Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfructose-bisphosphate aldolase activity

ALDOA ALDOB ALDOC

2.12e-0731203GO:0004332
GeneOntologyMolecularFunctionaldehyde-lyase activity

ALDOA ALDOB ALDOC

3.37e-05111203GO:0016832
GeneOntologyMolecularFunctionL-leucine-2-oxoglutarate transaminase activity

BCAT1 BCAT2

3.58e-0521202GO:0052654
GeneOntologyMolecularFunctionL-valine-2-oxoglutarate transaminase activity

BCAT1 BCAT2

3.58e-0521202GO:0052655
GeneOntologyMolecularFunctionL-isoleucine-2-oxoglutarate transaminase activity

BCAT1 BCAT2

3.58e-0521202GO:0052656
GeneOntologyMolecularFunctionbranched-chain-amino-acid transaminase activity

BCAT1 BCAT2

3.58e-0521202GO:0004084
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

SRCAP ABHD14B MCM3AP BRD1

3.34e-04551204GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

SRCAP ABHD14B MCM3AP BRD1

4.67e-04601204GO:0034212
GeneOntologyMolecularFunctionfructose binding

ALDOA ALDOB

5.29e-0461202GO:0070061
GeneOntologyMolecularFunctioncell adhesion molecule binding

ANK3 ITGAM CNTN6 KIRREL3 ARVCF ICAM5 CNTN5 KIRREL1 MACF1 ROBO3 ALDOA

9.78e-0459912011GO:0050839
GeneOntologyMolecularFunctionN-acetyltransferase activity

SRCAP ABHD14B MCM3AP BRD1

1.26e-03781204GO:0008080
GeneOntologyBiologicalProcessfructose 1,6-bisphosphate metabolic process

ALDOA ALDOB ALDOC

1.46e-0591173GO:0030388
GeneOntologyBiologicalProcessL-leucine biosynthetic process

BCAT1 BCAT2

3.19e-0521172GO:0009098
GeneOntologyBiologicalProcesspyruvate family amino acid biosynthetic process

BCAT1 BCAT2

3.19e-0521172GO:0009079
GeneOntologyBiologicalProcessfructose metabolic process

ALDOA ALDOB ALDOC

9.44e-05161173GO:0006000
GeneOntologyBiologicalProcessL-valine biosynthetic process

BCAT1 BCAT2

9.54e-0531172GO:0009099
DomainFBA_I

ALDOA ALDOB ALDOC

2.40e-0731173IPR000741
DomainGlycolytic

ALDOA ALDOB ALDOC

2.40e-0731173PF00274
DomainAldolase_I_AS

ALDOA ALDOB ALDOC

2.40e-0731173IPR029768
DomainALDOLASE_CLASS_I

ALDOA ALDOB ALDOC

2.40e-0731173PS00158
DomainIg_I-set

PDGFRB CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 KIRREL1 FGFR4 ROBO3

3.10e-061901179IPR013098
DomainI-set

PDGFRB CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 KIRREL1 FGFR4 ROBO3

3.10e-061901179PF07679
DomainIGc2

PDGFRB CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 KIRREL1 FGFR4 ROBO3

1.72e-052351179SM00408
DomainIg_sub2

PDGFRB CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 KIRREL1 FGFR4 ROBO3

1.72e-052351179IPR003598
DomainAA_TRANSFER_CLASS_4

BCAT1 BCAT2

3.89e-0521172PS00770
DomainAminotrans_IV_CS

BCAT1 BCAT2

3.89e-0521172IPR018300
DomainBCAT_family

BCAT1 BCAT2

3.89e-0521172IPR033939
DomainAminotran_4

BCAT1 BCAT2

3.89e-0521172PF01063
DomainAminotrans_IV

BCAT1 BCAT2

3.89e-0521172IPR001544
DomainB_amino_transII

BCAT1 BCAT2

3.89e-0521172IPR005786
DomainIg-like_fold

FLNC EPM2A PDGFRB TRIM3 CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 BTN1A1 PKHD1 KIRREL1 FGFR4 ROBO3

1.35e-0470611714IPR013783
Domain-

FLNC EPM2A PDGFRB TRIM3 CNTN6 KIRREL3 ICAM5 CNTN5 BTN1A1 PKHD1 KIRREL1 FGFR4 ROBO3

2.64e-04663117132.60.40.10
DomainIG

PDGFRB CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 BTN1A1 KIRREL1 FGFR4 ROBO3

3.18e-0442111710SM00409
DomainIg_sub

PDGFRB CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 BTN1A1 KIRREL1 FGFR4 ROBO3

3.18e-0442111710IPR003599
DomainIG_LIKE

PDGFRB CNTN6 KIRREL3 HMCN2 ICAM5 CNTN5 BTN1A1 KIRREL1 FGFR4 ROBO3

1.04e-0349111710PS50835
Pubmed

Mode of interactions of human aldolase isozymes with cytoskeletons.

ALDOA ALDOB ALDOC

4.11e-08312139244396
Pubmed

Aldolase positively regulates of the canonical Wnt signaling pathway.

ALDOA ALDOB ALDOC

4.11e-083121324993527
Pubmed

Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments.

ALDOA ALDOB ALDOC

4.11e-08312136696436
Pubmed

Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.

ALDOA ALDOB ALDOC

1.64e-074121311399750
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

DOCK3 EPM2A NAGK ANK3 VWA7 HMCN2 MAP1S MACF1 ALDOA SON

5.85e-073611211026167880
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNC NAGK ANK3 COL5A3 XPNPEP1 SRCAP HNRNPF AP1G1 MACF1 ALDOA ALDOC PCCB MTCH2 HYDIN

8.97e-078071211430575818
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLNC EVC2 NAGK ANK3 USP25 BCAT1 PELP1 AP1G1 MCM3AP MACF1 BRD1 SON

1.13e-065911211215231748
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNC ANK3 KIAA1549 DHX57 HNRNPF TRIM3 PITPNM1 MAP1S AP1G1 ARVCF ICAM5 MACF1 ARHGEF2 CORO7 ALDOA ALDOC ATP2B3 MTCH2

2.35e-0614311211837142655
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 DPH2 FLNC PPRC1 THAP8 TSC2 SRCAP KIAA2013 SLC38A10 MAP1S ARVCF MCM3AP ZFYVE26 ARHGEF2 MFSD5

7.20e-0611051211535748872
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 NAGK ANK3 PDGFRB PPRC1 USP25 TSC2 BATF2 HNRNPF SH2B1 MAP1S ATRNL1 MACF1 ALDOA FUT8 PCCB

1.03e-0512851211635914814
Pubmed

Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm).

BCAT1 BCAT2

1.20e-05212129165094
Pubmed

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease.

BCAT1 BCAT2

1.20e-052121214755340
Pubmed

Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A.

ALDOA ALDOC

1.20e-05212123009179
Pubmed

Branched-chain aminotransferase deficiency in Chinese hamster cells complemented by two independent genes on human chromosomes 12 and 19.

BCAT1 BCAT2

1.20e-05212126933702
Pubmed

S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation.

BCAT1 BCAT2

1.20e-052121219119849
Pubmed

Differential redox potential between the human cytosolic and mitochondrial branched-chain aminotransferase.

