Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

LDHAL6A RDH10 L2HGDH LDHD HSD3B7 FASN HSD17B11

9.48e-061381077GO:0016614
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

LDHAL6A RDH10 LDHD HSD3B7 FASN HSD17B11

6.29e-051271076GO:0016616
DomainNHL_repeat_subgr

TRIM2 TRIM3 TRIM32

1.54e-0591083IPR013017
DomainIG_FLMN

FLNA TRIM2 TRIM3

2.19e-05101083SM00557
DomainNHL

TRIM2 TRIM3 TRIM32

2.19e-05101083PF01436
DomainNHL_repeat

TRIM2 TRIM3 TRIM32

2.19e-05101083IPR001258
DomainFilamin

FLNA TRIM2 TRIM3

3.00e-05111083PF00630
DomainFILAMIN_REPEAT

FLNA TRIM2 TRIM3

3.00e-05111083PS50194
DomainFilamin/ABP280_rpt

FLNA TRIM2 TRIM3

3.00e-05111083IPR001298
DomainFilamin/ABP280_repeat-like

FLNA TRIM2 TRIM3

3.00e-05111083IPR017868
DomainIFI44_fam

IFI44 IFI44L

3.31e-0521082IPR024644
DomainDUF1088

NBEA LRBA

3.31e-0521082IPR010508
DomainDUF1088

NBEA LRBA

3.31e-0521082PF06469
DomainNHL

TRIM2 TRIM3 TRIM32

5.16e-05131083PS51125
DomainFG_GAP

ITFG2 ITGA2B ITGA4

2.67e-04221083PS51470
DomainDUF4704

NBEA LRBA

3.28e-0451082IPR031570
DomainDUF4704

NBEA LRBA

3.28e-0451082PF15787
DomainFG-GAP

ITFG2 ITGA2B ITGA4

3.48e-04241083PF01839
DomainFG-GAP

ITFG2 ITGA2B ITGA4

3.48e-04241083IPR013517
DomainPH_BEACH

NBEA LRBA

4.89e-0461082PF14844
DomainSUN

SUN1 SUCO

4.89e-0461082PS51469
DomainSUN_dom

SUN1 SUCO

6.83e-0471082IPR012919
DomainSad1_UNC

SUN1 SUCO

6.83e-0471082PF07738
DomainPH-BEACH_dom

NBEA LRBA

9.07e-0481082IPR023362
Domain-

NBEA LRBA

9.07e-04810822.30.29.40
DomainPH_BEACH

NBEA LRBA

9.07e-0481082PS51783
DomainZnf-RING_LisH

TRIM2 TRIM3 TRIM32

9.88e-04341083IPR027370
Domainzf-RING_UBOX

TRIM2 TRIM3 TRIM32

9.88e-04341083PF13445
DomainBEACH_dom

NBEA LRBA

1.16e-0391082IPR000409
DomainBEACH

NBEA LRBA

1.16e-0391082PS50197
DomainBeach

NBEA LRBA

1.16e-0391082PF02138
Domain-

NBEA LRBA

1.16e-03910821.10.1540.10
DomainBeach

NBEA LRBA

1.16e-0391082SM01026
DomainMIP_CS

AQP1 MIP

1.45e-03101082IPR022357
Domain-

TRIM2 TRIM3 TRIM32

1.48e-033910832.120.10.30
DomainIntegrin_alpha

ITGA2B ITGA4

1.76e-03111082PF00357
Domain6-blade_b-propeller_TolB-like

TRIM2 TRIM3 TRIM32

2.38e-03461083IPR011042
DomainMIP

AQP1 MIP

2.88e-03141082PS00221
DomainMIP

AQP1 MIP

2.88e-03141082PF00230
Domain-

LDHAL6A RDH10 HSD3B7 FASN HSD17B11

3.01e-0316910853.40.50.720
DomainIg_E-set

FLNA TRIM2 PKHD1L1 TRIM3

3.12e-031041084IPR014756
DomainBbox_C

TRIM2 TRIM3

3.31e-03151082IPR003649
Domain-

JARID2 ARID2

3.31e-031510821.10.150.60
DomainMIP

AQP1 MIP

3.31e-03151082IPR000425
DomainBBC

TRIM2 TRIM3

3.31e-03151082SM00502
DomainBRIGHT

JARID2 ARID2

3.31e-03151082SM00501
DomainARID_dom

JARID2 ARID2

3.31e-03151082IPR001606
DomainARID

JARID2 ARID2

3.31e-03151082PS51011
Domain-

AQP1 MIP

3.31e-031510821.20.1080.10
DomainARID

JARID2 ARID2

3.31e-03151082PF01388
DomainAquaporin-like

AQP1 MIP

3.31e-03151082IPR023271
DomainNAD(P)-bd_dom

LDHAL6A RDH10 HSD3B7 FASN HSD17B11

3.33e-031731085IPR016040
DomainIntegrin_alpha_C_CS

ITGA2B ITGA4

3.77e-03161082IPR018184
Domainadh_short

RDH10 FASN HSD17B11

3.97e-03551083PF00106
DomainIntegrin_alpha-2

ITGA2B ITGA4

4.77e-03181082IPR013649
DomainIntegrin_alpha2

ITGA2B ITGA4

4.77e-03181082PF08441
DomainIntegrin_alpha

ITGA2B ITGA4

4.77e-03181082IPR000413
DomainINTEGRIN_ALPHA

ITGA2B ITGA4

4.77e-03181082PS00242
DomainARM-like

DNAJC13 NBEA ARID2 ANKAR LRBA GCN1

4.84e-032701086IPR011989
DomainInt_alpha_beta-p

ITGA2B ITGA4

5.31e-03191082IPR013519
DomainInt_alpha

ITGA2B ITGA4

5.31e-03191082SM00191
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TRERF1 FLNA DNAJC13 TTC28 GTF3C4 FASN RESF1 ZFHX4 LRBA GCN1 VCPIP1

1.07e-074181111134709266
Pubmed

TRIM-NHL proteins in development and disease.

