Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	KIF13B KIF18A KIF1A KIF1B DYNC1H1 KIFC1 KIF1C	7.76e-08	70	104	7	GO:0003777
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF13B KIF18A KIF1A KIF1B MYO3B DYNC1H1 KIFC1 KIF1C	1.88e-07	118	104	8	GO:0003774
GeneOntologyMolecularFunction	plus-end-directed microtubule motor activity	KIF18A KIF1A KIF1B KIF1C	1.57e-06	17	104	4	GO:0008574
GeneOntologyMolecularFunction	ATP-dependent activity	KIF13B KIF18A ABCB7 KIF1A KIF1B ABCC9 ABCB4 ACSL1 MYO3B ATP6V0A4 DYNC1H1 KIFC1 SLC27A2 KIF1C	3.63e-06	614	104	14	GO:0140657
GeneOntologyMolecularFunction	pristanate-CoA ligase activity	ACSL1 SLC27A2	2.69e-05	2	104	2	GO:0070251
GeneOntologyMolecularFunction	phytanate-CoA ligase activity	ACSL1 SLC27A2	2.69e-05	2	104	2	GO:0050197
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF13B DIP2B KIF18A KIF1A KIF1B DBNL IPP IFT88 MYO3B PRKAA1 ABLIM2 PLK1 KIFC1 MYBPC1 KPNB1 KIF1C NLRP5	5.07e-05	1099	104	17	GO:0008092
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF13B KIF18A ABCB7 KIF1A KIF1B ABCC9 ABCB4 DYNC1H1 KIFC1 KIF1C	1.02e-04	441	104	10	GO:0016887
GeneOntologyMolecularFunction	histone H3K27 methyltransferase activity	EZH2 EHMT1	3.98e-04	6	104	2	GO:0046976
GeneOntologyMolecularFunction	tubulin binding	KIF13B DIP2B KIF18A KIF1A KIF1B PLK1 KIFC1 KIF1C NLRP5	4.00e-04	428	104	9	GO:0015631
GeneOntologyMolecularFunction	hyaluronic acid binding	STAB2 BCAN NCAN	4.54e-04	29	104	3	GO:0005540
GeneOntologyMolecularFunction	5'-3' DNA exonuclease activity	DCLRE1A MGME1	9.44e-04	9	104	2	GO:0035312
GeneOntologyMolecularFunction	microtubule binding	KIF13B KIF18A KIF1A KIF1B PLK1 KIFC1 KIF1C	1.15e-03	308	104	7	GO:0008017
GeneOntologyMolecularFunction	arachidonate-CoA ligase activity	ACSL1 SLC27A2	1.43e-03	11	104	2	GO:0047676
GeneOntologyBiologicalProcess	retrograde neuronal dense core vesicle transport	KIF1A KIF1B KIF1C	2.39e-06	6	103	3	GO:1990049
GeneOntologyBiologicalProcess	retrograde axonal transport	KIF1A KIF1B DYNC1H1 KIF1C	5.77e-06	24	103	4	GO:0008090
GeneOntologyBiologicalProcess	anterograde neuronal dense core vesicle transport	KIF1A KIF1B KIF1C	6.65e-06	8	103	3	GO:1990048
GeneOntologyBiologicalProcess	cell surface receptor protein tyrosine kinase signaling pathway	NPR2 IL31RA ANGPT1 SLC31A1 EFS INS GFRA1 SHKBP1 KL IFT88 EPHA2 PRKAA1 INS-IGF2 EPHA7	2.06e-05	747	103	14	GO:0007169
GeneOntologyBiologicalProcess	dense core granule cytoskeletal transport	KIF1A KIF1B KIF1C	2.57e-05	12	103	3	GO:0099519
GeneOntologyBiologicalProcess	dense core granule transport	KIF1A KIF1B KIF1C	4.23e-05	14	103	3	GO:1901950
GeneOntologyBiologicalProcess	negative regulation of NAD(P)H oxidase activity	INS INS-IGF2	7.38e-05	3	103	2	GO:0033861
GeneOntologyBiologicalProcess	fatty acid homeostasis	INS PRKAA1 INS-IGF2	9.34e-05	18	103	3	GO:0055089
GeneOntologyBiologicalProcess	negative regulation of glycogen catabolic process	INS INS-IGF2	1.47e-04	4	103	2	GO:0045818
GeneOntologyBiologicalProcess	positive regulation of nitric oxide mediated signal transduction	INS INS-IGF2	1.47e-04	4	103	2	GO:0010750
GeneOntologyBiologicalProcess	purine ribonucleotide metabolic process	NPR2 INS ABCC9 EIF6 ACSL1 EPHA2 PRKAA1 INS-IGF2 SDHD SLC27A2	2.44e-04	512	103	10	GO:0009150
GeneOntologyBiologicalProcess	positive regulation of lipid kinase activity	INS INS-IGF2	2.45e-04	5	103	2	GO:0090218
GeneOntologyBiologicalProcess	establishment of spindle localization	PLK1 DYNC1H1 KPNB1 NLRP5	2.62e-04	62	103	4	GO:0051293
GeneOntologyBiologicalProcess	regulation of nucleotide catabolic process	INS EIF6 PRKAA1 INS-IGF2	2.79e-04	63	103	4	GO:0030811
GeneOntologyBiologicalProcess	regulation of purine nucleotide catabolic process	INS EIF6 PRKAA1 INS-IGF2	2.79e-04	63	103	4	GO:0033121
GeneOntologyBiologicalProcess	regulation of glycolytic process	INS EIF6 PRKAA1 INS-IGF2	2.79e-04	63	103	4	GO:0006110
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	KIF13B DIP2B CARMIL2 KIF1A INS DBNL EZH2 PARP6 IFT88 EPHA2 MYO3B INS-IGF2 EPHA7	3.00e-04	846	103	13	GO:0120035
GeneOntologyBiologicalProcess	regulation of postsynapse organization	KIF1A INS DBNL NCAN INS-IGF2 EPHA7	3.34e-04	185	103	6	GO:0099175
GeneOntologyBiologicalProcess	ribonucleotide metabolic process	NPR2 INS ABCC9 EIF6 ACSL1 EPHA2 PRKAA1 INS-IGF2 SDHD SLC27A2	3.35e-04	533	103	10	GO:0009259
GeneOntologyBiologicalProcess	regulation of cell development	DIP2B NPR2 CARMIL2 INS DBNL BCAN SKI EZH2 EIF6 PARP6 NCAN TMEM131L RECK INS-IGF2 EPHA7	3.45e-04	1095	103	15	GO:0060284
GeneOntologyBiologicalProcess	spindle localization	PLK1 DYNC1H1 KPNB1 NLRP5	3.53e-04	67	103	4	GO:0051653
GeneOntologyBiologicalProcess	dense core granule localization	KIF1A KIF1B KIF1C	3.62e-04	28	103	3	GO:0032253
GeneOntologyBiologicalProcess	regulation of cell projection organization	KIF13B DIP2B CARMIL2 KIF1A INS DBNL EZH2 PARP6 IFT88 EPHA2 MYO3B INS-IGF2 EPHA7	3.63e-04	863	103	13	GO:0031344
GeneOntologyBiologicalProcess	negative regulation of respiratory burst involved in inflammatory response	INS INS-IGF2	3.66e-04	6	103	2	GO:0060266
GeneOntologyBiologicalProcess	regulation of NAD(P)H oxidase activity	INS INS-IGF2	3.66e-04	6	103	2	GO:0033860
GeneOntologyBiologicalProcess	ribose phosphate metabolic process	NPR2 INS ABCC9 EIF6 ACSL1 EPHA2 PRKAA1 INS-IGF2 SDHD SLC27A2	3.71e-04	540	103	10	GO:0019693
GeneOntologyBiologicalProcess	negative regulation of reactive oxygen species biosynthetic process	ABCB7 INS INS-IGF2	4.02e-04	29	103	3	GO:1903427
GeneOntologyBiologicalProcess	positive regulation of glycolytic process	INS PRKAA1 INS-IGF2	4.02e-04	29	103	3	GO:0045821
GeneOntologyBiologicalProcess	positive regulation of nucleotide catabolic process	INS PRKAA1 INS-IGF2	4.02e-04	29	103	3	GO:0030813
GeneOntologyBiologicalProcess	positive regulation of purine nucleotide catabolic process	INS PRKAA1 INS-IGF2	4.02e-04	29	103	3	GO:0033123
GeneOntologyBiologicalProcess	establishment of organelle localization	KIF18A KIF1A KIF1B EIF6 PLK1 DYNC1H1 KIFC1 KPNB1 KIF1C NLRP5	4.05e-04	546	103	10	GO:0051656
GeneOntologyBiologicalProcess	positive regulation of dendritic spine maintenance	INS INS-IGF2	5.10e-04	7	103	2	GO:1902952
GeneOntologyBiologicalProcess	positive regulation of peptidyl-lysine acetylation	DIP2B PRKAA1	5.10e-04	7	103	2	GO:2000758
