Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.73e-06	12	157	4	GO:0017154
GeneOntologyMolecularFunction	acetylspermidine deacetylase activity	HDAC6 HDAC10	6.14e-05	2	157	2	GO:0047611
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA3 PLXNA4 PLXNA2 PLXNB1	2.18e-06	13	159	4	GO:0002116
Domain	Plexin_cytopl	PLXNA3 PLXNA4 PLXNA2 PLXNB1	5.57e-07	9	155	4	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNA4 PLXNA2 PLXNB1	5.57e-07	9	155	4	IPR013548
Domain	Plexin	PLXNA3 PLXNA4 PLXNA2 PLXNB1	5.57e-07	9	155	4	IPR031148
Domain	IPT	PLXNA3 PLXNA4 PLXNA2 PLXNB1	6.90e-05	27	155	4	SM00429
Domain	-	PLXNA3 TAF1C WDR27 WDFY4 HIRA PLXNA4 IFT122 DCAF4 PLXNA2 PLXNB1 NSMAF	1.08e-04	333	155	11	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	PLXNA3 TAF1C WDR27 WDFY4 HIRA PLXNA4 IFT122 DCAF4 PLXNA2 PLXNB1 NSMAF	1.14e-04	335	155	11	IPR015943
Domain	Semap_dom	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.21e-04	31	155	4	IPR001627
Domain	SEMA	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.21e-04	31	155	4	PS51004
Domain	TIG	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.21e-04	31	155	4	PF01833
Domain	Sema	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.21e-04	31	155	4	SM00630
Domain	Sema	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.21e-04	31	155	4	PF01403
Domain	IPT	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.37e-04	32	155	4	IPR002909
Domain	Plexin_repeat	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.37e-04	32	155	4	IPR002165
Domain	PSI	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.37e-04	32	155	4	PF01437
Domain	PSI	PLXNA3 PLXNA4 PLXNA2 PLXNB1	4.78e-04	44	155	4	IPR016201
Domain	PSI	PLXNA3 PLXNA4 PLXNA2 PLXNB1	5.68e-04	46	155	4	SM00423
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA3 PLXNA4 PLXNA2	3.65e-05	9	109	3	MM15030
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA3 PLXNA4 PLXNA2	1.54e-04	14	109	3	MM15029
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA3 PLXNA4 PLXNA2	1.54e-04	14	109	3	M7578
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA3 PLXNA4 PLXNA2	1.91e-04	15	109	3	MM15031
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA3 PLXNA4 PLXNA2	2.34e-04	16	109	3	M16498
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA3 PLXNA4 PLXNA2	2.34e-04	16	109	3	M8245
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ALKBH4 PLXNA3 FRAS1 ABCA2 SHISA5 MUS81 PPP6R1 TRRAP MADD HIRA TYK2 KMT2C PNPLA6 MROH1 PTPRS ZNF335 USP40 ZNF839 DNMBP IL4R FOXK1 WNK2 HTT	1.85e-09	1105	161	23	35748872
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA3 OTP PLXNA4 PLXNA2 PLXNB1	8.37e-09	16	161	5	17356169
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	3.05e-08	8	161	4	15661641
Pubmed	The role of neuropilins in cell signalling.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	5.47e-08	9	161	4	19909241
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	2.13e-07	12	161	4	21270798
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	3.06e-07	13	161	4	10520995
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA3 PLXNA4 PLXNA2	3.88e-07	4	161	3	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA3 PLXNA4 PLXNA2	3.88e-07	4	161	3	25518740
Pubmed	A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.	PLXNA3 PLXNA2 PLXNB1	3.88e-07	4	161	3	8570614
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NSUN5P1 FAM53A WDR27 TRRAP TYK2 BPTF KMT2C CFAP20DC USF3 CMIP PNPLA6 GPR137C PTPRS USP40 CHD6 IFT122 ANKRD12 ZNF839 CLEC16A DAGLA WNK2 NSMAF HTT	4.17e-07	1489	161	23	28611215
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 PPP6R1 CSMD3 MADD MROH1 STARD9 NAV3 TCF25 CHD6 ANKRD12 CLEC16A PLXNA2	4.88e-07	407	161	12	12693553
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.00e-06	17	161	4	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.00e-06	17	161	4	17626059
