Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5A KDM5C KDM5D

6.54e-076653GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5A KDM5C KDM5D

1.82e-068653GO:0032453
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5A KDM5C KDM5D

1.02e-0428653GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5A KDM5C KDM5D

1.39e-0431653GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5A KDM5C KDM5D

1.53e-0432653GO:0140457
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A3

2.17e-047652GO:1990239
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP1A1 ATP1A3 ATP2B4

2.18e-0436653GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP1A1 ATP1A3 ATP2B4

2.18e-0436653GO:0015662
GeneOntologyMolecularFunctiondemethylase activity

KDM5A KDM5C KDM5D

3.96e-0444653GO:0032451
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A3

4.62e-0410652GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A3

4.62e-0410652GO:0005391
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A3

5.63e-0411652GO:0008556
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RASGRP4 SBF1 RGL3 DENND4B DENND4C

9.32e-04231655GO:0005085
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP1A1 ATP1A3 ATP2B4

1.09e-0362653GO:0019829
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5A KDM5C KDM5D

1.25e-0365653GO:0016706
GeneOntologyMolecularFunctionintegrin binding

ICAM3 ADAMTS13 ITGA2B SVEP1

2.55e-03175654GO:0005178
GeneOntologyMolecularFunctioncalcium ion binding

SYT15 RASGRP4 DSG1 DLL4 CDHR5 ADAMTS13 SVEP1 NOTCH4

2.88e-03749658GO:0005509
GeneOntologyMolecularFunctionmolecular function inhibitor activity

GPIHBP1 SBF1 KDM5A BIRC6 ATP2B4 WNK4 PPP1R16A

3.17e-03596657GO:0140678
GeneOntologyMolecularFunctionNotch binding

DLL4 NOTCH4

3.47e-0327652GO:0005112
GeneOntologyMolecularFunctiondioxygenase activity

KDM5A KDM5C KDM5D

4.02e-0398653GO:0051213
GeneOntologyCellularComponentphotoreceptor inner segment membrane

ATP1A1 ATP1A3

5.51e-054642GO:0060342
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A1 ATP1A3

5.97e-0412642GO:0005890
GeneOntologyCellularComponentapical plasma membrane

SHROOM3 GPIHBP1 DSG1 UPK1A CDHR5 ATP1A1 SLC44A4

7.04e-04487647GO:0016324
DomainLys_sp_deMease-like_dom

KDM5A KDM5C KDM5D

1.39e-074623IPR013637
DomainPLU-1

KDM5A KDM5C KDM5D

1.39e-074623PF08429
Domainzf-C5HC2

KDM5A KDM5C KDM5D

3.47e-075623PF02928
DomainZnf_C5HC2

KDM5A KDM5C KDM5D

3.47e-075623IPR004198
DomainJmjN

KDM5A KDM5C KDM5D

4.11e-0610623SM00545
DomainJMJN

KDM5A KDM5C KDM5D

4.11e-0610623PS51183
DomainJmjN

KDM5A KDM5C KDM5D

4.11e-0610623PF02375
DomainJmjN

KDM5A KDM5C KDM5D

4.11e-0610623IPR003349
Domain-

KDM5A KDM5C KDM5D

1.54e-05156231.10.150.60
DomainBRIGHT

KDM5A KDM5C KDM5D

1.54e-0515623SM00501
DomainARID_dom

KDM5A KDM5C KDM5D

1.54e-0515623IPR001606
DomainARID

KDM5A KDM5C KDM5D

1.54e-0515623PS51011
DomainARID

KDM5A KDM5C KDM5D

1.54e-0515623PF01388
DomainUDENN

SBF1 DENND4B DENND4C

1.89e-0516623PS50946
DomainDDENN

SBF1 DENND4B DENND4C

1.89e-0516623PS50947
DomainDENN

SBF1 DENND4B DENND4C

1.89e-0516623SM00799
Domain-

ATP1A1 ATP1A3 ATP2B4

1.89e-05166231.20.1110.10
DomaindDENN

SBF1 DENND4B DENND4C

1.89e-0516623SM00801
DomainDENN

SBF1 DENND4B DENND4C

1.89e-0516623PF02141
DomaindDENN_dom

SBF1 DENND4B DENND4C

1.89e-0516623IPR005112
DomainuDENN_dom

SBF1 DENND4B DENND4C

1.89e-0516623IPR005113
DomaindDENN

SBF1 DENND4B DENND4C

1.89e-0516623PF03455
DomainDENN

SBF1 DENND4B DENND4C

1.89e-0516623PS50211
DomainDENN_dom

SBF1 DENND4B DENND4C

1.89e-0516623IPR001194
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A3 ATP2B4

