Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncadherin binding

RARS1 ANK3 CD2AP ITGA6 FMNL2 PTPN11 RUVBL1 SND1 PI4KA CTNNA3 NUMB MACF1 VCL HDLBP

1.08e-0833911614GO:0045296
GeneOntologyMolecularFunctioncell adhesion molecule binding

RARS1 ANK3 CD2AP ITGA6 FMNL2 PTPN11 RUVBL1 SND1 PI4KA CTNNA3 NUMB MACF1 VCL HDLBP

9.98e-0659911614GO:0050839
GeneOntologyMolecularFunctionactin filament binding

CD2AP FMNL2 XIRP2 SIPA1L1 CTNNA3 MACF1 VCL

3.65e-042271167GO:0051015
GeneOntologyMolecularFunctionactin binding

CD2AP FMNL2 OPHN1 CCDC88A XIRP2 SIPA1L1 CTNNA3 FMN2 MACF1 VCL

4.85e-0447911610GO:0003779
GeneOntologyMolecularFunctionsulfur compound binding

COL11A2 HPSE2 CD34 LPL OGDHL CCL7 CCL8 FGFBP1

6.02e-043231168GO:1901681
GeneOntologyMolecularFunctioncytoskeletal protein binding

ANK3 CD2AP CLSTN1 FMNL2 OPHN1 PPP2R2A CCDC88A XIRP2 SBDS SIPA1L1 CTNNA3 RACGAP1 FMN2 MACF1 KIF13A VCL

6.15e-04109911616GO:0008092
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RALGDS RHOD TRIO RANBP3 ARHGAP11A OPHN1 CCDC88A RALBP1 SIPA1L1 RACGAP1

7.52e-0450711610GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RALGDS RHOD TRIO RANBP3 ARHGAP11A OPHN1 CCDC88A RALBP1 SIPA1L1 RACGAP1

7.52e-0450711610GO:0030695
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V1B2 PSMC3 ATP8B1 DNAH14 LONP1 FBH1 RUVBL1 RALBP1 MACF1 ABCC12 KIF13A

9.02e-0461411611GO:0140657
GeneOntologyMolecularFunctionCCR2 chemokine receptor binding

CCL7 CCL8

9.16e-0481162GO:0031727
GeneOntologyBiologicalProcesseosinophil chemotaxis

DAPK2 CCL7 CCL8 CCL13

2.25e-05301154GO:0048245
GeneOntologyBiologicalProcesscell-substrate junction assembly

RHOD ITGA6 SLC9A1 PTPN11 MACF1 VCL

3.17e-051081156GO:0007044
GeneOntologyBiologicalProcesseosinophil migration

DAPK2 CCL7 CCL8 CCL13

3.74e-05341154GO:0072677
GeneOntologyBiologicalProcessregulation of focal adhesion assembly

RHOD SLC9A1 PTPN11 MACF1 VCL

4.48e-05701155GO:0051893
GeneOntologyBiologicalProcessregulation of cell-substrate junction assembly

RHOD SLC9A1 PTPN11 MACF1 VCL

4.48e-05701155GO:0090109
GeneOntologyBiologicalProcesscell-substrate junction organization

RHOD ITGA6 SLC9A1 PTPN11 MACF1 VCL

4.52e-051151156GO:0150115
GeneOntologyBiologicalProcessregulation of cell-substrate junction organization

RHOD SLC9A1 PTPN11 MACF1 VCL

6.24e-05751155GO:0150116
GeneOntologyBiologicalProcessmaintenance of protein location in membrane

ANK3 CCDC88A

9.21e-0531152GO:0072658
GeneOntologyBiologicalProcessmaintenance of protein location in plasma membrane

ANK3 CCDC88A

9.21e-0531152GO:0072660
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

RHOD TRIO CD2AP ARHGAP11A OPHN1 ADRA1A RALBP1 SIPA1L1 RACGAP1

1.05e-043331159GO:0051056
GeneOntologyBiologicalProcesspositive regulation of action potential

ANK3 ADRA1A SLC9A1

1.30e-04181153GO:0045760
GeneOntologyBiologicalProcessfocal adhesion assembly

RHOD SLC9A1 PTPN11 MACF1 VCL

2.11e-04971155GO:0048041
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

RALGDS RHOD TRIO CD2AP ARHGAP11A OPHN1 ADRA1A CCDC88A RALBP1 SIPA1L1 RACGAP1

2.12e-0453811511GO:0007264
GeneOntologyCellularComponentprotein phosphatase type 2A complex

PPP2R2D PPP2R2A PPP2R2B

1.25e-04181153GO:0000159
DomainPP2A_PR55_CS

PPP2R2D PPP2R2A PPP2R2B

8.82e-0741143IPR018067
DomainPP2A_PR55

PPP2R2D PPP2R2A PPP2R2B

8.82e-0741143IPR000009
DomainPR55_2

PPP2R2D PPP2R2A PPP2R2B

8.82e-0741143PS01025
DomainPR55_1

PPP2R2D PPP2R2A PPP2R2B

8.82e-0741143PS01024
DomainRibosomal_L3

RPL3 RPL3L

1.10e-0431142IPR000597
DomainRIBOSOMAL_L3

RPL3 RPL3L

1.10e-0431142PS00474
DomainRibosomal_L3

RPL3 RPL3L

1.10e-0431142PF00297
DomainRibosomal_L3_CS

RPL3 RPL3L

1.10e-0431142IPR019926
DomainRho_GTPase_activation_prot

ARHGAP11A OPHN1 RALBP1 RACGAP1 PLXNA1

2.03e-04881145IPR008936
DomainCX3CL1

CCL8 CCL13

2.20e-0441142IPR008097
DomainVINCULIN_1

CTNNA3 VCL

2.20e-0441142PS00663
DomainVinculin_CS

CTNNA3 VCL

2.20e-0441142IPR000633
DomainVinculin

CTNNA3 VCL

3.65e-0451142PF01044
DomainSMALL_CYTOKINES_CC

CCL7 CCL8 CCL13

5.20e-04261143PS00472
DomainChemokine_CC_CS

CCL7 CCL8 CCL13

5.20e-04261143IPR000827
DomainRhoGAP

ARHGAP11A OPHN1 RALBP1 RACGAP1

5.59e-04621144SM00324
DomainRhoGAP

ARHGAP11A OPHN1 RALBP1 RACGAP1

5.94e-04631144PF00620
DomainRhoGAP_dom

ARHGAP11A OPHN1 RALBP1 RACGAP1

6.31e-04641144IPR000198
DomainRHOGAP

ARHGAP11A OPHN1 RALBP1 RACGAP1

6.31e-04641144PS50238
Domain-

ARHGAP11A OPHN1 RALBP1 RACGAP1

6.31e-046411441.10.555.10
DomainVinculin/catenin

CTNNA3 VCL

7.60e-0471142IPR006077
DomainSCY

CCL7 CCL8 CCL13

2.14e-03421143SM00199
DomainChemokine_IL8-like_dom

CCL7 CCL8 CCL13

2.44e-03441143IPR001811
DomainIL8

CCL7 CCL8 CCL13

2.44e-03441143PF00048
DomainFH2

FMNL2 FMN2

3.68e-03151142PS51444
DomainFH2_Formin

FMNL2 FMN2

3.68e-03151142IPR015425
DomainFH2

FMNL2 FMN2

3.68e-03151142PF02181
DomainFH2

FMNL2 FMN2

3.68e-03151142SM00498
DomainAAA

PSMC3 LONP1 RUVBL1

3.94e-03521143PF00004
DomainATPase_AAA_core

PSMC3 LONP1 RUVBL1

4.38e-03541143IPR003959
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ATP6V1B2 ANK3 TRIO PPP2R2D NSD2 CDKN2AIP PSMC3 ITGA6 XPO4 PPP2R2A LONP1 PTPN11 CCDC88A TTC7B PI4KA FMN2 NUMB HDLBP ILKAP

