Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	polyamine transmembrane transporter activity	ATP13A2 SLC22A1 SLC22A3 SLC22A2 SLC47A1	1.92e-07	11	271	5	GO:0015203
GeneOntologyMolecularFunction	putrescine transmembrane transporter activity	SLC22A1 SLC22A2 SLC47A1	9.79e-06	4	271	3	GO:0015489
GeneOntologyMolecularFunction	spermidine transmembrane transporter activity	SLC22A1 SLC22A3 SLC22A2	2.42e-05	5	271	3	GO:0015606
GeneOntologyMolecularFunction	thiamine transmembrane transporter activity	SLC22A1 SLC22A2 SLC47A1	8.31e-05	7	271	3	GO:0015234
GeneOntologyMolecularFunction	small GTPase binding	LZTR1 TBC1D7 RPTOR DIAPH2 NGFR KPNB1 TNPO1 DMXL2 TNPO2 RANBP3 RAPGEF4 MICALL2 SYTL4 IPO11	1.34e-04	321	271	14	GO:0031267
GeneOntologyMolecularFunction	nuclear import signal receptor activity	KPNB1 TNPO1 TNPO2 IPO11	1.35e-04	20	271	4	GO:0061608
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	TMEM94 TCIRG1 ABCC8 ATP13A1 ATP13A2 ATP6V0A2	1.92e-04	62	271	6	GO:0019829
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ALOX12 ALOX5 ADO RPE65	3.35e-04	25	271	4	GO:0016702
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	ALOX12 ALOX5 ADO RPE65	3.92e-04	26	271	4	GO:0016701
GeneOntologyMolecularFunction	GTPase binding	LZTR1 TBC1D7 RPTOR DIAPH2 NGFR KPNB1 TNPO1 DMXL2 TNPO2 RANBP3 RAPGEF4 MICALL2 SYTL4 IPO11	4.32e-04	360	271	14	GO:0051020
GeneOntologyMolecularFunction	toxin transmembrane transporter activity	SLC22A1 SLC22A3 SLC22A2	4.97e-04	12	271	3	GO:0019534
GeneOntologyMolecularFunction	monoamine transmembrane transporter activity	SLC22A1 SLC22A3 SLC22A2	4.97e-04	12	271	3	GO:0008504
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	TMEM94 TCIRG1 ABCC8 ATP13A1 ATP13A2 ABCC6 ATP6V0A2	7.20e-04	109	271	7	GO:0042626
GeneOntologyMolecularFunction	azole transmembrane transporter activity	SLC22A1 SLC22A2 SLC47A1	8.05e-04	14	271	3	GO:1901474
GeneOntologyMolecularFunction	nucleocytoplasmic carrier activity	KPNB1 TNPO1 TNPO2 IPO11	8.85e-04	32	271	4	GO:0140142
GeneOntologyMolecularFunction	quaternary ammonium group transmembrane transporter activity	SLC22A1 SLC22A3 SLC22A2	9.97e-04	15	271	3	GO:0015651
GeneOntologyMolecularFunction	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	CHPF2 CHPF	1.08e-03	4	271	2	GO:0050510
GeneOntologyMolecularFunction	dopamine:sodium symporter activity	SLC22A1 SLC22A3	1.08e-03	4	271	2	GO:0005330
GeneOntologyMolecularFunction	arachidonate 12(S)-lipoxygenase activity	ALOX12 ALOX5	1.08e-03	4	271	2	GO:0004052
GeneOntologyMolecularFunction	acetate ester transmembrane transporter activity	SLC22A1 SLC22A2	1.08e-03	4	271	2	GO:1901375
GeneOntologyMolecularFunction	acetylcholine transmembrane transporter activity	SLC22A1 SLC22A2	1.08e-03	4	271	2	GO:0005277
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC6 SLC22A1 SLC22A2 SLC47A1	1.12e-03	34	271	4	GO:0042910
GeneOntologyMolecularFunction	carbon-sulfur lyase activity	CENPVL2 CENPVL1 CENPVL3	1.21e-03	16	271	3	GO:0016846
GeneOntologyBiologicalProcess	polyamine transport	ATP13A2 AZIN1 SLC22A1 SLC22A3 SLC22A2 SLC47A1	5.11e-08	17	269	6	GO:0015846
GeneOntologyBiologicalProcess	polyamine transmembrane transport	ATP13A2 AZIN1 SLC22A1 SLC22A3 SLC22A2	6.61e-07	14	269	5	GO:1902047
GeneOntologyBiologicalProcess	spermidine transmembrane transport	SLC22A1 SLC22A3 SLC22A2	8.69e-06	4	269	3	GO:1903711
GeneOntologyBiologicalProcess	putrescine transport	SLC22A1 SLC22A2 SLC47A1	8.69e-06	4	269	3	GO:0015847
GeneOntologyBiologicalProcess	spermidine transport	SLC22A1 SLC22A3 SLC22A2	4.26e-05	6	269	3	GO:0015848
Domain	WD40_repeat_dom	VPS11 TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B ARHGEF10L CSTF1 IFT122 TBL2	7.94e-08	297	272	19	IPR017986
Domain	WD40	TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B CSTF1 IFT122 TBL2	4.39e-07	268	272	17	SM00320
Domain	-	VPS11 TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B ARHGEF10L CSTF1 IFT122 TBL2	4.66e-07	333	272	19	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	VPS11 TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B ARHGEF10L CSTF1 IFT122 TBL2	5.11e-07	335	272	19	IPR015943
Domain	WD40_repeat	TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B CSTF1 IFT122 TBL2	5.40e-07	272	272	17	IPR001680
Domain	WD_REPEATS_1	TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B CSTF1 IFT122 TBL2	7.32e-07	278	272	17	PS00678
Domain	WD_REPEATS_2	TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B CSTF1 IFT122 TBL2	7.69e-07	279	272	17	PS50082
Domain	WD_REPEATS_REGION	TBL1Y BCAS3 CORO2B NWD2 RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B CSTF1 IFT122 TBL2	7.69e-07	279	272	17	PS50294
Domain	WD40	TBL1Y BCAS3 CORO2B RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B CSTF1 IFT122 TBL2	1.37e-06	259	272	16	PF00400
Domain	WD40_repeat_CS	TBL1Y CORO2B NWD2 WDR77 PHIP COP1 GEMIN5 SEC31B TBL1XR1 CSTF1 TBL2	2.94e-05	164	272	11	IPR019775
Domain	IMPORTIN_B_NT	KPNB1 TNPO1 TNPO2 IPO11	3.93e-05	14	272	4	PS50166
Domain	IBN_N	KPNB1 TNPO1 TNPO2 IPO11	5.29e-05	15	272	4	PF03810
Domain	IBN_N	KPNB1 TNPO1 TNPO2 IPO11	6.98e-05	16	272	4	SM00913
Domain	Importin-beta_N	KPNB1 TNPO1 TNPO2 IPO11	9.02e-05	17	272	4	IPR001494
Domain	HEMATOPO_REC_S_F1	CSF2RB IL21R IL9R	1.62e-04	8	272	3	PS01355
Domain	HEAT	RPTOR BRAT1 KPNB1 TNPO1 TNPO2 IPO11	1.94e-04	58	272	6	IPR000357
Domain	Hempt_rcpt_S_F1_CS	CSF2RB IL21R IL9R	2.40e-04	9	272	3	IPR003531
Domain	Orgcat_transp/SVOP	SLC22A1 SLC22A3 SLC22A2	2.40e-04	9	272	3	IPR004749
Domain	Spy1	SPDYE2B SPDYE2 SPDYE6	4.62e-04	11	272	3	PF11357
Domain	Speedy	SPDYE2B SPDYE2 SPDYE6	4.62e-04	11	272	3	IPR020984
Domain	ARM-type_fold	VPS11 NF1 RPTOR NBEAL2 DIAPH2 RIPOR1 BRAT1 KPNB1 TNPO1 BZW2 TNPO2 THADA LTN1 IPO11	4.76e-04	339	272	14	IPR016024
Domain	HEAT	RPTOR BRAT1 KPNB1 TNPO1 TNPO2	6.48e-04	48	272	5	PF02985
Pathway	REACTOME_ABACAVIR_TRANSMEMBRANE_TRANSPORT	SLC22A1 SLC22A3 SLC22A2	2.48e-05	5	193	3	M27147
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LZTR1 KIF26A TMEM94 BCAS3 C19orf47 APBB3 CBLC ANKLE1 ZFPM1 RPTOR NBEAL2 MCM3AP CCDC3 DIAPH2 RIPOR1 CHPF BRAT1 ALOX5 CREB3 CRYBG2 KIAA0930 ATP13A1 GEMIN5 ATP13A2 GBA2 ARHGEF10L GRAMD2A CELSR1 THADA ARHGEF40 IGF2R CELSR3 MAP1S ZNF500 ZFYVE26	6.69e-12	1105	281	35	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	LZTR1 TSPYL2 HLCS CHEK1 PASK PELO RPTOR MCM3AP CHPF2 TSR3 PHIP WWC1 GPBAR1 HDAC6 POLD1 ANGEL1 OBSL1 ECT2L ZKSCAN2 PARS2 KIF7 RSBN1 THADA ARHGEF40 RNH1 IL21R SUPT16H LTN1 LRP2 SMARCB1 UNC80 NIN	6.86e-10	1116	281	32	31753913
Pubmed	Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.	IGF2R SLC22A1 SLC22A3 SLC22A2	2.85e-07	8	281	4	11562346
Pubmed	Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements.	IGF2R SLC22A1 SLC22A3 SLC22A2	2.85e-07	8	281	4	16204191
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	IL12B ERCC1 HMGCR CHEK1 ZFPM1 PARP4 ALOX12 ALOX5 POLD1 RET LCAT IGF2R TLR2 CSTF1 CXCL8 IL9R	4.05e-07	421	281	16	19692168
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	IL12B ERCC1 HMGCR CHEK1 ZFPM1 PARP4 ALOX12 ALOX5 POLD1 RET LCAT IGF2R TLR2 CSTF1 CXCL8	4.77e-07	374	281	15	19625176
Pubmed	Tissue-specific regulation of Igf2r/Airn imprinting during gastrulation.	IGF2R SLC22A1 SLC22A3 SLC22A2	5.09e-07	9	281	4	25918552
Pubmed	Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3).	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	16141367
Pubmed	Inhibition of human organic cation transporters by the alkaloids matrine and oxymatrine.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	24291757