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ABCA2 ZFYVE28 KMT2C SULF2 NRXN3 FBXL7 ABCA5 CNTNAP2 CARNS1 DNMBP DAGLA WNK2 PLXNB1	1.24e-06	529	161	13	14621295
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA3 PLXNA4 PLXNA2	3.36e-06	7	161	3	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA3 PLXNA4 PLXNA2	3.36e-06	7	161	3	19655386
Pubmed	A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	4.37e-06	24	161	4	28893946
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	NRXN3 PTPRD PTPRS	5.36e-06	8	161	3	37591863
Pubmed	Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.	PTPRD PTPRS PLXNA4	5.36e-06	8	161	3	28637841
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA3 PLXNA4 PLXNA2	5.36e-06	8	161	3	22368082
Pubmed	Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors.	PLXNA3 LHX6 PLXNA4	5.36e-06	8	161	3	18786357
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	8.31e-06	28	161	4	18617019
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA3 PLXNA4 PLXNA2	1.14e-05	10	161	3	18804103
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA3 PLXNA4 PLXNA2	2.08e-05	12	161	3	24179230
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA3 PLXNA4 PLXNA2	2.08e-05	12	161	3	23991118
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXNA3 PLXNA4 PLXNA2	2.08e-05	12	161	3	25839327
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA3 PLXNA4 PLXNA2	2.08e-05	12	161	3	31690636
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA3 PLXNA4 PLXNA2	2.08e-05	12	161	3	28407732
Pubmed	Two new cases of interstitial 7q35q36.1 deletion including CNTNAP2 and KMT2C.	KMT2C CNTNAP2	2.13e-05	2	161	2	34582124
Pubmed	Chromosomal region 16p13: further evidence of increased predisposition to immune diseases.	CIITA CLEC16A	2.13e-05	2	161	2	19221398
Pubmed	Isolation and characterization of mammalian HDAC10, a novel histone deacetylase.	HDAC6 HDAC10	2.13e-05	2	161	2	11677242
Pubmed	PTPRD and CNTNAP2 as markers of tumor aggressiveness in oligodendrogliomas.	PTPRD CNTNAP2	2.13e-05	2	161	2	35982066
Pubmed	Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1.	PTGES PTGER1	2.13e-05	2	161	2	17967902
Pubmed	Autoimmune disease association signals in CIITA and KIAA0350 are not involved in celiac disease susceptibility.	CIITA CLEC16A	2.13e-05	2	161	2	19317741
Pubmed	Histone deacetylase 10 structure and molecular function as a polyamine deacetylase.	HDAC6 HDAC10	2.13e-05	2	161	2	28516954
Pubmed	The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.	PTPRD PTPRS	2.13e-05	2	161	2	9566880
Pubmed	Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.	PLXNA3 PLXNA4	2.13e-05	2	161	2	24619647
Pubmed	A census of human transcription factors: function, expression and evolution.	TFEC TBX3 CUX2 ETS2 RFX8 LHX6 PRDM2 OTP USF3 PAX8 GLI3 ZNF335 HEY2 NR3C2 FOXK1	2.29e-05	908	161	15	19274049
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	PLXNA3 TBX3 CUX2 PTPRD PTPRS TCF25 PLXNA2 PLXNB1	2.39e-05	251	161	8	29031500
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA3 PLXNA4 PLXNA2	2.69e-05	13	161	3	11604131
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA3 PLXNA4 PLXNA2	2.69e-05	13	161	3	22723296
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA3 PLXNA4 PLXNA2	2.69e-05	13	161	3	25959730
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	PLXNA3 TBX3 CUX2 ETS2 ZNF318 ZBTB49 KMT2C OTP GLI3 NR3C2 RFPL3 PLXNA2 FOXK1	2.84e-05	709	161	13	22988430
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	PLXNA3 PLXNA4 PLXNA2	3.41e-05	14	161	3	20159958
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	ADGRG5 GPR39 GPR37L1 GPR137C GPR148	3.41e-05	79	161	5	12679517
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	CUX2 ESS2 SPATA31E1 KDM5D USF3 SLC12A2 PIP4P1 ATF7IP2 IRF2BPL WNK2	3.47e-05	430	161	10	35044719
Pubmed	HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme.	TBX3 ETS2 GLI3	4.25e-05	15	161	3	25453830