2.01e-0910491161927880917
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

RARS1 ANK3 CD2AP ITGA6 FMNL2 SLC9A1 RUVBL1 SND1 PI4KA NUMB MACF1 VCL HDLBP

5.73e-085651161325468996
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

TRIO PPP2R2D PSMC3 TUB OPHN1 PPP2R2A TTC7B PI4KA SIPA1L1 FMN2 RPL3 HDLBP

7.00e-084751161231040226
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

ATP6V1B2 RARS1 WWC3 PSMA6 ETFA PSMC3 PRPF8 RUVBL1 SND1 SBDS TRPM1 RPL3 VCL HDLBP GULP1

7.87e-088031161536517590
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

RARS1 RANBP3 CD2AP PRPF8 CCDC88A RUVBL1 SND1 RPL3 HDLBP

2.12e-07256116933397691
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RARS1 TRIO NSD2 PSMA6 ETFA WDR46 PSMC3 PRPF8 PPP2R2A LONP1 PTPN11 RUVBL1 SND1 PI4KA RACGAP1 RPL3 PLXNA1 VCL HDLBP

2.55e-0714251161930948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1B2 ANK3 TRIO PSMA6 PSMC3 GRM5 FMNL2 OPHN1 PPP2R2A LONP1 TTC7B SND1 PI4KA SIPA1L1 OGDHL MACF1 RPL3 VCL HDLBP

2.71e-0714311161937142655
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

RARS1 ETFA PSMC3 PRPF8 PPP2R2A RUVBL1 PI4KA RPL3

3.46e-07197116831620119
Pubmed

Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx.

CCL7 CCL8 CCL13

3.60e-075116318660381
Pubmed

Identification of new regulatory sequences far upstream of the mouse monocyte chemoattractant protein-1 gene.

CCL7 CCL8 CCL13

3.60e-075116311735217
Pubmed

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.

PSMA6 PRPF8 DNAH14 ZNF462 RUVBL1 NUMB CAPN5 UROD RPL3L HDLBP ILKAP

4.64e-074631161127503909
Pubmed

CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines.

CCL7 CCL8 CCL13

7.18e-076116310734104
Pubmed

Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.

CCL7 CCL8 CCL13

7.18e-07611638996246
Pubmed

A CCL8 gradient drives breast cancer cell dissemination.

CCL7 CCL8 CCL13

7.18e-076116327181207
Pubmed

A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.

ETFA PSMC3 PRPF8 PTPN11 RACGAP1

7.86e-0751116526839216
Pubmed

HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.

PPP2R2D PPP2R2A PPP2R2B

1.25e-067116325816751
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

MRC1 ANK3 HPSE2 CFAP43 CREM FBH1 CTNNA3 OGDHL HABP2 VCL

1.39e-064151161016385451
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

ATP6V1B2 RARS1 RANBP3 CD2AP PSMA6 ETFA PSMC3 PPP2R2A PTPN11 RUVBL1 SND1 SBDS MACF1 UROD KIF13A RPL3 VCL HDLBP

1.59e-0614551161822863883
Pubmed

Tagging genes with cassette-exchange sites.

COL11A2 RARS1 PPP2R2D XPO4 ZNF462 PPP2R2A PTPN11 MACF1 PLXNA1

1.98e-06335116915741177
Pubmed

CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.

CCL7 CCL8 CCL13

2.00e-068116310477718
Pubmed

Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis.

CCL7 CCL8 CCL13

2.00e-068116319865101
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RANBP3 CDKN2AIP PSMA6 ETFA PRPF8 PTPN11 RUVBL1 SND1 NUMB MACF1 RPL3 VCL HDLBP ILKAP

2.95e-069341161433916271
Pubmed

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.

PPP2R2D PPP2R2A PPP2R2B

2.99e-069116319762425
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

RARS1 ANK3 PPP2R2D PSMA6 ETFA PSMC3 PRPF8 RUVBL1 SND1 MACF1 RPL3 VCL HDLBP

3.14e-068071161330575818
Pubmed

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.

IL12RB2 REL CCL7 CCL8 CCL13

3.34e-0668116522412388
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ANK3 CD2AP PSMA6 PTPN11 CCDC88A RUVBL1 SND1 NUMB MACF1 RPL3 VCL HDLBP

4.61e-067081161239231216
Pubmed

Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo.

CCL7 CCL8 CCL13

7.78e-0612116312149192
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

RARS1 CDKN2AIP PSMA6 PSMC3 PPP2R2A CCDC88A RUVBL1 SIPA1L1 VCL

8.14e-06399116937536630
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

PSMA6 WDR46 PSMC3 PRPF8 RUVBL1 SND1

9.26e-06144116635681168
Pubmed

Cloning and characterization of a novel promiscuous human beta-chemokine receptor D6.

CCL7 CCL8 CCL13

1.01e-051311639405404
Pubmed

A proteomics and transcriptomics approach to identify leukemic stem cell (LSC) markers.

ITGA6 CD34

1.10e-052116223233446
Pubmed

CD34 and CD49f Double-Positive and Lineage Marker-Negative Cells Isolated from Human Myometrium Exhibit Stem Cell-Like Properties Involved in Pregnancy-Induced Uterine Remodeling.

ITGA6 CD34

1.10e-052116226108791
Pubmed

Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication.

PPP2R2A PPP2R2B

1.10e-052116224244166
Pubmed

A novel ribosomal protein L3-like gene (RPL3L) maps to the autosomal dominant polycystic kidney disease gene region.

RPL3 RPL3L

1.10e-05211628921388
Pubmed

Insulin inhibits Na+/H+ exchange in vascular smooth muscle and endothelial cells in situ: involvement of H2O2 and tyrosine phosphatase SHP-2.

SLC9A1 PTPN11

1.10e-052116219036852
Pubmed

Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling.

PPP2R2D PPP2R2A

1.10e-052116218697906
Pubmed

Different roles of Numb-p72 and Numb-p65 on the trafficking of metabotropic glutamate receptor 5.

GRM5 NUMB

1.10e-052116233394235
Pubmed

Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family.

CCL7 CCL8

1.10e-05211621613466
Pubmed

RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function.

RPL3 RPL3L

1.10e-052116237080962
Pubmed

Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse.

RHOD PLXNA1

1.10e-052116211784792
Pubmed

NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity.

REL GRM5

1.10e-052116215818410
Pubmed

Expression of Muscle-Specific Ribosomal Protein L3-Like Impairs Myotube Growth.

RPL3 RPL3L

1.10e-052116226684695
Pubmed

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.

