARHGEF11 SLC16A12

1.22e-05167957GO:1903825
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC32A1 SLC25A18 SLC7A13 KCNJ10 SLC47A1 ARHGEF11

1.95e-05120956GO:0003333
GeneOntologyBiologicalProcessL-glutamate transmembrane transport

SLC25A18 SLC7A13 KCNJ10 ARHGEF11

1.98e-0535954GO:0015813
GeneOntologyBiologicalProcessamino acid transport

SLC32A1 SLC25A18 NF1 SLC7A13 KCNJ10 SLC47A1 ARHGEF11

3.32e-05195957GO:0006865
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A SLC22A10 NPSR1 SCN8A SLCO1B3 SLC47A1 TRPM8 NMUR2 NIPAL3 SLCO1B1 CHRND ATP6V0A2 SLC5A2

4.86e-0513749518GO:0006811
GeneOntologyBiologicalProcesslocomotory behavior

APH1B SELENOP ABCA2 MYG1 CWH43 KCNJ10 SCN8A RNF170

5.05e-05284958GO:0007626
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC25A18 SLC7A13 KCNJ10 SLC47A1 ARHGEF11

5.11e-0587955GO:1902475
GeneOntologyBiologicalProcessbehavior

APH1B TRPM4 SELENOP ABCA2 MYG1 NF1 CWH43 KCNJ10 NPSR1 SCN8A NMUR2 NIPAL3 SDK1 RNF170

5.60e-058919514GO:0007610
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A NPSR1 SCN8A SLC47A1 TRPM8 NMUR2 NIPAL3 ATP6V0A2 SLC5A2 XPR1

6.08e-0510179515GO:0098660
GeneOntologyBiologicalProcessretinol metabolic process

LRAT CYP2D6 CYP3A4 HSD17B6

1.04e-0453954GO:0042572
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A NPSR1 SCN8A SLC47A1 TRPM8 NMUR2 NIPAL3 CHRND ATP6V0A2 SLC5A2

1.69e-0411159515GO:0034220
GeneOntologyBiologicalProcesswalking behavior

CWH43 KCNJ10 SCN8A RNF170

1.69e-0460954GO:0090659
GeneOntologyBiologicalProcessalkaloid catabolic process

CYP2D6 CYP3A4

2.08e-045952GO:0009822
GeneOntologyBiologicalProcessdicarboxylic acid transport

SLC25A18 NF1 SLC7A13 KCNJ10 ARHGEF11

2.34e-04120955GO:0006835
GeneOntologyBiologicalProcessmembrane depolarization

TRPM4 CHRNA9 SCN4A SCN8A CHRND

2.43e-04121955GO:0051899
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A NPSR1 SCN8A SLC47A1 TRPM8 NIPAL3 ATP6V0A2 SLC5A2

3.06e-049229513GO:0098662
GeneOntologyBiologicalProcessmonoterpenoid metabolic process

CYP2D6 CYP3A4

3.11e-046952GO:0016098
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A NPSR1 SCN8A SLC47A1 TRPM8 NIPAL3 ATP6V0A2 SLC5A2

3.76e-049429513GO:0098655
GeneOntologyBiologicalProcessisoprenoid metabolic process

LRAT CYP2D6 CYP3A4 HSD17B6 ALG8

5.41e-04144955GO:0006720
GeneOntologyBiologicalProcesslipid transport

LRAT ABCA2 GALR1 PLPPR4 SLCO1B3 ATP10B NMUR2 SLCO1B1 ABCA8

5.44e-04506959GO:0006869
GeneOntologyBiologicalProcessmembrane depolarization during action potential

TRPM4 SCN4A SCN8A

6.05e-0436953GO:0086010
GeneOntologyBiologicalProcessphospholipid metabolic process

LRAT ABCA2 CWH43 PLPPR4 PLPPR3 MBOAT2 CHRM5 ABCA8

6.13e-04410958GO:0006644
GeneOntologyBiologicalProcessalkaloid metabolic process

CYP2D6 CYP3A4

7.40e-049952GO:0009820
GeneOntologyBiologicalProcessretinoid metabolic process

LRAT CYP2D6 CYP3A4 HSD17B6

7.64e-0489954GO:0001523
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC32A1 TRPM4 SLC25A18 CHRNA9 KCNJ10 SCN4A NPSR1 SCN8A SLC47A1 TRPM8 NIPAL3 CHRND ATP6V0A2 SLC5A2

8.17e-0411579514GO:0006812
GeneOntologyBiologicalProcessditerpenoid metabolic process

LRAT CYP2D6 CYP3A4 HSD17B6

9.38e-0494954GO:0016101
GeneOntologyBiologicalProcessphospholipid dephosphorylation

PLPPR4 PLPPR3 CHRM5

1.09e-0344953GO:0046839
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of bitter taste

TAS2R36 TAS2R30 TAS2R46

1.09e-0344953GO:0001580
GeneOntologyBiologicalProcesspigment catabolic process

SLCO1B3 SLCO1B1

1.12e-0311952GO:0046149
GeneOntologyBiologicalProcessheme catabolic process

SLCO1B3 SLCO1B1

1.12e-0311952GO:0042167
GeneOntologyBiologicalProcesslipid localization

LRAT ABCA2 GALR1 PLPPR4 SLCO1B3 ATP10B NMUR2 SLCO1B1 ABCA8

1.18e-03565959GO:0010876
GeneOntologyCellularComponenttransporter complex

TRPM4 ABCA2 CATSPERE CHRNA9 KCNJ10 SCN4A SCN8A ATP10B CHRND ATP6V0A2

2.00e-045509510GO:1990351
GeneOntologyCellularComponentsodium channel complex

TRPM4 SCN4A SCN8A

3.05e-0429953GO:0034706
GeneOntologyCellularComponenttransmembrane transporter complex

TRPM4 ABCA2 CATSPERE CHRNA9 KCNJ10 SCN4A SCN8A CHRND ATP6V0A2

6.26e-04523959GO:1902495
GeneOntologyCellularComponentbasolateral plasma membrane

KCNJ10 SLC22A10 SLCO1B3 SLC47A1 SLCO1B1 ABCA8 SLC16A12

6.45e-04320957GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

KCNJ10 SLC22A10 SLCO1B3 SLC47A1 SLCO1B1 ABCA8 SLC16A12

1.16e-03354957GO:0009925
GeneOntologyCellularComponentbasal part of cell

KCNJ10 SLC22A10 SLCO1B3 SLC47A1 SLCO1B1 ABCA8 SLC16A12

1.69e-03378957GO:0045178
GeneOntologyCellularComponentmonoatomic ion channel complex

TRPM4 CATSPERE CHRNA9 KCNJ10 SCN4A SCN8A CHRND

1.69e-03378957GO:0034702
GeneOntologyCellularComponentendoplasmic reticulum membrane

APH1B LRAT SCAP CYP2D6 CYP3A4 JKAMP ALG8 UBAC2 TRPM8 ATP10B BFAR UBIAD1 MBOAT2 RNF170

2.07e-0312939514GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

APH1B LRAT SCAP CYP2D6 CYP3A4 JKAMP ALG8 UBAC2 TRPM8 ATP10B BFAR UBIAD1 MBOAT2 RNF170

2.16e-0312999514GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

APH1B LRAT SCAP CYP2D6 CYP3A4 JKAMP ALG8 UBAC2 TRPM8 ATP10B BFAR UBIAD1 MBOAT2 RNF170

2.62e-0313279514GO:0042175
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN4A SCN8A

2.66e-0317952GO:0001518
GeneOntologyCellularComponentacetylcholine-gated channel complex

CHRNA9 CHRND

2.98e-0318952GO:0005892
HumanPhenoBilirubinuria

SLCO1B3 SLCO1B1

2.13e-052242HP:0031811
DomainGPCR_Rhodpsn_7TM

OR4C3 GALR1 OR6S1 OR4A5 OR10H2 NPSR1 OR4M1 OR4K5 NMUR2 CHRM5 OR10X1 OR52A1 OR4K14

1.88e-056709013IPR017452
Domain7tm_1

OR4C3 GALR1 OR6S1 OR4A5 OR10H2 NPSR1 OR4M1 OR4K5 NMUR2 CHRM5 OR10X1 OR52A1 OR4K14

2.09e-056779013PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4C3 GALR1 OR6S1 OR4A5 OR10H2 NPSR1 OR4M1 OR4K5 NMUR2 CHRM5 OR10X1 OR52A1 OR4K14

