Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-like protein ligase binding	TXNIP UBE2J2 CEBPB UBE2L6 UBE2G1 SMAD7	2.34e-05	358	33	6	GO:0044389
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	UBE2J2 UBE2L6 UBE2G1	3.08e-05	37	33	3	GO:0061631
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	UBE2J2 UBE2L6 UBE2G1	4.85e-05	43	33	3	GO:0061650
GeneOntologyMolecularFunction	ubiquitin protein ligase binding	TXNIP UBE2J2 UBE2L6 UBE2G1 SMAD7	2.14e-04	337	33	5	GO:0031625
GeneOntologyMolecularFunction	beta-catenin binding	CBY1 CDH13 SMAD7	1.01e-03	120	33	3	GO:0008013
MousePheno	abnormal adipose tissue amount	RALGAPA1 TXNIP PDS5B UBE2J2 CEBPB MYO15A CBY1 EPB41L1 ALG13	8.69e-05	1077	26	9	MP:0005452
MousePheno	abnormal adipose tissue morphology	RALGAPA1 TXNIP PDS5B UBE2J2 CEBPB MYO15A CBY1 EPB41L1 LPP ALG13	9.13e-05	1361	26	10	MP:0000003
MousePheno	adipose tissue phenotype	RALGAPA1 TXNIP PDS5B UBE2J2 CEBPB MYO15A CBY1 EPB41L1 LPP ALG13	1.05e-04	1383	26	10	MP:0005375
Domain	UQ_con	UBE2J2 UBE2L6 UBE2G1	4.40e-05	39	33	3	PF00179
Domain	UBIQUITIN_CONJUGAT_1	UBE2J2 UBE2L6 UBE2G1	4.75e-05	40	33	3	PS00183
Domain	UBIQUITIN_CONJUGAT_2	UBE2J2 UBE2L6 UBE2G1	5.12e-05	41	33	3	PS50127
Domain	UBQ-conjugat_E2	UBE2J2 UBE2L6 UBE2G1	5.12e-05	41	33	3	IPR000608
Domain	-	UBE2J2 UBE2L6 UBE2G1	9.88e-05	51	33	3	3.10.110.10
Domain	UBQ-conjugating_enzyme/RWD	UBE2J2 UBE2L6 UBE2G1	1.11e-04	53	33	3	IPR016135
Domain	UBQ-conjugating_AS	UBE2L6 UBE2G1	8.85e-04	25	33	2	IPR023313
Domain	FERM_M	MYO15A EPB41L1	2.98e-03	46	33	2	PF00373
Domain	FERM_central	MYO15A EPB41L1	3.38e-03	49	33	2	IPR019748
Domain	FERM_domain	MYO15A EPB41L1	3.38e-03	49	33	2	IPR000299
Domain	FERM_1	MYO15A EPB41L1	3.52e-03	50	33	2	PS00660
Domain	FERM_2	MYO15A EPB41L1	3.52e-03	50	33	2	PS00661
Domain	Band_41_domain	MYO15A EPB41L1	3.52e-03	50	33	2	IPR019749
Domain	B41	MYO15A EPB41L1	3.52e-03	50	33	2	SM00295
Domain	FERM_3	MYO15A EPB41L1	3.52e-03	50	33	2	PS50057
Domain	SH3_2	MYO15A SH3D19	1.01e-02	86	33	2	IPR011511
Domain	SH3_2	MYO15A SH3D19	1.01e-02	86	33	2	PF07653
Pathway	KEGG_PARKINSONS_DISEASE	CYC1 UBA1 UBE2J2 UBE2L6 UBE2G1 NDUFB7	1.75e-07	130	28	6	M7272
Pathway	WP_PARKINSONS_DISEASE	UBA1 UBE2J2 UBE2L6 UBE2G1	4.57e-06	57	28	4	MM15899
Pathway	WP_PARKINSONS_DISEASE_PATHWAY	UBA1 UBE2J2 UBE2L6 UBE2G1	1.10e-05	71	28	4	M39461
Pathway	WP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY	UBA1 UBE2J2 UBE2L6 UBE2G1	1.10e-05	71	28	4	M39690
Pathway	KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS	UBA1 UBE2J2 UBE2L6 UBE2G1	1.38e-04	135	28	4	M15247
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	UBA1 UBE2J2 UBE2L6 UBE2G1 RBBP6	2.73e-04	299	28	5	MM15711
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	UBA1 UBE2J2 UBE2L6 UBE2G1 RBBP6	3.13e-04	308	28	5	M1070
Pathway	REACTOME_PROTEIN_UBIQUITINATION	UBA1 UBE2J2 UBE2G1	5.02e-04	79	28	3	M27742
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	UBA1 UBE2J2 UBE2L6 UBE2G1 RBBP6	5.13e-04	343	28	5	MM15712
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	UBA1 UBE2J2 UBE2L6 UBE2G1 RBBP6	8.27e-04	381	28	5	M1066
Pathway	WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE	CEBPB PRDM16	1.11e-03	25	28	2	M39665
Pathway	REACTOME_SYNTHESIS_OF_ACTIVE_UBIQUITIN_ROLES_OF_E1_AND_E2_ENZYMES	UBA1 UBE2G1	1.60e-03	30	28	2	M27762
Pathway	REACTOME_SYNTHESIS_OF_ACTIVE_UBIQUITIN_ROLES_OF_E1_AND_E2_ENZYMES	UBA1 UBE2G1	1.60e-03	30	28	2	MM15507
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 MEGF8 ATXN1 EPB41L1 SH3D19 LPP PAK4 AHNAK2	1.10e-06	861	33	8	36931259
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	AUTS2 PDS5B CEBPB PRPF8 RBBP6 CBY1 AMOTL1 SMAD7	1.82e-06	922	33	8	27609421
Pubmed	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.	UBE2J2 UBE2L6 UBE2G1	1.99e-06	26	33	3	20061386
