Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA5 SPOCK2 VWF COL1A1

4.02e-05188214GO:0005201
GeneOntologyMolecularFunctionstructural molecule activity

KRTAP16-1 LAMA5 SPOCK2 VWF OTOG COL1A1

2.37e-04891216GO:0005198
GeneOntologyMolecularFunctionintegrin binding

LAMA5 ITGB3 VWF

7.84e-04175213GO:0005178
GeneOntologyMolecularFunctionprotease binding

ITGB3 VWF COL1A1

8.64e-04181213GO:0002020
GeneOntologyMolecularFunctionprotein kinase C binding

ITGB3 NELL2

2.17e-0366212GO:0005080
GeneOntologyMolecularFunctioncoreceptor activity

LRP4 ITGB3

2.58e-0372212GO:0015026
GeneOntologyMolecularFunctionextracellular matrix binding

ITGB3 SPOCK2

2.65e-0373212GO:0050840
GeneOntologyBiologicalProcesscell-substrate adhesion

LAMA5 ITGB3 SPOCK2 VWF COL1A1

3.67e-05410205GO:0031589
GeneOntologyCellularComponentkeratin filament

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

1.91e-1697219GO:0045095
GeneOntologyCellularComponentintermediate filament

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

4.70e-13227219GO:0005882
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

1.77e-12263219GO:0045111
GeneOntologyCellularComponentsupramolecular fiber

KRTAP16-1 AKAP13 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5 COL1A1

3.67e-0911792111GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRTAP16-1 AKAP13 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5 COL1A1

3.94e-0911872111GO:0099081
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRTAP16-1 AKAP13 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

4.72e-098992110GO:0099513
GeneOntologyCellularComponentextracellular matrix

LAMA5 SPOCK2 VWF OTOG COL1A1

4.02e-04656215GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA5 SPOCK2 VWF OTOG COL1A1

4.07e-04658215GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA5 SPOCK2 VWF COL1A1

1.73e-03530214GO:0062023
GeneOntologyCellularComponentplatelet alpha granule

ITGB3 VWF

3.89e-0393212GO:0031091
GeneOntologyCellularComponentneuromuscular junction

LRP4 LAMA5

5.59e-03112212GO:0031594
HumanPhenoProlonged bleeding time

ITGB3 VWF COL1A1

1.74e-055063HP:0003010
HumanPhenoAbnormality of skull ossification

LRP4 LAMA5 COL1A1

1.17e-049463HP:0002703
HumanPhenoProlonged bleeding after surgery

ITGB3 VWF

1.56e-041762HP:0004846
HumanPhenoDecreased calvarial ossification

LAMA5 COL1A1

1.56e-041762HP:0005474
HumanPhenoAbnormality of von Willebrand factor

ITGB3 VWF

2.64e-042262HP:0012146
HumanPhenoProlonged bleeding after dental extraction

ITGB3 VWF

2.89e-042362HP:0006298
MousePhenothick neurocranium

LRP4 COL1A1

1.03e-05892MP:0030278
MousePhenosyndactyly

LRP4 LAMA5 COL1A1

2.33e-059393MP:0000564
MousePhenoabnormal trabecular bone thickness

LRP4 ITGB3 COL1A1

2.72e-059893MP:0009345
MousePhenoabnormal extracellular matrix morphology

LAMA5 AKAP13 COL1A1

2.89e-0510093MP:0013258
MousePhenoabnormal tooth development

LRP4 LAMA5 COL1A1

3.64e-0510893MP:0000116
MousePhenoabnormal osteocyte morphology

LRP4 COL1A1

3.85e-051592MP:0008753
MousePhenoabnormal compact bone thickness

LRP4 ITGB3 COL1A1

5.24e-0512293MP:0000134
MousePhenoabnormal osteocyte lacunocanalicular system morphology

LRP4 COL1A1

5.61e-051892MP:0030485
MousePhenoreduced fertility

LRP4 ITGB3 AKAP13 OTOG COL1A1

8.15e-0584495MP:0001921
MousePhenoabnormal craniofacial development

LRP4 LAMA5 AKAP13 COL1A1

9.40e-0542594MP:0003935
MousePhenodecreased bone trabecular spacing

LRP4 COL1A1

1.01e-042492MP:0013631
MousePhenoabnormal compact bone morphology

LRP4 ITGB3 COL1A1

1.46e-0417293MP:0003797
MousePhenodecreased susceptibility to induced thrombosis

ITGB3 VWF

1.59e-043092MP:0031120
MousePhenooligodactyly

LRP4 COL1A1

2.70e-043992MP:0000565
MousePhenoabnormal chest morphology

LAMA5 COL1A1

2.70e-043992MP:0004134
MousePhenoimpaired branching involved in ureteric bud morphogenesis

LRP4 LAMA5

2.98e-044192MP:0004936
MousePhenoincreased compact bone thickness

LRP4 ITGB3

2.98e-044192MP:0004148
MousePhenodecreased cardiac muscle contractility

ITGB3 AKAP13 COL1A1

3.13e-0422393MP:0005140
MousePhenoincreased trabecular bone thickness

LRP4 ITGB3

3.28e-044392MP:0009347
MousePhenoabnormal branching involved in ureteric bud morphogenesis

LRP4 LAMA5

3.60e-044592MP:0010981
MousePhenoabnormal response to injury

ITGB3 AKAP13 VWF COL1A1

3.72e-0460794MP:0005164
MousePhenoabnormal bone trabecular spacing

LRP4 COL1A1

4.09e-044892MP:0013629
MousePhenoabsent kidney

LRP4 LAMA5

4.99e-045392MP:0000520
MousePhenoabnormal susceptibility to induced thrombosis

ITGB3 VWF

4.99e-045392MP:0020408
MousePhenorenal interstitial fibrosis

KCP LAMA5

5.18e-045492MP:0003215
MousePhenoabnormal hair follicle development

LRP4 LAMA5

5.18e-045492MP:0003704
MousePhenoabnormal neurocranium morphology

LRP4 LAMA5 COL1A1

5.43e-0426993MP:0000074
MousePhenoabnormal ureteric bud morphology

LRP4 LAMA5

5.77e-045792MP:0006032
MousePhenoabnormal trabecular bone morphology

LRP4 ITGB3 COL1A1

6.70e-0428993MP:0000130
MousePhenoabnormal tooth hard tissue morphology

LRP4 COL1A1

7.05e-046392MP:0003930
MousePhenoimpaired muscle contractility

ITGB3 AKAP13 COL1A1

7.25e-0429793MP:0000738
MousePhenoabnormal cardiac muscle contractility

ITGB3 AKAP13 COL1A1

7.61e-0430293MP:0002972
MousePhenodecreased heart left ventricle muscle contractility

