Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR3 FGFR2

9.51e-065202GO:0005007
GeneOntologyMolecularFunctionfibroblast growth factor binding

FGFR3 FGFR2

3.30e-0427202GO:0017134
GeneOntologyBiologicalProcessfibroblast growth factor receptor apoptotic signaling pathway

FGFR3 FGFR2

2.68e-063202GO:1902178
GeneOntologyBiologicalProcessnegative regulation of mitotic nuclear division

CDK5RAP2 FGFR3 FGFR2

3.13e-0564203GO:0045839
GeneOntologyBiologicalProcessnegative regulation of nuclear division

CDK5RAP2 FGFR3 FGFR2

4.64e-0573203GO:0051784
GeneOntologyBiologicalProcesslung alveolus development

ABCA12 FGFR3 FGFR2

5.04e-0575203GO:0048286
GeneOntologyBiologicalProcesspositive regulation of cell proliferation in bone marrow

FGFR3 FGFR2

5.86e-0512202GO:0071864
GeneOntologyBiologicalProcesspositive regulation of phospholipase activity

FGFR3 FGFR2

8.07e-0514202GO:0010518
GeneOntologyBiologicalProcessregulation of mitotic metaphase/anaphase transition

CDK5RAP2 PBRM1 CDC6

1.02e-0495203GO:0030071
GeneOntologyBiologicalProcessregulation of cell proliferation in bone marrow

FGFR3 FGFR2

1.06e-0416202GO:0071863
GeneOntologyBiologicalProcessregulation of metaphase/anaphase transition of cell cycle

CDK5RAP2 PBRM1 CDC6

1.12e-0498203GO:1902099
GeneOntologyBiologicalProcessmitotic cell cycle process

CDK5RAP2 FGFR3 FGFR2 PBRM1 SEPTIN7 CDC6

1.16e-04854206GO:1903047
GeneOntologyBiologicalProcessmetaphase/anaphase transition of mitotic cell cycle

CDK5RAP2 PBRM1 CDC6

1.19e-04100203GO:0007091
GeneOntologyBiologicalProcessmetaphase/anaphase transition of cell cycle

CDK5RAP2 PBRM1 CDC6

1.30e-04103203GO:0044784
GeneOntologyBiologicalProcesscell proliferation in bone marrow

FGFR3 FGFR2

1.35e-0418202GO:0071838
GeneOntologyBiologicalProcessvasculogenesis involved in coronary vascular morphogenesis

FGFR2 PBRM1

1.35e-0418202GO:0060979
GeneOntologyBiologicalProcesslens fiber cell development

FGFR3 FGFR2

1.35e-0418202GO:0070307
GeneOntologyBiologicalProcessnegative regulation of mitotic cell cycle

CDK5RAP2 FGFR3 FGFR2 CDC6

1.39e-04282204GO:0045930
GeneOntologyBiologicalProcessregulation of sister chromatid segregation

CDK5RAP2 PBRM1 CDC6

1.62e-04111203GO:0033045
GeneOntologyBiologicalProcessregulation of organelle organization

CDK5RAP2 FGFR3 FGFR2 PBRM1 BICD1 SEPTIN7 CDC6

1.77e-041342207GO:0033043
GeneOntologyBiologicalProcessregulation of phospholipase activity

FGFR3 FGFR2

2.04e-0422202GO:0010517
GeneOntologyBiologicalProcessregulation of mitotic cell cycle

CDK5RAP2 FGFR3 FGFR2 PBRM1 CDC6

2.11e-04594205GO:0007346
GeneOntologyBiologicalProcesspositive regulation of lipase activity

FGFR3 FGFR2

2.64e-0425202GO:0060193
GeneOntologyBiologicalProcessregulation of mitotic nuclear division

CDK5RAP2 FGFR3 FGFR2

2.82e-04134203GO:0007088
GeneOntologyBiologicalProcessmitotic cell cycle

CDK5RAP2 FGFR3 FGFR2 PBRM1 SEPTIN7 CDC6

2.97e-041014206GO:0000278
GeneOntologyBiologicalProcessregulation of chromosome segregation

CDK5RAP2 PBRM1 CDC6

3.14e-04139203GO:0051983
GeneOntologyBiologicalProcessnegative regulation of cell cycle process

CDK5RAP2 FGFR3 FGFR2 CDC6

3.62e-04362204GO:0010948
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

FGFR2 PBRM1

4.92e-0434202GO:0060977
GeneOntologyBiologicalProcessregulation of nuclear division

CDK5RAP2 FGFR3 FGFR2

5.85e-04172203GO:0051783
GeneOntologyBiologicalProcessendochondral bone growth

FGFR3 FGFR2

6.48e-0439202GO:0003416
GeneOntologyBiologicalProcessregulation of lipase activity

FGFR3 FGFR2

7.16e-0441202GO:0060191
GeneOntologyBiologicalProcesslens fiber cell differentiation

FGFR3 FGFR2

8.25e-0444202GO:0070306
GeneOntologyBiologicalProcessbone growth

FGFR3 FGFR2

8.62e-0445202GO:0098868
GeneOntologyBiologicalProcessnegative regulation of cell cycle

CDK5RAP2 FGFR3 FGFR2 CDC6

9.20e-04464204GO:0045786
GeneOntologyBiologicalProcessbiomineral tissue development

STIM1 FGFR3 FGFR2

9.46e-04203203GO:0031214
GeneOntologyBiologicalProcessregulation of cell cycle process

CDK5RAP2 FGFR3 FGFR2 PBRM1 CDC6

1.06e-03845205GO:0010564
GeneOntologyBiologicalProcessdigestive tract morphogenesis

FGFR3 FGFR2

1.48e-0359202GO:0048546
GeneOntologyBiologicalProcesslung epithelium development

FGFR3 FGFR2

1.58e-0361202GO:0060428
GeneOntologyBiologicalProcessregulation of epidermal cell differentiation

ABCA12 FGFR3

1.68e-0363202GO:0045604
GeneOntologyBiologicalProcesssister chromatid segregation

CDK5RAP2 PBRM1 CDC6

1.80e-03254203GO:0000819
GeneOntologyBiologicalProcesscell cycle process

CDK5RAP2 FGFR3 FGFR2 PBRM1 SEPTIN7 CDC6

1.90e-031441206GO:0022402
GeneOntologyBiologicalProcessregulation of chromosome organization

CDK5RAP2 PBRM1 CDC6

2.06e-03266203GO:0033044
GeneOntologyBiologicalProcessepithelial cell development

ABCA12 FGFR3 FGFR2

2.12e-03269203GO:0002064
GeneOntologyBiologicalProcesslung development

ABCA12 FGFR3 FGFR2

2.12e-03269203GO:0030324
GeneOntologyBiologicalProcessregulation of epidermis development

ABCA12 FGFR3

2.13e-0371202GO:0045682
GeneOntologyBiologicalProcessrespiratory tube development

ABCA12 FGFR3 FGFR2

2.21e-03273203GO:0030323
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

ARID5A GATAD2B FGFR3 FGFR2 THAP11

2.80e-031053205GO:0000122
GeneOntologyBiologicalProcesscoronary vasculature development