1.89e-0516623IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A3 ATP2B4

2.29e-0517623IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A3 ATP2B4

2.29e-0517623PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A3 ATP2B4

2.74e-0518623PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A3 ATP2B4

2.74e-0518623SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A3 ATP2B4

3.25e-0519623IPR004014
DomainJmjC

KDM5A KDM5C KDM5D

6.71e-0524623PF02373
DomainEGF

FRAS1 FCGBP DLL4 HYAL3 SVEP1 NOTCH4

1.27e-04235626SM00181
DomainP-type_ATPase_IIC

ATP1A1 ATP1A3

1.61e-046622IPR005775
DomainJMJC

KDM5A KDM5C KDM5D

1.61e-0432623PS51184
DomainJmjC_dom

KDM5A KDM5C KDM5D

1.61e-0432623IPR003347
DomainEGF-like_dom

FRAS1 FCGBP DLL4 HYAL3 SVEP1 NOTCH4

1.74e-04249626IPR000742
DomainJmjC

KDM5A KDM5C KDM5D

1.77e-0433623SM00558
DomainATPase_P-typ_cyto_domN

ATP1A1 ATP1A3 ATP2B4

2.11e-0435623IPR023299
DomainP_typ_ATPase

ATP1A1 ATP1A3 ATP2B4

2.30e-0436623IPR001757
DomainATPase_P-typ_P_site

ATP1A1 ATP1A3 ATP2B4

2.30e-0436623IPR018303
DomainATPASE_E1_E2

ATP1A1 ATP1A3 ATP2B4

2.30e-0436623PS00154
DomainATPase_P-typ_transduc_dom_A

ATP1A1 ATP1A3 ATP2B4

2.50e-0437623IPR008250
DomainE1-E2_ATPase

ATP1A1 ATP1A3 ATP2B4

2.50e-0437623PF00122
DomainPPR

DENND4B DENND4C

3.00e-048622PS51375
DomainuDENN

SBF1 DENND4B

9.62e-0414622SM00800
DomainuDENN

SBF1 DENND4B

1.11e-0315622PF03456
DomainZinc_finger_PHD-type_CS

KDM5A KDM5C KDM5D

1.31e-0365623IPR019786
DomainVWC_out

FRAS1 FCGBP

1.79e-0319622SM00215
DomainGrowth_fac_rcpt_

FRAS1 DLL4 SVEP1 NOTCH4

1.79e-03156624IPR009030
DomainPHD

KDM5A KDM5C KDM5D

1.98e-0375623PF00628
DomainHAD-like_dom

ATP1A1 ATP1A3 ATP2B4

2.30e-0379623IPR023214
DomainZnf_PHD-finger

KDM5A KDM5C KDM5D

2.30e-0379623IPR019787
DomainRas-like_Gua-exchang_fac_N

RASGRP4 RGL3

2.40e-0322622IPR000651
DomainRASGEF_NTER

RASGRP4 RGL3

2.40e-0322622PS50212
DomainPentatricopeptide_repeat

DENND4B DENND4C

2.62e-0323622IPR002885
DomainPHD

KDM5A KDM5C KDM5D

3.23e-0389623SM00249
DomainRASGEF

RASGRP4 RGL3

3.35e-0326622PS00720
DomainZnf_PHD

KDM5A KDM5C KDM5D

3.44e-0391623IPR001965
DomainhEGF

SVEP1 NOTCH4

3.88e-0328622PF12661
DomainZF_PHD_2

KDM5A KDM5C KDM5D

3.88e-0395623PS50016
DomainZF_PHD_1

KDM5A KDM5C KDM5D

4.00e-0396623PS01359
DomainRASGEF_CAT

RASGRP4 RGL3

4.16e-0329622PS50009
DomainRasGEF

RASGRP4 RGL3

4.44e-0330622PF00617
Domain-

RASGRP4 RGL3

4.44e-03306221.10.840.10
DomainRas_GEF_dom

RASGRP4 RGL3

4.44e-0330622IPR023578
DomainRASGEF_cat_dom

RASGRP4 RGL3

4.44e-0330622IPR001895
DomainRasGEF

RASGRP4 RGL3

4.44e-0330622SM00147
DomainASX_HYDROXYL

DLL4 SVEP1 NOTCH4

4.48e-03100623PS00010
Domain-

ATP1A1 ATP1A3

5.04e-03326223.40.1110.10
Domain-

ATP1A1 ATP1A3

5.04e-03326222.70.150.10
DomainEGF-type_Asp/Asn_hydroxyl_site

DLL4 SVEP1 NOTCH4

5.27e-03106623IPR000152
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5A KDM5C KDM5D

1.19e-0429473MM14934
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

FOXO6 FOXO4

4.81e-0410472M27095
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

FOXO6 FOXO4

4.81e-0410472MM14778
PathwayREACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY

TAB2 ALPK1

5.87e-0411472M29827
PathwayREACTOME_NOTCH4_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

DLL4 NOTCH4

5.87e-0411472M27882
PathwayREACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY

TAB2 ALPK1

5.87e-0411472MM15668
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5A KDM5C KDM5D

6.10e-0450473M27232
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

FOXO6 FOXO4

7.03e-0412472MM15657
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

FOXO6 FOXO4

7.03e-0412472M27939
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A1 ATP1A3 ATP2B4

7.65e-0454473M27460
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A1 ATP1A3 ATP2B4

7.65e-0454473MM15202
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP1A1 ATP1A3 ATP2B4

8.07e-0455473M971
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

DLL4 NOTCH4

8.29e-0413472M47423
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP1A1 ATP1A3 ATP2B4

8.96e-0457473MM15643
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5A KDM5C KDM5D

2.73e-08467316541399
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5A KDM5C KDM5D

1.93e-061367324619213
Pubmed

Breast cancer stem cells: something out of notching?

