Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

THBD TBC1D9B PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 CUBN ADGRL3

1.96e-117495016GO:0005509
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.94e-141875012GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 ADGRL3

3.79e-133135013GO:0098742
GeneOntologyBiologicalProcesscell-cell adhesion

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 CD46 PCDHA1 ITGB6 VSIR ADGRL3

2.51e-0910775016GO:0098609
GeneOntologyBiologicalProcesscardiac left ventricle formation

PCDHA12 PCDHA10

3.44e-054502GO:0003218
MousePhenodecreased lung tissue damping

FNIP1 ITGB6

1.93e-053362MP:0011048
DomainCadherin_tail

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.36e-23374912PF15974
DomainCadherin_CBD

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.36e-23374912IPR031904
DomainCadherin_N

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

9.00e-20654912IPR013164
DomainCadherin_2

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

9.00e-20654912PF08266
DomainCadherin_CS

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

6.46e-171094912IPR020894
DomainCadherin

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.01e-161134912PF00028
DomainCADHERIN_1

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.01e-161134912PS00232
DomainCADHERIN_2

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.13e-161144912PS50268
Domain-

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.13e-1611449122.60.40.60
DomainCA

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.26e-161154912SM00112
DomainCadherin-like

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.40e-161164912IPR015919
DomainCadherin

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.73e-161184912IPR002126
DomainGAIN_dom_N

ADGRB1 ADGRL3

3.65e-0411492IPR032471
DomainGAIN

ADGRB1 ADGRL3

3.65e-0411492PF16489
DomainHormR

ADGRB1 ADGRL3

1.95e-0325492SM00008
DomainHRM

ADGRB1 ADGRL3

2.44e-0328492PF02793
DomainARF

ARF4 ARF5

2.62e-0329492PS51417
DomainSmall_GTPase_ARF

ARF4 ARF5

2.62e-0329492IPR024156
DomainArf

ARF4 ARF5

2.99e-0331492PF00025
DomainSmall_GTPase_ARF/SAR

ARF4 ARF5

3.38e-0333492IPR006689
DomainGPS

ADGRB1 ADGRL3

3.59e-0334492SM00303
DomainGPS

ADGRB1 ADGRL3

3.80e-0335492PF01825
DomainGPS

ADGRB1 ADGRL3

4.01e-0336492PS50221
DomainGPS

ADGRB1 ADGRL3

4.24e-0337492IPR000203
DomainG_PROTEIN_RECEP_F2_1

ADGRB1 ADGRL3

4.94e-0340492PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRB1 ADGRL3

4.94e-0340492PS50227
DomainGPCR_2_extracellular_dom

ADGRB1 ADGRL3

4.94e-0340492IPR001879
DomainCadherin_C_2

PCDHA9 PCDHA7

5.43e-0342492PF16492
DomainCadherin_C

PCDHA9 PCDHA7

5.43e-0342492IPR032455
DomainG_PROTEIN_RECEP_F2_2

ADGRB1 ADGRL3

7.62e-0350492PS00650
Domain7tm_2

ADGRB1 ADGRL3

7.62e-0350492PF00002
DomainGrowth_fac_rcpt_

THBD RSPO2 CUBN

7.95e-03156493IPR009030
DomainSushi

PAPPA2 CD46

8.22e-0352492PF00084
DomainCCP

PAPPA2 CD46

8.85e-0354492SM00032
DomainSUSHI

PAPPA2 CD46

9.49e-0356492PS50923
DomainSushi_SCR_CCP_dom

PAPPA2 CD46

9.82e-0357492IPR000436
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.43e-3215521215640798
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.95e-3117521229911975
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

5.83e-3118521210662547
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

5.83e-3118521215570159
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

8.44e-2924521224698270
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

9.46e-2828521215347688
Pubmed

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4

9.85e-25115299655502
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.13e-2357521232633719
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.69e-2358521230377227
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.17e-2268521211230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.56e-2272521210380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

6.50e-2274521210817752
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

7.73e-2275521215372022
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.08e-2177521210835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.77e-2180521210716726
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.68e-19119521228625976
Pubmed

Proteins of the CNR family are multiple receptors for Reelin.