FGFR2 PBRM1

2.90e-0383202GO:0060976
HumanPhenoDuplication of the distal phalanx of the hallux

FGFR3 FGFR2

2.54e-054112HP:0010084
HumanPhenoDuplication of distal phalanx of toe

FGFR3 FGFR2

2.54e-054112HP:0010193
HumanPhenoHypoplasia of the lacrimal punctum

FGFR3 FGFR2

2.54e-054112HP:0007892
HumanPhenoLacrimal gland aplasia

FGFR3 FGFR2

2.54e-054112HP:0007656
HumanPhenoShort middle phalanx of toe

FGFR3 FGFR2

4.22e-055112HP:0003795
HumanPhenoIncreased corneal thickness

FGFR3 FGFR2

4.22e-055112HP:0011487
HumanPhenoDecreased corneal sensation

FGFR3 FGFR2

4.22e-055112HP:0012155
HumanPhenoProximal radio-ulnar synostosis

FGFR3 FGFR2

6.33e-056112HP:0005037
HumanPhenoMixed hearing impairment

CDK5RAP2 FGFR3 FGFR2

7.09e-0540113HP:0000410
HumanPhenoProminent crus of helix

FGFR3 FGFR2

8.85e-057112HP:0009899
HumanPhenoAbsent lacrimal punctum

FGFR3 FGFR2

8.85e-057112HP:0001092
HumanPhenoAbnormal lacrimal punctum morphology

FGFR3 FGFR2

1.18e-048112HP:0011479
HumanPhenoCloverleaf skull

FGFR3 FGFR2

1.18e-048112HP:0002676
HumanPhenoLimbal stem cell deficiency

FGFR3 FGFR2

1.18e-048112HP:0032107
HumanPhenoCorneal erosion

ABCA12 FGFR3 FGFR2

1.23e-0448113HP:0200020
HumanPhenoPalmoplantar cutis laxa

FGFR3 FGFR2

1.51e-049112HP:0007517
HumanPhenoHypoplasia of the epiglottis

FGFR3 FGFR2

1.89e-0410112HP:0005349
HumanPhenoAbnormality of the middle phalanges of the toes

FGFR3 FGFR2

2.31e-0411112HP:0010183
HumanPhenoLacrimal duct aplasia

FGFR3 FGFR2

2.31e-0411112HP:0007925
HumanPhenoAplastic/hypoplastic lacrimal glands

FGFR3 FGFR2

2.31e-0411112HP:0008038
HumanPhenoAbnormal fibula morphology

FGFR3 FGFR2 AFF3

2.64e-0462113HP:0002991
HumanPhenoAbnormality of the distal phalanx of the hallux

FGFR3 FGFR2

2.77e-0412112HP:0010053
HumanPhenoOpen angle glaucoma

FGFR3 FGFR2

2.77e-0412112HP:0012108
HumanPhenoAplasia/Hypoplasia of the Epiglottis

FGFR3 FGFR2

3.26e-0413112HP:0010565
HumanPhenoAbnormal lacrimal gland morphology

FGFR3 FGFR2

3.26e-0413112HP:0011482
HumanPhenoExcessive wrinkling of palmar skin

FGFR3 FGFR2

3.26e-0413112HP:0007605
HumanPhenoAbnormality of the crus of the helix

FGFR3 FGFR2

3.80e-0414112HP:0009895
HumanPhenoDuplication of phalanx of hallux

FGFR3 FGFR2

3.80e-0414112HP:0010066
HumanPhenoParietal foramina

FGFR3 FGFR2

3.80e-0414112HP:0002697
HumanPhenoDuplication of phalanx of toe

FGFR3 FGFR2

4.38e-0415112HP:0010181
HumanPhenoRecurrent corneal erosions

FGFR3 FGFR2

4.38e-0415112HP:0000495
HumanPhenoNarrow internal auditory canal

FGFR3 FGFR2

5.00e-0416112HP:0011386
HumanPhenoAbnormality of cartilage of external ear

FGFR3 FGFR2

6.37e-0418112HP:3000022
HumanPhenoAlacrima

FGFR3 FGFR2

6.37e-0418112HP:0000522
HumanPhenoUpper airway obstruction

FGFR3 FGFR2

6.37e-0418112HP:0002781
HumanPhenoLacrimal duct stenosis

FGFR3 FGFR2

7.11e-0419112HP:0007678
HumanPhenoUlnar bowing

FGFR3 FGFR2

7.89e-0420112HP:0003031
HumanPhenoKeratitis

ABCA12 FGFR3 FGFR2

7.94e-0490113HP:0000491
HumanPhenoAbnormality of the internal auditory canal

FGFR3 FGFR2

9.57e-0422112HP:0011384
HumanPhenoCorneal ulceration

FGFR3 FGFR2

9.57e-0422112HP:0012804
HumanPhenoAbnormality of cartilage morphology

FGFR3 FGFR2

1.05e-0323112HP:0410007
HumanPhenoAbnormal epiglottis morphology

FGFR3 FGFR2

1.05e-0323112HP:0005483
HumanPhenoTooth malposition

CDK5RAP2 GATAD2B FGFR3 FGFR2 AFF3

1.11e-03418115HP:0000692
HumanPhenoCorneal neovascularization

FGFR3 FGFR2

1.24e-0325112HP:0011496
HumanPhenoTarsal synostosis

FGFR3 FGFR2

1.34e-0326112HP:0008368
HumanPhenoAbnormal salivary gland morphology

FGFR3 FGFR2

1.34e-0326112HP:0010286
HumanPhenoEpiphora

FGFR3 FGFR2

1.44e-0327112HP:0009926
HumanPhenoDecreased lacrimation

FGFR3 FGFR2

1.44e-0327112HP:0000633
HumanPhenoBroad distal phalanx of finger

GATAD2B FGFR2

1.44e-0327112HP:0009836
HumanPhenoChoanal stenosis

FGFR3 FGFR2

1.55e-0328112HP:0000452
HumanPhenoAbnormal clavicle morphology

FGFR3 FGFR2 CDC6

1.66e-03116113HP:0000889
HumanPhenoAbnormality of the distal phalanges of the toes

