Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpoly(A) binding

RBMS3 PAN3 LARP4

7.25e-0529563GO:0008143
GeneOntologyMolecularFunctionpoly-purine tract binding

RBMS3 PAN3 LARP4

1.52e-0437563GO:0070717
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PTPN6 ENPP1 RPP40 IARS1 DDHD1 ACP3 ZC3H12C H6PD PAN3

3.78e-04807569GO:0016788
MousePhenoeffusion

FOXN1 HEG1 PIK3CA ENPP1 ANKRD17 ECE1

1.42e-05152496MP:0021205
MousePhenoabnormal thymus development

FOXN1 PTPN6 ECE1

2.66e-0517493MP:0000704
MousePhenoabnormal enzyme/coenzyme activity

ENAM POMGNT2 ENPP1 GZMH GZMB H6PD DSEL

5.87e-05287497MP:0005584
MousePhenoascites

FOXN1 HEG1 PIK3CA

7.78e-0524493MP:0005324
DomainATPase_dyneun-rel_AAA

MDN1 DNAH6 DNAH1

9.58e-0614573IPR011704
DomainAAA_5

MDN1 DNAH6 DNAH1

9.58e-0614573PF07728
DomainPI3Ka

PIK3CA PI4KA

3.25e-049572PF00613
Domain-

PIK3CA PI4KA

3.25e-0495721.25.40.70
DomainPI3Ka

PIK3CA PI4KA

3.25e-049572SM00145
DomainPIK_HELICAL

PIK3CA PI4KA

4.05e-0410572PS51545
DomainPI_Kinase

PIK3CA PI4KA

4.05e-0410572IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3CA PI4KA

4.05e-0410572IPR001263
DomainCarboxyPept_regulatory_dom

EMC7 CPD

6.99e-0413572IPR014766
Domain-

EMC7 CPD

6.99e-04135722.60.40.1120
DomainDynein_heavy_chain_D4_dom

DNAH6 DNAH1

8.13e-0414572IPR024317
DomainDynein_HC_stalk

DNAH6 DNAH1

8.13e-0414572IPR024743
DomainDynein_heavy_dom-2

DNAH6 DNAH1

8.13e-0414572IPR013602
DomainDHC_N2

DNAH6 DNAH1

8.13e-0414572PF08393
DomainMT

DNAH6 DNAH1

8.13e-0414572PF12777
DomainAAA_8

DNAH6 DNAH1

8.13e-0414572PF12780
DomainDHC_fam

DNAH6 DNAH1

9.37e-0415572IPR026983
DomainDynein_heavy_dom

DNAH6 DNAH1

9.37e-0415572IPR004273
DomainDynein_heavy

DNAH6 DNAH1

9.37e-0415572PF03028
DomainPI3/4_kinase_CS

PIK3CA PI4KA

9.37e-0415572IPR018936
Domain-

PIK3CA PI4KA

1.07e-03165721.10.1070.11
DomainPI3Kc

PIK3CA PI4KA

1.07e-0316572SM00146
DomainCarboxyPept-like_regulatory

EMC7 CPD

1.21e-0317572IPR008969
DomainPI3/4_kinase_cat_dom

PIK3CA PI4KA

1.36e-0318572IPR000403
DomainPI3_PI4_kinase

PIK3CA PI4KA

1.36e-0318572PF00454
DomainPI3_4_KINASE_3

PIK3CA PI4KA

1.36e-0318572PS50290
DomainPI3_4_KINASE_1

PIK3CA PI4KA

1.36e-0318572PS00915
DomainPI3_4_KINASE_2

PIK3CA PI4KA

1.36e-0318572PS00916
DomainRRM

RBMS3 LARP4 HNRNPL CPSF7

4.33e-03217574SM00360
Domain-

FOXN1 FOXL2 IRF4 LARP4

4.40e-032185741.10.10.10
DomainRRM_dom

RBMS3 LARP4 HNRNPL CPSF7

5.07e-03227574IPR000504
DomainRRM

RBMS3 LARP4 HNRNPL CPSF7

5.31e-03230574PS50102
DomainWHTH_DNA-bd_dom

FOXN1 FOXL2 IRF4 LARP4

6.35e-03242574IPR011991
Domain-

RBMS3 LARP4 HNRNPL CPSF7

6.53e-032445743.30.70.330
DomainPTB

EPS8 SHC3

6.63e-0340572SM00462
DomainPTB/PI_dom

EPS8 SHC3

6.95e-0341572IPR006020
DomainNucleotide-bd_a/b_plait

RBMS3 LARP4 HNRNPL CPSF7

7.92e-03258574IPR012677
DomainTF_fork_head_CS_2

FOXN1 FOXL2

8.69e-0346572IPR030456
Pubmed

Defining the membrane proteome of NK cells.

MDN1 IARS1 PI4KA GZMH GZMB ANKRD17 IRF4 CPD NOL9 ECE1 LARP4 F5 HNRNPL CPSF7

5.49e-091168581419946888
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXN1 MDN1 FOXL2 POMGNT2 IARS1 PI4KA TRPS1 ANKRD17 POGZ NOL9 MRPL24 HNRNPL

1.46e-08857581225609649
Pubmed

Cloning of a gene that encodes a new member of the human cytotoxic cell protease family.