RPL3 RPL3L

1.10e-052116236882085
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

PPP2R2D PSMC3 PPP2R2A PPP2R2B RUVBL1

1.12e-0587116517148452
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

RARS1 PPP2R2D PSMA6 ETFA PSMC3 XPO4 PPP2R2A PPP2R2B RUVBL1 RPL3 VCL

1.14e-056471161126618866
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

PSMA6 HPSE2 PRPF8 PTPN11 SND1 HDLBP ILKAP

1.31e-05231116736597993
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

RARS1 ARID4A NSD2 WDR46 ARHGAP11A DNAH14 SLC9A1 FBH1 DTWD2 NUMB UROD KIF13A RPL3

1.35e-059251161328986522
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

CDKN2AIP PSMA6 PSMC3 SLFN5 PRPF8 RUVBL1 PI4KA MACF1 RPL3 VCL

1.36e-055381161028524877
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

RARS1 ANK3 RANBP3 CD2AP PTPN11 RUVBL1 SND1 NUMB VCL HDLBP

1.62e-055491161038280479
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

RNMT RARS1 CDKN2AIP PSMA6 PRPF8 PPP2R2A CCDC88A RUVBL1 SND1 RPL3

1.67e-055511161034728620
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ATP6V1B2 RARS1 WWC3 ETFA PSMC3 PRPF8 PPP2R2A LONP1 UBL5 RUVBL1 SIPA1L1 RACGAP1 RPL3 VCL HDLBP

1.78e-0512471161527684187
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

ATP6V1B2 RARS1 CD2AP PSMA6 PRPF8 PTPN11 SND1 PI4KA MACF1 RPL3 VCL

2.58e-057071161119738201
Pubmed

Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.

RARS1 PPP2R2D ETFA PRPF8 PPP2R2A RUVBL1 RPL3

2.67e-05258116721081666
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

RARS1 CDKN2AIP ETFA PSMC3 PRPF8 LONP1 RUVBL1 NUMB MACF1 RPL3 HDLBP

2.72e-057111161133022573
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

RARS1 TRIO PSMA6 ITGA6 PRPF8 NUMB MACF1 RPL3

2.82e-05358116832460013
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

CD2AP WDR46 PRPF8 PPP2R2A RUVBL1 SND1 SBDS RACGAP1 MACF1 VCL HDLBP

3.20e-057241161136232890
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TRIO RANBP3 DAPK2 CD2AP CCDC88A PI4KA SIPA1L1 RACGAP1 FMN2 NUMB MACF1 KIF13A

3.21e-058611161236931259
Pubmed

Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform.

PPP2R2A PPP2R2B

3.30e-05311621849734
Pubmed

A critical role for SHP2 in STAT5 activation and growth factor-mediated proliferation, survival, and differentiation of human CD34+ cells.

PTPN11 CD34

3.30e-053116221670473
Pubmed

Structural characterization of a monomeric chemokine: monocyte chemoattractant protein-3.

CCL7 CCL8

3.30e-05311628898111
Pubmed

Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers.

ARHGAP11A RACGAP1

3.30e-053116227216196
Pubmed

Morphine has an antinociceptive effect through activation of the okadaic-acid-sensitive Ser/Thr protein phosphatases PP 2 A and PP5 estimated by tail-pinch test in mice.

PPP2R2A PPP2R2B

3.30e-053116216102737
Pubmed

FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination.

PSMA6 PSMC3

3.30e-053116222072791
Pubmed

Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.

PPP2R2A PPP2R2B

3.30e-05311629514514
Pubmed

Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.

CCL7 CCL8 CCL13

3.37e-0519116310438970
Pubmed

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development.

PPP2R2D PPP2R2A PPP2R2B

3.37e-0519116332582689
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATP6V1B2 ANK3 RANBP3 ETFA DNAJC27 PRPF8 C5orf34 CCDC88A SND1 DNAJA4 PI4KA NUMB MACF1 RPL3 VCL HDLBP

3.55e-0514871161633957083
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

RARS1 CDKL2 SLFN5 ARHGAP11A PRPF8 FMNL2 DNAH14 MIPOL1 ADRA1A PI4KA FMN2

3.72e-057361161129676528
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ATP6V1B2 RARS1 ETFA WDR46 PRPF8 LONP1 RUVBL1 SND1 PI4KA RACGAP1 MACF1 RPL3 HDLBP

3.88e-0510241161324711643
Pubmed

A 2-Mb YAC/BAC-based physical map of the ovum mutant (Om) locus region on mouse chromosome 11.

CCL7 CCL8 CCL13

3.95e-0520116310995569
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RARS1 PSMA6 WDR46 PSMC3 PRPF8 LONP1 RUVBL1 SND1 SBDS PI4KA RACGAP1 MACF1 RPL3 VCL HDLBP

4.54e-0513531161529467282
Pubmed

Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.

RARS1 PSMA6 PSMC3 CCDC88A RUVBL1 SND1 RPL3 HDLBP

4.62e-05384116831059266
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

ITGA6 SLC9A1 PI4KA NUMB CAPN5 RPL3 VCL

5.02e-05285116721423176
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RNMT RANBP3 CD2AP PSMA6 ETFA ITGA6 PRPF8 PPP2R2A PTPN11 RUVBL1 SND1 NUMB VCL HDLBP ILKAP

5.10e-0513671161532687490
Pubmed

A protein interaction landscape of breast cancer.

ANK3 TRIO CDKN2AIP LONP1 SND1 SBDS PI4KA MACF1 RPL3 HDLBP

5.45e-056341161034591612
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

RALGDS ATP6V1B2 TRIO PSMA6 ETFA PSMC3 REL PRPF8 MIPOL1 RUVBL1 SBDS SIPA1L1

6.18e-059221161227609421
Pubmed

The CCL2/CCL7/CCL12/CCR2 pathway is substantially and persistently upregulated in mice after traumatic brain injury, and CCL2 modulates the complement system in microglia.

CCL7 CCL8

6.59e-054116233160071
Pubmed

Inactivation of RASSF1A, RARbeta2 and DAP-kinase by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma.

RARB DAPK2

6.59e-054116219221469
Pubmed

CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice.

CCL7 CCL8

6.59e-054116220234092
Pubmed

SHP2 mediates the localized activation of Fyn downstream of the α6β4 integrin to promote carcinoma invasion.

ITGA6 PTPN11

6.59e-054116220855525
Pubmed

Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice.

CCL7 CCL8

6.59e-054116223033370
Pubmed

Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer.

RARB TIMP3

6.59e-054116222694820
Pubmed

Chemokine expression by small sputum macrophages in COPD.

CCL7 CCL13

6.59e-054116221327296
Pubmed

Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients.

RARB DAPK2

6.59e-054116211839665
Pubmed

Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites.