FGFR3 FGFR2

1.67e-0329112HP:0010182
HumanPhenoAbnormal parietal bone morphology

FGFR3 FGFR2

1.67e-0329112HP:0002696
HumanPhenoPreaxial foot polydactyly

FGFR3 FGFR2

1.78e-0330112HP:0001841
HumanPhenoSynostosis involving bones of the feet

FGFR3 FGFR2

2.03e-0332112HP:0009140
HumanPhenoSynostosis involving bones of the lower limbs

FGFR3 FGFR2

2.03e-0332112HP:0009138
HumanPhenoCoronal craniosynostosis

FGFR3 FGFR2

2.03e-0332112HP:0004440
HumanPhenoAbnormality of the dentition

STIM1 ABCA12 CDK5RAP2 GATAD2B FGFR3 FGFR2 AFF3

2.08e-031030117HP:0000164
HumanPhenoAbnormality of the elbow

FGFR3 FGFR2 AFF3 CDC6

2.23e-03282114HP:0009811
HumanPhenoAnterior bulging of the globe

ABCA12 CDK5RAP2 FGFR3 FGFR2

2.25e-03283114HP:0000644
HumanPhenoProptosis

ABCA12 CDK5RAP2 FGFR3 FGFR2

2.25e-03283114HP:0000520
HumanPhenoHypoplasia of the maxilla

FGFR3 FGFR2 CDC6

2.31e-03130113HP:0000327
HumanPhenoAbnormal corneal epithelium morphology

ABCA12 FGFR3 FGFR2

2.41e-03132113HP:0011495
HumanPhenoMesomelia

FGFR3 AFF3

2.43e-0335112HP:0003027
HumanPhenoAplasia/Hypoplasia of the maxilla

FGFR3 FGFR2 CDC6

2.46e-03133113HP:0009117
HumanPhenoBlepharospasm

FGFR3 FGFR2

2.57e-0336112HP:0000643
HumanPhenoBowed forearm bones

FGFR3 FGFR2

2.57e-0336112HP:0003956
HumanPhenoNasolacrimal duct obstruction

FGFR3 FGFR2

2.57e-0336112HP:0000579
MousePhenoabnormal cranial synchondrosis

FGFR3 FGFR2

2.34e-056182MP:0030443
MousePhenoenlarged brain ventricles

CDK5RAP2 FGFR2 AFF3 THAP11

4.04e-05156184MP:0011380
MousePhenoabnormal brain ventricle size

CDK5RAP2 FGFR2 AFF3 THAP11

4.92e-05164184MP:0013229
MousePhenodecreased bone stiffness

STIM1 FGFR3

5.61e-059182MP:0013639
MousePhenoabnormal long bone epiphyseal ossification zone morphology

FGFR3 FGFR2

5.61e-059182MP:0006399
MousePhenoabnormal cranial cartilage development

FGFR3 FGFR2

5.61e-059182MP:0030467
MousePhenoshort basicranium

FGFR3 FGFR2

7.00e-0510182MP:0030420
MousePhenoabnormal coronal suture morphology

FGFR3 FGFR2

1.21e-0413182MP:0003840
MousePhenoabnormal bone stiffness

STIM1 FGFR3

1.21e-0413182MP:0013636
MousePhenopremature cranial suture closure

FGFR3 FGFR2

1.41e-0414182MP:0000081
MousePhenopremature intramembranous bone ossification

FGFR3 FGFR2

1.41e-0414182MP:0003418
MousePhenopremature craniofacial suture closure

FGFR3 FGFR2

1.41e-0414182MP:0030435
MousePhenoenlarged lateral ventricles

FGFR2 AFF3 THAP11

1.60e-0484183MP:0008535
MousePhenotranslucent skin

ABCA12 FGFR2

1.63e-0415182MP:0001201
MousePhenoenhanced osteoblast differentiation

FGFR3 FGFR2

1.63e-0415182MP:0011710
MousePhenoabnormal synchondrosis

FGFR3 FGFR2

1.86e-0416182MP:0004053
MousePhenomacrodontia

FGFR3 FGFR2

1.86e-0416182MP:0030091
MousePhenolong incisors

FGFR3 FGFR2

1.86e-0416182MP:0004831
MousePhenoperinatal lethality, complete penetrance

STIM1 ABCA12 GATAD2B FGFR3 FGFR2 THAP11

1.87e-04712186MP:0011089
MousePhenomidface hypoplasia

FGFR3 FGFR2

2.11e-0417182MP:0012085
MousePhenoincreased cranium width

FGFR3 FGFR2

2.64e-0419182MP:0000441
MousePhenoface hypoplasia

FGFR3 FGFR2

2.64e-0419182MP:0030065
MousePhenothin cerebral cortex

CDK5RAP2 GATAD2B THAP11

2.68e-04100183MP:0006254
MousePhenoabnormal snout morphology

GATAD2B FGFR3 FGFR2 AFF3

2.79e-04257184MP:0000443
MousePhenoabnormal vertebral column morphology

STIM1 CDK5RAP2 FGFR3 FGFR2 AFF3 THAP11

3.23e-04787186MP:0004703
MousePhenoabnormal incisor morphology

FGFR3 FGFR2 AFF3

3.55e-04110183MP:0005358
MousePhenodecreased cranium length

FGFR3 FGFR2

3.56e-0422182MP:0011862
MousePhenoabnormal brain ventricle morphology

CDK5RAP2 FGFR2 AFF3 THAP11

4.19e-04286184MP:0000822
MousePhenopremature bone ossification

FGFR3 FGFR2

5.00e-0426182MP:0003416
MousePhenosmall frontal bone

FGFR3 FGFR2

5.00e-0426182MP:0004377
MousePhenosmall parietal bone

FGFR3 FGFR2

5.39e-0427182MP:0004418
MousePhenodelayed bone ossification

FGFR3 FGFR2 AFF3

5.41e-04127183MP:0000060
MousePhenoabnormal corpus callosum morphology

GATAD2B FGFR2 AFF3

5.66e-04129183MP:0000780
MousePhenoabnormal palatine bone horizontal plate morphology

FGFR3 FGFR2

5.80e-0428182MP:0004537
MousePhenoabnormal midface morphology

FGFR3 FGFR2

5.80e-0428182MP:0030095
MousePhenoabnormal dorsal telencephalic commissure morphology

GATAD2B FGFR2 AFF3

6.05e-04132183MP:0008219
MousePhenoocular hypertelorism

FGFR3 FGFR2

6.23e-0429182MP:0001300
MousePhenolethality during fetal growth through weaning, complete penetrance

STIM1 ABCA12 GATAD2B FGFR3 FGFR2 PBRM1 THAP11

6.48e-041269187MP:0011111
MousePhenoabnormal cerebral hemisphere morphology

CDK5RAP2 GATAD2B FGFR2 AFF3 THAP11

7.64e-04599185MP:0008540
MousePhenoabnormal presphenoid bone morphology

FGFR3 FGFR2

8.08e-0433182MP:0004448
MousePhenothin epidermis

ABCA12 FGFR2

8.08e-0433182MP:0001218
MousePhenodecreased cranium height

FGFR3 FGFR2

8.08e-0433182MP:0008525
MousePhenoabnormal sternum ossification

FGFR3 FGFR2

1.02e-0337182MP:0008277
MousePhenoabnormal epidermis stratum basale morphology

ABCA12 FGFR2

1.02e-0337182MP:0001231
MousePhenosmall face

FGFR3 FGFR2

1.02e-0337182MP:0030064
MousePhenocraniofacial phenotype

ABCA12 CDK5RAP2 GATAD2B FGFR3 FGFR2 AFF3 THAP11

1.04e-031372187MP:0005382
MousePhenoabnormal craniofacial morphology

ABCA12 CDK5RAP2 GATAD2B FGFR3 FGFR2 AFF3 THAP11

1.04e-031372187MP:0000428
MousePhenodecreased bone strength

STIM1 FGFR3

1.07e-0338182MP:0004991
MousePhenoabnormal brain commissure morphology

GATAD2B FGFR2 AFF3

1.08e-03161183MP:0002199
MousePhenoabnormal lateral ventricle morphology

FGFR2 AFF3 THAP11

1.14e-03164183MP:0000823
MousePhenorespiratory failure

STIM1 FGFR2 THAP11

1.16e-03165183MP:0001953
MousePhenoabnormal embryonic/fetal subventricular zone morphology