2.37e-056859013PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4C3 GALR1 OR6S1 OR4A5 OR10H2 NPSR1 OR4M1 OR4K5 NMUR2 CHRM5 OR10X1 OR52A1 OR4K14

2.59e-056919013PS50262
DomainGPCR_Rhodpsn

OR4C3 GALR1 OR6S1 OR4A5 OR10H2 NPSR1 OR4M1 OR4K5 NMUR2 CHRM5 OR10X1 OR52A1 OR4K14

2.63e-056929013IPR000276
DomainMFS_dom

SLC16A14 SLC22A10 SLC15A5 SLCO1B3 SLCO1B1 SLC16A12

4.63e-05134906IPR020846
DomainOlfact_rcpt

OR4C3 OR6S1 OR4A5 OR10H2 OR4M1 OR4K5 OR10X1 OR52A1 OR4K14

1.16e-04393909IPR000725
DomainMFS

SLC16A14 SLC22A10 SLCO1B3 SLCO1B1 SLC16A12

1.75e-04108905PS50850
DomainNa_channel_asu

SCN4A SCN8A

1.01e-0310902IPR001696
DomainNa_trans_assoc

SCN4A SCN8A

1.01e-0310902IPR010526
DomainNa_trans_assoc

SCN4A SCN8A

1.01e-0310902PF06512
DomainABC_A

ABCA2 ABCA8

1.47e-0312902IPR026082
DomainOA_transporter

SLCO1B3 SLCO1B1

1.47e-0312902IPR004156
DomainOATP

SLCO1B3 SLCO1B1

1.47e-0312902PF03137
DomainIon_trans_dom

TRPM4 SCN4A SCN8A TRPM8

2.25e-03114904IPR005821
DomainIon_trans

TRPM4 SCN4A SCN8A TRPM8

2.25e-03114904PF00520
DomainNicotinic_acetylcholine_rcpt

CHRNA9 CHRND

2.64e-0316902IPR002394
Domain-

PLPPR4 PLPPR3

3.34e-03189021.20.144.10
DomainacidPPc

PLPPR4 PLPPR3

3.34e-0318902SM00014
DomainP_Acid_Pase_2/haloperoxidase

PLPPR4 PLPPR3

4.12e-0320902IPR000326
DomainPAP2

PLPPR4 PLPPR3

4.12e-0320902PF01569
Domain-

CHRNA9 CHRND

5.44e-03239021.20.120.370
DomainAcetylcholine_rcpt_TM

CHRNA9 CHRND

5.44e-0323902IPR027361
DomainMFS_1

SLC16A14 SLC22A10 SLC16A12

6.12e-0377903PF07690
DomainMFS

SLC16A14 SLC22A10 SLC16A12

6.12e-0377903IPR011701
DomainTAS2R

TAS2R30 TAS2R46

6.92e-0326902PF05296
DomainT2R

TAS2R30 TAS2R46

6.92e-0326902IPR007960
PathwayREACTOME_SENSORY_PERCEPTION

LRAT TRPM4 OR4C3 CHRNA9 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 HSD17B6 OR4M1 OR4K5 TAS2R30 TAS2R46 EPB41L3 OR10X1 OR52A1 OR4K14

2.00e-096367218M41834
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC32A1 TRPM4 ABCA2 SLC25A18 SLC35D2 SLCO1B3 SLC47A1 TRPM8 ATP10B NIPAL3 SLCO1B1 ABCA8 ATP6V0A2 SLC5A2

7.29e-066817214MM14985
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 OR4M1 OR4K5 OR10X1 OR52A1 OR4K14

7.93e-064177211M4072
PathwayREACTOME_ATORVASTATIN_ADME

CYP3A4 SLCO1B3 SLCO1B1

1.05e-059723M45020
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC32A1 TRPM4 ABCA2 SLC25A18 SLC35D2 SLCO1B3 SLC47A1 TRPM8 ATP10B NIPAL3 SLCO1B1 ABCA8 ATP6V0A2 SLC5A2

1.76e-057367214M27287
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

CYP2D6 CYP3A4 SLCO1B1

4.47e-0514723M39328
PathwayREACTOME_ATORVASTATIN_ADME

CYP3A4 SLCO1B3 SLCO1B1

5.56e-0515723MM15697
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR4C3 OR6S1 OR4A5 OR10H2 OR4M1 OR4K5 OR10X1 OR52A1 OR4K14

1.55e-04389729M14091
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC32A1 SLC25A18 SLC35D2 SLCO1B3 SLC47A1 SLCO1B1 SLC5A2

2.07e-04238727MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC32A1 SLC25A18 SLC35D2 SLCO1B3 SLC47A1 SLCO1B1 SLC5A2

2.73e-04249727M5988
PathwayREACTOME_BIOSYNTHESIS_OF_MARESIN_LIKE_SPMS

CYP2D6 CYP3A4

3.81e-046722M27909
PathwayREACTOME_SENSORY_PERCEPTION

LRAT OR10H2 HSD17B6 TAS2R30 TAS2R46 OR10X1

4.14e-04190726MM15687
PathwayREACTOME_BIOSYNTHESIS_OF_MARESINS

CYP2D6 CYP3A4

7.06e-048722M27891
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC35D2 SLCO1B3 SLCO1B1

1.18e-0341723MM15075
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC35D2 SLCO1B3 SLCO1B1

1.36e-0343723M881
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1B3 SLCO1B1

1.37e-0311722M930
PathwayREACTOME_GPCR_LIGAND_BINDING

GALR1 PLPPR4 NPSR1 PLPPR3 NMUR2 TAS2R30 TAS2R46 CHRM5

1.52e-03430728MM15160
PathwayWP_IRINOTECAN_PATHWAY

CYP3A4 SLCO1B1

1.64e-0312722M39611
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1B3 SLCO1B1

1.64e-0312722MM15476
PathwayREACTOME_BIOSYNTHESIS_OF_MARESINS

CYP2D6 CYP3A4

1.64e-0312722MM15616
PathwayWP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS

SLCO1B3 SLCO1B1

1.64e-0312722M48096
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TRPM4 TAS2R30 TAS2R46

1.76e-0347723M42524
PathwayWP_SULFATASE_AND_AROMATASE_PATHWAY

SLCO1B3 SLCO1B1

2.25e-0314722M48085
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

PLPPR4 PLPPR3

2.25e-0314722M27331
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

PLPPR4 PLPPR3

2.25e-0314722MM15062
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNA9 CHRND

2.25e-0314722M757
PathwayREACTOME_DRUG_ADME

CYP2D6 CYP3A4 SLCO1B3 SLCO1B1

2.32e-03109724M45012
PathwayREACTOME_GPCR_LIGAND_BINDING

GALR1 PLPPR4 NPSR1 PLPPR3 NMUR2 TAS2R30 TAS2R46 CHRM5

2.42e-03463728M507
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNA9 CHRND

2.59e-0315722MM14704
PathwayWP_FATTY_ACID_OMEGAOXIDATION

CYP2D6 CYP3A4

2.59e-0315722M39717
PathwayREACTOME_HEME_DEGRADATION

SLCO1B3 SLCO1B1

2.59e-0315722M27060
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SLC32A1 CYP2D6 CYP3A4 SCN4A SCN8A KYAT1 SLC52A3

2.64e-03367727M48346
Pubmed

The SLCO1B1*5 genetic variant is associated with statin-induced side effects.

CYP2D6 CYP3A4 SLCO1B1

2.03e-07596319833260
Pubmed

Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.

ABCA2 CYP2D6 CYP3A4 SLCO1B1

2.55e-072096421072184
Pubmed

The human olfactory receptor gene family.