CCL7 CCL8

6.59e-054116217364026
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

RARS1 TRIO CDKN2AIP RACGAP1 NUMB RPL3 VCL

6.64e-05298116730737378
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

GRM5 TNFRSF21 TUB SLC9A1 TTC7B PI4KA NUMB SVOP

6.71e-05405116838187761
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NSD2 WDR46 PSMC3 PRPF8 LONP1 SND1 MACF1 RPL3 VCL HDLBP

6.96e-056531161022586326
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RALGDS RNMT PPP2R2D NSD2 XPO4 ARHGAP11A PPP2R2A CCDC88A RACGAP1

7.35e-05529116914621295
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ANK3 TRIO ITGA6 CCDC88A TTC7B PI4KA NUMB MACF1

8.78e-05421116836976175
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

ATP6V1B2 RARS1 LONP1 RUVBL1 SND1 RPL3 HDLBP

8.84e-05312116737120454
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATP6V1B2 RARB ANK3 TRIO PRPF8 FMNL2 MIPOL1 FBH1 TTC7B RALBP1 SIPA1L1 FMN2 MACF1 UROD

9.95e-0512851161435914814
Pubmed

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.

CDKL2 WDR46 UBL5 DTWD2

1.01e-0472116424270810
Pubmed

Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.

ANK3 CTNNA3

1.10e-045116218163421
Pubmed

Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.

PPP2R2A PPP2R2B

1.10e-045116215578586
Pubmed

Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.

PPP2R2A PPP2R2B

1.10e-045116217529992
Pubmed

The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway.

PTPN11 RACGAP1

1.10e-045116216873377
Pubmed

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.

TTC7B PI4KA

1.10e-045116226571211
Pubmed

Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.

RARB TIMP3

1.10e-045116216858683
Pubmed

Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men.

RARB TIMP3

1.10e-045116220606036
InteractionRHOB interactions

ANK3 TRIO ITGA6 ARHGAP11A FMNL2 LONP1 SLC9A1 CCDC88A TTC7B RALBP1 PI4KA SIPA1L1 RACGAP1 FMN2 NUMB MACF1 RPL3 PLXNA1

1.11e-0684011418int:RHOB
InteractionC11orf52 interactions

ANK3 TRIO ITGA6 LONP1 CCDC88A PI4KA FMN2 NUMB MACF1 RPL3 PLXNA1

1.55e-0631111411int:C11orf52
InteractionRAB35 interactions

RHOD ANK3 TRIO ITGA6 FMNL2 SLC9A1 CCDC88A PI4KA FMN2 NUMB MACF1 RPL3 PLXNA1 GNPAT

4.42e-0657311414int:RAB35
InteractionRAC1 interactions

ANK3 TRIO ITGA6 FMNL2 OPHN1 LONP1 PPP2R2B SLC9A1 CCDC88A RALBP1 PI4KA RACGAP1 FMN2 NUMB MACF1 HABP2 RPL3 PLXNA1 HDLBP

7.72e-06106311419int:RAC1
InteractionLCK interactions

RARS1 ANK3 TRIO ETFA TUB SOCS2 PTPN11 CCDC88A PI4KA FMN2 NUMB MACF1

1.25e-0546311412int:LCK
InteractionCTNNB1 interactions

RARS1 RHOD ANK3 NSD2 PSMC3 FMNL2 SOCS2 PTPN11 CCDC88A RUVBL1 SND1 SIPA1L1 CTNNA3 NUMB ABCC12 RPL3 VCL HDLBP

1.42e-05100911418int:CTNNB1
InteractionPHLPP1 interactions

RARS1 RANBP3 CD2AP PRPF8 PPP2R2A CCDC88A RUVBL1 SND1 RPL3 HDLBP

1.97e-0533311410int:PHLPP1
InteractionKCNA3 interactions

RARS1 ANK3 CD2AP PSMA6 PTPN11 CCDC88A RUVBL1 SND1 SIPA1L1 CTNNA3 NUMB MACF1 TRPM1 RPL3 VCL HDLBP

3.15e-0587111416int:KCNA3
InteractionANKRD55 interactions

RARS1 ETFA PSMC3 PRPF8 PPP2R2A RUVBL1 PI4KA RPL3

4.67e-052281148int:ANKRD55
InteractionIER5 interactions

PPP2R2D PPP2R2A PPP2R2B

4.84e-05131143int:IER5
InteractionLYN interactions

ZNF577 RHOD ANK3 TRIO NSD2 PRPF8 FMNL2 CCDC88A PI4KA RACGAP1 FMN2 NUMB MACF1 PLXNA1

5.60e-0572011414int:LYN
InteractionSERTAD2 interactions

PPP2R2D PPP2R2A PPP2R2B CTNNA3

6.86e-05391144int:SERTAD2
InteractionMMP3 interactions

TIMP3 CCL7 CCL8 CCL13

6.86e-05391144int:MMP3
InteractionACKR4 interactions

CCL7 CCL8 CCL13

7.63e-05151143int:ACKR4
InteractionRAB2A interactions

ATP6V1B2 RHOD ETFA ITGA6 FMNL2 LONP1 SLC9A1 CCDC88A PI4KA FMN2 NUMB HDLBP

8.91e-0556711412int:RAB2A
InteractionRHOD interactions

RHOD ANK3 ITGA6 FMNL2 LONP1 SLC9A1 CCDC88A PI4KA FMN2 NUMB MACF1 PLXNA1

9.68e-0557211412int:RHOD
InteractionKCTD13 interactions

ATP6V1B2 ANK3 TRIO PSMA6 PSMC3 GRM5 FMNL2 OPHN1 PPP2R2A LONP1 TTC7B SND1 PI4KA SIPA1L1 OGDHL MACF1 SRPX RPL3 VCL HDLBP

1.00e-04139411420int:KCTD13
InteractionCDH1 interactions

RARS1 ANK3 CD2AP ITGA6 FMNL2 SLC9A1 RUVBL1 SND1 PI4KA CTNNA3 NUMB MACF1 VCL HDLBP

1.11e-0476811414int:CDH1
InteractionDIRAS3 interactions

ANK3 PSMC3 ITGA6 SLC9A1 CCDC88A FMN2 NUMB MACF1

1.23e-042621148int:DIRAS3
InteractionRHOA interactions

RHOD ANK3 TRIO ETFA ITGA6 ARHGAP11A FMNL2 OPHN1 LONP1 SLC9A1 PTPN11 CCDC88A PI4KA LPL FMN2 NUMB MACF1 PLXNA1

1.33e-04119911418int:RHOA
InteractionSFN interactions

RANBP3 CD2AP ARHGAP11A PRPF8 PPP2R2B CCDC88A SIPA1L1 RACGAP1 FMN2 NUMB MACF1 KIF13A VCL

1.48e-0469211413int:SFN
InteractionPPP4C interactions

PPP2R2D REL PPP2R2A PPP2R2B RALBP1 UBXN10

1.57e-041421146int:PPP4C
InteractionCTNNA1 interactions

RHOD ANK3 FMNL2 CCDC88A SIPA1L1 CTNNA3 NUMB MACF1 VCL

1.59e-043471149int:CTNNA1
InteractionSERTAD4 interactions

PPP2R2D PPP2R2A PPP2R2B

1.60e-04191143int:SERTAD4
InteractionCTDSPL interactions

ANK3 ITGA6 TTC7B FMN2 NUMB

1.76e-04921145int:CTDSPL
CytobandEnsembl 112 genes in cytogenetic band chr8p21

ATP6V1B2 PPP2R2A ADRA1A LPL

3.97e-041351164chr8p21
CytobandEnsembl 112 genes in cytogenetic band chr17q12

SLFN5 CCL7 CCL8 CCL13

5.76e-041491164chr17q12
Cytoband2q24.3

CERS6 XIRP2

7.42e-041611622q24.3
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2D PPP2R2A PPP2R2B