CDK5RAP2 GATAD2B

1.25e-0341182MP:0004274
MousePhenodecreased respiration

STIM1 FGFR2 THAP11

1.26e-03170183MP:0014274
MousePhenodecreased width of hypertrophic chondrocyte zone

FGFR3 FGFR2

1.31e-0342182MP:0003409
MousePhenoabnormal face size

FGFR3 FGFR2

1.31e-0342182MP:0030063
MousePhenoabnormal brain ventricular system morphology

CDK5RAP2 FGFR2 AFF3 THAP11

1.38e-03393184MP:0002200
MousePhenoimpaired lung alveolus development

FGFR3 FGFR2

1.43e-0344182MP:0006027
MousePhenodecreased osteoblast cell number

FGFR3 FGFR2

1.50e-0345182MP:0004989
MousePhenoabnormal hyaline cartilage morphology

FGFR3 FGFR2

1.57e-0346182MP:0006429
MousePhenoabnormal palatine bone morphology

FGFR3 FGFR2

1.57e-0346182MP:0005249
MousePhenomalocclusion

FGFR3 FGFR2

1.64e-0347182MP:0000120
MousePhenoabnormal nervous system tract morphology

GATAD2B FGFR2 AFF3

1.71e-03189183MP:0000778
MousePhenoabnormal lung alveolus development

FGFR3 FGFR2

1.85e-0350182MP:0010995
MousePhenoabnormal cranial cartilage morphology

FGFR3 FGFR2

1.85e-0350182MP:0030464
MousePhenoabnormal fibula morphology

FGFR3 AFF3

1.92e-0351182MP:0002187
MousePhenoabnormal palate bone morphology

FGFR3 FGFR2

1.92e-0351182MP:0009891
MousePhenomisaligned teeth

FGFR3 FGFR2

2.00e-0352182MP:0030540
MousePhenoabnormal head morphology

ABCA12 CDK5RAP2 GATAD2B FGFR3 FGFR2 AFF3

2.09e-031120186MP:0000432
MousePhenoabnormal brain white matter morphology

GATAD2B FGFR2 AFF3

2.19e-03206183MP:0008026
MousePhenoperinatal lethality

STIM1 ABCA12 GATAD2B FGFR3 FGFR2 THAP11

2.19e-031130186MP:0002081
DomainFGF_rcpt_fam

FGFR3 FGFR2

6.53e-064202IPR016248
DomainBromodomain_CS

BAZ2B PBRM1

3.49e-0426202IPR018359
DomainBROMODOMAIN_1

BAZ2B PBRM1

7.09e-0437202PS00633
DomainBromodomain

BAZ2B PBRM1

7.48e-0438202PF00439
DomainBROMODOMAIN_2

BAZ2B PBRM1

8.71e-0441202PS50014
DomainBROMO

BAZ2B PBRM1

9.14e-0442202SM00297
DomainBromodomain

BAZ2B PBRM1

9.14e-0442202IPR001487
Domain-

BAZ2B PBRM1

9.14e-04422021.20.920.10
DomainTyrKc

FGFR3 FGFR2

3.95e-0388202SM00219
DomainTyr_kinase_cat_dom

FGFR3 FGFR2

3.95e-0388202IPR020635
DomainPROTEIN_KINASE_TYR

FGFR3 FGFR2

4.77e-0397202PS00109
DomainTyr_kinase_AS

FGFR3 FGFR2

4.77e-0397202IPR008266
DomainPkinase_Tyr

FGFR3 FGFR2

8.29e-03129202PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

FGFR3 FGFR2

9.44e-03138202IPR001245
DomainAAA+_ATPase

ABCA12 CDC6

1.02e-02144202IPR003593
DomainAAA

ABCA12 CDC6

1.02e-02144202SM00382
DomainI-set

FGFR3 FGFR2

1.73e-02190202PF07679
DomainIg_I-set

FGFR3 FGFR2

1.73e-02190202IPR013098
Domain-

PREX2 CDC6

2.24e-022182021.10.10.10
DomainIg_sub2

FGFR3 FGFR2

2.58e-02235202IPR003598
DomainIGc2

FGFR3 FGFR2

2.58e-02235202SM00408
DomainWHTH_DNA-bd_dom

PREX2 CDC6

2.72e-02242202IPR011991
PathwayWP_FGF23_SIGNALING_IN_HYPOPHOSPHATEMIC_RICKETS_AND_RELATED_DISORDERS

FGFR3 FGFR2

2.64e-0423152M39862
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

PREX2 GATAD2B FGFR3 FGFR2

2.68e-04313154M27867
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

FGFR3 FGFR2

3.13e-0425152M47934
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY

FGFR3 FGFR2

4.83e-0431152M47396
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY

FGFR3 FGFR2

6.16e-0435152M47379
PathwayREACTOME_IRS_MEDIATED_SIGNALLING

FGFR3 FGFR2

1.16e-0348152M26916
PathwayWP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY

FGFR3 FGFR2

1.26e-0350152M48087
PathwayREACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R

FGFR3 FGFR2

1.46e-0354152M27168
PathwayREACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE

FGFR3 FGFR2

1.46e-0354152M620
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

FGFR3 FGFR2

1.52e-0355152M47952
PathwayPID_FGF_PATHWAY

FGFR3 FGFR2

1.52e-0355152M276
PathwayWP_ENDOMETRIAL_CANCER

FGFR3 FGFR2

1.99e-0363152M39623
PathwayREACTOME_SIGNALING_BY_FGFR_IN_DISEASE

FGFR3 FGFR2

1.99e-0363152M635
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

PREX2 GATAD2B FGFR3

2.19e-03252153MM15585
Pubmed

Fibroblast growth factor receptor 3 is a negative regulator of bone growth.

FGFR3 FGFR2

3.82e-0722228601314
Pubmed

Activation of FGF receptors by mutations in the transmembrane domain.

FGFR3 FGFR2

3.82e-0722229136983
Pubmed

Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.

FGFR3 FGFR2

3.82e-07222211325814
Pubmed

Novel targetable FGFR2 and FGFR3 alterations in glioblastoma associate with aggressive phenotype and distinct gene expression programs.

FGFR3 FGFR2

3.82e-07222233853673
Pubmed

Prognostic impact of FGFR2/3 alterations in patients with biliary tract cancers receiving systemic chemotherapy: the BITCOIN study.

FGFR3 FGFR2

3.82e-07222235303508
Pubmed

Germline mutations in FGF receptors and medulloblastomas.

FGFR3 FGFR2

3.82e-07222223325524
Pubmed

Early mandibular morphological differences in patients with FGFR2 and FGFR3-related syndromic craniosynostoses: A 3D comparative study.

FGFR3 FGFR2

3.82e-07222232822871
Pubmed

Deficits Associated With Loss of STIM1 in Purkinje Neurons Including Motor Coordination Can Be Rescued by Loss of Septin 7.