Pubmed	Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay.	UBA1 UBE2L6 UBE2G1	2.24e-06	27	33	3	30097011
Pubmed	Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.	CEBPB PRDM16	2.62e-06	3	33	2	28854265
Pubmed	Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s).	UBE2J2 UBE2G1	2.62e-06	3	33	2	11278356
Pubmed	Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor.	UBE2J2 UBE2G1	5.23e-06	4	33	2	8393731
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CEBPB SNAPC4 MEGF8 LARS2 PRDM16 ZDHHC8 AHNAK2 SMAD7	6.93e-06	1105	33	8	35748872
Pubmed	PPARγ and C/EBPα response to acute cold stress in brown adipose tissue.	TXNIP CEBPB	8.72e-06	5	33	2	36624847
Pubmed	Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.	UBE2L6 UBE2G1	8.72e-06	5	33	2	10558980
Pubmed	A muscle-specific MuRF1-E2 network requires stabilization of MuRF1-E2 complexes by telethonin, a newly identified substrate.	UBE2J2 UBE2G1	1.31e-05	6	33	2	29271608
Pubmed	PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.	PRDM16 SMAD7	1.31e-05	6	33	2	17467076
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	PRPF8 LARS2 CBY1 AMOTL1 AHNAK2	1.47e-05	332	33	5	37433992
Pubmed	Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity.	UBA1 UBE2L6	1.83e-05	7	33	2	9153201
Pubmed	The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1.	UBE2L6 UBE2G1	1.83e-05	7	33	2	10521492
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	UBA1 PRPF8 RBBP6 SH3D19 LPP PAK4 AHNAK2	2.29e-05	934	33	7	33916271
Pubmed	Prdm16 is required for normal palatogenesis in mice.	PRDM16 SMAD7	3.13e-05	9	33	2	20007998
Pubmed	Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.	UBA1 UBE2G1	3.13e-05	9	33	2	30279270
Pubmed	Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression.	CEBPB PRDM16	3.91e-05	10	33	2	22859371
Pubmed	A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.	CYC1 SNAPC4 UBE2L6 PRPF8 RBBP6	4.45e-05	419	33	5	28700943
Pubmed	HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.	UBA1 UBE2J2 UBE2G1	8.64e-05	90	33	3	35671810
Pubmed	Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.	UBE2L6 UBE2G1	9.10e-05	15	33	2	21628527
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	PDS5B SNAPC4 ATXN1 PRDM16 LPP SMAD7	1.00e-04	808	33	6	20412781
Pubmed	Rb regulates fate choice and lineage commitment in vivo.	CEBPB PRDM16	1.04e-04	16	33	2	20686481
Pubmed	RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.	UBE2G1 SMAD7	1.18e-04	17	33	2	28292929
Pubmed	Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.	CEBPB PRDM16	1.18e-04	17	33	2	26963625
Pubmed	Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method.	UBA1 UBE2J2	1.18e-04	17	33	2	36563856
Pubmed	A multifunctional protein, EWS, is essential for early brown fat lineage determination.	CEBPB PRDM16	1.48e-04	19	33	2	23987512
Pubmed	Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development.	CEBPB PRDM16	1.48e-04	19	33	2	25848030
Pubmed	Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.	UBA1 UBE2J2	1.48e-04	19	33	2	27425610
Pubmed	Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.	CEBPB PRDM16	1.48e-04	19	33	2	19641492
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	UBA1 RBBP6 SH3D19 AMOTL1 LPP	1.59e-04	549	33	5	38280479
Pubmed	Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.	UBA1 CEBPB	2.18e-04	23	33	2	22573614
Pubmed	E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.	UBA1 UBE2L6	2.18e-04	23	33	2	19250909
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	PDS5B UBA1 LPP PAK4	2.20e-04	315	33	4	26777405
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	UBA1 MEGF8 ATXN1 CBY1 ALG13	2.54e-04	608	33	5	16713569
Pubmed	PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.	LARS2 PAK4 ALG13	2.56e-04	130	33	3	26598620