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	TFEC TBX3 CUX2 ETS2 LHX6 SP8 PAX8 GLI3 HEY2 NR3C2 FOXK1	5.01e-05	544	161	11	28473536
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXNA3 PLXNA4 PLXNA2	5.22e-05	16	161	3	18489001
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TBX3 HBS1L FRAS1 PPP6R1 MADD TYK2 PARP4 SULF2 TCF25 IFT122 CLEC16A PLXNB1	5.45e-05	650	161	12	38777146
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA2	6.37e-05	3	161	2	27397516
Pubmed	Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	6.37e-05	3	161	2	17296555
Pubmed	HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.	HDAC6 HTT	6.37e-05	3	161	2	16192271
Pubmed	LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.	PTPRD PTPRS	6.37e-05	3	161	2	31985401
Pubmed	Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.	PTPRD PTPRS	6.37e-05	3	161	2	20139422
Pubmed	Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.	PTPRD PTPRS	6.37e-05	3	161	2	33656439
Pubmed	Regulation of Tbx3 expression by anteroposterior signalling in vertebrate limb development.	TBX3 GLI3	6.37e-05	3	161	2	12376101
Pubmed	Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex.	PLXNA3 PLXNA4	6.37e-05	3	161	2	18523013
Pubmed	Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.	PLXNA4 PLXNA2	6.37e-05	3	161	2	22777942
Pubmed	IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling.	TYK2 IL4R	6.37e-05	3	161	2	8609418
Pubmed	Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.	HDAC6 HDAC10	6.37e-05	3	161	2	11861901
Pubmed	Polymorphisms in the inflammatory genes CIITA, CLEC16A and IFNG influence BMD, bone loss and fracture in elderly women.	CIITA CLEC16A	6.37e-05	3	161	2	23133532
Pubmed	Identification of plexin family molecules in mice.	PLXNA3 PLXNA2	6.37e-05	3	161	2	8806646
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA2	6.37e-05	3	161	2	18625214
Pubmed	Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.	PTPRD PTPRS	6.37e-05	3	161	2	9784606
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA3 PLXNA2	6.37e-05	3	161	2	11241833
Pubmed	Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.	PTPRD PTPRS	6.37e-05	3	161	2	25394468
Pubmed	Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses.	DUSP1 TICAM1	6.37e-05	3	161	2	16461893
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TBX3 HDAC6 TAF1C ZNF318 PPP6R1 TRRAP TYK2 BPTF SULF2 PNPLA6 SLC16A1 GLI3 RTL9 TCF25 KIF18B FOXK1	6.60e-05	1116	161	16	31753913
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	6.76e-05	47	161	4	35462405
Pubmed	Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.	CUX2 GPR37L1 LHX6 HEPACAM PTPRD GLRB CNTNAP2 PLXNA2 MOG	6.92e-05	376	161	9	24154525
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	FRAS1 ETS2 LIFR TK1 FOXK1 HTT	7.96e-05	152	161	6	34299191
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CUX2 KMT2C SULF2 FBXL7 CHD6 CLEC16A DAGLA	9.06e-05	225	161	7	12168954
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	HDAC6 KDM5D TRRAP BPTF CHD6 HDAC10	9.52e-05	157	161	6	30186101
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.01e-04	52	161	4	26633812
Pubmed	In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci.	TBX3 PLXNA4	1.27e-04	4	161	2	25552398
Pubmed	Hearing function and thresholds: a genome-wide association study in European isolated populations identifies new loci and pathways.	CMIP PTPRD	1.27e-04	4	161	2	21493956
Pubmed	Identification of the GlialCAM interactome: the G protein-coupled receptors GPRC5B and GPR37L1 modulate megalencephalic leukoencephalopathy proteins.	GPR37L1 HEPACAM	1.27e-04	4	161	2	34100078
Pubmed	Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins.	PLXNA3 PLXNA4	1.27e-04	4	161	2	15721238
Pubmed	Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family study.	ADGRG5 KMT2C	1.27e-04	4	161	2	20600896
Pubmed	The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.	PTPRD PTPRS	1.27e-04	4	161	2	8524829