DLL4 NOTCH4

3.66e-06267221045140
Pubmed

Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.

ATP1A1 ATP1A3

3.66e-06267221498719
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

3.66e-06267210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

3.66e-06267216416087
Pubmed

The Ca2+ export pump PMCA clears near-membrane Ca2+ to facilitate store-operated Ca2+ entry and NFAT activation.

NFATC1 ATP2B4

3.66e-06267231594854
Pubmed

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.

ATP1A1 ATP1A3

3.66e-06267211546672
Pubmed

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

ATP1A1 ATP1A3

3.66e-06267224391932
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

3.66e-06267232081420
Pubmed

The role of FOXO4/NFAT2 signaling pathway in dysfunction of human coronary endothelial cells and inflammatory infiltration of vasculitis in Kawasaki disease.

NFATC1 FOXO4

3.66e-06267236700213
Pubmed

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

ATP1A1 ATP1A3

3.66e-06267223761886
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

3.66e-0626729060413
Pubmed

The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.

ATP1A1 ATP1A3

3.66e-0626723030810
Pubmed

Notch signaling in primary endothelial cells.

DLL4 NOTCH4

3.66e-06267212814948
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

3.66e-0626727524912
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

QSOX1 FCGBP ICAM3 CDHR5 ADAMTS13 ITGA2B

1.05e-0525767616335952
Pubmed

Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation.

DLL4 ITGA2B

1.10e-05367232149421
Pubmed

The calcium pump PMCA4 prevents epithelial-mesenchymal transition by inhibiting NFATc1-ZEB1 pathway in gastric cancer.

NFATC1 ATP2B4

1.10e-05367232860837
Pubmed

Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

ATP1A1 ATP1A3

1.10e-0536722822726
Pubmed

Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.

ATP1A1 ATP1A3

1.10e-05367230819023
Pubmed

Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.

DENND4B DENND4C

1.10e-05367212906859
Pubmed

Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.

ATP1A1 ATP1A3

1.10e-05367227836549
Pubmed

Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.

ATP1A1 ATP1A3

1.10e-05367226373354
Pubmed

Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans.

FOXO6 FOXO4

1.10e-05367221388494
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

1.10e-0536727544442
Pubmed

Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.

ATP1A1 ATP1A3

1.10e-05367217947306
Pubmed

RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.

KDM5A KDM5C

1.10e-05367217320161
Pubmed

KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas.

KDM5A KDM5C

1.10e-05367237880235
Pubmed

Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.

KDM5A KDM5C

1.10e-05367226645689
Pubmed

Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.

ATP1A1 ATP1A3

1.10e-05367219058785
Pubmed

Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.

ATP1A1 ATP1A3

1.10e-05367228465228
Pubmed

Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.

ATP1A1 ATP1A3

1.10e-0536728203495
Pubmed

Delta-like 4/Notch pathway is differentially regulated in benign and malignant thyroid tissues.

DLL4 NOTCH4

1.10e-05367222066479
Pubmed

Na,K-ATPase and the role of alpha isoforms in behavior.

ATP1A1 ATP1A3

1.10e-05367218044013
Pubmed

Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.

ATP1A1 ATP1A3

1.10e-05367226988030
Pubmed

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.

ATP1A1 ATP1A3

1.10e-05367226911348
Pubmed

The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions.

DLL4 NOTCH4

1.10e-05367216951162
Pubmed

Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.

KDM5A KDM5C

1.10e-05367238230606
Pubmed

Calcium and calcineurin-NFAT signaling regulate granulocyte-monocyte progenitor cell cycle via Flt3-L.

FLT3LG NFATC1

1.10e-05367225100642
Pubmed

Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.

ATP1A1 ATP1A3

1.10e-05367225994790
Pubmed

The vascular delta-like ligand-4 (DLL4)-Notch4 signaling correlates with angiogenesis in primary glioblastoma: an immunohistochemical study.

DLL4 NOTCH4

1.10e-05367226472724
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TTC7B SBF1 INF2 DENND4B TRIOBP ATP1A1 ATP2B4

1.69e-0542167736976175
Pubmed

Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.

ATP1A1 ATP1A3

2.19e-05467221731499
Pubmed

The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.

ATP1A1 ATP1A3

2.19e-05467212458206
Pubmed

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

ATP1A1 ATP1A3

2.19e-05467221849490
Pubmed

Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain.

FOXO6 FOXO4

2.19e-05467216326148
Pubmed

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.

FLT3LG DLL4

2.19e-05467222547652
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5C KDM5D

2.19e-05467217320160
Pubmed

Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.

ATP1A1 ATP1A3

2.19e-05467217446412
Pubmed

Conserved synteny in rat and mouse for a blood pressure QTL on human chromosome 17.

ITGA2B WNK4

2.19e-05467212052840
Pubmed

Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties.

DLL4 NOTCH4

2.19e-05467236376768
Pubmed

Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.

ATP1A1 ATP1A3

2.19e-05467211591489
Pubmed

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

ATP1A1 ATP1A3

2.19e-05467219751721
Pubmed

Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.

ATP1A1 ATP1A3

2.19e-05467219376779
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5C KDM5D

2.19e-05467232732223
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5C KDM5D

2.19e-0546727951230
Pubmed

Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.