Pubmed	SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation.	CEBPB PRDM16	2.58e-04	25	33	2	31433978
Pubmed	Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging.	UBA1 UBE2G1	2.58e-04	25	33	2	17597759
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PDS5B UBA1 CEBPB MYO15A PRPF8 RBBP6	3.42e-04	1014	33	6	32416067
Pubmed	Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes.	CEBPB PRDM16	3.49e-04	29	33	2	38972757
Pubmed	Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.	UBE2J2 UBE2L6 UBE2G1	3.83e-04	149	33	3	19549727
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALGAPA1 UBA1 EPB41L1 SH3D19 PAK4	5.10e-04	708	33	5	39231216
Pubmed	The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation.	CEBPB PRDM16	5.69e-04	37	33	2	35863637
Pubmed	Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development.	CEBPB PRDM16	5.69e-04	37	33	2	23907538
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	CYC1 UBA1 PRPF8 AHNAK2	6.62e-04	422	33	4	27342126
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RALGAPA1 AMOTL1 PAK4 ALG13	8.13e-04	446	33	4	24255178
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	PDS5B PRPF8 RBBP6	8.37e-04	195	33	3	19454010
Pubmed	Huntingtin interacting proteins are genetic modifiers of neurodegeneration.	CYC1 CDH13 EPB41L1	8.62e-04	197	33	3	17500595
Interaction	YWHAH interactions	RALGAPA1 UBA1 CEBPB MEGF8 ATXN1 CBY1 EPB41L1 SH3D19 LPP PAK4 AHNAK2	7.90e-07	1102	33	11	int:YWHAH
Interaction	YWHAZ interactions	RALGAPA1 UBA1 CEBPB UBE2L6 PRPF8 ATXN1 CBY1 EPB41L1 SH3D19 AMOTL1 PAK4	4.58e-06	1319	33	11	int:YWHAZ
Interaction	YWHAQ interactions	RALGAPA1 CEBPB UBE2L6 PRPF8 LARS2 ATXN1 CBY1 EPB41L1 SH3D19 PAK4	7.60e-06	1118	33	10	int:YWHAQ
Interaction	ATP5MF interactions	CYC1 PRDM16 NDUFB7 AMOTL1 LPP	9.60e-06	177	33	5	int:ATP5MF
Interaction	SFN interactions	RALGAPA1 CEBPB PRPF8 ATXN1 CBY1 SH3D19 PAK4 AHNAK2	1.20e-05	692	33	8	int:SFN
Interaction	ZYX interactions	CEBPB ATXN1 SH3D19 LPP AHNAK2 ALG13	1.38e-05	329	33	6	int:ZYX
Interaction	YWHAG interactions	RALGAPA1 UBA1 CEBPB UBE2L6 ATXN1 CBY1 EPB41L1 SH3D19 PAK4 AHNAK2	1.99e-05	1248	33	10	int:YWHAG
Interaction	ITCH interactions	TXNIP UBA1 UBE2J2 UBE2L6 UBE2G1 SMAD7	2.16e-05	356	33	6	int:ITCH
Interaction	EZR interactions	UBA1 CEBPB PRPF8 EPB41L1 SH3D19 LPP PAK4	2.59e-05	553	33	7	int:EZR
Interaction	UBA1 interactions	UBA1 UBE2J2 CEBPB UBE2L6 UBE2G1 ATXN1	3.11e-05	380	33	6	int:UBA1
Interaction	ATP1A1 interactions	CYC1 TXNIP CEBPB UBE2L6 PRPF8 ATXN1 PRDM16	3.32e-05	575	33	7	int:ATP1A1
Interaction	ATP5PB interactions	CYC1 CEBPB ATXN1 PRDM16 NDUFB7 EPB41L1	3.35e-05	385	33	6	int:ATP5PB
Interaction	GPATCH8 interactions	CEBPB ATXN1 EPB41L1 ALG13	3.62e-05	115	33	4	int:GPATCH8
Interaction	WWP2 interactions	TXNIP UBE2J2 UBE2L6 UBE2G1 PRPF8 SH3D19 AMOTL1 SMAD7	4.83e-05	840	33	8	int:WWP2
Interaction	SDHB interactions	CYC1 CEBPB LARS2 ATXN1 NDUFB7	5.14e-05	251	33	5	int:SDHB
Interaction	CTPS1 interactions	TXNIP UBA1 CEBPB PRPF8 ATXN1	5.24e-05	252	33	5	int:CTPS1
Interaction	PRPS2 interactions	PDS5B SNAPC4 ATXN1 CBY1 ALG13	5.34e-05	253	33	5	int:PRPS2
Interaction	TNIP2 interactions	AUTS2 PDS5B CEBPB PRPF8 RBBP6 CBY1 AMOTL1 SMAD7	1.16e-04	952	33	8	int:TNIP2
Interaction	YWHAE interactions	RALGAPA1 UBA1 CEBPB ATXN1 CBY1 EPB41L1 SH3D19 AMOTL1 PAK4	1.36e-04	1256	33	9	int:YWHAE
Interaction	LYN interactions	DUOXA1 PRPF8 ZDHHC8 EPB41L1 SH3D19 PAK4 AHNAK2	1.37e-04	720	33	7	int:LYN
Interaction	IDH3A interactions	CYC1 CEBPB ATXN1 NDUFB7	1.41e-04	163	33	4	int:IDH3A
Interaction	DDX41 interactions	CEBPB PRPF8 ATXN1 CBY1	1.51e-04	166	33	4	int:DDX41
Interaction	DCP1A interactions	CEBPB UBE2L6 CBY1 LPP	1.51e-04	166	33	4	int:DCP1A
Interaction	RHOU interactions	RALGAPA1 LARS2 ZDHHC8 EPB41L1 PAK4 ALG13	1.58e-04	510	33	6	int:RHOU