GZMH GZMB

2.73e-0625822193684
Pubmed

Rapid reuptake of granzyme B leads to emperitosis: an apoptotic cell-in-cell death of immune killer cells inside tumor cells.

GZMH GZMB

2.73e-06258224113190
Pubmed

A cluster of hematopoietic serine protease genes is found on the same chromosomal band as the human alpha/delta T-cell receptor locus.

GZMH GZMB

2.73e-0625822300587
Pubmed

Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

GZMH GZMB

2.73e-06258217179148
Pubmed

Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling.

GZMH GZMB

2.73e-06258233674611
Pubmed

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

GZMH GZMB

2.73e-0625827566124
Pubmed

Cloning of two genes that are specifically expressed in activated cytotoxic T lymphocytes.

GZMH GZMB

2.73e-0625823485287
Pubmed

Granzyme B-Mediated Activation-Induced Death of CD4+ T Cells Inhibits Murine Acute Graft-versus-Host Disease.

GZMH GZMB

2.73e-06258226392464
Pubmed

Granzyme B in injury, inflammation, and repair.

GZMH GZMB

2.73e-06258223099058
Pubmed

Differential cleavage of viral polypeptides by allotypic variants of granzyme B skews immunity to mouse cytomegalovirus.

GZMH GZMB

2.73e-06258232473350
Pubmed

A novel lineage-specific hypersensitive site is essential for position independent granzyme B expression in transgenic mice.

GZMH GZMB

2.73e-06258218222115
Pubmed

Granule-derived granzyme B mediates the vulnerability of human neurons to T cell-induced neurotoxicity.

GZMH GZMB

2.73e-06258221964027
Pubmed

Distinct patterns of cytolytic T-cell activation by different tumour cells revealed by Ca2+ signalling and granule mobilization.

GZMH GZMB

2.73e-06258227716898
Pubmed

Granzyme B deficiency promotes osteoblastic differentiation and calcification of vascular smooth muscle cells in hypoxic pulmonary hypertension.

GZMH GZMB

2.73e-06258229445095
Pubmed

Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma.

GZMH GZMB

2.73e-06258233737344
Pubmed

Mucinous cystadenocarcinoma of the breast harbours TRPS1 expressions and PIK3CA alterations.

PIK3CA TRPS1

2.73e-06258237983855
Pubmed

Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α.

GZMH GZMB

2.73e-06258222017873
Pubmed

Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death Program.

GZMH GZMB

2.73e-06258229107333
Pubmed

Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs.

GZMH GZMB

2.73e-06258218836177
Pubmed

Characterization of a novel, human cytotoxic lymphocyte-specific serine protease cDNA clone (CSP-C).

GZMH GZMB

2.73e-0625822402757
Pubmed

Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells.

GZMH GZMB

2.73e-06258216901729
Pubmed

Discordant regulation of granzyme H and granzyme B expression in human lymphocytes.

GZMH GZMB

2.73e-06258215069086
Pubmed

The herpes simplex virus type 1 latency-associated transcript can protect neuron-derived C1300 and Neuro2A cells from granzyme B-induced apoptosis and CD8 T-cell killing.

GZMH GZMB

2.73e-06258221177822
Pubmed

Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse.

GZMH GZMB

2.73e-06258232696761
Pubmed

Visualization of granzyme B-expressing CD8 T cells during primary and secondary immune responses to Listeria monocytogenes.

GZMH GZMB

2.73e-06258225367158
Pubmed

Requirement of MHC class I on radioresistant cells for granzyme B expression from CD8+ T cells in murine contact hypersensitivity.

GZMH GZMB

2.73e-06258229428817
Pubmed

New variants in the Enpp1 and Ptpn6 genes cause low BMD, crystal-related arthropathy, and vascular calcification.

PTPN6 ENPP1

2.73e-06258219419305
Pubmed

Granzyme B deficiency exacerbates lung inflammation in mice after acute lung injury.

GZMH GZMB

2.73e-06258223642129
Pubmed

Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes.

GZMH GZMB

2.73e-0625823518058
Pubmed

Structure and expression of a cluster of human hematopoietic serine protease genes found on chromosome 14q11.2.

GZMH GZMB

2.73e-0625822007574
Pubmed

Maternal diesel particle exposure promotes offspring asthma through NK cell-derived granzyme B.

GZMH GZMB

2.73e-06258232407293
Pubmed

Structure and evolutionary origin of the human granzyme H gene.

GZMH GZMB

2.73e-0625822049336
Pubmed

Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation.

GZMH GZMB

2.73e-06258225495009
Pubmed

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

GZMH GZMB

2.73e-0625828137431
Pubmed

Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.

GZMH GZMB

2.73e-06258222236998
Pubmed

Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection.

GZMH GZMB

2.73e-06258228798348
Pubmed

The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains.

GZMH GZMB

2.73e-06258217661907
Pubmed

Differential expression of granzyme B and C in murine cytotoxic lymphocytes.

GZMH GZMB

2.73e-06258219414782
Pubmed

Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability.

GZMH GZMB

2.73e-06258224791744
Pubmed

Activated mouse B cells lack expression of granzyme B.