TRIM2 TRIM3 TRIM32

1.26e-074111326514622
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

FLNA LDHAL6A ESYT1 OBSCN PSMD9 FLG2 MSR1 ANKAR PALM CC2D2A FH GCN1

2.71e-075641111221565611
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

FLNA TTC28 PPP1R12A SMCHD1 GTF3C4 FASN ARID2 NFRKB LRBA GCN1 VCPIP1

1.57e-065491111138280479
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DPP7 FLNA PPP1R12A PSMD9 BCAR1 CMYA5 GTF3C4 FASN PTPN12 EIF2S3 PAFAH1B3 NFRKB LRBA FH OGA GCN1 VCPIP1

3.70e-0614551111722863883
Pubmed

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.

FLNA L2HGDH EIF2S3B PPIG PDP1 EIF2S3 FH

4.23e-06203111735012549
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

FLNA LDHAL6A MLEC SPTLC2 ESYT1 L2HGDH SRR FASN PAFAH1B3 LRBA FH GCN1 PGM2

4.77e-068781111337223481
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FLNA ESYT1 PPP1R12A SMCHD1 GTF3C4 FASN PTPN12 EIF2S3 ARID2 LRBA OGA GCN1 VCPIP1

9.24e-069341111333916271
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FLNA KLF12 AEN FOXK2 PPP1R12A SUN1 OBSCN ZNF600 RESF1 CANT1 AGA NFRKB SUCO RAB11FIP3

9.52e-0610841111411544199
Pubmed

Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus.

IFI44 IFI44L

1.01e-052111232611756
Pubmed

β-Actin and fascin-2 cooperate to maintain stereocilia length.

CDH23 FSCN2

1.01e-052111223658152
Pubmed

Aquaporin 0 plays a pivotal role in refractive index gradient development in mammalian eye lens to prevent spherical aberration.

AQP1 MIP

1.01e-052111225229686
Pubmed

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

BCAR1 PTPN12

1.01e-05211128887669
Pubmed

Otoprotective effects of mouse nerve growth factor in DBA/2J mice with early-onset progressive hearing loss.

CDH23 FSCN2

1.01e-052111228345280
Pubmed

Unique and analogous functions of aquaporin 0 for fiber cell architecture and ocular lens transparency.

AQP1 MIP

1.01e-052111221511033
Pubmed

Integrin trafficking regulates adhesion to fibronectin during differentiation of mouse peri-implantation blastocysts.

ITGA2B ITGA4

1.01e-05211129291578
Pubmed

Nitric oxide-induced inhibition of aortic smooth muscle cell motility: role of PTP-PEST and adaptor proteins p130cas and Crk.

BCAR1 PTPN12

1.01e-052111212714323
Pubmed

Sexually dimorphic expression of the X-linked gene Eif2s3x mRNA but not protein in mouse brain.

EIF2S3B EIF2S3

1.01e-052111216325480
Pubmed

A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice.

CDH23 FSCN2

1.01e-052111218662770
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNA FOXK2 MLEC SPTLC2 ESYT1 SMCHD1 EIF2S3B SBSN FASN PTPN12 TRIM32 GCN1 VCPIP1

1.44e-059741111328675297
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

OBSCN NBEA EPG5 RESF1 ARID2

1.88e-05101111510997877
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ARHGAP32 TTC28 ESYT1 ZDHHC8 LRBA GCN1 VCPIP1

2.27e-05263111734702444
Pubmed

ACSL4 upregulates IFI44 and IFI44L expression and promotes the proliferation and invasiveness of head and neck squamous cell carcinoma cells.

IFI44 IFI44L

3.02e-053111238989827
Pubmed

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.

ESYT1 VPS13A

3.02e-053111230093493
Pubmed

The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.

NBEA LRBA

3.02e-053111228814779
Pubmed

Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria.

FH MMUT

3.02e-053111231648943
Pubmed

Novel RPTPγ and RPTPζ splice variants from mixed neuron-astrocyte hippocampal cultures as well as from the hippocampi of newborn and adult mice.

AQP1 PTPRZ1

3.02e-053111238952869
Pubmed

Structural mechanism of integrin inactivation by filamin.

FLNA ITGA2B

3.02e-053111225849143
Pubmed

Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic.

MSR1 SIGLEC1

3.02e-053111227601677
Pubmed

Gain-of-Function Mutation in Filamin A Potentiates Platelet Integrin αIIbβ3 Activation.

FLNA ITGA2B

3.02e-053111228428218
Pubmed

Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity.

FLNA ITGA2B

3.02e-053111230602618
Pubmed

Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST.

BCAR1 PTPN12

3.02e-05311129920935
Pubmed

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition.

BCAR1 PTPN12

3.02e-05311129285683
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

MGAT4B OBSCN PSMD9 BCAR1 TUBGCP6 ADAMTS10 PTPN12 ARID2 VPS13A CHCHD2 PALM NDUFAF6 SLC5A12 MSS51

3.35e-0512151111415146197
Pubmed

IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.

ITGA2B ITGA4 SLC17A7

3.47e-0520111322687584
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

DNAJC13 TTC28 ESYT1 NBEA FLG2 PKHD1L1 ZBED6 EIF2S3 VPS13A LRBA GCN1

4.03e-057771111135844135
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA MGAT4B FOXK2 ESYT1 RDH10 OBSCN ZDHHC8 FASN CANT1 PALM LRBA GCN1 RAB11FIP3

5.29e-0511051111335748872
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

FLNA SMCHD1 L2HGDH FASN EIF2S3 FH OGA GCN1 MMUT

5.60e-05534111935032548
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNA MLEC ESYT1 GTF3C4 EPG5 FASN EIF2S3 LRBA FH GCN1 PGM2

5.65e-058071111130575818
Pubmed

CD169+ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling.

SIGLEC1 LTBR

6.03e-054111235031565
Pubmed

Aquaporin 0 Modulates Lens Gap Junctions in the Presence of Lens-Specific Beaded Filament Proteins.

AQP1 MIP

6.03e-054111229196765
Pubmed

Lens opacity: a new gene for congenital cataract on chromosome 10 of the mouse.