PCDHA9 PCDHA13 PCDHA11 PCDHA7 PCDHA6 PCDHA5 PCDHA4

8.63e-181252710612399
Pubmed

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.03e-16193521222589738
Pubmed

Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease.

PCDHA9 PCDHA12 PCDHA10 PCDHA7

2.22e-11552434888534
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

PCDHA9 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA3 PCDHA2 PCDHA1

5.57e-11329521017474147
Pubmed

Identification of two novel PCDHA9 mutations associated with Hirschsprung's disease.

PCDHA9 PCDHA12 PCDHA10

3.15e-09352329477871
Pubmed

Molecular mechanisms governing Pcdh-gamma gene expression: evidence for a multiple promoter and cis-alternative splicing model.

PCDHA11 PCDHA5 PCDHA4

2.63e-07952312154121
Pubmed

Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.

PCDHA12 PCDHA10 PCDHA6 PCDHA1

1.90e-065952423754746
Pubmed

PCDHA9 as a candidate gene for amyotrophic lateral sclerosis.

PCDHA12 PCDHA10

2.19e-06252238467605
Pubmed

Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses.

ARF4 ARF5

2.19e-06252222105072
Pubmed

Deletion of Class II ADP-Ribosylation Factors in Mice Causes Tremor by the Nav1.6 Loss in Cerebellar Purkinje Cell Axon Initial Segments.

ARF4 ARF5

6.57e-06352231201232
Pubmed

GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER transport involved in regulation of lipid homeostasis.

ARF4 ARF5

6.57e-06352222185782
Pubmed

The Genetic Landscape of Hypoplastic Left Heart Syndrome.

PCDHA12 PCDHA10

6.57e-06352229569026
Pubmed

Human and Giardia ADP-ribosylation factors (ARFs) complement ARF function in Saccharomyces cerevisiae.

ARF4 ARF5

6.57e-0635221447192
Pubmed

Structural Basis of Diverse Homophilic Recognition by Clustered α- and β-Protocadherins.

PCDHA9 PCDHA7

6.57e-06352227161523
Pubmed

Interaction of calcium-dependent activator protein for secretion 1 (CAPS1) with the class II ADP-ribosylation factor small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network.

ARF4 ARF5

6.57e-06352220921225
Pubmed

Two novel CNRs from the CNR gene cluster have molecular features distinct from those of CNR1 to 8.

PCDHA2 PCDHA1

6.57e-06352211401448
Pubmed

Identification of arfophilin, a target protein for GTP-bound class II ADP-ribosylation factors.

ARF4 ARF5

6.57e-06352210593962
Pubmed

Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing.

THBD LPA

6.57e-06352230341568
Pubmed

Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.

PCDHA13 PCDHA12 PCDHA10

1.01e-052852333523829
Pubmed

Two distinct populations of ARF bound to Golgi membranes.

ARF4 ARF5

1.31e-0545228491770
Pubmed

RNA interference characterization of proteins discovered by proteomic analysis of pancreatic cancer reveals function in cell growth and survival.

CD46 ITGB6

1.31e-05452221934552
Pubmed

ADP-ribosylation factor is functionally and physically associated with the Golgi complex.

ARF4 ARF5

2.19e-0555222105501
Pubmed

Calcium-dependent activator protein for secretion 2 interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.

ARF4 ARF5

2.19e-05552222111578
Pubmed

An Arf/Rab cascade controls the growth and invasiveness of glioblastoma.

ARF4 ARF5

3.28e-05652233443570
Pubmed

WLS retrograde transport to the endoplasmic reticulum during Wnt secretion.

ARF4 ARF5

3.28e-05652224768165
Pubmed

Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome.

THBD CD46

4.58e-05752220513133
Pubmed

Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells.

ARF4 ARF5

6.10e-0585228195219
Pubmed

Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

ARF4 ARF5

6.10e-0585228947846
Pubmed

Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol.