GZMH GZMB

2.73e-06258222427643
Pubmed

A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis.

GZMH GZMB

2.73e-06258215356127
Pubmed

Immunoglobulin secretion by B1 cells: differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells.

FOXN1 IRF4

2.73e-06258221061433
Pubmed

Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.

GZMH GZMB

2.73e-06258216280358
Pubmed

Granzyme B plays a critical role in cytotoxic lymphocyte-induced apoptosis.

GZMH GZMB

2.73e-0625827493755
Pubmed

Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity.

GZMH GZMB

2.73e-06258219136373
Pubmed

Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis.

GZMH GZMB

2.73e-06258216405654
Pubmed

Granzyme B prevents aberrant IL-17 production and intestinal pathogenicity in CD4+ T cells.

GZMH GZMB

2.73e-06258234183776
Pubmed

Granzyme B Contributes to Barrier Dysfunction in Oxazolone-Induced Skin Inflammation through E-Cadherin and FLG Cleavage.

GZMH GZMB

2.73e-06258232504614
Pubmed

Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions.

GZMH GZMB

2.73e-06258215699143
Pubmed

Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression.

GZMH GZMB

2.73e-06258219915065
Pubmed

Granzyme B is dispensable in the development of diabetes in non-obese diabetic mice.

GZMH GZMB

2.73e-06258222792290
Pubmed

Organization of two genes encoding cytotoxic T lymphocyte-specific serine proteases CCPI and CCPII.

GZMH GZMB

2.73e-0625823264185
Pubmed

Inhibitory Effect of Zinc on Colorectal Cancer by Granzyme B Transcriptional Regulation in Cytotoxic T Cells.

GZMH GZMB

2.73e-06258237298408
Pubmed

Granzyme B inhibition reduces disease severity in autoimmune blistering diseases.

GZMH GZMB

2.73e-06258233436591
Pubmed

Genetic deletion of granzyme B does not confer resistance to the development of spontaneous diabetes in non-obese diabetic mice.

GZMH GZMB

2.73e-06258223663075
Pubmed

Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria.

GZMH GZMB

8.19e-06358221525386
Pubmed

Granzyme B is not required for regulatory T cell-mediated suppression of graft-versus-host disease.

GZMH GZMB

8.19e-06358219965675
Pubmed

Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner.

GZMH GZMB

8.19e-06358224414824
Pubmed

Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.

NALCN UNC79

8.19e-06358226708753
Pubmed

Granzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout mice.

GZMH GZMB

8.19e-06358223912712
Pubmed

Platelets induce apoptosis during sepsis in a contact-dependent manner that is inhibited by GPIIb/IIIa blockade.

GZMH GZMB

8.19e-06358222844498
Pubmed

A pro-survival role for the intracellular granzyme B inhibitor Serpinb9 in natural killer cells during poxvirus infection.

GZMH GZMB

8.19e-06358228722018
Pubmed

The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes.

GZMH GZMB

8.19e-06358228723565
Pubmed

Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.

GZMH GZMB

8.19e-06358216873683
Pubmed

Visualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme B.

GZMH GZMB

8.19e-06358223840635
Pubmed

Hop cleavage and function in granzyme B-induced apoptosis.

GZMH GZMB

8.19e-06358217005566
Pubmed

Granzyme B-mediated damage of CD8+ T cells impairs graft-versus-tumor effect.

GZMH GZMB

8.19e-06358223264653
Pubmed

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

GZMH GZMB

8.19e-06358220400962
Pubmed

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis.

GZMH GZMB

8.19e-06358216606695
Pubmed

The role of intrahepatic CD3+/CD4-/CD8- double negative T (DN T) cells in enhanced acetaminophen toxicity.

GZMH GZMB

8.19e-06358225168425
Pubmed

A novel and divergent role of granzyme A and B in resistance to helminth infection.

GZMH GZMB

8.19e-06358221248253
Pubmed

Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).

NALCN UNC79

8.19e-06358230167850
Pubmed

Autocrine DNA fragmentation of intra-epithelial lymphocytes (IELs) in mouse small intestine.

GZMH GZMB

8.19e-06358225750028
Pubmed

Bcl6 controls granzyme B expression in effector CD8+ T cells.

GZMH GZMB

8.19e-06358217125145
Pubmed

Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes.

GZMH GZMB

8.19e-06358235210420
Pubmed

Effect of genetically determined immunodeficiency on epidermal dendritic cell populations in C57BL/6J mice.

FOXN1 PTPN6

8.19e-0635822196000
Pubmed

Serine protease inhibitor 6 is required to protect dendritic cells from the kiss of death.

GZMH GZMB

8.19e-06358222227570
Pubmed

The major human and mouse granzymes are structurally and functionally divergent.

GZMH GZMB

8.19e-06358217116752
Pubmed

The orphan granzymes of humans and mice.

GZMH GZMB

8.19e-06358214499263
Pubmed

Serine protease inhibitor 6 protects iNKT cells from self-inflicted damage.

GZMH GZMB

8.19e-06358220543105
Pubmed

Murine Placental-Fetal Phosphate Dyshomeostasis Caused by an Xpr1 Deficiency Accelerates Placental Calcification and Restricts Fetal Growth in Late Gestation.