STIM1 SEPTIN7

3.82e-07222234993201
Pubmed

Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma.

FGFR3 FGFR2

3.82e-07222223786770
Pubmed

Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

FGFR3 FGFR2

3.82e-07222221152424
Pubmed

Transient Redirection of SVZ Stem Cells to Oligodendrogenesis by FGFR3 Activation Promotes Remyelination.

FGFR3 FGFR2

1.15e-06322231189094
Pubmed

Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3.

FGFR3 FGFR2

1.15e-06322230202094
Pubmed

Mutations in different components of FGF signaling in LADD syndrome.

FGFR3 FGFR2

1.15e-06322216501574
Pubmed

FGFR Craniosynostosis Syndromes Overview

FGFR3 FGFR2

1.15e-06322220301628
Pubmed

Isolation of the complementary DNA encoding a mouse heparin-binding growth factor receptor with the use of a unique kinase insert sequence.

FGFR3 FGFR2

1.15e-0632228382556
Pubmed

Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.

FGFR3 FGFR2

1.15e-06322214732692
Pubmed

Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes.

FGFR3 FGFR2

1.15e-06322231830366
Pubmed

Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway.

FGFR3 FGFR2

1.15e-06322212032146
Pubmed

Fibroblast Growth Factor (FGF-2) and Its Receptors FGFR-2 and FGFR-3 May Be Putative Biomarkers of Malignant Transformation of Potentially Malignant Oral Lesions into Oral Squamous Cell Carcinoma.

FGFR3 FGFR2

1.15e-06322226465941
Pubmed

Expression of fibroblast growth factor receptor1, -2c, and -3c transcripts in mouse molars after tooth eruption.

FGFR3 FGFR2

1.15e-06322233433858
Pubmed

Fibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia.

FGFR3 FGFR2

1.15e-06322230755670
Pubmed

Expression of fibroblast growth factor receptors (FGFR1, FGFR2, FGFR3) in the developing head and face.

FGFR3 FGFR2

1.15e-0632229286594
Pubmed

Tracheal cartilaginous sleeves in children with syndromic craniosynostosis.

FGFR3 FGFR2

1.15e-06322227228464
Pubmed

FGFR1/3 tyrosine kinase fusions define a unique molecular subtype of non-small cell lung cancer.

FGFR3 FGFR2

1.15e-06322224850843
Pubmed

Fibroblast growth factor (FGF) 3 from Xenopus laevis (XFGF3) binds with high affinity to FGF receptor 2.

FGFR3 FGFR2

1.15e-0632227896824
Pubmed

Identification of fibroblast growth factor 9 (FGF9) as a high affinity, heparin dependent ligand for FGF receptors 3 and 2 but not for FGF receptors 1 and 4.

FGFR3 FGFR2

1.15e-0632228619928
Pubmed

Differential roles of fibroblast growth factor receptors (FGFR) 1, 2 and 3 in the regulation of S115 breast cancer cell growth.

FGFR3 FGFR2

1.15e-06322223185502
Pubmed

FGF-FGFR Mediates the Activity-Dependent Dendritogenesis of Layer IV Neurons during Barrel Formation.

FGFR3 FGFR2

1.15e-06322229097598
Pubmed

Fibroblast growth factor receptors in in vitro and in vivo chondrogenesis: relating tissue engineering using adult mesenchymal stem cells to embryonic development.

FGFR3 FGFR2

1.15e-06322219728793
Pubmed

Enriched Environment Promotes Adult Hippocampal Neurogenesis through FGFRs.

FGFR3 FGFR2

1.15e-06322233637561
Pubmed

Fibroblast growth factor receptor (FGFR) gene amplifications are rare events in bladder cancer.

FGFR3 FGFR2

1.15e-06322224898159
Pubmed

Genetic heterogeneity of Saethre-Chotzen syndrome, due to TWIST and FGFR mutations.

FGFR3 FGFR2

1.15e-0632229585583
Pubmed

FGFR mutations and plagiocephaly.

FGFR3 FGFR2

1.15e-06322218216705
Pubmed

Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis.

FGFR3 FGFR2

2.29e-06422210704861
Pubmed

Somatic FGFR and TWIST mutations are not a common cause of isolated nonsyndromic single suture craniosynostosis.

FGFR3 FGFR2

2.29e-06422217414280
Pubmed

Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.

FGFR3 FGFR2

2.29e-0642229212826
Pubmed

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.

FGFR3 FGFR2

2.29e-06422227154171
Pubmed

Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma.

FGFR3 FGFR2

2.29e-06422223393200
Pubmed

Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.

FGFR3 FGFR2

2.29e-0642229664689
Pubmed

Isolated sagittal and coronal craniosynostosis associated with TWIST box mutations.

FGFR3 FGFR2

2.29e-06422217343269
Pubmed

Astrocyte activation is suppressed in both normal and injured brain by FGF signaling.

FGFR3 FGFR2

2.29e-06422225002516
Pubmed

Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.

FGFR3 FGFR2

2.29e-06422212373339
Pubmed

FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.

FGFR3 FGFR2

2.29e-06422236142417
Pubmed

Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.

FGFR3 FGFR2

2.29e-06422211759058
Pubmed

Lens fiber cell differentiation occurs independently of fibroblast growth factor receptor signaling in the absence of Pten.

FGFR3 FGFR2

2.29e-06422232858001
Pubmed

The FGF system has a key role in regulating vascular integrity.

FGFR3 FGFR2

2.29e-06422218776942
Pubmed

The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation.

FGFR3 FGFR2

2.29e-06422215105428
Pubmed

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.

FGFR3 FGFR2

2.29e-06422217304337
Pubmed

Expression of basic fibroblast growth factor and its receptors in human ovarian follicles from adults and fetuses.

FGFR3 FGFR2

2.29e-06422216210019
Pubmed

Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.

FGFR3 FGFR2

2.29e-06422212644244
Pubmed

Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.

FGFR3 FGFR2

3.82e-06522227206683
Pubmed

Nectin-1 binds and signals through the fibroblast growth factor receptor.

FGFR3 FGFR2

3.82e-06522222955284
Pubmed

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.

FGFR3 FGFR2

3.82e-06522215987787
Pubmed

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

FGFR3 FGFR2

3.82e-06522228094278
Pubmed

Expression and biological activity of mouse fibroblast growth factor-9.

FGFR3 FGFR2

3.82e-0652228576175
Pubmed

The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.

FGFR3 FGFR2

3.82e-06522227078042
Pubmed

Craniosynostosis: genes and mechanisms.

FGFR3 FGFR2

3.82e-0652229300656
Pubmed

Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1.

FGFR3 FGFR2

3.82e-06522219696444
Pubmed

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.

FGFR3 FGFR2

3.82e-06522216091423
Pubmed

FGF-dependent regulation of VEGF receptor 2 expression in mice.

FGFR3 FGFR2

3.82e-06522221633168
Pubmed

FGF21 signalling pathway and metabolic traits - genetic association analysis.

FGFR3 FGFR2

3.82e-06522220717167
Pubmed

Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.