CDH23 MIP

6.03e-05411127333462
Pubmed

Nephrocystin-1 interacts directly with Ack1 and is expressed in human collecting duct.

ARHGAP32 BCAR1

6.03e-054111218477472
Pubmed

Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB.

EIF2S3B EIF2S3

6.03e-054111231836389
Pubmed

Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model.

BCAR1 PTPN12

6.03e-05411129748319
Pubmed

Lens aquaporins function as peroxiporins to facilitate membrane transport of hydrogen peroxide.

AQP1 MIP

6.03e-054111232063362
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLNA DNAJC13 MLEC ESYT1 PPP1R12A SMCHD1 L2HGDH PSMD9 ERGIC2 FASN PTPN12 TRIM32 EIF2S3 PGM2

6.77e-0512971111433545068
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DNAJC13 FOXK2 MLEC ESYT1 PPP1R12A RDH10 CDH23 PSMD9 GTF3C4 TRIM32 CRNN CHCHD2 BBS12 GCN1

8.22e-0513211111427173435
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

FLNA ARHGAP32 ESYT1 SBSN FASN CANT1 EIF2S3 GCN1 VCPIP1

8.61e-05565111925468996
Pubmed

Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.

NBEA SLC17A7 LRBA

8.75e-0527111319723784
Pubmed

Functional interactions between ubiquitin E2 enzymes and TRIM proteins.

TRIM2 TRIM3 TRIM32

8.75e-0527111321143188
Pubmed

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.

RDH10 HSD3B7 FASN HSD17B11

9.03e-0573111419027726
Pubmed

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.

KLF12 TTC28 BCAR1 LDHD

9.03e-0573111425086665
Pubmed

Functional expression of aquaporins in embryonic, postnatal, and adult mouse lenses.

AQP1 MIP

1.00e-045111217377981
Pubmed

BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function.

NBEA LRBA

1.00e-045111212160729
Pubmed

Aquaporin expression in developing human teeth and selected orofacial tissues.

AQP1 MIP

1.00e-045111212522663
Pubmed

Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.

BCAR1 PTPN12

1.00e-045111228808245
Pubmed

Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development.

BCAR1 PTPN12

1.00e-045111217070019
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

FLNA DNAJC13 MLEC ESYT1 SUN1 ERGIC2 GTF3C4 SBSN ZNF16 FASN PAFAH1B3 ZNF468 HSD17B11

1.24e-0412031111329180619
Pubmed

Multiple genes encoding zinc finger domains are expressed in human T cells.

ZNF16 ZNF20 ZNF45

1.33e-043111132288909
Pubmed

Interaction network of human early embryonic transcription factors.

TRERF1 FOXK2 FLG2 RESF1 ZFHX4 ARID2 NFRKB

1.39e-04351111738297188
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

DNAJC13 TTC28 SPTLC2 L2HGDH SRR PSMD9 GTF3C4 TUBGCP6 VPS13A

1.46e-04606111936538041
Pubmed

Integrins take partners: cross-talk between integrins and other membrane receptors.

ITGA2B ITGA4

1.50e-04611129789327
Pubmed

An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan.

NBEA LRBA

1.50e-046111219482073
Pubmed

Two separate mechanisms of enforced viral replication balance innate and adaptive immune activation.

SIGLEC1 LTBR

1.50e-046111226553386
Pubmed

Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins.

ITGA2B ITGA4

1.50e-046111214681217
Pubmed

1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.

SPTLC2 ITGA2B

1.50e-046111234762852
Pubmed

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses.

FLNA ITGA4

1.50e-046111210604475
Pubmed

Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses.

HSD3B7 SIGLEC1

1.50e-046111222999953
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

DPP7 SMCHD1 SUN1 ITGA2B FLG2 FASN AGA HSD17B11 GCN1

1.59e-04613111922268729
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

FLNA ESYT1 FASN EIF2S3 GCN1 VCPIP1

1.78e-04256111633397691
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DNAJC13 NBEA GCN1 RAB11FIP3

1.78e-0487111412465718
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

MLEC SPTLC2 ESYT1 L2HGDH EIF2S3B PSMD9 GTF3C4 FASN TRIM32 EIF2S3 HSD17B11 OGA GCN1

1.91e-0412571111337317656
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TRERF1 FLNA DNAJC13 GTF3C4 TUBGCP6 PPIG FASN NFRKB OGA VCPIP1

1.92e-047741111015302935
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

PPP1R12A OBSCN L2HGDH NBEA GTF3C4 AGA ARID2 LRBA

2.01e-04497111836774506
Pubmed

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts.

BCAR1 PTPN12

2.10e-047111210085298
Pubmed

Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.

BCAR1 LDHD

2.10e-047111223665963
Pubmed

Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development.

EIF2S3B EIF2S3

2.10e-047111215669143
Pubmed

The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand.

ITGA2B ITGA4

2.10e-047111237184585
Pubmed

A proteome-scale map of the SARS-CoV-2-human contactome.

TRIM2 KLHL28 RGP1 TRIM3 TRIM32

2.41e-04173111536217029
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

FLNA FLG2 GTF3C4 SBSN FASN GCN1

2.47e-04272111631010829
Pubmed

Evolutionarily conserved regulators of tau identify targets for new therapies.

SPTLC2 ESYT1 RDH10 FLG2 FASN TRIM32 LRBA HSD17B11

2.58e-04516111836610398
Pubmed

MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.

FLNA FASN

2.79e-048111234131310
Pubmed

MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.

TRIM3 TRIM32 ASB11

2.87e-0440111330759391
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TRERF1 L2HGDH GTF3C4 JARID2 PTPN12 RESF1 GCN1

2.90e-04396111726687479
Pubmed

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

FLNA ESYT1 FLG2 FASN EIF2S3 FH GCN1

2.94e-04397111721319273
Pubmed

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.

MLEC ESYT1 RGP1 SBSN TRIM32 GCN1

2.99e-04282111635007762
Pubmed

The tripartite motif family identifies cell compartments.