Interaction	NEDD4L interactions	TXNIP UBE2J2 UBE2L6 AMOTL1 SMAD7	1.61e-04	320	33	5	int:NEDD4L
Interaction	KPNA2 interactions	TXNIP UBA1 CEBPB PRPF8 ATXN1 PRDM16	1.74e-04	519	33	6	int:KPNA2
Interaction	YWHAB interactions	RALGAPA1 CEBPB ATXN1 CBY1 EPB41L1 SH3D19 PAK4 AHNAK2	1.80e-04	1014	33	8	int:YWHAB
Interaction	PDHB interactions	CYC1 CEBPB ATXN1 PRDM16 NDUFB7	2.19e-04	342	33	5	int:PDHB
Interaction	NDUFA9 interactions	CYC1 PRPF8 ATXN1 PRDM16 NDUFB7	2.41e-04	349	33	5	int:NDUFA9
Interaction	SLC3A2 interactions	TXNIP CEBPB PRPF8 ATXN1 PRDM16	3.24e-04	372	33	5	int:SLC3A2
Interaction	NDUFA10 interactions	CYC1 CEBPB LARS2 NDUFB7	3.31e-04	204	33	4	int:NDUFA10
Interaction	TLE3 interactions	AUTS2 CEBPB ATXN1 RBBP6 ALG13	3.40e-04	376	33	5	int:TLE3
Interaction	RHOB interactions	RALGAPA1 PDS5B UBA1 ZDHHC8 EPB41L1 SH3D19 PAK4	3.52e-04	840	33	7	int:RHOB
Interaction	COPS4 interactions	CEBPB PRPF8 ATXN1 EPB41L1	3.57e-04	208	33	4	int:COPS4
Interaction	UHRF1 interactions	CEBPB PRPF8 ATXN1 PRDM16	3.57e-04	208	33	4	int:UHRF1
Interaction	ABCF2 interactions	CEBPB UBE2L6 ATXN1 PRDM16	3.63e-04	209	33	4	int:ABCF2
Interaction	LARS1 interactions	UBA1 CEBPB PRPF8 LARS2 ATXN1	3.70e-04	383	33	5	int:LARS1
Interaction	MEX3A interactions	PRPF8 LARS2 CBY1 AMOTL1 AHNAK2	3.74e-04	384	33	5	int:MEX3A
Interaction	GSC interactions	AUTS2 ATXN1 PRDM16	3.86e-04	87	33	3	int:GSC
Interaction	GGNBP2 interactions	ATXN1 PAK4	3.91e-04	18	33	2	int:GGNBP2
Interaction	JMJD1C interactions	TXNIP ATXN1 ALG13	3.99e-04	88	33	3	int:JMJD1C
Interaction	PLRG1 interactions	CEBPB PRPF8 ATXN1 PRDM16	4.12e-04	216	33	4	int:PLRG1
Interaction	RCC2 interactions	CEBPB PRPF8 ATXN1 PAK4	4.19e-04	217	33	4	int:RCC2
Interaction	HDAC2 interactions	TXNIP CEBPB UBE2L6 PRDM16 LPP AHNAK2 SMAD7	4.20e-04	865	33	7	int:HDAC2
Interaction	UQCR10 interactions	CYC1 ATXN1 NDUFB7	4.69e-04	93	33	3	int:UQCR10
Interaction	GATAD2A interactions	CEBPB ATXN1 PRDM16 PAK4	4.72e-04	224	33	4	int:GATAD2A
Interaction	AP1M1 interactions	UBA1 CEBPB ATXN1 PRDM16	4.88e-04	226	33	4	int:AP1M1
Interaction	DDX46 interactions	TXNIP CEBPB PRPF8 ATXN1	4.96e-04	227	33	4	int:DDX46
Interaction	BUB3 interactions	UBA1 CEBPB PRPF8 ATXN1	5.39e-04	232	33	4	int:BUB3
Interaction	RHOG interactions	CYC1 RALGAPA1 LARS2 ZDHHC8 EPB41L1 PAK4 AHNAK2	5.70e-04	910	33	7	int:RHOG
Interaction	USP9X interactions	TXNIP PRPF8 ATXN1 AMOTL1 PAK4	5.75e-04	422	33	5	int:USP9X
Interaction	RNPS1 interactions	CEBPB PRPF8 ATXN1 RBBP6 EPB41L1	5.94e-04	425	33	5	int:RNPS1
Interaction	U2AF1 interactions	CEBPB PRPF8 ATXN1 ALG13	6.02e-04	239	33	4	int:U2AF1
Interaction	LARP4B interactions	CEBPB ATXN1 RBBP6 ALG13	6.12e-04	240	33	4	int:LARP4B
Interaction	BRD2 interactions	AUTS2 CEBPB LARS2 ATXN1 EPB41L1	6.20e-04	429	33	5	int:BRD2
Interaction	GTF2A1 interactions	CEBPB SNAPC4 ATXN1	6.51e-04	104	33	3	int:GTF2A1
Interaction	HERC5 interactions	UBA1 UBE2J2 UBE2L6 UBE2G1	6.61e-04	245	33	4	int:HERC5
Interaction	TAF10 interactions	CEBPB SNAPC4 ATXN1	7.07e-04	107	33	3	int:TAF10
Interaction	KRT17 interactions	CYC1 UBA1 CEBPB ATXN1	7.34e-04	252	33	4	int:KRT17
Interaction	RBM10 interactions	TXNIP PDS5B CEBPB ATXN1	7.45e-04	253	33	4	int:RBM10
Interaction	FKBP11 interactions	CEBPB AHNAK2	7.62e-04	25	33	2	int:FKBP11
Interaction	CSNK2A1 interactions	TXNIP AUTS2 SNAPC4 PRPF8 ATXN1 PRDM16 AMOTL1	7.64e-04	956	33	7	int:CSNK2A1
GeneFamily	Ubiquitin conjugating enzymes E2	UBE2J2 UBE2L6 UBE2G1	1.40e-05	41	21	3	102
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO15A EPB41L1	1.52e-03	50	21	2	1293
Coexpression	MEK_UP.V1_DN	RALGAPA1 AUTS2 UBE2L6 SMAD7 ALG13	4.23e-06	194	33	5	M2724
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	CYC1 TXNIP CEBPB UBE2L6 PRDM16 EPB41L1 SH3D19 AMOTL1 LPP	1.99e-05	1276	33	9	M39173