OR4C3 OR4A8 OR6S1 OR4Q2 OR4A5 OR10H2 OR4M1 OR4K5 OR10X1 OR52A1 OR4K14

3.12e-07541961114983052
Pubmed

Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity.

CYP3A4 SLCO1B3 SLCO1B1

4.05e-07696320212519
Pubmed

Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.

SCAP CYP2D6 CYP3A4 SLCO1B1

1.62e-063196420031551
Pubmed

Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

SLCO1B3 SLCO1B1

7.54e-06296218314419
Pubmed

OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.

SLCO1B3 SLCO1B1

7.54e-06296221691816
Pubmed

Pharmacogenomics of oxycodone: a narrative literature review.

CYP2D6 CYP3A4

7.54e-06296233728947
Pubmed

Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes.

NF1 RET

7.54e-06296224361808
Pubmed

Interaction study of engeletin toward cytochrome P450 3A4 and 2D6 by multi-spectroscopy and molecular docking.

CYP2D6 CYP3A4

7.54e-06296234481255
Pubmed

Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.

SLCO1B3 SLCO1B1

7.54e-06296228063966
Pubmed

Relationship of cytochrome P450 pharmacogenetics to the effects of yohimbine on gastrointestinal transit and catecholamines in healthy subjects.

CYP2D6 CYP3A4

7.54e-06296218433425
Pubmed

Effect of cyp2d6*10 allele on the pharmacokinetics of loratadine in chinese subjects.

CYP2D6 CYP3A4

7.54e-06296215932952
Pubmed

Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.

SLCO1B3 SLCO1B1

7.54e-06296222240838
Pubmed

Association of CYP2D6*10, OATP1B1 A388G, and OATP1B1 T521C polymorphisms and overall survival of breast cancer patients after tamoxifen therapy.

CYP2D6 SLCO1B1

7.54e-06296225701109
Pubmed

Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.

SLCO1B3 SLCO1B1

7.54e-06296229944058
Pubmed

Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator.

CYP2D6 CYP3A4

7.54e-06296220007670
Pubmed

Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.

SLCO1B3 SLCO1B1

7.54e-06296217412826
Pubmed

SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.

SLCO1B3 SLCO1B1

7.54e-06296236964102
Pubmed

Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.

SLCO1B3 SLCO1B1

7.54e-06296223340295
Pubmed

How a concentration-effect analysis of data from the eliglustat thorough electrocardiographic study was used to support dosing recommendations.

CYP2D6 CYP3A4

7.54e-06296233012655
Pubmed

Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.

SLCO1B3 SLCO1B1

7.54e-06296229777022
Pubmed

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

SLCO1B3 SLCO1B1

7.54e-06296226191226
Pubmed

Inhibition of human cytochrome P450 enzymes 3A4 and 2D6 by β-carboline alkaloids, harmine derivatives.

CYP2D6 CYP3A4

7.54e-06296221433154
Pubmed

The Influence of the CYP3A4*22 Polymorphism and CYP2D6 Polymorphisms on Serum Concentrations of Aripiprazole, Haloperidol, Pimozide, and Risperidone in Psychiatric Patients.

CYP2D6 CYP3A4

7.54e-06296225868121
Pubmed

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.

SLCO1B3 SLCO1B1

7.54e-06296222771883
Pubmed

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

SLCO1B3 SLCO1B1

7.54e-06296224194513
Pubmed

Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.

SLCO1B3 SLCO1B1

7.54e-06296218180273
Pubmed

Gene-gene-environment interactions between drugs, transporters, receptors, and metabolizing enzymes: Statins, SLCO1B1, and CYP3A4 as an example.

CYP3A4 SLCO1B1

7.54e-06296223436703
Pubmed

Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1.

CYP3A4 SLCO1B1

7.54e-06296230862625
Pubmed

Structure of human drug transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

7.54e-06296237723174
Pubmed

Combined effects of itraconazole and CYP2D6*10 genetic polymorphism on the pharmacokinetics and pharmacodynamics of haloperidol in healthy subjects.

CYP2D6 CYP3A4

7.54e-06296216633141
Pubmed

Interaction of buprenorphine and its metabolite norbuprenorphine with cytochromes p450 in vitro.

CYP2D6 CYP3A4

7.54e-06296212756210
Pubmed

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

SLCO1B3 SLCO1B1

7.54e-06296224855184
Pubmed

Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE.

CYP2D6 CYP3A4

7.54e-06296215770075
Pubmed

Probabilistic prediction of the human CYP3A4 and CYP2D6 metabolism sites.

CYP2D6 CYP3A4

7.54e-06296219937844
Pubmed

Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.

SLCO1B3 SLCO1B1

7.54e-06296226474710
Pubmed

Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.

SLCO1B3 SLCO1B1

7.54e-06296225578040
Pubmed

Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib.

SLCO1B3 SLCO1B1

7.54e-06296223670789
Pubmed

Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.

SLCO1B3 SLCO1B1

7.54e-06296224989890
Pubmed

A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone.

CYP2D6 CYP3A4

7.54e-06296223277250
Pubmed

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.

SLCO1B3 SLCO1B1

7.54e-06296217496208
Pubmed

Rotor Syndrome

SLCO1B3 SLCO1B1

7.54e-06296223236639
Pubmed

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver.

SLCO1B3 SLCO1B1

7.54e-06296227098745
Pubmed

Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.

SLCO1B3 SLCO1B1

7.54e-06296224740327
Pubmed

Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.

SLCO1B3 SLCO1B1

7.54e-06296221719246
Pubmed

Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.

SLCO1B3 SLCO1B1

7.54e-06296220877131
Pubmed

Impact of CYP2D6 and CYP3A4 genetic polymorphism on combined cholinesterase inhibitors and memantine treatment in mild to moderate Alzheimer's disease.

CYP2D6 CYP3A4

7.54e-06296224107805
Pubmed

Effect of Curcuma longa on CYP2D6- and CYP3A4-mediated metabolism of dextromethorphan in human liver microsomes and healthy human subjects.

CYP2D6 CYP3A4

7.54e-06296224510399
Pubmed

Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro.

CYP2D6 CYP3A4

7.54e-06296230658716
Pubmed

Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

7.54e-06296216534140
Pubmed

UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3.

SLCO1B3 SLCO1B1

7.54e-06296231299240
Pubmed

Functional maturation of cytochromes P450 3A4 and 2D6 relies on GAPDH- and Hsp90-Dependent heme allocation.

CYP2D6 CYP3A4

7.54e-06296238199567
Pubmed

Genetic susceptibility to tardive dyskinesia in chronic schizophrenia subjects: III. Lack of association of CYP3A4 and CYP2D6 gene polymorphisms.

CYP2D6 CYP3A4

7.54e-06296215820320
Pubmed

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

SLCO1B3 SLCO1B1

7.54e-06296223886114
Pubmed

OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.

SLCO1B3 SLCO1B1

7.54e-06296221787759
Pubmed

Exploration of catalytic properties of CYP2D6 and CYP3A4 through metabolic studies of levorphanol and levallorphan.

CYP2D6 CYP3A4

7.54e-06296219797609
Pubmed

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

7.54e-06296218321482
Pubmed

Mutation in the Monocarboxylate Transporter 12 Gene Affects Guanidinoacetate Excretion but Does Not Cause Glucosuria.

SLC16A12 SLC5A2

7.54e-06296226376857
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

ABCA2 CYP2D6 CYP3A4 SLCO1B3 SLCO1B1 ABCA8

1.65e-0519396619343046
Pubmed

Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions.

SLCO1B3 SLCO1B1

2.26e-05396231047942
Pubmed

Candidate-Gene Study of Functional Polymorphisms in SLCO1B1 and CYP3A4/5 and the Cholesterol-Lowering Response to Simvastatin.

CYP3A4 SLCO1B1

2.26e-05396228482130
Pubmed

Assessment of the stereoselective metabolism of methaqualone in man by capillary electrophoresis.

CYP2D6 CYP3A4

2.26e-05396212900872
Pubmed

Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent.

SLCO1B3 SLCO1B1

2.26e-05396226146841
Pubmed

Metabolizing profile of the cytochrome pathway CYP2D6, CYP3A4 and the ABCB 1 transporter in Spanish patients affected by Gaucher disease.