Pubmed	Semaphorin-plexin signalling genes associated with human breast tumourigenesis.	PLXNA3 PLXNA2	1.27e-04	4	161	2	21925246
Pubmed	Structural basis of semaphorin-plexin signalling.	PLXNA2 PLXNB1	1.27e-04	4	161	2	20877282
Pubmed	Determination of cell adhesion sites of neuropilin-1.	PLXNA3 PLXNA2	1.27e-04	4	161	2	10725340
Pubmed	The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent neovascularization.	TICAM1 LIFR	1.27e-04	4	161	2	21998580
Pubmed	De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.	CIITA MOG	1.27e-04	4	161	2	11937578
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHGA7 PCDHGA4 LHX6 SP8	1.54e-04	58	161	4	30377227
Pubmed	TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development.	TBX3 ETS2 GLI3	1.61e-04	23	161	3	38828908
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	PLXNA3 PLXNA4 PLXNA2	1.83e-04	24	161	3	15869472
Pubmed	Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants.	LHX6 SP8 OTP	2.08e-04	25	161	3	23042297
Pubmed	Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.	PLXNA4 PLXNA2	2.11e-04	5	161	2	22593055
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	PLXNA3 PLXNA2	2.11e-04	5	161	2	25313870
Pubmed	Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.	PTPRD PTPRS	2.11e-04	5	161	2	10777529
Pubmed	Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases.	HDAC6 HDAC10	2.11e-04	5	161	2	14670976
Pubmed	Inhibition of viral pathogenesis and promotion of the septic shock response to bacterial infection by IRF-3 are regulated by the acetylation and phosphorylation of its coactivators.	HDAC6 TICAM1	2.11e-04	5	161	2	23532979
Pubmed	PGE₂ promotes apoptosis induced by cytokine deprivation through EP3 receptor and induces Bim in mouse mast cells.	PTGES PTGER1	2.11e-04	5	161	2	25054560
Pubmed	Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.	PTPRD PTPRS	2.11e-04	5	161	2	22357843
Pubmed	Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.	PTGES PTGER1	2.11e-04	5	161	2	8253813
Pubmed	Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS.	PLXNA3 PLXNA4	3.16e-04	6	161	2	20010807
Pubmed	Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.	PTPRD PTPRS	3.16e-04	6	161	2	19273906
Interaction	SEMA5B interactions	PLXNA3 TK1 PLXNA4 PLXNA2	4.53e-06	15	157	4	int:SEMA5B
Interaction	SEMA5A interactions	PLXNA3 PLXNA4 PLXNA2	1.59e-05	7	157	3	int:SEMA5A
GeneFamily	Plexins	PLXNA3 PLXNA4 PLXNA2 PLXNB1	1.60e-07	9	110	4	683
GeneFamily	Protein phosphatase 1 regulatory subunits\|Histone deacetylases, class IIB	HDAC6 HDAC10	3.67e-05	2	110	2	993
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDFY4 NSMAF	1.28e-03	9	110	2	1230
GeneFamily	Patatin like phospholipase domain containing	PNPLA6 PNPLA8	1.60e-03	10	110	2	466
GeneFamily	Maestro heat like repeat containing	MROH1 MROH7	1.95e-03	11	110	2	636
GeneFamily	Fibronectin type III domain containing	LIFR PTPRD PTPRS ATF7IP2 FNDC8	2.96e-03	160	110	5	555
GeneFamily	ATP binding cassette subfamily A	ABCA2 ABCA5	3.18e-03	14	110	2	805
ToppCell	moderate-Myeloid-pDC\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ADGRG5 CUX2 WDFY4 INSYN2A SULF2 CIITA PTPRS PLXNA4 SCT	2.03e-08	180	161	9	a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCell	NS-moderate-d_16-33-Myeloid-pDC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ADGRG5 CUX2 WDFY4 INSYN2A SULF2 CIITA PTPRS PLXNA4 SCT	2.03e-08	180	161	9	144818e69613296cde43f29cb8c20899c670b319