AKAP13 COL1A1

7.74e-046692MP:0031633
MousePhenoabnormal kidney interstitium morphology

KCP LAMA5

7.97e-046792MP:0011425
MousePhenoabnormal tooth morphology

LRP4 LAMA5 COL1A1

8.85e-0431893MP:0002100
MousePhenoabnormal dental arch morphology

LRP4 LAMA5 COL1A1

8.93e-0431993MP:0030254
MousePhenoabnormal digit morphology

LRP4 LAMA5 COL1A1

9.26e-0432393MP:0002110
MousePhenoabnormal osteoclast physiology

ITGB3 COL1A1

9.46e-047392MP:0001541
MousePhenoabnormal bone strength

LRP4 COL1A1

9.72e-047492MP:0001542
MousePhenorenal fibrosis

KCP LAMA5

1.08e-037892MP:0003985
MousePhenoabnormal platelet activation

ITGB3 VWF

1.37e-038892MP:0006298
MousePhenoabnormal ureter morphology

LRP4 LAMA5

1.43e-039092MP:0000534
MousePhenoincreased bleeding time

ITGB3 VWF

1.46e-039192MP:0005606
MousePhenoabnormal kidney development

LRP4 LAMA5

1.53e-039392MP:0000527
MousePhenointernal hemorrhage

ITGB3 VWF COL1A1

1.56e-0338793MP:0001634
MousePhenoabnormal autopod morphology

LRP4 LAMA5 COL1A1

1.60e-0339093MP:0000572
MousePhenoabnormal tail morphology

LRP4 LAMA5 COL1A1

1.76e-0340393MP:0002111
MousePhenoenlarged heart

LAMA5 ITGB3 AKAP13 COL1A1

1.77e-0391694MP:0000274
MousePhenoabnormal muscle contractility

ITGB3 AKAP13 COL1A1

1.95e-0341893MP:0005620
MousePhenoabnormal thrombosis

ITGB3 VWF

1.98e-0310692MP:0005048
MousePhenodecreased heart ventricle muscle contractility

AKAP13 COL1A1

2.02e-0310792MP:0005598
MousePhenoabnormal response of heart to induced stress

ITGB3 AKAP13

2.09e-0310992MP:0004484
MousePhenoabnormal platelet physiology

ITGB3 VWF

2.13e-0311092MP:0005464
MousePhenoabnormal urinary system development

LRP4 LAMA5

2.17e-0311192MP:0003942
MousePhenoabnormal trabecular bone volume

LRP4 COL1A1

2.25e-0311392MP:0010877
MousePhenosmall lung

LRP4 LAMA5

2.33e-0311592MP:0003641
MousePhenoabnormal outer ear morphology

LAMA5 COL1A1

2.49e-0311992MP:0002177
MousePhenoabnormal ear morphology

LAMA5 OTOG COL1A1

2.73e-0347093MP:0002102
MousePhenoabnormal cardiac muscle tissue morphology

ITGB3 AKAP13 COL1A1

3.05e-0348993MP:0010630
MousePhenoabnormal bone trabecula morphology

LRP4 COL1A1

3.14e-0313492MP:0010867
MousePhenoabnormal osteoblast morphology

LRP4 COL1A1

3.28e-0313792MP:0004986
MousePhenoabnormal stationary movement

OTOG COL1A1

3.77e-0314792MP:0001388
MousePhenoabnormal hair follicle morphology

LRP4 LAMA5

3.82e-0314892MP:0000377
MousePhenoabnormal jaw morphology

LRP4 LAMA5 COL1A1

3.84e-0353093MP:0000454
DomainKAP

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

4.00e-1858219IPR002494
DomainKeratin_B2_2

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-12

1.11e-1439217PF13885
DomainKeratin_B2

KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-6 KRTAP10-12 KRTAP10-5

1.35e-1440217PF01500
DomainVWF_dom

KCP NELL2 VWF OTOG COL1A1

8.91e-1042215IPR001007
DomainVWC_out

KCP NELL2 VWF OTOG

4.53e-0919214SM00215
DomainVWC

KCP NELL2 VWF COL1A1

2.38e-0828214PF00093
DomainVWFC_1

KCP NELL2 VWF COL1A1

6.80e-0836214PS01208
DomainVWC

KCP NELL2 VWF COL1A1

8.50e-0838214SM00214
DomainVWFC_2

KCP NELL2 VWF COL1A1

8.50e-0838214PS50184
DomainC8

KCP VWF OTOG

3.48e-0713213SM00832
DomainUnchr_dom_Cys-rich

KCP VWF OTOG

3.48e-0713213IPR014853
DomainTIL_dom

KCP VWF OTOG

4.42e-0714213IPR002919
DomainVWFD

KCP VWF OTOG

6.80e-0716213PS51233
DomainVWD

KCP VWF OTOG

6.80e-0716213SM00216
DomainVWF_type-D

KCP VWF OTOG

6.80e-0716213IPR001846
DomainVWD

KCP VWF OTOG

6.80e-0716213PF00094
DomainTIL

VWF OTOG

7.89e-0512212PF01826
DomainC8

VWF OTOG

7.89e-0512212PF08742
DomainEGF-like_dom

LRP4 LAMA5 NELL2 OTOG

1.54e-04249214IPR000742
DomainEGF_1

LRP4 LAMA5 ITGB3 NELL2

1.69e-04255214PS00022
DomainEGF-like_CS

LRP4 LAMA5 ITGB3 NELL2

1.85e-04261214IPR013032
DomainEGF_2

LRP4 LAMA5 ITGB3 NELL2

1.96e-04265214PS01186
DomainCT

VWF OTOG

2.74e-0422212SM00041
DomainCys_knot_C

VWF OTOG

3.56e-0425212IPR006207
DomainCTCK_2

VWF OTOG

3.56e-0425212PS01225
DomainGrowth_fac_rcpt_

LRP4 LAMA5 NELL2

6.81e-04156213IPR009030
DomainLaminin_G_2

LAMA5 NELL2

9.15e-0440212PF02210
DomainLamG

LAMA5 NELL2

1.11e-0344212SM00282
DomainLaminin_G

LAMA5 NELL2

1.92e-0358212IPR001791
DomainEGF_extracell

ITGB3 NELL2

2.05e-0360212IPR013111
DomainEGF_2

ITGB3 NELL2

2.05e-0360212PF07974
DomainEGF

LRP4 LAMA5 NELL2

2.21e-03235213SM00181
DomainEGF_3

LRP4 NELL2 OTOG

2.21e-03235213PS50026
Domain-

ITGB3 VWF

3.10e-03742123.40.50.410
DomainVWFA

ITGB3 VWF

3.79e-0382212PS50234
DomainVWA

ITGB3 VWF

3.97e-0384212SM00327
DomainEGF_CA

LRP4 NELL2

4.16e-0386212PF07645
Domain-

LAMA5 NELL2

5.05e-03952122.60.120.200
DomainEGF_Ca-bd_CS

LRP4 NELL2

5.26e-0397212IPR018097
DomainVWF_A

ITGB3 VWF

5.47e-0399212IPR002035
DomainEGF_CA

LRP4 NELL2

5.47e-0399212PS01187
DomainASX_HYDROXYL

LRP4 NELL2

5.58e-03100212PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP4 NELL2

6.25e-03106212IPR000152
DomainEGF_CA

LRP4 NELL2

8.19e-03122212SM00179
DomainEGF-like_Ca-bd_dom

LRP4 NELL2

8.45e-03124212IPR001881
DomainEGF

LRP4 ITGB3

8.72e-03126212PF00008
PathwayREACTOME_KERATINIZATION

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

8.98e-13217179M27640
PathwayREACTOME_KERATINIZATION

KRTAP16-1 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

3.58e-12153178MM15343
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

KRTAP16-1 ITGB3 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

1.62e-09502179MM14537
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

KRTAP16-1 ITGB3 KRTAP10-9 NELL2 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