ARF4 ARF5

6.10e-0585228355790
Pubmed

The complex genetics of hypoplastic left heart syndrome.

PCDHA12 PCDHA10

6.10e-05852228530678
Pubmed

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

ATR HUWE1

9.79e-051052217478428
Pubmed

Hemostatic gene polymorphisms in young Sardinian with non-fatal acute myocardial infarction.

THBD LPA

9.79e-051052220036902
Pubmed

Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.

ARF4 ARF5

9.79e-051052210828067
Pubmed

Genetic Atypical Hemolytic-Uremic Syndrome

THBD CD46

1.20e-041152220301541
Pubmed

Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.

A1BG DZANK1

1.20e-041152223333597
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

PCDHA13 PCDHA4

1.97e-041452214672974
Pubmed

Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome.

PCDHA12 PCDHA10

2.60e-041652234890862
Pubmed

ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development.

ARF4 ARF5

5.44e-042352237848288
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRB1 ADGRL3

8.67e-042952215203201
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

A1BG PAPPA2 CYFIP1 SLC5A10 MME CUBN ARF5

1.02e-03107052723533145
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRB1 ADGRL3

1.12e-033352225713288
Pubmed

Early embryonic expression of murine coagulation system components.

THBD LPA

1.19e-033452211154109
Pubmed

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics.

CYFIP1 ATR HUWE1

1.35e-0314552328846114
InteractionPCDHA10 interactions

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2

2.81e-24224811int:PCDHA10
InteractionPCDHA8 interactions

PCDHA13 PCDHA12 PCDHA10 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 PCDHA1

6.52e-1555489int:PCDHA8
InteractionFLT3 interactions

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 HUWE1 ARF4

1.33e-143184814int:FLT3
InteractionPCDHA11 interactions

PCDHA9 PCDHA12 PCDHA11 PCDHA10 PCDHA4 PCDHA3 PCDHA1

1.36e-1419487int:PCDHA11
InteractionPCDHA7 interactions

PCDHA9 PCDHA12 PCDHA10 PCDHA7 PCDHA4 PCDHA2

3.91e-1314486int:PCDHA7
InteractionPCDHA4 interactions

PCDHA9 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA4 PCDHA1

9.67e-1160487int:PCDHA4
InteractionPCDHA9 interactions

PCDHA9 PCDHA11 PCDHA10 PCDHA7 PCDHA4 PCDHA3

1.14e-1032486int:PCDHA9
InteractionPCDHA3 interactions

PCDHA9 PCDHA11 PCDHA10 PCDHA6 PCDHA3 PCDHA1

1.69e-1034486int:PCDHA3
InteractionPCDHA1 interactions

PCDHA11 PCDHA4 PCDHA3 PCDHA1

3.54e-099484int:PCDHA1
InteractionPCDHA12 interactions

PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA4

7.88e-0846485int:PCDHA12
InteractionPCDHGA10 interactions

PCDHA9 PCDHA12 PCDHA11 PCDHA4

1.07e-0719484int:PCDHGA10
InteractionLONP2 interactions

PCDHA9 PCDHA12 PCDHA11 PCDHA4 PCDHA3

3.62e-0762485int:LONP2
InteractionMLYCD interactions

PCDHA9 PCDHA12 PCDHA10 PCDHA3

7.42e-0730484int:MLYCD
InteractionPCDHA6 interactions

PCDHA10 PCDHA6 PCDHA3

1.05e-069483int:PCDHA6
InteractionPCDHA2 interactions

PCDHA10 PCDHA7 PCDHA2

4.53e-0614483int:PCDHA2
InteractionPCDHA5 interactions

PCDHA10 PCDHA5

3.32e-054482int:PCDHA5
InteractionRELN interactions

PCDHA10 PCDHA6 PCDHA4

3.56e-0527483int:RELN
InteractionPCDHA13 interactions

PCDHA13 PCDHA10

1.16e-047482int:PCDHA13
InteractionMAP3K6 interactions

PCDHA12 PCDHA4 MAPK4

2.44e-0451483int:MAP3K6
Cytoband5q31

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

6.41e-2111552125q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA9 PCDHA13 PCDHA12 PCDHA11 FNIP1 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.41e-172985213chr5q31
GeneFamilyClustered protocadherins

