Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

TRMT10A ASH1L

3.17e-03172102GO:0008757
GeneOntologyMolecularFunctionmethyltransferase activity

TRMT10A ASH1L

4.82e-03213102GO:0008168
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

TRMT10A ASH1L

5.31e-03224102GO:0016741
DomainTPR

CFAP46 TTC31

4.05e-03165112PS50005
DomainTPR_REGION

CFAP46 TTC31

4.05e-03165112PS50293
Domain-

CFAP46 TTC31

6.30e-032071121.25.40.10
DomainTPR-like_helical_dom

CFAP46 TTC31

7.91e-03233112IPR011990
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

SF3B2 ASH1L

3.94e-053011217403666
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

SF3B2 NKTR AP3D1

1.17e-0431711317620599
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

CFAP46 TTC31

1.10e-0311582769
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

NKTR ZBED6 ASH1L

1.16e-05188113ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

NKTR ZBED6 ASH1L

1.29e-05195113d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKTR ZBED6 ASH1L

1.29e-051951135c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

NKTR RPL41

1.12e-04651126e074496433d86c2818e72f18cdbe00eb33333b7
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

NKTR ASH1L

3.88e-0412111219333a660800b583fa27b495c1f7828e6636a257
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NKTR ASH1L

4.83e-04135112b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SMO CFAP46

4.97e-04137112761cc0e2b4971e98f6d0691d4575b5cd208b602d
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 TRMT10A

5.64e-0414611226493014daa432db721613ef480d133f3da9eb58
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

NKTR ASH1L

5.72e-0414711294998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

NKTR ASH1L

6.44e-04156112afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

NKTR ASH1L

6.94e-04162112b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SMO TRMT10A

6.94e-04162112a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SMO TRMT10A

7.19e-04165112a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCellLAM-Myeloid-Mast|LAM / Condition, Lineage and Cell class

SRPK3 RPL41

7.28e-04166112e0ce973cc2a091b832c67b3b32dc153379daa2ef
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMO RPL41

7.81e-04172112bd01b39a5699824ab14827cc9dc98e547d65b160
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMO RPL41

7.99e-04174112911eac6f6ec1e5e85348a7fe774243498388a810
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SRPK3 RPL41

7.99e-041741127c8704766dd4c80250754b5ee9907b342b9c2623
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SRPK3 RPL41

7.99e-0417411226ca6ebaa0081108d44c01f8ca56a63724f1c99d
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SRPK3 RPL41

7.99e-041741129aa2168d3bcef7cdc5a47442618cb8e9eb24c95b
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

8.18e-041761129b58734017ceabe81f490dd0b9f3192bc903d455
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBED6 ASH1L

8.36e-0417811201dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SRPK3 RPL41

8.36e-04178112525c4b3f9736ff206e2f1378c2a29ba4f13ba22f
ToppCellLAM-Myeloid-Mast|Myeloid / Condition, Lineage and Cell class

SRPK3 RPL41

8.36e-0417811219cb1a46ba2f5c19180b6b0586acfaf075afff1c
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SRPK3 RPL41

8.36e-041781128ef229f38aa8a2ae8b366c3ce26d4cb1302d674a
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SRPK3 RPL41

8.36e-041781128d74c12c4b0ce8bcb0f59151bdc67036997095ef
ToppCelldroplet-Thymus-nan-24m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

8.36e-041781129c6cb39647d5a040ae325bc75148dfddbff7621e
ToppCellfacs-Kidney-nan-18m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 TRMT10A

8.46e-04179112f4fd214a9865c635d8a744ce5e0eff45174d3de4
ToppCellfacs-Kidney-nan-18m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 TRMT10A

8.46e-0417911257d8d44a793314eec8f77030f4177bfe21d41652
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

NKTR ASH1L

8.64e-04181112f2315414e714ac86211546a935660c4be6e85f1b
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL41 ASH1L

8.74e-04182112eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

8.74e-041821126946ab8d91fb8dce5af065f57a13659b8d97ed5c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL41 ASH1L

8.83e-041831123fa608aa6b119869ec3280dc388dfee57160e63a
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL41 ASH1L

8.83e-0418311228cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Limb_Muscle-nan-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

9.03e-04185112a01d25a5642337cfcdef5fcd189b3150a5fad911
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBED6 ASH1L

9.03e-04185112eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

9.03e-0418511298bb853c495eb16c3663685a8e20755bd309b520
ToppCellfacs-Kidney-nan-18m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 TRMT10A

9.03e-04185112a3b937163346d729115e6335336e33d3e71fccb0
ToppCelldroplet-Marrow-nan-18m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMO RPL41