FGFR3 FGFR2

3.82e-0652229771645
Pubmed

Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.

FGFR3 FGFR2

3.82e-0652229013630
Pubmed

The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.

FGFR3 FGFR2

3.82e-06522211566361
Pubmed

Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.

FGFR3 FGFR2

5.72e-06622219232523
Pubmed

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.

FGFR3 FGFR2

5.72e-06622229720668
Pubmed

Distinct genetic loci control development of benign and malignant skin tumours in mice.

FGFR3 FGFR2

5.72e-0662227670492
Pubmed

Gyrification of the cerebral cortex requires FGF signaling in the mammalian brain.

FGFR3 FGFR2

5.72e-06622229132503
Pubmed

Discrete domains of gene expression in germinal layers distinguish the development of gyrencephaly.

FGFR3 FGFR2

5.72e-06622225916825
Pubmed

Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.

FGFR3 FGFR2

5.72e-06622210572038
Pubmed

Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb.

FGFR3 FGFR2

5.72e-06622238056728
Pubmed

Somatic mutation of epidermal growth factor receptor in a small subset of cutaneous squamous cell carcinoma.

FGFR3 FGFR2

5.72e-06622219812598
Pubmed

The complex morphology of reactive astrocytes controlled by fibroblast growth factor signaling.

FGFR3 FGFR2

5.72e-06622224796693
Pubmed

FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.

FGFR3 FGFR2

5.72e-0662229010207
Pubmed

Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.

FGFR3 FGFR2

5.72e-06622216365308
Pubmed

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1.

FGFR3 FGFR2

5.72e-06622224026051
Pubmed

Regulation of fibroblast growth factor-23 signaling by klotho.

FGFR3 FGFR2

5.72e-06622216436388
Pubmed

FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code.

FGFR3 FGFR2

8.01e-06722216772167
Pubmed

Fibroblast growth factor signaling regulates Dach1 expression during skeletal development.

FGFR3 FGFR2

8.01e-06722212203718
Pubmed

Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells.

FGFR3 FGFR2

8.01e-0672228959336
Pubmed

FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells.

FGFR3 FGFR2

8.01e-06722217192470
Pubmed

Expression patterns of FGF receptors in the developing mammalian cochlea.

FGFR3 FGFR2

8.01e-06722220131355
Pubmed

Fibroblast Growth Factor 2 Modulates Hypothalamic Pituitary Axis Activity and Anxiety Behavior Through Glucocorticoid Receptors.

FGFR3 FGFR2

8.01e-06722227133954
Pubmed

Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula.

FGFR3 FGFR2

1.07e-05822228389228
Pubmed

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

FGFR3 FGFR2

1.07e-05822217623664
Pubmed

Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones.

FGFR3 FGFR2

1.07e-05822219218784
Pubmed

Expression of FGF receptors 1, 2, 3 in the embryonic and postnatal mouse brain compared with Pdgfralpha, Olig2 and Plp/dm20: implications for oligodendrocyte development.

FGFR3 FGFR2

1.07e-05822212966207
Pubmed

FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors.

FGFR3 FGFR2

1.07e-05822214602678
Pubmed

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.

FGFR3 FGFR2

1.07e-05822218187602
Pubmed

Molecular mechanisms in calvarial bone and suture development, and their relation to craniosynostosis.

FGFR3 FGFR2

1.07e-05822212737212
Pubmed

Syndecan-4 dependent FGF stimulation of mouse vibrissae growth.

FGFR3 FGFR2

1.07e-05822216989989
Pubmed

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

FGFR3 FGFR2 PBRM1

1.22e-057122328319113
Pubmed

FGF Signaling Directs the Cell Fate Switch from Neurons to Astrocytes in the Developing Mouse Cerebral Cortex.

FGFR3 FGFR2

1.37e-05922231175212
Pubmed

The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear.

FGFR3 FGFR2

1.37e-05922211335076
Pubmed

Autocrine and paracrine mechanisms regulating primordial germ cell proliferation.

FGFR3 FGFR2

1.37e-05922215039943
Pubmed

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.

FGFR3 FGFR2

1.37e-05922215229180
Pubmed

Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse.

FGFR3 FGFR2

1.37e-05922215830353
Pubmed

Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development.

FGFR3 FGFR2

1.37e-05922231613912
Pubmed

FGF9 can induce endochondral ossification in cranial mesenchyme.

FGFR3 FGFR2

1.37e-05922216504022
Pubmed

Integration of FGF and TWIST in calvarial bone and suture development.

FGFR3 FGFR2

1.37e-05922210751173
InteractionFGF6 interactions

FGFR3 FGFR2

2.38e-057222int:FGF6
InteractionFGF18 interactions

FGFR3 FGFR2

2.38e-057222int:FGF18
InteractionFGF5 interactions

FGFR3 FGFR2

3.17e-058222int:FGF5
InteractionFGF23 interactions

FGFR3 FGFR2

3.17e-058222int:FGF23
InteractionCRLF2 interactions

STIM1 FGFR3 FGFR2

3.90e-0561223int:CRLF2
InteractionDENND10P1 interactions

DENND10P1 DENND10

4.08e-059222int:DENND10P1
InteractionCEP192 interactions

CDK5RAP2 FGFR3 FGFR2 BICD1

5.11e-05192224int:CEP192
InteractionKLB interactions

FGFR3 FGFR2

7.46e-0512222int:KLB
InteractionKL interactions

FGFR3 FGFR2

1.03e-0414222int:KL
InteractionSEC24B interactions

STIM1 FGFR3 FGFR2 BICD1

1.21e-04240224int:SEC24B
InteractionFGF7 interactions

FGFR3 FGFR2

1.35e-0416222int:FGF7
InteractionFGF9 interactions

FGFR3 FGFR2

1.35e-0416222int:FGF9
InteractionNCKAP5L interactions

CDK5RAP2 BICD1 THAP11

2.03e-04106223int:NCKAP5L
InteractionCENPE interactions

PBRM1 BICD1 SEPTIN7

2.03e-04106223int:CENPE
InteractionNECTIN1 interactions

FGFR3 FGFR2

2.59e-0422222int:NECTIN1
CytobandEnsembl 112 genes in cytogenetic band chr2q11

ARID5A AFF3

2.44e-03153222chr2q11
CytobandEnsembl 112 genes in cytogenetic band chr16q22

PMFBP1 THAP11

3.46e-03183222chr16q22
CytobandEnsembl 112 genes in cytogenetic band chr10q26

FGFR2 DENND10

4.40e-03207222chr10q26
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FGFR3 FGFR2

4.92e-0440152321
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FGFR3 FGFR2

7.67e-03161152593
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PREX2 FGFR3 FGFR2

4.90e-0515321395b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PREX2 FGFR3 FGFR2

4.90e-05153213b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PREX2 FGFR3 FGFR2

4.90e-051532133ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFR3 FGFR2 CDC6

5.81e-051622133a1cbfed5a063131d49e3c1584f62b12660ecb36
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFR3 FGFR2 CDC6

5.81e-0516221304b3c38bb27fa369a9ac5b60883f8b058abc5180
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK5RAP2 FGFR3 CDC6