BCAT1 BCAT2

1.20e-052121222107788
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

1.20e-052121211687802
Pubmed

Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.

BCAT1 BCAT2

1.20e-052121216141215
Pubmed

Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans.

ALDOA ALDOB

1.20e-052121225637246
Pubmed

Branched-chain amino acid metabolism in cancer.

BCAT1 BCAT2

1.20e-052121229211698
Pubmed

Bcat1 is controlled by Tsc2/mTORC1 pathway at expression levels and its deficiency together with Bcat2 inactivation suppresses the growth of a Tsc2-/- tumor cell line.

BCAT1 TSC2

1.20e-052121236965015
Pubmed

Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle.

BCAT1 BCAT2

1.20e-052121217767905
Pubmed

Expression of mKirre in the developing sensory pathways: its close apposition to nephrin-expressing cells.

KIRREL3 KIRREL1

1.20e-052121218022324
Pubmed

Distribution of the branched chain aminotransferase proteins in the human brain and their role in glutamate regulation.

BCAT1 BCAT2

1.20e-052121223043456
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

1.20e-052121234910522
Pubmed

Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover.

BCAT1 BCAT2

1.20e-052121226351290
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

CNTN6 KIRREL3 ICAM5 CNTN5 KIRREL1 ROBO3

2.30e-05162121625826454
Pubmed

Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching.

ALDOA ALDOB ALDOC

3.23e-0518121328049690
Pubmed

The role of obesity-related genetic loci in insulin sensitivity.

SH2B1 MTCH2

3.59e-053121222443470
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

3.59e-053121230801007
Pubmed

Laforin, the most common protein mutated in Lafora disease, regulates autophagy.

EPM2A TSC2

3.59e-053121220453062
Pubmed

Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.

FLNC ANK3

3.59e-053121221223964
Pubmed

Inhibition of RAC1-GEF DOCK3 by miR-512-3p contributes to suppression of metastasis in non-small cell lung cancer.

DOCK3 ARHGEF2

3.59e-053121225687035
Pubmed

Phospholipase D2 directly interacts with aldolase via Its PH domain.

ALDOA ALDOC

3.59e-053121211876650
Pubmed

Oral leucine supplementation is sensed by the brain but neither reduces food intake nor induces an anorectic pattern of gene expression in the hypothalamus.

BCAT1 BCAT2

3.59e-053121224349566
Pubmed

Comparative analysis of Neph gene expression in mouse and chicken development.

KIRREL3 KIRREL1

3.59e-053121222205279
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK3 ZNF407 SH2B1 RSPRY1 KIAA2013 CEP68 PTCD1 ATRNL1 MACF1

5.97e-05493121915368895
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

RBM42 TSC2 SRCAP TRIM3 MAP1S MACF1 ALDOC

6.01e-05281121724163370
Pubmed

A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis.

KIRREL3 KIRREL1

7.17e-054121220233749
Pubmed

Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis.

KIRREL3 KIRREL1

7.17e-054121216874800
Pubmed

Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments.

ITGAM AP1G1

7.17e-054121220299515
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

STRC STRCP1

7.17e-054121218849963
Pubmed

Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system.

CNTN6 CNTN5

7.17e-05412121838307
Pubmed

Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism.

BCAT1 BCAT2

7.17e-054121228219950
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

FLNC PDGFRB ZNF407 HNRNPF RSPRY1 ZFPL1 ZNF668 PELP1 SEC61B KIRREL1 ALDOA FUT8 MTCH2 YIPF3

7.88e-0512031211429180619
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

BCAT1 ZNF407 TACC2 MBNL2 CBX7 KIRREL1 ARHGEF2 BRD1 FUT8

1.13e-04536121915840001
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TSC2 KIAA2013 ZFPL1 AP1G1 KIRREL1 ARHGEF2 CORO7 HEATR5B FUT8 MTCH2 HSPA14 YIPF3

1.14e-049421211231073040
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

BCAT1 ZNF407 TACC2 MBNL2 CBX7 KIRREL1 ARHGEF2 BRD1 FUT8

1.16e-04538121910512203
Pubmed

Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.

CNTN6 CNTN5

1.19e-045121227539848
Pubmed

Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi.

AP1G1 CORO7

1.19e-045121216905771
Pubmed

Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations.

ALDOA ALDOC

1.19e-04512123674018
Pubmed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.

STRC STRCP1

1.19e-045121224920589
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

TSC2 TACC2 ABHD14B HNRNPF CRIP2 MAP1S PELP1 AP1G1 MACF1 ARHGEF2 ALDOA MTCH2 HSPA14 MOCS2 SON

1.22e-0414151211528515276
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

FLNC ANK3 HNRNPF CRIP2 PITPNM1 SEC61B ALDOA ALDOC MTCH2

1.52e-04558121935063084
Pubmed

Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.

SH2B1 MTCH2

1.78e-046121219910938
Pubmed

Role of Neph2 in pontine nuclei formation in the developing hindbrain.

KIRREL3 KIRREL1

1.78e-046121221241806
Pubmed

PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis.

PDGFRB SH2B1

1.78e-046121210644978
Pubmed

Ras and relatives--job sharing and networking keep an old family together.

RAPGEF3 ARHGEF2

1.78e-046121212384139
Pubmed

Two additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinase.

PDGFRB FGFR4

1.78e-04612121720539
Pubmed

The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins.

FLNC USP25

1.78e-046121216501887
Pubmed

Defining the membrane proteome of NK cells.

PDGFRB HNRNPF KIAA2013 PELP1 AP1G1 CORO7 HEATR5B FUT7 ALDOA FUT8 MTCH2 MFSD5 HSPA14

2.22e-0411681211319946888
Pubmed

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics.

KIRREL3 CNTN5

2.49e-047121227565351
Pubmed

A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.

KIRREL3 KIRREL1

2.49e-047121227430022
Pubmed

Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts.

PDGFRB LGR6

2.49e-047121235302583
Pubmed

Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.

SH2B1 MTCH2

2.49e-047121220386550
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

TCAF2 FLNC HNRNPF MMRN2 MACF1 CORO7 MAP4K2

2.76e-04360121733111431
Pubmed

PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts.

PDGFRB BCAT1 BCAT2

2.93e-0437121315735755
Pubmed

Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles.

KIRREL3 KIRREL1

3.32e-048121218752272
Pubmed

Characterization of murine BCAT genes: Bcat1, a c-Myc target, and its homolog, Bcat2.

BCAT1 BCAT2

3.32e-04812129657861
Pubmed

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

STRC STRCP1

3.32e-048121221165971
Pubmed

NEPH1 defines a novel family of podocin interacting proteins.

KIRREL3 KIRREL1

3.32e-048121212424224
Pubmed

MC4R variant is associated with BMI but not response to resistance training in young females.

SH2B1 MTCH2

3.32e-048121220725061
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

DHX57 TACC2 HNRNPF ZNF668 PELP1 MACF1 UTP3 ARHGEF2 HSPA14 SON

3.32e-047591211035915203
Pubmed

Ellis-van Creveld Syndrome

EVC2 DYNC2LI1

4.25e-049121237903214
Pubmed

Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project.