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.71e-2164391220
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

ARF4 ARF5

2.03e-0331392357
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA2 CD46

6.71e-03573921179
GeneFamilyADAM metallopeptidase domain containing|CD molecules

THBD TSPAN7 CD46 MME

1.00e-02394394471
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 VSIR

7.20e-162385113M2020
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 VSIR

2.39e-152615113MM1277
CoexpressionMIKKELSEN_IPS_WITH_HCP_H3K27ME3

PCDHA13 PCDHA11 PCDHA10 PCDHA4 PCDHA2 ADGRL3

4.96e-08103516M1967
CoexpressionMIKKELSEN_IPS_WITH_HCP_H3K27ME3

PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA2 ADGRL3

5.89e-08106516MM1265
CoexpressionMIKKELSEN_ES_HCP_WITH_H3K27ME3

PCDHA12 PCDHA3 PCDHA2

7.02e-0541513M2000
CoexpressionDESCARTES_FETAL_ADRENAL_CSH1_CSH2_POSITIVE_CELLS

PAPPA2 FAM83G ERVW-1 NLRP2 ITGB6

7.44e-05224515M40145
CoexpressionMIKKELSEN_ES_HCP_WITH_H3K27ME3

PCDHA4 PCDHA3 PCDHA2

7.55e-0542513MM1275
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

PCDHA13 PCDHA12 PCDHA10 PCDHA6 PCDHA5 PCDHA4 PCDHA1

3.52e-06281497PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

PCDHA13 PCDHA12 PCDHA10 PCDHA6 PCDHA5 PCDHA4 PCDHA1

3.52e-06281497PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasDE blastocyst_vs_DE cord blood-Confounder_removed-fold2.0_adjp0.05

PCDHA10 PCDHA6 PCDHA4 PCDHA1

6.83e-0595494PCBC_ratio_DE blastocyst_vs_DE cord blood_cfr-2X-p05
CoexpressionAtlascerebral cortex

TSPAN7 ADGRB1 RSPO2 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA1 MAPK4 ADGRL3

7.32e-0514284912cerebral cortex
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#2

PAPPA2 PCDHA11 PCDHA10 MME NLRP2

9.83e-05201495Arv_EB-LF_1000_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_500

RSPO2 PCDHA11 HUWE1 ADGRL3

2.43e-04132494DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500

RSPO2 PCDHA11 HUWE1 ADGRL3

2.81e-04137494gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#2_top-relative-expression-ranked_500

NAB1 MME HUWE1

2.94e-0456493gudmap_developingKidney_e15.5_Proximal Tubules_500_k2
CoexpressionAtlasPP_RBC_top-relative-expression-ranked_2500_k-means-cluster#2

FBXO7 PCDHA12 PCDHA11 PCDHA10 PCDHA6 PCDHA4 PCDHA3 PCDHA2 NLRP2

2.99e-04957499PP_RBC_2500_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500

THBD RSPO2 PCDHA11 MME HUWE1 ADGRL3

3.33e-04407496gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

RSPO2 PCDHA11 HUWE1 ADGRL3

4.06e-04151494gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_500

RSPO2 PCDHA11 HUWE1

4.36e-0464493gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k1
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

PCDHA11 PCDHA10 PCDHA7 PCDHA3 PCDHA1

1.18e-06159525b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRB1 FBXO7 PCDHA13 PCDHA12 PCDHA7

1.37e-0616452557301178e420983c0cb72178e288a3a0449fdda3
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Nnat_(Neuron.Gad1Gad2.Synpr-Nnat)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCDHA11 PCDHA7 PCDHA2 PCDHA1

3.00e-0685524642755ed2b562dd5e599a04a2b9730e8d29aefe8
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Nnat_(Neuron.Gad1Gad2.Synpr-Nnat)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCDHA11 PCDHA7 PCDHA2 PCDHA1