Pubmed	Interaction of antidepressant and antipsychotic drugs with the human organic cation transporters hOCT1, hOCT2 and hOCT3.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	22806583
Pubmed	Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	17460754
Pubmed	Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families.	SLC22A1 SLC22A2 SLC47A1	5.22e-07	3	281	3	33375004
Pubmed	Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	15817714
Pubmed	OCT2 and MATE1 provide bidirectional agmatine transport.	SLC22A1 SLC22A2 SLC47A1	5.22e-07	3	281	3	21128598
Pubmed	Association of the SLC22A1, SLC22A2, and SLC22A3 genes encoding organic cation transporters with diabetic nephropathy and hypertension.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	20429798
Pubmed	Organic cation transporters modulate the uptake and cytotoxicity of picoplatin, a third-generation platinum analogue.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	20371711
Pubmed	Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients.	SLC22A1 SLC22A2 SLC47A1	5.22e-07	3	281	3	22735389
Pubmed	Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	19141712
Pubmed	Two unrelated children with overlapping 6q25.3 deletions, motor speech disorders, and language delays.	IGF2R SLC22A3 SLC22A2	5.22e-07	3	281	3	28767196
Pubmed	Functional characterization of the organic cation transporters (OCTs) in human airway pulmonary epithelial cells.	SLC22A1 SLC22A3 SLC22A2	5.22e-07	3	281	3	25883089
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	IL12B ERCC1 HMGCR CHEK1 ZFPM1 PARP4 ALOX12 ALOX5 POLD1 RET LCAT IGF2R TLR2 CSTF1 CXCL8	6.02e-07	381	281	15	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	IL12B ERCC1 HMGCR CHEK1 ZFPM1 PARP4 ALOX12 ALOX5 POLD1 RET LCAT IGF2R TLR2 CSTF1 CXCL8	6.22e-07	382	281	15	19170196
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TMEM214 EMC8 USP19 DIPK2A PELO GLB1 RPTOR CHPF2 CHPF BRAT1 WNK3 KPNB1 TNPO1 BZW2 ATP13A1 CAPN2 OBSL1 THADA ARHGEF40 IGF2R SLC47A1 LSS TBL2 IPO11	8.70e-07	942	281	24	31073040
Pubmed	Selective Response to Bacterial Infection by Regulating Siglec-E Expression.	MYD88 SIGLEC9 FOXP3 TLR2	1.32e-06	11	281	4	32889432
Pubmed	The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota.	MYD88 FOXP3 TLR2	2.07e-06	4	281	3	21512004
Pubmed	The organic cation transporters (OCT1, OCT2, EMT) and the plasma membrane monoamine transporter (PMAT) show differential distribution and cyclic expression pattern in human endometrium and early pregnancy decidua.	SLC22A1 SLC22A3 SLC22A2	2.07e-06	4	281	3	17393420
Pubmed	Foxp3-independent mechanism by which TGF-β controls peripheral T cell tolerance.	FOXP3 TGFBR2 CSF2RB	2.07e-06	4	281	3	28827353
Pubmed	Toll-like receptor 2 regulates intestinal inflammation by controlling integrity of the enteric nervous system.	MYD88 RET TLR2	2.07e-06	4	281	3	23994200
Pubmed	Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation.	VPS33B RPTOR FOXP3	2.07e-06	4	281	3	35705052
Pubmed	Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air.	IGF2R SLC22A3 SLC22A2	2.07e-06	4	281	3	12853484
Pubmed	Sepsis-induced expansion of granulocytic myeloid-derived suppressor cells promotes tumour growth through Toll-like receptor 4.	MYD88 FOXP3 TLR2	2.07e-06	4	281	3	27178223
Pubmed	Mycobacterium bovis bacille Calmette Guerin infection of human neutrophils induces CXCL8 secretion by MyD88-dependent TLR2 and TLR4 activation.	MYD88 TLR2 CXCL8	2.07e-06	4	281	3	15760459
Pubmed	Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.	KPNB1 TNPO1 TNPO2	2.07e-06	4	281	3	15037768
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	STARD8 SPTBN2 NEK9 LCMT2 PARP4 DMXL2 KIAA0930 THSD7A ZNF473 ATP13A1 PPFIBP1 COL27A1 GBA2 THADA LTN1 UNC80	3.15e-06	493	281	16	15368895
Pubmed	Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant t(w73) to 200 kb.	IGF2R SLC22A1 SLC22A3 SLC22A2	3.92e-06	14	281	4	11641723
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	TBC1D7 HMGCR USP19 DIPK2A CORO2B NF1 PELO MCM3AP ALOX12 ASNSD1 TNPO1 AEN ATP13A1 RANBP3 COP1 SPG11 AZIN1 RLF SLC44A1 ADO RNH1 TRMT44 CLEC14A SUPT16H GIGYF2 LSS SMPD1 ATP6V0A2	4.12e-06	1327	281	28	32694731
Pubmed	Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27.	SLC22A1 SLC22A3 SLC22A2	5.16e-06	5	281	3	9933568
Pubmed	Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.	ALOX12 ALOX5 CSF2RB	5.16e-06	5	281	3	36599368
Pubmed	OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.	SLC22A1 SLC22A2 SLC47A1	5.16e-06	5	281	3	24961373
Pubmed	Renal tumours in a Tsc1+/- mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin.	SLC22A1 SLC22A3 SLC22A2	5.16e-06	5	281	3	23228442
Pubmed	NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity.	MYD88 IL12B STAT2	5.16e-06	5	281	3	21383239
Pubmed	Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways.	MYD88 IL12B TLR2	5.16e-06	5	281	3	17289654
Pubmed	The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin.	IGF2R SLC22A3 SLC22A2	5.16e-06	5	281	3	18988810
Pubmed	MyD88 associated ROS generation is crucial for Lactobacillus induced IL-12 production in macrophage.	MYD88 IL12B TLR2	5.16e-06	5	281	3	22536449
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ERCC1 VPS45 SPTBN2 TSPYL2 APBB3 HLCS CORO2B CHPF UTRN KPNB1 DMXL2 HDAC6 ZNF473 ATP13A1 TNPO2 PPFIBP1 PLA2G3 RAPGEF4 OBSL1 SEC31B CELSR3 MAP1S ZNF197 LRP2 IFT122 DKK3 ZNF662	6.66e-06	1285	281	27	35914814
Pubmed	Integral and associated lysosomal membrane proteins.	VPS11 TCIRG1 RPTOR SPG11 ATP13A2 LRP2 ZFYVE26 ATP6V0A2	9.06e-06	126	281	8	17897319
Pubmed	The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells.	MYD88 IL21R IL9R	1.03e-05	6	281	3	24973819
Pubmed	Activation of invariant NKT cells by the helminth parasite schistosoma mansoni.	MYD88 IL12B TLR2	1.03e-05	6	281	3	16456008
Pubmed	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.	CENPVL2 CENPVL1 CENPVL3	1.03e-05	6	281	3	27250503
Pubmed	Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.	KPNB1 TNPO1 IPO11	1.03e-05	6	281	3	21965294
Pubmed	Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases.	MYD88 FOXP3 TLR2	1.03e-05	6	281	3	34877502
Pubmed	Norepinephrine transporter (NET), serotonin transporter (SERT), vesicular monoamine transporter (VMAT2) and organic cation transporters (OCT1, 2 and EMT) in human placenta from pre-eclamptic and normotensive pregnancies.	SLC22A1 SLC22A3 SLC22A2	1.03e-05	6	281	3	15135235
Pubmed	The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss.	MYD88 IL12B TLR2	1.03e-05	6	281	3	21149611
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	TBC1D7 PARP4 RPTOR AGL BRAT1 WDR77 TNPO1 ISYNA1 HDAC6 POLD1 ANGEL1 OBSL1 MAP3K6 PARS2 KIF7 MAP1S IPO11	1.06e-05	606	281	17	36538041
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	VPS11 TMEM214 TYSND1 NEK9 DIPK2A CHPF2 CHPF BRAT1 BZW2 ATP13A1 TNPO2 PPFIBP1 PUSL1 IGF2R RNH1 LTN1 GIGYF2 IPO11 NIN	1.44e-05	754	281	19	33060197
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	SPTBN2 PRPF6 NBEAL2 DIAPH2 ADGRF3 POLD1 RAPGEF4 SPG11 LOXHD1 MAP1S SLC4A1AP SMARCB1 GIGYF2 TBL2 IPO11	1.51e-05	497	281	15	36774506
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	TMEM214 PRPF6 VPS33B RPTOR KPNB1 TNPO1 BZW2 TNPO2 RANBP3 CAPN2 TBL1XR1 MAP1S LTN1 LSS TBL2 IPO11	1.54e-05	560	281	16	35241646
Pubmed	Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice.	MYD88 IL12B TLR2	1.78e-05	7	281	3	12244183
Pubmed	Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis.	FOXP3 TGFBR2 IL21R	1.78e-05	7	281	3	23569233
Pubmed	Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.	MYD88 TLR8 TLR2	1.78e-05	7	281	3	14976262