ATP1A1 ATP1A3

2.19e-05467217234593
Pubmed

Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.

ATP1A1 ATP1A3

2.19e-0546722887455
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP1A1 ATP1A3 ATP2B4

2.41e-052967315071553
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM5A KDM5C KDM5D

3.58e-053367326864203
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

DLL4 NOTCH4

3.64e-05567221726900
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A1 ATP1A3

3.64e-0556723035563
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

DLL4 NOTCH4

3.64e-05567223675950
Pubmed

CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS.

DLL4 NOTCH4

3.64e-05567217576775
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

SBF1 DENND4B DENND4C

5.07e-053767320937701
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP1A3

5.46e-0566723036582
Pubmed

A study on Notch signaling in human breast cancer.

DLL4 NOTCH4

5.46e-05667217822320
Pubmed

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.

KDM5A KDM5C

5.46e-05667221960634
Pubmed

FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.

FOXO6 FOXO4

5.46e-05667217974917
Pubmed

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins.

FOXO6 FOXO4

5.46e-05667221708191
Pubmed

Notch4 reveals a novel mechanism regulating Notch signal transduction.

DLL4 NOTCH4

5.46e-05667224667410
Pubmed

Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.

ATP1A1 ATP1A3

5.46e-05667210636900
Pubmed

Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.

ATP1A1 ATP1A3

7.63e-05767210837135
Pubmed

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis.

DLL4 NOTCH4

7.63e-05767218952909
Pubmed

Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland.

DSG1 ATP1A1

7.63e-05767216399075
Pubmed

Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis.

SLC44A4 NOTCH4

7.63e-05767224837172
Pubmed

Molecular genetics of Na,K-ATPase.

ATP1A1 ATP1A3

7.63e-0576722158121
Pubmed

POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters.

ATP1A1 ATP2B4

7.63e-05767222084111
Pubmed

Expression and distribution of Na, K-ATPase isoforms in the human uterus.

ATP1A1 ATP1A3

7.63e-05767220065300
Pubmed

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.

ATP1A1 ATP1A3

1.02e-04867219683723
Pubmed

Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.

ATP1A1 ATP1A3

1.02e-0486722885848
Pubmed

Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.

ATP1A1 ATP1A3

1.02e-04867223652595
Pubmed

ZBTB20 is essential for cochlear maturation and hearing in mice.

ATP1A1 ATP1A3 WNK4

1.04e-044767337279265
Pubmed

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

NFATC1 DLL4 NOTCH4

1.11e-044867328924218
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM5A KDM5C KDM5D

1.18e-044967334368113
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

DLL4 NOTCH4

1.30e-04967216245338
Pubmed

The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.

ATP1A1 ATP1A3

1.30e-04967215253893
Pubmed

Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle.

NFATC1 ATP2B4

1.30e-04967212660151
Pubmed

Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.

DLL4 NOTCH4

1.30e-04967211944948
Pubmed

Common variants at 5q22 associate with pediatric eosinophilic esophagitis.

SHROOM3 DSG1

1.30e-04967220208534
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

DLL4 NOTCH4

1.30e-04967210837027
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

DLL4 NOTCH4

1.63e-041067223665443
Pubmed

Maternal Cripto is required for proper uterine decidualization and peri-implantation uterine remodeling.

DLL4 NOTCH4

1.63e-041067233590845
Pubmed

Unique functions for Notch4 in murine embryonic lymphangiogenesis.

DLL4 NOTCH4

1.63e-041067234665379
Pubmed

USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex.

NFATC1 TAB2

1.63e-041067223825189
Pubmed

Accelerated coronary angiogenesis by vegfr1-knockout endocardial cells.

NFATC1 DLL4

1.63e-041067223894673
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM5A KDM5C KDM5D

1.86e-045767318022353
Pubmed

The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.

DLL4 ITGA2B

1.99e-041167234910918
Pubmed

Notch-Tnf signalling is required for development and homeostasis of arterial valves.

NFATC1 DLL4

1.99e-041167226491108
GeneFamilyAT-rich interaction domain containing

KDM5A KDM5C KDM5D

6.86e-0615463418
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5A KDM5C KDM5D

3.00e-0524463485
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

SBF1 DENND4B DENND4C

3.41e-0525463504
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A3

1.32e-0474621208
GeneFamilyPHD finger proteins

KDM5A KDM5C KDM5D

1.55e-039046388
GeneFamilyAnkyrin repeat domain containing

KANK4 PLA2G6 NOTCH4 PPP1R16A

3.29e-03242464403
GeneFamilyForkhead boxes

FOXO6 FOXO4

5.35e-0343462508
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD2 SVEP1

9.25e-03574621179
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NFATC1 DLL4 NOTCH4

8.34e-0616663MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NFATC1 DLL4 NOTCH4

8.34e-0616663M2207
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 QSOX1 FLNB DLL4 ATP2B4 NOTCH4

3.50e-07184676087666ba949b129c53d7ace40f9e543e3875a7de
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT15 QSOX1 FLNB DLL4 ATP2B4 NOTCH4

3.73e-071866765d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 QSOX1 FLNB GPIHBP1 DLL4 NOTCH4

3.73e-071866769c7924875f70420720149287c500b4dfa8d24673
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 SHROOM3 UPK1A RGL3 SLC44A4 WNK4