Coexpression	ENK_UV_RESPONSE_KERATINOCYTE_UP	CYC1 UBA1 CEBPB NDUFB7 RBBP6 SMAD7	4.77e-05	533	33	6	M10791
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	RALGAPA1 TXNIP AUTS2 PDS5B UBE2L6 PRPF8 ATXN1 RBBP6 SMAD7	6.80e-05	1492	33	9	M40023
Coexpression	GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP	AUTS2 RBBP6 LPP SMAD7	1.09e-04	198	33	4	M5774
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN	CYC1 SNAPC4 SH3D19 SMAD7	1.11e-04	199	33	4	M7319
Coexpression	GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_DN	TXNIP UBE2L6 CBY1 SMAD7	1.11e-04	199	33	4	M5242
Coexpression	GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN	AUTS2 ATXN1 LPP SMAD7	1.13e-04	200	33	4	M4659
Coexpression	GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN	AUTS2 ATXN1 LPP SMAD7	1.13e-04	200	33	4	M4656
Coexpression	GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_UP	AUTS2 PRPF8 CDH13 AMOTL1	1.13e-04	200	33	4	M8469
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	TXNIP SNX31 CEBPB ATXN1	1.13e-04	200	33	4	M9190
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN	PDS5B ATXN1 SMAD7	1.62e-04	84	33	3	M13008
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP UBA1 LARS2 SH3D19 LPP	3.20e-07	196	33	5	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP UBA1 LARS2 SH3D19 LPP	3.20e-07	196	33	5	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	Somatosensory_Cortex_(S1)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AUTS2 ATXN1 CDH13 LPP	9.06e-06	179	33	4	82348bf56a4525b2f485696cab5b2ea6e96c2f91
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPB SNAPC4 AMOTL1 LPP	1.03e-05	185	33	4	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPB SNAPC4 AMOTL1 LPP	1.03e-05	185	33	4	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TXNIP CDH13 LPP AHNAK2	1.05e-05	186	33	4	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP PRPF8 LARS2 CDH13	1.10e-05	188	33	4	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP DUOXA1 CDH13 LPP	1.29e-05	196	33	4	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Thalamus / BrainAtlas - Mouse McCarroll V32	AUTS2 AMOTL1 AHNAK2	5.54e-05	100	33	3	1de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Thalamus / BrainAtlas - Mouse McCarroll V32	AUTS2 AMOTL1 AHNAK2	5.54e-05	100	33	3	20675fc2ffc5ab63047d38da083b50d470f3db19
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora\|Thalamus / BrainAtlas - Mouse McCarroll V32	AUTS2 AMOTL1 AHNAK2	5.54e-05	100	33	3	ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RALGAPA1 CDH13 LPP	2.35e-04	163	33	3	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	AUTS2 DUOXA1 PRDM16	2.35e-04	163	33	3	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PRDM16 CDH13 LPP	2.80e-04	173	33	3	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CBY1 LPP AHNAK2	2.95e-04	176	33	3	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	facs\|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARS2 ATXN1 CDH13	3.09e-04	179	33	3	8001db3044e8657980e24422377c4fdb0d7b323e
ToppCell	LV\|World / Chamber and Cluster_Paper	TXNIP PRDM16 CDH13	3.15e-04	180	33	3	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	RV\|World / Chamber and Cluster_Paper	TXNIP PRDM16 CDH13	3.20e-04	181	33	3	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RALGAPA1 ATXN1 LPP	3.20e-04	181	33	3	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	LA-07._Pericyte\|World / Chamber and Cluster_Paper	SNX31 EPB41L1 LPP	3.30e-04	183	33	3	e3835db4795362b0442d5893baf2a78efcc20428