Pubmed	cGAS-STING and MyD88 Pathways Synergize in Ly6Chi Monocyte to Promote Streptococcus pneumoniae-Induced Late-Stage Lung IFNγ Production.	MYD88 IL12B TLR2	1.78e-05	7	281	3	34512626
Pubmed	Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.	MYD88 IL12B TLR2	1.78e-05	7	281	3	11698470
Pubmed	Cutting edge: Overlapping functions of TLR7 and TLR9 for innate defense against a herpesvirus infection.	MYD88 IL12B TLR2	1.78e-05	7	281	3	18424698
Pubmed	Sporadic Hirschsprung Disease: Mutational Spectrum and Novel Candidate Genes Revealed by Next-generation Sequencing.	LAMA1 AGL RET	1.78e-05	7	281	3	29093530
Pubmed	Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon.	MYD88 FOXP3 TLR2	1.78e-05	7	281	3	22693446
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	VPS11 VPS45 TCIRG1 TMEM214 HMGCR EMC8 NEK9 ZNF250 PASK NF1 MCM3AP UGCG KIAA0930 ATP13A1 SPG11 TGFBR2 THADA IGF2R LTN1 LSS TBL2 ATP6V0A2 IPO11	2.03e-05	1061	281	23	33845483
Pubmed	The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.	SLC22A1 SLC22A2 SLC47A1	2.84e-05	8	281	3	19536068
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SPTBN2 TMEM214 PRPF6 EMC8 LCMT2 PASK GLB1 NME7 TNPO1 DMXL2 ATP13A1 PPFIBP1 POLD1 RANBP3 OBSL1 SPG11 NR3C1 KIF7 THADA IGF2R SLC4A1AP SUPT16H LSS IFT122 DCXR TBL2 ATP6V0A2 NIN	3.25e-05	1487	281	28	33957083
Pubmed	FBXL12-Mediated Degradation of ALDH3 is Essential for Trophoblast Differentiation During Placental Development.	PCDH12 CAPN2 RNH1 SMPD1	3.27e-05	23	281	4	26124079
Pubmed	Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis.	MYD88 FOXP3 CSF2RB	4.23e-05	9	281	3	24625929
Pubmed	Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.	SPDYE2B SPDYE2 SPDYE6	4.23e-05	9	281	3	36272447
Pubmed	MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice.	MYD88 FOXP3 TLR2	4.23e-05	9	281	3	22466646
Pubmed	Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.	IL12B TLR8 NGFR ALOX5 FOXP3 NR3C1 TLR2 CXCL8 IL9R	4.62e-05	204	281	9	20503287
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.	IL12B TLR8 NGFR ALOX5 FOXP3 NR3C1 TLR2 CXCL8 IL9R	4.80e-05	205	281	9	19258923
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LAMA1 TMEM214 HMGCR EMC8 CD320 NEK9 USP19 DIPK2A NF1 GLB1 CHPF2 CHPF BZW2 H6PD CELSR1 THADA IGF2R CELSR3 TLL1 SLC22A3 LTN1 CNPY3 SMPD1 ATP6V0A2	4.88e-05	1201	281	24	35696571
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.	IL12B TLR8 NGFR ALOX5 FOXP3 NR3C1 TLR2 CXCL8 IL9R	5.17e-05	207	281	9	17703412
Pubmed	Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program.	ABCC8 ALOX5 SLC22A1 SLC22A2 SLC47A1	5.76e-05	51	281	5	20682687
Pubmed	Gene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood.	FOXP3 TGFBR2 TLR2	6.00e-05	10	281	3	20599261
Pubmed	Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation.	MYD88 STAT2 FOXP3	6.00e-05	10	281	3	24216477
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	SLC44A1 SLC22A1 SLC22A3 SLC22A2 LRP2	6.33e-05	52	281	5	26590417
Pubmed	Network organization of the human autophagy system.	TBC1D7 CHEK1 NEK9 RPTOR AGL UTRN TECPR1 OBSL1 MAP3K6 PARS2 MAP1S SUPT16H TBL2	6.46e-05	437	281	13	20562859
Pubmed	Hereditary spastic paraplegia with mental impairment and thin corpus callosum in Tunisia: SPG11, SPG15, and further genetic heterogeneity.	SPG11 ZFYVE26	6.50e-05	2	281	2	18332254
Pubmed	MyD88 is necessary for neutrophil recruitment in hypersensitivity pneumonitis.	MYD88 TLR2	6.50e-05	2	281	2	18285403
Pubmed	Properties and regulation of organic cation transport in freshly isolated human proximal tubules.	SLC22A1 SLC22A2	6.50e-05	2	281	2	11447227
Pubmed	Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model.	NR3C1 TBL1XR1	6.50e-05	2	281	2	24895125
Pubmed	The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma.	ALOX12 ALOX5	6.50e-05	2	281	2	30941737
Pubmed	Recurrent mutations of MYD88 and TBL1XR1 in primary central nervous system lymphomas.	MYD88 TBL1XR1	6.50e-05	2	281	2	22837180
Pubmed	Drug specificity and intestinal membrane localization of human organic cation transporters (OCT).	SLC22A1 SLC22A3	6.50e-05	2	281	2	16263091
Pubmed	Double-faced implication of CD4+ Foxp3+ regulatory T cells expanded by acute dengue infection via TLR2/MyD88 pathway.	MYD88 TLR2	6.50e-05	2	281	2	32125695
Pubmed	IL-12, but not IFN-alpha, promotes STAT4 activation and Th1 development in murine CD4+ T cells expressing a chimeric murine/human Stat2 gene.	IL12B STAT2	6.50e-05	2	281	2	15611252
Pubmed	Terminal deoxynucleotidyl transferase (TdT) expression is associated with FLT3-ITD mutations in Acute Myeloid Leukemia.	DNTT FLT3	6.50e-05	2	281	2	33091616
Pubmed	Cloning and characterization of two human polyspecific organic cation transporters.	SLC22A1 SLC22A2	6.50e-05	2	281	2	9260930
Pubmed	Effects of genetic polymorphisms on the OCT1 and OCT2-mediated uptake of ranitidine.	SLC22A1 SLC22A2	6.50e-05	2	281	2	29236753
Pubmed	Suppression by TFR cells leads to durable and selective inhibition of B cell effector function.	FOXP3 IL21R	6.50e-05	2	281	2	27695002
Pubmed	CD4⁺CD25⁺Foxp3⁺ regulatory T cells promote Th17 responses and genital tract inflammation upon intracellular Chlamydia muridarum infection.	MYD88 FOXP3	6.50e-05	2	281	2	23956419
Pubmed	Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4.	MYD88 TLR2	6.50e-05	2	281	2	16226506
Pubmed	Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88.	MYD88 TLR2	6.50e-05	2	281	2	15190057
Pubmed	MAP1S Protein Regulates the Phagocytosis of Bacteria and Toll-like Receptor (TLR) Signaling.	MYD88 MAP1S	6.50e-05	2	281	2	26565030
Pubmed	The R753Q polymorphism in Toll-like receptor 2 (TLR2) attenuates innate immune responses to mycobacteria and impairs MyD88 adapter recruitment to TLR2.	MYD88 TLR2	6.50e-05	2	281	2	28442574
Pubmed	Increased disease severity of parasite-infected TLR2-/- mice is correlated with decreased central nervous system inflammation and reduced numbers of cells with alternatively activated macrophage phenotypes in a murine model of neurocysticercosis.	MYD88 TLR2	6.50e-05	2	281	2	21482681
Interaction	TNFSF13B interactions	NF1 BRAT1 KPNB1 TNPO1 BZW2 TNPO2 PPFIBP1 GEMIN5 MAP3K6 IPO11	5.30e-06	119	274	10	int:TNFSF13B
Cytoband	Ensembl 112 genes in cytogenetic band chrXp11	TSPYL2 CENPVL2 CENPVL1 WNK3 FOXP3 HDAC6 KRBOX4 RGN CENPVL3 ZNF41	1.25e-04	377	281	10	chrXp11
Cytoband	2q35	CHPF GPBAR1 OBSL1 STK16 UNC80	1.29e-04	79	281	5	2q35
Cytoband	Xp11.22	CENPVL2 CENPVL1 WNK3 CENPVL3	3.42e-04	54	281	4	Xp11.22
Cytoband	13q12	ATP8A2 FLT3 GPR12	4.17e-04	24	281	3	13q12
GeneFamily	WD repeat domain containing	TBL1Y BCAS3 CORO2B RPTOR NBEAL2 WDR77 PHIP DMXL2 COP1 GEMIN5 SEC31B TBL1XR1 ARPC1B CSTF1 IFT122 TBL2	7.75e-09	262	179	16	362
GeneFamily	Armadillo repeat containing\|Importins	KPNB1 TNPO1 TNPO2 IPO11	2.55e-05	18	179	4	596
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	SIGLEC9 CD320 TLR8 NGFR FLT3 ICAM3 SLC44A1 IGF2R CD6 CSF2RB IL21R TLR2 IL9R	1.56e-04	394	179	13	471
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE2B SPDYE2 SPDYE6	1.97e-04	12	179	3	756
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	2.91e-04	3	179	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	2.91e-04	3	179	2	1189
GeneFamily	Parkinson disease associated genes\|ATPase orphan transporters	ATP13A1 ATP13A2	9.56e-04	5	179	2	1213
GeneFamily	Arachidonate lipoxygenases	ALOX12 ALOX5	1.42e-03	6	179	2	407
Coexpression	GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN	ERCC1 APBB3 RAB30 GNA15 ALOX12 CREB3 PPFIBP1 SEC31B ABCC6 EDNRA GIGYF2	8.01e-06	196	276	11	M8420
Coexpression	GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP	BCAS3 NBEAL2 HS6ST1 KDM2B TPCN2 HDAC6 COP1 ARPC1B TLR2 DKK3 FAM98C	9.70e-06	200	276	11	M7192