5.37e-07198676edf3e1c2be9df5690492b9c8fc25e7e48ed5c92c
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK ZP1 UPK1A CCDC187 CD83

5.17e-0616667567370c49d7aedcb4eca802095f06b30f6bbf8919
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK ZP1 UPK1A CCDC187 CD83

5.17e-061666757f4e5976ede6478636aa567d6fc2b56ff7295fb8
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

SHROOM3 RGL3 CCDC187 CDHR5 SLC44A4

5.80e-06170675d682178d11d67eb5a02d0c6b3967645e37bcc62a
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB RASGRP4 DLL4 WNK4 NOTCH4

5.80e-0617067555fe16d98ea284d05fb899888e4569c685644c7b
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

SHROOM3 RGL3 CCDC187 CDHR5 SLC44A4

5.97e-061716751af575809b3334bfaa019ff26c56e6cb03c82ee8
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UPK1A DLL4 CDHR5 SLC44A4 WNK4

7.87e-06181675c7a220891567c7539ad5a9ac9db375f0de08ea00
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 QSOX1 FLNB DLL4 ATP2B4

8.08e-06182675c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 QSOX1 FLNB DLL4 ATP2B4

8.08e-06182675d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCelldroplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT15 QSOX1 FLNB DLL4 NOTCH4

9.45e-06188675405efea75233ecf70f7d19b630230798d817b7f2
ToppCellfacs-MAT-Fat-18m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPIHBP1 DLL4 KANK4 CDHR5 NOTCH4

9.95e-0619067534e56c5e7ea6a8f227dbaefe73cbb8818d18b523
ToppCellfacs-MAT-Fat-18m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPIHBP1 DLL4 KANK4 CDHR5 NOTCH4

9.95e-0619067514cdb660ad3aabcf49572173e7628d8b99dcbe6f
ToppCellfacs-MAT-Fat-18m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPIHBP1 DLL4 KANK4 CDHR5 NOTCH4

9.95e-061906759aaa48f3aad813c87a45efdbb67d255c94f6e6a4
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

QSOX1 SHROOM3 FCGBP SLC44A4 WNK4

1.10e-0519467549cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

QSOX1 SHROOM3 FCGBP SLC44A4 WNK4

1.10e-05194675fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCell3'-Child09-12-SmallIntestine-Epithelial-goblet|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

QSOX1 SHROOM3 FCGBP SLC44A4 WNK4

1.16e-05196675c2d17630f7bfc9e727de55e093c17fddac61b61f
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

QSOX1 FCGBP DLL4 SLC44A4 WNK4

1.16e-05196675847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell3'-Child09-12-SmallIntestine-Epithelial-goblet-Goblet_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

QSOX1 SHROOM3 FCGBP SLC44A4 WNK4

1.16e-0519667554c30023d04e7265373647f56fc93885804938b0
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHROOM3 UPK1A RGL3 SLC44A4 WNK4

1.21e-05198675ad9fb53cd216af9bc9998d6b3bd0255b45e0dbfb
ToppCelldistal-Endothelial-Artery-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNB GPIHBP1 DLL4 ATP1A1 NOTCH4

1.24e-051996753788f3218356aaaa10684e48d63757037f8a3a3c
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tmem163_Arhgap25|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NWD2 INF2 CD83 SLC44A4

2.93e-05117674e1a14b8413a6f4b194217a90eb2c5f95ab14522e
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Gkn1_Pcdh19|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

INF2 ADAMTS13 CD83 SLC44A4

6.60e-05144674e8caeb6485f4c8f9a3384570dc69024c2bcc9ab0
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF224 FRAS1 DLL4 INF2

9.22e-05157674ffb8dd381e6b9adc5283fb49586e8bd63773c8d6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF224 FRAS1 DLL4 INF2

9.22e-05157674c488ab1d6c6c7e5c2f4426805d1366b44711a031
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC7B CD83 ATP1A3 HERC4

9.22e-051576740ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZP1 ICAM3 C10orf95 FOXO4

9.22e-05157674d12f343454202da86a06d0369f8ffe5662cd091b
ToppCellfacs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC7B CD83 ATP1A3 HERC4

9.22e-05157674fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RNF224 FRAS1 SHROOM3 FRMPD1

9.68e-0515967450d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BLK UPK1A HES3 CD83

1.17e-041676743c3e1c31aacca48099693aea2efdfa22fc0e4af4
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPIHBP1 TTC7B SBF1 ADAMTS13

1.17e-04167674528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPIHBP1 TTC7B SBF1 ADAMTS13

1.17e-04167674a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BLK UPK1A HES3 CD83

1.17e-0416767477a4d7ce44847c76074d4f5340d61b398fe43e6c
ToppCellfacs-GAT-Fat-18m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP UPK1A CDHR5 SLC44A4

1.20e-04168674d6c8056b7d6b937bb91e6b33beeb1075dce1685c
ToppCellfacs-GAT-Fat-18m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP UPK1A CDHR5 SLC44A4

1.20e-041686747102c52bf1b2ba67bb3700932181a2e0a6627711
ToppCellfacs-GAT-Fat-18m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP UPK1A CDHR5 SLC44A4