3.00e-06855242429bacccd103e5b2414264b4aff3103ed9d7cec
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Adenocarcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

PCDHA11 PCDHA3 PCDHA2 PCDHA1

1.72e-051325246480feb3e4e898d610615ce14f598f419c623e07
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(red_nucleus,_magnocellular/parvicellular_(RMC/RPC))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC5A10 PCDHA6 ITGB6

2.00e-0545523a5d7f4dacfdbecf7d82b2bc75fc3668b9a208abb
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(red_nucleus,_magnocellular/parvicellular_(RMC/RPC))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC5A10 PCDHA6 ITGB6

2.00e-05455234e9fd1e4fecb51298f66ca5e1ec87a2a7d314724
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(red_nucleus,_magnocellular/parvicellular_(RMC/RPC))--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC5A10 PCDHA6 ITGB6

2.00e-054552334020aa7499e57d7560d7f5cf91c3bd1e69ce481
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2|E16.5-samps / Age Group, Lineage, Cell class and subclass

RSPO2 PCDHA11 MME SLC4A11

2.05e-0513852405de2cef97c0912fb23f138dd45348f565a14d74
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Atp2b4-Inhibitory_Neuron.Gad1Gad2_Sst.Atp2b4_(Interneuron,_Olm)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

PCDHA11 PCDHA3 SLC4A11

2.13e-05465231259dca3ada3ba697ce50268163bd3b63e3c77bc
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Atp2b4|Hippocampus / BrainAtlas - Mouse McCarroll V32

PCDHA11 PCDHA3 SLC4A11

2.13e-0546523457e258b9b38e581b69ff92fc02d552c24d841cf
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Atp2b4-Inhibitory_Neuron.Gad1Gad2_Sst.Atp2b4_(Interneuron,_Olm)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PCDHA11 PCDHA3 SLC4A11

2.13e-05465235c1cd6647dd412162273fa01a73f65d62d422038
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TSPAN7 PCDHA10 PCDHA7 PCDHA5

2.16e-05140524b9aeb7dda7f377b580dd8a44912f300721437387
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 TSPAN7 MAPK4 ARF4

6.03e-051825245b2bad38c723cd64a7fe7f2dcd361708014c8cfe
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.C1ql3_(VTA_(dorsal_VTA))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PCDHA9 CUBN SLC4A11

6.05e-05655234382d56d5f71c7acfe35f84db7257aba2a7dd36a
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.C1ql3_(VTA_(dorsal_VTA))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PCDHA9 CUBN SLC4A11

6.05e-056552305b712f83d88e864747cd0229a39aca17321e0f8
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCDHA9 PCDHA10 PCDHA5 PCDHA3

6.56e-05186524888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCDHA9 PCDHA12 PCDHA4 PCDHA2

6.69e-051875246c43669e19b5b54d72d1f5d876184fee53c05f0b
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCDHA13 PCDHA5 PCDHA4 PCDHA3

6.83e-05188524e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCellBronchus_Control_(B.)-Endothelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FAM83G PCDHA13 MAPK4 ADGRL3

8.35e-05198524feac39036b5c0ab97b524cc366286942d136d42f
ToppCellBronchus_Control_(B.)-Endothelial-TX-Bronchial_vessel|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FAM83G PCDHA13 MAPK4 ADGRL3

8.35e-05198524dcf334d13e5b0018fee24febccfef91c9e17843b
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TSPAN7 RSPO2 MAPK4 ARF5

8.51e-05199524a900ef002e1ae583b70be0253d8c44dae6754916
DrugAzacitidine

PCDHA9 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

7.97e-104154811ctd:D001374
Drugdimethyl sulfide

PCDHA13 PCDHA12 PCDHA11 PCDHA6

5.48e-0655484CID000001068
Disease1,5 anhydroglucitol measurement

SLC5A10 PCDHA9 FAM83G PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.19e-32294914EFO_0008009
Diseasevisceral adipose tissue measurement, body mass index

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.65e-20874912EFO_0004340, EFO_0004765
Diseaseneutrophil count, basophil count