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPTOR AGL NGFR BRAT1 ALOX12 HIPK4 GEMIN5 KIF7 SLC22A3	1.36e-07	129	281	9	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS11 HFM1 ALOX12 DNTT PPFIBP1 COL27A1 SYTL4 CLEC14A LSS	1.86e-06	176	281	9	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS11 HFM1 ALOX12 DNTT PPFIBP1 COL27A1 SYTL4 CLEC14A LSS	1.86e-06	176	281	9	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	STARD8 SIGLEC9 PCDH12 TLR8 SVEP1 SPOCD1 THSD7A IL21R TLR2	2.14e-06	179	281	9	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD320 PCDH12 UTRN ANKRD23 TGFBR2 LOXHD1 CLEC14A RP1L1 IPO11	2.80e-06	185	281	9	a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4B HMGCR ABCC8 KDM2B CHPF RET SYTL4 SPHKAP UNC80	4.31e-06	195	281	9	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells\|LPS_only / Treatment groups by lineage, cell group, cell type	IL12B RAB30 GNA15 FLT3 POLD1 NLRP1 ATP13A2 RPUSD1 IL21R	4.68e-06	197	281	9	59ddd8ff7dddf3747b988374e1a4d80959db803e
ToppCell	control-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	STARD8 STAT2 GLB1 GPBAR1 DMXL2 KIAA0930 TPCN2 ARHGEF10L ARHGEF40	4.88e-06	198	281	9	35499a5231818e3432cf69b5c4a58c02f7771db8
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	TSPYL2 DIPK2A UGCG GNA15 NR3C1 ARPC1B IGF2R CSF2RB CNPY3	5.08e-06	199	281	9	2f6074a2fd3323f258be03042f77929640ad0a75
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYD88 TCIRG1 GNA15 UTRN ALOX5 DMXL2 TPCN2 DOK2 TLR2	5.08e-06	199	281	9	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	(54)_pDC\|World / shred on Cell_type and subtype	UGCG MED12L NGFR GNA15 FLT3 MAB21L2 RET ATP13A2 CSF2RB	5.97e-06	203	281	9	b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C2CD4B KIF26A CCDC3 RAPGEF4 ECT2L CSF2RB SYTL4 RP1L1	1.08e-05	166	281	8	a697460dfe72e08fbf7d8e734a16b7dd2c6d86f9
ToppCell	10x5'v1-week_14-16-Lymphocytic_NK-T_NK-NK_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TTC23L FER1L6 ANXA2R GNA15 ISYNA1 KCNG3 CD6 IL9R	1.08e-05	166	281	8	05d3e7f441089d788a192d7fa1ec5c302d1ca202
ToppCell	Control-Mast_cells\|Control / group, cell type (main and fine annotations)	CCDC60 ATP8A2 HS6ST1 MED12L ALOX5 WNK3 SLC44A1 ATP6V0A2	1.23e-05	169	281	8	fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GGT6 CBLC FFAR4 SLC49A3 ALOX5 GPBAR1 CD6 SLC47A1	1.23e-05	169	281	8	818ab7a6fd1940a22d3bd99fe15f0af888af6b3e
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GGT6 CBLC FFAR4 SLC49A3 ALOX5 GPBAR1 CD6 SLC47A1	1.23e-05	169	281	8	f982f2e0d341fa27229f443ebe5c0e4a9e63bda6
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLR8 KIAA0930 CAPN2 RAPGEF4 CELSR3 GIGYF2 LSS PHLPP2	1.23e-05	169	281	8	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	C2CD4B NGFR BRAT1 CRYBG2 EDNRA TG MAPK4 DKK3	1.28e-05	170	281	8	776d4224a682b6c648041827efd69794f88906f0
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHEK1 BRAT1 TPCN2 GARNL3 ZNF473 ECT2L ALG2 SLC44A1	1.28e-05	170	281	8	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	Control-Mast_cells-Mast_cells\|Control / group, cell type (main and fine annotations)	CCDC60 ATP8A2 HS6ST1 MED12L ALOX5 WNK3 SLC44A1 ATP6V0A2	1.28e-05	170	281	8	c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP8A2 ABCC8 GNA15 FOXP3 DOK2 CD6 IL21R IL9R	1.39e-05	172	281	8	ca0cc0e92b6cdce5016f18fcb2ec1508cb222502
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP8A2 ABCC8 GNA15 FOXP3 DOK2 CD6 IL21R IL9R	1.39e-05	172	281	8	425970e9ce8943f7e2ba6ca958e7a3a29baa798c
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8A2 THSD7A RAPGEF4 RPUSD1 AZIN1 IGF2R MICALL2 ERMARD	1.45e-05	173	281	8	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CHRNG SLC49A3 ADGRF3 SPOCD1 ALOX5 DNAH10	1.63e-05	85	281	6	159b3ac93490c3e4918ea61f8ede7add9e63ca40
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR1 CHEK1 CD320 ICAM3 DOK2 CD6	1.86e-05	87	281	6	f92e08c2d1c2f216063ecfd42b06652e558c1a89
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	APBB3 HMGCR CD320 NF1 CHPF B3GNTL1 TVP23B ARHGEF40	1.86e-05	179	281	8	9d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|COVID-19_Convalescent / Disease condition and Cell class	APBB3 HMGCR CD320 NF1 CHPF B3GNTL1 TVP23B ARHGEF40	1.86e-05	179	281	8	366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANGEL1 RET ARHGEF10L CELSR3 PNMA8A SLC47A1 MAB21L1 NIN	1.94e-05	180	281	8	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2CD4B SPTBN2 FFAR4 ABCC8 WNK3 RAPGEF4 ADGRG2 UNC80	2.02e-05	181	281	8	cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCell	5'-Adult-LymphNode-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC60 CHEK1 ZNF473 SPOPL OBSL1 RPUSD1 SMARCB1 IGSF1	2.10e-05	182	281	8	49e4b362f88d235ed12aabcabb54787c16e32cb7
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|normal_Lung / Location, Cell class and cell subclass	DIPK2A UGCG GNA15 FLT3 RET NR3C1 ATP13A2 CSF2RB	2.18e-05	183	281	8	c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF26A RIPOR1 ISYNA1 PPFIBP1 RAPGEF4 CELSR1 TLL1 DKK3	2.45e-05	186	281	8	9579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	VPS11 CCDC3 CHPF2 FOXP3 B3GNTL1 TBCCD1 THADA IGF2R	2.55e-05	187	281	8	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WWC1 PPFIBP1 COL27A1 ABCC6 CELSR1 SLC22A2 LRP2 SLC47A1	2.55e-05	187	281	8	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	UGCG WWC1 PPFIBP1 COL27A1 ABCC6 SLC22A2 LRP2 SLC47A1	2.75e-05	189	281	8	28b502611829e4a24caff2562545c7db97686099
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SIGLEC9 LAMA1 TECPR1 PPFIBP1 RAPGEF4 RET CSF2RB TLL1	2.75e-05	189	281	8	0739baad9a7da511dd3d7249f84299aee88370a1
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD320 PCDH12 ANXA2R UTRN ARPC1B TGFBR2 CLEC14A IPO11	2.85e-05	190	281	8	d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCR ABCC8 CHPF HDAC6 RET SYTL4 SPHKAP UNC80	3.07e-05	192	281	8	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	C2CD4B KIF26A PCDH12 CORO2B THSD7A RAPGEF4 ANGEL1 CLEC14A	3.07e-05	192	281	8	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	normal_Lymph_Node-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	RAB30 KDM2B FLT3 ANKRD10 H6PD NR3C1 CSF2RB IL21R	3.19e-05	193	281	8	024d30eb143d8278c0851c3a6c9426226fa3b480
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2CD4B PCDH12 CHRNG ANXA2R UTRN TGFBR2 CLEC14A IPO11	3.19e-05	193	281	8	807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD320 ANXA2R UTRN ARPC1B TGFBR2 CSF2RB CLEC14A IPO11	3.31e-05	194	281	8	23f2a627226aaed468c55adc42ab22e051dfe7fe
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FFAR4 MED12L ALOX5 GPBAR1 FLT3 CSF2RB QPRT SLC47A1	3.43e-05	195	281	8	c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4B HMGCR ABCC8 HDAC6 RAPGEF4 RET SPHKAP UNC80	3.43e-05	195	281	8	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4B HMGCR ABCC8 HDAC6 RAPGEF4 RET SPHKAP UNC80	3.43e-05	195	281	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Endothelial\|World / shred by cell class for bronchial biopsy	KIF26A PCDH12 C1orf167 TGFBR2 CSF2RB CLEC14A TLL1 IPO11	3.43e-05	195	281	8	f0e46e859f7a9bdead3203889f7e20fa21f76ff0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2CD4B CD320 PCDH12 ANXA2R UTRN TGFBR2 CLEC14A IPO11	3.56e-05	196	281	8	ccf6881c09e570116cf1bcb71112765ea8c28418
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	UGCG NGFR GNA15 FLT3 POLD1 NLRP1 DOK2 ATP13A2	3.69e-05	197	281	8	8fa38fb95e285f9cc756ec4f32009be4ede09d3c