7.95e-0814321711M509
PathwayREACTOME_ECM_PROTEOGLYCANS

LRP4 LAMA5 ITGB3 COL1A1

1.76e-0676174M27219
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA5 ITGB3 VWF COL1A1

2.63e-0684174M7098
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

ITGB3 VWF COL1A1

1.20e-0538173MM15456
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

ITGB3 VWF COL1A1

1.30e-0539173M10735
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LRP4 LAMA5 ITGB3 VWF COL1A1

2.12e-05300175M610
PathwayREACTOME_ENHANCED_BINDING_OF_GP1BA_VARIANT_TO_VWF_MULTIMER_COLLAGEN

VWF COL1A1

2.86e-057172M48265
PathwayREACTOME_DEFECTS_OF_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN

VWF COL1A1

3.82e-058172M48236
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA5 ITGB3 COL1A1

4.54e-0559173M27218
PathwayWP_VITAMIN_D_RECEPTOR_PATHWAY

KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7

5.98e-05185174M39718
PathwayWP_FOCAL_ADHESION

LAMA5 ITGB3 VWF COL1A1

6.23e-05187174MM15913
PathwayKEGG_FOCAL_ADHESION

LAMA5 ITGB3 VWF COL1A1

7.94e-05199174M7253
PathwayWP_FOCAL_ADHESION

LAMA5 ITGB3 VWF COL1A1

7.94e-05199174M39402
PathwayREACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING

VWF COL1A1

8.97e-0512172MM15093
PathwayREACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN

VWF COL1A1

8.97e-0512172MM15452
PathwayREACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING

VWF COL1A1

8.97e-0512172M27352
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

ITGB3 VWF COL1A1

9.70e-0576173MM14867
PathwayWP_OSTEOBLAST_SIGNALING

ITGB3 COL1A1

1.24e-0414172M39599
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

ITGB3 VWF COL1A1

1.35e-0485173M16441
PathwayREACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

ITGB3 VWF

1.42e-0415172M12101
PathwayREACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

ITGB3 VWF

1.42e-0415172M1262
PathwayREACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

ITGB3 VWF

1.42e-0415172MM14959
PathwayREACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

ITGB3 VWF

1.42e-0415172MM14961
PathwayREACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN

VWF COL1A1

1.63e-0416172M9450
PathwayREACTOME_DISEASES_OF_HEMOSTASIS

VWF COL1A1

2.31e-0419172M48230
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

LAMA5 ITGB3 VWF COL1A1

3.94e-04302174M39719
PathwayREACTOME_SYNDECAN_INTERACTIONS

ITGB3 COL1A1

4.72e-0427172M27217
PathwayREACTOME_INTEGRIN_SIGNALING

ITGB3 VWF

4.72e-0427172M760
PathwayREACTOME_INTEGRIN_SIGNALING

ITGB3 VWF

5.08e-0428172MM14958
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

LAMA5 ITGB3 VWF COL1A1

5.27e-04326174MM15917
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA5 COL1A1

5.84e-0430172M27772
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMA5 COL1A1

5.84e-0430172MM15812
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMA5 COL1A1

5.84e-0430172M39641
PathwayWP_PI3KAKT_SIGNALING

LAMA5 ITGB3 VWF COL1A1

6.10e-04339174M39736
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

ITGB3 COL1A1

6.65e-0432172MM14924
PathwayREACTOME_MAP2K_AND_MAPK_ACTIVATION

ITGB3 VWF

9.88e-0439172MM15272
PathwayREACTOME_MAP2K_AND_MAPK_ACTIVATION

ITGB3 VWF

1.04e-0340172M27557
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA5 COL1A1

1.09e-0341172M27778
PathwayPID_INTEGRIN3_PATHWAY

ITGB3 COL1A1

1.20e-0343172M53
PathwayREACTOME_SIGNALING_BY_MODERATE_KINASE_ACTIVITY_BRAF_MUTANTS

ITGB3 VWF

1.31e-0345172M27623
PathwayPID_SYNDECAN_1_PATHWAY

LAMA5 COL1A1

1.37e-0346172M198
PathwayREACTOME_ECM_PROTEOGLYCANS

ITGB3 COL1A1

1.43e-0347172MM14925
PathwayPID_IL4_2PATHWAY

ITGB3 COL1A1

2.64e-0364172M28
PathwayREACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS

ITGB3 VWF

2.72e-0365172M38994
PathwayPID_INTEGRIN1_PATHWAY

LAMA5 COL1A1

2.81e-0366172M18
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

LAMA5 ITGB3

3.33e-0372172M39403
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

ITGB3 VWF COL1A1

3.37e-03257173MM15454
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

ITGB3 VWF COL1A1

3.41e-03258173MM14572
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

LAMA5 ITGB3

3.42e-0373172MM15906
PathwayPID_AVB3_INTEGRIN_PATHWAY

ITGB3 COL1A1

3.51e-0374172M160
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

ITGB3 VWF COL1A1

3.52e-03261173M1077
PathwayREACTOME_SIGNALING_BY_MET

LAMA5 COL1A1

3.99e-0379172M27643
PathwayREACTOME_ONCOGENIC_MAPK_SIGNALING

ITGB3 VWF

4.30e-0382172M27626
PathwayWP_COMPLEMENT_SYSTEM

LAMA5 ITGB3

5.84e-0396172M39581
PathwayREACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2

ITGB3 VWF

1.05e-02130172MM15455
PathwayREACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2

ITGB3 VWF

1.08e-02132172M724
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

LAMA5 COL1A1

1.21e-02140172M587
Pubmed

A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.

KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

4.92e-231621815028290
Pubmed

Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.

KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.02e-171121614962103
Pubmed

The DNA sequence of human chromosome 21.

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

1.61e-1425821910830953
Pubmed

Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.

KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-5

3.12e-114021512359730
Pubmed

The VWF/LRP4/αVβ3-axis represents a novel pathway regulating proliferation of human vascular smooth muscle cells.

LRP4 ITGB3 VWF

7.59e-10421333576766
Pubmed

A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.

ITGB3 VWF COL1A1

4.16e-08122138986815
Pubmed

Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.

ITGB3 VWF

3.47e-07221222134168
Pubmed

Beta3 integrin haplotype influences gene regulation and plasma von Willebrand factor activity.

ITGB3 VWF

3.47e-07221218045606
Pubmed

Nitric oxide inhibits von Willebrand factor-mediated platelet adhesion and spreading through regulation of integrin alpha(IIb)beta(3) and myosin light chain.

ITGB3 VWF

1.04e-06321219765213
Pubmed

Solid-phase von Willebrand factor contains a conformationally active RGD motif that mediates endothelial cell adhesion through the alpha v beta 3 receptor.

ITGB3 VWF

1.04e-0632127505120
Pubmed

Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice.

ITGB3 VWF

1.04e-06321217996853
Pubmed

Integrin alphavbeta3 binding to human alpha5-laminins facilitates FGF-2- and VEGF-induced proliferation of human ECV304 carcinoma cells.

LAMA5 ITGB3

1.04e-06321212691260
Pubmed

Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor.

ITGB3 VWF

1.04e-06321230305279
Pubmed

Isolation and characterization of a collagen binding domain in human von Willebrand factor.

VWF COL1A1

1.04e-0632123490481
Pubmed

Fibrin binds to collagen and provides a bridge for αVβ3 integrin-dependent contraction of collagen gels.