NUGGC ANK3

4.25e-049121220877300
Pubmed

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden.

SH2B1 MTCH2

4.25e-049121219164386
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PPRC1 CEP68 ATRNL1 MCM3AP

5.08e-0410512149628581
Pubmed

Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa?

SH2B1 MTCH2

5.30e-0410121219746409
Pubmed

Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference.

SH2B1 MTCH2

5.30e-0410121219692490
Pubmed

Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation.

USP25 ACSBG2 PCCB

5.59e-0446121331560077
Pubmed

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

BCAT1 COL5A3 HNRNPF RSPRY1 PELP1 ALDOA

5.70e-04292121612819125
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

ANK3 PPRC1 TACC2 XPNPEP1 HNRNPF ATRNL1 HSPA14

6.44e-04415121716385451
Pubmed

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

SH2B1 MTCH2

6.47e-0411121219079261
Pubmed

Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites.

PDGFRB SH2B1

6.47e-0411121231585087
Pubmed

Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.

STRC STRCP1

6.47e-0411121231448880
Pubmed

The aftiphilin/p200/gamma-synergin complex.

AP1G1 HEATR5B

6.47e-0411121215758025
Pubmed

Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.

STRC STRCP1

6.47e-0411121231776257
Pubmed

USP25-PKM2-glycolysis axis contributes to ischemia reperfusion-induced acute kidney injury by promoting M1-like macrophage polarization and proinflammatory response.

USP25 ALDOA

6.47e-0411121236894047
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

FLNC ANK3 XPNPEP1 AP1G1 SEC61B ALDOC

7.04e-04304121632235678
Pubmed

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.

ALDOA ALDOC PCCB MTCH2 SON

7.41e-04203121516916647
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

FLNC ANK3 ABHD14B HNRNPF PELP1 PTCD1 MACF1 ALDOA ALDOC MTCH2

7.55e-048441211025963833
Pubmed

A role for Nr-CAM in the patterning of binocular visual pathways.

CNTN6 CNTN5

7.74e-0412121216701205
Pubmed

Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.

KIRREL3 CNTN5

7.74e-0412121224411736
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNC DHX57 SRCAP ABHD14B HNRNPF AP1G1 ARVCF MCM3AP MACF1 ARHGEF2 CORO7 ALDOA SON

8.84e-0413531211329467282
Pubmed

A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles.

PDGFRB TSC2

9.13e-0413121219357198
Pubmed

Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression.

KIRREL3 KIRREL1

9.13e-0413121223637329
Pubmed

Pioneering axons regulate neuronal polarization in the developing cerebral cortex.

CNTN6 CNTN5

9.13e-0413121224559674
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SLC39A1 KIAA1549 TSC2 CRIP2 KIAA2013 THBS3 SEC61B KIRREL1 FGFR4 FUT8 MTCH2 MFSD5

1.00e-0312011211235696571
Pubmed

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

MAP1S MACF1 ARHGEF2

1.05e-0357121329089450
Pubmed

Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.

PDGFRB FGFR4

1.06e-0314121211350938
Cytoband16p11.2

ZNF843 SRCAP ITGAM SH2B1 ZNF668 ALDOA

1.24e-05191121616p11.2
CytobandEnsembl 112 genes in cytogenetic band chr16p11

ZNF843 SRCAP ITGAM SH2B1 ZNF668 ALDOA

1.00e-042781216chr16p11
Cytoband11q13

ZFPL1 PITPNM1 MAP4K2 NPAS4

2.79e-04118121411q13
Cytoband19q13.12

RBM42 THAP8 IGFLR1

9.33e-0472121319q13.12
Cytoband3p21.2

DOCK3 ABHD14B

1.14e-031912123p21.2
Cytoband10q26

TACC2 ATRNL1

1.68e-0323121210q26
Cytoband15q15.3

STRC STRCP1

1.99e-0325121215q15.3
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PDGFRB CNTN6 KIRREL3 HMCN2 CNTN5 KIRREL1 FGFR4 ROBO3

4.59e-07161788593
GeneFamilyImmunoglobulin like domain containing

PDGFRB KIRREL3 HMCN2 ICAM5 CNTN5 KIRREL1 ROBO3

1.97e-05193787594
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

KIRREL3 BTN1A1 KIRREL1

6.80e-0440783592
GeneFamilyFucosyltransferases|Blood group antigens

FUT7 FUT8

1.39e-0313782434
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANK3 BCAT1 CNTN6 ICAM5 PKHD1 RNF39 SON

1.15e-0619712173d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK3 CNTN6 PKHD1 LGR6 ATP2B3 HYDIN

5.42e-061621216bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DHX57 DBNDD1 MCM3AP KIRREL1 LGR6 HSF4

6.46e-061671216dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL5A3 AGMO KIRREL1 FGFR4 LGR6 FUT8

7.15e-061701216ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA4 KIAA1549 PERM1 COL5A3 SYT8 HYDIN

1.09e-0518312166f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 RGS14 NLRP10 DBNDD1 ICAM5 CNTN5

1.09e-051831216bf7f1cb55ed55981b8b355d5774055c96e658ff2
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 RGS14 NLRP10 DBNDD1 ICAM5 CNTN5

1.09e-0518312169533db4db2c6ae78d7ca1682cf4efed12183396f
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 PDGFRB THBS3 ARVCF DYNC2LI1 KIRREL1

1.16e-051851216f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 PDGFRB THBS3 ARVCF DYNC2LI1 KIRREL1

1.16e-05185121640e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 PDGFRB THBS3 ARVCF DYNC2LI1 KIRREL1

1.16e-0518512165f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RGS14 ICAM5 STRC FUT7 ALDOB

1.26e-051101215ff196c71aa2a21cdd812958bd163fa6b91bd2352
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RGS14 ICAM5 STRC FUT7 ALDOB

1.26e-051101215438bf761ab0a25e3dc9244c23ae2c2d68a169c7f
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RGS14 ICAM5 STRC FUT7 ALDOB

1.26e-05110121546635a130453c2fa304f0e09561b2a267c9ceb31
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RGS14 ICAM5 STRC FUT7 ALDOB

1.26e-0511012153639fb5fc02eca509cb220295bc3e6064c23baab
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA4 ASIC3 CEP68 UBAP1L NIPA1 MAP4K2

1.31e-0518912160739baad9a7da511dd3d7249f84299aee88370a1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK3 TACC2 CRIP2 ATRNL1 LGR6 NPAS4

1.35e-051901216938d1f66094b1c94606e0d40213a39e5112f3322
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 PERM1 BCAT2 PKHD1 ROBO3 ALDOC

1.39e-051911216297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 PERM1 BCAT2 PKHD1 ROBO3 ALDOC

1.39e-051911216e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCellDiffer-Basal|World / shred by cell class for mouse tongue

ANK3 BCAT2 LGR6 ALDOA ALDOC MOCS2

1.51e-051941216851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLNC PDGFRB CRIP2 THBS3 HMCN2 MBNL2

1.61e-05196121624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC ARPP21 ANK3 BCAT1 COL5A3 FGFR4

1.70e-0519812165e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLNC SRCAP CRIP2 THBS3 DBNDD1 ALDOA