CYP2D6 CYP3A4

2.26e-05396234058179
Pubmed

Combinatorial Pharmacogenomic Algorithm is Predictive of Citalopram and Escitalopram Metabolism in Patients with Major Depressive Disorder.

CYP2D6 CYP3A4

2.26e-05396232485484
Pubmed

SLCO1B1, SLCO2B1, and SLCO1B3 polymorphisms and susceptibility to bladder cancer risk.

SLCO1B3 SLCO1B1

2.26e-05396224762081
Pubmed

[CYP2D6, CYP3A5, and CYP3A4 gene polymorphism in Russian, Tatar, and Bashkir populations].

CYP2D6 CYP3A4

2.26e-05396225857198
Pubmed

Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.

SLCO1B3 SLCO1B1

2.26e-05396218296417
Pubmed

Impact of genetic variation in CYP2C19, CYP2D6, and CYP3A4 on oxycodone and its metabolites in a large database of clinical urine drug tests.

CYP2D6 CYP3A4

2.26e-05396234480108
Pubmed

Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.

SLCO1B3 SLCO1B1

2.26e-05396230955241
Pubmed

Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations.

SLCO1B3 SLCO1B1

2.26e-05396220660695
Pubmed

Influence of drug formulation on OATP1B-mediated transport of paclitaxel.

SLCO1B3 SLCO1B1

2.26e-05396224755470
Pubmed

Association of Polymorphisms of Cytochrome P450 2D6 With Blood Hydroxychloroquine Levels in Patients With Systemic Lupus Erythematosus.

CYP2D6 CYP3A4

2.26e-05396226316040
Pubmed

Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response.

CYP2D6 CYP3A4

2.26e-05396220350136
Pubmed

OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.

SLCO1B3 SLCO1B1

2.26e-05396229337310
Pubmed

Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.

SLCO1B3 SLCO1B1

2.26e-05396222136368
Pubmed

Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.

SLCO1B3 SLCO1B1

2.26e-05396231967785
Pubmed

Genetic polymorphisms of cytochrome P450 among patients with Balkan endemic nephropathy (BEN).

CYP2D6 CYP3A4

2.26e-05396215708542
Pubmed

Mutation screening in a Norwegian cohort with pheochromocytoma.

NF1 RET

2.26e-05396223407919
Pubmed

Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats.

SLCO1B3 SLCO1B1

2.26e-05396228013215
Pubmed

The role of organic anion-transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics.

SLCO1B3 SLCO1B1

2.26e-05396219890249
Pubmed

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms.

SLCO1B3 SLCO1B1

2.26e-05396220051929
Pubmed

Impact of regulatory polymorphisms in organic anion transporter genes in the human liver.

SLCO1B3 SLCO1B1

2.26e-05396219620935
Pubmed

Urinary metabolites to assess in vivo ontogeny of hepatic drug metabolism in early neonatal life.

CYP2D6 CYP3A4

2.26e-05396217609736
Pubmed

Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1.

SLCO1B3 SLCO1B1

2.26e-05396229422623
Pubmed

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.

SLCO1B3 SLCO1B1

2.26e-05396224825069
Pubmed

Comparison of metabolic soft spot predictions of CYP3A4, CYP2C9 and CYP2D6 substrates using MetaSite and StarDrop.

CYP2D6 CYP3A4

2.26e-05396221605066
Pubmed

Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure.

SLCO1B3 SLCO1B1

2.26e-05396222695893
Pubmed

Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.

CYP2D6 CYP3A4

2.26e-05396212756206
Pubmed

Dispensable role of protein 4.1B/DAL-1 in rodent adrenal medulla regarding generation of pheochromocytoma and plasmalemmal localization of TSLC1.

RET EPB41L3

2.26e-05396219321127
Pubmed

Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.

SLCO1B3 SLCO1B1

2.26e-05396218492796
Pubmed

Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.

SLCO1B3 SLCO1B1

2.26e-05396228389619
Pubmed

Characterization of human cytochrome P450 enzymes catalyzing domperidone N-dealkylation and hydroxylation in vitro.

CYP2D6 CYP3A4

2.26e-05396215327587
Pubmed

Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.

SLCO1B3 SLCO1B1

2.26e-05396226383540
Pubmed

Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.

SLCO1B3 SLCO1B1

2.26e-05396223986199
Pubmed

Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.

SLCO1B3 SLCO1B1

2.26e-05396218413659
Pubmed

Genetic variability of CYP2D6, CYP3A4 and CYP3A5 among the Egyptian population.

CYP2D6 CYP3A4

2.26e-05396233789449
Pubmed

Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.

CYP3A4 SLCO1B1

2.26e-05396225935875
Pubmed

Alteration in placental expression of bile acids transporters OATP1A2, OATP1B1, OATP1B3 in intrahepatic cholestasis of pregnancy.

SLCO1B3 SLCO1B1

2.26e-05396222203093
InteractionENTREP3 interactions

ABCA2 CHRNA9 PCNX3 OR10H2 SCN4A SLC47A1 HERC4 CHRND

3.08e-08120828int:ENTREP3
InteractionHTR3A interactions

ABCA2 SCAP PCNX3 C6orf89 ALG8 SLC47A1 PLPPR3

2.85e-07108827int:HTR3A
InteractionST7L interactions

ABCA2 SCAP OR10H2 CHRND RNF170

5.80e-0740825int:ST7L
InteractionTMEM39A interactions

SCAP CHRNA9 BTNL8 OR10H2 CHRND

1.63e-0649825int:TMEM39A
InteractionSLC12A9 interactions

TPRA1 CHRNA9 OR10H2 NMUR2 CHRND

2.43e-0653825int:SLC12A9
InteractionDNAJC18 interactions

ABCA2 CHRNA9 OR10H2 NMUR2 CHRND

1.36e-0575825int:DNAJC18
InteractionST7 interactions

SCAP CHRNA9 CNOT9 OR10H2 SCN4A A2ML1 UBIAD1 MBOAT2 CHRND

1.63e-05362829int:ST7
InteractionTRPM8 interactions

TRPM4 PCNX3 TRPM8

5.07e-0518823int:TRPM8
InteractionTM2D2 interactions

PCNX3 ALG8 SLC47A1

8.19e-0521823int:TM2D2
InteractionTYW1 interactions

SCAP NMUR2 CHRND ATP6V0A2 RNF170

8.27e-05109825int:TYW1
InteractionFZD2 interactions

SCAP OR10H2 KCNJ10 SCN4A

1.04e-0460824int:FZD2
InteractionPCNX3 interactions

SCAP PCNX3 OR10H2 TRPM8

1.80e-0469824int:PCNX3
InteractionOR10H2 interactions

TRPM4 PCNX3 OR10H2 XPR1

2.12e-0472824int:OR10H2
InteractionTTYH1 interactions

TRPM4 ABCA2 SCAP PCNX3 ALG8 SLC47A1 XPR1

2.21e-04300827int:TTYH1
Cytoband14q11.2

OR6S1 OR4Q2 OR4M1 OR4K5 OR4K14

3.82e-0518095514q11.2
CytobandEnsembl 112 genes in cytogenetic band chr12p12

SLC15A5 SLCO1B3 BCAT1 SLCO1B1

9.32e-05113954chr12p12
Cytoband12q13

MYG1 HSD17B6 SCN8A

4.43e-047195312q13
Cytoband1p13

CD101 CD58

5.65e-04179521p13
CytobandEnsembl 112 genes in cytogenetic band chr14q11

OR6S1 OR4Q2 OR4M1 OR4K5 OR4K14

6.53e-04332955chr14q11
GeneFamilySolute carriers

SLC32A1 SLC25A18 SLC7A13 SLC35D2 SLC16A14 SLC22A10 SLC15A5 SLCO1B3 SLC47A1 SLCO1B1 SLC16A12 SLC5A2 SLC52A3

7.89e-093957513752
GeneFamilyOlfactory receptors, family 4

OR4C3 OR4A8 OR4Q2 OR4A5 OR4M1 OR4K5 OR4K14

1.06e-06129757151
GeneFamilyPhospholipid phosphatase related

PLPPR4 PLPPR3

1.68e-0457521127
GeneFamilyTaste 2 receptors

TAS2R36 TAS2R30 TAS2R46

5.63e-04397531162
GeneFamilySodium voltage-gated channel alpha subunits

SCN4A SCN8A

6.00e-0497521203
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA8

1.50e-0314752805
GeneFamilyCholinergic receptors nicotinic subunits

CHRNA9 CHRND

1.96e-0316752173
GeneFamilyTransient receptor potential cation channels

TRPM4 TRPM8

5.99e-0328752249
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_500

SELENOP CWH43 CYP2D6 SLC7A13 C6orf89 SLC16A14 KCNJ10 SLC47A1 SLC5A2

2.15e-05400819gudmap_kidney_adult_JuxtaGlom_Ren1_500
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 ARHGAP23 SLC35D2 KCNJ10 ATP10B ABCA8