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF318 WDFY4 USF3 FCRL1 CIITA PIP4P1 CNTNAP2 IL4R	2.69e-08	131	161	8	a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCell	NS-critical-d_07-13-Myeloid-pDC\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ADGRG5 CUX2 WDFY4 INSYN2A CIITA PTPRS PLXNA4 SCT	1.61e-07	165	161	8	17d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF318 WDFY4 USF3 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	1.61e-07	165	161	8	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZNF318 PRDM2 USF3 FCRL1 CIITA CNTNAP2 HEATR5B IL4R	1.93e-07	169	161	8	c3a6179a64589a370108fea809b157839347759c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRG5 CUX2 WDFY4 SULF2 CIITA PTPRS PLXNA4 SCT	2.02e-07	170	161	8	b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF318 WDFY4 USF3 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	2.64e-07	176	161	8	ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|myeloid / Lineage, cell class and subclass	HYAL4 ADGRG5 CUX2 INSYN2A PTPRS GLRB PLXNA4 SCT	2.87e-07	178	161	8	f75591988bbbeba073b66329a3437cb9b02f7648
ToppCell	normal_Lung-B_lymphocytes\|normal_Lung / Location, Cell class and cell subclass	CUX2 WDFY4 FCRL1 SULF2 PTPRS CNTNAP2 PLXNA4 SCT	3.00e-07	179	161	8	5b89193486100b6754c1c5eca3105ea955805eae
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	CUX2 WDFY4 SULF2 CIITA PTPRS PLXNA4 SCT MSLN	5.53e-07	194	161	8	768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCell	Biopsy_Control_(H.)-Immune-pDCs\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ADGRG5 CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	5.74e-07	195	161	8	47d139215f0b51f5ea9b5fb09b1100e320e3f1e2
ToppCell	distal-3-Hematologic-Plasmacytoid_Dendritic\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADGRG5 CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	5.97e-07	196	161	8	6028b790abba9bad1d5373bab13eb24855988f48
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADGRG5 CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	6.20e-07	197	161	8	3a5908deb5c5a2bf06019a102fb1652233cf2a2a
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADGRG5 CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	6.45e-07	198	161	8	bb03744d8372405c278a0781e2f513bed00cf2b3
ToppCell	distal-2-Hematologic-Plasmacytoid_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADGRG5 CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	6.70e-07	199	161	8	78796b05d28b35e7361b6271d4a3858faa39c45c
ToppCell	severe-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF318 WDFY4 PRDM2 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	6.95e-07	200	161	8	0e86f52b6e146d9bbc728d8fb176fc2b53696558
ToppCell	mild-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF318 WDFY4 PRDM2 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	6.95e-07	200	161	8	222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADGRG5 CUX2 WDFY4 SULF2 CIITA PLXNA4 SCT	1.26e-06	150	161	7	57f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZNF318 WDFY4 USF3 FCRL1 CIITA PIP4P1 IL4R	1.86e-06	159	161	7	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGRG5 CUX2 WDFY4 SULF2 CIITA PLXNA4 SCT	2.11e-06	162	161	7	86a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCell	droplet-Lung-nan-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG5 EXTL1 ITGAE WDFY4 CIITA TK1 KIF18B	2.69e-06	168	161	7	96f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCell	metastatic_Brain-B_lymphocytes-GrB-secreting_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	CUX2 FAM117A SULF2 APLN PTPRS PLXNA4 SCT	2.79e-06	169	161	7	71f6761b9927f352e0ccc221ca373319915f4184
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	2.91e-06	170	161	7	92e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	2.91e-06	170	161	7	9f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ETS2 SULF2 CIITA MAP3K13 DNMBP PID1 MSLN	2.91e-06	170	161	7	cc66ac6846c58be9493eb270644ee3ce0f86cfea
ToppCell	CTRL-Lymphoid-pDC\|Lymphoid / Disease state, Lineage and Cell class	CUX2 ETS2 INSYN2A SULF2 PTPRS PLXNA4 SCT	3.39e-06	174	161	7	ff4315e9fad198cc323fc987deb8652da137cf98
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CUX2 WDFY4 INSYN2A CIITA PTPRS PLXNA4 SCT	3.79e-06	177	161	7	8887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CUX2 WDFY4 INSYN2A CIITA PTPRS PLXNA4 SCT	3.79e-06	177	161	7	507f06d31ab773099c9431b6f433899dc97b5566