1.70e-051981216399760b6b6fef8639ded53b14f251b9fce600e81
ToppCellmild-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDGFRB SH2B1 TRIM3 ARVCF ELK1 LGR6

1.80e-052001216ca0a08bf162c954f037a56aa0cbb8b5d7c6ffec0
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

DOCK3 NAGK ZNF843 TACC2 VWA7

2.09e-0512212151cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCelldroplet-Liver-Npc-21m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRB MCM3AP AGMO FGFR4

4.21e-05711214cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 CNTN6 PKHD1 ATP2B3 HYDIN

4.78e-05145121596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK3 FLNC HMCN2 ATRNL1 LGR6

6.55e-051551215cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

DHX57 ITGAM DBNDD1 MCM3AP LGR6

6.76e-05156121525b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ARPP21 RGS14 ICAM5 RNF39 ALDOA

8.31e-051631215218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

NUGGC C16orf96 BTN1A1 UBAP1L

8.52e-0585121467336aa7ec02b64595ce7d5222d43cead92eb52e
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Striatum / BrainAtlas - Mouse McCarroll V32

NUGGC C16orf96 BTN1A1 UBAP1L

8.52e-05851214a7a5d82924cd4a41ab87b1abf13143635882a4b2
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

NUGGC C16orf96 BTN1A1 UBAP1L

8.52e-0585121486c5d71b66ff55c44d2d457865dda72e07e5ec53
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANK3 BCAT1 TACC2 IGFLR1 KIRREL1

8.56e-051641215b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANK3 BCAT1 TACC2 IGFLR1 KIRREL1

8.56e-0516412153aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 BATF2 MMACHC ZFYVE26 ELK1

9.32e-051671215a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

COL5A3 HMCN2 ATRNL1 LGR6 ROBO3

9.32e-051671215c4e321bb87512ea839f324c92c0f1afea891483f
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIAA1549 PERM1 CNTN6 NLRP10 ICAM5

9.59e-051681215d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIRREL3 RAPGEF3 ATRNL1 PKHD1 HYDIN

9.59e-051681215a086c306be430adf0632ba53e98cd8014d2de330
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

PERM1 C16orf96 BATF2 HMCN2

9.75e-058812145fdfc72988dcbb7d2025866b2b00eab8f11f332f
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PERM1 C16orf96 BATF2 HMCN2

9.75e-05881214b9874366925fa1c08a74b14c3c6e127b9dffa23e
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAF2 PDGFRB VWA7 CNTN5 KIRREL1

9.86e-05169121587116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVC2 PERM1 BATF2 MMACHC AGMO

1.01e-0417012158d3c51364a332020810836e2055c60893c10d7f3
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|368C / Donor, Lineage, Cell class and subclass (all cells)

ITGAM MMACHC PRDM11 RAPGEF3 TRAPPC14

1.04e-04171121526b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell356C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

SH2B1 KIAA2013 AP1G1 HEATR5B SLC26A6

1.07e-0417212154977e1f4deae781750e27a8054deccd336cfb74a
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PANX2 UBAP1L HSF4 ALDOB ATP2B3

1.10e-0417312157e3897868dd3f6e4974f593c60649a543ffc8693
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NUGGC ARPP21 KIAA1549 AQP7 PKHD1

1.22e-0417712152f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RAPGEF3 ATRNL1 PKHD1 KIRREL1 HYDIN

1.26e-041781215544379f5a6145429762258d426b876bb36c112f5
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 PERM1 SYT8 MMRN2 ALDOB

1.29e-041791215a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARPP21 KIAA1549 ICAM5 AGMO SLC26A6

1.29e-041791215d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARPP21 IGFLR1 KIRREL3 SEC61B FUT7

1.29e-0417912154808469096cd6bec2bdfcf4fc55aa324757600c3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA4 BCAT1 TACC2 CNTN6 PKHD1

1.29e-04179121504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARPP21 IGFLR1 KIRREL3 SEC61B FUT7

1.29e-0417912154d55718c6afd8a038d93cc77b9b08171dab9976f
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 THAP8 PKHD1 FGFR4

1.31e-049512143699ea16660a22ea79fecfea56ece2dfb0f13467
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 THAP8 PKHD1 FGFR4

1.31e-04951214cbfe615d880913bafaf5e7e8d24c3ec14a9351ce
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 THAP8 PKHD1 FGFR4

1.31e-0495121427ac23b87747434a3084cc087e7b884e68f0eab9
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ANK3 AP1G1 MBNL2 MACF1 FUT8

1.36e-041811215f2315414e714ac86211546a935660c4be6e85f1b
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PANX2 DBNDD1 UBAP1L HSF4 ATP2B3

1.39e-04182121504ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 DYNC2LI1 CNTN5 PKHD1 HYDIN

1.43e-04183121592fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellPericytes-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

FLNC PDGFRB COL5A3 CRIP2 KIRREL1

1.47e-0418412153d2d55d0f22874be21665ab37da710482f77fc36
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARPP21 CRIP2 RGS14 ICAM5 RNF39

1.54e-04186121556c139e679d640ea901ead657a8e8887e0fca098
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 ZNF668 ARVCF RAPGEF3 MMRN2

1.54e-0418612152cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 ZNF668 ARVCF RAPGEF3 MMRN2

1.54e-04186121590d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NUGGC ARPP21 KIAA1549 AQP7 AGMO

1.54e-041861215a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellmild-unassigned|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDGFRB TRIM3 ARVCF ELK1 LGR6

1.54e-0418612155b2e1a58916f392fa1156bf9210df528775248ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 AGMO PKHD1 FUT8 HYDIN

1.54e-041861215b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANK3 TACC2 ATRNL1 LGR6

1.62e-041881215293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 FLNC HMCN2 ATRNL1 LGR6

1.62e-041881215c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 FLNC TACC2 ATRNL1 LGR6

1.62e-0418812154d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK3 TACC2 CRIP2 ATRNL1 LGR6

1.62e-041881215f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 PDGFRB COL5A3 ATRNL1 LGR6

1.66e-0418912157ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 FLNC TACC2 THBS3 LGR6

1.66e-0418912154dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 FLNC TACC2 THBS3 LGR6

1.66e-0418912150d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 PDGFRB COL5A3 ATRNL1 LGR6

1.75e-0419112157853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ANK3 CRIP2 CEP68 FUT7 HSF4

1.75e-04191121525dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCellfacs-Brain_Non-Myeloid-Striatum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 ANK3 RGS14 CNTN5 NIPA1

1.83e-041931215d8ccfb780a75bdf9141f41fb29a076958601ebb4
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK3 TACC2 CRIP2 ATRNL1 LGR6

1.83e-041931215000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellControl-B_memory-3|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 ITGAM CRIP2 CORO7 FUT7

1.92e-041951215135234f068da3e8db7213b53c09ed6d1d0cdc351
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 ANK3 TACC2 MACF1 HYDIN

1.97e-041961215af4cdc61830685a888a1209826c23bcf54a43084
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZHX3 FLNC ANK3 SLC39A1 FGFR4

1.97e-04196121597ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 ANK3 TACC2 MACF1 HYDIN

1.97e-0419612156d02d494196e3f857d53eea46d9419690d43beca
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZHX3 FLNC ANK3 HNRNPF FGFR4