TRIM2 TRIM3 TRIM32

3.09e-0441111311331580
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

FLNA KLF12 AEN ITFG2 SPTLC2 HSD3B7 FASN ARID2 NFRKB NDUFAF6 OGA GCN1 RAB11FIP3

3.21e-0413271111332694731
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

DNAJC13 SMCHD1 OGA RAB11FIP3

3.28e-0410211149734811
Pubmed

Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution.

EIF2S3B EIF2S3

3.58e-04911129736774
Pubmed

Wnt pathway anomalies in developing amygdalae of Turner syndrome-like mice.

EIF2S3B EIF2S3

3.58e-049111217873295
Pubmed

Defining the membrane proteome of NK cells.

FLNA DNAJC13 MLEC ESYT1 ERGIC2 ITGA4 TUBGCP6 FASN PAFAH1B3 LRBA OGA GCN1

3.61e-0411681111219946888
Pubmed

Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia.

AQP1 MIP

4.47e-0410111210318966
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

FLNA ESYT1 SMCHD1 ITGA4 FASN EIF2S3 PAFAH1B3 LRBA GCN1

4.51e-04707111919738201
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ARHGAP32 MLEC TTC28 ESYT1 FASN EIF2S3 LRBA GCN1 VCPIP1

4.56e-04708111939231216
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PPP1R12A PTPN12 PTPRZ1

4.63e-0447111319167335
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FLNA ESYT1 SUN1 FASN VPS13A LRBA GCN1 VCPIP1

4.88e-04568111837774976
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

FLNA DNAJC13 SMCHD1 FASN GCN1

4.90e-04202111533005030
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

FLNA L2HGDH SRR PSMD9 GTF3C4 FASN EIF2S3 HSD17B11 GCN1

5.40e-04725111927025967
InteractionRCOR1 interactions

FLNA KLF12 DNAJC13 FOXK2 TTC28 PPP1R12A PSMD9 FASN RESF1 ZFHX4 LRBA GCN1 VCPIP1

3.00e-0649411013int:RCOR1
InteractionGJA1 interactions

FLNA ARHGAP32 ESYT1 SUN1 NBEA ERGIC2 ZDHHC8 HSD3B7 CANT1 VPS13A PALM LRBA HSD17B11

1.77e-0558311013int:GJA1
InteractionRAB3GAP1 interactions

ESYT1 ERGIC2 BCAR1 HSD3B7 FASN IFI44L HSD17B11

2.01e-051521107int:RAB3GAP1
InteractionPIGH interactions

DNAJC13 SPTLC2 ESYT1 SUN1 RDH10 FASN CANT1

2.91e-051611107int:PIGH
Cytoband19q13.41

ZNF600 ZNF888 ZNF578 ZNF468

4.02e-0578111419q13.41
Cytoband17q25

FOXK2 FASN FSCN2

1.18e-0439111317q25
GeneFamilyShort chain dehydrogenase/reductase superfamily

RDH10 HSD3B7 FASN HSD17B11

2.80e-0476754743
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG2 CRNN

3.52e-0477521350
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEA LRBA

6.00e-0497521230
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM2 CMYA5 TRIM3 TRIM32

6.54e-049575459
GeneFamilyAquaporins

AQP1 MIP

1.50e-0314752305
GeneFamilyAT-rich interaction domain containing

JARID2 ARID2

1.72e-0315752418
GeneFamilyCD molecules|Integrin alpha subunits

ITGA2B ITGA4

2.49e-03187521160
GeneFamilyBardet-Biedl syndrome associated|BBSome

TRIM32 BBS12

3.39e-0321752980
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

NBEA CMYA5

6.41e-0329752396
ToppCellsystemic_lupus_erythematosus-treated|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMCHD1 IFI44 PSMD9 ERGIC2 ITGA4 RESF1 EIF2S3 IFI44L

3.66e-0819811188165ff735095c52994fb5057d89be93cc378b7da
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PPP1R12A SMCHD1 IFI44 PSMD9 ERGIC2 ITGA4 RESF1 IFI44L

3.66e-0819811184c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellFetal_29-31_weeks-Immune-mast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CPB1 ITGA2B ITGA4 PKHD1L1 MMRN1 JARID2

1.73e-061451116dc89d817a9bef24a07e992efdab4136f12ceb399
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRERF1 IFI44 CDH23 TMEM62 IFI44L HSD17B11

2.65e-061561116f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MGAT4B SUN1 PTPRZ1 ZBED6 CHCHD2 PALM

5.13e-061751116e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP32 TRIM2 SUN1 RDH10 NBEA CMYA5

5.84e-0617911166e965e424eebef50f0202cff75f458be395cfca1
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

PPP1R12A SMCHD1 PPIG RESF1 ZNF45 ARID2

7.27e-06186111603db813598b67b1e08f759758a1c2023396921fa
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

7.50e-061871116f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMCHD1 EPG5 ZBED6 ARID2 LRBA SUCO

7.73e-061881116ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

8.21e-0619011160733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

8.46e-0619111165a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

8.46e-0619111160646cca78e24aeb6baa9934d3c439b797c567997
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

8.46e-0619111167f64add931b64b8d35836fa6bee9ebab593844d3
ToppCellCOVID-19-lung-CD4+_Treg|lung / Disease (COVID-19 only), tissue and cell type

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

8.46e-06191111673ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 NDUFAF6 CD96

8.98e-061931116af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

FLNA SMCHD1 IFI44 JARID2 IFI44L SIGLEC1

9.25e-061941116d1366b169d14011194e61d16b6b0953349febc78
ToppCellCOVID-19-lung-CD4+_T_cells_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

9.25e-0619411162a144a1c2d537c8a59aa419206ddd96c23f0aeab
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

SMCHD1 IFI44 JARID2 IFI44L SIGLEC1 OGA

9.80e-0619611163729d1444c65cad640377894decc64129bc3fd5b
ToppCellCOVID-19_Severe|World / disease group, cell group and cell class