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	TXNIP UBE2L6 RBBP6	3.30e-04	183	33	3	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPB LARS2 SMAD7	3.46e-04	186	33	3	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRDM16 EPB41L1 SH3D19	3.52e-04	187	33	3	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	COPD-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	PRDM16 CDH13 LPP	3.57e-04	188	33	3	9ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRDM16 EPB41L1 SH3D19	3.63e-04	189	33	3	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	TXNIP PRDM16 CDH13	3.63e-04	189	33	3	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPB LARS2 SMAD7	3.63e-04	189	33	3	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	AUTS2 PRDM16 LPP	3.68e-04	190	33	3	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	COPD-Lymphoid-T_Cytotoxic\|Lymphoid / Disease state, Lineage and Cell class	RALGAPA1 AUTS2 ATXN1	3.68e-04	190	33	3	10bece40d980d37a01dae8ce887655bf9f93040c
ToppCell	Control-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	PRDM16 CDH13 LPP	3.74e-04	191	33	3	2da83c493e60ad0278848957645277d76737a188
ToppCell	control-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DEXI CBY1 EPB41L1	3.74e-04	191	33	3	afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AUTS2 DUOXA1 PRDM16	3.74e-04	191	33	3	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPB LARS2 SMAD7	3.74e-04	191	33	3	2f733d510a4862565a817f59829d8387d7ea26d9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDS5B ATXN1 CDH13	3.74e-04	191	33	3	1caf726bd07fdca389e678fc16304a6ef1790423
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPB LARS2 SMAD7	3.74e-04	191	33	3	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CDH13 EPB41L1 AHNAK2	3.74e-04	191	33	3	5ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDS5B ATXN1 CDH13	3.74e-04	191	33	3	3d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AUTS2 ATXN1 CDH13	3.80e-04	192	33	3	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	IPF-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	PRDM16 CDH13 LPP	3.80e-04	192	33	3	9b06c7336624ef21f8e5393725b56038a8028e57
ToppCell	COPD-Lymphoid-T_Cytotoxic\|World / Disease state, Lineage and Cell class	RALGAPA1 AUTS2 ATXN1	3.80e-04	192	33	3	5bfd9f5d47511441eb2d3cc3c4d7ed330ffd0bd1
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	AUTS2 DUOXA1 PRDM16	3.80e-04	192	33	3	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AUTS2 ATXN1 CDH13	3.80e-04	192	33	3	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	mild_COVID-19-gd_T\|World / disease group, cell group and cell class (v2)	RALGAPA1 AUTS2 SMAD7	3.80e-04	192	33	3	6912283dbd73285b6e0c653b2dd34c31337b9f1e
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ATXN1 SH3D19 LPP	3.80e-04	192	33	3	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	AUTS2 CDH13 EPB41L1	3.86e-04	193	33	3	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	COPD-Lymphoid-T_Cytotoxic\|COPD / Disease state, Lineage and Cell class	RALGAPA1 AUTS2 ATXN1	3.86e-04	193	33	3	58e94fe2e89cdafc6974938f97a4c162061a437d
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TXNIP LPP AHNAK2	3.86e-04	193	33	3	b1893193766ae41bf2ab6ed4083285c9c814e608
ToppCell	facs-Skin-Telogen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP CDH13 LPP	3.92e-04	194	33	3	ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH13 AMOTL1 SMAD7	3.92e-04	194	33	3	c8b9551b93a5aed62154b487db90130604a6125c
ToppCell	facs-Skin-Telogen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP CDH13 LPP	3.92e-04	194	33	3	4d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCell	facs-Skin-Telogen\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP CDH13 LPP	3.92e-04	194	33	3	bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCell	10x5'-blood-Lymphocytic_NK\|blood / Manually curated celltypes from each tissue	AUTS2 CEBPB SMAD7	3.97e-04	195	33	3	c1db871e8e8e8b8d6a5798bc43eaf54e102b75eb
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOXA1 NDUFB7 CDH13	3.97e-04	195	33	3	0be50d5bd0bef2240f7ace8056ce22a6ca2961b9