GeneOntologyBiologicalProcess	axonal transport	KIF1A KIF1B DYNC1H1 KIF1C	5.43e-04	75	103	4	GO:0098930
GeneOntologyBiologicalProcess	negative regulation of lipid catabolic process	INS PRKAA1 INS-IGF2	6.47e-04	34	103	3	GO:0050995
GeneOntologyBiologicalProcess	secretory granule localization	KIF1A KIF1B KIF1C	6.47e-04	34	103	3	GO:0032252
GeneOntologyBiologicalProcess	lipid homeostasis	INS LYST ACOX2 ABCB4 PRKAA1 INS-IGF2	6.69e-04	211	103	6	GO:0055088
GeneOntologyBiologicalProcess	negative regulation of respiratory burst	INS INS-IGF2	6.78e-04	8	103	2	GO:0060268
GeneOntologyBiologicalProcess	reactive oxygen species biosynthetic process	ABCB7 INS ABCC9 INS-IGF2	6.93e-04	80	103	4	GO:1903409
GeneOntologyBiologicalProcess	very long-chain fatty acid metabolic process	ACOX2 ACSL1 SLC27A2	7.05e-04	35	103	3	GO:0000038
GeneOntologyBiologicalProcess	acute inflammatory response	IL31RA INS SAA4 ANO6 INS-IGF2	7.58e-04	143	103	5	GO:0002526
GeneOntologyBiologicalProcess	regulation of carbohydrate catabolic process	INS EIF6 PRKAA1 INS-IGF2	7.61e-04	82	103	4	GO:0043470
GeneOntologyBiologicalProcess	microtubule-based process	KIF13B KIF18A KIF1A KIF1B CHEK1 LYST IFT88 PRKAA1 PLK1 DYNC1H1 KIFC1 KPNB1 KIF1C NLRP5	7.76e-04	1058	103	14	GO:0007017
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	NPR2 IL31RA ANGPT1 SLC31A1 EFS INS SKI GFRA1 SHKBP1 KL IFT88 EPHA2 PRKAA1 INS-IGF2 EPHA7	7.91e-04	1186	103	15	GO:0007167
GeneOntologyBiologicalProcess	microtubule-based movement	KIF13B KIF18A KIF1A KIF1B IFT88 DYNC1H1 KIFC1 KPNB1 KIF1C	8.14e-04	493	103	9	GO:0007018
GeneOntologyCellularComponent	kinesin complex	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.54e-07	49	104	6	GO:0005871
GeneOntologyCellularComponent	microtubule associated complex	KIF13B KIF18A KIF1A KIF1B DYNC1H1 KIFC1 KIF1C	1.60e-05	161	104	7	GO:0005875
GeneOntologyCellularComponent	axon cytoplasm	KIF1A KIF1B DYNC1H1 KIF1C	3.69e-04	68	104	4	GO:1904115
Domain	Kinesin_assoc	KIF13B KIF1A KIF1B KIF1C	1.30e-08	6	103	4	PF16183
Domain	Kinesin_assoc	KIF13B KIF1A KIF1B KIF1C	1.30e-08	6	103	4	IPR032405
Domain	Kinesin_motor_CS	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	9.34e-08	41	103	6	IPR019821
Domain	Kinesin-like_fam	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.25e-07	43	103	6	IPR027640
Domain	KINESIN_MOTOR_1	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.45e-07	44	103	6	PS00411
Domain	-	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.45e-07	44	103	6	3.40.850.10
Domain	Kinesin_motor_dom	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.45e-07	44	103	6	IPR001752
Domain	Kinesin	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.45e-07	44	103	6	PF00225
Domain	KINESIN_MOTOR_2	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.45e-07	44	103	6	PS50067
Domain	KISc	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.45e-07	44	103	6	SM00129
Domain	Kinesin-like_KIF1-typ	KIF13B KIF1A KIF1B	6.49e-07	4	103	3	IPR022140
Domain	KIF1B	KIF13B KIF1A KIF1B	6.49e-07	4	103	3	PF12423
Domain	DUF3694	KIF13B KIF1A KIF1B	3.22e-06	6	103	3	PF12473
Domain	Kinesin-like	KIF13B KIF1A KIF1B	3.22e-06	6	103	3	IPR022164
Domain	FHA	KIF13B KIF1A KIF1B KIF1C	1.61e-05	28	103	4	SM00240
Domain	FHA_DOMAIN	KIF13B KIF1A KIF1B KIF1C	2.45e-05	31	103	4	PS50006
Domain	FHA	KIF13B KIF1A KIF1B KIF1C	2.45e-05	31	103	4	PF00498
Domain	LINK	STAB2 BCAN NCAN	4.48e-05	13	103	3	SM00445
Domain	Link_dom	STAB2 BCAN NCAN	4.48e-05	13	103	3	IPR000538
Domain	Xlink	STAB2 BCAN NCAN	4.48e-05	13	103	3	PF00193
Domain	LINK_1	STAB2 BCAN NCAN	4.48e-05	13	103	3	PS01241
Domain	LINK_2	STAB2 BCAN NCAN	4.48e-05	13	103	3	PS50963
Domain	FHA_dom	KIF13B KIF1A KIF1B KIF1C	4.49e-05	36	103	4	IPR000253
Domain	-	KIF13B KIF1A KIF1B KIF1C	4.49e-05	36	103	4	2.60.200.20
Domain	SMAD_FHA_domain	KIF13B KIF1A KIF1B KIF1C	1.93e-04	52	103	4	IPR008984
Domain	ABC_membrane	ABCB7 ABCC9 ABCB4	3.03e-04	24	103	3	PF00664
Domain	ABC_TM1F	ABCB7 ABCC9 ABCB4	4.83e-04	28	103	3	PS50929
Domain	ABC1_TM_dom	ABCB7 ABCC9 ABCB4	4.83e-04	28	103	3	IPR011527
Domain	AMP-binding	DIP2B ACSL1 SLC27A2	5.93e-04	30	103	3	PF00501
Domain	AMP-dep_Synth/Lig	DIP2B ACSL1 SLC27A2	5.93e-04	30	103	3	IPR000873
Domain	EGF-like_CS	STAB2 BCAN EYS EPHA2 NCAN CNTNAP4 EPHA7	6.08e-04	261	103	7	IPR013032
Domain	EGF_2	STAB2 BCAN EYS EPHA2 NCAN CNTNAP4 EPHA7	6.65e-04	265	103	7	PS01186
Domain	EGF	STAB2 BCAN EYS NCAN CNTNAP4	6.66e-04	126	103	5	PF00008
Domain	P-loop_NTPase	KIF13B KIF18A ABCB7 KIF1A KIF1B ABCC9 ABCB4 MYO3B WSCD2 DYNC1H1 KIFC1 KIF1C NLRP5	7.78e-04	848	103	13	IPR027417
Domain	Gal_Oxidase_b-propeller	IPP KLHL11 KLHDC10	8.61e-04	34	103	3	IPR015916
Domain	-	INS INS-IGF2	1.06e-03	9	103	2	1.10.100.10
Domain	Insulin	INS INS-IGF2	1.32e-03	10	103	2	PF00049
Domain	ABC_transporter_CS	ABCB7 ABCC9 ABCB4	1.60e-03	42	103	3	IPR017871
Domain	Insulin	INS INS-IGF2	1.60e-03	11	103	2	IPR004825
Domain	Insulin-like	INS INS-IGF2	1.60e-03	11	103	2	IPR016179
Domain	IlGF	INS INS-IGF2	1.60e-03	11	103	2	SM00078
Domain	Calpain_III	CAPN9 CAPN5	1.92e-03	12	103	2	IPR022683
Domain	calpain_III	CAPN9 CAPN5	1.92e-03	12	103	2	SM00720
Domain	C2_III	CAPN9 CAPN5	1.92e-03	12	103	2	IPR033883
Domain	fn3	IL31RA SPEG EPHA2 MYBPC1 EPHA7	2.04e-03	162	103	5	PF00041
Domain	Calpain_domain_III	CAPN9 CAPN5	2.26e-03	13	103	2	IPR022682
Domain	Calpain_III	CAPN9 CAPN5	2.26e-03	13	103	2	PF01067
Domain	ABC_tran	ABCB7 ABCC9 ABCB4	2.35e-03	48	103	3	PF00005
Domain	-	IPP KLHL11 KLHDC10	2.35e-03	48	103	3	2.120.10.80
Domain	ABC_TRANSPORTER_2	ABCB7 ABCC9 ABCB4	2.35e-03	48	103	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCB7 ABCC9 ABCB4	2.50e-03	49	103	3	PS00211
Domain	RECEPTOR_TYR_KIN_V_2	EPHA2 EPHA7	2.62e-03	14	103	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA2 EPHA7	2.62e-03	14	103	2	PS00790
Domain	Eph_TM	EPHA2 EPHA7	2.62e-03	14	103	2	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHA2 EPHA7	2.62e-03	14	103	2	IPR001426
Domain	Calpain_cysteine_protease	CAPN9 CAPN5	2.62e-03	14	103	2	IPR022684
Domain	EPH_lbd	EPHA2 EPHA7	2.62e-03	14	103	2	SM00615
Domain	Ephrin_lbd	EPHA2 EPHA7	2.62e-03	14	103	2	PF01404
Domain	EphA2_TM	EPHA2 EPHA7	2.62e-03	14	103	2	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHA2 EPHA7	2.62e-03	14	103	2	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHA2 EPHA7	2.62e-03	14	103	2	IPR001090