IFI44 ITGA2B PKHD1L1 MMRN1 IFI44L SIGLEC1

9.80e-0619611163bedf60f662b373ad9d0f07d4da9f11864af3a74
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRRC66 KLF12 ADAMTS10 ZNF600 VPS13A LRBA

1.01e-051971116e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KLF12 SMCHD1 IFI44 VPS13A IFI44L LRBA

1.07e-051991116f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

FLNA SPTLC2 SMCHD1 IFI44 IFI44L SIGLEC1

1.07e-051991116c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

SMCHD1 IFI44 ITGA4 RESF1 IFI44L CD96

1.07e-051991116952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANKRD31 FLNA ITGA2B PKHD1L1 MMRN1 VPS13A

1.10e-052001116326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMCHD1 IFI44 ITGA4 RESF1 IFI44L SIGLEC1

1.10e-05200111612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 KLF12 SMCHD1 ITGA4 RESF1 CD96

1.10e-052001116510d84bf7a4621b079e5a7330d25e04508c84a49
ToppCellControl-PLT_3|Control / Disease Group and Platelet Clusters

FLNA MGAT4B MLEC ITGA2B MMRN1

2.67e-05140111582ea671f61d55f6896d903c5876b042e2f3385d6
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

SMCHD1 OBSCN RESF1 LRBA CD96

3.84e-051511115999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 IFI44 ITGA4 MSR1 SIGLEC1

3.84e-0515111153105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCellfacs-Lung-EPCAM-18m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA4 MSR1 JARID2 SIGLEC1 MSS51

5.05e-0516011157217730ae14840b935b3bf9aa49becbcbcd8a682
ToppCellfacs-Lung-EPCAM-18m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA4 MSR1 JARID2 SIGLEC1 MSS51

5.05e-051601115317ef81460c1a31b51119a6309b11be6a8d4ea3e
ToppCellfacs-Lung-EPCAM-18m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA4 MSR1 JARID2 SIGLEC1 MSS51

5.05e-051601115e6191240c93da34fc4431a35ef496edf323cb41e
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKHD1L1 MMRN1 HSD3B7 ZFHX4 PALM

5.36e-05162111596c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|356C / Donor, Lineage, Cell class and subclass (all cells)

EPG5 TUBGCP6 RESF1 ZNF45 CRNN

6.02e-051661115c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EPG5 TUBGCP6 RESF1 ZNF45 CRNN

7.12e-051721115a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellMS-CD8-proli_CD4|MS / Condition, Cell_class and T cell subcluster

SRR GTF3C4 TUBGCP6 ZBED6 CC2D2A

7.12e-0517211150b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCellMild-CD4+_T_Exhausted|World / Disease group and Cell class

LDHAL6A ESYT1 IFI44 ITGA4 IFI44L

7.12e-051721115efe68d9477aa873b1637ee689f298120303aa322
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EPG5 TUBGCP6 ZNF45 PDP1 CRNN

7.72e-051751115f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PKHD1L1 MMRN1 ZFHX4 ANKAR PALM

7.72e-05175111584d252f3e432231687613299bbea14978bb4b06b
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PKHD1L1 MMRN1 ZFHX4 ANKAR PALM

7.72e-051751115a00c6fa9b33640710dd05a3799031147196f0986
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PKHD1L1 MMRN1 HSD3B7 CRNN PALM

7.93e-051761115460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

DNAJC13 SUN1 ITGA4 ZBED6 ARID2

8.15e-05177111582fdd6185b368f54f03de389427cbe3071d21a99
ToppCellAdult-Immune-T_lymphocyte-D122|Adult / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

8.82e-05180111506c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TRERF1 ESYT1 CRPPA ITGA2B P2RX6

8.82e-051801115ac03812b1409435c55d323a7516deeac82bd3509
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SMCHD1 ARID2 VPS13A LRBA OGA

9.05e-051811115f2315414e714ac86211546a935660c4be6e85f1b
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

IFI44 EIF2S3B IFI44L OGA GCN1

9.29e-051821115877b6e611626628e709568747512f2827ebb2795
ToppCellNS-moderate-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAJC13 IFI44 MSR1 IFI44L SIGLEC1

9.29e-051821115e03e995e5fd14fc6a7559b83c0ca4e7ccc8e3d0f
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRPPA CPB1 BCAR1 AQP1 BBS12

1.00e-041851115efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRPPA CPB1 BCAR1 AQP1 BBS12

1.00e-041851115642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

TRERF1 KLF12 ITGA4 RESF1 CD96

1.00e-04185111502ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

SMCHD1 SUN1 ITGA4 ARID2 LRBA

1.03e-0418611158571956890fc9894d766ba294a28e376b4aba428
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

1.11e-041891115df30478b288084a1bd48f660409dcc784040897c
ToppCellCOVID-19-T_cells-CD8+_T_cells|COVID-19 / group, cell type (main and fine annotations)

TRERF1 KLF12 ITGA4 RESF1 CD96

1.11e-0418911152c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM2 MLEC AQP1 FASN CC2D2A

1.14e-04190111536e83995021ba16690f84e2077a9e8baec547d05
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLF12 SMCHD1 ITGA4 RESF1 CD96

1.14e-041901115d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CMYA5 PKHD1L1 MSR1 MMRN1 WDR49

1.14e-0419011159ce301841ce9486701fa28eb2a9929e35d476878
ToppCellIPF-Lymphoid-T_Cytotoxic|IPF / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.14e-041901115e5d0186bfb416a3eda76ac12b9379650afb6f409
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.14e-041901115d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AQP1 PKHD1L1 MMRN1 HSD3B7 PALM

1.14e-041901115a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 SMCHD1 ITGA4 RESF1 CD96

1.14e-041901115b772a5d281fe016f259ddda80d6f33d949dcac2b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM2 MLEC AQP1 FASN CC2D2A

1.14e-041901115d26be9e1b676f750e716b91ebc3598fac3735612
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AQP1 PKHD1L1 MMRN1 HSD3B7 PALM

1.14e-0419011150bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AQP1 PKHD1L1 MMRN1 HSD3B7 PALM