ITGB3 COL1A1

1.04e-06321224840544
Pubmed

Factor VIII/von Willebrand factor in subendothelium mediates platelet adhesion.

VWF COL1A1

1.04e-0632123872140
Pubmed

The Commensal Microbiota Enhances ADP-Triggered Integrin αIIbβ3 Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen.

ITGB3 VWF

1.04e-06321232998468
Pubmed

Integrin alpha(v)beta(3) on human endothelial cells binds von Willebrand factor strings under fluid shear stress.

ITGB3 VWF

1.04e-06321218927433
Pubmed

Assessment of community efforts to advance network-based prediction of protein-protein interactions.

KRTAP10-9 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.48e-0663021636949045
Pubmed

Altered thrombus formation in von Willebrand factor-deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa.

ITGB3 VWF

2.08e-06421218487513
Pubmed

Intercellular calcium communication regulates platelet aggregation and thrombus growth.

ITGB3 VWF

2.08e-06421212668663
Pubmed

Isolation of a novel integrin receptor mediating Arg-Gly-Asp-directed cell adhesion to fibronectin and type I collagen from human neuroblastoma cells. Association of a novel beta 1-related subunit with alpha v.

ITGB3 COL1A1

2.08e-0642121693626
Pubmed

Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins.

ITGB3 VWF

2.08e-06421211071623
Pubmed

ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.

ITGB3 VWF

2.08e-06421217003372
Pubmed

Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3.

ITGB3 VWF

2.08e-0642128918453
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMA5 SPOCK2 VWF COL1A1

3.47e-0617521428071719
Pubmed

Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor.

ITGB3 VWF

3.47e-06521219036705
Pubmed

Inflammation induces hemorrhage in thrombocytopenia.

ITGB3 VWF

3.47e-06521218256319
Pubmed

Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo.

ITGB3 VWF

3.47e-06521216824188
Pubmed

Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor.

KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-5

3.55e-0617621427229929
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

LAMA5 ITGB3 COL1A1

3.65e-065021323658023
Pubmed

Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression.

ITGB3 VWF

5.20e-06621219332769
Pubmed

Inhibition of Hb Binding to GP1bα Abrogates Hb-Mediated Thrombus Formation on Immobilized VWF and Collagen under Physiological Shear Stress.

VWF COL1A1

5.20e-06621227105433
Pubmed

Are integrin alpha(2)beta(1), glycoprotein Ib and vWf levels correlated with their contributions to platelet adhesion on collagen under high-shear flow?

VWF COL1A1

5.20e-06621220063990
Pubmed

von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.

VWF COL1A1

7.28e-0672121939645
Pubmed

Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents.

VWF COL1A1

9.70e-06821220551517
Pubmed

The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.

ITGB3 VWF

1.56e-051021212082590
Pubmed

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.

LAMA5 COL1A1

2.70e-051321236350252
Pubmed

Membrane-type MMPs are indispensable for placental labyrinth formation and development.

LAMA5 COL1A1

3.15e-051421220858856
Pubmed

Integrins and Src: dynamic duo of adhesion signaling.

ITGB3 VWF

3.15e-051421216005629
Pubmed

Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment.

LAMA5 VWF

3.15e-051421236347239
Pubmed

p130Cas: a versatile scaffold in signaling networks.

ITGB3 VWF

3.15e-051421216581250
Pubmed

Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.

VWF COL1A1

3.63e-051521228684544
Pubmed

Ontogeny of stromal organizer cells during lymph node development.

LAMA5 COL1A1

4.15e-051621220237296
Pubmed

Cell-matrix signals specify bone endothelial cells during developmental osteogenesis.

LAMA5 COL1A1

4.15e-051621228218908
Pubmed

Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.

LAMA5 COL1A1

4.15e-051621221067603
Pubmed

Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.

LAMA5 VWF

4.15e-051621226953188
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA5 COL1A1

5.28e-051821211311202
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

LAMA5 COL1A1

5.28e-051821239040056
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

LAMA5 VWF COL1A1

7.23e-0513521328675934
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

LAMA5 VWF COL1A1

9.12e-0514621327068509
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

LAMA5 VWF COL1A1

1.05e-0415321325037231
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA5 COL1A1

1.12e-042621234189436
Pubmed

Osteopotentia regulates osteoblast maturation, bone formation, and skeletal integrity in mice.

ITGB3 COL1A1

1.21e-042721220440000
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMA5 VWF COL1A1

1.36e-0416721322159717
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

ITGB3 COL1A1

1.50e-043021232882513
Pubmed

Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing.

LAMA5 COL1A1

1.60e-043121230305289
Pubmed

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

ITGB3 VWF COL1A1

1.86e-0418621320452482
Pubmed

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

ITGB3 VWF COL1A1

1.86e-0418621320673868
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

LAMA5 COL1A1

2.28e-043721234323105
Pubmed

Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis.

LAMA5 COL1A1

2.41e-043821225572963
Pubmed

Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia.

VWF COL1A1

2.54e-043921230566624
Pubmed

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

ITGB3 VWF

3.85e-044821228924218
InteractionMOBP interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.86e-1123205int:MOBP
InteractionHOXA1 interactions

LAMA5 KRTAP10-9 NELL2 KRTAP10-11 KRTAP10-4 KRTAP10-7 VWF KRTAP10-5 TCF19

2.14e-11356209int:HOXA1
InteractionSPATA3 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

2.35e-1124205int:SPATA3
InteractionLCE3B interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

7.48e-1046205int:LCE3B
InteractionZSCAN26 interactions

LRP4 KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-5

2.71e-0959205int:ZSCAN26
InteractionLCE3E interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

2.96e-0960205int:LCE3E
InteractionKRTAP5-2 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

3.50e-0962205int:KRTAP5-2
InteractionLCE3C interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

5.20e-0967205int:LCE3C
InteractionLCE1E interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

5.61e-0968205int:LCE1E
InteractionLCE2A interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

6.05e-0969205int:LCE2A
InteractionLCE1D interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

6.51e-0970205int:LCE1D
InteractionRSPO2 interactions

KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-6

7.40e-0924204int:RSPO2
InteractionLCE3D interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

8.06e-0973205int:LCE3D
InteractionLCE2D interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

8.64e-0974205int:LCE2D
InteractionWT1 interactions

KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-5

9.90e-0976205int:WT1
InteractionLCE4A interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.28e-0880205int:LCE4A
InteractionKRTAP4-4 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.37e-0881205int:KRTAP4-4
InteractionLCE2B interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.37e-0881205int:LCE2B
InteractionLCE1A interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.65e-0884205int:LCE1A
InteractionLCE1B interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.75e-0885205int:LCE1B
InteractionLCE5A interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

2.33e-0890205int:LCE5A
InteractionKRTAP4-11 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

2.61e-0892205int:KRTAP4-11
InteractionLCE1F interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

2.61e-0892205int:LCE1F
InteractionKRTAP5-6 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

2.91e-0894205int:KRTAP5-6
InteractionKRTAP9-8 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

3.97e-08100205int:KRTAP9-8
InteractionZNF440 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

6.30e-0840204int:ZNF440
InteractionZNF264 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

6.97e-0841204int:ZNF264
InteractionZNF433 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

9.99e-0810203int:ZNF433
InteractionCATSPER1 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-5

1.27e-07126205int:CATSPER1
InteractionZNF155 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6