Domain	EPH_LBD	EPHA2 EPHA7	2.62e-03	14	103	2	PS51550
Domain	ABC_transporter-like	ABCB7 ABCC9 ABCB4	2.65e-03	50	103	3	IPR003439
Domain	Sushi	BCAN CR2 NCAN	2.96e-03	52	103	3	PF00084
Domain	CysPc	CAPN9 CAPN5	3.02e-03	15	103	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN9 CAPN5	3.02e-03	15	103	2	IPR001300
Domain	Peptidase_C2	CAPN9 CAPN5	3.02e-03	15	103	2	PF00648
Domain	CALPAIN_CAT	CAPN9 CAPN5	3.02e-03	15	103	2	PS50203
Domain	CCP	BCAN CR2 NCAN	3.29e-03	54	103	3	SM00032
Domain	Kelch-typ_b-propeller	IPP KLHL11 KLHDC10	3.47e-03	55	103	3	IPR015915
Domain	FN3	IL31RA SPEG EPHA2 MYBPC1 EPHA7	3.62e-03	185	103	5	SM00060
Domain	SUSHI	BCAN CR2 NCAN	3.65e-03	56	103	3	PS50923
Domain	Sushi_SCR_CCP_dom	BCAN CR2 NCAN	3.84e-03	57	103	3	IPR000436
Domain	Kelch	IPP KLHL11 KLHDC10	4.03e-03	58	103	3	SM00612
Domain	FN3	IL31RA SPEG EPHA2 MYBPC1 EPHA7	4.92e-03	199	103	5	PS50853
Domain	Protein_kinase_ATP_BS	SPEG CHEK1 EPHA2 MYO3B PRKAA1 PLK1 EPHA7	5.02e-03	379	103	7	IPR017441
Pathway	REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	KIF13B KIF18A KIF1A KIF1B COPB2 DYNC1H1 KIFC1 KIF1C	5.51e-07	131	77	8	MM15497
Pathway	REACTOME_KINESINS	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	6.34e-07	57	77	6	MM15714
Pathway	REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	KIF13B KIF18A KIF1A KIF1B COPB2 DYNC1H1 KIFC1 KIF1C	6.55e-07	134	77	8	M27751
Pathway	REACTOME_KINESINS	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	9.53e-07	61	77	6	M977
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	KIF13B KIF18A KIF1A KIF1B COPB2 KIFC1 KIF1C	1.02e-06	98	77	7	MM15352
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	KIF13B KIF18A KIF1A KIF1B COPB2 KIFC1 KIF1C	1.17e-06	100	77	7	M27650
Pathway	REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC	KIF13B KIF18A KIF1A KIF1B COPB2 DYNC1H1 KIFC1 KIF1C	8.60e-06	189	77	8	MM15356
Pathway	REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC	KIF13B KIF18A KIF1A KIF1B COPB2 DYNC1H1 KIFC1 KIF1C	1.45e-05	203	77	8	M27654
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	4.02e-05	116	77	6	MM15715
Pathway	REACTOME_CS_DS_DEGRADATION	BCAN IDUA NCAN	5.46e-05	14	77	3	M651
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	3.29e-04	170	77	6	M941
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	CHEK1 EZH2 EHMT1	3.31e-04	25	77	3	MM15546
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	ACOX2 ABCB4 SLC27A2	5.17e-04	29	77	3	M45551
Pathway	REACTOME_INSULIN_RECEPTOR_RECYCLING	INS ATP6V0A4 INS-IGF2	6.31e-04	31	77	3	MM15467
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	KIF13B KIF18A STAB2 KIF1A INS KIF1B COPB2 INS-IGF2 DYNC1H1 KIFC1 KIF1C	7.20e-04	645	77	11	MM15232
Pathway	REACTOME_SIGNALING_BY_INSULIN_RECEPTOR	INS KL ATP6V0A4 INS-IGF2	7.84e-04	76	77	4	MM15442
Pathway	REACTOME_DEFECTIVE_CHST14_CAUSES_EDS_MUSCULOCONTRACTURAL_TYPE	BCAN NCAN	8.07e-04	8	77	2	M27260
Pathway	REACTOME_DEFECTIVE_CHSY1_CAUSES_TPBS	BCAN NCAN	8.07e-04	8	77	2	M27261
Pathway	REACTOME_DEFECTIVE_CHST3_CAUSES_SEDCJD	BCAN NCAN	8.07e-04	8	77	2	M27259
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	CHEK1 EZH2 EHMT1	8.30e-04	34	77	3	M27826
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.33e-09	37	104	6	11416179
Pubmed	HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.	KIF1A KIF1B DYNC1H1 KIF1C	5.23e-09	8	104	4	25818806
Pubmed	Primary cilia control glucose homeostasis via islet paracrine interactions.	INS IFT88 INS-IGF2	2.60e-08	3	104	3	32253320
Pubmed	In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport.	KIF1A KIF1B KIF1C	2.60e-08	3	104	3	23404705
Pubmed	Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.	INS KL INS-IGF2	2.60e-08	3	104	3	26586006
Pubmed	Insulin restores UCP3 activity and decreases energy surfeit to alleviate lipotoxicity in skeletal muscle.	INS PRKAA1 INS-IGF2	1.04e-07	4	104	3	29039450
Pubmed	Regulation of dendritic cell function by insulin/IGF-1/PI3K/Akt signaling through klotho expression.	INS KL INS-IGF2	1.04e-07	4	104	3	27808000
Pubmed	AMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys.	INS PRKAA1 INS-IGF2	1.04e-07	4	104	3	25428125
Pubmed	Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells.	INS KL INS-IGF2	1.04e-07	4	104	3	22597535
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	CAPN9 OLFML2B SRD5A2 CR2 PTH1R NUP155 PRKAA1 TMEM131L USP39 DYNC1H1	1.41e-07	361	104	10	18976975
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DIP2B CLGN KIF1A DUSP7 COPB2 CHEK1 SHKBP1 ACSL1 NUP155 EPHA2 PRKAA1 TMEM131L PLK1 PTPN20 KPNB1	2.15e-07	974	104	15	28675297
Pubmed	Dual Effect of Raptor on Neonatal β-Cell Proliferation and Identity Maintenance.	INS EZH2 PLK1 INS-IGF2	2.24e-07	18	104	4	31345937
Pubmed	LKB1 and AMPK differentially regulate pancreatic β-cell identity.	INS PRKAA1 INS-IGF2	2.59e-07	5	104	3	25070369
Pubmed	Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.	INS EZH2 INS-IGF2	5.16e-07	6	104	3	25107471
Pubmed	Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation.	INS PLK1 INS-IGF2	5.16e-07	6	104	3	28286049
Pubmed	MiR-184 expression is regulated by AMPK in pancreatic islets.	INS PRKAA1 INS-IGF2	9.01e-07	7	104	3	29269398
Pubmed	A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion.	INS PRKAA1 INS-IGF2	9.01e-07	7	104	3	32375022
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF13B KIF1A KIF1B KIF1C	9.09e-07	25	104	4	9275178
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	STAB2 ANGPT1 SKI TMEM255B GFRA1 EYS RECK	2.40e-06	199	104	7	23382691
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	KIF18A SLC31A1 CHEK1 CR2 GFRA1 SHKBP1 EPHA2 PLK1	4.16e-06	307	104	8	37499664
Pubmed	Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function.	ANGPT1 INS INS-IGF2	5.60e-06	12	104	3	17065333
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ABCB7 ACSL1 NUP155 SYNGR2 PRKAA1 EHMT1 ASCC2 PLK1 DYNC1H1 KPNB1	7.28e-06	560	104	10	35241646
Pubmed	SGLT1/2 inhibition improves glycemic control and multi-organ protection in type 1 diabetes.	INS INS-IGF2	8.86e-06	2	104	2	37520739
Pubmed	Neuritic dystrophy and neuronopathy in Akita (Ins2(Akita)) diabetic mouse sympathetic ganglia.	INS INS-IGF2	8.86e-06	2	104	2	19111542