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 MAPK4

4.04e-172244913EFO_0004833, EFO_0005090
DiseaseAbnormality of refraction

PCDHA9 FBXO7 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 ADGRL3 SLC4A11

1.55e-136734915HP_0000539
Diseasepulse pressure measurement

PAPPA2 CYFIP1 PCDHA9 NAB1 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 CD46 PCDHA1 MAPK4

3.99e-1113924917EFO_0005763
Diseasepost-traumatic stress disorder symptom measurement

PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

7.70e-1182497EFO_0008535
Diseaseneuroticism measurement, cognitive function measurement

PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.07e-105664912EFO_0007660, EFO_0008354
Diseaseneutrophil count

PAPPA2 PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 CD46 PCDHA1 MAPK4 VSIR

3.81e-1013824916EFO_0004833
Diseasepost-traumatic stress disorder

CYFIP1 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.49e-09202498EFO_0001358
Diseasevital capacity

PAPPA2 PCDHA9 PCDHA13 PCDHA12 PCDHA11 PCDHA10 PCDHA7 PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

7.38e-0812364913EFO_0004312
DiseaseHypoplastic Left Heart Syndrome

PCDHA9 PCDHA13

2.69e-055492C0152101
Diseasesystemic lupus erythematosus (is_marker_for)

THBD LPA CD46

6.63e-0547493DOID:9074 (is_marker_for)
Diseasedepressive symptom measurement

PCDHA6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

7.23e-05426496EFO_0007006
Diseaseatypical hemolytic-uremic syndrome (is_implicated_in)

THBD CD46

7.52e-058492DOID:0080301 (is_implicated_in)
DiseaseHemolytic-uremic syndrome

THBD CD46

9.65e-059492cv:C0019061
Diseasefamilial Mediterranean fever (is_marker_for)

THBD LPA

9.65e-059492DOID:2987 (is_marker_for)
DiseaseAtypical hemolytic-uremic syndrome

THBD CD46

9.65e-059492cv:C2931788
DiseaseAtypical Hemolytic Uremic Syndrome

THBD CD46

1.21e-0410492C2931788
Diseasecoronary artery disease (is_marker_for)

THBD LPA CCL26

1.91e-0467493DOID:3393 (is_marker_for)
DiseaseAlzheimer disease, gastroesophageal reflux disease

PCDHA4 PCDHA3 PCDHA2 PCDHA1

5.60e-04228494EFO_0003948, MONDO_0004975
Diseasetemporal lobe epilepsy (biomarker_via_orthology)

CYFIP1 VDAC2

1.22e-0331492DOID:3328 (biomarker_via_orthology)
DiseaseComplement deficiency disease

THBD CD46

1.38e-0333492C0272242
Diseaseasthma (implicated_via_orthology)

CCL26 ITGB6

1.55e-0335492DOID:2841 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RSQASQTDWCYDRTA