1.37e-0711203int:ZNF155
InteractionKRTAP4-2 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.60e-07132205int:KRTAP4-2
InteractionGLIDR interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

1.83e-0712203int:GLIDR
InteractionZNF792 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

3.32e-0760204int:ZNF792
InteractionKRTAP10-1 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

3.34e-07153205int:KRTAP10-1
InteractionOTX1 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-5

3.56e-07155205int:OTX1
InteractionZNF625 interactions

KRTAP10-9 KRTAP10-4 KRTAP10-7

3.77e-0715203int:ZNF625
InteractionKRTAP5-4 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

4.05e-0763204int:KRTAP5-4
InteractionKRTAP10-5 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

4.17e-07160205int:KRTAP10-5
InteractionKRTAP10-11 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

4.31e-0764204int:KRTAP10-11
InteractionNPDC1 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

4.59e-0765204int:NPDC1
InteractionZNF32 interactions

KRTAP10-4 KRTAP10-7 KRTAP10-5

4.64e-0716203int:ZNF32
InteractionKRTAP5-11 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

4.89e-0766204int:KRTAP5-11
InteractionCRCT1 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

4.89e-0766204int:CRCT1
InteractionKRTAP5-3 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

4.89e-0766204int:KRTAP5-3
InteractionZNF696 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

5.51e-0768204int:ZNF696
InteractionZNF578 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

5.63e-0717203int:ZNF578
InteractionKRTAP4-5 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

8.64e-0776204int:KRTAP4-5
InteractionLCE3A interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

8.64e-0776204int:LCE3A
InteractionSMCP interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

1.01e-0679204int:SMCP
InteractionNKD1 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6

1.10e-0621203int:NKD1
InteractionKRTAP5-9 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.35e-06203205int:KRTAP5-9
InteractionSPACA9 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

1.46e-0623203int:SPACA9
InteractionLCE2C interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.56e-0688204int:LCE2C
InteractionSLC23A1 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

2.14e-0626203int:SLC23A1
InteractionNUFIP2 interactions

KRTAP10-9 NELL2 KRTAP10-11 KRTAP10-7 VWF KRTAP10-5

2.29e-06417206int:NUFIP2
InteractionZNF439 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

2.41e-0627203int:ZNF439
InteractionFAM74A4 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

2.41e-0627203int:FAM74A4
InteractionFAM76B interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

2.50e-0699204int:FAM76B
InteractionPRKAB2 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5 TCF19

2.72e-06234205int:PRKAB2
InteractionTNP2 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

3.69e-0631203int:TNP2
InteractionSPRY1 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

3.95e-06111204int:SPRY1
InteractionBCL6B interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

4.47e-0633203int:BCL6B
InteractionZNF697 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

4.47e-0633203int:ZNF697
InteractionSLC6A20 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

4.90e-0634203int:SLC6A20
InteractionMT1DP interactions

KRTAP10-9 KRTAP10-5

5.61e-064202int:MT1DP
InteractionZSCAN21 interactions

LRP4 KRTAP10-9 KRTAP10-7 KRTAP10-5

6.95e-06128204int:ZSCAN21
InteractionZNF587 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

8.59e-06135204int:ZNF587
InteractionKRTAP9-3 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

9.91e-06140204int:KRTAP9-3
InteractionZNF20 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

1.08e-0544203int:ZNF20
InteractionCLK4 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6

1.08e-0544203int:CLK4
InteractionKRTAP9-2 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

1.27e-05149204int:KRTAP9-2
InteractionKIAA0040 interactions

KRTAP10-9 KRTAP10-6

1.40e-056202int:KIAA0040
InteractionAVPI1 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6

1.41e-0548203int:AVPI1
InteractionZNF490 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6

1.59e-0550203int:ZNF490
InteractionZBTB24 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

1.64e-05159204int:ZBTB24
InteractionKRTAP4-12 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

1.72e-05161204int:KRTAP4-12
InteractionCREB5 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

1.85e-05164204int:CREB5
InteractionHHEX interactions

KRTAP10-7 KRTAP10-6 KRTAP10-5

2.01e-0554203int:HHEX
InteractionMXI1 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

2.12e-0555203int:MXI1
InteractionZFP41 interactions

LRP4 NELL2 KRTAP10-7

2.36e-0557203int:ZFP41
InteractionZNF679 interactions

KRTAP10-6 KRTAP10-5

2.61e-058202int:ZNF679
InteractionZNF124 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

2.62e-0559203int:ZNF124
InteractionZNF572 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

2.90e-0561203int:ZNF572
InteractionKRTAP12-1 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

3.20e-0563203int:KRTAP12-1
InteractionCCDC26 interactions

KRTAP10-9 KRTAP10-7

4.19e-0510202int:CCDC26
InteractionNAXD interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6

4.58e-0571203int:NAXD
InteractionZNF778 interactions

LRP4 KRTAP10-7

5.12e-0511202int:ZNF778
InteractionPOM121L8P interactions

KRTAP10-7 KRTAP10-5

5.12e-0511202int:POM121L8P
InteractionLCE1C interactions

KRTAP10-9 KRTAP10-11 KRTAP10-5

5.83e-0577203int:LCE1C
InteractionCOL1A2 interactions

ITGB3 VWF COL1A1

6.06e-0578203int:COL1A2
InteractionZNF563 interactions

LRP4 KRTAP10-6

6.14e-0512202int:ZNF563
InteractionZNF774 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6

6.30e-0579203int:ZNF774
InteractionZNF707 interactions

LRP4 KRTAP10-7 KRTAP10-5

6.30e-0579203int:ZNF707
InteractionBMP7 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

6.54e-0580203int:BMP7
InteractionWT1-AS interactions

KRTAP10-9 KRTAP10-5

7.25e-0513202int:WT1-AS
InteractionPOU4F2 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-5

7.30e-0583203int:POU4F2
InteractionKRTAP10-9 interactions

KRTAP10-9 KRTAP10-11 KRTAP10-7 KRTAP10-5

8.31e-05241204int:KRTAP10-9
InteractionZNF844 interactions

KRTAP10-9 KRTAP10-7

8.45e-0514202int:ZNF844
InteractionHPCAL1 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-5

8.69e-0588203int:HPCAL1
InteractionDHX57 interactions

KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-5

9.88e-05252204int:DHX57
Cytoband21q22.3

KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

5.77e-1612821821q22.3
CytobandEnsembl 112 genes in cytogenetic band chr21q22

KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

3.56e-12377218chr21q22
CytobandEnsembl 112 genes in cytogenetic band chr17q21

KRTAP16-1 ITGB3 COL1A1

1.26e-03473213chr17q21
GeneFamilyKeratin associated proteins

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

3.49e-16109189619
CoexpressionNABA_CORE_MATRISOME

KCP LAMA5 SPOCK2 NELL2 CILP2 VWF OTOG COL1A1

7.83e-12270198MM17057
CoexpressionNABA_CORE_MATRISOME

KCP LAMA5 SPOCK2 NELL2 CILP2 VWF OTOG COL1A1

9.07e-12275198M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP LAMA5 NELL2 CILP2 VWF OTOG

3.47e-09191196MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP LAMA5 NELL2 CILP2 VWF OTOG