GZMH GZMB

8.19e-06358231498925
Pubmed

Granzyme-mediated regulation of host defense in the liver in experimental Leishmania donovani infection.

GZMH GZMB

8.19e-06358225452549
Pubmed

Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation.

GZMH GZMB

8.19e-06358222801574
Pubmed

CD4+ natural killer T cells potently augment aortic root atherosclerosis by perforin- and granzyme B-dependent cytotoxicity.

GZMH GZMB

8.19e-06358225398236
Pubmed

The human mast cell chymase gene (CMA1): mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression.

GZMH GZMB

8.19e-0635828468056
Pubmed

Analysis of GzmbCre as a Model System for Gene Deletion in the Natural Killer Cell Lineage.

GZMH GZMB

8.19e-06358225923440
Pubmed

Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis.

GZMH GZMB

8.19e-06358226610869
Pubmed

Collateral neuronal apoptosis in CNS gray matter during an oligodendrocyte-directed CD8(+) T cell attack.

GZMH GZMB

8.19e-06358219780193
Pubmed

The cytotoxic T cell proteinase granzyme B does not activate interleukin-1 beta-converting enzyme.

GZMH GZMB

8.19e-0635827798197
Pubmed

Granzyme A- and B-cluster deficiency delays acute lung injury in pneumovirus-infected mice.

GZMH GZMB

8.19e-06358220018616
Pubmed

A critical role for granzyme B, in addition to perforin and TNFalpha, in alloreactive CTL-induced mouse pancreatic beta cell death.

GZMH GZMB

8.19e-06358216436955
Pubmed

Long-range disruption of gene expression by a selectable marker cassette.

GZMH GZMB

8.19e-0635828917549
Pubmed

Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia.

GZMH GZMB

8.19e-06358226894590
Pubmed

Murine myeloid derived suppressor cells possess a range of suppressive mechanisms-Granzyme B is not among them.

GZMH GZMB

8.19e-06358235129637
Pubmed

Processing and activation of CMH-1 by granzyme B.

GZMH GZMB

8.19e-0635828631895
Pubmed

The course of Leishmania major infection in mice lacking granzyme-mediated mechanisms.

GZMH GZMB

8.19e-06358212182457
Pubmed

The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells.

GZMH GZMB

8.19e-06358212115618
Pubmed

Comparative molecular model building of two serine proteinases from cytotoxic T lymphocytes.

GZMH GZMB

8.19e-0635823237717
InteractionDAZL interactions

RBMS3 ANKRD17 ZCCHC2 LARP4 HNRNPL CPSF7

3.72e-06145586int:DAZL
InteractionTBC1D8 interactions

ENPP1 ADAM7 GZMH THOC2

1.51e-0552584int:TBC1D8
Cytoband4q13.3

ENAM ANKRD17

1.31e-03425824q13.3
GeneFamilyDyneins, axonemal

DNAH6 DNAH1

4.06e-0417322536
GeneFamilyForkhead boxes

FOXN1 FOXL2

2.62e-0343322508
GeneFamilyRNA binding motif containing

RBMS3 HNRNPL CPSF7

6.22e-03213323725
GeneFamilySH2 domain containing

PTPN6 SHC3

1.37e-02101322741
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN

UXS1 ENPP1 TRPS1 IRF4 CPD GLCCI1 CPSF7

2.42e-07198577M9234
CoexpressionGSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP

PTPN6 ACP3 ANKRD17 CPD ZC3H12C ECE1

4.67e-06199576M7274
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_NEUTROPHIL_CELL

NFE2 CPD ECE1 F5

1.31e-0566574M45733
CoexpressionGSE14699_NAIVE_VS_ACT_CD8_TCELL_DN

MDN1 RPP40 POGZ DZIP1 PAN3

3.96e-05175575M2940
CoexpressionGSE4590_SMALL_VS_LARGE_PRE_BCELL_UP

TRPS1 ANKRD17 CPD ZC3H12C DZIP1

3.96e-05175575M6872
CoexpressionHU_GENOTOXIC_DAMAGE_24HR

IARS1 GZMH GZMB

7.19e-0537573MM1170
CoexpressionGSE14308_TH2_VS_NATURAL_TREG_DN

HEG1 ACP3 PAN3 MRPL24 HNRNPL

7.29e-05199575M3369
CoexpressionGSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN

PTPN6 RPP40 ANKRD17 MRPL24 DNAH1

7.29e-05199575M8960
CoexpressionGSE17721_CTRL_VS_POLYIC_1H_BMDC_DN

ENAM ENPP1 TRPS1 CPD ZC3H12C

7.29e-05199575M3709
CoexpressionGSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN

GZMB IRF4 NOL9 ZCCHC2 LARP4

7.29e-05199575M6926
CoexpressionGSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN

PTPN6 AMER1 IRF4 ZCCHC2 CPSF7

7.46e-05200575M5995
CoexpressionGSE22033_UNTREATED_VS_MRL24_TREATED_MEF_UP

GGCT NFE2 NOL9 H6PD MRPL24

7.46e-05200575M7688
CoexpressionGSE13306_TREG_VS_TCONV_DN

PTPN6 UXS1 RPP40 GZMH PAN3

7.46e-05200575M3230
CoexpressionGSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN

PTPN6 ENPP1 ACP3 GZMB ECE1

7.46e-05200575M7276
CoexpressionNAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_UP

IARS1 TRPS1 ANKRD17 IRF4 CPD MRPL24 F5

7.62e-05477577M40930
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

HEG1 AMER1 FOXL2 NALCN RBMS3 ENPP1 LRRTM4 TRPS1 CPD ECE1 THOC2

8.12e-067905811gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

HEG1 AMER1 FOXL2 LRRTM4 SYN2 ANKRD17 CPD ECE1 LARP4 THOC2

5.23e-057955810gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

HEG1 AMER1 NALCN RBMS3 PIK3CA ENPP1 TRPS1 CPD ECE1 THOC2

5.57e-058015810gudmap_developingGonad_e14.5_ epididymis_1000
ToppCellT_cells-TFH-like_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

RBMS3 FZD3 TRPS1 IRF4 ZC3H12C F5

1.20e-07178586e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCellsevere-Myeloid-pDC|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ENAM RBMS3 FZD3 GZMB IRF4

2.17e-061615859e8e8ac11f7fb8c8697357c21034b613f191db2b
ToppCellT_cells-TFH-like_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

RBMS3 FZD3 TRPS1 F5 GLCCI1

2.37e-06164585b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPP40 GZMH GZMB POGZ DSEL

2.59e-061675853b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FZD3 ENPP1 ACP3 SYN2 ECE1

2.75e-06169585e3410ccb3f85811c75694e286115803911169a2f
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FZD3 ENPP1 ACP3 SYN2 ECE1

2.75e-06169585a4f610d07c3ba5537f4497f523669b914f7eddc1
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

ENAM GZMB SLITRK5 OVOS2 IRF4

3.17e-06174585be8227398300711ccda5ecc41ad34064bb246b19
ToppCellT_cells-Tph_and_Tfh|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FZD3 TRPS1 IRF4 F5 GLCCI1

3.35e-0617658556c055488e34605d32562571a2fee621b47c9441
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

LILRB2 GZMB SLITRK5 OVOS2 IRF4

3.45e-0617758543e1d0d3cf8f0c02e67d91f8dd1761df23d59e07
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPP40 DZIP1 UNC79 SHC3 DNAH1

3.64e-06179585b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENAM GZMB SLITRK5 IRF4 GLCCI1

3.64e-0617958529b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

NALCN RBMS3 LRRTM4 DZIP1 ECE1

3.74e-0618058501f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENAM FZD3 GZMB SLITRK5 IRF4

4.28e-06185585f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENAM FZD3 GZMB SLITRK5 IRF4

4.28e-061855853cb816fc9541c04b4436e21d984216cfbbacff98
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

UXS1 TRPS1 ZC3H12C F5 GLCCI1

4.28e-06185585e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENAM FZD3 GZMB SLITRK5 IRF4

4.28e-06185585c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCellMild-Lymphoid-pDC|Mild / Condition, Lineage, Cell class and cell subclass

ENAM FZD3 GZMB SLITRK5 IRF4

4.39e-061865857fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ENAM FZD3 GZMB SLITRK5 IRF4

4.39e-06186585b031f4e6867b6200b85f43276a34749bf5f4603f
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ENAM FZD3 GZMB SLITRK5 IRF4

4.39e-06186585d2fbf53aac905c9896272ec5c2db28ee1a60f4be
ToppCellMild-Lymphoid-pDC-|Mild / Condition, Lineage, Cell class and cell subclass

ENAM FZD3 GZMB SLITRK5 IRF4

4.39e-061865851d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ENAM FZD3 GZMB SLITRK5 IRF4

4.39e-0618658579aedd5aed72509a4925e9f6cb43bc0c798c86f5
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 HEG1 PAN3 GLCCI1 HNRNPL

4.51e-06187585b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 HEG1 PAN3 GLCCI1 HNRNPL

4.51e-061875853ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellIPF-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

UXS1 TRPS1 ZC3H12C F5 GLCCI1

4.75e-061895857a260485c2a7c743c14d048e5e480ae0a9b8e32c
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ENAM PTPN6 NFE2 GZMB IRF4

4.99e-0619158547f20686001f945bc31d5a0b974958e4009edb34
ToppCell10x5'-bone_marrow|World / Manually curated celltypes from each tissue

NFE2 LILRB2 GZMH GZMB HNRNPL

5.12e-0619258534777fa7dc001b6d601376a23aab995e2cec043c
ToppCellcontrol-pDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ENAM RBMS3 FZD3 GZMB IRF4

5.25e-0619358530a6559c9a9e8941861cb259b4836acccc427e68
ToppCellSigmoid-(4)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

NFE2 LILRB2 ACP3 SYN2 F5

6.25e-062005857f3920a0434d5199c6c8f0b3064a305bb0d87b60
ToppCellSigmoid-Monocyte-Monocyte|Sigmoid / Region, Cell class and subclass

NFE2 LILRB2 ACP3 SYN2 F5

6.25e-06200585010ca36970cb8894bdbca08779c0ecf56be22fc9
ToppCellSigmoid-Monocyte|Sigmoid / Region, Cell class and subclass