6.94e-051722132b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

8.61e-05185213b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

8.75e-0518621373cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

8.89e-0518721397e520705491c8f52a32025311a9fa7b9176979a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

8.89e-05187213dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST3 PREX2 FGFR3

8.89e-05187213daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST3 PREX2 FGFR3

8.89e-051872135b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

8.89e-05187213ae90c263f80c36a410150d499e268d198944a3d9
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.03e-05188213505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PREX2 AFF3 BICD1

9.03e-05188213117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.18e-0518921342ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.18e-05189213784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.18e-0518921337ecbd73408d462b47d7e5611f203143e08a2689
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.32e-0519021307f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.32e-051902132de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.32e-05190213ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIM1 BAZ2B SEPTIN7

9.47e-0519121360c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.47e-051912132b056cbe2e82e056e1f798974999378460eb1d16
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.47e-05191213f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIM1 BAZ2B SEPTIN7

9.47e-0519121309db184cb90fe282a14474d7217068c58092c6f8
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PREX2 FGFR3 FGFR2

9.47e-05191213a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIM1 BAZ2B SEPTIN7

9.47e-05191213973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAZ2B PREX2 BICD1

9.91e-051942130b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PREX2 AFF3 BICD1

9.91e-0519421371ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARID5A PREX2 AFF3

9.91e-05194213a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

BAZ2B FGFR2 BICD1

1.02e-0419621338da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

BAZ2B FGFR2 BICD1

1.02e-04196213721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BEST3 AFF3 SEPTIN7

1.04e-041972137290f05d0b8465637420119941bcbf2fae44a7e4
ToppCell10x5'v1-week_14-16-Lymphocytic_B|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BEST3 AFF3 SEPTIN7

1.04e-0419721331dfd9842410b5c629f39b5130233995dceb0aef
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BEST3 AFF3 SEPTIN7

1.04e-04197213106b0f9a0425facc634feb7498c9ba2c55edfbf8
ToppCellmedial-2-Epithelial-Basal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA12 FGFR3 FGFR2

1.07e-0419921310af93596cc6d5da4cf5052707ff5f7fc347dc84
ToppCellmedial-Epithelial-Basal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA12 FGFR3 FGFR2

1.07e-04199213fa7584e3cc0f8cbdd6a76c6a0faee26b0922c4ae
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

BAZ2B ZFAND3 AFF3

1.07e-0419921394b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellmedial-Epithelial-Basal-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA12 FGFR3 FGFR2

1.07e-04199213fc37f8868417308fb4410684d0d1e506cec30f35
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pre_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BEST3 AFF3 SEPTIN7

1.07e-04199213dadee9fc6ce4f4bdb19d29326889316443dda0cb
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

PREX2 FGFR3 FGFR2

1.08e-04200213e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCell10x3'2.3-week_14-16-Lymphocytic_B|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BEST3 AFF3 SEPTIN7

1.08e-0420021319a4213f180ac2d29625d140b602a93a74ab3fdd
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PREX2 FGFR3 FGFR2

1.08e-04200213d0812817ef99608994193787a62d39adeb2070ca
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BEST3 AFF3 SEPTIN7

1.08e-042002130fd9a8730b7dc461ddf4586899d363541e72d8ba
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PREX2 FGFR3 FGFR2

1.08e-04200213cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellB_cell_maturation-pre-B|World / Lineage and Cell class

BEST3 AFF3 CDC6

1.08e-04200213acb9ad7e3c05ec38e9700fb27b6eed8eaa565689
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a6-Slc17a7.Fezf2.3110035E14Rik_(Deep_layer_pyramidal_cells-Layer_5b)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA12 PMFBP1

5.20e-04722124f424d2d4e62f212881189f3e99cec22048438f0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a6-Slc17a7-Slc17a8.Fezf2.Slc17a8_(Deep_layer_pyramidal_cells-Layer_5b)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA12 PMFBP1

5.49e-0474212e6c8b8046948a205e996e585f983fd0af80d5491
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCA12 PMFBP1

7.75e-0488212fcc15c5c30517c63a835b28627c5f779d9bcd17e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCA12 PMFBP1

7.75e-04882127838c65160cf81c02b923fc34f566c0610c8d81b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA12 PMFBP1

9.03e-0495212ffbf3e362384c87b9db690ed39cd215e1f68375c
ToppCellLPS-IL1RA-Endothelial-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGFR3 PMFBP1

1.34e-03116212cf4e3c34570f57502ec524881d351ef8e47976d2
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGFR3 PMFBP1

1.60e-031272126b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ABCA12 FGFR3

1.70e-03131212ff4e618bd944f852bbd34438f740187aca82460f
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative|E16.5-samps / Age Group, Lineage, Cell class and subclass

CDK5RAP2 PMFBP1

1.83e-0313621296370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PMFBP1 SEPTIN7

1.97e-031412125ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGFR2 AFF3

2.05e-031442121b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BAZ2B BICD1

2.08e-03145212fd02d55755c35288a42ab08a82450b370aad35a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARID5A FGFR3

2.08e-031452122eebf2294c53f081d3b0169071388e477a195218
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Met|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCA12 SEPTIN7

2.08e-031452128abbc781f5f69f039617c29a5589d7b6950c2c40
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-regulatory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA12 THAP11

2.11e-031462127748277cf2f12e2930d4f5a22247ab9bc266a954
ToppCellBronchus_Control_(B.)-Immune-TX-TRAM-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

GATAD2B AFF3

2.14e-0314721250a855aa7f214c3be8ac46a22adf9bc9dd0285db
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCA12 PMFBP1

2.20e-03149212558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BEST3 ABCA12

2.20e-03149212c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BEST3 ABCA12

2.20e-03149212a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell(00)_Basal|World / shred by cell type and Timepoint

FGFR3 FGFR2

2.20e-0314921249e39206f37cee124ca4763c79425b805e50624b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L6_NP_ALM_Trh|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCA12 PMFBP1

2.20e-03149212fe9dff31a30dabd212d53d1295f9f13ff32cb217
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCA12 PMFBP1

2.22e-031502122ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGFR3 CDC6

2.25e-03151212c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PREX2 CDC6

2.37e-031552125d157478669b609e1f0f0a75afd0112571fc2c46
ToppCellP28-Epithelial-epithelial_progenitor_cell-epi_progenitor|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BEST3 FGFR2

2.37e-03155212be575a0096415705dba425002247289ff8f89474
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AFF3 BICD1

2.40e-03156212203ef22eb76bd2b829b027c30af0557080f4006c
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GATAD2B AFF3

2.40e-031562120f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GATAD2B AFF3

2.40e-03156212cb87f12443fdc5538b856f765fcbac9406044e10
ToppCellfrontal_cortex-Non-neuronal-astrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PREX2 FGFR3

2.43e-03157212803af734d7f775d294391e2b84e472a732e18cef
ToppCellPND07-28-samps-Lymphocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

BEST3 CDC6

2.43e-03157212105f2711d7bae3be36714954e103c61cf021f957
ToppCellPND07-28-samps-Lymphocyte-T_cells|PND07-28-samps / Age Group, Lineage, Cell class and subclass