2.02e-0419712155bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCellControl-B_memory-3|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 ITGAM CRIP2 CORO7 FUT7

2.02e-041971215b86385c6c1d52ef4e3d855004d77afab61556978
ToppCelldistal-1-Hematologic-Plasmacytoid_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ARPP21 PANX2 IGFLR1 KIRREL3 FUT7

2.02e-041971215166d47359df9279ea8c3946f10bd3d4b88c95857
ToppCellLPS_anti-TNF|World / Treatment groups by lineage, cell group, cell type

IGFLR1 ITGAM SEC61B ALDOA MTCH2

2.02e-0419712157768e613fa48a6ec4a3902559310b51345a7fe91
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLNC PDGFRB CRIP2 THBS3 HMCN2

2.06e-0419812154f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NUGGC PANX2 VWA7 SYT8 UTP3

2.06e-04198121524bc53bd8ef8f4f2f4fc377aeee75126ad5d311f
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCA4 BCAT1 CNTN6 ICAM5 PKHD1

2.06e-041981215b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TACC2 CRIP2 THBS3 LGR6 ALDOC

2.11e-041991215a207b4891881149d4c50721310690fd794157723
ToppCellMild/Remission-B_memory-3|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 ITGAM CRIP2 CORO7 FUT7

2.11e-041991215493d043beef70b60338cc199db82592cdc6e635d
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCA4 BCAT1 CNTN6 ICAM5 PKHD1

2.11e-041991215a270630626df614f8605abddb7dee7c4d74f6149
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK3 TACC2 ATRNL1 ALDOC HYDIN

2.11e-04199121519a97e27a4758e794ce7246d295e112b47931a48
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

BCAT1 CNTN6 PKHD1 STRC SON

2.16e-0420012152dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABCA4 BCAT1 CNTN6 ICAM5 PKHD1

2.16e-042001215ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DOCK3 ANK3 TACC2 ATRNL1 LGR6

2.16e-042001215c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CRIP2 CEP68 SYT8 MMRN2 FUT8

2.16e-042001215ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ZFPL1 CNTN6 PKHD1

2.31e-041101214c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TCAF2 COL5A3 BATF2 HMCN2

2.56e-0411312140651fb7a7e1ea84b8365059e5ed85bf6c082da1a
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8-MURAL_Mural.Acta2Rgs5.Kcnj8-Abcc9_(Mural.Acta2Rgs5.Kcnj8-Abcc9)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TCAF2 COL5A3 BATF2 HMCN2

2.56e-0411312140e153efddd061d7510dfc3859cc8b1a7984fa70e
DrugAldol

BCAT1 BCAT2 XPNPEP1 ALDOA ALDOB ALDOC

1.77e-08331196CID000007897
DrugAlbendazole [54965-21-8]; Down 200; 15uM; MCF7; HT_HG-U133A

ZHX3 DNAH3 TRIM3 ZFPL1 THBS3 MAP1S ELK1 FGFR4 TRAPPC14 SLC26A6

8.79e-08197119107164_DN
Drugacetol phosphate

ALDOA ALDOB ALDOC

1.39e-0731193CID000150865
Drug4-hydroxy-9-fluorenone

ALDOA ALDOB ALDOC

1.39e-0731193CID000016139
DrugHtfp

ALDOA ALDOB ALDOC

1.39e-0731193CID000125055
DrugDIDIT

ALDOA ALDOB ALDOC

1.39e-0731193CID000196082
Drug2-keto-3-deoxy- l-lyxonate

ALDOA ALDOB ALDOC

1.39e-0731193CID000192781
Drugandroisoxazole

ALDOA ALDOB ALDOC

1.39e-0731193CID000009676
Drug2-keto-3-bromobutyrate

ALDOA ALDOB ALDOC

1.39e-0731193CID000191968
Drug3-isochromanone

ALDOA ALDOB ALDOC

1.39e-0731193CID000078092
Drug5-deoxy-5-fluoro-L-sorbose

ALDOA ALDOB ALDOC

1.39e-0731193CID000191809
DrugD-ribulose-1-p

ALDOA ALDOB ALDOC

1.39e-0731193CID000000615
Drug4-hydroxy-2-ketopimelate

ALDOA ALDOB ALDOC

1.39e-0731193CID000000553
DrugAC1L19F1

ALDOA ALDOB ALDOC

1.39e-0731193CID000000519
Drugformylacetate

ALDOA ALDOB ALDOC

5.55e-0741193CID000075269
Drugdihydroxyacetone sulfate

ALDOA ALDOB ALDOC

5.55e-0741193CID000439751
DrugC06441

ALDOA ALDOB ALDOC

5.55e-0741193CID000441020
Drug3-hydroxy-1-indanone

ALDOA ALDOB ALDOC

5.55e-0741193CID000176448
Drugl-123

ALDOA ALDOB ALDOC

5.55e-0741193CID000093552
DrugKetotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A

ZHX3 EPM2A ANK3 DHX57 THBS3 MAP1S ELK1 TRAPPC14 SLC26A6

1.01e-0619811997199_DN
Drug1,3-dioxan-5-one

ALDOA ALDOB ALDOC

1.38e-0651193CID009793707
DrugAC1L4F2K

ALDOA ALDOB ALDOC

1.38e-0651193CID000184526
Druggamma-oxalocitramalate

ALDOA ALDOB ALDOC

1.38e-0651193CID000000130
Drug2,3-dihydroxy-p-cumate

ALDOA ALDOB ALDOC

1.38e-0651193CID000029587
DrugAC1NX490

ALDOA ALDOB ALDOC

1.38e-0651193CID005743230
Drugphosphoglycollamide

ALDOA ALDOB ALDOC

1.38e-0651193CID000191768
DrugD-erythrulose 1-phosphate

ALDOA ALDOB ALDOC

1.38e-0651193CID000152153
Drughydroxypyruvaldehyde phosphate

ALDOA ALDOB ALDOC

1.38e-0651193CID000193787
DrugManNAc-6-P

NAGK PPRC1 ALDOA ALDOB ALDOC

2.61e-06421195CID000000898
Drugmycestericin D

ALDOA ALDOB ALDOC

2.75e-0661193CID006439504
DrugC02783

ALDOA ALDOB ALDOC

2.75e-0661193CID000439805
Drug2,2-dimethyl-1,3-dioxan-5-one

ALDOA ALDOB ALDOC

2.75e-0661193CID002733141
Drug2-(N-decyl)aminonaphthalene-6-sulfonic acid

ALDOA ALDOB ALDOC

2.75e-0661193CID000189836
Drugparapyruvate

ALDOA ALDOB ALDOC

2.75e-0661193CID000440249
Drugacetyldithio-CoA

ALDOA ALDOB ALDOC

2.75e-0661193CID003082679
Drug0 Gz

ALDOA ALDOB ALDOC

2.75e-0661193CID000000372
Drugchloroacetol phosphate

ALDOA ALDOB ALDOC

2.75e-0661193CID000168137
Drugacenaphthenone

ALDOA ALDOB ALDOC

4.80e-0671193CID000075229
DrugDAPpNP

ALDOA ALDOB ALDOC

4.80e-0671193CID005492375
Drug5-deoxy-D-xylulose-1-phosphate

ALDOA ALDOB ALDOC

4.80e-0671193CID000192931
DrugZ-Glu-Tyr

ALDOA ALDOB ALDOC

4.80e-0671193CID000096820
DrugC0447

ALDOA ALDOB ALDOC

4.80e-0671193CID000128786
Drug3-hydroxy-4-oxobutyl-1-phosphonate

ALDOA ALDOB ALDOC

7.65e-0681193CID003016813
DrugL-rhamnulose-1-phosphate

ALDOA ALDOB ALDOC

7.65e-0681193CID000439413
Drugamorphin

ALDOA ALDOB ALDOC

7.65e-0681193CID000122792
DrugCarisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