Pubmed	Ectopic expression of Plk1 leads to activation of the spindle checkpoint.	CHEK1 PLK1	8.86e-06	2	104	2	17102638
Pubmed	Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes.	INS INS-IGF2	8.86e-06	2	104	2	26733677
Pubmed	Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy.	INS INS-IGF2	8.86e-06	2	104	2	37628852
Pubmed	Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling.	INS INS-IGF2	8.86e-06	2	104	2	27335233
Pubmed	Expression of preproinsulin-2 gene shapes the immune response to preproinsulin in normal mice.	INS INS-IGF2	8.86e-06	2	104	2	14688305
Pubmed	Aberrant Activation of Cell-Cycle-Related Kinases and the Potential Therapeutic Impact of PLK1 or CHEK1 Inhibition in Uterine Leiomyosarcoma.	CHEK1 PLK1	8.86e-06	2	104	2	35302600
Pubmed	Bioinformatics Analysis of Weighted Genes in Diabetic Retinopathy.	INS INS-IGF2	8.86e-06	2	104	2	30480744
Pubmed	The implications of hyperoxia, type 1 diabetes and sex on cardiovascular physiology in mice.	INS INS-IGF2	8.86e-06	2	104	2	34845324
Pubmed	Genetic control of insulin receptors.	INS INS-IGF2	8.86e-06	2	104	2	7031649
Pubmed	Thymic expression of mutated B16:A preproinsulin messenger RNA does not reverse acceleration of NOD diabetes associated with insulin 2 (thymic expressed insulin) knockout.	INS INS-IGF2	8.86e-06	2	104	2	16289958
Pubmed	Insulin rescues impaired spermatogenesis via the hypothalamic-pituitary-gonadal axis in Akita diabetic mice and restores male fertility.	INS INS-IGF2	8.86e-06	2	104	2	22522616
Pubmed	Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq.	INS INS-IGF2	8.86e-06	2	104	2	27855634
Pubmed	Metabolomics Reveals a Key Role for Fumarate in Mediating the Effects of NADPH Oxidase 4 in Diabetic Kidney Disease.	INS INS-IGF2	8.86e-06	2	104	2	26203118
Pubmed	Maternal Chromium Restriction Leads to Glucose Metabolism Imbalance in Mice Offspring through Insulin Signaling and Wnt Signaling Pathways.	INS INS-IGF2	8.86e-06	2	104	2	27782077
Pubmed	Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells.	INS INS-IGF2	8.86e-06	2	104	2	29995913
Pubmed	Maternal diabetes adversely affects preovulatory oocyte maturation, development, and granulosa cell apoptosis.	INS INS-IGF2	8.86e-06	2	104	2	15718275
Pubmed	Insulin-Deficient Mouse β-Cells Do Not Fully Mature but Can Be Remedied Through Insulin Replacement by Islet Transplantation.	INS INS-IGF2	8.86e-06	2	104	2	29029025
Pubmed	Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.	INS INS-IGF2	8.86e-06	2	104	2	20948967
Pubmed	Prevalence and Clinical Characteristics of PDX1 Variant Induced Diabetes in Chinese Early-Onset Type 2 Diabetes.	INS INS-IGF2	8.86e-06	2	104	2	37279936
Pubmed	An imprinted GFP insertion reveals long-range epigenetic regulation in embryonic lineages.	INS INS-IGF2	8.86e-06	2	104	2	19778534
Pubmed	Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.	INS INS-IGF2	8.86e-06	2	104	2	26696124
Pubmed	Compensatory hyperinsulinemia in high-fat diet-induced obese mice is associated with enhanced insulin translation in islets.	INS INS-IGF2	8.86e-06	2	104	2	25686499
Pubmed	Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring.	INS INS-IGF2	8.86e-06	2	104	2	23209676
Pubmed	Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility.	INS INS-IGF2	8.86e-06	2	104	2	27055260
Pubmed	Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function.	INS INS-IGF2	8.86e-06	2	104	2	19801494
Pubmed	Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice.	INS INS-IGF2	8.86e-06	2	104	2	33667544
Pubmed	Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2.	INS INS-IGF2	8.86e-06	2	104	2	7729600
Pubmed	Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes.	INS INS-IGF2	8.86e-06	2	104	2	22015457
Pubmed	Impact of genetic background on nephropathy in diabetic mice.	INS INS-IGF2	8.86e-06	2	104	2	16118394
Pubmed	High glucose and diabetes modulate cellular proteasome function: Implications in the pathogenesis of diabetes complications.	INS INS-IGF2	8.86e-06	2	104	2	23391566
Pubmed	A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy.	INS INS-IGF2	8.86e-06	2	104	2	17151334
Pubmed	Dynamic Ins2 Gene Activity Defines β-Cell Maturity States.	INS INS-IGF2	8.86e-06	2	104	2	36170671
Pubmed	Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages.	INS INS-IGF2	8.86e-06	2	104	2	23894189
Pubmed	Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage.	INS INS-IGF2	8.86e-06	2	104	2	29439088
Pubmed	Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice.	INS INS-IGF2	8.86e-06	2	104	2	22449801
Pubmed	Insulin2 gene (Ins2) transcription by NOD bone marrow-derived cells does not influence autoimmune diabetes development in NOD-Ins2 knockout mice.	INS INS-IGF2	8.86e-06	2	104	2	19874548
Pubmed	Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes.	INS INS-IGF2	8.86e-06	2	104	2	16936198
Pubmed	Antagonising Wnt/β-catenin signalling ameliorates lens-capsulotomy-induced retinal degeneration in a mouse model of diabetes.	INS INS-IGF2	8.86e-06	2	104	2	30019207
Pubmed	Imprinting at the mouse Ins2 locus: evidence for cis- and trans-allelic interactions.	INS INS-IGF2	8.86e-06	2	104	2	9465295
Pubmed	The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic beta-cells.	INS INS-IGF2	8.86e-06	2	104	2	15972000
Pubmed	Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing.	INS INS-IGF2	8.86e-06	2	104	2	28837672
Pubmed	Inducing Specific Immune Tolerance to Prevent Type 1 Diabetes in NOD Mice.	INS INS-IGF2	8.86e-06	2	104	2	26784909
Pubmed	Novel splice variant of mouse insulin2 mRNA: implications for insulin expression.	INS INS-IGF2	8.86e-06	2	104	2	20153322
Pubmed	Transgenic Expression of miR-133a in the Diabetic Akita Heart Prevents Cardiac Remodeling and Cardiomyopathy.	INS INS-IGF2	8.86e-06	2	104	2	31069235
Pubmed	High fat diet induces brain insulin resistance and cognitive impairment in mice.	INS INS-IGF2	8.86e-06	2	104	2	27771511
Pubmed	Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice.	INS INS-IGF2	8.86e-06	2	104	2	26552047
Pubmed	Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes.	INS INS-IGF2	8.86e-06	2	104	2	34462258
Pubmed	Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.	INS INS-IGF2	8.86e-06	2	104	2	20825366