BEST3 CDC6

2.43e-03157212f3b4cde52423246ae6fc4924cd1ee502cf6c009c
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PREX2 FGFR3

2.43e-031572129aa5304a9704da6dd4eda7d6940494b00e38b2e8
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK_CD56bright|Leuk-UTI / Disease, Lineage and Cell Type

ARID5A SEPTIN7

2.43e-03157212db0057741d06e212a9543cb4b011659b79efeafc
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

FGFR3 AFF3

2.43e-0315721231d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PREX2 FGFR3

2.43e-031572120551442ae14685d8fe5729e3960c6324b1e05e4d
ToppCellEntopeduncular|World / BrainAtlas - Mouse McCarroll V32

BAZ2B FGFR2

2.52e-03160212833763c8608de4ee6003b8fb682aa9c83d7dea9b
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ2B AFF3

2.52e-03160212237430af14830b38e58da8a4224036e5c6b71c5b
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PMFBP1 SEPTIN7

2.59e-0316221258da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PREX2 PMFBP1

2.59e-03162212a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

PREX2 FGFR3

2.65e-03164212519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARID5A AFF3

2.68e-031652128b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ARID5A AFF3

2.68e-03165212243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARID5A PREX2

2.71e-03166212ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARID5A CDC6

2.75e-03167212784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pro-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BEST3 AFF3

2.78e-03168212c833e3311af2582787d3ff2ad59d802fff865f8f
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

CDK5RAP2 BICD1

2.78e-0316821200646601548b0fee42ae16bfa5e93603bc7c5129
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFR3 FGFR2

2.78e-03168212100ab6d36592b61f4db9f8cb90c48afac016d679
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

ABCA12 FGFR3

2.78e-0316821248089fa2d4a0f31a72405717119b767a92571f01
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA12 CDC6

2.81e-03169212121768fc51fc3441ec725346a1bbe29e21d05971
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA12 FGFR2

2.81e-03169212aec97583b23112060437b619cb429dc32f29285f
ToppCelldroplet-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFR3 FGFR2

2.81e-0316921253690d6f9712b54aa99a0408aae930d64ae478e5
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID5A AFF3

2.84e-0317021253fd50c9a27d47662fbcbd7e9e9837f72ac448c5
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PREX2 BICD1

2.84e-0317021250c6c571591aa4b218caefe5778c570c809f567e
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR2 CDC6

2.84e-031702124ce81608111b9ee7cb974dad2c182f38db3dcd79
Drug3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea

FGFR3 FGFR2

5.34e-064222ctd:C568950
DrugPalifermin

FGFR3 FGFR2

1.33e-056222DB00039
Drug17-AAG; Up 200; 1uM; MCF7; HG-U133A

CDK5RAP2 FGFR2 BICD1 CDC6

3.12e-05191224381_UP
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A

CDK5RAP2 PMFBP1 PBRM1 BICD1

3.52e-051972246863_UP
DrugPD 166285

FGFR3 FGFR2

5.85e-0512222CID005311382
Drugcrisamicin A

FGFR3 FGFR2

6.91e-0513222CID000125855
Drugdifluoroboron

FGFR3 FGFR2 PBRM1

7.09e-0584223CID000139622
DiseaseIsolated coronal synostosis

FGFR3 FGFR2

4.36e-072202cv:CN043619
DiseaseLacrimoauriculodentodigital syndrome

FGFR3 FGFR2

1.31e-063202C0265269
DiseaseSaethre-Chotzen Syndrome

FGFR3 FGFR2

1.31e-063202C0175699
DiseaseCongenital hypoplasia of radius

FGFR3 FGFR2

1.31e-063202C0685381
DiseaseLevy-Hollister syndrome

FGFR3 FGFR2

1.31e-063202cv:C0265269
DiseaseTWIST1-related craniosynostosis

FGFR3 FGFR2

2.62e-064202cv:C4551902
DiseaseCongenital small ears

FGFR3 FGFR2 CDC6

2.79e-0641203C0152423
Diseasebone disease (implicated_via_orthology)

FGFR3 FGFR2

4.36e-065202DOID:0080001 (implicated_via_orthology)
DiseaseCraniosynostosis syndrome

FGFR3 FGFR2

9.15e-067202cv:C0010278
Diseasecraniosynostosis (is_implicated_in)

FGFR3 FGFR2

2.87e-0512202DOID:2340 (is_implicated_in)
DiseaseBrachycephaly

FGFR3 FGFR2

5.90e-0517202C0221356
DiseaseIntrahepatic Cholangiocarcinoma

FGFR2 PBRM1

1.19e-0424202C0345905
DiseaseExtrahepatic Cholangiocarcinoma

FGFR2 PBRM1

1.19e-0424202C3805278
DiseaseCholangiocarcinoma

FGFR2 PBRM1

1.40e-0426202C0206698
DiseaseCleft upper lip

FGFR3 FGFR2

3.19e-0439202C0008924
DiseaseCleft palate, isolated

FGFR3 FGFR2

3.70e-0442202C1837218
Diseasehigh grade glioma (implicated_via_orthology)

FGFR3 FGFR2

4.06e-0444202DOID:3070 (implicated_via_orthology)
Diseaseneuroimaging measurement

GATAD2B FGFR3 FGFR2 AFF3 BICD1

6.08e-041069205EFO_0004346

Protein segments in the cluster

PeptideGeneStartEntry
HMLKLAMDLKGKMPN

PRPF4B

896

Q13523
AVDEMHMSLPKMKKD

BEST3

321

Q8N1M1
MQEAKRMKHKADAMV

AFF3

981

P51826
AKEAMAMGKLHKEMG

DENND10P1

266

Q6NSW5
KAKEERRMDQMMPGK

ARID5A

181

Q03989
SGEKMAHMEKELQKM

BICD1

476

Q96G01
EKDLRLHEYMKMMGV

ABCA12

1091

Q86UK0
HMMLMKAMEARKKAE

BAZ2B

1011

Q9UIF8
EHDHRKRMGLKMLMM

CYC1

281

P08574
EMKKMHEGDLAMALV

CDK5RAP2

201

Q96SN8
LVSEMEMMKMIGKHK

FGFR2

531

P21802
KKPMDMEKIRSHMMA

PBRM1

701

Q86U86
RLKMEGHEAMERLKM

GATAD2B

31

Q8WXI9
KDMMRKLEKHMTAEK

CDC6

261

Q99741
DLVSEMEMMKMIGKH

FGFR3

521

P22607
AKEAMAMGKLHKEMG

DENND10

266

Q8TCE6
HENSFMKMLRSKMGK

POTED

86

Q86YR6
IMKDMMKLELDLHGL

PMFBP1

346

Q8TBY8
YSKEHMKKMMKDLEG

STIM1

236

Q13586
MKKMMKDLEGLHRAE

STIM1

241

Q13586
EERREHVAKMKKMEM

SEPTIN7

341

Q16181
DEEMEGSNMKHRLMK

PREX2

566

Q70Z35
HMGRGREEAIMKMVK

ZFAND3

196

Q9H8U3
MEVKMKEMKGSIRHL

THAP11

271

Q96EK4