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2CD4B CD320 PCDH12 ANXA2R UTRN TGFBR2 CLEC14A IPO11	3.69e-05	197	281	8	f4834378d5d31560b4efe5dee0d5b5d11caeb10f
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C2CD4B STARD8 ABCC8 HFM1 RAPGEF4 CSF2RB CLEC14A TLL1	3.69e-05	197	281	8	a78111171819db746af7b162c77f9a324453f3ce
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	UTRN PHIP WWC1 OBSL1 CELSR1 SPHKAP SLC22A3 ELF5	3.69e-05	197	281	8	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SIGLEC9 GNA15 ALOX5 FLT3 DOK2 TMEM132E TLR2 CXCL8	3.83e-05	198	281	8	115f564af8d7b89ac0331d3831faaef694043fd4
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD320 THSD7A PPFIBP1 RAPGEF4 TGFBR2 CLEC14A TLL1 IPO11	3.83e-05	198	281	8	13203249e5743ba2699871c184d141207e550a86
ToppCell	LPS_only-Hematopoietic_Myeloid\|LPS_only / Treatment groups by lineage, cell group, cell type	TCIRG1 NBEAL2 GNA15 ALOX5 DMXL2 AZIN1 CSF2RB TLR2	3.96e-05	199	281	8	20523dee39a4c5f6423259920f108127b47525c4
ToppCell	10x5'v1-week_17-19-Myeloid_monocytic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SIGLEC9 GPBAR1 KIAA0930 CAPN2 ICAM3 DOK2 ARPC1B RNH1	3.96e-05	199	281	8	aa30a57c0907d012942e7babdbff6ea4d01d7798
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GPBAR1 DMXL2 KIAA0930 CAPN2 ICAM3 ARPC1B RNH1 CNPY3	3.96e-05	199	281	8	5caaf66b6cddcc8f0d0aee3c9ba80d02075e87e5
ToppCell	10x5'v1-week_17-19-Myeloid_monocytic-monocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SIGLEC9 GPBAR1 KIAA0930 CAPN2 ICAM3 DOK2 ARPC1B RNH1	3.96e-05	199	281	8	7e5a56bb2ac441a8fa4ad0b928f9c0c82d128190
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic-monocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GPBAR1 DMXL2 KIAA0930 CAPN2 ICAM3 ARPC1B RNH1 CNPY3	3.96e-05	199	281	8	7f5d47e49776114d9f4a42017fead9eeb415a94c
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TLR8 FFAR4 GNA15 SPOCD1 ALOX5 DOK2 ARHGEF10L SLC47A1	4.11e-05	200	281	8	6e50272d172b491200d9a255ed08e6d6998cfe02
ToppCell	LPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	UGCG NGFR GNA15 FLT3 POLD1 NLRP1 DOK2 ATP13A2	4.11e-05	200	281	8	6a34e07e6d77fe3fdd9ff44c4b1e46a023f6d6a2
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TLR8 FFAR4 GNA15 SPOCD1 ALOX5 DOK2 ARHGEF10L SLC47A1	4.11e-05	200	281	8	840be665639a53ba9bafc19f7a81ca1e0436e329
ToppCell	LPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TCIRG1 NBEAL2 ALOX5 DMXL2 AZIN1 TG CSF2RB TLR2	4.11e-05	200	281	8	0b7573ec4e9c67c7d11dd8f5011a70bade30e930
ToppCell	LPS_only-Myeloid-Dendritic_cells-mDC\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12B RAB30 GNA15 FLT3 BZW2 NLRP1 IL21R	4.16e-05	147	281	7	26bd9d89e2e7b841cc18030bb7cebb642b987183
ToppCell	LPS_only-Myeloid-Dendritic_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12B RAB30 GNA15 FLT3 NLRP1 ATP13A2 IL21R	4.34e-05	148	281	7	cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCell	(08)_PNEC-(4)_1wkpi\|(08)_PNEC / shred by cell type and Timepoint	ZMIZ1 IGSF1 TBL2	5.09e-05	12	281	3	f1b105bcdbe03be6765c820b42c752a24d502212
ToppCell	Adult-Epithelial-basal_cell-D175\|Adult / Lineage, Cell type, age group and donor	C2CD4B CBLC MED12L NGFR ISYNA1 ELF5 CXCL8	5.36e-05	153	281	7	9ee3e7f3f19a2474283c1c79045269686f35a541
ToppCell	COVID-19-Mast_cells-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	CCDC60 HS6ST1 MED12L ALOX5 WNK3 SLC44A1 IL9R	6.06e-05	156	281	7	bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC60 ATP8A2 CORO2B ALOX5 TAS1R3 COL27A1 OBSL1	6.06e-05	156	281	7	58b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCell	COVID-19-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	CCDC60 HS6ST1 MED12L ALOX5 WNK3 SLC44A1 IL9R	6.06e-05	156	281	7	159504d43421ee83b9ab484816333ae549c9c2fd
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Batf3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UTRN WWC1 PRSS12 GPR88 MAP3K6 CDYL2 DKK3	6.31e-05	157	281	7	921805932f7974d37aed547861d555b07f30aba6
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GNA15 ALOX12 FLT3 ICAM3 LCAT KIF7 CELSR1	6.31e-05	157	281	7	d12f343454202da86a06d0369f8ffe5662cd091b
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 SVEP1 DNAH10 SPHKAP TLL1 LRP2 UNC80	7.11e-05	160	281	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 SVEP1 DNAH10 SPHKAP TLL1 LRP2 UNC80	7.11e-05	160	281	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SPOCD1 DOK2 ERI2 TBCCD1 IGF2R CELSR3 PNMA8A	7.11e-05	160	281	7	955acb023ce4ccfac5073c9d693db87db3856187
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma\|TCGA-Brain / Sample_Type by Project: Shred V9	CDHR1 HMGCR ABCC8 KCNJ9 CELSR3 UNC80 PHLPP2	7.40e-05	161	281	7	5f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	FFAR4 FANCE SSC4D PELO SLC49A3 SPOCD1 ARHGEF10L	7.69e-05	162	281	7	7d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCell	LPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCC8 TPCN2 NLRP1 ABCC6 CDYL2 SLC47A1	7.74e-05	112	281	6	9801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLB1 KDM2B B3GNTL1 THSD7A TBL1XR1 CELSR1 SLC22A1	7.99e-05	163	281	7	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLB1 KDM2B B3GNTL1 THSD7A TBL1XR1 CELSR1 SLC22A1	7.99e-05	163	281	7	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD2 MAB21L2 CELSR3 SPHKAP TLL1 MAB21L1 UNC80	8.96e-05	166	281	7	ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAT3 GNA15 DOK2 CD6 IL21R ZFYVE26 IL9R	9.30e-05	167	281	7	38b1f052d663fa8f407c54bdd2060216f26feb0e
ToppCell	droplet-Lung-nan-3m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8A2 ABCC8 FOXP3 CRYBG2 DOK2 CD6 IL21R	9.65e-05	168	281	7	1586451d437b70b2dffe41d782b694702dcaf50b
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8A2 ABCC8 FOXP3 CRYBG2 DOK2 CD6 IL21R	9.65e-05	168	281	7	1df3c8c7a6dceb901805eaba7f86f9943f4f1a9d
ToppCell	10x5'-GI_small-bowel-Myeloid_Mac-Macrophage\|GI_small-bowel / Manually curated celltypes from each tissue	IL12B SPOCD1 ALOX5 GPBAR1 DMXL2 TLR2 CXCL8	9.65e-05	168	281	7	d5b746d6083c2c8155a0ea345ea368bf6617d5ca
ToppCell	Control-Epithelial_alveolar-AT_2-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GDF5 SPTBN2 YDJC WWC1 SLC22A3 ELF5	9.85e-05	117	281	6	c6fc72608d56a389bcd87b5dc98a11e39b79bcb2
ToppCell	COVID-19-lung-MAST\|lung / Disease (COVID-19 only), tissue and cell type	PARP4 HS6ST1 ALOX5 SLC44A1 MAB21L1 ATP6V0A2 IL9R	1.04e-04	170	281	7	e90f18e5462381b38e918442b38b1c8105291908
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12B FFAR4 FLT3 ISYNA1 GRAMD2A ARHGEF40 DKK3	1.04e-04	170	281	7	bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SPTBN2 HS6ST1 GNA15 ISYNA1 CSF2RB TMEM132E ATP6V0A2	1.12e-04	172	281	7	7fb43b3938b9a3b6935ec22d9d853e7d47b82b3c
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCIRG1 STN1 GNA15 HDAC6 PPFIBP1 ATP13A2 LTN1	1.12e-04	172	281	7	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCIRG1 STN1 GNA15 HDAC6 PPFIBP1 ATP13A2 LTN1	1.12e-04	172	281	7	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHEK1 FFAR4 YDJC GNA15 KIAA0930 FLT3 MICALL2	1.20e-04	174	281	7	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	RPTOR COL27A1 EDNRA IGF2R TLL1 LSS DKK3	1.20e-04	174	281	7	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	droplet-Liver-LIVER-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKLE1 CORO2B CCDC117 TMEM132E CLEC14A DKK3 IPO11	1.29e-04	176	281	7	4d2fb51e71bed0d72f3d7f89d395744860885a5f
ToppCell	droplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKLE1 CORO2B CCDC117 TMEM132E CLEC14A DKK3 IPO11	1.29e-04	176	281	7	4880fa20b50eb10358e08567e08559ef2954f237