3.26e-0515773696
GeneFamilyChemokine ligands|Endogenous ligands

CCL7 CCL8 CCL13

9.27e-0445773483
GeneFamilyAAA ATPases

PSMC3 LONP1 RUVBL1

1.49e-0353773413
GeneFamilyDNA helicases

FBH1 RUVBL1

2.34e-03177721167
CoexpressionYAGI_AML_WITH_T_8_21_TRANSLOCATION

TRIO ARID4A CD2AP REL CERS6 CLSTN1 TNFRSF21 RALBP1 PI4KA CD34 SIPA1L1 MACF1

9.30e-0837211512M19261
CoexpressionGSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP

ANK3 PLAAT4 HPSE2 SND1 SIPA1L1 KIF13A SVOP MOBP

2.34e-061941158M6159
CoexpressionGSE2585_THYMIC_DC_VS_MTEC_DN

ATP6V1B2 RNMT PSMA6 REL TNFRSF21 TRPM1 CCL13 UROD

2.94e-062001158M6283
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

RALGDS ANK3 ARID4A CDKL2 VSTM2A CERS6 GRM5 ZNF462 CCDC88A CTNNA3 FMN2 OGDHL SVOP

1.32e-0570311513M39070
CoexpressionSAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN

IL12RB2 ARID4A GRM5 NUMB

1.86e-05361154M15473
CoexpressionPLASARI_TGFB1_TARGETS_10HR_DN

MRC1 RARB TSPY26P FMNL2 LPL CYP7B1 CCL8 GULP1

2.68e-052711158MM1075
CoexpressionGSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_UP

MRC1 PLAAT4 CREM MACF1 CCL7 CCL8 CCL13

2.87e-051991157M7652
CoexpressionHALLMARK_MITOTIC_SPINDLE

TRIO CD2AP OPHN1 CCDC88A RALBP1 RACGAP1 VCL

2.87e-051991157M5893
CoexpressionGSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP

WDR46 PRPF8 PPP2R2A LONP1 RUVBL1 RACGAP1 ILKAP

2.96e-052001157M4599
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_1_CELL

RARB RHOD ANK3 TRIO HPSE2 FMNL2 TNFRSF21 DNAH14

4.77e-052941158M45674
CoexpressionYAP1_DN

TSPY26P SLC9A1 TIMP3 MOBP

5.42e-05471154M2841
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP27 CLSTN1 TNFRSF21 LPL CCL7 CCL8 PLXNA1

2.96e-0716811674ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP27 CLSTN1 TNFRSF21 LPL CCL7 CCL8 PLXNA1

2.96e-07168116704e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP27 CLSTN1 TNFRSF21 LPL CCL7 CCL8 PLXNA1

3.08e-071691167454b92b9b67299a64278c010db033ca5b9d217a0
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ANK3 DAPK2 CERS6 XIRP2 LPL CTNNA3 VCL

5.67e-0718511676baccb26f999145e51b91d94315bf8d4655bef31
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF577 RARS1 ANK3 HPSE2 FMNL2 KIF13A GULP1

6.32e-0718811676468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF577 RARS1 ANK3 HPSE2 FMNL2 KIF13A GULP1

6.32e-0718811677a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF577 RARS1 ANK3 HPSE2 FMNL2 KIF13A GULP1

6.32e-0718811679cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

DAPK2 CERS6 ADRA1A XIRP2 LPL CTNNA3 RPL3L

6.54e-0718911675e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ANK3 CERS6 ADRA1A XIRP2 LPL CTNNA3 VCL

7.53e-071931167dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 CD2AP ITGA6 ATP8B1 TNFRSF21 PPP2R2B RALBP1

7.80e-0719411674579b4a44f7c731553a284843c296866027d7c0e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 CD2AP ITGA6 ATP8B1 TNFRSF21 PPP2R2B RALBP1

8.07e-0719511673d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellCOVID-19|World / Condition, Lineage and Cell class

PLAAT4 SLFN5 CREM MACF1 CCL7 CCL8 CCL13

8.64e-071971167228f641d79282cc3dc51b95a1f4b0cccfc200735
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ATP6V1B2 ARHGAP11A CCDC88A LPL RACGAP1

6.40e-06174116665147b0f8c2ccadd5685430d31081520c157536a
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ATP6V1B2 VSTM2A ARHGAP11A TNFRSF21 LPL

6.84e-061761166270d7908dbd84028958d257f94941dc685e20255
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIO MMP27 SLFN5 CCL7 CCL8 PLXNA1

7.77e-0618011666c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCellRV|World / Chamber and Cluster_Paper

DAPK2 ADRA1A XIRP2 LPL CTNNA3 RPL3L

8.02e-061811166bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ANK3 DAPK2 XIRP2 LPL CTNNA3 VCL

8.81e-061841166ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellE15.5-Epithelial-airway_epithelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RARB ANK3 DAPK2 TNFRSF21 STX19 PPP2R2B

9.37e-061861166bb2c7af3b1d8478c49a8626dbfd6c92c5e7adc4a
ToppCellE15.5-Epithelial-airway_epithelial_cell-club_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RARB ANK3 DAPK2 TNFRSF21 STX19 PPP2R2B

9.37e-06186116686c809b99088d3d6c8f87785797c4beefdcddbe7
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

DAPK2 CERS6 ADRA1A XIRP2 CTNNA3 RPL3L

9.66e-06187116678cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

DAPK2 CERS6 ADRA1A XIRP2 CTNNA3 RPL3L

9.96e-0618811660758b474457efa36488e0195f7357100f4b6a090
ToppCellCF-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

IL12RB2 PLAAT4 DAPK2 SLFN5 PCNX2 PPP2R2B

9.96e-06188116615057036b46c9df621ec4955aa94ca3036245d45
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

ANK3 DAPK2 CERS6 CTNNA3 RPL3L VCL

1.03e-0518911669c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell(011)_pDC|World / immune cells in Peripheral Blood (logTPM normalization)

DAPK2 CD2AP TNFRSF21 C5orf34 CCDC88A SRPX

1.09e-051911166d82ac4f6d9863734e09bf3cb71c1354a49b66b4f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 DAPK2 ITGA6 CERS6 ATP8B1 TNFRSF21

1.16e-051931166a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

ANK3 DAPK2 CERS6 ADRA1A LPL CTNNA3

1.23e-051951166f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RARB DAPK2 HPSE2 CERS6 TIMP3 VCL

1.23e-051951166803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ANK3 ITGA6 SLFN5 SOCS2 MACF1 RPL3

1.23e-0519511664bdedd924564a260841a9153604026b57487c83d
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

ANK3 DAPK2 ADRA1A XIRP2 LPL CTNNA3

1.23e-05195116675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RARB DAPK2 HPSE2 CERS6 TIMP3 VCL

1.23e-0519511664f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

MRC1 DAPK2 CD2AP ATP8B1 SLFN5 TIMP3

1.23e-0519511666b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

MRC1 RARB FMNL2 ZNF462 TIMP3 SRPX

1.26e-051961166e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

MRC1 ATP6V1B2 REL FMNL2 CCDC88A SIPA1L1

1.26e-0519611664929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ITGA6 CLSTN1 FMNL2 TIMP3 CD34 GULP1