ToppCell	NS-moderate-d_16-33-Lymphoid-B_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ADGRG5 WDFY4 PRDM2 FCRL1 CIITA CLEC17A DNAH8	3.79e-06	177	161	7	320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCell	facs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 HEPACAM PTPRD NAV3 PID1 MOG PLXNB1	4.24e-06	180	161	7	c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCell	facs-Marrow-B-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 HEPACAM PTPRD NAV3 PID1 MOG PLXNB1	4.24e-06	180	161	7	07ac979b21be2425294d9818c48b5a1e6f014c19
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 CUX2 GPR39 PCDHGA4 PTGES INSYN2A PGBD5	4.39e-06	181	161	7	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|normal_Lung / Location, Cell class and cell subclass	CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	4.72e-06	183	161	7	c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	TGFBR3 FBXL7 PTPRS GLI3 NAV3 MEDAG PID1	5.07e-06	185	161	7	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	5.26e-06	186	161	7	0096a61b1841784c913752b4f3639200446cc02c
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ETS2 CSMD3 KMT2C CMIP TCF25 HDAC10 DNAH8	5.26e-06	186	161	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	5.26e-06	186	161	7	6345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCell	moderate-Lymphoid-B_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ADGRG5 WDFY4 PRDM2 FCRL1 CIITA CLEC17A DNAH8	5.26e-06	186	161	7	fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	5.26e-06	186	161	7	9e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF318 WDFY4 PRDM2 FCRL1 CIITA CLEC17A IL4R	5.64e-06	188	161	7	d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	5.64e-06	188	161	7	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRG5 CUX2 WDFY4 INSYN2A PTPRS PLXNA4 SCT	5.64e-06	188	161	7	1f820cb19eb0e15f0eb69d07e457072bbdad8ecb
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	5.84e-06	189	161	7	784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	5.84e-06	189	161	7	37ecbd73408d462b47d7e5611f203143e08a2689
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRG5 CUX2 WDFY4 INSYN2A PTPRS PLXNA4 SCT	6.04e-06	190	161	7	c44aae2e0d3cc84a187e12917fd8c2d7483f41d8
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	TGFBR3 FBXL7 PTPRS GLI3 PLXNA4 NAV3 MEDAG	6.04e-06	190	161	7	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	6.04e-06	190	161	7	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	6.04e-06	190	161	7	07f21386ea6eb23416a537d2250e3042efe93fb0
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	CUX2 WDFY4 SULF2 CIITA PTPRS PLXNA4 SCT	6.04e-06	190	161	7	6892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCell	COVID-19_Severe-pDC\|COVID-19_Severe / disease group, cell group and cell class	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.04e-06	190	161	7	c5ab6b7492fb86aff3d2af3eb671c9f985ae4aeb
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRG5 CUX2 WDFY4 INSYN2A PTPRS PLXNA4 SCT	6.04e-06	190	161	7	705489ebbaf3d8e643498c3e507742114475fc55
ToppCell	BAL-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.25e-06	191	161	7	989bf108c7f2c78dd7f14481570f1819673a5469
ToppCell	BAL-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.25e-06	191	161	7	3e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCell	BAL-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.25e-06	191	161	7	bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	6.25e-06	191	161	7	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	6.25e-06	191	161	7	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	BAL-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.47e-06	192	161	7	d9ff2293358c8b031ba212021012e058014ff472