Pubmed	Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion.	INS INS-IGF2	8.86e-06	2	104	2	22065673
Pubmed	Increased superoxide contributes to enhancement of vascular contraction in Ins2(Akita) diabetic mice, an autosomal dominant mutant model.	INS INS-IGF2	8.86e-06	2	104	2	18788099
Pubmed	Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.	INS INS-IGF2	8.86e-06	2	104	2	15889095
Pubmed	Interaction of glucagon-like peptide-I (7-37) and somatostatin-14 on signal transduction and proinsulin gene expression in beta TC-1 cells.	INS INS-IGF2	8.86e-06	2	104	2	7911222
Pubmed	Complications of IgA nephropathy in a non-insulin-dependent diabetes model, the Akita mouse.	INS INS-IGF2	8.86e-06	2	104	2	12630555
Pubmed	Retinal blood flow abnormalities following six months of hyperglycemia in the Ins2(Akita) mouse.	INS INS-IGF2	8.86e-06	2	104	2	22440813
Pubmed	Dual inhibition of SGLT2 and DPP-4 promotes natriuresis and improves glomerular hemodynamic abnormalities in KK/Ta-Ins2Akita mice with progressive diabetic kidney disease.	INS INS-IGF2	8.86e-06	2	104	2	36265286
Pubmed	β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes.	INS INS-IGF2	8.86e-06	2	104	2	36048448
Pubmed	Proinsulin atypical maturation and disposal induces extensive defects in mouse Ins2+/Akita β-cells.	INS INS-IGF2	8.86e-06	2	104	2	22509386
Pubmed	The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.	KIF1A KIF1B	8.86e-06	2	104	2	7539720
Pubmed	New mouse model to study islet transplantation in insulin-dependent diabetes mellitus.	INS INS-IGF2	8.86e-06	2	104	2	11981430
Pubmed	β-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs.	INS INS-IGF2	8.86e-06	2	104	2	34246804
Pubmed	Both spontaneous Ins2(+/-) and streptozotocin-induced type I diabetes cause bone loss in young mice.	INS INS-IGF2	8.86e-06	2	104	2	22886636
Pubmed	Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.	INS INS-IGF2	8.86e-06	2	104	2	17911348
Pubmed	Genetic analysis of a new mouse model for non-insulin-dependent diabetes.	INS INS-IGF2	8.86e-06	2	104	2	11414755
Pubmed	Estrogens Promote Misfolded Proinsulin Degradation to Protect Insulin Production and Delay Diabetes.	INS INS-IGF2	8.86e-06	2	104	2	29972779
Pubmed	Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling.	INS INS-IGF2	8.86e-06	2	104	2	29970188
Pubmed	Diabetic Stroke Severity: Epigenetic Remodeling and Neuronal, Glial, and Vascular Dysfunction.	INS INS-IGF2	8.86e-06	2	104	2	26470785
Pubmed	Quantification of insulin gene expression during development of pancreatic islet cells.	INS INS-IGF2	8.86e-06	2	104	2	19812524
Pubmed	Tuberculosis susceptibility of diabetic mice.	INS INS-IGF2	8.86e-06	2	104	2	17585110
Pubmed	A new model of insulin-deficient diabetes: male NOD mice with a single copy of Ins1 and no Ins2.	INS INS-IGF2	8.86e-06	2	104	2	16612590
Pubmed	Inhibition of nitric oxide production reverses diabetes-induced Kupffer cell activation and Klebsiella pneumonia liver translocation.	INS INS-IGF2	8.86e-06	2	104	2	28493939
Pubmed	Dealing with employment issues.	INS INS-IGF2	8.86e-06	2	104	2	20043456
Pubmed	Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes.	INS INS-IGF2	8.86e-06	2	104	2	32198206
Pubmed	RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon.	INS INS-IGF2	8.86e-06	2	104	2	2427930
Pubmed	Differential Impact of Chronic Hyperglycemia on Humoral Versus Cellular Primary Alloimmunity.	INS INS-IGF2	8.86e-06	2	104	2	28069641
Pubmed	Macrophages and neutrophils are necessary for ER stress-induced β cell loss.	INS INS-IGF2	8.86e-06	2	104	2	36001973
Pubmed	Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.	INS INS-IGF2	8.86e-06	2	104	2	29211719
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF13B KIF18A KIF1A KIF1B KIFC1 KIF1C	1.72e-08	46	67	6	622
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	BCAN NCAN	8.08e-05	4	67	2	574
GeneFamily	ATP binding cassette subfamily B	ABCB7 ABCB4	7.28e-04	11	67	2	806
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA2 EPHA7	1.20e-03	14	67	2	1095
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	BCAN CR2 NCAN	1.23e-03	57	67	3	1179
GeneFamily	C2 domain containing\|Calpains	CAPN9 CAPN5	1.38e-03	15	67	2	975
GeneFamily	Fibronectin type III domain containing	IL31RA EPHA2 MYBPC1 EPHA7	2.94e-03	160	67	4	555
GeneFamily	Acyl-CoA synthetase family	ACSL1 SLC27A2	4.15e-03	26	67	2	40
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	EZH2 EHMT1	7.03e-03	34	67	2	487
Coexpression	CAIRO_HEPATOBLASTOMA_DN	STAB2 SRD5A2 PTH1R ACSL1 SAA4 EPHA2 TMEM131L SLC27A2	1.16e-05	267	104	8	M13449
Coexpression	GSE17721_CTRL_VS_LPS_0.5H_BMDC_UP	DIP2B ABCB7 KIF1A IPP IFT88 ASCC2 MFSD5	1.54e-05	200	104	7	M3679
ToppCell	droplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 KIF18A CHEK1 TCHH DCLRE1A PLK1 KIFC1	2.24e-07	180	104	7	43fd5c498a87bb078d101298b472656f3294686a
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 KIF18A CHEK1 TCHH DCLRE1A PLK1 KIFC1	2.50e-07	183	104	7	e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 CHEK1 TMEM255B EPHA2 ABLIM2 RECK KIFC1	2.79e-07	186	104	7	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CHEK1 EZH2 PARP6 PLK1 KIFC1	3.29e-06	173	104	6	f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF18A CHEK1 EZH2 KLHL11 PLK1 KIFC1	3.63e-06	176	104	6	b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Pde1c_(Striatum,_dSPNs,_Pde1c_+)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	INS SAA4 MYO3B MS4A5	4.85e-06	48	104	4	2f7193765a580767f37ffb1369f3c99dedf445f0
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Pde1c_(Striatum,_dSPNs,_Pde1c_+)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	INS SAA4 MYO3B MS4A5	4.85e-06	48	104	4	411d57f7aceb7ed8a96d334112a0694c416c85f2
ToppCell	(3)_Chondrocytes-(30)_Chondro\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	STAB2 ANGPT1 ABCC9 GFRA1 ATP6V0A4 RECK	6.54e-06	195	104	6	f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCell	mild-Lymphocytic-Prol._cells\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	6.74e-06	196	104	6	b1d9866d5dfaefdb8bedaf01a750d97987acb3d1
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	6.94e-06	197	104	6	4b13335a43b9d6abc8e542e72440da7feb82fbe6
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF13B CLGN BCAN GFRA1 PLK1 KIFC1	6.94e-06	197	104	6	cd7e34318b4ae72b7b312fda8cc0e041c2ac4ab5