4.05e-09196196M3008
CoexpressionNABA_MATRISOME

KCP LAMA5 SPOCK2 NELL2 CILP2 VWF OTOG COL1A1

2.41e-071008198MM17056
CoexpressionNABA_MATRISOME

KCP LAMA5 SPOCK2 NELL2 CILP2 VWF OTOG COL1A1

2.76e-071026198M5889
CoexpressionDORSEY_GAB2_TARGETS

ITGB3 COL1A1

2.14e-0430192M14557
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K27ME3

KRTAP10-11 KRTAP10-7

2.14e-0430192MM835
CoexpressionDELYS_THYROID_CANCER_UP

LRP4 SPOCK2 NELL2 COL1A1

2.60e-04445194M3645
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500

KCP SPOCK2 NELL2 VWF COL1A1

7.01e-06489135Facebase_RNAseq_e8.5_Paraxial Mesoderm_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

KCP LAMA5 SPOCK2 NELL2 VWF COL1A1

1.19e-05973136Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

KCP LAMA5 SPOCK2 NELL2 VWF COL1A1

1.21e-05976136Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

KCP LAMA5 SPOCK2 NELL2 VWF COL1A1

1.26e-05984136Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000

KCP SPOCK2 NELL2 VWF COL1A1

1.84e-04967135Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000

KCP SPOCK2 NELL2 VWF COL1A1

1.84e-04967135Facebase_RNAseq_e9.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000

KCP SPOCK2 NELL2 VWF COL1A1

1.84e-04967135Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000

KCP SPOCK2 NELL2 VWF COL1A1

1.85e-04968135Facebase_RNAseq_e9.5_Facial Mesenchyne_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

KCP SPOCK2 NELL2 VWF COL1A1

1.88e-04972135Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000

KCP LAMA5 SPOCK2 NELL2 COL1A1

1.90e-04974135Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000

KCP SPOCK2 NELL2 VWF COL1A1

1.94e-04978135Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#5

KCP VWF COL1A1

3.94e-04244133Facebase_RNAseq_e9.5_Olfactory Placode_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#3

KCP VWF COL1A1

4.18e-04249133Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5

KCP VWF COL1A1

5.64e-04276133Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4

KCP VWF COL1A1

7.05e-04298133Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5

KCP AKAP13 VWF COL1A1

7.89e-04734134Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#3_top-relative-expression-ranked_500

ITGB3 COL1A1

8.87e-0473132DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k3_500
CoexpressionAtlasratio_StemCell-blastocyst_vs_cbCD34_top-relative-expression-ranked_500_k-means-cluster#2

AKAP13 VWF

8.87e-0473132ratio_SC-blastocyst_vs_cbCD34_500_K2
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

KRTAP16-1 KRTAP10-9 KRTAP10-2 KRTAP10-11 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-5

8.83e-18146219522c32103c24fc26836bb5b642083904682d9292
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma,_Immature_Teratoma,_Mature_Teratoma,_Yolk_Sac_Tumor-1|TCGA-Testes / Sample_Type by Project: Shred V9

KRTAP10-2 KRTAP10-11 KRTAP10-6

1.11e-05932132a44d58ae88c05acb18adc959bc2f7cdcc1ac0b3
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-2|TCGA-Endometrium / Sample_Type by Project: Shred V9

KRTAP10-11 KRTAP10-7 KRTAP10-6

1.59e-05105213744be8b4255bef3a973db7e4306e52387852e502
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 ITGB3 COL1A1

3.76e-05140213e442c46979d725ec82f525a001c46d971fcade4d
ToppCellE17.5-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP4 LAMA5 SPOCK2

4.62e-05150213201d5b68e71c6c003285428be96c488e6d526edf
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB3 VWF OTOG

5.19e-051562131c2920f4356789a9c11d5ea1eaafb18a50b19ed7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB3 VWF OTOG

5.19e-051562130695ac0f02d059ecf813d61d3c9d4c76d1d85834
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB3 VWF OTOG

5.19e-05156213a45fbe02cd03bd4a097f21368bc1179779ba0db8
ToppCellInfluenza_Severe-CD4+_Tcm|World / Disease group and Cell class

SPOCK2 NELL2 COL1A1

5.29e-05157213842ac087d3d51dba3a6b6937733b73a81aa15e1b
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Cajal-Retzius|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

SPOCK2 KRTAP10-2 KRTAP10-11

5.92e-05163213c1484e4de8b10e2f5fb14a7c02b2a015ffe0305e
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ITGB3 SPOCK2 TCF19

6.25e-05166213f4698fd08965936d51695d571bd10fb77330d916
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|356C / Donor, Lineage, Cell class and subclass (all cells)

AKAP13 SPOCK2 CILP2

6.47e-051682139d6ca10c272aea28082c09d469940f7232f6461c
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP LRP4 COL1A1

6.70e-05170213d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellInfluenza_Severe-CD4+_Tcm|Influenza_Severe / Disease group and Cell class

SPOCK2 NELL2 COL1A1

6.94e-0517221347865a04968ca28c6ff125159d9a23e37c8b8af1
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

AKAP13 SPOCK2 CILP2

7.18e-0517421399d7421ad5eafe7751ef90698a92f683aa33bca8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP SPOCK2 VWF

7.94e-051802139c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP SPOCK2 VWF

7.94e-05180213499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP SPOCK2 VWF

7.94e-051802132405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGB3 NELL2 COL1A1

8.61e-05185213d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellsevere_influenza-CD4+_Tcm|severe_influenza / disease group, cell group and cell class (v2)

SPOCK2 NELL2 COL1A1

9.03e-05188213633e5545f49b1b864b0ffa5fc9688d270690f884
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB3 COL1A1 TCF19

9.91e-0519421304ecb609d233a4b12e275c604810937830363e17
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB3 COL1A1 TCF19

9.91e-05194213775600880bb77781de48085d8744c1030223de1f
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

AKAP13 SPOCK2 NELL2

1.01e-041952136687e579582d7a239bee80846de0cf827a6f6a62
ToppCell-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SPOCK2 CILP2 COL1A1

1.01e-04195213e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

NELL2 CILP2 COL1A1

1.05e-04198213196257c4420ac801ed9fbb444f11718adb7560ae
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_Tcm|Influenza_Severe / Disease, condition lineage and cell class

SPOCK2 NELL2 COL1A1

1.05e-04198213fc99f2e300d76126d05c0c43e11cdbbeb74f6f0d
ToppCell(4)_Endothelial_cells-(4)_Blood_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

LAMA5 AKAP13 VWF

1.07e-04199213e24d70e79f25cdd3300bf5e2322713355264d4c5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP4 LAMA5 COL1A1

1.07e-04199213edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_Tem|Int-URO / Disease, condition lineage and cell class

SPOCK2 NELL2 TCF19

1.07e-04199213c55634d4b66ab4e3f9262a83d993ea0c5f01ea61
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_Tcm|Leuk-UTI / Disease, condition lineage and cell class

SPOCK2 NELL2 VWF

1.07e-041992136a1d84f61e1efaab541910926d6911122372659f
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocye.Tnr.Cspg5_(Cspg5)|Striatum / BrainAtlas - Mouse McCarroll V32

CILP2 OTOG

4.92e-0470212c6d3f8cd3f79e2beb826b07a6b9f3ab35d4f23ea
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocye.Tnr.Cspg5_(Cspg5)-|Striatum / BrainAtlas - Mouse McCarroll V32

CILP2 OTOG

4.92e-0470212823921f8bf585d45f24f627b2b77b228898eb85a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3-Tnr|Striatum / BrainAtlas - Mouse McCarroll V32