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	AUTS2 ATXN1 LPP	4.03e-04	196	33	3	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	droplet-Tongue-TONGUE\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP CEBPB AMOTL1	4.03e-04	196	33	3	44a30b1a5f3d8c845e5f3bd17d8102a7449f555b
ToppCell	droplet-Tongue-TONGUE-1m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP CEBPB AMOTL1	4.03e-04	196	33	3	9935bdb10789e8cfc922dca526ca3bf8317fe270
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP DUOXA1 CDH13	4.03e-04	196	33	3	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	P15-Mesenchymal-myocytic_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CEBPB CDH13 LPP	4.03e-04	196	33	3	41ae5b0d81ad09a6663335d899b4a1e4976c3b62
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP CEBPB AMOTL1	4.03e-04	196	33	3	a85f5f1e6acc798e9e02b1a21e0ffe87a323c333
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP ATXN1 AMOTL1	4.03e-04	196	33	3	d4df86ce289835e76763213641989fde77935a16
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC\|World / Primary Cells by Cluster	CYC1 AUTS2 UBE2J2	4.09e-04	197	33	3	2c3b0072f8e1e09c77a85c6fc3133d1796932fb2
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CDH13 LPP AHNAK2	4.09e-04	197	33	3	4e0c3ea4f4a04a41532806edf3bccf7845c86fa5
ToppCell	facs-Heart-RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP SH3D19 SMAD7	4.09e-04	197	33	3	940cf1e54d7c820e04946258a8b784f35c6a144c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC-29\|World / Primary Cells by Cluster	CYC1 AUTS2 UBE2J2	4.09e-04	197	33	3	c5bc0e7eb85642b270efc2ba92b13a736af22052
ToppCell	367C-Myeloid-Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TXNIP UBE2L6 NDUFB7	4.09e-04	197	33	3	f5c21f0d363b5c298a2b82f6dff4f369397b5f25
ToppCell	Bronchial_Brush-Epithelial-Basal_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SNX31 CDH13 AMOTL1	4.09e-04	197	33	3	f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCell	tumor_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	RALGAPA1 SMAD7 ALG13	4.09e-04	197	33	3	dcce1c3dc5f3e53c368f758eb0fd5afcd86325e7
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	AUTS2 ATXN1 LPP	4.16e-04	198	33	3	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	PRDM16 CDH13 LPP	4.16e-04	198	33	3	89986c7756541df364df516329d10775ba0e78a4
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SNX31 DUOXA1 AHNAK2	4.16e-04	198	33	3	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	PBMC-Mild-cDC_0\|Mild / Compartment, Disease Groups and Clusters	CEBPB ATXN1 SMAD7	4.16e-04	198	33	3	fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SNX31 DUOXA1 CDH13	4.16e-04	198	33	3	5374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DUOXA1 EPB41L1 SH3D19	4.16e-04	198	33	3	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	AUTS2 ATXN1 LPP	4.22e-04	199	33	3	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CDH13 AMOTL1 LPP	4.22e-04	199	33	3	a207b4891881149d4c50721310690fd794157723
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TXNIP AUTS2 SMAD7	4.22e-04	199	33	3	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	PBMC-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	CEBPB ATXN1 SMAD7	4.22e-04	199	33	3	ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell	3'-GW_trimst-1.5-SmallIntestine\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TXNIP UBE2L6 NDUFB7	4.22e-04	199	33	3	7d853204ec84b7ea716556207223be18b6c3754e
ToppCell	COVID_vent-Lymphocytic-ILC-NK_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TXNIP AUTS2 SMAD7	4.22e-04	199	33	3	5f914962e2572b0c6372465b81b7496fa663d93c
ToppCell	(2)_Fibroblasts-(24)_Fibro-5\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	DUOXA1 CDH13 AHNAK2	4.22e-04	199	33	3	6c0354f57883330c685a8d9d5d3014ace7eca584