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	6.94e-06	197	104	6	21861d8b389fafbdb7c3499684c9b6deee3dbd5e
ToppCell	distal-mesenchymal-Vascular_Smooth_Muscle-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANGPT1 EFS OLFML2B PPP1R12B ABCC9 PTH1R	6.94e-06	197	104	6	da653dc7d216e202f390e5ab0245f243e3ed213b
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	6.94e-06	197	104	6	ffb004c37cdd26cb7cdcd80f769a2eded65416dc
ToppCell	distal-3-mesenchymal-Vascular_Smooth_Muscle\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANGPT1 OLFML2B PPP1R12B ABCC9 PTH1R GFRA1	7.14e-06	198	104	6	37ce7b485ffb207e75afd1b576b486c6d59fc136
ToppCell	distal-mesenchymal-Vascular_Smooth_Muscle\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANGPT1 OLFML2B PPP1R12B ABCC9 PTH1R GFRA1	7.14e-06	198	104	6	8d1c74a728040386316fbdcabcdea5fb2b5a76a1
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	KIF18A CHEK1 EZH2 INTS8 PLK1 KIFC1	7.14e-06	198	104	6	880f9817f5145f10f29fc05c5866090433532fe2
ToppCell	distal-mesenchymal-Vascular_Smooth_Muscle-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANGPT1 OLFML2B PPP1R12B ABCC9 PTH1R GFRA1	7.14e-06	198	104	6	5080767ff55326b7d94fca27d398237c4a15c1ed
ToppCell	cellseq-Mesenchymal-Myocytic-Myocytic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANGPT1 OLFML2B SPEG PPP1R12B PTH1R GFRA1	7.14e-06	198	104	6	c7075dce915ab8387309fcb12c5f6a17d4100cda
ToppCell	distal-2-mesenchymal-Vascular_Smooth_Muscle\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANGPT1 EFS OLFML2B PPP1R12B ABCC9 PTH1R	7.14e-06	198	104	6	ce05ede69c167b2294630709bb0c223483a6ef75
ToppCell	severe_influenza-T/NK_proliferative\|severe_influenza / disease group, cell group and cell class (v2)	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.35e-06	199	104	6	638b1491c47f2884daf1c1d38a779ad8e0f59c52
ToppCell	TCGA-Lung-Primary_Tumor\|TCGA-Lung / Sample_Type by Project: Shred V9	CHEK1 EZH2 INTS8 TMEM177 PLK1 KIFC1	7.35e-06	199	104	6	d1d035e987280607266171094db5d6362efe1ad5
ToppCell	COVID-19-Lymphoid-Proliferating_CD4_T_cells\|COVID-19 / Condition, Lineage and Cell class	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.35e-06	199	104	6	e1dfc856a85a91e8f7ab8d600a8a891d16b2aefb
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	CHEK1 EZH2 INTS8 TMEM177 PLK1 KIFC1	7.35e-06	199	104	6	6748d4f76703360071d5f2026d9d06bf30ccfb6d
ToppCell	distal-2-mesenchymal-Airway_Smooth_Muscle\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANGPT1 OLFML2B SPEG PPP1R12B PTH1R GFRA1	7.35e-06	199	104	6	af226a6c50747dad9ca696463e715913b3ac17c0
ToppCell	Control-Control-Lymphocyte-T/NK-T/NK_proliferative\|Control / Disease, condition lineage and cell class	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	6cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	535f6fba8d03873ba35c9949579161dc41cd7a60
ToppCell	Severe_COVID-19-T/NK-proliferating_T/NK\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	52265e761a961f3724b388285e0919bd58847138
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	3c3ac587ad98e3f6be809eac18c7742a23140de1
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	5c84aaedac9f27da0da0493dab7c8f7a4d66888c
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	60d11275f06490f86f400a2802492f9c1b570400
ToppCell	Sepsis-URO-Lymphocyte-T/NK-T/NK_proliferative\|URO / Disease, condition lineage and cell class	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	f277db6cc288a52a5426120c1067608700ee8ccc
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	dd7ad295ab3ba4c19babffb1625900db414bb5a9
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	0e44a55d65b72eb40543d3bde301f8598ac251c3
ToppCell	COVID-19-Lymphoid-Proliferating_CD8_T_cells\|COVID-19 / Condition, Lineage and Cell class	KIF18A CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.56e-06	200	104	6	b239c711cce967826432fdbd5f88eba98a88bb0c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BCAN CR2 CNTNAP4 SLC27A2 MYBPC1	1.64e-05	135	104	5	54b2aaf8d322e01a3ff6099c2422d68ecccf96b4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ELF5 SLC27A2 MYBPC1 EPHA7	2.99e-05	153	104	5	d6526d17826470534b766df144c74e73eb83fdad
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CR2 MYO3B EHMT1 CNTNAP4 TMEM131L	3.28e-05	156	104	5	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRUNE2 SRD5A2 KLHL11 SAA4 SLC27A2	3.59e-05	159	104	5	5543f5aec6352a7c5923e55daf3ed40ff5cc0f0c
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IPP ARHGAP9 CHEK1 GFRA1 ZBTB39	4.28e-05	165	104	5	66f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOX2 ABCB4 ACSL1 REEP6 SLC27A2	4.67e-05	168	104	5	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOX2 ABCB4 ACSL1 REEP6 SLC27A2	4.67e-05	168	104	5	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOX2 ABCB4 ACSL1 REEP6 SLC27A2	4.80e-05	169	104	5	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOX2 ABCB4 ACSL1 REEP6 SLC27A2	4.80e-05	169	104	5	7785cab967a33560830c394c918d6ce625103858
ToppCell	facs-Heart-RV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP9 MYO3B WSCD2 PLK1 KIFC1	5.08e-05	171	104	5	dbffd55db0b3fc6eeb38d05189d84653f0111b31
ToppCell	facs-Heart-RV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP9 MYO3B WSCD2 PLK1 KIFC1	5.08e-05	171	104	5	eee1199332c09aaae021134ee7c91661b11df50a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2B ARHGAP9 ABCB4 ACSL1 NLRP5	5.22e-05	172	104	5	72fbfa890995e47048b47199c170cc7dcd7661f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2B ARHGAP9 ABCB4 ACSL1 NLRP5	5.22e-05	172	104	5	2ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CHEK1 EZH2 ANO6 PLK1	5.22e-05	172	104	5	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANGPT1 ABCC9 TMEM255B ANO6 MYBPC1	5.51e-05	174	104	5	43c0e758fa8683708475aec846929ac70d41d7f5
ToppCell	(03)_Secretory-(0)_uninjured\|(03)_Secretory / shred by cell type and Timepoint	ANGPT1 ACOX2 ELF5 CAPN5 SLC27A2	5.51e-05	174	104	5	ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NPR2 BCAN TMEM255B NCAN	5.66e-05	175	104	5	d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHEK1 EZH2 PTH1R WSCD2 KIFC1	5.66e-05	175	104	5	a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NPR2 BCAN TMEM255B NCAN	5.66e-05	175	104	5	1d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CLGN CHEK1 DCLRE1A PLK1 KIFC1	5.82e-05	176	104	5	941e8724b6f680719ef2a4f190f943b205bb9e78