1.25e-071839475472cdce6d99314d229418412acf1fff6340db7d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B SLCO1B1 ABCA8

1.25e-0718394793213124e55d1b673dd345188caf8b5bd31d99fe
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B SLCO1B1 ABCA8

1.29e-07184947f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 ARHGAP23 SLC35D2 KCNJ10 ATP10B ABCA8

1.29e-071849475939527d24d299e562e707469c9123890edd76be
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 ARHGAP23 SLC35D2 KCNJ10 ATP10B ABCA8

1.39e-07186947d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.69e-061859461d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.69e-06185946b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.77e-0618694690eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.77e-06186946bd8a9753df219084e19e7f94447856e86608325c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.86e-06187946f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.86e-06187946b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.95e-0618894614072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

2.95e-06188946b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

3.04e-0618994670eea8c94fa56bb15bee8065de47acea156794e9
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC25A18 SLC35D2 KCNJ10 ATP10B ABCA8

3.04e-06189946784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

3.04e-06189946b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC25A18 SLC35D2 KCNJ10 ATP10B ABCA8

3.13e-0619094607f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC35D2 KCNJ10 ATP10B SLCO1B1 ABCA8

3.13e-061909466b101359f397020a21e2bfd15851cb48e71f4502
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP ABCA2 SLC35D2 KCNJ10 ATP10B ABCA8

3.13e-06190946396b7225c2430db3dc55a3d0db70239b71987229
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELENOP SLC7A13 KCNJ10 EPB41L3 TMEM26

2.27e-051609450544bc465af208da448858d6e174ff56f2e08a46
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNOT9 CD101 CENPI ENOPH1 SLC52A3

2.27e-051609458a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A13 SLC47A1 UBIAD1 KYAT1 PAQR7

3.12e-0517194548fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A13 SLC47A1 UBIAD1 KYAT1 PAQR7

3.12e-0517194505fcc72df50a380a913821b5781d9621df37d328
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNOT9 CD101 CENPI WDFY4 SLC52A3

3.58e-05176945581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP23 SLC35D2 KCNJ10 ATP10B ABCA8

4.43e-05184945a2191dd5546efd357b23e625beb3c5820476f243
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP23 SLC35D2 KCNJ10 ATP10B ABCA8

4.78e-0518794597e520705491c8f52a32025311a9fa7b9176979a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC35D2 KCNJ10 ATP10B ABCA8

4.91e-0518894560242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC35D2 KCNJ10 ATP10B ABCA8

4.91e-05188945d9692b6048d9b85524a07a1807bdd4757731c151
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 SLC35D2 KCNJ10 ATP10B ABCA8

4.91e-05188945505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 SLC35D2 KCNJ10 ATP10B ABCA8

5.03e-0518994537ecbd73408d462b47d7e5611f203143e08a2689
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 SLC35D2 KCNJ10 ATP10B ABCA8

5.16e-051909452de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC35D2 KCNJ10 ATP10B ABCA8

5.16e-05190945ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC47A1 EPB41L3 SDK1 SLC16A12 SLC5A2

5.29e-051919453c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC47A1 EPB41L3 SDK1 SLC16A12 SLC5A2

5.29e-051919451c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC35D2 KCNJ10 ATP10B ABCA8

5.29e-051919452110a1dd10730ad7ee7a265fb1716ab3ddafcf4a
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SELENOP SLC35D2 KCNJ10 ATP10B ABCA8

5.29e-051919452b056cbe2e82e056e1f798974999378460eb1d16
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 SLC35D2 KCNJ10 ATP10B ABCA8

5.29e-05191945a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SELENOP ABCA2 KCNJ10 ATP10B ABCA8

5.42e-051929458dc3016601148243196e925641c9507e9d58c9e0
ToppCellBronchus_Control_(B.)-Immune-TX-TRAM-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CYP2D6 BTNL8 CD101 SLC47A1 WDFY4

5.83e-05195945dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

SLC25A18 SLC35D2 KCNJ10 ATP10B ABCA8

6.58e-05200945e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SELENOP ABCA2 KCNJ10 NIPAL3 ABCA8

6.58e-05200945acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SELENOP ABCA2 KCNJ10 NIPAL3 ABCA8

6.58e-05200945091a18d6efed81cab99955c3047f172170f70476
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SELENOP ABCA2 KCNJ10 NIPAL3 ABCA8

6.58e-052009453b8513defe25262ab4b492345b2628570eaefd17
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 KCNJ10 NMUR2 NIPAL3 ABCA8

6.58e-05200945829978708463a7459fe1041bd90196775bc4b531
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL1R2 PLPPR3 MBOAT2 OR4K14

1.47e-04126944ec32bfd6cd93fbe02f7577893c82b04d209a52e7
DrugProguanil

CYP2D6 CYP3A4 SLC47A1

6.56e-075933ctd:D002727
Drugprobenecid

CYP3A4 SLC16A14 SLCO1B3 SLC47A1 SLCO1B1 SLC16A12 KYAT1

7.29e-07123937CID000004911
Drugipratropium bromide

CYP2D6 CHRNA9 CYP3A4 CHRM5 CHRND

1.22e-0646935CID000003746
Drugnateglinide

CYP3A4 SLCO1B3 SLCO1B1

2.28e-067933ctd:C060142
Drugquindine

CYP2D6 CHRNA9 CYP3A4 HSD17B6 SCN4A SLC47A1 SLCO1B1 CHRND

3.26e-06219938CID000001065
DrugFusidic Acid

CYP3A4 SLCO1B3 SLCO1B1

3.64e-068933ctd:D005672
Drugcimetidine

CYP2D6 CYP3A4 SLC16A14 SLCO1B3 SLC47A1 SLCO1B1 SLC16A12

8.85e-06179937CID000002756
Drugrepaglinide

CYP3A4 SLCO1B3 SLCO1B1

1.06e-0511933ctd:C072379
DrugOndansetron

CYP2D6 CYP3A4 SLC47A1

1.41e-0512933ctd:D017294
Drugglimepiride

CYP3A4 SLCO1B3 SLCO1B1

1.41e-0512933ctd:C057619
Drugnorlevorphanol

CYP2D6 CYP3A4

1.65e-052932ctd:C054116
Drugnorbuprenorphine

CYP2D6 CYP3A4

1.65e-052932ctd:C043585
Drug(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid

SLCO1B3 SLCO1B1

1.65e-052932ctd:C561635
DrugPyrantel

CYP2D6 CYP3A4

1.65e-052932ctd:D011715
Drugdesethylchloroquine

CYP2D6 CYP3A4

1.65e-052932ctd:C007278
DrugYM 758

CYP2D6 CYP3A4

1.65e-052932ctd:C530155
DrugN,O-didesmethylvenlafaxine

CYP2D6 CYP3A4

1.65e-052932ctd:C434333
DrugAC1Q7BBT

CYP3A4 SLCO1B3 SLCO1B1

2.32e-0514933CID000086545
Drugsulfinpyrazone

CYP3A4 SLC16A14 SLCO1B3 SLCO1B1 SLC16A12

2.89e-0587935CID000005342
Drugisoamyl alcohol

MYG1 CYP3A4 BCAT1 KYAT1

4.42e-0548934CID000031260
Drug3-methoxymorphinan

CYP2D6 CYP3A4

4.94e-053932ctd:C028657
DrugN-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine

CYP2D6 CYP3A4

4.94e-053932ctd:C051570
Drugindomethacin phenethylamide

CYP2D6 CYP3A4

4.94e-053932ctd:C489645
DrugVerapamil

CYP2D6 CYP3A4 SLC47A1 RET ABCA8

7.14e-05105935ctd:D014700
Drugorphenadrine

CYP2D6 CYP3A4 SCN4A CHRM5

8.14e-0556934CID000004601
DrugGlyburide

TRPM4 CYP3A4 SLCO1B3 SLCO1B1

9.35e-0558934ctd:D005905
DrugClarithromycin

CYP3A4 SLCO1B3 SLCO1B1

9.60e-0522933ctd:D017291
Drugestradiol-17 beta-glucuronide

SLCO1B3 SLCO1B1 ABCA8

9.60e-0522933ctd:C025483
DrugCI-1034

CYP3A4 SLCO1B3 SLCO1B1

9.60e-0522933CID000157574
DrugQuinine

CYP2D6 CYP3A4 SLC47A1

9.60e-0522933ctd:D011803
Drug1-(6-((2-(dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo(3,4-b)pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea

CYP2D6 CYP3A4

9.85e-054932ctd:C558737
Drugfenproporex

CYP2D6 CYP3A4

9.85e-054932ctd:C026013
Drugoxatomide

CYP2D6 CYP3A4

9.85e-054932ctd:C015408
Drug7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine

CYP2D6 CYP3A4

9.85e-054932ctd:C556297
Drug1-(2-methyl-4-methoxyphenyl)-4-((2-hydroxyethyl)amino)-6-trifluoromethoxy-2,3-dihydropyrrolo(3,2-c)quinoline

CYP2D6 CYP3A4

9.85e-054932ctd:C439392
Drugrabeprazole-thioether

CYP2D6 CYP3A4

9.85e-054932ctd:C523099
DrugDihydromicrocystin Lr

SLCO1B3 SLCO1B1

9.85e-054932CID006441227
Drugrifamycin SV

SLCO1B3 SLCO1B1

9.85e-054932ctd:C023808
Drugmicrocystin-LF

SLCO1B3 SLCO1B1

9.85e-054932ctd:C524165
Drug17-AAG; Up 200; 1uM; HL60; HT_HG-U133A

NF1 SLC35D2 ATP10B MBOAT2 HERC4 SLC5A2

1.06e-041839366166_UP
Drugestrone sulfate

SLCO1B3 SLCO1B1 ABCA8

1.10e-0423933ctd:C017296
Drugprocyclidine

CHRNA9 CHRM5 CHRND

1.25e-0424933CID000004919
Drugbisphenol F

SLCO1B3 SLC47A1 SLCO1B1

1.25e-0424933ctd:C000611646
Drug11-cis-retinal

LRAT ABCA2 CNOT9 CYP3A4 HSD17B6 RET

1.27e-04189936CID000001070
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

NF1 CWH43 CYP3A4 SCN8A ABCA8 SLC5A2

1.27e-041899364430_UP
DrugTramadol

CYP2D6 CYP3A4 SLC47A1

1.42e-0425933ctd:D014147
Druglamotrigine

CYP2D6 CYP3A4 KYAT1

1.42e-0425933ctd:C047781
DrugTiclopidine

CYP2D6 CYP3A4 SLC47A1

1.42e-0425933ctd:D013988
Drugdisopyramide

CHRNA9 CYP3A4 SCN4A CHRND

1.55e-0466934CID000003114
DrugMeglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A

CWH43 SLC35D2 ATP10B SLCO1B1 CHRND SLC5A2

1.59e-041979366445_UP
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; HL60; HT_HG-U133A

RNF14 NF1 BCAT1 RET HERC4 XPO7

1.59e-041979361311_DN
DrugHeliotrine [303-33-3]; Down 200; 12.8uM; HL60; HT_HG-U133A

ABCA2 NF1 IL1R2 BCAT1 PLPPR3 RET

1.59e-041979362180_DN
Drugdimethocaine

CYP2D6 CYP3A4

1.64e-045932ctd:C066888
Drugnatisedine

CYP3A4 SLCO1B1

1.64e-045932CID000064644
DrugL-754,394

CYP2D6 CYP3A4

1.64e-045932CID005481990
Drughyodeoxycholic acid

CYP2D6 CYP3A4

1.64e-045932ctd:C010471
Druglephetamine

CYP2D6 CYP3A4

1.64e-045932ctd:C011896
Drugeupatorin

CYP2D6 CYP3A4

1.64e-045932ctd:C103110
Drug4-ipomeanol

CYP2D6 CYP3A4

1.64e-045932ctd:C001470
Drug2Cmp

CYP2D6 CYP3A4

1.64e-045932CID000023392
Drug2,2',4,4',5,6'-hexabromodiphenyl ether

SLCO1B3 SLCO1B1

1.64e-045932ctd:C555859
DrugN-ethyl-1,2-diphenylethylamine

CYP2D6 CYP3A4

1.64e-045932ctd:C000598690
Drugfenproporex

CYP2D6 CYP3A4

1.64e-045932CID000061810
Drugverapamil

ABCA2 CHRNA9 CYP3A4 KCNJ10 HSD17B6 SCN4A SLCO1B1 ABCA8 CHRND

1.79e-04490939CID000002520
Drugtariquidar

CYP3A4 SLCO1B3 SLCO1B1

1.80e-0427933CID000148201
DrugDigocin

CYP3A4 SLCO1B3 SLCO1B1 ABCA8

1.95e-0470934CID000003062
Drugencainide

CYP2D6 CYP3A4 SCN4A

2.01e-0428933CID000048040
DrugNSC221991

MYG1 SLCO1B1 ABCA8 KYAT1

2.17e-0472934CID000004580
DrugDehydroepiandrosterone Sulfate

CYP3A4 SLCO1B3 SLCO1B1

2.23e-0429933ctd:D019314
Drugfexofenadine

CYP3A4 SLCO1B3 SLC47A1 SLCO1B1

2.29e-0473934CID000003348
DrugNSC100058

CYP2D6 CHRNA9 CYP3A4 CHRND

2.41e-0474934CID000003449
Drugeserine hemisulfate

CHRNA9 CYP3A4 RET CHRND

2.41e-0474934CID000004811
Drugmenatetrenone

CYP3A4 UBIAD1

2.45e-046932ctd:C030814
Drug2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid

CYP3A4 SLCO1B1

2.45e-046932ctd:C054917
Drugtrospium chloride

SLCO1B3 SLCO1B1

2.45e-046932ctd:C003330
DrugN-desmethyltamoxifen

CYP2D6 CYP3A4

2.45e-046932ctd:C028787
Drug8-Methylxanthine

CYP2D6 CYP3A4

2.45e-046932CID000087061
DrugAPETx1, Anthopleura elegantissima

SCN4A SCN8A

2.45e-046932ctd:C475726
Drugprednisolone phosphate

SLCO1B3 SLCO1B1

2.45e-046932CID000004896
Drug5-methoxyindole

CYP2D6 CYP3A4

2.45e-046932ctd:C487413
DrugCyclodextrins

CYP2D6 CYP3A4

2.45e-046932ctd:D003505
Drugmepirodipine

CYP2D6 CYP3A4

2.45e-046932ctd:C050699
DrugS-(chloro-1,2,2-trifluoroethyl)-L-cysteine

BCAT1 KYAT1

2.45e-046932CID000107692
Drugmilnacipran

CYP2D6 CYP3A4 ATP6V0A2

2.47e-0430933CID000055480
Drugdiphenhydramine

CYP2D6 CYP3A4 SCN4A CHRM5

2.54e-0475934CID000003100
Drugtropicamide

CHRNA9 CHRM5 CHRND

3.00e-0432933CID000005593
Drugamiloride

SLC32A1 TRPM4 CHRNA9 SCN4A SLC47A1 SLC16A12 CHRND

3.11e-04315937CID000016230
Drugdecamethrin

CYP2D6 CYP3A4 SCN8A BCAT1 RET

3.34e-04146935ctd:C017180
Drugbupropion

CYP2D6 CHRNA9 CYP3A4 SCN4A

3.41e-0481934CID000000444
Drug5-n-butyl-pyrazolo(1,5-a)pyrimidine

CYP2D6 CYP3A4

3.42e-047932ctd:C547858
Drugretinyl stearate

LRAT XPR1

3.42e-047932CID006438398
DrugDextrorphan

CYP2D6 CYP3A4

3.42e-047932ctd:D003917
Drug16-O-demethylaconitine

CYP2D6 CYP3A4

3.42e-047932ctd:C486136
Drugdemethylphalloin

SLCO1B3 SLCO1B1

3.42e-047932CID000114793
Drugtelithromycin

CYP2D6 CYP3A4

3.42e-047932ctd:C106791
Drug5-hydroxydiclofenac

CYP2D6 CYP3A4

3.42e-047932ctd:C117715
Drugnorfluoxetine

CYP2D6 CYP3A4

3.42e-047932ctd:C036139
Drugquinidine-N-oxide

CYP2D6 CYP3A4

3.42e-047932CID000050979
Drug12-hydroxyellipticine

CYP2D6 CYP3A4

3.42e-047932ctd:C517214
DrugE-10

CYP2D6 CYP3A4 RET

3.60e-0434933CID006452259
DiseaseRotor syndrome

SLCO1B3 SLCO1B1

9.00e-062892cv:C0220991
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC

SLCO1B3 SLCO1B1

9.00e-062892C4016905
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE

SLCO1B3 SLCO1B1

9.00e-062892237450
DiseaseRotor Syndrome

SLCO1B3 SLCO1B1

9.00e-062892C0220991
DiseaseOndansetron response

CYP2D6 CYP3A4

2.69e-053892cv:CN417142
Diseaseestrone conjugate measurement

CYP3A4 SLCO1B1

5.38e-054892EFO_0007971
DiseaseClozapine response

CYP2D6 CYP3A4

5.38e-054892cv:CN077971
Diseasebilirubin metabolic disorder (implicated_via_orthology)

SLCO1B3 SLCO1B1

8.94e-055892DOID:2741 (implicated_via_orthology)
Diseasebilirubin metabolic disorder (is_implicated_in)

SLCO1B3 SLCO1B1

1.34e-046892DOID:2741 (is_implicated_in)
Diseasedeoxycholic acid glucuronide measurement

SLCO1B3 SLCO1B1

2.49e-048892EFO_0800575
DiseaseTremor, Neonatal

CYP2D6 SCN8A

3.19e-049892C0235843
DiseaseAction Tremor

CYP2D6 SCN8A

3.19e-049892C0234376
DiseasePassive Tremor

CYP2D6 SCN8A

3.19e-049892C0234377
DiseaseStatic Tremor

CYP2D6 SCN8A

3.19e-049892C0234378
DiseaseResting Tremor

CYP2D6 SCN8A

3.19e-049892C0234379
DiseaseIntermittent Tremor

CYP2D6 SCN8A

3.19e-049892C0234372
DiseaseFine Tremor

CYP2D6 SCN8A

3.19e-049892C0234373
DiseaseCoarse Tremor

CYP2D6 SCN8A

3.19e-049892C0234374
DiseaseMassive Tremor

CYP2D6 SCN8A

3.19e-049892C0234375
DiseasePersistent Tremor

CYP2D6 SCN8A

3.19e-049892C0234370
DiseaseContinuous Tremor

CYP2D6 SCN8A

3.19e-049892C0234371
DiseaseDarkness Tremor

CYP2D6 SCN8A

3.19e-049892C0234381
DiseaseInvoluntary Quiver

CYP2D6 SCN8A

3.19e-049892C1527384
DiseaseTremor, Perioral

CYP2D6 SCN8A

3.19e-049892C0235078
DiseaseNerve Tremors

CYP2D6 SCN8A

3.19e-049892C0235083
DiseaseTremor, Limb

CYP2D6 SCN8A

3.19e-049892C0235081
DiseaseTremor, Muscle

CYP2D6 SCN8A

3.19e-049892C0235082
DiseaseSenile Tremor

CYP2D6 SCN8A

3.19e-049892C0149840
DiseaseSaturnine Tremor

CYP2D6 SCN8A

3.19e-049892C0040827
DiseasePill Rolling Tremor

CYP2D6 SCN8A

3.19e-049892C0751564
DiseaseTremor, Semirhythmic

CYP2D6 SCN8A

3.19e-049892C0751565
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B3 SLCO1B1

3.19e-049892EFO_0800562
DiseaseX-21467 measurement

SLCO1B3 SLCO1B1

3.19e-049892EFO_0020007
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN4A SCN8A

3.98e-0410892DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN4A SCN8A

3.98e-0410892DOID:0080422 (implicated_via_orthology)
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

CYP3A4 SLCO1B1

3.98e-0410892EFO_0022090
Diseasesleep disorder (implicated_via_orthology)

NF1 NPSR1

4.86e-0411892DOID:535 (implicated_via_orthology)
DiseaseTremor

CYP2D6 SCN8A

4.86e-0411892C0040822
Diseaseandrostenediol (3beta,17beta) monosulfate (2) measurement

CYP3A4 SLCO1B1

4.86e-0411892EFO_0800295
DiseaseLenticulostriate Disorders

CYP2D6 XPR1

5.82e-0412892C0750951
DiseaseExtrapyramidal Disorders

CYP2D6 XPR1

5.82e-0412892C0015371
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN4A SCN8A

5.82e-0412892DOID:0060170 (implicated_via_orthology)
DiseaseBasal Ganglia Diseases

CYP2D6 XPR1

5.82e-0412892C0004782
Diseaseecosanoids measurement

SLC22A10 SLCO1B3 SLCO1B1

6.21e-0455893EFO_0020044
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B3 SLCO1B1

6.87e-0413892EFO_0800474
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

CYP3A4 SLCO1B1

6.87e-0413892EFO_0800293
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

CYP3A4 SLCO1B1

6.87e-0413892EFO_0800284
DiseaseX-21470 measurement

CYP3A4 SLCO1B1

8.00e-0414892EFO_0800817
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

SCN4A CHRND

1.05e-0316892C0751885
DiseaseDrug-induced agranulocytosis

SCN8A TMEM26

1.05e-0316892HP_0012235
DiseasePheochromocytoma, Extra-Adrenal

NF1 RET

1.05e-0316892C1257877
Diseaseobstructive sleep apnea

LINC01619 HSD17B6 SLC52A3

1.06e-0366893EFO_0003918
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

SCN4A CHRND

1.19e-0317892C0751883
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

CYP3A4 SLCO1B1

1.33e-0318892EFO_0800288
DiseaseCongenital Myasthenic Syndromes, Presynaptic

SCN4A CHRND

1.49e-0319892C0751884
Diseasemetabolonic lactone sulfate measurement

CYP3A4 SLCO1B1

1.49e-0319892EFO_0800659
DiseasePheochromocytoma

NF1 RET

1.49e-0319892C0031511
Diseasesphingomyelin measurement

GALR1 C6orf89 SCN8A SLCO1B1 SDK1

1.56e-03278895EFO_0010118
Diseasecerebellum white matter volume change measurement, age at assessment

EPB41L3 ABCA8

1.65e-0320892EFO_0008007, EFO_0021498
DiseaseNephritis, Tubulointerstitial

CYP2D6 SLC16A12

1.82e-0321892C0041349
Disease5alpha-androstan-3beta,17beta-diol disulfate measurement