1.14e-04190111526e2237f65cb43723c5da853831b40df2982d6e4
ToppCellAdult-Immune-T_lymphocyte-D175|Adult / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

1.16e-0419111150b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SMCHD1 SUN1 ITGA4 ARID2 LRBA

1.16e-0419111159454f642c3621370fa23640b631301346b300950
ToppCellCOVID-19-lung-CD8+_T_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 KLF12 ITGA4 RESF1 CD96

1.16e-041911115543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

1.16e-041911115c7be771543089fc94e5c62fd22f745189642aec3
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th17|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ESYT1 IFI44 RESF1 IFI44L CD96

1.16e-041911115b3ed4797a7a9810cf3507e0d0f23f45c35bd8ba2
ToppCellCOPD-Lymphoid-T_Cytotoxic|World / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.19e-0419211155bfd9f5d47511441eb2d3cc3c4d7ed330ffd0bd1
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 IFI44 ITGA2B MMRN1 HSD3B7

1.19e-041921115959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.19e-041921115eb4909574fb5fc91399463523e2737095773200a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMCHD1 ERGIC2 RESF1 IFI44L CD96

1.19e-041921115e07b6892276c81c1227e94ca942f6820d89a7ca3
ToppCellCOPD-Lymphoid|COPD / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.19e-041921115064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.19e-041921115b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ITGA2B CMYA5 PKHD1L1 MMRN1 ZFHX4

1.19e-041921115d43caf42ec744e895137f31ef65a990e250669d2
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SMCHD1 IFI44 RESF1 IFI44L CD96

1.22e-0419311152901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCellCOPD-Lymphoid-T_Cytotoxic|COPD / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.22e-04193111558e94fe2e89cdafc6974938f97a4c162061a437d
ToppCellCOVID-19-lung-CD4+_T_cells_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 SMCHD1 ITGA4 RESF1 CD96

1.22e-041931115326fd2ce2c4b51e5a38f2a7a09f22f8f0e92735a
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMCHD1 AQP1 VPS13A IFI44L LRBA

1.22e-0419311159337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SMCHD1 IFI44 RESF1 IFI44L CD96

1.22e-041931115f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCellIPF-Lymphoid|IPF / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.22e-041931115bf9d50aea909a28dd1d0933af33842d5f1ae7818
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA2B CMYA5 PKHD1L1 MMRN1 PALM

1.22e-041931115bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellAdult-Immune-T_lymphocyte|Adult / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

1.22e-04193111526df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCellIPF-Lymphoid-T_Cytotoxic|World / Disease state, Lineage and Cell class

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.22e-04193111535c902a983d7f1156a74fe68ee366609029833b3
ToppCellCOVID-19-kidney-T-cells-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 KLF12 ITGA4 RESF1 CD96

1.22e-0419311155b84fa640cf30dea55fde53b810f850ff946d253
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SMCHD1 IFI44 RESF1 IFI44L CD96

1.22e-041931115f8af695457d2a0a911a5ac491742465864ebda37
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SMCHD1 IFI44 RESF1 IFI44L CD96

1.22e-041931115089aece40130034a89a5213be778f10b0787eeba
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

1.22e-041931115b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KLF12 SMCHD1 ITGA4 RESF1 CD96

1.25e-0419411153d6f2d190dd50804afea299957cc44c2bb756134
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMCHD1 ERGIC2 RESF1 IFI44L CD96

1.25e-0419411150b0042b6a356a49a059fb64a1e1abb25c82d48cf
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

1.25e-0419411155c1dca33f382f37a7deb23e573578343c3b54986
ToppCellImmune-T_lymphocyte|World / Lineage, Cell type, age group and donor

TRERF1 KLF12 ITGA4 RESF1 CD96

1.25e-041941115f47fa18c87b35a3960557f8169ff7830dd6ecb80
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ITGA4 VPS13A WDR89 LRBA CD96

1.28e-0419511154b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CPB1 CMYA5 PKHD1L1 ZFHX4 PTPRZ1

1.28e-041951115a52685f76eca269a7d2de8dfc317439483e233fa
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.28e-041951115ffb40486f8097b2c08e8f3b3685d0b8cb8d1bc66
ToppCellnucseq-Immune-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TRERF1 KLF12 SMCHD1 ITGA4 CD96

1.28e-041951115b8124e8a23e6d37b40023608674e67285c6ffe84
ToppCellPBMC-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

SPTLC2 IFI44 ITGA4 IFI44L SIGLEC1

1.28e-041951115674355ca00314bde90ef7f6ddb83afe2d5323130
ToppCellcontrol-Lymphoid-Treg|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IFI44 ITGA4 ANKAR IFI44L CD96

1.28e-04195111566959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCellNS-moderate-d_07-13|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RDH10 SBSN CRNN IFI44L SIGLEC1

1.28e-041951115088209505a68519ec89f50f0576096da6966bf17
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KLF12 SMCHD1 RESF1 IFI44L CD96

1.28e-04195111522191d361af136942508f1553ff41a626ed982ad
Diseaseautosomal recessive limb-girdle muscular dystrophy type 2H (implicated_via_orthology)

TRIM2 TRIM3 TRIM32

5.18e-0831113DOID:0110282 (implicated_via_orthology)
Diseasegalectin-3-binding protein measurement

MSR1 CANT1 SIGLEC1

1.03e-0661113EFO_0010241
DiseaseMEHMO syndrome (implicated_via_orthology)

EIF2S3B EIF2S3

1.40e-0521112DOID:0060801 (implicated_via_orthology)
Diseaseautosomal recessive limb-girdle muscular dystrophy (implicated_via_orthology)

TRIM2 TRIM3

4.20e-0531112DOID:0110274 (implicated_via_orthology)
Diseasefrontotemporal dementia and/or amyotrophic lateral sclerosis-2 (implicated_via_orthology)

CHCHD2 CHCHD2P9

4.20e-0531112DOID:0060214 (implicated_via_orthology)
DiseaseParkinson's disease 22 (implicated_via_orthology)