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	AUTS2 CDH13 AMOTL1	4.28e-04	200	33	3	347a510755374c6a66acee326565dfc447993f18
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DUOXA1 EPB41L1 AHNAK2	4.28e-04	200	33	3	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TXNIP CEBPB UBE2L6	4.28e-04	200	33	3	0d3f4097fc07606791feb71e86e0df07231990d7
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	TXNIP UBE2L6 SMAD7	4.28e-04	200	33	3	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	TXNIP CEBPB NDUFB7	4.28e-04	200	33	3	bffebc281a5c1c2bfdb2696a45343787289fc374
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DUOXA1 EPB41L1 AHNAK2	4.28e-04	200	33	3	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	TXNIP AUTS2 SMAD7	4.28e-04	200	33	3	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
Disease	orofacial cleft, sex interaction measurement	CDH13 AMOTL1 LPP	1.22e-04	86	33	3	EFO_0008343, MONDO_0000358
Disease	non-melanoma skin carcinoma	MYO15A EPB41L1 AMOTL1 LPP	2.12e-04	265	33	4	EFO_0009260
Disease	hearing threshold measurement	AUTS2 CDH13	4.50e-04	28	33	2	EFO_0007618
Disease	glucose measurement	AUTS2 CEBPB MEGF8 PRDM16	8.25e-04	380	33	4	EFO_0004468
Disease	basal cell carcinoma	MYO15A EPB41L1 LPP	1.22e-03	189	33	3	EFO_0004193
Disease	mean corpuscular hemoglobin concentration	CYC1 PDS5B MYO15A ATXN1 PRDM16 SMAD7	1.27e-03	1105	33	6	EFO_0004528
Disease	motion sickness	AUTS2 PRDM16	1.32e-03	48	33	2	EFO_0006928
Disease	asthma	PDS5B PRDM16 SH3D19 LPP SMAD7	1.39e-03	751	33	5	MONDO_0004979
Disease	monoclonal gammopathy	AUTS2 CDH13	1.61e-03	53	33	2	EFO_0000203
Disease	waist-hip ratio	SNX31 CEBPB UBE2G1 MEGF8 PRDM16 CDH13	2.15e-03	1226	33	6	EFO_0004343
Disease	fish consumption measurement	ATXN1 CDH13	2.34e-03	64	33	2	EFO_0010139
Disease	serum IgE measurement	CDH13 LPP	2.34e-03	64	33	2	EFO_0004579
Disease	squamous cell carcinoma	EPB41L1 LPP	2.56e-03	67	33	2	EFO_0000707
Disease	Epilepsy, Cryptogenic	AUTS2 ALG13	3.81e-03	82	33	2	C0086237
Disease	Awakening Epilepsy	AUTS2 ALG13	3.81e-03	82	33	2	C0751111
Disease	Aura	AUTS2 ALG13	3.81e-03	82	33	2	C0236018
Disease	hypothyroidism	UBE2J2 CDH13 LPP	3.89e-03	284	33	3	EFO_0004705
Disease	Alveolitis, Fibrosing	CEBPB SMAD7	3.90e-03	83	33	2	C4721507
Disease	Pulmonary Fibrosis	CEBPB SMAD7	4.09e-03	85	33	2	C0034069
Disease	Eczema	PRDM16 LPP SMAD7	4.96e-03	310	33	3	HP_0000964
Disease	body surface area	RALGAPA1 AUTS2 CDH13 SMAD7	5.54e-03	643	33	4	EFO_0022196

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKSPENPSKMPFPYK	ALG13	441	Q9NP73
MPFFGNTFSPKKTPP	CBY1	1	Q9Y3M2
PRGPPPEYPFKTKQM	AMOTL1	306	Q8IY63
MRPGKLFDYFPKPYP	CYC1	166	P08574
APPTLPPYFMKGSII	ATXN1	566	P54253
PDKPSPNMFYIDPEK	CDH13	291	P55290
PPPLLPSMFYVGLFF	DEXI	21	O95424
YLPPEMKSFFTPGKP	PDS5B	1111	Q9NTI5
PPPKGFLVMGSKFRY	EPB41L1	381	Q9H4G0
NPLYSKPKMPLPEFT	MYO15A	1686	Q9UKN7
PPMFDKYPTKVDPFY	AUTS2	561	Q8WXX7
MAYKVPPFVFQAPAP	MEGF8	541	Q7Z7M0
NPPGMYPVTGPKKTY	LPP	341	Q93052
PGPKYLIPPTTGFMK	ODF3	26	Q96PU9
QMPTFPPDYGFPERK	NDUFB7	21	P17568
NYMKKPLGPPPPSYT	RBBP6	146	Q7Z6E9
PPPPAFKSMEVANFY	CEBPB	16	P17676
HTFPFYAGPKPTFPM	DUOXA1	6	Q1HG43
NLFPFPMKFPPTYSL	C3orf56	126	Q8N813
GEPPYFNEPPLKAMK	PAK4	511	O96013
PRPKPGHPLYSKYML	SH3D19	401	Q5HYK7
KPKFYVLSMFPYPSG	LARS2	81	Q15031
PPLHYAKPSPFFMDP	PRDM16	851	Q9HAZ2
LPPFPPKYYLAMTTA	SNX31	56	Q8N9S9
PKFKMPSYRASAPGK	AHNAK2	3311	Q8IVF2
KMPSRFPPVVFYTPK	PRPF8	1306	Q6P2Q9
SPPPPYSRYPMDFLK	SMAD7	206	O15105
MKKPEVPFFGPLFDG	RALGAPA1	1946	Q6GYQ0
SFPPEYPFKPPMIKF	UBE2L6	56	O14933
IFPREFPFKPPSIYM	UBE2J2	66	Q8N2K1
FPFKPPSIYMITPNG	UBE2J2	71	Q8N2K1
ATLPSPDKLPGFKMY	UBA1	831	P22314
TPAMYKFRPAFPTGP	ZDHHC8	351	Q9ULC8
MKPYFKDKVTGVGPP	SNAPC4	146	Q5SXM2
YAPEFKFMPPPTYTE	TXNIP	366	Q9H3M7
FPKDYPLRPPKMKFI	UBE2G1	61	P62253