ToppCell	facs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOX2 TCHH REEP6 ASCC2 ELF5	5.98e-05	177	104	5	e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCell	facs-Lung-nan-3m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOX2 TCHH REEP6 ASCC2 ELF5	5.98e-05	177	104	5	b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN9 ANGPT1 PTH1R KL ATP6V0A4	5.98e-05	177	104	5	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IDUA EZH2 EIF6 PLK1 MFSD5	6.30e-05	179	104	5	327cc39161741ddbc4e8d45b9b3d30b3ce508929
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CHEK1 EZH2 PLK1 KIFC1	6.47e-05	180	104	5	5e1680088065be14447d5d5465f91f7edd071a1e
ToppCell	droplet-Kidney-nan-18m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INS PTH1R ACSL1 KL SLC27A2	6.47e-05	180	104	5	cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF18A TOMM20L REEP6 PLK1 PLP2	6.64e-05	181	104	5	d74ee84146a72fd7cddf287f2e66d47d2c683bc4
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 BCAN TMEM255B NCAN PTPN20	6.64e-05	181	104	5	1037051eb82313c13346617b33f3c4c648181c4d
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CHEK1 ABLIM2 PLK1 KIFC1	6.82e-05	182	104	5	3948422707d6d5e021bcd7158e2eb69143613f62
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CHEK1 ABLIM2 PLK1 KIFC1	6.82e-05	182	104	5	fe46819c153a81911864473badc794f243705f98
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	CAPN9 TTYH3 SIM2 CAPN5 MYBPC1	7.00e-05	183	104	5	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	IIF-Lymphocyte-T_NK-T_NK_proliferative\|IIF / Disease, Lineage and Cell Type	KIF18A CLGN CHEK1 EZH2 PLK1	7.18e-05	184	104	5	ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHEK1 PLK1 PLP2 KIFC1 MYBPC1	7.18e-05	184	104	5	4b864c74e2cf7e58d6bd151f955c43d72f035d52
ToppCell	URO-Lymphocyte-T_NK-T_NK_proliferative\|URO / Disease, Lineage and Cell Type	KIF18A CHEK1 EZH2 KIFC1 SLC27A2	7.37e-05	185	104	5	0ae9c646679c69a553eda670aef0e0495feb0286
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.37e-05	185	104	5	9d424a8608b339dd6129c58d87626678d4ec4af7
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A EZH2 INTS8 GFRA1 EPHA2	7.56e-05	186	104	5	3993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A EZH2 INTS8 GFRA1 EPHA2	7.56e-05	186	104	5	ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PRUNE2 KIF18A PPP1R12B ANO6 SLC27A2	7.56e-05	186	104	5	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SLC66A2 TTYH3 PTH1R KL	7.56e-05	186	104	5	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTH1R XXYLT1 ABLIM2 RECK EPHA7	7.75e-05	187	104	5	b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTH1R XXYLT1 ABLIM2 RECK EPHA7	7.75e-05	187	104	5	9fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CHEK1 EZH2 PLK1 KIFC1	7.75e-05	187	104	5	4d12c70c8ed922fbc8f7b139145611203735cab4
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CHEK1 EZH2 PLK1 KIFC1	7.75e-05	187	104	5	e46b49b4053d2d0f3e1d2bcdc380f7f8733cbe07
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTH1R XXYLT1 ABLIM2 RECK EPHA7	7.75e-05	187	104	5	e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTH1R ACSL1 KL ATP6V0A4 SLC27A2	7.75e-05	187	104	5	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A EFS ODC1 EZH2 PLK1	7.75e-05	187	104	5	38ee33295a21db4aae5ba085df033db9693e41c6
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CHEK1 EZH2 PLK1 KIFC1	7.75e-05	187	104	5	e851ee46a6b4068a7bd7602ee183c0ace50ee4dd
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A EFS ODC1 EZH2 PLK1	7.75e-05	187	104	5	dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 TTYH3 PTH1R SLC27A2 EPHA7	7.95e-05	188	104	5	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	CHEK1 EZH2 PLK1 KIFC1 SLC27A2	7.95e-05	188	104	5	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	droplet-Marrow-nan-18m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INS OLFML2B DBNL ARHGAP9 PLP2	7.95e-05	188	104	5	fa7a612b0a2b35de5f76a0408168dabe5db00773
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 BCAN TMEM255B NCAN PTPN20	7.95e-05	188	104	5	006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 BCAN TMEM255B NCAN PTPN20	7.95e-05	188	104	5	d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 TTYH3 PTH1R SLC27A2 EPHA7	7.95e-05	188	104	5	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	normal-na-Lymphocytic\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CHEK1 EZH2 PLK1 KIFC1 SLC27A2	8.15e-05	189	104	5	1d382f8eb998c6a30e09fddc9a427afc8f5f7323
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 TTYH3 PTH1R SLC27A2 EPHA7	8.15e-05	189	104	5	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 TTYH3 PTH1R SLC27A2 EPHA7	8.15e-05	189	104	5	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	normal-na-Lymphocytic-lymphocyte\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CHEK1 EZH2 PLK1 KIFC1 SLC27A2	8.15e-05	189	104	5	b83fd81ecc5ef363be7435ee12cb7079e2434af7
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SPEG ABCC9 WSCD2 EPHA7	8.15e-05	189	104	5	4dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SPEG ABCC9 WSCD2 EPHA7	8.15e-05	189	104	5	0d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCell	normal-na-Lymphocytic-lymphocyte-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CHEK1 EZH2 PLK1 KIFC1 SLC27A2	8.15e-05	189	104	5	3db4177d68cab4cd16842d2ebcaca28f69300e44
ToppCell	Int-URO-Lymphocyte-T_NK-T_NK_proliferative\|Int-URO / Disease, Lineage and Cell Type	KIF18A CHEK1 EZH2 PLK1 KIFC1	8.35e-05	190	104	5	005967c540418b85311308072a07c684f4296aef
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANGPT1 PPP1R12B KL ATP6V0A4 SDHD	8.35e-05	190	104	5	223587b5df037794a2cee234babf87d12bf48ac8
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFS BCAN TMEM255B ABCB4 NCAN	8.35e-05	190	104	5	9b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFS BCAN TMEM255B ABCB4 NCAN	8.35e-05	190	104	5	d146af1926474328a7c822bc140c4dda66e1bbfb
Disease	nervous system disease (implicated_via_orthology)	KIF1A KIF1B KIF1C	8.88e-06	12	103	3	DOID:863 (implicated_via_orthology)