NFE2 LILRB2 ACP3 SYN2 F5

6.25e-06200585c41bd6ec0f2262fce5cadb37a400d487e6662f49
ToppCellSigmoid-(4)_Monocyte-(40)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

NFE2 LILRB2 ACP3 SYN2 F5

6.25e-06200585576c0a1098e6a934448705de3673ef798fcf1b26
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B1|390C / Donor, Lineage, Cell class and subclass (all cells)

FOXL2 GZMH GZMB SLITRK5

1.34e-051115849972d31966b059aa3446407b73b714b0b06ec815
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB LRRTM4 MAMSTR

3.53e-0514258461eefa32926a057e53747633bf4a81f09ea721c5
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RBMS3 RPP40 PI4KA H6PD

3.73e-051445841b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCelldroplet-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPN6 NFE2 ACP3 F5

4.73e-05153584ce6e462ce4dbaf9d265f1f9e2f791efbba8c1dd0
ToppCelldroplet-Lung-3m-Hematologic-myeloid-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPN6 NFE2 ACP3 F5

4.73e-051535849dba38574908f31a1194b8a339868f5e4be1be71
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

GZMB SLITRK5 OVOS2 IRF4

5.10e-0515658419472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCellfacs-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 CPD DNAH6 F5

5.10e-05156584034d4359359a44c205c6931f38a375271ac2752b
ToppCellfacs-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 CPD DNAH6 F5

5.10e-051565842a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCellfacs-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 CPD DNAH6 F5

5.10e-0515658421267718d3a3dc19988663b6846aed8bb3eae836
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

GZMB SLITRK5 OVOS2 IRF4

5.36e-051585842af7beb48272e5368d9ba6b80f08d47ab8556c08
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Gpr88_(Medial_entorrhinal_cortex)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CPNE9 NFE2 ADAM7

5.37e-0556583a310f50724ada8da92257c54b18d9214d7415010
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Gpr88_(Medial_entorrhinal_cortex)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CPNE9 NFE2 ADAM7

5.37e-05565834740900fffc892200f3e2480328eb43cb6d19f20
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB IRF4 GLCCI1

5.63e-051605848e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB IRF4 GLCCI1

5.63e-0516058450d4f867d021abcfeb49e6812bcfd5bb57466a31
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB IRF4 GLCCI1

5.63e-051605840f15f895f11dcabb73df79b26bfc4947f38435a7
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB IRF4 GLCCI1

5.63e-051605847d004bfe42707605b3851cb2319126acda4d4802
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ENAM ENPP1 GZMB IRF4

5.91e-0516258486a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCellsevere-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ENAM FZD3 GZMB IRF4

6.49e-05166584ae38850fde549b8dd6fb12f0ef80b428ade50485
ToppCellInfluenza_Severe-pDC|Influenza_Severe / Disease group and Cell class

ENAM FZD3 SLITRK5 IRF4

6.49e-05166584b43a5cd4d28118cf6e56a435deb8ea9435608a90
ToppCell367C-Myeloid-Dendritic-pDC|367C / Donor, Lineage, Cell class and subclass (all cells)

ENAM LILRB2 GZMB IRF4

6.64e-05167584650de8cd5df070639b8aa292aacead739cfdb02c
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPS8 PTPN6 GGCT NFE2

6.96e-05169584305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell343B-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ENAM FZD3 GZMB IRF4

6.96e-05169584632aa3ab39ec87bafcefec6cddf71129a054d3b0
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|metastatic_Brain / Location, Cell class and cell subclass

GZMB SLITRK5 OVOS2 IRF4

6.96e-0516958471f6761b9927f352e0ccc221ca373319915f4184
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NALCN DNAH6 UNC79 DNAH1

6.96e-0516958412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

EPS8 UXS1 LRRTM4 ECE1

7.12e-05170584d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

EPS8 UXS1 GLCCI1 SHC3

7.12e-05170584269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellfacs|World / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UXS1 HEG1 PAN3 ECE1

7.28e-05171584bb71e816dde44fda6af0ad98d979be9f8740fda6
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

EPS8 RBMS3 LRRTM4 ECE1

7.28e-05171584080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellfacs|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UXS1 HEG1 PAN3 ECE1

7.28e-051715845bcb96ed7fc15548f2dc9cf47482f890640cb39c
ToppCell368C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GZMH GZMB IRF4 DSEL

7.28e-05171584714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCellChildren_(3_yrs)-Immune-dendritic_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ENAM ENPP1 GZMB IRF4

7.28e-051715846a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCellfacs|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UXS1 HEG1 PAN3 ECE1

7.45e-05172584a2d0a64ebf09d219a07d6bbad1056bad6d46b9be
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th1|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GZMH GZMB TRPS1 DNAH6

7.45e-05172584c0c9a3f5b5fb942b049bc159fd9f21b5b706edd2
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP1 LRRTM4 MAMSTR IRF4

7.79e-05174584cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ENAM PI4KA GZMB IRF4

7.96e-0517558437c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell343B-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ENAM FZD3 GZMB IRF4

7.96e-05175584b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ENAM GZMB SLITRK5 IRF4