ZHX3 DNAH3 EPM2A SRCAP RGS14 ARVCF ELK1 MAP4K2

9.41e-0619711984955_UP
DrugGuanethidine sulfate [60-02-6]; Down 200; 13.4uM; PC3; HT_HG-U133A

SLC39A1 ASIC3 SRCAP PITPNM1 CEP68 RGS14 THBS3 DBNDD1

9.76e-0619811985731_DN
Drug2-oxopentenoate

ALDOA ALDOB ALDOC

1.14e-0591193CID000000976
Drugtartronate semialdehyde

ALDOA ALDOB ALDOC

1.63e-05101193CID000001122
DrugSM-8

ALDOA ALDOB ALDOC

1.63e-05101193CID000486037
Drugalpha-ketobutyrate

BCAT1 BCAT2 ALDOA ALDOB ALDOC

2.14e-05641195CID000000058
DrugIchiba acid

ALDOA ALDOC

2.71e-0521192CID000440403
Drug3-HM

ALDOA ALDOC

2.71e-0521192CID000439464
Drugbromohydroxyacetone phosphate

ALDOA ALDOC

2.71e-0521192CID000152675
Druganthracene diol

ALDOA ALDOC

2.71e-0521192CID000155464
Drug1trd

ALDOA ALDOB ALDOC

2.96e-05121193CID000004797
Drugdihydropteridine

ALDOA ALDOB ALDOC

2.96e-05121193CID000000167
Drugb-3p

BTN1A1 ALDOA ALDOB ALDOC

3.28e-05351194CID000125132
Drugfuculose

ALDOA ALDOB ALDOC

3.83e-05131193CID000000841
Drugbeta-isopropyl-tropolone

ALDOA ALDOB ALDOC

4.86e-05141193CID000080297
Drug2-keto-4-hydroxyglutarate

ALDOA ALDOB ALDOC

4.86e-05141193CID000000599
DrugLabetalol hydrochloride [32780-64-6]; Up 200; 11uM; HL60; HG-U133A

ITGAM SH2B1 THBS3 DYNC2LI1 ELK1 TRAPPC14 ALDOC

6.43e-0519011971550_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

EPM2A BCAT1 ZNF407 ITGAM MCM3AP FUT7 ALDOB

6.87e-0519211973332_UP
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; PC3; HT_HG-U133A

ANK3 RBM42 MMACHC RGS14 ROBO3 BRD1 TRAPPC14

6.87e-0519211977280_DN
DrugCefalonium [5575-21-3]; Up 200; 8.8uM; MCF7; HT_HG-U133A

EPM2A ASIC3 IGFLR1 TRIM3 PITPNM1 ARVCF MBNL2

7.10e-0519311977341_UP
DrugPyrilamine maleate [59-33-6]; Up 200; 10uM; PC3; HT_HG-U133A

ZHX3 ZNF407 SH2B1 RGS14 MBNL2 MMRN2 ACSBG2

7.33e-0519411975869_UP
Drugglycidaldehyde

ALDOA ALDOB ALDOC

7.42e-05161193CID000013002
DrugLY294002; Down 200; 10uM; PC3; HT_HG-U133A

EPM2A SH2B1 TRIM3 PITPNM1 ZNF668 KIRREL1 TRAPPC14

7.82e-0519611975942_DN
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; PC3; HT_HG-U133A

ZHX3 ZNF668 THBS3 ELK1 FGFR4 BRD1 MAP4K2

7.82e-0519611976335_DN
Drugrosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A

ZHX3 RBM42 SH2B1 CEP68 ARVCF ELK1 ROBO3

7.82e-0519611971658_UP
DrugClozapine [5786-21-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

TACC2 SH2B1 ZFPL1 PITPNM1 CEP68 MAP1S CBX7

8.07e-0519711972644_DN
DrugTrichlorfon [52-68-6]; Down 200; 15.6uM; PC3; HT_HG-U133A

DHX57 SRCAP IGFLR1 ROBO3 BRD1 MAP4K2 SLC26A6

8.07e-0519711977287_DN
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A

SRCAP TRIM3 ZFPL1 RGS14 ARVCF MAP4K2 SLC26A6

8.07e-0519711973355_DN
Drugrofecoxib; Down 200; 10uM; HL60; HG-U133A

DPH2 DNAH3 ANK3 BCAT1 COL5A3 ARVCF TRAPPC14

8.07e-051971197371_DN
DrugChlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A

ZHX3 EPM2A DHX57 SRCAP MAP1S ARVCF ELK1

8.07e-0519711973235_DN
DrugAmidopyrine [58-15-1]; Down 200; 17.2uM; MCF7; HT_HG-U133A

SH2B1 TRIM3 ZNF668 CBX7 MACF1 ARHGEF2 ROBO3

8.07e-0519711972222_DN
Drug3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; HL60; HT_HG-U133A

IGFLR1 ZFPL1 CEP68 THBS3 DYNC2LI1 MCM3AP ALDOB

8.07e-0519711973044_DN
DrugL-Valine

BCAT1 PCCB

8.10e-0531192DB00161
Drug3,3,3-trifluoropropanoic acid

ALDOA ALDOC

8.10e-0531192CID002777972
Drug4-fluorothreonine

ALDOA ALDOC

8.10e-0531192CID000128057
Drug(4S,7R,8R,9R,13Z,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methylthiazol-4-yl)vinyl]-1-oxacyclohexadec-13-ene-2,6-dione

ALDOA ALDOC

8.10e-0531192CID009869661
DrugAC1L19ID

ALDOA ALDOC

8.10e-0531192CID000000560
DrugC11 -427

ALDOA ALDOC

8.10e-0531192CID000443195
DrugBenperidol [2062-84-2]; Up 200; 10.4uM; PC3; HT_HG-U133A

ZHX3 EPM2A THBS3 DBNDD1 ARVCF ELK1 ARHGEF2

8.33e-0519811974196_UP
Drugtolbutamide; Down 200; 100uM; MCF7; HG-U133A

FLNC SRCAP MMACHC CEP68 ARVCF ARHGEF2 TRAPPC14

8.60e-051991197142_DN
DrugSulfabenzamide [127-71-9]; Down 200; 14.4uM; PC3; HT_HG-U133A