CILP2 OTOG

4.92e-0470212d2be16550c572ba77261c978648e61dba3eab6bd
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3|Striatum / BrainAtlas - Mouse McCarroll V32

CILP2 OTOG

4.92e-047021252bde49a05f2387fe3e4357422e155bee2e86ae6
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCP VWF

5.49e-04742120288a3f4eafbc359d01cde4ba58f946dd07c77cb
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCP VWF

5.49e-047421257884ade66fe39398351685189df5efd7aea0aab
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCP VWF

5.49e-047421213093139a75bfe11f6b032c9fb402efcc703551c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCP VWF

5.49e-04742127f7de9e8142d2435391ee965cee5628e412f0705
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2-Inhibitory_Neuron.Gad1Gad2.Otx2-Chrna3_(SN/VTA_(dorsal_SNr))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CILP2 TCF19

5.64e-0475212730a08f846a155d2c892259f2c610081d40fc2c8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CILP2 TCF19

5.64e-0475212f0185de0ce497997df1027a51c099d91294bba07
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2-Inhibitory_Neuron.Gad1Gad2.Otx2-Chrna3_(SN/VTA_(dorsal_SNr))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CILP2 TCF19

5.64e-047521259fe56388697037b335f334cb3461f15c7b3b506
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP VWF

6.90e-04832123aa95bf2d8ac37e648037faf3d54ebb243a4fde1
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP VWF

6.90e-048321270804dd63221dd5ed26068ec1b50f11875abbc50
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP VWF

6.90e-0483212c1818411438f53aec76afead5c8caab701b95d39
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP VWF

6.90e-04832121e7af8aaa20b4c2a77cf2f330113db0faa9d483c
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

7.58e-0487212cc89f4176b70d4eb5b5bf0ff2319b5f1f9e292c0
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

7.58e-04872124274e04fa4aca85c2cefd8c5e03d0fa4a4f15536
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

7.58e-048721254cbdf80aae3595eaace20c7cbac763282558213
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

7.58e-04872128b1a0bd5d6af32afaca19e9c69f86530bbaa309d
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

8.47e-0492212ed282f0f3da1593bdec5a2b20af5b8f058574167
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

8.47e-0492212c5f30d58f235f7a72dfe63f58999c4680502576f
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

8.47e-049221227072dbf6819dca41e41267dc250abfaaf175b2f
ToppCellTCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue-1|TCGA-Prostate / Sample_Type by Project: Shred V9

ITGB3 KRTAP10-5

1.10e-031052122ea7cd2b5f0728e255aebd573028b0a1dc4410d2
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPOCK2 OTOG

1.16e-03108212d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OTOG TCF19

1.21e-03110212c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-hematologic-erythrocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP4 OTOG

1.58e-03126212cd02f3d4a3fadd24f3a298639b392f0354d227d2
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP2 COL1A1

1.58e-03126212c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-hematologic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP4 OTOG

1.58e-03126212f2ec5aa6c649ae1ff99519f6897cf207dc292edf
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tfh|GI_small-bowel / Manually curated celltypes from each tissue

SPOCK2 NELL2

1.58e-03126212d0d3e25e4fb074a76313fc90d8c3828b1d8ea486
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP4 OTOG

1.58e-0312621261a7e400cbc81691b21cd3c37376c1d19fec2270
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KCP VWF

1.70e-03131212d5bc40cd585582856881081b7130dec3515b4ae0
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCP TCF19

1.91e-031392122fb51abb3ce88c21726c026d6365b2582e2e79f6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCP NELL2

2.00e-03142212199a0a1024b6cc446f5ca1f277846a2bdb227a9f
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|356C / Donor, Lineage, Cell class and subclass (all cells)

SPOCK2 NELL2

2.02e-03143212e8fc6540a48086f58bc3f42dabe392ef46715b9e
ToppCellTCGA-Brain-Recurrent_Tumor|TCGA-Brain / Sample_Type by Project: Shred V9

CILP2 COL1A1

2.02e-03143212eeb8ce6e051e18b82b74aaf2fc23f0cb87fc96d5
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|390C / Donor, Lineage, Cell class and subclass (all cells)

KCP NELL2

2.02e-03143212d877d914e4e74db2053baa310d318d6440e672bc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CILP2 TCF19

2.14e-03147212c8e5bdc3538089acd35a4b41390afaec0ac6d1aa
ToppCellICU-SEP-Lymphocyte-T_NK-CD8_Naive|ICU-SEP / Disease, Lineage and Cell Type

SPOCK2 NELL2

2.20e-03149212a66f3ebf6214b269b137ddd5f4d8d7fb3ef2d962
ToppCellCOVID-19_Severe-CD8+_T_naive|COVID-19_Severe / disease group, cell group and cell class

SPOCK2 NELL2

2.28e-03152212e6dbf20504c4fb73d1084b587e040855335b8959
ToppCellInt-URO-Lymphocyte-T_NK-CD8_Naive|Int-URO / Disease, Lineage and Cell Type

SPOCK2 NELL2

2.28e-0315221252d6f9cf1f4637c922f582705d625b4cbe3dc0c2
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CILP2 COL1A1

2.31e-03153212151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 NELL2

2.34e-0315421289c9c9918af32f3952790b41f1471b2c80ffce2f
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

KCP LRP4

2.34e-03154212afdc385397c7b13c9348eeef95f109f2363057ae
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

KCP COL1A1

2.37e-03155212b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 NELL2

2.40e-031562127569cab30caafcb273e8ef0b73c9e1bf87076984
ToppCellsevere_COVID-19-CD8+_T_naive|severe_COVID-19 / disease group, cell group and cell class (v2)

SPOCK2 NELL2

2.40e-0315621247aa46cdf5af9834f4b890ac6ce5e8d548ee98db
ToppCellBac-SEP-Lymphocyte-T_NK-CD4_TEM|Bac-SEP / Disease, Lineage and Cell Type

SPOCK2 NELL2

2.40e-03156212ef6bad99bcb30956863cd490c613e251f3b27ba0
ToppCellmetastatic_Brain-T/NK_cells-Naive_CD8+_T|metastatic_Brain / Location, Cell class and cell subclass

SPOCK2 NELL2

2.40e-031562121dcb0b2d1c4b524e692d40e8403dbf7140af19b4
ToppCellInfluenza_Severe-CD4+_T_naive|Influenza_Severe / Disease group and Cell class

SPOCK2 NELL2

2.43e-03157212287bdc4e455cd0160261a93d13538e0def49fcd4
ToppCellsevere_influenza-CD4+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

SPOCK2 NELL2

2.46e-03158212ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGB3 TCF19

2.49e-03159212f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 TCF19

2.49e-031592122233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCellsevere_influenza-CD8+_T_naive|World / disease group, cell group and cell class (v2)

NELL2 CILP2

2.52e-03160212a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA5 SPOCK2

2.52e-0316021258ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

KRTAP16-1 VWF

2.52e-031602120d4880f85565d8c540c94a8f8109147b3029279a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-2_VIP_PPAPDC1A|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CILP2 TCF19

2.52e-031602127619c31815e41a42864b34ca825c96a2487a5da9
ToppCellURO-Lymphocyte-T_NK-CD4_TEM|URO / Disease, Lineage and Cell Type