7.96e-0517558497fe431f224b592b3076632d101e19136c138dcc
ToppCellmild-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ENAM FZD3 GZMB IRF4

8.14e-0517658459a9c262c252b7d220a025837922d98e9d6b0a24
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB IRF4 GLCCI1

8.14e-051765846b1cf1e98b4509e87f9eea827fa7090ce1e504f1
ToppCellCF-Lymphoid-pDC|CF / Disease state, Lineage and Cell class

FZD3 GZMB SLITRK5 IRF4

8.14e-05176584dd1e529a9e413bcaab43584afbe059e1464ffb53
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NALCN ENPP1 LRRTM4 IRF4

8.32e-051775849ec7f1e64312d26d434b3312b58386715dbad644
ToppCellControl-Myeloid-pDC|Control / Disease state, Lineage and Cell class

ENAM GZMB IRF4 GLCCI1

8.32e-051775843940663bb5b45b2ca9f772550380a516c53e410b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NALCN ENPP1 LRRTM4 IRF4

8.32e-05177584016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellControl-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENAM GZMB IRF4 GLCCI1

8.32e-05177584e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCellCOPD-Myeloid-pDC|COPD / Disease state, Lineage and Cell class

ENAM GZMB SLITRK5 IRF4

8.32e-05177584415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB IRF4 GLCCI1

8.51e-05178584f94e306b9550f3d1b5de0bb806790c17823d439e
ToppCellfacs|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UXS1 HEG1 PAN3 ECE1

8.69e-051795848001db3044e8657980e24422377c4fdb0d7b323e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPS8 UXS1 GLCCI1 SHC3

8.69e-05179584815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

FOXN1 EPS8 NALCN SHC3

8.69e-051795841526a130565a97c291a25a7a988089bffc1515c1
ToppCellIPF-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENAM GZMB IRF4 GLCCI1

8.88e-051805840f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCellmoderate-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MDN1 FZD3 GZMB IRF4

8.88e-051805841d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 HEG1 RBMS3 OVOS2

9.07e-051815842f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CPNE9 FZD3 GZMB IRF4

9.27e-051825849bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NALCN PI4KA MAMSTR F5

9.27e-051825841923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CPNE9 FZD3 GZMB IRF4

9.27e-051825844602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NALCN PI4KA MAMSTR F5

9.27e-0518258469ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FZD3 GZMH GZMB DSEL

9.47e-05183584983ca1342ddd365e1f1df32a456394b002b10e41
ToppCellnormal_Lung-B_lymphocytes-GrB-secreting_B_cells|normal_Lung / Location, Cell class and cell subclass

GZMB SLITRK5 OVOS2 IRF4

9.47e-05183584c930b957d16f9b0904b6c424acd914532e5cc137
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NFE2 CPD ECE1 F5

9.67e-051845847ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ENPP1 ACP3 IRF4 SHC3

9.67e-051845840a26bcc6610f756939e32a4d6dfeebcbf3a1db86
ToppCellLeuk-UTI-Other-RBC|Leuk-UTI / Disease, Lineage and Cell Type

ENAM GZMB SLITRK5 OVOS2

9.87e-051855845b5dd856d6efc0539d92533cff134bbc3f98be45
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPS8 UXS1 LRRTM4 ECE1

9.87e-05185584a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 ACP3 IRF4 SHC3

9.87e-05185584fec16a5e527fdef32d25957451b6e8ee9796cafd
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMH GZMB IRF4 GLCCI1

9.87e-05185584f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HEG1 GZMH GZMB DNAH6

9.87e-05185584593eceb3dfcc662c892a840ba29ab687c6886c01
ToppCellHealthy_donor-pDC|Healthy_donor / disease group, cell group and cell class (v2)

ENAM RBMS3 FZD3 IRF4

9.87e-051855847fbb55cbdb39bdecb6063c8ba9776ab06c2666e8
ToppCellcritical-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ENAM GZMB IRF4 GLCCI1

9.87e-051855844a5d1d0a757f1f4fdb911be96ed90b52182c25f0
ToppCellLeuk-UTI-Other|Leuk-UTI / Disease, Lineage and Cell Type

ENAM GZMB SLITRK5 OVOS2

9.87e-05185584895e8087e97ac0eab3446385e6e0dd24bea7f42c
ToppCellproximal-3-Hematologic-Myeloid_Dendritic_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ENPP1 IRF4 ZCCHC2 UNC79

1.01e-04186584c920dffd24f051b54d8b48f801fffc928d99e135
Diseasegranzyme b measurement