SLC39A1 IGFLR1 SH2B1 ZFPL1 THBS3 DBNDD1 ARHGEF2

8.60e-0519911976634_DN
Drughaloperidol; Up 200; 10uM; HL60; HT_HG-U133A

ITGAM MBNL2 DYNC2LI1 ICAM5 MCM3AP CBX7 MMRN2

8.87e-0520011972704_UP
Drugtrimethylaminobutyraldehyde

ALDOA ALDOB ALDOC

8.97e-05171193CID000000133
Drug3HPP

ALDOA ALDOB ALDOC

8.97e-05171193CID000000091
DrugZnATP

ALDOA ALDOB ALDOC

8.97e-05171193CID006455240
DrugN-bromoacetylethanolamine phosphate

ALDOA ALDOB ALDOC

8.97e-05171193CID000188343
Drug2-deoxyribose 5-phosphate

ALDOA ALDOB ALDOC

1.07e-04181193CID000150629
Drug1H-imidazole hydrochloride

ALDOA ALDOB ALDOC

1.07e-04181193CID000518985
DrugAC1L2YVP

ALDOA ALDOB ALDOC

1.27e-04191193CID000080135
Drugmalonate semialdehyde

ALDOA ALDOB ALDOC

1.27e-04191193CID000000868
DrugAC1Q6S6V

ALDOA ALDOB ALDOC

1.49e-04201193CID000000475
Drug9-fluorenone-1-carboxylic acid

ALDOA ALDOC

1.61e-0441192CID000074083
DrugAC1L9A8P

ALDOA ALDOC

1.61e-0441192CID000440943
Drugphenanthrene trans-3,4-dihydrodiol

ALDOA ALDOC

1.61e-0441192CID000119398
DrugDHMP

ALDOA ALDOC

1.61e-0441192CID000098784
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

1.59e-0521182DOID:0110471 (implicated_via_orthology)
DiseaseAdenoid Cystic Carcinoma

SRCAP CNTN6 FGFR4 BRD1 SON

5.22e-051001185C0010606
DiseaseEllis-Van Creveld Syndrome

EVC2 DYNC2LI1

9.46e-0541182C0013903
Diseaseglucagon measurement, glucose tolerance test

MACF1 UTP3

2.35e-0461182EFO_0004307, EFO_0008463
DiseaseN-acetylserine measurement

DOCK3 ABHD14B

2.35e-0461182EFO_0800038
Diseasehemoglobin A1 measurement

ZHX3 CACUL1 THBS3 PRDM11 ARVCF CNTN5 AGMO MACF1 MAP4K2

2.50e-045201189EFO_0007629
Diseasefructosamine measurement

CNTN5 MAP4K2

3.29e-0471182EFO_0009303
DiseaseColorectal Carcinoma

FLNC DNAH3 EVC2 ABCA4 CACUL1 ICAM5 MCM3AP PKHD1 MMRN2 LGR6

5.30e-0470211810C0009402
DiseaseSchizophrenia and related disorders

ARVCF FUT8

5.60e-0491182C0809983
Diseaseserum urea measurement

RGS14 THBS3 FGFR4 LGR6 ARHGEF2

1.15e-031951185EFO_0009795
DiseaseMalignant neoplasm of breast

ABCA4 TACC2 PANX2 CNTN6 ZNF668 THBS3 ICAM5 MACF1 ZFYVE26 LGR6 ALDOA HSPA14

1.26e-03107411812C0006142
Diseaserevision of total hip arthroplasty

VWA7 STRCP1

1.40e-03141182EFO_0020973
DiseaseObesity

ITGAM AQP7 SH2B1 RAPGEF3 MTCH2

1.43e-032051185C0028754
Diseaseloneliness measurement

EPM2A CNTN6 CNTN5 MACF1

1.58e-031241184EFO_0007865
DiseaseN-acetylmethionine measurement

DOCK3 ABHD14B

1.61e-03151182EFO_0021427
Diseasecholesterol to total lipids in IDL percentage

BCAT2 MACF1 PCCB

1.81e-03601183EFO_0022233
Diseaseblood urea nitrogen measurement

HNRNPF RGS14 THBS3 PKHD1 LGR6 FUT8 PCCB

2.32e-034521187EFO_0004741
DiseaseDisorder of organic acid metabolism

MMACHC PCCB

2.33e-03181182cv:C1263739
Diseaseneuroticism measurement

DOCK3 ARPP21 KIRREL3 PRDM11 ARVCF MBNL2 CNTN5 PKHD1 PCCB MTCH2

3.58e-0390911810EFO_0007660
Diseaserisk-taking behaviour

ARPP21 SH2B1 KIRREL3 THBS3 AP1G1 ATRNL1 ALDOA MTCH2 NPAS4

3.64e-037641189EFO_0008579
Diseasewaist-hip ratio

ZHX3 ARPP21 ANK3 ZNF407 COL5A3 SH2B1 KIAA2013 RAPGEF3 CNTN5 FGFR4 CORO7 PCCB

3.73e-03122611812EFO_0004343
DiseaseBMI-adjusted fasting blood glucose measurement