SPOCK2 NELL2

2.52e-03160212e406f77b1c1a01d74f39ba65f99d5f8c7d75faf1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF OTOG

2.52e-0316021233050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF TCF19

2.56e-03161212f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 OTOG

2.56e-03161212b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 OTOG

2.56e-03161212f7a89c481f789f624102857be722c95fbeb47595
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

KRTAP16-1 SPOCK2

2.56e-03161212b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCellCOVID-CD8-CD8_2|COVID / Condition, Cell_class and T cell subcluster

SPOCK2 NELL2

2.56e-03161212307dcc17475413cd9eb70c27bc447f938ee5723d
ToppCellHealthy/Control-Treg|World / Disease group and Cell class

SPOCK2 CILP2

2.56e-03161212457297cda5c9cee3bcc069fdecbbe24def027e5f
ToppCellsevere_influenza-CD8+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

NELL2 CILP2

2.56e-0316121282196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCP NELL2

2.56e-031612125fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL1A1 TCF19

2.59e-031622123f264263878af630921911c2b344ac56eb1e7099
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SPOCK2 NELL2

2.59e-03162212b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellsevere_influenza-CD4+_Tcm|World / disease group, cell group and cell class (v2)

SPOCK2 NELL2

2.59e-031622127137990e6e1473665911e39a22092a05ae25ce74
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SPOCK2 COL1A1

2.59e-0316221257d627259d27f39885bf416d74bcb6656db6e27b
ComputationalAdhesion molecules.

LAMA5 VWF COL1A1

1.18e-0414183MODULE_122
ComputationalBlood coagulation factors.

ITGB3 VWF

2.53e-043382MODULE_131
ComputationalBone remodeling.

SPOCK2 COL1A1

6.80e-045482MODULE_234
DrugGRGDTP

ITGB3 VWF COL1A1

3.24e-088203CID004644096
DrugGrgds

LAMA5 ITGB3 VWF COL1A1

7.61e-0783204CID000123811
DrugGrgdspk

ITGB3 VWF COL1A1

7.63e-0721203CID000130667
DrugRgds Peptide

LAMA5 ITGB3 VWF COL1A1

2.03e-06106204CID000107775
DrugGdrgdsp

LAMA5 ITGB3 VWF COL1A1

2.27e-06109204CID000115346
DrugGrgesp

ITGB3 VWF COL1A1

6.51e-0642203CID000492974
DrugXamoterol hemifumarate [73210-73-8]; Up 200; 5uM; MCF7; HT_HG-U133A

LRP4 ITGB3 NELL2 COL1A1

2.27e-051952043401_UP
DrugCefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A

ITGB3 SPOCK2 NELL2 COL1A1

2.46e-051992042235_UP
DrugRgd Peptide

LAMA5 ITGB3 VWF COL1A1

5.03e-05239204CID000104802
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMA5 ITGB3 COL1A1

5.09e-0583203CID011968896
DrugRgdf peptide

ITGB3 VWF

6.63e-0514202CID003080994
Druglotrafiban

ITGB3 VWF

6.63e-0514202CID000080274
Drugticlopidine

ITGB3 VWF COL1A1

9.69e-05103203CID000005472
DrugPPACK

ITGB3 VWF COL1A1

1.28e-04113203CID003036757
DrugALT-711

LAMA5 COL1A1

1.52e-0421202CID000216304
DrugMOMC

VWF COL1A1

1.68e-0422202CID000128338
Diseaseureidopropionic acid measurement

SPOCK2 OTOG

2.14e-0516132EFO_0010542
Diseasevenous thromboembolism, tissue plasminogen activator measurement

LRP4 VWF

4.51e-0523132EFO_0004286, EFO_0004791
DiseaseNephrotic Syndrome

LAMA5 COL1A1

6.25e-0527132C0027726
Diseasefactor XI measurement, venous thromboembolism

LRP4 VWF

7.74e-0530132EFO_0004286, EFO_0004694
Diseasefactor VIII measurement, venous thromboembolism

LRP4 VWF

9.97e-0534132EFO_0004286, EFO_0004630
Diseaseend stage renal disease (is_implicated_in)

ITGB3 VWF

1.46e-0441132DOID:783 (is_implicated_in)
Diseaseend stage renal disease (is_marker_for)

VWF COL1A1

1.83e-0446132DOID:783 (is_marker_for)
Diseasepulmonary fibrosis (biomarker_via_orthology)

VWF COL1A1

2.17e-0450132DOID:3770 (biomarker_via_orthology)
Diseasesystemic scleroderma (is_marker_for)

VWF COL1A1

2.44e-0453132DOID:418 (is_marker_for)
Diseasediabetic retinopathy (is_marker_for)

ITGB3 VWF

2.53e-0454132DOID:8947 (is_marker_for)
Diseasevenous thromboembolism, fibrinogen measurement

LRP4 VWF

3.90e-0467132EFO_0004286, EFO_0004623

Protein segments in the cluster

PeptideGeneStartEntry
CCPGSPVAQTESPCD

AKAP13

341

Q12802
LPENECCPRCVTDPC

NELL2

746

Q99435
SSRDDPSAPCVSCPC

LAMA5

1901

O15230
TRCDCTPCGTEACDP

LAMA5

2021

O15230
GDTCEKCPTCPDACT

ITGB3

621

P05106
DCPESCCELPCGTPS

KRTAP10-2

21

P60368
DCPESCCEPPCCAPS

KRTAP10-4

31

P60372
CVSSPCCQAVCEPSP

KRTAP10-4

181

P60372
DCPESCCEPPCGTAP

KRTAP10-5

21

P60370
CVSSPCCQAACEPSP

KRTAP10-5

46

P60370
CKPVCCVPTCSEDSS

KRTAP10-5

136

P60370
DCPESCCEPPCCAPA

KRTAP10-6

36

P60371
CVSSPCCQAVCEPSP

KRTAP10-6

181

P60371
PVCCVPTCSEDSSSC

KRTAP10-6

236

P60371
DCPESCCEPPCCAPA

KRTAP10-7

36

P60409
CVSSPCCQAVCEPSP

KRTAP10-7

181

P60409
PVCCVPTCSDDSGSC

KRTAP10-7

236

P60409
DCPESCCEPPCCATS

KRTAP10-9

21

P60411
DCPESCCEPPCSAPS

KRTAP10-11

21

P60412
DCPESCCEPPCCAPA

KRTAP10-12

31

P60413
PSCPVSSCAQPLCCD

KRTAP16-1

61

A8MUX0
PLCCDPVICEPSCSV

KRTAP16-1

71

A8MUX0
PVCCEATTCEPSCSV

KRTAP16-1

91

A8MUX0
PVCCEPAICEPSCSV

KRTAP16-1

151

A8MUX0
AVCCDPSPCEPSCSE

KRTAP16-1

246

A8MUX0
CACGDCPDSIPECQE

OTOG

2576

Q6ZRI0
LNCLESCTPPGECCP

KCP

176

Q6ZWJ8
CPGCSLDTCECPDHI

CILP2

196

Q8IUL8
CCPVCPDGSESPTDQ

COL1A1

91

P02452
PCAAPCCCLPQEETV

TCF19

291

Q9Y242
IPGTCCDTCEEPECN

VWF

2711

P04275
CEGPCPCPTEQAATS

SPOCK2

176

Q92563
VCACPDEPDSRPCSL

LRP4

1636

O75096