ToppCell	Severe_COVID-19-Myeloid-pDC\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.47e-06	192	161	7	f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCell	BAL-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.47e-06	192	161	7	2e8611d65090e39f1a6e74c972288e7b68376d15
ToppCell	BAL-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	6.47e-06	192	161	7	43569726df281eebe57499e0993b9fd9d36118c2
ToppCell	COVID_non-vent-Lymphocytic-B_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ZNF318 WDFY4 PRDM2 FCRL1 CIITA CNTNAP2 IL4R	6.69e-06	193	161	7	32d139f922cd19adc1cc1e0e9a828115be9945d6
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	TBX3 FRAS1 CUX2 NRXN3 ATF7IP2 CHD6 WNK2	6.69e-06	193	161	7	503a979328c68b096680b71359a26f02fafdff35
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TGFBR3 FBXL7 PTPRS GLI3 NAV3 MEDAG PID1	6.69e-06	193	161	7	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	COVID_non-vent-Lymphocytic-B_cell-\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ZNF318 WDFY4 PRDM2 FCRL1 CIITA CNTNAP2 IL4R	6.69e-06	193	161	7	91955c3773c9729a96e82f240f06b072367970d9
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-Naive_B_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	ZNF318 WDFY4 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	6.92e-06	194	161	7	20967afbadb3cf80ba9f4d7ebda4e64389252e70
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZNF318 WDFY4 PRDM2 BPTF FCRL1 CIITA CLEC17A	6.92e-06	194	161	7	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	10x5'-Liver-Myeloid_Dendritic\|Liver / Manually curated celltypes from each tissue	WDFY4 SULF2 CIITA PTPRS SCT PID1 MSLN	6.92e-06	194	161	7	e6391bc7073831847c469ef0b0c437118e1f151f
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TGFBR3 FBXL7 PTPRS GLI3 NAV3 MEDAG PID1	7.16e-06	195	161	7	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CUX2 WDFY4 INSYN2A SULF2 PTPRS PLXNA4 SCT	7.16e-06	195	161	7	fbc324c3435f32b9ca269d83333faecfe940d7fe
ToppCell	COVID-19-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	TFEC CUX2 WDFY4 SULF2 CIITA PTPRS SCT	7.16e-06	195	161	7	4a7c080230ce6a79335ecbeadecb0177b2c13625
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CUX2 WDFY4 INSYN2A PTPRS PLXNA4 SCT IRF2BPL	7.40e-06	196	161	7	170629b9ae82e9a911b93e8739dcd38176fbecb4
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDFY4 PRDM2 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	7.65e-06	197	161	7	f7a8440d2b8b17d9726c6fe3dd383effbfebab13
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ETS2 LHX6 SULF2 FBXL7 CIITA STARD9 NAV3	7.65e-06	197	161	7	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FRAS1 CSMD3 LIFR PTPRD GLI3 CNTNAP2 PID1	7.65e-06	197	161	7	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	COVID-19_Mild-Lymphoid_B\|COVID-19_Mild / Disease group, lineage and cell class	WDFY4 PRDM2 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	7.65e-06	197	161	7	ff25c0e184bd0f068014bc3f5eba3aee17511b87
ToppCell	Bronchial-10x5prime-Stromal-Mesofibroblastic-Mesothelia\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 CNTNAP2 PLXNA4 MEDAG CARNS1 RFPL3 MSLN	7.65e-06	197	161	7	26888af95a7cc082a1f1218af35b1f07cb9436ed
ToppCell	Bronchial-10x5prime-Stromal-Mesofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 CNTNAP2 PLXNA4 MEDAG CARNS1 RFPL3 MSLN	7.65e-06	197	161	7	438de7f0d35d81d5f5e41dcef7b2c54b6da03df4
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	WDFY4 PRDM2 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	7.65e-06	197	161	7	7cae4f3eabfebce101de7bb7defb17d6c5360b58
ToppCell	Biopsy_IPF-Immune-pDCs\|Biopsy_IPF / Sample group, Lineage and Cell type	ADGRG5 CUX2 WDFY4 SULF2 PTPRS PLXNA4 SCT	7.91e-06	198	161	7	aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCell	Biopsy_Other_PF-Mesenchymal-Mesothelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	FRAS1 SLC16A1 PLXNA4 MEDAG CARNS1 PSAPL1 MSLN	7.91e-06	198	161	7	86736f01e61bf4961f060b24ee1f1f48340737dd