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	LZTR1 UGCG GNA15 DMXL2 FLT3 ATP13A2 CSF2RB	1.29e-04	176	281	7	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	droplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKLE1 CORO2B CCDC117 TMEM132E CLEC14A DKK3 IPO11	1.29e-04	176	281	7	fcdddd949ca05b3ecde240db9e38296a6eab2d6a
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAT2 GLB1 VPS33B AGL TPCN2 DKK3	1.30e-04	123	281	6	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	metastatic_Lymph_Node-Endothelial_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	PCDH12 CCDC3 PPFIBP1 RET CLEC14A TLL1 IPO11	1.34e-04	177	281	7	71bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	APBB3 PEAK3 KDM2B DMXL2 KIAA0930 TLR2 CXCL8	1.34e-04	177	281	7	f28243b51be104cb3adcde63f03fc2206ed3121e
ToppCell	facs-Marrow-KLS-24m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKLE1 RIPOR1 DNTT FLT3 HIPK4 BZW2 RPUSD1	1.43e-04	179	281	7	5297f7459b40ca780a1983fecc1bb9c035c7677e
Drug	AC1L973H	MYD88 VPS11 LAMA1 TLR8 GLB1 GBA2 TLR2 IFT122	4.16e-07	57	276	8	CID000439306
Drug	Cyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TMEM94 SPTBN2 HLCS STAT2 PASK ALOX12 CRYBG2 TNPO2 RANBP3 IL17RC NR3C1 TGFBR2	5.80e-06	198	276	12	3882_DN
Drug	Fenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A	SPTBN2 NEK9 SVEP1 PASK NF1 UTRN ALOX5 CLBA1 IL17RC MAB21L2 H6PD CD6	6.43e-06	200	276	12	5432_UP
Drug	4-(4-dimethylaminostyryl)-1-methylpyridinium	SLC22A1 SLC22A2 SLC47A1	6.99e-06	4	276	3	ctd:C032315
Disease	anogenital venereal wart (is_marker_for)	MYD88 IL12B TLR8 FOXP3 TLR2	3.35e-06	26	268	5	DOID:11168 (is_marker_for)
Disease	Neurofibromatosis 3	LZTR1 NF1 SMARCB1	7.31e-06	5	268	3	C0917817
Disease	Intellectual Disability	TMEM94 ATP8A2 TBC1D7 LAMA1 PCDH12 NF1 NXF5 MED12L PHIP ZMIZ1 KIF7 SUPT16H LRP2 LSS MAB21L1	1.67e-05	447	268	15	C3714756
Disease	Colorectal Carcinoma	STARD8 SPTBN2 LAMA1 CORO2B NF1 ABCC8 MCM3AP PHIP NLRP8 POLD1 ZMIZ1 RET ERI2 ABCC6 ARHGEF10L TGFBR2 TLR2 LRP2 CXCL8	2.62e-05	702	268	19	C0009402
Disease	total lipids in small LDL	HMGCR KPNB1 SLC22A1 SLC22A3 SLC22A2	6.69e-05	47	268	5	EFO_0022168
Disease	neurilemmomatosis (is_implicated_in)	LZTR1 SMARCB1	8.22e-05	2	268	2	DOID:3204 (is_implicated_in)
Disease	intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)	TNPO1 TNPO2	8.22e-05	2	268	2	DOID:0081262 (implicated_via_orthology)
Disease	Eye Infections, Bacterial	TLR2 CXCL8	8.22e-05	2	268	2	C0015404
Disease	Schwannomatosis	LZTR1 SMARCB1	8.22e-05	2	268	2	cv:C1335929
Disease	coronary artery disease	VPS11 BCAS3 TBC1D7 HMGCR ZFPM1 NEK9 SVEP1 STN1 VPS33B RPTOR MMP24OS NME7 THSD7A DNAH10 EDNRA RSBN1 THADA IGF2R MAP1S SLC22A1 KCTD10 SLC22A3 SLC22A2 GIGYF2 CXCL8	1.01e-04	1194	268	25	EFO_0001645
Disease	Kidney Diseases	RGN SLC22A2 LRP2 SLC47A1 SMPD1 IFT122	1.54e-04	88	268	6	C0022658
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	CBLC HMGCR FFAR4 PELO KPNB1 DNAH10 SPG11 IGF2R KCTD10 SLC22A2	1.64e-04	264	268	10	EFO_0008317, EFO_0020944
Disease	SCHWANNOMATOSIS 1	LZTR1 SMARCB1	2.45e-04	3	268	2	C4048809
Disease	Keratitis	TLR2 CXCL8	2.45e-04	3	268	2	C0022568
Disease	X-24422 measurement	IGF2R SLC22A1	2.45e-04	3	268	2	EFO_0800880
Disease	X-11261 measurement	IGF2R SLC22A1	2.45e-04	3	268	2	EFO_0021221
Disease	Abnormality of the genital system	LSS MAB21L1	2.45e-04	3	268	2	C0744356
Disease	Knee pain	GDF5 COL27A1	2.45e-04	3	268	2	HP_0030839
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1XR1	2.45e-04	3	268	2	DOID:0050155 (implicated_via_orthology)
Disease	duodenal ulcer	FLT3 TPCN2 SLC22A3 SLC22A2	3.12e-04	36	268	4	EFO_0004607
Disease	cholesterol in large VLDL measurement	HMGCR DNAH10 IGF2R SLC22A3 SLC22A2	3.15e-04	65	268	5	EFO_0021902
Disease	chronic kidney disease	BCAS3 VPS33B AGL THSD7A MICALL2 SLC22A2 LRP2 SLC47A1 CXCL8	3.19e-04	235	268	9	EFO_0003884
Disease	total lipids in small VLDL	HMGCR DNAH10 IGF2R SLC22A3 SLC22A2	3.63e-04	67	268	5	EFO_0022148
Disease	familial hyperlipidemia	ERCC1 CBLC HMGCR IGF2R SLC22A3 SLC22A2	4.24e-04	106	268	6	MONDO_0001336
Disease	gastritis (is_implicated_in)	ARPC1B CXCL8	4.87e-04	4	268	2	DOID:4029 (is_implicated_in)
Disease	Schwannomatosis	LZTR1 SMARCB1	4.87e-04	4	268	2	C1335929
Disease	arachidoylcarnitine (C20) measurement	PCDH12 TPCN2	4.87e-04	4	268	2	EFO_0800540
Disease	cation-independent mannose-6-phosphate receptor measurement	IGF2R SLC22A1	4.87e-04	4	268	2	EFO_0008075
Disease	Neurofibromatosis, Type 3, mixed central and peripheral	LZTR1 SMARCB1	4.87e-04	4	268	2	C2931480
Disease	cholesteryl ester measurement	HMGCR YDJC KPNB1 DNAH10 LCAT IGF2R SLC22A1 SLC22A3 SLC22A2	6.10e-04	257	268	9	EFO_0010351
Disease	psoriasis, type 2 diabetes mellitus	IL12B STAT2 ZMIZ1 THADA ADO	6.12e-04	75	268	5	EFO_0000676, MONDO_0005148
Disease	total cholesterol measurement, low density lipoprotein cholesterol measurement	CBLC HMGCR PELO KPNB1 IGF2R SLC22A1	6.24e-04	114	268	6	EFO_0004574, EFO_0004611
Disease	creatinine measurement, glomerular filtration rate	BCAS3 THADA MICALL2 SLC22A2 LRP2 SLC47A1	7.16e-04	117	268	6	EFO_0004518, EFO_0005208
Disease	Abnormality of head or neck	TMEM94 ZMIZ1	8.07e-04	5	268	2	C4021817
Disease	Q Fever	HMGCR LSS	8.07e-04	5	268	2	C0034362
Disease	intrahepatic cholestasis (biomarker_via_orthology)	SLC22A1 SLC22A2	8.07e-04	5	268	2	DOID:1852 (biomarker_via_orthology)
Disease	juvenile myelomonocytic leukemia (implicated_via_orthology)	NF1 FLT3	8.07e-04	5	268	2	DOID:0050458 (implicated_via_orthology)
Disease	Staphylococcal Infections	TLR2 CXCL8	8.07e-04	5	268	2	C0038160
Disease	Coxiella burnetii Infection	HMGCR LSS	8.07e-04	5	268	2	C2973787
Disease	Wilson disease (implicated_via_orthology)	HMGCR SMPD1	8.07e-04	5	268	2	DOID:893 (implicated_via_orthology)
Disease	Acute Q fever	HMGCR LSS	8.07e-04	5	268	2	C0519066
Disease	Chronic Q Fever	HMGCR LSS	8.07e-04	5	268	2	C1443892
Disease	autosomal recessive osteopetrosis 1 (implicated_via_orthology)	TCIRG1 ATP6V0A2	8.07e-04	5	268	2	DOID:0110942 (implicated_via_orthology)
Disease	Staphylococcus aureus infection	TLR2 CXCL8	8.07e-04	5	268	2	C1318973
Disease	free cholesterol in medium VLDL measurement	HMGCR SLC22A1 SLC22A3 SLC22A2	8.73e-04	47	268	4	EFO_0022269
Disease	lung disease (is_implicated_in)	NR3C1 EDNRA TLR2	1.00e-03	22	268	3	DOID:850 (is_implicated_in)
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	CBLC HMGCR FFAR4 PELO KPNB1 SPG11 IGF2R SLC22A2	1.01e-03	222	268	8	EFO_0008317, EFO_0020943
Disease	Colorectal Neoplasms	STARD8 LAMA1 ABCC8 POLD1 ZMIZ1 RET ABCC6 TLR2 CXCL8	1.04e-03	277	268	9	C0009404
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	CBLC HMGCR FFAR4 KPNB1 SPG11 IGF2R SLC22A3 SLC22A2	1.10e-03	225	268	8	EFO_0008317, EFO_0020947
Disease	Eye Diseases, Hereditary	LRP2 RPE65	1.20e-03	6	268	2	C0015398
Disease	Abnormal corpus callosum morphology	MED12L SUPT16H	1.20e-03	6	268	2	C1842581
Disease	urinary tract infection (is_implicated_in)	TLR2 CXCL8	1.20e-03	6	268	2	DOID:0080784 (is_implicated_in)
Disease	clubfoot (implicated_via_orthology)	TCIRG1 RET	1.20e-03	6	268	2	DOID:11836 (implicated_via_orthology)
Disease	myelofibrosis (is_marker_for)	ERCC1 FLT3	1.20e-03	6	268	2	DOID:4971 (is_marker_for)
Disease	angiostatin measurement	SLC22A3 SLC22A2	1.20e-03	6	268	2	EFO_0008024
Disease	phospholipids in medium VLDL measurement	HMGCR IGF2R SLC22A3 SLC22A2	1.28e-03	52	268	4	EFO_0022154
Disease	polyunsaturated fatty acid measurement	HMGCR KPNB1 LCAT SLC22A1 SLC22A3 SLC22A2	1.29e-03	131	268	6	EFO_0010733
Disease	cholesterol in small VLDL measurement	HMGCR IGF2R SLC22A3 SLC22A2	1.37e-03	53	268	4	EFO_0022228