AGMO MAP4K2

3.80e-03231182EFO_0008036

Protein segments in the cluster

PeptideGeneStartEntry
LITAGGENVPPIPVE

ACSBG2

516

Q5FVE4
GVTIPAPPLDVLKIG

BRD1

961

O95696
EEAGLPLQVILTPPE

ELK1

211

P19419
VEPGLGRALPPEVKV

ELK1

236

P19419
VRQVPVGPDGLPLLD

ARVCF

136

O00192
LATPPLDGIILPGVT

BCAT1

276

P54687
QPPRLEAEGGLISPV

CEP68

41

Q76N32
IGCPPLVLLDEPTTG

ABCA4

2086

P78363
VIGPPEPILAVVGED

BTN1A1

31

Q13410
PGKPRLGLSEEIPEV

AGMO

306

Q6ZNB7
NGIVPIVEPEILPDG

ALDOC

181

P09972
NGLVPIVEPEVIPDG

ALDOB

181

P05062
LPPGDPQLIAIIVGQ

BOD1L2

31

Q8IYS8
NGIVPIVEPEILPDG

ALDOA

181

P04075
GPGVELLLTPREPAL

ARHGEF2

671

Q92974
ALLGVLLSVPGPPVL

FGFR4

6

P22455
ETGVPGLLTPLPDLD

DPH2

16

Q9BQC3
VLVPVEGGEQSLPPE

ARMCX5

231

Q6P1M9
LLPLEAATGIPPGSI

ARPP21

466

Q9UBL0
ILPPEKEGALPRQVG

ATP2B3

526

Q16720
EPPGGQLLAVPAVSV

CACUL1

51

Q86Y37
PGPPGIVIVEEITES

CNTN5

671

O94779
VLIQVGYEPLPPTIG

MTCH2

26

Q9Y6C9
PEIDPVLFQGKIGLP

NAGK

251

Q9UJ70
QEVLGAPVPGIPTAV

RBM42

46

Q9BTD8
GITIPLPSLGEVSQP

KIAA1549

296

Q9HCM3
EAGLTPDILIPPEGI

MAP4K2

686

Q12851
VVDALELGPPVVISP

ABHD14B

96

Q96IU4
LLGGNDITPVIPTAP

AP1G1

631

O43747
GVVVPPAVAGARPEL

EPM2A

6

O95278
VATPSLELGPIPAGE

MAP1S

606

Q66K74
LVLLTVFAGGPVPLP

LGR6

581

Q9HBX8
QPPLARGELEGLIPV

NLRP10

41

Q86W26
PLVDIRVTGPVPGAL

MMRN2

801

Q9H8L6
VPPELIGDLDPLTNI

HMCN2

2356

Q8NDA2
LPLVVLVPSPGGDAV

MCM3AP

1496

O60318
HELIDPFPVPLVIIG

DYNC2LI1

171

Q8TCX1
SAPGVVLGPEDLPVE

CORO7

116

P57737
LVTLEGVPAAVPGQP

ICAM5

351

Q9UMF0
PLQVAVLGPTGVAEP

FLNC

1476

Q14315
LVAGTVPVVLGPPRA

FUT7

246

Q11130
LEPIGELAPVPIVGA

EVC2

1246

Q86UK5
PALPGTEALVIGILV

AQP7

196

O14520
EPPIIDQLGLGVSPG

ASIC3

246

Q9UHC3
PEPGLLLEVEEPGTE

PELP1

1001

Q8IZL8
RGVVLLPGIEVPDLP

MMACHC

161

Q9Y4U1
LLTIPPAEAEGVPLV

MACF1

2136

Q9UPN3
IPLITFVDVPGFLPG

PCCB

386

P05166
GPLSVDVPLVPEGLL

NPAS4

596

Q8IUM7
DNLLPGVPLILPVSG

HYDIN

1431

Q4G0P3
EGALQVLPPLVDVIP

TTC26

271

A0AVF1
PGPLPLGVSVIDASV

HEATR5B

771

Q9P2D3
IGPFLGVTLVPQPEV

DOCK3

1096

Q8IZD9
PGLELGLELEPVPAL

C16orf96

336

A6NNT2
GIISDLFPGVVLPKP

DNAH3

1651

Q8TD57
EVGGIPVPAPGLLQV

DBNDD1

41

Q9H9R9
PPGAILVFLPGLAEI

DHX57

846

Q6P158
LSLGPAVVAEPPVQL

BATF2

156

Q8N1L9
EELIVLLDPEPGPGG

IGFLR1

261

Q9H665
GAPELVDKGPLVPTL

CBX7

121

O95931
PAGAQFLGPVIVEIP

ANK3

1051

Q12955
LRGPLEGAPKPIAIE

ATRNL1

1296

Q5VV63
LSAVADIIVRGPPGP

CNTN6

586

Q9UQ52
PLVPERGEPELAVKG

HSF4

421

Q9ULV5
PVTPGVGLVPTEILP

MBNL2

136

Q5VZF2
VLIPPEDTRIDGGPV

KIRREL1

116

Q96J84
LTVLVPPDDPVILGG

KIRREL3

141

Q8IZU9
LAEGPQVTGPIEVPA

CRIP2

81

P52943
LELVTPPLNGVILPG

BCAT2

281

O15382
PLLELVEQGIIPPGK

UTP3

246

Q9NQZ2
PRDGVIIGLNPLPDV

SLC38A10

1066

Q9HBR0
PTVLVTPLGALGVPF

NIPA1

91

Q7RTP0
EGVLGPAVPLPLQAL

PERM1

671

Q5SV97
LAGPVPVDPGLVDLA

PPRC1

601

Q5VV67
FVPVPLPVVEGGLEE

COL5A3

1501

P25940
IGLGPVAPFVAAIPL

MFSD5

196

Q6N075
QGLVVTPPGPELVLN

PDGFRB

31

P09619
GPRLPQDVGDLIAIP

PANX2

641

Q96RD6
ELLNSIPPDEVIPIG

HSPA14

356

Q0VDF9
IPPDEVIPIGAAIEA

HSPA14

361

Q0VDF9
IVPNGITLPVDPEGK

HNRNPF

136

P52597
SLRIPEGPIDQGPAI

FUT8

66

Q9BYC5
TAIPGLIPDLVAGTP

SYT8

31

Q8NBV8
LVLQPGDEIAVIPPI

MOCS2

71

O96033
GGVPEELVPVVELVP

SH2B1

686

Q9NRF2
LIPEGVVLVDIPGTG

NUGGC

281

Q68CJ6
AIPVSGPVRLVVLGP

THAP8

121

Q8NA92
IRVIPLEDPLGPAVI

RSPRY1

146

Q96DX4
SPVPVPENDLVGIVG

PRSS29P

56

A6NIE9
VPRGPIPSELLLIGE

TCAF2

21

A6NFQ2
DVVGNIPAGLVPPVA

SLC26A6

321

Q9BXS9
PVGIPDRAALTIPQG

PRDM11

136

Q9NQV5
LPTPIPGEVVLVLLA

SLC26A10

226

Q8NG04
IPGPGDDVLILPNRT

PKHD1

2756

P08F94
EVPNPLPLIVGSSVG

ITGAM

1101

P11215
LIVADPVLEPQLIPG

SRCAP

2901

Q6ZRS2
VEVLLGALVPGGPPT

STRC

141

Q7RTU9
LTFPVPPERALGIGV

PITPNM1

981

O00562
PRVGALPDVVPEGTL

RAPGEF3

26

O95398
LPEGSRVGVDPLIIP

XPNPEP1

111

Q9NQW7
GVPPAQELVVGLALP

ZNF668

421

Q96K58
EDSPGLKVGPVPVLV

SEC61B

61

P60468
PPGAKEGLEVPLIAV

TRAPPC14

326

Q8WVR3
PPVPVGLEVKLGALV

SLC39A1

21

Q9NY26
AGVGVPSAPVLVQLP

ROBO3

851

Q96MS0
TGQPLVGIETLPPDL

USP25

671

Q9UHP3
LLDGPPGVDVTLLPA

TACC2

1451

O95359
LGVEELGQLPPVEGP

RGS14

221

O43566
ALAPIPPAEVDGLEI

THBS3

156

P49746
VIGTEPLPGPELSVP

UBAP1L

16

F5GYI3
EGILDTLEGPNIPPI

YIPF3

301

Q9GZM5
GLPAVPAVPLGGLEV

ZNF843

236

Q8N446
VEVLLGALVPGGPPT

STRCP1

141

A6NGW2
VGSVVPGPILPEQLA

ZNF407

1921

Q9C0G0
ILTELPPGVQDEPGL

ZNF407

2171

Q9C0G0
VELEVNLLTPGAVPP

PTCD1

436

O75127
PLIGTVPVLPAGIAQ

ZHX3

256

Q9H4I2
VPEGAELGQVPLEPV

VWA7

661

Q9Y334
LRALQGPDSVPPGVV

ZFYVE26

201

Q68DK2
GLPLVTAAVELPEQP

SON

481

P18583
GLGLPLIDEVVSPEP

ZFPL1

131

O95159
GEVPVLVEPPGLEDV

TSC2

1306

P49815
ITGPDGTRLPVPVVD

TRIM3

366

O75382
ALTAPEPTLLGGVEP

RNF39

346

Q9H2S5
EVVPLGPGVPALVAN

KIAA2013

81

Q8IYS2
PPTLLTLQEPVTGEG

NEXN-AS1

181

Q8NBZ9