1.20e-0416867468a2f9fd53b54023241acd1620cf24226f639c1b
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BLK ATP1A3 KLHL33 NOTCH4

1.20e-04168674c34dd4a9c54d8e9c8f118e6a3816548890cb0746
ToppCellcontrol-Myeloid-Eosinophils|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FLNB TTC7B PLA2G6 ITGA2B

1.28e-0417167482f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCellClub-club-3|World / Class top

SYT15 QSOX1 FCGBP SLC44A4

1.31e-0417267434fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCellsevere_influenza-B_memory|World / disease group, cell group and cell class (v2)

BLK COL4A4 RGL3 CD83

1.31e-041726740ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

QSOX1 SHROOM3 HERC4 WNK4

1.31e-041726746ece9bb9f31685c918ca4cb7b82cf6ad1cad48af
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 UPK1A INF2 ATP1A3

1.34e-041736743c51e7bda1835c25915e50c801b0d643979971a3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 UPK1A INF2 ATP1A3

1.34e-04173674a042f78a4c69fcc6b5ca76e9bf01e34cee54c81c
ToppCellmild_COVID-19_(asymptomatic)-B_memory|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

BLK COL4A4 UPK1A CD83

1.34e-041736749082ad77b44f65b72094df6e502cce81b62fe81a
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK UPK1A CD83 KLHL33

1.37e-0417467428ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCellControl-CD4+_T_activated|Control / Disease group and Cell class

FLT3LG NFATC1 HYAL3 CD83

1.37e-041746742b683e81b315ad22555314433aed5681feb48da8
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UPK1A CCDC187 SLC44A4 WNK4

1.37e-04174674ca067e8ec55bbc3deafc09f08bc13af08364d165
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CCDC187 C10orf95 SLC44A4 LMNTD1

1.37e-04174674b8d1c556290d188f56aeefc17f03119686945fe7
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CCDC187 C10orf95 SLC44A4 LMNTD1

1.37e-0417467400cf27bc23af1472a507be31fba6245a8fdd901b
ToppCellfacs-Spleen-nan-24m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK FRAS1 UPK1A CD83

1.37e-04174674a0641908ab6feaca5cd07142d7429983a2f68668
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5+_CCL22+_mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BLK NFATC1 ICAM3 CD83

1.40e-04175674fa53ea81ad943a2cd266114829135cbcbcf2f634
ToppCellfacs-BAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK GPIHBP1 UPK1A CD83

1.40e-0417567446d6e319f8ca46592f23257800bcb6d228fffbbe
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A4 FRAS1 KDM5A KANK4

1.40e-041756749a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CCDC187 C10orf95 SLC44A4 LMNTD1

1.40e-04175674b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TTC7B HYAL3 FOXO4 ITGA2B

1.40e-04175674ba1befc4e5f0167452f9ceace39377d16136dfa9
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CCDC187 C10orf95 SLC44A4 LMNTD1

1.40e-04175674c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A4 FRAS1 KDM5A KANK4

1.43e-04176674458720776b0151cd55acc352d509599cb62f0ca8
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK FRAS1 UPK1A CD83

1.43e-04176674741fdacb33d49b030a797a6099fdea0949a22e75
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK FRAS1 UPK1A CD83

1.49e-041786740265c0bc005c05fd5906a88c1eafd17891e952f1
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK NFATC1 UPK1A CD83

1.49e-041786745a4f97d19265577cfdb3e53f9dc3a9a02cfcffa9
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

RASGRP4 CSMD2 SVEP1 NOTCH4

1.53e-04179674cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK UPK1A HYAL3 CD83

1.53e-0417967469c74b2ff43b43653005807654953daf21f932ec
ToppCell-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

BLK FLT3LG ICAM3 SVEP1

1.53e-04179674e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A4 FRAS1 SHROOM3 RGL3

1.53e-0417967404ce3673e46606f63d9c87bcba3a64c96817d812
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPIHBP1 TFAP2E DLL4 HES3

1.53e-04179674ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPIHBP1 TFAP2E DLL4 HES3

1.53e-04179674d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCellmild_COVID-19-NK_CD56bright|mild_COVID-19 / disease group, cell group and cell class (v2)

FLNB FRAS1 PLA2G6 CSMD2

1.56e-04180674d8b418edd807a51c0b5f4018b8b478dcc65892a7
ToppCelldroplet-Lung-nan-21m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK FRAS1 UPK1A CD83

1.56e-04180674b673d11d764e275883fc5edbad97137a6549df6a
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A4 FRAS1 SHROOM3 RGL3

1.59e-04181674b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FLNB GPIHBP1 DLL4 NOTCH4

1.59e-041816749cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK UPK1A HYAL3 CD83

1.59e-04181674d90faa6115b408c9fbca61fc90ff951e070754ba
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 GPIHBP1 DLL4 NOTCH4

1.63e-04182674840427d1c23d60482c943ff006b14007ed44d247
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYT15 FLNB DLL4 NOTCH4

1.66e-041836743427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

QSOX1 FCGBP DLL4 CD83

1.66e-04183674ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

QSOX1 FCGBP DLL4 CD83

1.66e-04183674c52b84034503d931f7b87312d2ff86daff14152d
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT15 GPIHBP1 DLL4 NOTCH4