1.30e-05197116666339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

ANK3 ARID4A CDKL2 GRM5 PPP2R2B SIPA1L1

1.30e-05197116679b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellCF-Myeloid-Monocyte_Macrophage|Myeloid / Disease state, Lineage and Cell class

TRIO CERS6 FMNL2 CCDC88A SND1 RPL3

1.30e-05197116677b150a987c0a8abe73920d93d69a590ebbbdfea
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

ANK3 ARID4A CDKL2 GRM5 PPP2R2B SIPA1L1

1.30e-051971166d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellT_cells-CTLs|World / Immune cells in Kidney/Urine in Lupus Nephritis

RALGDS PLAAT4 SLFN5 PPP2R2B MACF1 VCL

1.30e-0519711662de34e20915a247bee75aa40495e23c20bb23e18
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ANK3 HPSE2 DNAH14 SUGCT MACF1 CYP7B1

1.30e-051971166f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CD2AP ETFA SLFN5 CCDC88A RALBP1 HDLBP

1.34e-05198116676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLAAT4 SLFN5 CREM MACF1 CCL7 CCL8

1.34e-051981166454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

ARID4A ETFA PTPN11 CCDC88A TIMP3 RALBP1

1.38e-05199116619674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellCF-Myeloid-Monocyte_Macrophage|CF / Disease state, Lineage and Cell class

TRIO CERS6 FMNL2 CCDC88A SND1 RPL3

1.38e-051991166bf95eacb31a4a847350f9d6e95ca76c6b730c400
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

CD2AP ETFA CERS6 SLFN5 PTPN11 RALBP1

1.38e-051991166d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

ATP6V1B2 CLSTN1 GRM5 PCNX2 PI4KA SVOP

1.41e-052001166c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellParenchyma_COVID-19-Immune-TX-MoAM-3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

MRC1 ATP6V1B2 CCDC88A DNAJA4 LPL CCL7

1.41e-052001166a0eb6e9e21930539b8939082c4097f6dfe8efa9b
ToppCellBL-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MRC1 FMNL2 CCDC88A LPL CCL7 CCL8

1.41e-052001166dc3d5af1d4b15cc258d456f9f450550874456299
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LMNTD2 FMNL2 TNFRSF21 OPHN1 ZNF462

3.90e-051451165f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCellLPS-antiTNF-Endothelial-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF577 CDKN2AIP PCNX2 CYP7B1 CAPN5

5.87e-05158116550df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

IL12RB2 PLEKHD1 TNFRSF21 C5orf34 PLXNA1

6.05e-051591165ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 LPL CCL7 CCL8 PLXNA1

6.23e-0516011650544bc465af208da448858d6e174ff56f2e08a46
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

PLAAT4 VSTM2A GRM5 XIRP2 CCL8

7.01e-051641165362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP11A CCDC88A LPL RACGAP1 PLXNA1

7.21e-0516511651dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 RALGDS CCL7 CCL8 TRPM1

7.21e-0516511656dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF577 CDKN2AIP PCNX2 CYP7B1 CAPN5

7.42e-0516611653b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

TTC7B TIMP3 CD34 OGDHL CYP7B1

7.42e-0516611659788486582cc2c5f28b9ea015e235732f9fefb1e
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATP6V1B2 TRIO REL FMNL2 SIPA1L1

8.30e-051701165cc66ac6846c58be9493eb270644ee3ce0f86cfea
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SLFN5 LPL CCL8 PLXNA1

8.30e-051701165067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 LPL CCL7 CCL8 PLXNA1

8.77e-0517211657295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
ToppCelldroplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 OPHN1 CCL7 CCL8 TRPM1

9.01e-05173116531ea04e65876c42b90245d280f0b6439bfffbace
ToppCelldroplet-Lung-nan-21m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 OPHN1 CCL7 CCL8 TRPM1

9.01e-0517311651cff815536f620e32b9805666e1aa711462c2d25
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

MRC1 SLC9A1 CCDC88A CCL8 CCL13

9.26e-05174116575b3a852140fb726025c3c987143d67944afde2d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN1 PLEKHD1 PPP2R2B CAPN5 FGFBP1

9.26e-05174116546bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANK3 PPP2R2B CTNNA3 FMN2 GULP1

9.51e-051751165bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANK3 PPP2R2B CTNNA3 FMN2 GULP1

9.51e-0517511658b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANK3 PPP2R2B CTNNA3 FMN2 GULP1

9.51e-0517511650b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 ATP6V1B2 VSTM2A TNFRSF21 LPL

9.77e-051761165e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ATP6V1B2 RARS1 VSTM2A LPL

9.77e-051761165b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SLFN5 LPL CCL7 PLXNA1

1.00e-04177116526bad614560609d318bfc9c235a698bca4e1c22c
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ATP6V1B2 RARS1 VSTM2A LPL

1.00e-04177116567cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 ATP6V1B2 VSTM2A TNFRSF21 LPL

1.00e-04177116571919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CD2AP FMNL2 CCDC88A LPL

1.00e-04177116514fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IL12RB2 PLAAT4 SLFN5 CREM MACF1

1.09e-0418011650a98d21fec67a890e75ebf0e2d23adddd77da214
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 ARHGAP11A PLEKHD1 C5orf34 RACGAP1

1.09e-041801165401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IL12RB2 PLAAT4 SLFN5 CREM MACF1

1.09e-0418011651c8398342d3fa4d5ca9a8a63626cc497c5291446
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IL12RB2 PLAAT4 SLFN5 CREM MACF1

1.09e-041801165ddbab26b05f057bd78b78773381cd447bd2e2726
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRC1 ATP6V1B2 CCDC88A RACGAP1 TRPM1

1.11e-041811165a8d4b2340d99734bf9379b467fb481c598b9b4fb
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

ANK3 XIRP2 DNAJA4 LPL CTNNA3

1.14e-041821165287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD2AP REL SLFN5 CCDC88A MACF1

1.14e-041821165f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WWC3 CLSTN1 PLEKHD1 PPP2R2B CAPN5

1.17e-04183116583592c332b1e82673f993d37c7f480befdc3dcda
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 NSD2 VSTM2A ARHGAP11A LPL

1.17e-04183116542dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSTM2A MMP27 CCL8 SRPX GULP1

1.20e-041841165fea4fe648e9749177d0783443dc26a7df5807883
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRC1 ATP6V1B2 FMNL2 CCDC88A LPL

1.20e-041841165840fac463665ed18752f402f7d1ef2e5052bdf74
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD2AP REL SLFN5 CCDC88A MACF1

1.20e-0418411651154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ATP6V1B2 VSTM2A CCDC88A LPL

1.20e-0418411658e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSTM2A MMP27 CCL8 SRPX GULP1

1.20e-04184116596a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSTM2A MMP27 CCL8 SRPX GULP1

1.20e-041841165780eb72da43527f0c72effac3423ec7384f05f20
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADRA1A XIRP2 LPL CTNNA3 RPL3L

1.20e-041841165e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

CD2AP PLEKHD1 TNFRSF21 CCDC88A SRPX

1.20e-0418411652817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARB CD34 LPL CTNNA3 SRPX