Disease	hepatocellular carcinoma (is_implicated_in)	MYD88 LZTR1 FLT3 AZIN1 IGF2R TLR2 CXCL8	1.39e-03	181	268	7	DOID:684 (is_implicated_in)
Disease	Global developmental delay	TMEM94 SPTBN2 ZMIZ1 SUPT16H LSS MAB21L1	1.39e-03	133	268	6	C0557874
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	CBLC HMGCR FFAR4 KPNB1 DNAH10 SPG11 IGF2R SLC22A1 SLC22A2	1.46e-03	291	268	9	EFO_0008317, EFO_0020946
Disease	sleep duration, low density lipoprotein cholesterol measurement	CBLC HMGCR KPNB1 IGF2R SLC22A1	1.47e-03	91	268	5	EFO_0004611, EFO_0005271
Disease	primary biliary cholangitis (is_marker_for)	FOXP3 NR3C1 CXCL8	1.47e-03	25	268	3	DOID:12236 (is_marker_for)
Disease	total lipids in medium VLDL	HMGCR IGF2R SLC22A3 SLC22A2	1.47e-03	54	268	4	EFO_0022153
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	CBLC HMGCR PELO KPNB1 IGF2R SLC22A1	1.62e-03	137	268	6	EFO_0004611, EFO_0008591
Disease	acisoga measurement	IGF2R SLC22A1	1.67e-03	7	268	2	EFO_0800068
Disease	Eosinophilia, Tropical	MYD88 TLR2	1.67e-03	7	268	2	C0014458
Disease	lipoprotein A measurement, apolipoprotein A 1 measurement	SLC22A3 SLC22A2	1.67e-03	7	268	2	EFO_0004614, EFO_0006925
Disease	total lipids in large LDL	HMGCR PELO KPNB1 IGF2R	1.80e-03	57	268	4	EFO_0022163
Disease	cholesterol in large LDL measurement	HMGCR PELO KPNB1 IGF2R	1.80e-03	57	268	4	EFO_0021901
Disease	acute kidney failure (implicated_via_orthology)	ALOX5 SLC22A1 SLC22A2	1.84e-03	27	268	3	DOID:3021 (implicated_via_orthology)
Disease	phospholipids in VLDL measurement	HMGCR IGF2R SLC22A3 SLC22A2	2.05e-03	59	268	4	EFO_0022301
Disease	phospholipids in small LDL measurement	HMGCR PELO KPNB1 IGF2R	2.05e-03	59	268	4	EFO_0022297
Disease	phospholipids in small VLDL measurement	HMGCR SLC22A1 SLC22A3 SLC22A2	2.18e-03	60	268	4	EFO_0022146
Disease	argininate measurement	IGF2R SLC22A1	2.22e-03	8	268	2	EFO_0800055
Disease	NRF2 measurement	RPP40 TGFBR2	2.22e-03	8	268	2	EFO_0009794
Disease	leprosy (is_implicated_in)	TLR2 CXCL8	2.22e-03	8	268	2	DOID:1024 (is_implicated_in)
Disease	Eosinophilia	MYD88 TLR2	2.22e-03	8	268	2	C0014457
Disease	pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC) measurement	IGF2R SLC22A1	2.22e-03	8	268	2	EFO_0800494
Disease	renal tubular acidosis (implicated_via_orthology)	TCIRG1 ATP6V0A2	2.22e-03	8	268	2	DOID:14219 (implicated_via_orthology)
Disease	coronary artery disease (is_implicated_in)	HMGCR C1orf167 NR3C1 ABCC6 TLL1	2.22e-03	100	268	5	DOID:3393 (is_implicated_in)
Disease	monocyte count	BCAS3 SPTBN2 ZFPM1 TLR8 NF1 TBC1D14 MED12L HFM1 GNA15 TNPO1 GPBAR1 CRYBG2 FLT3 DOK2 ZMIZ1 RSBN1 THADA ADO KCTD10 SLC22A3 CDYL2 MAPK4 URAD	2.27e-03	1320	268	23	EFO_0005091
Disease	free cholesterol in VLDL measurement	HMGCR IGF2R SLC22A3 SLC22A2	2.31e-03	61	268	4	EFO_0022276
Disease	alkaline phosphatase measurement	SIGLEC9 ZFPM1 NWD2 NF1 HS6ST1 HFM1 CHPF2 UTRN ATP13A1 ZMIZ1 AZIN1 RSBN1 SLC4A1AP SLC22A1 SLC22A2 RP1L1 CDYL2 TBL2 PHLPP2	2.49e-03	1015	268	19	EFO_0004533
Disease	cholesteryl esters to total lipids in large LDL percentage	LCAT SLC22A3 SLC22A2	2.76e-03	31	268	3	EFO_0022249
Disease	X-11381 measurement	IGF2R SLC22A1	2.84e-03	9	268	2	EFO_0021228
Disease	tropical spastic paraparesis (is_marker_for)	FOXP3 CXCL8	2.84e-03	9	268	2	DOID:321 (is_marker_for)
Disease	obsolete_red blood cell distribution width	BCAS3 C19orf47 ZFPM1 VPS33B UGCG TBC1D14 KDM2B YDJC HFM1 WNK3 KPNB1 CCDC117 ASNSD1 TNPO1 FLT3 BZW2 TBL1XR1 GBA2 LOXHD1 KCTD10 RP1L1 SLC47A1 TBL2	2.92e-03	1347	268	23	EFO_0005192
Disease	apolipoprotein A 1 measurement, apolipoprotein B measurement	CBLC HMGCR KPNB1 DNAH10 SLC22A1	2.98e-03	107	268	5	EFO_0004614, EFO_0004615
Disease	remnant cholesterol measurement	CBLC HMGCR KPNB1 IGF2R SLC22A1	3.10e-03	108	268	5	EFO_0010815
Disease	apolipoprotein B measurement	ERCC1 CBLC HMGCR NF1 PELO KPNB1 DNAH10 THADA IGF2R SLC4A1AP SLC22A1 SLC22A3 SLC22A2 CNPY3	3.18e-03	663	268	14	EFO_0004615
Disease	lymphocyte percentage of leukocytes	C19orf47 STAT2 HS6ST1 RAB30 TBC1D14 KDM2B YDJC FLT3 ATP13A1 ZMIZ1 NR3C1 THADA SLC47A1 CXCL8	3.27e-03	665	268	14	EFO_0007993
Disease	reticulocyte count	BCAS3 TCIRG1 ZFPM1 FFAR4 PELO YDJC SPOCD1 ALOX5 GPBAR1 KLHL10 TPCN2 DNAH10 BZW2 GEMIN5 ARPC1B STK16 THADA RNH1 LTN1	3.42e-03	1045	268	19	EFO_0007986
Disease	cutaneous leishmaniasis (is_marker_for)	FOXP3 TLR2	3.52e-03	10	268	2	DOID:9111 (is_marker_for)
Disease	obesity (implicated_via_orthology)	MED12L GPR12 HDAC6 DNAH10 CAPN2 NR3C1 THADA	3.64e-03	215	268	7	DOID:9970 (implicated_via_orthology)
Disease	free cholesterol measurement	CBLC HMGCR KPNB1 IGF2R SLC22A1	3.77e-03	113	268	5	EFO_0008591
Disease	anorexia nervosa	PHIP THSD7A CELSR3 LRP2	3.81e-03	70	268	4	MONDO_0005351
Disease	hepatitis C (is_marker_for)	STAT2 FOXP3 CXCL8	3.91e-03	35	268	3	DOID:1883 (is_marker_for)
Disease	lymphocyte count	BCAS3 TBC1D7 C19orf47 ZFPM1 HS6ST1 MCM3AP TBC1D14 MED12L RIPOR1 HFM1 TNPO1 FLT3 TPCN2 B3GNTL1 DNAH10 ICAM3 DOK2 ZMIZ1 EDNRA RSBN1 THADA CD6 ADO SLC47A1	3.97e-03	1464	268	24	EFO_0004587
Disease	factor XI measurement, coronary artery disease	BCAS3 NME7 EDNRA IGF2R MAP1S	4.06e-03	115	268	5	EFO_0001645, EFO_0004694

Protein segments in the cluster

Peptide	Gene	Start	Entry
ATERCPLIAAAVWSQ	URAD	21	A6NGE7
QEARSLWTCPEDREP	AEN	276	Q8WTP8
FRGVLEEQCRWLDPD	ADAT3	336	Q96EY9
SAVCWRALPDGESNV	COP1	701	Q8NHY2
SSTLDCLPVLADWED	ERI2	396	A8K979
NDLPETAVIGLLWTC	BZW2	286	Q9Y6E2
EVLTDSEGWILIDRC	KCTD10	66	Q9H3F6
HPCWEVRDSALEFLT	BRAT1	511	Q6PJG6
DGDITCPEDASVLTW	ADGRF3	426	Q8IZF5
KRITEAELCAGPNDW	CCDC117	86	Q8IWD4
TAPESEAICWQLLSR	C1orf167	501	Q5SNV9
EDAVWASCGPRVTVL	ARHGEF10L	981	Q9HCE6
APCGETDSTLLIWQV	ARHGEF10L	1261	Q9HCE6
GASILPLCDLVWANE	CDY2A	396	Q9Y6F7
PGRDCLWSLEVQAKD	CDHR1	646	Q96JP9
ACSLPARVEEEAWDL	ARHGEF40	1441	Q8TER5
WAVEELLRCGADPNL	ANKLE1	21	Q8NAG6
SCIASRPSWVEDIGD	ANKRD10	356	Q9NXR5
DARDLLDRTPVFWAC	ANKRD23	171	Q86SG2
VVSWRLEPEDGTALC	BAGE	26	Q13072
ARCVLPWAEFESLLG	CBLC	166	Q9ULV8
AEPVDVWSCGIVLTA	CHEK1	186	O14757
ACWGRAAADESVQLP	C19orf47	11	Q8N9M1
SSLWGPSCDELDQIV	AZIN1	351	O14977
SSACDLPREVWLLET	ADO	236	Q96SZ5
EVWRRSVLSPSEACG	SMPD1	146	P17405
WSITTGEEVALCLPR	CHRNG	381	P07510
TGIDWAPESNRIVTC	ARPC1B	56	O15143
QCEWRSIDGSIVLPL	ATP13A1	781	Q9HD20
ELVVNPWDIVLCTSG	GPR12	41	P47775
PSQDELTVRCVFWDL	ADGRG2	561	Q8IZP9
WLALVGCVISDNPER	EDNRA	11	P25101
IACVSHLDWLTPREA	ECT2L	146	Q008S8
VWAPADLRVVDCSCR	CENPVL1	146	A0A0U1RR11
HDGVCRLWAETLLPE	DMXL2	261	Q8TDJ6
SGWITVCAELDREEV	CELSR1	636	Q9NYQ6
ELHSVSWLPQELDRC	DNHD1	416	Q96M86
IEPTELSENCFWLRV	DIAPH2	646	O60879
FDRSVTLLEVCGSWP	BCAS3	826	Q9H6U6
LGCVKRAWDSAEVAP	ANXA2R	6	Q3ZCQ2
WEFVRDLLLSPEENC	ELF5	176	Q9UKW6
DLLLSPEENCGILEW	ELF5	181	Q9UKW6
FLVPTACLIEDVAWR	ATP8A2	1076	Q9NTI2
DLRIWELCSPDIAVA	CCDC60	501	Q8IWA6
LLEEWYCRDENSVPA	NWD2	156	Q9ULI1
AWRSPSEAADEVCAL	RANBP3	216	Q9H6Z4
GAWAVPRVDCLIDTL	ANKRD33	31	Q7Z3H0
ITCEESFRCLPEWLR	RAB30	91	Q15771
LWTANTERFCEVIPG	ISYNA1	226	Q9NPH2
RGDLEHLEDTAWTPC	KCNJ9	86	Q92806
WDPCLVSFDVLATGD	PCDH12	101	Q9NPG4
VVLCASTLPDWRNAA	KCNG3	186	Q8TAE7
SEDCSPQGEWTILEL	KIAA1107	1261	Q9UPP5
AVLLSPDLQAEEWSC	MAMDC2	66	Q7Z304
DDSDPIVCPALWEAV	LTN1	306	O94822
GTVEVRLEASWEPAC	CD6	56	P30203
WSRDGEELPVICQSS	OBSL1	461	O75147
GVWRVVCRDPTQDAE	PNMA8A	91	Q86V59
SVTDFGAPCLRWAEV	PRSS12	101	P56730
PWLGVENDREELQTC	PASK	646	Q96RG2
ERGDWVQAICLLAFP	DOK2	101	O60496
DLDLDRWEDIGCALP	KLHL34	596	Q8N239
WLDLEFICTVLGAPD	GDF5	16	P43026
SLLLLCEEEESWAGR	GPR88	16	Q9GZN0
CEEEESWAGRRIPVS	GPR88	21	Q9GZN0
IACLGVTDTDWRELA	IFT122	636	Q9HBG6
IRSWDVDPGVCNLDE	MAP1S	41	Q66K74
PNDEAVVTLLCEWAV	MED12L	501	Q86YW9
ELTCWEEVAQSGEIP	LZTR1	211	Q8N653
SRLALWESEGPEAFC	MAGEC3	316	Q8TD91
SSCPGWLRKELENAE	NEK9	806	Q8TD19
ASLEWVSREPALLCT	FOXP3	156	Q9BZS1