CHCHD2 CHCHD2P9

4.20e-0531112DOID:0080504 (implicated_via_orthology)
Diseasespinal muscular atrophy, Jokela type (implicated_via_orthology)

CHCHD2 CHCHD2P9

4.20e-0531112DOID:0081356 (implicated_via_orthology)
Diseasehypopituitarism (implicated_via_orthology)

EIF2S3B EIF2S3

2.08e-0461112DOID:9406 (implicated_via_orthology)
Diseasepsoriasis (implicated_via_orthology)

SPTLC2 LTBR

2.91e-0471112DOID:8893 (implicated_via_orthology)
Diseaseleukodystrophy (implicated_via_orthology)

EIF2S3B EIF2S3

4.96e-0491112DOID:10579 (implicated_via_orthology)
Diseasetriacylglycerol 56:2 measurement

ZFHX4 SLC5A12

7.54e-04111112EFO_0010429
DiseaseCiliopathies

CDH23 TRIM32 CC2D2A BBS12

8.06e-041101114C4277690
Diseasegranulins measurement

CDH23 ITGA2B

9.03e-04121112EFO_0008141
DiseaseInfluenza

IFI44 IFI44L SIGLEC1

1.00e-03521113C0021400
DiseasePolydactyly

TRIM32 CC2D2A BBS12 CD96

1.01e-031171114C0152427
Diseaselymphocyte measurement

TTC28 ARID2 NDUFAF6 LTBR

1.01e-031171114EFO_0803546
DiseasePneumoconiosis

CDH23 PTPRZ1

1.24e-03141112C0032273
DiseaseBagassosis

CDH23 PTPRZ1

1.24e-03141112C0004681
DiseaseDisorder of eye

CDH23 TRIM32 FSCN2 CC2D2A BBS12

1.26e-032121115C0015397
DiseaseBardet-Biedl syndrome 1 (disorder)

TRIM32 BBS12

1.84e-03171112C2936862
DiseaseSchizophrenia

KLF12 ARHGAP32 SRR CMYA5 ZDHHC8 JARID2 PTPRZ1 AGA SLC17A7 MSS51

1.86e-0388311110C0036341
DiseaseBardet-Biedl syndrome

TRIM32 BBS12

2.06e-03181112cv:C0752166
Diseaseaspartate aminotransferase measurement

ANKRD31 DNAJC13 TTC28 SUN1 OBSCN L2HGDH LTBR LRBA GCN1 MMUT

2.20e-0390411110EFO_0004736
Diseaseplatelet-to-lymphocyte ratio

KLF12 TTC28 CDH23 ITGA2B ITGA4 LTBR

2.55e-033631116EFO_0008446
Diseasemuscular dystrophy (implicated_via_orthology)

TRIM2 TRIM3

2.81e-03211112DOID:9884 (implicated_via_orthology)
DiseaseParkinson's disease (implicated_via_orthology)

VPS13A CHCHD2 SLC17A7 CHCHD2P9

2.97e-031571114DOID:14330 (implicated_via_orthology)
Diseaseprogranulin measurement