1.20e-041841165fe4d3def3da4ffdea5ae6bb059f5397efd58fef3
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLFN5 CD34 LPL CCL8 SRPX

1.23e-0418511653cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLFN5 CD34 LPL CCL8 SRPX

1.23e-04185116500258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLFN5 CD34 LPL CCL8 SRPX

1.23e-041851165a94694e226856bc5b168464f52d76004145717a5
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD2AP REL SLFN5 CCDC88A MACF1

1.23e-0418511657adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 PPP2R2B LPL CTNNA3 GULP1

1.23e-041851165f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell5'-Adult-LargeIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 PPP2R2B LPL CTNNA3 GULP1

1.23e-041851165317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 PPP2R2B LPL CTNNA3 GULP1

1.23e-0418511657bb8fdfe04f85d25056380ec58222366de323a21
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac|normal_Pleural_Fluid / Location, Cell class and cell subclass

CD2AP LPL CCL7 KIF13A PLXNA1

1.27e-0418611653314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

MRC1 RALGDS ATP6V1B2 CCDC88A LPL

1.27e-04186116533d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

ATP8B1 PPP2R2B CD34 CCL7 SRPX

1.27e-041861165e93415b59dd89bc8a966dab0e0b65fe215933598
ComputationalHeparin binding.

LPL CCL7 CCL8 FGFBP1

5.08e-0528804MODULE_385
DrugAmiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

RARB CCDC88A TIMP3 DNAJA4 OGDHL HABP2 MOBP FGFBP1

7.31e-0619711583339_UP
DrugMK-886; Down 200; 1uM; MCF7; HG-U133A

PLAAT4 TNFRSF21 CREM ADRA1A TIMP3 SIPA1L1 LPL MACF1

7.87e-061991158264_DN
Drug(1)-Nipecotic acid [498-95-3]; Up 200; 31uM; HL60; HT_HG-U133A

KRT85 PPP2R2B ADRA1A DNAJA4 CCL7 MOBP PLXNA1 VCL

7.87e-0619911583121_UP
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2D PPP2R2A PPP2R2B

1.20e-05121143DOID:1441 (implicated_via_orthology)
Diseaselevel of corneodesmosin in blood serum

CCL8 CCL13

1.48e-0521142OBA_2040974
DiseaseC-C motif chemokine 8 measurement

CCL8 CCL13

4.43e-0531142EFO_0008055
DiseaseC-C motif chemokine 7 measurement

CCL7 CCL8 CCL13

1.91e-04291143EFO_0008054
Diseasecardiac troponin T measurement

RARB TRIO SUGCT CTNNA3 KIF13A VCL

2.14e-042191146EFO_0005043
DiseaseShwachman-Diamond syndrome (implicated_via_orthology)

SBDS RPL3

3.07e-0471142DOID:0060479 (implicated_via_orthology)
Diseasefactor VIII measurement

RALGDS ABCC12 RPL3

5.00e-04401143EFO_0004630
Diseasecorneodesmosin measurement

CCL8 CCL13

5.23e-0491142EFO_0801499
Diseasecardiac troponin I measurement

TNFRSF21 PCNX2 CTNNA3 HABP2 VCL

6.20e-041761145EFO_0010071
DiseaseX-12063 measurement

XPO4 DNAH14 SUGCT RACGAP1 TENT2

7.95e-041861145EFO_0021283
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

PI4KAP2 PI4KA

1.31e-03141142DOID:0060413 (implicated_via_orthology)
Diseaseunipolar depression, anxiety

CDKN2AIP CCDC88A

1.31e-03141142EFO_0003761, EFO_0005230
Disease3-hydroxyanthranilic acid measurement