Disease	Liver carcinoma	KIF18A STAB2 OLFML2B EZH2 PTH1R ABCB4 CNTNAP4 PLK1 INS-IGF2 KIFC1	1.16e-05	507	103	10	C2239176
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A KIF1B	7.21e-05	4	103	2	DOID:0050890 (biomarker_via_orthology)
Disease	aspartate aminotransferase to alanine aminotransferase ratio	PRUNE2 DIP2B ARHGAP9 ACOX2 ABCB4 EPHA2	1.97e-04	239	103	6	EFO_0010934
Disease	latent autoimmune diabetes in adults, type 2 diabetes mellitus	INS INS-IGF2	4.28e-04	9	103	2	EFO_0009706, MONDO_0005148
Disease	N-acetylglycine measurement	MYO3B MGME1	1.07e-03	14	103	2	EFO_0021002
Disease	familial atrial fibrillation (is_implicated_in)	ABCC9 NUP155	1.07e-03	14	103	2	DOID:0050650 (is_implicated_in)
Disease	Endometrial Neoplasms	SRD5A2 ABCC9 EZH2	1.11e-03	58	103	3	C0014170
Disease	reticulocyte measurement	ANGPT1 ARHGAP9 SKI EIF6 ABCB4 KLHL11 WIZ PRKAA1 ASCC2 TMEM131L MYBPC1	1.13e-03	1053	103	11	EFO_0010700
Disease	anthranilic acid measurement	KIF1B MYO3B	1.40e-03	16	103	2	EFO_0010460
Disease	Pheochromocytoma, Extra-Adrenal	KIF1B SDHD	1.40e-03	16	103	2	C1257877
Disease	Liver Cirrhosis, Experimental	PRUNE2 INS OLFML2B ARHGAP9 GFRA1 ACOX2 ACSL1 ANO6 RECK	1.57e-03	774	103	9	C0023893
Disease	Charcot-Marie-Tooth disease type 2	KIF1B DYNC1H1	1.59e-03	17	103	2	cv:C0270914
Disease	type 1 diabetes mellitus	EFS INS ACSL1 INS-IGF2 RBM17	1.62e-03	242	103	5	MONDO_0005147
Disease	Alopecia	SRD5A2 ODC1	1.99e-03	19	103	2	C0002170
Disease	Pheochromocytoma	KIF1B SDHD	1.99e-03	19	103	2	C0031511
Disease	Endometrial Carcinoma	SRD5A2 ABCC9 EZH2	2.07e-03	72	103	3	C0476089
Disease	serum IgG glycosylation measurement	STAB2 ANGPT1 SKI TMEM255B GFRA1 EYS RECK	2.42e-03	523	103	7	EFO_0005193
Disease	gastric ulcer (biomarker_via_orthology)	ANGPT1 IDUA	2.43e-03	21	103	2	DOID:10808 (biomarker_via_orthology)
Disease	HbA1c measurement	DIP2B INS CR2 KL ASCC2 TMEM131L INS-IGF2 KIF1C	2.55e-03	675	103	8	EFO_0004541
Disease	ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)	ABCC9 NUP155	2.66e-03	22	103	2	C1843687
Disease	prostate carcinoma (is_marker_for)	ANGPT1 PLK1	2.91e-03	23	103	2	DOID:10286 (is_marker_for)
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	KIF1B SDHD	2.91e-03	23	103	2	C1708353
Disease	sphingomyelin measurement	DIP2B PPP1R12B NCAN DYNC1H1 KPNB1	2.96e-03	278	103	5	EFO_0010118
Disease	Colorectal Carcinoma	SLC66A2 EFS IPP ODC1 ABCB4 KL MS4A5 EPHA7	3.23e-03	702	103	8	C0009402
Disease	Impaired glucose tolerance	INS PRKAA1	3.44e-03	25	103	2	C0271650

Protein segments in the cluster

Peptide	Gene	Start	Entry
SALGCYDGNVYERLF	ACOX2	636	Q99424
EGNIQYLFLEYCSGG	CHEK1	76	O14757
LRAALGCQFYEGYGQ	ACSL1	446	P33121
FVVVCGDGEYIIYTA	COPB2	366	P35606
GGFLETYEALCDYNG	CARMIL2	156	Q6F5E8
DLGEGFILACLEYYH	ASCC2	481	Q9H1I8
GCLENLYYNGVDIID	CNTNAP4	331	Q9C0A0
GFFVRQGEYICTLDY	ABLIM2	61	Q6H8Q1
DQTYYVAGFSILCGA	ABCC9	1031	O60706
CADVYQAGFNKSGIY	ANGPT1	286	Q15389
NLIAGCFYDGILLYA	NPR2	331	P20594
AYAKLAGCYQALDGG	CAPN5	166	O15484
FAGLCYFNYHDVGIC	SDHD	136	O14521
RCFGVYAGTAILVNY	DISP1	631	Q96F81
EFVEAAGLCGEYLYF	ELF5	106	Q9UKW6
AGLCGEYLYFILQNI	ELF5	111	Q9UKW6
YYLDAVVSFIECGNA	AFF4	941	Q9UHB7
VDYYGDCQAVGVLSE	RECK	781	O95980
QVCYDLGAAYFQQGS	INTS8	251	Q75QN2
AYLGVAALNDCIYSV	IPP	476	Q9Y573
VEALYLVCGERGFFY	INS	36	P01308
LHEAGYDAYITGLCF	PARN	376	O95453
LAAVVGVACFLYGYL	ANO6	311	Q4KMQ2
QLYAAYLGGYEQCDA	BCAN	191	Q96GW7
NFVALNYDGICYLGG	EYS	3096	Q5T1H1
AGANCVLDPLVYYFS	LPAR5	286	Q9H1C0
LNYIGLLDCVAEYQG	MGME1	231	Q9BQP7
GIICNYTIFYQAEGG	IL31RA	451	Q8NI17
FLNGYNCTVLAYGAT	KIF18A	101	Q8NI77
FEGYNVCIFAYGQTG	KIF1B	86	O60333
QSALDGYPVCIFAYG	KIFC1	396	Q9BW19
RVLIGTYYDNFCAIA	EZH2	441	Q15910
RCVADNTNLYVFGGY	KLHDC10	96	Q6PID8
IGISCSYGQVLFAVY	OR2L8	211	Q8NGY9
GIELIAAFYGCLYAG	DIP2B	1056	Q9P265
FEGYNVCIFAYGQTG	KIF1C	86	O43896
SLQDFCAALYYVLEG	NLRP5	586	P59047
TFGFILDQNYICGYS	MS4A5	136	Q9H3V2
GFYLAFQDVGACIAL	EPHA7	181	Q15375
IFLAGKDGCLYEVAY	NUP155	226	O75694
VLGLIATCLFGYDAY	PLP2	116	Q04941
SYAGCFRFGAYLIVN	ABCB4	951	P21439
NTYCLVAIGGSENFY	EIF6	21	P56537
IVNCGEEYFYIATQG	PTPN20	216	Q4JDL3
GYGASLLCNLIGFVY	REEP6	51	Q96HR9
KAGYNLTICYFAIGD	IFT88	306	Q13099
GAAICYYKDDVFIIG	KLHL11	601	Q9NVR0
GNEVSYECDQGFYLL	CR2	741	P20023
NYADCLLAYSGLIGT	GFRA1	281	P56159
KGFYLAFQDIGACVA	EPHA2	176	P29317
LRDDGCQAYYLQGGF	DUSP7	161	Q16829
GDLQLLYFYAGQCQS	EFS	431	O43281
QGFLNYYDACSEGLR	IDUA	196	P35475
AKVGSQEAFYLYACG	LYST	1676	Q99698
YAEYQVCLAAVGLVG	KPNB1	661	Q14974
DCLLSAAFIAYAGYF	DYNC1H1	3506	Q14204
AHILDGINLCGYFAY	KL	901	Q9UEF7
GINLCGYFAYSFNDR	KL	906	Q9UEF7
AFQYGVVEGCTAYFL	DCLRE1A	716	Q6PJP8
FGANVLTIGYAIYEC	CAPN9	411	O14815
YNGYLCIAVAAGAGT	SLC31A1	156	O15431
VYLQGLIDCYLFGNS	SAA4	81	P35542
DGEVYCIDARFYGNV	EHMT1	1181	Q9H9B1
YYVNDGVYGSFNCIL	ODC1	316	P11926
GQGLCARALYDYQAA	DBNL	371	Q9UJU6
YFLEGQIAILYVCGL	MFSD5	71	Q6N075
VEALYLVCGERGFFY	INS-IGF2	36	F8WCM5
FEGYNVCIFAYGQTG	KIF1A	86	Q12756
EFLYGVQGSCAADLY	PARP6	21	Q2NL67
AFDGYNACIFAYGQT	KIF13B	91	Q9NQT8
YYGDGLNAIIVFAAC	PRUNE2	2911	Q8WUY3
INAYACLVCGKYFQG	USP39	131	Q53GS9
INGYNCQGYGFEVLD	TMEM131L	786	A2VDJ0
AYYEFIGVSGCQDVL	TMEM255B	176	Q8WV15
ICIYEFYAATEGNIG	SLC27A2	356	O14975
VYCFARELGGEVFYV	NCAN	251	O14594
YDSCYQIVGLVAVGQ	SIM2	201	Q14190
FLLLGCNNGSIYYVD	SHKBP1	336	Q8TBC3
YQPYGAAVGLSACVF	WIZ	406	O95785
NFYGNCFVICGVLYA	OLFML2B	671	Q68BL8
DAERLCNALLYGGAY	SKI	181	P12755
VSGVLYYKCGAQFAL	ABCB7	281	O75027
YVSGGELFDYICKNG	PRKAA1	106	Q13131
YEVNFQDGIDCGGAY	CLGN	141	O14967
YGCLKFGGQAYSDVE	TM2D2	101	Q9BX73
DAGFYTCKAVNEYGA	SPEG	936	Q15772
AGYAGCRVAVTFFLY	PTH1R	276	Q03431
YFGGRVVKACFYNLD	RBM17	376	Q96I25
GNGVLQGYYLIYCAE	SRD5A2	121	P31213
YEGDGFLCYGNAAVE	STAB2	986	Q8WWQ8
QLCALYAFTYTGADG	ARHGAP9	26	Q9BRR9
ALIVFSCIYGEGYSN	nan	36	A8MWL6
ALIVFSCIYGEGYSN	SYNGR2	36	O43760
AVLACAAGYFQNLFL	ZBTB39	46	O15060
GIFSIYTGLIYNDCF	ATP6V0A4	456	Q9HBG4
ACGAFAFLGYCIYLN	TOMM20L	16	Q6UXN7
LSSAFLGYVLYGECQ	TMEM42	111	Q69YG0
DNCAERGYLYGGLEF	WSCD2	161	Q2TBF2
AYACGGVEFYEKLLS	TMEM177	241	Q53S58
LDYVQALTGFCYDGV	TTYH3	371	Q9C0H2
ALTGFCYDGVEGLIY	TTYH3	376	Q9C0H2
CYDGVEGLIYLALFS	TTYH3	381	Q9C0H2
LFIFKVAQACYYALG	TCHH	76	Q07283
VAQACYYALGQATGL	TCHH	81	Q07283
YVQCVLAFTGVAGYI	SLC66A2	146	Q8N2U9
AALAVCAFYYLGSGR	XXYLT1	31	Q8NBI6
YGLGYQLCDNSVGVL	PLK1	421	P53350
CFGIQHYAGKVLYDA	MYO3B	831	Q8WXR4
AAGLDGYVLEYCFEG	MYBPC1	746	Q00872
AASCGYLNIAEYFIN	PPP1R12B	131	O60237