GZMH GZMB

2.12e-054562EFO_0020418
Diseasesquamous cell carcinoma

RPP40 TRPS1 IRF4

2.85e-0467563EFO_0000707
Diseaseactinic keratosis

TRPS1 IRF4

3.17e-0414562EFO_0002496
Diseasemonocyte percentage of leukocytes

NFE2 PI4KA TRPS1 IRF4 PAN3 GLCCI1 SHC3

4.50e-04731567EFO_0007989
Diseaselip morphology measurement

POMGNT2 RBMS3 LRRTM4 DNAH1

4.62e-04189564EFO_0007845
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

TRPS1 MAMSTR SYN2

9.73e-04102563EFO_0004329, EFO_0004611
Diseasenecrotizing enterocolitis

TRPS1 SYN2

1.20e-0327562EFO_0003928
Diseaseinterleukin 5 measurement

POMGNT2 ECE1

1.30e-0328562EFO_0008185
Diseasekeratinocyte carcinoma

RPP40 TRPS1 IRF4

1.48e-03118563EFO_0010176
DiseaseHirschsprung Disease

FZD3 ECE1

1.59e-0331562C0019569
Diseasegranulocyte percentage of myeloid white cells

NFE2 TRPS1 PAN3 GLCCI1

1.69e-03268564EFO_0007997
Diseasecutaneous squamous cell carcinoma

TRPS1 IRF4

1.80e-0333562EFO_1001927

Protein segments in the cluster

PeptideGeneStartEntry
SPASPPNYMYNPIKT

UXS1

161

Q8NBZ7
YTPPRSQPMNKHLFV

C1orf140

16

Q5VVS0
KPTCMLNIPFPYNFH

ADAM7

386

Q9H2U9
PHPAYNPKNFSNDIM

GZMB

96

P10144
PHPAYNPKNFSNDIM

GZMH

96

P20718
YPRPNMNLGYHPTTS

AMER1

416

Q5JTC6
PKYASSPKPNNSYMF

GLCCI1

401

Q86VQ1
NATYPMPTAKEHYPV

ANKRD17

2026

O75179
YLQTKQSYAPAPHPM

RBMS3

21

Q6XE24
PPDTYMKASAPYNHH

CPSF7

306

Q8N684
PFTHLRTPQKMVYYG

NOL9

361

Q5SY16
MVKPDGPYDFYQHPN

MDN1

3706

Q9NU22
HMKPLPYYSYDQPVI

LRRTM4

521

Q86VH4
TPYPSLPAQQVHNYM

IRF4

156

Q15306
PAQKPPYSYVALIAM

FOXL2

51

P58012
SMYPPHPLTAQYGVK

PI4KA

1626

P42356
IHEYPKYQAEFPMSP

LILRB2

371

Q8N423
LMTNYESAPPSPQYK

GGCT

126

O75223
KNMRPVYPTKTFPNH

ENPP1

246

P22413
QMSPYAEYPKNPRSQ

HEG1

1291

Q9ULI3
PDHYTPYKTLAMLPG

POMGNT2

371

Q8NAT1
PKPLYLETENYGPMH

OVOS2

681

Q6IE36
LNSPHSRAMYVYPPN

PIK3CA

156

P42336
YRNETQHEPYPLMLP

ACP3

331

P15309
PTAPHVAYMQPKANA

PAN3

426

Q58A45
RMYITTKLPNPHYTP

DNAH1

3321

Q9P2D7
RFYMTTKMPNPHYLP

DNAH6

3166

Q9C0G6
GNPLQPTSLHYMSPY

CPNE9

311

Q8IYJ1
KNMYPNEYFPHGITN

CPD

721

O75976
YASPVFMQPVYNPHQ

LARP4

301

Q71RC2
ESKPRGNLTYHQYMP

MAMSTR

91

Q6ZN01
YHIPCPYQVTQMSRP

FZD3

461

Q9NPG1
FLNHYQMKNPNGPYP

HNRNPL

561

P14866
YKLPHSEGYMPVPNF

ENAM

471

Q9NRM1
YPLQMKSSGPPSYFI

EMC7

136

Q9NPA0
PYTHTIQKQRMEYGP

EPS8

601

Q12929
WYNTSNPLPYEHMKP

DDHD1

686

Q8NEL9
TPPMVNAYYSPTKNE

ECE1

561

P42892
IPYYNIHPMPVHLQQ

H6PD

646

O95479
VMLSNPTYYLPPPKH

DSEL

96

Q8IZU8
PYSYGNMAIPVSKPL

NFE2

96

Q16621
MNTGPYYFVKNLPLH

RPP40

61

O75818
YYPNHKEMLTLPTFP

SYN2

251

Q92777
KNMASRPYSIYPHGV

F5

436

P12259
YYQTNVPPSKPVAMT

TAF1L

1301

Q8IZX4
YQPPLQHMYCSSQPP

FOXN1

216

O15353
HDRNVKNMYPPPSFP

POGZ

866

Q7Z3K3
GSDHPYYNSIPSKMP

SHC3

336

Q92529
GSMPYAQVHYPFENK

IARS1

531

P41252
SKVTLPPHYRYGMSP

MRPL24

11

Q96A35
SMPFQKHVYYPLASG

DZIP1

11

Q86YF9
DPLNSPKYQHISFMP

ZCCHC2

706

Q9C0B9
SPIEKYMRPAKHPNY

TRPS1

1066

Q9UHF7
DQMPPYYAASHKLIA

THOC2

366

Q8NI27
YIPHPLGHMCKNPIY

SLITRK5

751

O94991
YGNITYPPAMKNAHA

PTPN6

536

P29350
TKNHGTPMPYEQYPK

ZC3H12C

566

Q9C0D7
PSQVKPPAVQMLFHY

UNC79

266

Q9P2D8
NTPMTFEHYPPLQYV

NALCN

56

Q8IZF0