TNFRSF21 PCNX2

1.50e-03151142EFO_0010447
Diseasecoronary artery calcification

ANK3 GRM5 SOCS2 ZNF462 SIPA1L1 LPL NUMB

1.86e-034501147EFO_0004723
Diseasenon-lobar intracerebral hemorrhage

RARB CDKN2AIP DNAH14

1.88e-03631143EFO_0010178
Diseasesporadic amyotrophic lateral sclerosis

ANK3 ABCC12 MOBP PLXNA1

2.16e-031401144EFO_0001357
Diseasemigraine disorder, systolic blood pressure

HPSE2 SUGCT

2.17e-03181142EFO_0006335, MONDO_0005277
DiseaseDermatitis, Allergic Contact

MRC1 CREM SOCS2

2.25e-03671143C0162820
Diseasepuberty, height growth measurement

DNAJC27 SOCS2

2.42e-03191142EFO_0001382, EFO_0005201
Diseasemigraine disorder

CDKN2AIP HPSE2 ZNF462 SUGCT CTNNA3 MACF1

2.68e-033571146MONDO_0005277
DiseaseX-24309 measurement

ADRA1A NUMB

2.69e-03201142EFO_0800872
DiseaseTesticular Germ Cell Tumor

CDKL2 CLSTN1 SUGCT

2.87e-03731143EFO_1000566
DiseaseLeft Ventricle Remodeling

ADRA1A SLC9A1

2.96e-03211142C0600520
DiseaseVentricular Remodeling

ADRA1A SLC9A1

2.96e-03211142C0600519
DiseaseMalignant neoplasm of breast

RARB NSD2 PHF7 ATP8B1 ARHGAP11A PLEKHD1 C5orf34 ADRA1A SIPA1L1 MACF1 HDLBP

2.99e-03107411411C0006142
DiseaseLiver carcinoma

ETFA ARHGAP11A SOCS2 ADRA1A CD34 RACGAP1 SRPX

3.60e-035071147C2239176
DiseaseCancer of Head

RARB UROD

3.86e-03241142C0751177
DiseaseHead Neoplasms

RARB UROD

3.86e-03241142C0018675
DiseaseUpper Aerodigestive Tract Neoplasms

RARB UROD

3.86e-03241142C0887900

Protein segments in the cluster

PeptideGeneStartEntry
KGVKIIKELAAVCDV

SUGCT

121

Q9HAC7
VVRKAYGKCVIVVKE

C21orf140

111

B9A014
RKVCVGGKRRKDEIS

PPP2R2B

391

Q00005
GSKLTCEKIVKERYE

CFAP43

1611

Q8NDM7
RGAFCEAKIKTVKRL

ARID4A

21

P29374
KVCASGKRKKDEISV

PPP2R2A

396

P63151
KAVIFRTKLGKEICA

CCL13

61

Q99616
REKKAAKTLGIVVGC

ADRA1A

266

P35348
KTAVKTRVCRKDFPE

FGFBP1

131

Q14512
RKVCTGGKRRKDEIS

PPP2R2D

401

Q66LE6
RAKVPIVKFRDKVSC

TENT2

261

Q6PIY7
IIKCEGDKVRSAVQK

CAPN5

541

O15484
SCSGAKVIREKKIIE

DNAJA4

196

Q8WW22
KTDTEGKIKAKEYCR

CD2AP

261

Q9Y5K6
DCGKKRATEDVLVKI

CLSTN1

241

O94985
DKCKVKIGRRFSEER

DTWD2

121

Q8NBA8
RTCEVIKDGRFKVAK

ATP8B1

176

O43520
YTKATARKCLLEKVE

RANBP3

376

Q9H6Z4
KCEGIYRVSGIKSKV

RALBP1

226

Q15311
LATKCIIKIVEFAKR

RARB

231

P10826
RKCINIIETKGIKTE

OPHN1

391

O60890
VAPKKARECVGKTVT

UROD

286

P06132
GRVKKIDAAVCDKTT

MMP27

371

Q9H306
EKGQIKVIRKGEVSC

GRM5

516

P41594
GAIIVDRIYKTKECK

MIPOL1

241

Q8TD10
VVLKKDVDCAYLRKS

KRT85

226

P78386
EVGKSCIIKRYCEKR

DNAJC27

26

Q9NZQ0
IKAKIDACKRGDVTV

IL12RB2

21

Q99665
VVKICKRKYRGSEIE

CDKN2AIP

541

Q9NXV6
KEIGIYKESCVRLKE

CCDC88A

871

Q3V6T2
SFKVIKVNKECVRGL

PCNX2

1771

A6NKB5
KEKIKERIQSCYRGE

PLXNA1

366

Q9UIW2
IRVKAGETQKKVIFC

LPL

431

P06858
RICEEAYGRSKDKKI

OGDHL

551

Q9ULD0
KKSERGVTAKKEYVC

NSD2

656

O96028
VKGQSVTLIVDCKKR

COL11A2

156

P13942
KFKVKRCGVSELEKE

PI4KA

1806

P42356
KEKTIAAKRAGVTCI

LONP1

896

P36776
GLKIVAVSCREKFVR

LMNTD2

361

Q8IXW0
YLVKVESKGLEKVTC

ITGA6

906

P23229
TTKEVERGKSKCVKY

PTPN11

356

Q06124
IVRSDVALDKQKGCK

HPSE2

151

Q8WWQ2
ELVKKCKIDIESGQR

MACF1

2636

Q9UPN3
VVGCKTDLRKDKSLV

RHOD

126

O00212
CRNKDTGRIVAIKKF

CDKL2

21

Q92772
ETCAAVRRGSAKKKI

CTNNA3

866

Q9UI47
CGKTEIAERKIKRIY

HABP2

301

Q14520
VGATILDVCKRVRKK

FBH1

711

Q8NFZ0
ALAACVRLGVVEKKK

GNPAT

631

O15228
IVKKCREKSTGLEYA

DAPK2

36

Q9UIK4
KGTEVVRDAVRKLKF

GULP1

41

Q9UBP9
PKGDVISVEKTVKRC

ILKAP

176

Q9H0C8
KEAVIFKTKRGKEVC

CCL8

61

P80075
ELGKKRICRIITKDF

ANK3

1116

Q12955
LIVKIACKAVSRGKV

CERS6

321

Q6ZMG9
LRKAGKTADEICKAI

FMNL2

706

Q96PY5
ASKISERKGKVDICV

DNAH14

1461

Q0VDD8
CKVRTVKAGTLEKLV

RALGDS

111

Q12967
KKGRINKLVCTDIAD

RNMT

216

O43148
GNVKSIREKIIKCFS

CYP7B1

236

O75881
REAVIFKTKLDKEIC

CCL7

61

P80098
DKLVEKTGKICIRGN

C5orf34

171

Q96MH7
RKKEYVKCLESRVAV

CREM

306

Q03060
ERVKEAEEVCRQKKG

FMN2

1686

Q9NZ56
CFREIDELIKKETKG

SBDS

216

Q9Y3A5
IKAEIKCSGIREVKL

CD34

171

P28906
SISIIGKKRKRCVVF

METTL4

126

Q8N3J2
LERKQKREKECGVTA

NUMB

166

P49757
KKIQRDALTTCRKEG

MRC1

381

P22897
VKKLTCRVKIKEATG

KIF13A

866

Q9H1H9
YCVEKDRQTGKILKV

RARS1

616

P54136
ICRQAGLVKKSKDVV

ATP6V1B2

206

P21281
RSKRIAGKKVCRVES

ARHGAP11A

401

Q6P4F7
DVCGISSRKKAVEAK

SVOP

346

Q8N4V2
VRKKGTETEDVRCKQ

TNFRSF21

156

O75509
IKKEAARASRKICFV

PHF7

86

Q9BWX1
CVVGTKKRVLTLRKS

RPL3

336

P39023
CIAGTKKRVITLRKS

RPL3L

336

Q92901
TVKCDEKVKVFSVRG

ETFA

156

P13804
RCKQVEKAKVEVGVA

PLAAT4

126

Q9UL19
DGKFRLDSIICVKSK

SOCS2

101

O14508
KEIVKRLQFVSKGCE

SIPA1L1

936

O43166
LRKKLIGKEVCFTIE

SND1

86

Q7KZF4
RTEVAELRKEVGKCK

TEF

276

Q10587
ELRKEVGKCKTIVSK

TEF

281

Q10587
KKEIVDRKYSICKSG

MOBP

36

Q13875
ENKGTCKFRVKVRVK

SRPX

246

P78539
LAKFKVKRCGVSELE

PI4KAP2

271

A4QPH2
VFEECIKKTLRGKTV

ABCC12

641

Q96J65
ISGCDRTVKELKEKF

RACGAP1

386

Q9H0H5
IRRGATVDKTVCKKN

PRPF8

761

Q6P2Q9
EQTRDIVKGDVKTCK

XIRP2

906

A4UGR9
AVRGKDCAVIVTQKK

PSMA6

41

P60900
KVRKKDEGLYECRVT

VSTM2A

116

Q8TAG5
VIVKRGSLDKSIDCK

XPO4

121

Q9C0E2
LTARCLKGVEQEKKE

PLEKHD1

221

A6NEE1
KCKTFILRQLEVAGK

STX19

161

Q8N4C7
IDLDSQRKGKCAVIK

PSMC3

111

P17980
GKKVRVKCNTDDTIG

UBL5

11

Q9BZL1
IKRDKTLTGVKYHRC

ZNF577

121

Q9BSK1
FDEAEVRKIIRVCKG

VCL

126

P18206
KYVKKCLIAGERSKE

SLC9A1

556

P19634
GIRCVKKKEVKEAII

REL

106

Q04864
VEVVQKFCRIDKSRK

WDR46

106

O15213
REACGVIVELIKSKK

RUVBL1

46

Q9Y265
GVRKKTCSFRIKEEK

TRPM1

1296

Q7Z4N2
GKSARAVKVLKECIR

TTC7B

411

Q86TV6
KVILRTYKKCGRENL

ZNF98

106

A6NK75
EVPKIKERKVVGYKC

ZNF462

1956

Q96JM2
RACAVERKFIVRTKK

UBXN10

166

Q96LJ8
IIISGRKEKCEAAKE

HDLBP

951

Q00341
KVIVKEYECRASGRV

TSPY26P

251

Q9H489
QGITIKCRITRDKKG

TUB

261

P50607
KGALRGYVCAIKVEK

SLFN5

286

Q08AF3
RTIKKAICTGEKERR

WWC3

151

Q9ULE0
EIKKCVTAVDKRYRD

TRIO

1216

O75962
RFSVVKKCDQKGTKR

TRIO

2806

O75962
CNSDIVIRAKVVGKK

TIMP3

36

P35625