CYP3A4 SLCO1B1

2.00e-0322892EFO_0021115
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

NF1 RET

2.18e-0323892C1708353
DiseaseNephritis, Interstitial

CYP2D6 SLC16A12

2.38e-0324892C0027707
DiseaseMyasthenic Syndromes, Congenital

SCN4A CHRND

2.38e-0324892C0751882
Diseasepartial thromboplastin time

LRAT SELENOP

2.38e-0324892EFO_0004310
DiseaseNoonan Syndrome

NF1 A2ML1

2.38e-0324892C0028326

Protein segments in the cluster

PeptideGeneStartEntry
TISFVSYILSLFPSP

nan

11

Q9Y3F1
PALALYVFTIATEPL

APH1B

16

Q8WW43
IFRSSCPISVTYFPF

CHRND

146

Q07001
ALLFVLLSPVGPYFS

BCAT1

181

P54687
FGLIPSPSVYLVASF

CATSPERE

896

Q5SY80
HLYFTLNPRFISVFP

BTNL8

386

Q6UX41
AFKPFFVDLTLPYSV

A2ML1

786

A8K2U0
IFSQADPSPLLFYLC

ARHGEF11

331

O15085
PLFLYPFLHTVSKTR

CNOT9

116

Q92600
ILLYSFSVPESLFPG

C1orf74

216

Q96LT6
LPRFISLYIFSFLSP

ECT2L

81

Q008S8
IPCVLISFLAPLSFY

CHRNA9

246

Q9UGM1
ISFLAPLSFYLPAAS

CHRNA9

251

Q9UGM1
PTFYLVCFLTPVVAL

ATP10B

1296

O94823
VCFLTPVVALLPRYF

ATP10B

1301

O94823
LAALYTIVAVFPSPL

R3HDM2

926

Q9Y2K5
ATTYAVLTPFLSPII

OR10H2

276

O60403
YTVITPFLSPIIFSL

OR10X1

291

Q8NGY0
PLFIIVLASFTYLSF

PAQR7

106

Q86WK9
FASYAFAPLSLIVPL

NIPAL3

91

Q6P499
FFLYVLESLPSPTLT

CD58

116

P19256
SPFLILPLTFYHVVD

KCNJ10

246

P78508
RSHFFLPVSVVYVPI

NMUR2

41

Q9GZQ4
VPFVLLSIKPSLTFY

MBOAT2

431

Q6ZWT7
NPLIYCVFSSSISFP

NPSR1

326

Q6W5P4
SGLSPPVAIFFVIYT

MYG1

281

Q9HB07
LDPFFLSITVFPFLI

CYP3A4

216

P08684
FPPVSLYGLTLFSAS

PCNX3

881

Q9H6A9
LDVFLSAFYTVVPPT

OR14L1P

271

Q8NHC6
HILFSSIYLLVPPFL

OR52A1

276

Q9UKL2
PFTISPLDKFLAIFY

OR4K5

261

Q8NGD3
PLDKFLAIFYTVFTP

OR4K5

266

Q8NGD3
LLSVFYTIFTPLLNP

OR4K14

271

Q8NGD5
FHTVIFPLLNPIIYT

OR4M1

276

Q8NGD0
PCIFIYARPFSTFSV

OR4Q2

251

P0C623
LADIPVTICTYPFVF

HERC4

651

Q5GLZ8
LVSYTTLPAIFIPFF

LRAT

211

O95237
LVAPVPHSFYSFELI

KBTBD7

466

Q8WVZ9
TTFVTPLLNPFIYAL

OR6S1

281

Q8NH40
LFCIPFQATVYALPT

GALR1

86

P47211
TTPIAFVKDILFPYI

ENOPH1

21

Q9UHY7
PSRICSSAPLLYFLF

CD101

946

Q93033
SSAPLLYFLFICPFV

CD101

951

Q93033
DAKFFFIPLSYLPTS

HSD17B6

286

O14756
YTDTFLPFIHTICPL

BFAR

291

Q9NZS9
TFPSTRLPLTLVYCF

SDR42E1

276

Q8WUS8
LRDIPFSIIYFPLFA

SLC25A18

191

Q9H1K4
FAFLVSPSPYELCAV

CYP2D6

481

P10635
IILFVFDLPAYTSPT

ABCA2

1856

Q9BZC7
YTSPTNFPAVLSLFL

ABCA2

1866

Q9BZC7
LYKFFAPALISVSLP

CENPI

241

Q92674
ILLTAYFVIQPFSPL

C6orf89

71

Q6UWU4
ATAFLFIIEPPYFTA

SDK1

376

Q7Z5N4
ILAPFLEYFSTCLFP

SLC15A5

361

A6NIM6
LCASYPIPIILFTGF

SCAP

21

Q12770
ASFSVPYALTLSFPL

EPB41L3

646

Q9Y2J2
LFFVPCIFIYVRPVS

OR4A5

246

Q8NH83
SIIASPFLGSPVYFF

OR4A8

46

P0C604
PTLASPVYFFLANLS

OR4C3

51

Q8NH37
ALFFVPCIFTYVHPF

OR4C3

246

Q8NH37
SIAFLSPIFLTITPF

CWH43

46

Q9H720
AIIFSYPSTHPFILI

TAS2R30

266

P59541
AIIFSYPSTHPFILI

TAS2R36

266

P0DTE0
AIAFSYPSTHPFILI

TAS2R46

266

P59540
KALLTTYGFPSPIFL

SLC35D2

46

Q76EJ3
SRYLPAHFSPLVFFL

SLC52A3

211

Q9NQ40
SPAIFLYLISIVPSL

TMEM26

66

Q6ZUK4
SATPALYLLSPFSVV

SCN4A

106

P35499
AYSSFVIPFIHLPEI

SLC16A14

326

Q7RTX9
QSLPLLVPFSCTFGY

SLC16A12

371

Q6ZSM3
AFAPTFPVYCVLRFL

SLC22A10

191

Q63ZE4
TFGYPPLTKILASFF

KYAT1

66

Q16773
FYLISPLDFVPEALF

RNF170

211

Q96K19
LLASVPPVFGLYTSF

SLC26A10

46

Q8NG04
AFLPFISYPQILTLS

IL1R2

131

P27930
HLGLPFSFLTFPYVE

SELENOP

146

P49908
GLFSIISSIPFFFLP

SLCO1B1

266

Q9Y6L6
TYVTIFIPALPATFL

SLC47A1

156

Q96FL8
IFPDAYTLTFIPVIS

SLFNL1

296

Q499Z3
IFESDIPFIFTFLIP

ABCA8

1156

O94911
PTITFGTAIAAFYIP

CHRM5

191

P08912
TTGHYSLFPLLFTAP

ALG8

411

Q9BVK2
FVISFFPSLIYPLQV

LINC01619

81

G3V211
LLACFFAPISVIPTY

XPR1

331

Q9UBH6
LLPCFYFVELPILAS

PLPPR4

66

Q7Z2D5
SGFEYTICFLPPLVL

RNF14

61

Q9UBS8
FFLVYSLVVILPKTP

TPRA1

201

Q86W33
YPALIPITTASFIAA

TMEM128

116

Q5BJH2
SYLAPPVSAVFVLAL

SLC5A2

461

P31639
TLLPCFYFVELPIVA

PLPPR3

16

Q6T4P5
FTLRHFIVYPPESAV

ARHGAP23

56

Q9P227
GLFSIISSIPFFFLP

SLCO1B3

266

Q9NPD5
LTPEFFYLPEFLTNC

WDFY4

2691

Q6ZS81
PYLFHVVTFLVATGP

NF1

2101

P21359
FSATPALYILSPFNL

SCN8A

106

Q9UQD0
PYKVFLSFPLATIVI

SLC7A13

391

Q8TCU3
AIFPLVYAIPLALST

UBIAD1

211

Q9Y5Z9
FPLLTVYLKVFLSPT

RET

116

P07949
TLQLFFDLYHSIPPS

XPO7

261

Q9UIA9
LLSYPLPFFAAVEVL

SLC32A1

391

Q9H598
LAPVFALFVPFYCSI

UBAC2

131

Q8NBM4
PPELVLYSLVFVLFC

TRPM8

766

Q7Z2W7
AFFCPPLIYTRLITF

TRPM4

696

Q8TD43
PALFTIITFPFLFAV

ATP6V0A2

396

Q9Y487
LALVPTPALFYLFTA

JKAMP

281

Q9P055
TPALFYLFTAKFTEP

JKAMP

286

Q9P055