1.70e-04184674fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCellwk_20-22-Hematologic_Lymphocytic-B-CD5+_CCL22+_mature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

BLK NFATC1 ICAM3 CD83

1.70e-041846745bb775253a10a14360b06a46aba46d162a9bd1f8
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A4 FRAS1 SHROOM3 RGL3

1.70e-0418467442ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHROOM3 FCGBP SLC44A4 WNK4

1.70e-04184674886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 GPIHBP1 DLL4 NOTCH4

1.70e-04184674ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHROOM3 FCGBP SLC44A4 WNK4

1.70e-04184674936b39377eebea3961d702532779f6cd27953be7
ToppCellSerous|World / shred by cell class for bronchial biopsy

QSOX1 FCGBP CD83 WNK4

1.70e-0418467409d0d1525c11dd326efd942684c03f79d992cf3b
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT15 GPIHBP1 DLL4 NOTCH4

1.70e-041846741d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT15 GPIHBP1 DLL4 NOTCH4

1.70e-0418467476caad53d55fff5acca27bf190a6de7b27437d9f
ToppCellcontrol-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FLNB TTC7B PLA2G6 ITGA2B

1.70e-04184674fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 GPIHBP1 DLL4 NOTCH4

1.70e-041846741fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 GPIHBP1 DLL4 NOTCH4

1.70e-041846742467207aaea307873ab286f89cfc7668a227a694
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

GPIHBP1 TTC7B DLL4 NOTCH4

1.73e-04185674ad52970e88e8947ef256095bd4b40229b912d58a
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BLK FRAS1 UPK1A CD83

1.73e-041856745fd4a3776259c96cf2dcb87f050af8226acbbda9
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT15 QSOX1 DLL4 ATP2B4

1.73e-04185674eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A4 FRAS1 SHROOM3 RGL3

1.73e-04185674c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BLK FRAS1 UPK1A CD83

1.73e-041856744c55fa96877ab9a00fcbec3fb70fd2208d222527
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A4 GPIHBP1 ATP2B4 NOTCH4

1.77e-041866742cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A4 FRAS1 SHROOM3 RGL3

1.77e-041866744e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A4 FRAS1 SHROOM3 RGL3

1.77e-041866743aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A4 GPIHBP1 ATP2B4 NOTCH4

1.77e-0418667490d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYT15 FLNB DLL4 NOTCH4

1.81e-0418767412129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A4 FRAS1 SHROOM3 RGL3

1.81e-0418767458d48128547ee3513d0bf7f78e61b76b1c472ca9
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5A KDM5C KDM5D

4.07e-084653DOID:0060809 (implicated_via_orthology)
Diseasedystonia 12 (is_implicated_in)

PLA2G6 ATP1A3

4.78e-062652DOID:0090056 (is_implicated_in)
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5A KDM5C KDM5D

5.60e-0616653DOID:0050888 (implicated_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

KDM5A KDM5C ITGA2B KDM5D

2.32e-0575654DOID:1059 (implicated_via_orthology)
Diseasehemangioblastoma (is_marker_for)

DLL4 NOTCH4

2.86e-054652DOID:5241 (is_marker_for)
Diseasesystemic lupus erythematosus

BLK SHROOM3 NFATC1 ICAM3 CDHR5 CD83 SLC44A4 LMNTD1 NOTCH4

6.16e-05799659MONDO_0007915
Diseasehypertensive nephropathy

COL4A4 INF2

7.13e-056652C0848548
Diseasealcohol use disorder (implicated_via_orthology)

KDM5A KDM5C ATP1A1 KDM5D ATP1A3

7.17e-05195655DOID:1574 (implicated_via_orthology)
Diseasecups of coffee per day measurement

ATP1A1 ATP1A3 SLC44A4

9.51e-0540653EFO_0006782
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A3

9.96e-057652DOID:0060178 (implicated_via_orthology)
Diseasehemangiopericytoma (is_marker_for)

DLL4 NOTCH4

1.70e-049652DOID:264 (is_marker_for)
Diseaserheumatoid arthritis, systemic lupus erythematosus

BLK ICAM3

2.13e-0410652EFO_0000685, MONDO_0007915
Diseaseabdominal adipose tissue measurement

ATP1A1 ATP1A3 ATP2B4

2.21e-0453653EFO_0803316
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A3

3.11e-0412652DOID:863 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

KDM5A KDM5C SCAMP3 KDM5D

3.59e-04152654DOID:0060041 (implicated_via_orthology)
Diseasesystemic scleroderma

BLK CDHR5 NOTCH4

8.86e-0485653EFO_0000717
DiseaseRenal glomerular disease

COL4A4 INF2

1.17e-0323652C0268731
DiseaseGlomerulopathy Assessment

COL4A4 INF2

1.17e-0323652C4521256
Diseasecongenital heart disease (is_implicated_in)