9.03e-04185112de353368f4f6a7a0a66e391d586879876fbe2734
ToppCelldroplet-Mammary_Gland-nan-18m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

9.12e-04186112124a618a0911aba9fc2a071dc3ca40fc003bb1ed
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL41 ASH1L

9.32e-04188112d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

NKTR ASH1L

9.32e-04188112b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 RPL41

9.32e-041881127c542b226240adcb7797be0ded6523e5732f0078
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-B_cell-B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 RPL41

9.32e-041881129526d9e035eadbb0dcd4ad6e79a3a2b7f7845d74
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

9.62e-041911129502533a7946626e1714a22a0f16c70d296edf16
ToppCellfacs-Marrow-B-cells|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RPL41

9.62e-04191112f84cd55e6fb112d271d35db11ad7648e03186e46
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKTR ZBED6

9.62e-041911127d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

NKTR RPL41

9.62e-041911121ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

NKTR ASH1L

9.72e-041921129cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 RPL41

9.72e-04192112b0686c0676f7658b560967840adb6c182792b075
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

NKTR ASH1L

9.72e-0419211247646d7e4990be85072987f92bf18d52f8da752e
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-B_cell-B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 RPL41

9.72e-041921127e626ec5a4615e7e04a324937d5f0147dd17ca8e
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKTR AP3D1

9.82e-04193112471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKTR AP3D1

9.82e-04193112fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellASK428-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

NKTR RPL41

9.82e-04193112bca9bf941193feea8ed56735041513185c165135
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 RPL41

9.82e-04193112a808eb426b4ce9ddf7d6556b083abd9232a218b1
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-B_cell-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 RPL41

9.82e-04193112e1d0b2d2d6b65d32922e22d092848ac4200669d5
ToppCellTracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RPL41 ZBED6

9.82e-0419311291a1c9b8390cbd881db8c49d8f34feca0d1067d6
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

SF3B2 AP3D1

9.92e-041941124903a0d6e36599bcb83b179462e5b949df9eb685
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBED6 ASH1L

9.92e-04194112e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKTR ASH1L

1.00e-031951127796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKTR ASH1L

1.00e-031951123e519cffa6144a62b06124642a14c9ff39b76554
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SRPK3 CFAP46

1.02e-031971126e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

NKTR RPL41

1.02e-03197112e666f6580e9a20b5e550f02125706db17eec8510
ToppCellHealthy_donor|World / disease group, cell group and cell class (v2)

NKTR RPL41

1.03e-031981121ed0b50c9754727a05c27b21f3546bf2e37eef7f
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NKTR ASH1L

1.03e-031981124c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NKTR ASH1L

1.04e-03199112f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellHealthy/Control|World / Disease group and Cell class

NKTR RPL41

1.04e-031991122623c42b3e79e401a485879b52e8bbcbc581544d
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

NKTR ASH1L

1.04e-03199112952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NKTR ASH1L

1.05e-0320011212f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NKTR ASH1L

1.05e-03200112dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellSigmoid-T_cell-Activated_CD4_T|T_cell / Region, Cell class and subclass

RPL41 ASH1L

1.05e-032001129c21e6b8d4f8e526950adacf9cc45a5e86d81c1f
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

NKTR ASH1L

5.83e-045082GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

NKTR ASH1L

5.83e-045082GAVISH_3CA_METAPROGRAM_B_CELLS_B_CELLS_1
ComputationalNeighborhood of SMO

SMO ASH1L

8.40e-046082GCM_SMO

Protein segments in the cluster

PeptideGeneStartEntry
KRQKRKRKKKYPQLR

ASH1L

1266

Q9NR48
KVKKLRLRRGKKKRG

CFAP46

611

Q8IYW2
KRRKKRKEKEKKGKR

AP3D1

741

O14617
RKKRMRRLKRKRRKM

RPL41

6

P62945
HKRRPKVKRSKKRRK

NKTR

226

P30414
NKRKKMRRKRKQQKR

SRPK3

266

Q9UPE1
KEKNRKRRNRKKKKK

SF3B2

321

Q13435
KRRNRKKKKKPQRVR

SF3B2

326

Q13435
QKRLGRKKKRRKRKK

SMO

666

Q99835
RKKKRRKRKKEVCPL

SMO

671

Q99835
KKKRKKGLRIKGKRR

ZBED6

61

P86452
RKQKRKEKRKRKKLE

TRMT10A

61

Q8TBZ6
KKRLKKKRQKERKRQ

TTC31

176

Q49AM3