EWLSEPDCTLESVRG	HIPK4	571	Q8NE63
TFADCISDELPLGWE	WWC1	46	Q8IX03
EDCLATPRIWTDLGN	NLRP8	796	Q86W28
RCQIPDSTAETLVEW	PPFIBP1	71	Q86W92
VCRDEPSALARALTW	GPBAR1	206	Q8TDU6
LSSDLEWRPDRCQDA	MAPK4	361	P31152
LPRACDSAEVKAWLE	HMGCR	596	P04035
ELRCTLSDDCIPLTW	CD320	136	Q9NPF0
DGLELWLVTLENSPC	IPO11	666	Q9UI26
GPLDDVRFLIACTSW	MMP24OS	56	A0A0U1RRL7
EQSPESCGRILANWL	MCM3AP	1371	O60318
PDIDWEESVCLNLIL	KIAA0930	96	Q6ICG6
WLVEELCLAVPTQGT	LOXHD1	1501	Q8IVV2
LEDSALRDPWTDNCL	HLCS	201	P50747
ITVLELEWAPCSSDD	GLB1	616	P16278
AAAVPRRCAAESDLW	C2CD4B	51	A6NLJ0
LADCTLILAWSPEEA	ERCC1	191	P07992
ERAGSCWQDPLAVAL	MAP3K6	11	O95382
RLAVPASLDVCDNWL	MICALL2	666	Q8IY33
GADQEISICTLIWPT	FFAR4	186	Q5NUL3
LEELWLEGNPLCSTF	NXF5	211	Q9H1B4
EVPERTVAQWLAEAC	PEAK3	256	Q6ZS72
PQLRDLCSLAAEGIW	NLRP1	566	Q9C000
PVCVDLGDWEATERA	DCXR	56	Q7Z4W1
LLVDEACWLRTLPQA	ZFPM1	141	Q8IX07
ACWLRTLPQALTEAE	ZFPM1	146	Q8IX07
TEPATDLGRWRLNCE	LSS	16	P48449
RDWLCAVEGERSALS	KIF7	441	Q2M1P5
LCVSDRDVLPGTCVW	MYD88	191	Q99836
RDVLPGTCVWSIASE	MYD88	196	Q99836
DPWLLRVGECDTQAA	KIF26A	1241	Q9ULI4
SPWRSDLLIDENCLL	NR3C1	211	P04150
AALVDSWLREDCPGL	QPRT	16	Q15274
WSLSPDLLNCLRDDQ	LRP2	1731	P98164
PWCLTEDEKAAARVD	GNA15	11	P30679
DDIVKGDPELQAWCR	ALOX12	486	P18054
GDPELQAWCREITEV	ALOX12	491	P18054
ICPRLELGNDWDSAT	PARP4	1686	Q9UKK3
EDSIPCTCDLRWRAS	GARIN1B	291	Q96KD3
VVLTCDTPEEDGITW	IL12B	46	P29460
ADWTELTNCVPGVLD	HS6ST1	151	O60243
LEVETSWPVDCTLDG	ICAM3	231	P32942
LVADRTSEALPLCWQ	NUTM1	611	Q86Y26
IAEWLSDGERPAVCL	HFM1	466	A2PYH4
EPIVEWVLCDSQGES	FLT3	191	P36888
EASTEEEPLWQCPVR	APBB3	346	O95704
WVDSSELVPGDCLVL	ATP13A2	306	Q9NQ11
CWERSLAGAEETIPL	CSF2RB	16	P32927
CRVSHPVLEFSLEWE	IGSF1	441	Q8N6C5
DRWVNVTCEEESPRA	KLHL10	316	Q6JEL2
SCPLLRTLDVQWVEG	KDM2B	1171	Q8NHM5
CSEDTSVRIWEIPEG	CORO2B	106	Q9UQ03
GSIDDDRDSLPEWCL	GIGYF2	276	Q6Y7W6
VWAPADLRVVDCSCR	CENPVL2	146	P0DPI3
SWLQCVEDRSIAGIP	LINC01599	186	Q8WXQ3
WNEPFCLERSGETVR	GBA2	306	Q9HCG7
SEWRPLSEGCRAELA	CCDC3	26	Q9BQI4
LTPEAVEGWSDLVHC	DIPK2A	156	Q8NDZ4
SAWACPLILRGSLDD	GGT6	396	Q6P531
GAEENDWVRLPSKCE	CNPY3	36	Q9BT09
VWAPADLRVVDCSCR	CENPVL3	146	A0A0U1RRI6
CELWQVLGAPSSTEL	CRYBG2	326	Q8N1P7
SCPEDEVLRNNELSW	HYAL4	236	Q2M3T9
LDSHCEVNRVWLEPL	GALNTL5	226	Q7Z4T8
WICDSGIRVIPDTLT	UGCG	141	Q16739
WVDPNLGCSSDTIEV	COL27A1	1706	Q8IZC6
PRETDWDESCLGDRL	MAB21L2	286	Q9Y586
DTAAWTVGRICELLP	KPNB1	426	Q14974
PLDTVLDDSIGCAVW	ASNSD1	451	Q9NWL6
LLSCSLDAPRWEALE	FAM98C	201	Q17RN3
IRVFDTRTEAWLDCP	KLHDC3	216	Q9BQ90
FLPLGVDCWIDNTRV	LCAT	91	P04180
RTCAGEDRPEVWQVD	KRBOX4	76	Q5JUW0
LEDRSCTDIPWLLLF	SLC44A1	21	Q8WWI5
IDTVTVLDAEGPCTW	IL21R	376	Q9HBE5
LSCEESIRVWALLPF	ERMARD	441	Q5T6L9
CEDWPEAQRISASLL	EMC8	161	O43402
EPFDWGRLLEALCRE	FANCE	56	Q9HB96
CALEALEPFWEVLVR	HDAC6	426	Q9UBN7
VRLCDEAQGWLEPDL	CELSR3	2161	Q9NYQ7
PDERTISLCCWDSRT	CSTF1	371	Q05048
RLEQQLCSLSWDDPV	GRAMD2A	336	Q8IUY3
LWLVDERCVPLSDPE	H6PD	616	O95479
VVSWRLEPEDGTALC	BAGE5	26	Q86Y27
CPSWNTIDPEERERL	CAPN2	301	P17655
LSEVPSDWEVDDLLC	CREB3	41	O43889
SDWEVDDLLCSLLSP	CREB3	46	O43889
WDREPDELNIRQCTG	DNAH10	1776	Q8IVF4
AELSQRCGWSPAEEL	SLC22A1	56	O15245
VAELSLRCGWSPAEE	SLC22A2	56	O15244
AAALAERCGWSPEEE	SLC22A3	56	O75751
LITWELEPDGALDRC	DKK3	251	Q9UBP4
VDTDIVGCNWLELPA	POLD1	256	P28340
DDAICEWKRLLGPAN	NME7	166	Q9Y5B8
EAVCADPWGQALLVS	GARNL3	491	Q5VVW2
RLWDSDILCLPGDIV	IL17RC	111	Q8NAC3
CSEDNRILLWDTRCP	WDR77	186	Q9BQA1
CTDSEDQPRTAGEIW	OTOGL	1866	Q3ZCN5
PEVSCRALELFDWLG	RPP40	231	O75818
VLHSWEDIPEVGCRL	FER1L6	1531	Q2WGJ9
WRTVEACPVVRVEGD	IGF2R	1211	P11717
VFERNLCWTLPADCL	PUSL1	146	Q8N0Z8
ETEAQRGPCLQWLSE	RPUSD1	291	Q9UJJ7
KWRAEERLQCPAGSA	RSBN1	11	Q5VWQ0
CLELTVWDREPLASN	SYTL4	596	Q96C24
AIEVLSTEDCVRWPS	PARS2	351	Q7L3T8
WITEAEELLVDTCAP	UTRN	1991	P46939
SERVALCNWAELTPE	ROPN1B	56	Q9BZX4
ATAILCSDETIWLEP	RPE65	391	Q16518
SSAEWIACLDKRPLE	RAPGEF4	11	Q8WZA2
EPECPDAELRATLQW	SPHKAP	1616	Q2M3C7
SRCEEETPSLLWGLD	STN1	6	Q9H668
ARLEARWSAALPCAE	TRMT44	41	Q8IYL2
VLLRSVDCTSVPEWF	THADA	276	Q6YHU6
GQNCRTEDPLLSWAD	STAT2	526	P52630
RECPRGLEETWDLLS	SPATA31C2	91	B4DYI2
VIDERTDVWSLGCVL	STK16	211	O75716
DCEWLLVSERGSRLE	TLL1	916	O43897
EWTECRVDPLLSQQD	THSD7A	431	Q9UPZ6
RDWDDFGVTERLPCV	TMEM132E	151	Q6IEE7
SSQPELLDVSWLIEC	DNTT	96	P04053
EQIVDTLPDRGRSCW	ALOX5	586	P09917
PRESDWDESCLGDRL	MAB21L1	286	Q13394
CLWEASLENLEIEPD	NIN	1346	Q8N4C6
ELDPPWLERVLEACA	ABCC6	716	O95255
AVECCPTSVELWLAL	PRPF6	426	O94906
ECPNSGILWSEAIFL	PRPF6	806	O94906
EQVDLDTCWLSERPK	LAMA1	2666	P25391
AAAERCSWLVPLVRT	NBEAL2	1656	Q6ZNJ1
ELPWVHLRDAAEFTC	SIGLEC9	306	Q9Y336
TLTECWDHDPEARLT	TGFBR2	516	P37173
RNTGDADQWCPLLET	SMARCB1	341	Q12824
ADQWCPLLETLTDAE	SMARCB1	346	Q12824
VLERIEQACDPAWSA	PELO	121	Q9BRX2
CGESPVWEEVSNSLL	RGN	16	Q15493
LCSEDDRLPVIQLWD	SEC31B	231	Q9NQW1
DVLPAGCTEWRVQTL	IL9R	391	Q01113
FAGCLPESSLQRVWD	TBC1D7	211	Q9P0N9
VASLDPIKEWLNSCD	SUPT16H	876	Q9Y5B9
SIIECTASGIWDRAP	SVEP1	1941	Q4LDE5
LTCLETGDWDVDAPS	SVEP1	2536	Q4LDE5
RRLQSCSWEDEPELT	PLA2G3	66	Q9NZ20
SCRAWVSPEELEEIQ	SPDYE2B	371	A6NHP3
IESLCPEDGHRLADW	STARD8	236	Q92502
EVFICAWNPVSDLLA	TBL1XR1	171	Q9BZK7
AWDLAVDICLSQLPT	RPTOR	381	Q8N122
ECLQDWASFLRLAIP	SLC47A1	251	Q96FL8
PERKCSDSTLWEALE	ABCC8	1441	Q09428
VHNAEPWLDECLRSV	B3GNTL1	26	Q67FW5
PWLDECLRSVLQQDF	B3GNTL1	31	Q67FW5
AESRELPVRCAGDWL	ALG2	61	Q9H553
CAALPVGALATEQWE	ANGEL1	161	Q9UNK9
GASILPLCDIVWASE	CDYL2	361	Q8N8U2
CRNDIVSARPDEWLG	CHPF	266	Q8IZ52
VSARPDEWLGRCILD	CHPF	271	Q8IZ52
LSDDSLEWRRTCPDL	CLBA1	31	Q96F83
PISVTCIADEIGARW	CLEC14A	221	Q86T13
LSARPDEWLGRCLID	CHPF2	251	Q9P2E5
CQQGEDPLDWTVSLL	SLC49A3	411	Q6UXD7
LFEILLQCSEEPDSW	SPG11	1441	Q96JI7
PLDLACRIWDVFCRD	TBC1D14	596	Q9P2M4
CLEERDWDPGLAIID	TLR8	916	Q9NR97
AIEFSLEEWECLNPA	ZNF431	41	Q8TF32
LTWPSLLVEADEQLC	USP19	196	O94966
ESELPLSWADRLSGC	TAS1R3	661	Q7RTX0
FTSEEWACLGPIQRA	ZNF197	226	O14709
LSQDEWDRLCPAQRG	ZNF250	31	P15622
ISVCERHGEQDPSLW	VPS11	706	Q9H270
LETCSAVGWAPQRLV	TSPYL2	146	Q9H2G4
VEWEPASNLIEGVCL	UNC80	2606	Q8N2C7
WGTNPRDEECERIVA	PHIP	1156	Q8WWQ0
FLDLSRNLLECVPDW	PHLPP2	506	Q6ZVD8
LLLSVSESELPCEVW	RLF	136	Q13129
EAWLCSQEPLVRSAE	SPTBN2	2026	O15020
VTREPLVLGLSCSWD	RP1L1	606	Q8IWN7
PVLWVLATACGEARV	TMEM94	331	Q12767
DDWGLPDAAVVCRQL	SSC4D	216	Q8WTU2
AECEEIPGRWITRST	NGFR	186	P08138
VLSSEWQLGPLVERC	PLCH2	31	O75038
VPECRLAEDLGNLWE	SPOPL	181	Q6IQ16
SCRAWVSPEELEEIQ	SPDYE2	371	Q495Y8
SCRAWVSPEELEEIQ	SPDYE6	371	P0CI01
IRSAGCIPSNIVWDL	SPOCD1	901	Q6ZMY3
WSLLDTPGEVVQISC	TECPR1	236	Q7Z6L1
ALEACEFWLTLAEQP	TNPO2	271	O14787
VWDALREEPLCNFRG	GEMIN5	666	Q8TEQ6
ECLTVDPLSASVWRQ	TMEM214	391	Q6NUQ4
TWLEAPARAFACAVE	YDJC	171	A8MPS7
VPCSQWDELARVLVT	NF1	1231	P21359
QCEELSDARWAELLP	RNH1	11	P13489
ETLLEPGCQLESLWV	RNH1	306	P13489
VSDGCREALAAWLAP	TMDD1	106	P0DPE3
LDRCDDAITPLLNQW	VPS45	216	Q9NRW7
EVFICAWNPVSDLLA	TBL1Y	181	Q9BQ87
IRIPTVSNDIDWDFC	TTC23L	6	Q6PF05
VCLPELGALWEIESA	nan	16	Q6ZVQ6
ALEACEFWLTLAEQP	TNPO1	281	Q92973
CAPDSLEVSTRWALD	RET	216	P07949
LQAEIEPVSAVWALC	ZFP42	36	Q96MM3
PIGEDSLCSILEELW	ZNF41	166	P51814
AVAEWLRECGFLRTP	ZKSCAN2	376	Q63HK3
CGLRPEELQHISSWE	STRCP1	1596	A6NGW2
EAESRIFWLGLIACP	TVP23B	121	Q9NYZ1
TPEERLEWSEVLSNC	TBCCD1	86	Q9NVR7
RPISCGFLWESVDIQ	LCMT2	566	O60294
VNPELTSWCITGVLD	TRIM64C	266	A6NLI5
LEAVCEFSRRWEIPA	RIPOR1	941	Q6ZS17
ACEDAWPSLQTLILR	TLR2	381	O60603
GAWRILDCGSPDIEV	TG	2041	P01266
FVDRWPLESCLEILA	ZFYVE26	1481	Q68DK2
PDCRAFIVWLANGDT	TBL2	146	Q9Y4P3
VSCDEWAFSLLPLDV	VPS33B	136	Q9H267
PGAAARWDLCIDQAV	TPCN2	36	Q8NHX9
PLWAAAAVLVECGTV	TYSND1	341	Q2T9J0
EAWCSVRDLPALQEA	TCIRG1	321	Q13488
VAGPREALSRLWELC	ZNF500	61	O60304
AATELLDWCGDPRAF	ZMIZ1	31	Q9ULJ6
VIDCSWARLDETPFG	TSR3	121	Q9UJK0
LISQLERGETPWCSV	ZNF662	21	Q6ZS27
AEVWCPEADLQDLRR	ATP6V0A2	326	Q9Y487
CIEDTWLDSLLGDPE	ZNF473	116	Q8WTR7
CSNSSLALRLWVEDP	WNK3	421	Q9BYP7
CLGPFDEWESRLRVA	AGL	136	P35573
SDGRELCLDPKENWV	CXCL8	71	P10145
TWLCRVRLPVDDSTG	SLC4A1AP	396	Q9BWU0