NFATC1 TAB2

1.28e-0324652DOID:1682 (is_implicated_in)
DiseaseS-7-hydroxywarfarin measurement

SHROOM3 CSMD2 HERC4

1.86e-03110653EFO_0803329
DiseaseOvarian Mucinous Adenocarcinoma

ALPK1 WNK4

2.13e-0331652C1335167

Protein segments in the cluster

PeptideGeneStartEntry
PEKRSPFPQQPWSAV

CCDC187

521

A0A096LP49
PFPQQPWSAVATQPC

CCDC187

526

A0A096LP49
DQPCQPPPWVQLQLS

LINC00588

81

Q9Y4M8
PRFSATVPPCWVEVQ

BIRC6

1036

Q9NR09
RFFWQPSPPTCIAPC

CSMD2

1431

Q7Z408
QDQSIPPCPQTWRSL

COL4A4

1581

P53420
RCEFPVGLPPSFPWV

DLL4

516

Q9NR61
NVVPADLRPPWFLPC

CDHR5

226

Q9HBB8
NFVINRRPWLPECTP

ATP2B4

386

P23634
PQPCPARWEVSEPSS

ADAMTS13

801

Q76LX8
LPCSSFTPNWPVQNP

ALPK1

816

Q96QP1
AQPQPPQAAWAAPRA

TFAP2E

91

Q6VUC0
PDQPWVFQCNPLEPD

NWD2

811

Q9ULI1
PQFPKVQWPPRELCS

QSOX1

496

O00391
VDLPCTAPWDPQVPY

CD83

31

Q01151
LNVWRPAPALPAPCF

KLHL33

346

A6NCF5
IPCTVQPTQPWVDPG

FRAS1

3611

Q86XX4
ACVEALPAVPWVPQP

MAGEL2

826

Q9UJ55
CNVPPWQSSRVQDPT

GPIHBP1

136

Q8IV16
TPPPTTPEWIKFCRQ

ATP1A1

81

P05023
PPECPVFEPSWAEFQ

KDM5D

11

Q9BY66
LQCQPDSSTLPPPWS

FLT3LG

156

P49771
PVNACPPGFRPWVTE

FLNB

1716

O75369
CTWPLPRPEIANQPS

FOXO4

31

P98177
LFRPCTPAVWAPAPA

HES3

116

Q5TGS1
PPDDFRCPNPTKQIW

HERC4

386

Q5GLZ8
FAPQSRPRSCTWPLP

FOXO6

16

A8MYZ6
SLPPSPFNAPLVVEW

RASGRP4

436

Q8TDF6
PYASPQTSPWQSPCV

NFATC1

196

O95644
EIPPTVFPNRSPWCQ

LMNTD1

321

Q8N9Z9
EPPQVWTGPPRVAQT

RGL3

206

Q3MIN7
QSWPSCLPPPADLEI

CCDC182

36

A6NF36
LDPSWPPQSTEPVCL

DSG1

771

Q02413
IRPPKDWQPPFACEV

KDM5A

51

P29375
PQCPQPLEGAWPVTL

INF2

1091

Q27J81
PPWQPVGQNFTLRCQ

ICAM3

126

P32942
PSGWQLCPERNPPTF

SBF1

51

O95248
PAPCVPRFAALPWAT

GIG44

86

P09565
PWRTETFCPMECPPN

FCGBP

1521

Q9Y6R7
PRDSPEWVCFNPEPS

FRMPD1

1241

Q5SYB0
LTLPCVRPAPQNPWA

BLK

216

P51451
QPLPQVPERPFSVLW

HYAL3

21

O43820
PFQWQCPYIPLCPLS

DENND4C

441

Q5VZ89
TPPPTTPEWVKFCRQ

ATP1A3

71

P13637
PDPNSCPPLYVLWRV

DENND4B

1356

O75064
WISQGRDPIFQPPSP

FPGS

526

Q05932
PPLQNWSPVVPREAS

KANK4

86

Q5T7N3
PALGRCFPWTNVTPP

SLC44A4

176

Q53GD3
RQNNWPPLPSFCPVQ

SCAMP3

131

O14828
EVQLQPPEVWSPDPC

TRIM41

391

Q8WV44
PFVVPPTLQGRDWVP

SYT15

76

Q9BQS2
QVYQPSQPGPWTTCP

TAB2

246

Q9NYJ8
SLFWEVDPPPIPVNC

SSMEM1

6

Q8WWF3
AQEAIVWQQPPPTSP

PPP1R16A

366

Q96I34
DTPAPEQRWIPCPQC

RNF224

56

P0DH78
VPPPSWSQQCPSSLE

SHROOM3

356

Q8TF72
VPVTCVDVFRPSNPW

PLA2G6

701

O60733
QCFPQPPVNPLKVDW

ITGA2B

856

P08514
EPPVIDWCRSPPPVQ

SVEP1

646

Q4LDE5
PANQLPWPVLCSPVA

NOTCH4

1441

Q99466
PVQLPSPACTSTQWP

TRIOBP

1651

Q9H2D6
TWPPLCCYPQSRPTA

C10orf95

71

Q9H7T3
FQQPQWPILSDGCPF

ZP1

466

P60852
RAATPEVVFPWPPLC

UPK1A

176

O00322
SQAVLLPSVCPVPWP

FP248

161

Q71RG6
QSYWNPLEDPPCQSP

TTC7B

276

Q86TV6
IPGQQPIPTTWPDCL

STRCP1

1121

A6NGW2
PKPQPVNPELTSWCI

TRIM64C

261

A6NLI5
EFPVPLSQCPWSSLP

WNK4

871

Q96J92
PPECPVFEPSWAEFR

KDM5C

11

P41229