ERICH6B

271

Q5W0A0
WSACSASCSQGRQQR

ADGRB1

476

O14514
RTWYVQATCATQGTG

ARF5

151

P84085
TGYWSTQGCRLLTTN

ADGRL3

816

Q9HAR2
CSSAVGSWSYSQQRR

PCDHA9

741

Q9Y5H5
GSWSYSQQRRQRVCS

PCDHA9

746

Q9Y5H5
CSSAVGSWSYSQQRR

PCDHA2

741

Q9Y5H9
GSWSYSQQRRQRVCS

PCDHA2

746

Q9Y5H9
CSSAVGSWSYSQQRR

PCDHA6

741

Q9UN73
GSWSYSQQRRQRVCS

PCDHA6

746

Q9UN73
YRCRSGLSTGWTQLS

A1BG

91

P04217
CSSAVGSWSFSQQRR

PCDHA7

741

Q9UN72
RWTCTSSGSSPQYNI

CYFIP1

331

Q7L576
SRAVGSWSYSQQRRQ

PCDHA11

741

Q9Y5I1
CSSAVGSWSYSQQRQ

PCDHA3

741

Q9Y5H8
GSWSYSQQRQQRVCS

PCDHA3

746

Q9Y5H8
STIYCGDNSVWSRAA

CD46

206

P15529
WLGISCSSYERSSNA

NAB1

106

Q13506
QLSNWDTCSSRYPVS

MAPK4

346

P31152
RSGWTGEYCNCTTST

ITGB6

566

P18564
TTSETATWRRCANYV

MME

401

P08473
RYLGLVSCSATTQQW

NLRP2

786

Q9NX02
SSAVGSWSYSQQRRQ

PCDHA5

741

Q9Y5H7
SWSYSQQRRQRVCSG

PCDHA5

746

Q9Y5H7
DDRSGRWCSYSASNN

HUWE1

1621

Q7Z6Z7
RWCSYSASNNSTIDS

HUWE1

1626

Q7Z6Z7
CSSALGSWSNSQQRR

PCDHA1

741

Q9Y5I3
CSSAAGSWSYSQQRR

PCDHA13

741

Q9Y5I0
GSWSYSQQRRPRVCS

PCDHA13

746

Q9Y5I0
TLVCSSAVGSWSYSQ

PCDHA10

736

Q9Y5I2
SAVGSWSYSQQRRQR

PCDHA10

741

Q9Y5I2
CSSAVGSWSYSQQRR

PCDHA4

741

Q9UN74
GSWSYSQQRRPRVCS

PCDHA4

746

Q9UN74
TASSRRVCDSSGYWT

PAPPA2

896

Q9BXP8
CNWTIRATTGNTVNY

CUBN

1306

O60494
DPTSWYSSRSAYCRS

ATR

2446

Q13535
AFGAVRSVSYWNVSS

FASTKD5

21

Q7L8L6
RQSLLCTWGYSSNTR

FBXO7

31

Q9Y3I1
CTWGYSSNTRFTITL

FBXO7

36

Q9Y3I1
CASSYQRRWRRSQTT

FNIP1

281

Q8TF40
GTYSTTVTGRTCQAW

LPA

266

P08519
TYSTTVTGRTCQAWS

LPA

381

P08519
YSTTVTGRTCQAWSS

LPA

496

P08519
GTYSTTVTGRTCQAW

LPA

836

P08519
TYFITVTGRTCQAWS

LPA

951

P08519
YSTTVTGRTCQAWSS

LPA

1066

P08519
GLCGSRSSWVSDYSQ

DZANK1

561

Q9NVP4
NGSCKWSNNFIRSST

RNASE11

111

Q8TAA1
TRSNCGSRSFLWAQT

FAM87A

111

P0C7U9
CSSAVGSWSYSQQRR

PCDHA12

741

Q9UN75
GSWSYSQQRRQRVCS

PCDHA12

746

Q9UN75
SSQCRNWQDSSVSYA

MEMO1

276

Q9Y316
RSTCVQRATVSWLYG

OR14A16

136

Q8NHC5
AVCGSYSFTWSAART

FAM83G

266

A6ND36
TATVTGVRYQQSWLC

SLC4A11

186

Q8NBS3
SNTTYTTNSQCIRWV

ERVW-1

241

Q9UQF0
VTGDNNTSYSRWARL

THBD

111

P07204
SEWGTCSRNNRTCGF

RSPO2

151

Q6UXX9
SNSYWRIRGKSATVC

SDF2

66

Q99470
QDSQVYWTVACGSSR

TBC1D9B

66

Q66K14
RTWYVQATCATQGTG

ARF4

151

P18085
WVRSYEFTSNSCSQR

CCL26

46

Q9Y258
IWSSCRASRNTVNGY

SLC5A10

36

A0PJK1
TWYRSSRGEVQTCSE

VSIR

71

Q9H7M9
SVNLAWTSGTNCTRF

VDAC2

216

P45880
RCSSQSGHNTVSWYQ

TRBV5-4

41

A0A0C4DH59
CNSSSVFSSLQWYRQ

TRAV27

41

A0A087WT01
RSLSCCGVQNYTNWS

TSPAN7

146

P41732