CDH23 ITGA2B

3.08e-03221112EFO_0004625
Diseaselymphocyte percentage of leukocytes

KLF12 TTC28 CDH23 ITGA4 FASN NDUFAF6 LTBR BBS12

3.69e-036651118EFO_0007993

Protein segments in the cluster

PeptideGeneStartEntry
KIDGVHLGQAVHVSG

TMEM62

356

Q0P6H9
IQVGQHGHSSVEDAT

AEN

246

Q8WTP8
GILVSQHSGVEAHSH

ESYT1

911

Q9BSJ8
KVAQHLTGASHGDNV

EPG5

1106

Q9HCE0
VHQTLVAHGQALDAG

BCAR1

551

P56945
AVAGAHVVIHTAGLV

HSD3B7

76

Q9H2F3
ERIINHAAGSHGVSG

ERGIC2

276

Q96RQ1
SSSNGQAHIHVVGVK

ARID2

586

Q68CP9
ATLAQSVGHISGAHL

AQP1

61

P29972
ALLENGAHVNGVTVH

ASB11

116

Q8WXH4
KNNHGHIVTVASAAG

HSD17B11

161

Q8NBQ5
TDSEIITGHGHTQIN

BBS12

686

Q6ZW61
GIHVVHGSTGTLLAT

CDH23

3281

Q9H251
VAVGSAVGHTLGHAI

CHCHD2

66

Q9Y6H1
GHLQGQASTSHVAIS

ADAMTS10

126

Q9H324
VQSVGHISGAHVNPA

MIP

56

P30301
KVVHAVDGTAENGIH

PALM

211

O75781
HGQSVITVIGGEEHF

RAB11FIP3

376

O75154
NHVKVTSEALGHAGR

CRPPA

311

A4D126
VGTNNHGHTAEQVTG

PAFAH1B3

101

Q15102
HGHTAEQVTGGIKAI

PAFAH1B3

106

Q15102
THKSAVHALVEAGGI

ANKAR

771

Q7Z5J8
AHQGIAVLGSDTVHQ

ANKRD31

1636

Q8N7Z5
HGQAGSQHGESESIV

FLG2

1826

Q5D862
AGQTITVATHAKQGA

NFRKB

1101

Q6P4R8
FQHVGTHSSLAGKIQ

MGAT4B

366

Q9UQ53
AVHQTGHNSGVIHSG

L2HGDH

86

Q9H9P8
GGSTVHVVGASHVET

MSS51

261

Q4VC12
TQNGTHVASVPTAVH

FOXK2

576

Q01167
IHTNQAESHTAVGRG

MMRN1

291

Q13201
AVNAGGEAHVDVHGI

MLEC

51

Q14165
SVKSIFHGHVTGQAV

IFI44L

216

Q53G44
FHGHVTGQAVVGSDI

IFI44L

221

Q53G44
AVSHVGAVVPTHGFS

CANT1

331

Q8WVQ1
DHAASHIGKAQGIVT

NDUFAF6

201

Q330K2
THTGQVLGSLVHVKG

CES2

36

O00748
VHTSVHGVGHSFVQS

PGM2

251

Q96G03
HSIQSAMHSIGGVQV

LRBA

461

P50851
IHGHVSNASIRVGEN

TUBGCP6

1106

Q96RT7
SVLSGIGSVSHHVVS

GCN1

361

Q92616
VSTDHSVPIGNGHVA

PTPRZ1

1361

P23471
KAVASGQTQTGAVTH

ARHGAP32

1001

A7KAX9
VAHVDGVDLHVANTG

PDP1

276

Q9P0J1
AVTGGHAQIQAGTHT

CRNN

281

Q9UBG3
AVTGGHTQIQAGSHT

CRNN

341

Q9UBG3
THLIGNIKQGHGTES

ITFG2

256

Q969R8
HSVGVSSVAGTSHAV

LRRC66

551

Q68CR7
VQAVHKAAHFGQGTG

MSR1

396

P21757
GHHVVFGQVISGQEV

PPIG

136

Q13427
GDTHTLTVHGAQVLD

OBSCN

1771

Q5VST9
VAVGSAVGHTQGHAV

CHCHD2P9

66

Q5T1J5
QGHVTHQALVGTNTT

IFI44

211

Q8TCB0
IFVVGGHNGVSHLSS

KLHL28

481

Q9NXS3
SNQHVTLDHEGVGSG

CC2D2A

766

Q9P2K1
TGTHKVTVLFAGQHI

FLNA

351

P21333
HVAVTVGGSNGHFEL

FH

391

P07954
LHSASSGVEKQVEHG

CMYA5

1316

Q8N3K9
GSHVSTAAVVREQHG

LDHD

41

Q86WU2
NSHVDHGTGALVISS

DNAJC13

516

O75165
GAGHFRSQHTTEVVG

ITGA4

256

P13612
VIHKTGHIAAGTSTN

AGA

211

P20933
SASGVGGQQFLHIIH

KLF12

151

Q9Y4X4
TINIGTIGHVAHGKS

EIF2S3B

41

Q2VIR3
VTVAGGVHISGLHTE

FASN

1086

P49327
GQGVHHAASQFGKET

SBSN

351

Q6UWP8
FGQGVHHAASQVGKE

SBSN

386

Q6UWP8
AVQGFHTGVHQAGKE

SBSN

476

Q6UWP8
VLVTVALASAHHGGE

CPB1

6

P15086
ASVIAVTIQGGAHHL

DPP7

431

Q9UHL4
THSHGVKTGQCVVFN

P2RX6

151

O15547
VAVHCGKVDTNTHGS

JARID2

861

Q92833
VTHGGIHATATQVSA

FSCN2

316

O14926
QSLHNIGSVVQHSEG

PSMD9

171

O00233
QNEHHLEGGFSIGSV

TRIM32

541

Q13049
SGNKEIISHISQHGG

SMCHD1

756

A6NHR9
QVAHSGAKASVVDGT

OGA

401

O60502
GGVPSVSHVTHARHQ

RGP1

276

Q92546
HIGATVSHQTDFGAN

RESF1

131

Q9HCM1
THSIHSAIHSIGGIQ

NBEA

486

Q8NFP9
ARHNIAGTTHSGAEK

PTPN12

651

Q05209
VNNSTTHRGGHVVVQ

SLC17A7

91

Q9P2U7
THRGGHVVVQKAQFS

SLC17A7

96

Q9P2U7
PKAVVTHSSGNHGQA

SRR

76

Q9GZT4
GHSVAVTDVNGDGRH

ITGA2B

321

P08514
EINHGHIVTVASSLG

RDH10

186

Q8IZV5
IGSGGSSHREIHVKQ

SPATA4

271

Q8NEY3
HVAGGHSIAANVNSP

ZFHX4

1586

Q86UP3
GEVGTGHSSLNTHIR

ZNF20

111

P17024
GQNSTLVIHKAIHTG

ZNF578

381

Q96N58
ASHHSGGATVVTAAV

VPS13A

1366

Q96RL7
ANGSTKTNHVHITGI

CD96

496

P40200
AAAAAAAGQIHHVTQ

SPTLC2

36

O15270
HHTLNVGQDGAVDIS

WDR49

226

Q8IV35
GVHSLASGTGHVQVA

SIGLEC1

1391

Q9BZZ2
NIVIASTGHRHSQGE

PKHD1L1

2326

Q86WI1
VGQHIENVSSSHGKG

SUCO

196

Q9UBS9
ISKAGLNVHNSHVTG

GTF3C4

406

Q9UKN8
EGGQSAAAHSAHTVK

VCPIP1

856

Q96JH7
GEQSQVAHGTNGIHV

LTBR

336

P36941
AQSTLIHHQAIHGVG

ZNF888

701

P0CJ79
VVGQELLTAGHHGAS

TTC28

201

Q96AY4
SSNVVHAIKDGGFTH

ZBED6

566

P86452
SSALIQHQGVHTGDK

ZNF16

501

P17020
VLNHAEGLGAAHTTI

ZDHHC8

171

Q9ULC8
HVSRQVTSSGVSHGG

SUN1

106

O94901
THVTSLQGGHAATVR

WDR89

311

Q96FK6
LTSDGHVVVADSGNH

TRIM2

721

Q9C040
IQGSTHAGGFHNVLE

SLC5A12

201

Q1EHB4
GQNSALVIHKAIHTG

ZNF600

256

Q6ZNG1
TGQGNTEVIHTGTLH

ZNF468

61

Q5VIY5
VGSHLQAHQISHTGE

ZNF45

371

Q02386
LTSDGHVVVADAGNH

TRIM3

721

O75382
NGHARIHGGTNQVTK

TRERF1

1031

Q96PN7
TINIGTIGHVAHGKS

EIF2S3

41

P41091
EAIHHNKISIVGTGS

LDHAL6A

16

Q6ZMR3
VHAVGISTLAAGHKT

MMUT

666

P22033
NDVRHAKSGGTALHV

PPP1R12A

191

O14974