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 HEPACAM PTPRD APLN SLC12A2 GLRB MOG	7.91e-06	198	161	7	731a90f7e68b19e387499d63e3979af78b503b0c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 HEPACAM PTPRD APLN SLC12A2 GLRB MOG	7.91e-06	198	161	7	43a2ce64fa309bac89a44ea320e87ae2cc39f782
ToppCell	distal-1-mesenchymal-Mesothelial\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRAS1 HEPACAM SLC16A1 GLI3 CNTNAP2 MEDAG MSLN	8.17e-06	199	161	7	8dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCell	mild-B_memory\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UROC1 WDFY4 PRDM2 FCRL1 CIITA CNTNAP2 DNAH8	8.17e-06	199	161	7	e6ac9a0959b0de2c6a99298feb7715aa80ade1dd
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADGRG5 CUX2 INSYN2A SULF2 PTPRS PLXNA4 SCT	8.45e-06	200	161	7	ef42753c9fbe3770e3f415cd7ab412654d359edb
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_naive\|COVID-19_Mild / Disease, condition lineage and cell class	WDFY4 PRDM2 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	8.45e-06	200	161	7	e6a43eff47195e1d39530ad49ad908fc06a8b038
ToppCell	Macroglial\|World / cells hierarchy compared to all cells using T-Statistic	GPR37L1 HEPACAM FBXL7 GLI3 CARNS1 MOG PLXNB1	8.45e-06	200	161	7	e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-B-B_naive\|COVID-19_Severe / Disease, condition lineage and cell class	ZNF318 WDFY4 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	8.45e-06	200	161	7	5ba9c541fa356d34f392a63274dcd7bfb844cbb6
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 HEPACAM SULF2 PTPRD SLC12A2 GLRB MOG	8.45e-06	200	161	7	56f1f007ba8c9188a4b10e52744f1e50dc0f155a
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SHISA5 ETS2 LHX6 TGFBR3 LIFR CMIP MAP3K13	8.45e-06	200	161	7	50b8788494b744e0f0ec8c4d67a1c90ae09dca65
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SHISA5 ETS2 LHX6 TGFBR3 LIFR CMIP MAP3K13	8.45e-06	200	161	7	f5f24273bee3259a4a3be99ba53b88defa1286c0
ToppCell	severe-B_naive\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF318 WDFY4 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	8.45e-06	200	161	7	306df1f498ac2188eaf9f2a8d002bb73bdb9642d
ToppCell	mild-B_naive\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	WDFY4 PRDM2 FCRL1 CIITA CLEC17A CNTNAP2 IL4R	8.45e-06	200	161	7	d0467cab6a42bf780aa49046bf3231ca161dc144
ToppCell	droplet-Heart-nan-3m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG5 ITGAE WDFY4 FCRL1 CIITA DNMBP	1.21e-05	140	161	6	ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCell	control-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PLXNA3 CLEC17A ZNF335 ATF7IP2 CARNS1 MSLN	1.53e-05	146	161	6	69e9c1ec6eec1151290227902e75e77a4aecc8db
ToppCell	Mild/Remission-B_naive-4\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PRDM2 USF3 FCRL1 CIITA CNTNAP2 IL4R	1.66e-05	148	161	6	dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCell	LPS_only-Myeloid-Dendritic_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRG5 TFEC CUX2 WDFY4 SULF2 SCT	1.66e-05	148	161	6	cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADGRG5 KDM5D CIITA HDAC10 DNAH8 RUSF1	1.79e-05	150	161	6	53de595376a9fc92491dfd58ff25938b0bf79903
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADGRG5 KDM5D CIITA HDAC10 DNAH8 RUSF1	1.79e-05	150	161	6	e4b40b3243ed26d0c46bf196ac06e148834e7ed2
Disease	Addison Disease	CIITA CLEC16A	8.09e-05	3	154	2	C0001403
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	WDFY4 NSMAF	1.61e-04	4	154	2	DOID:2935 (implicated_via_orthology)
Disease	hippocampal volume	MADD SP8 PTPRD GLI3 NR3C2 ELAC1 PLXNA2 WNK2	1.76e-04	297	154	8	EFO_0005035
Disease	Sarcosine measurement	PCDHGA7 PCDHGA4 PCDHGA8	2.29e-04	23	154	3	EFO_0021668
Disease	Hydronephrosis	PTGES PTGER1	2.68e-04	5	154	2	C0020295
Disease	Addison's disease (is_implicated_in)	CIITA CLEC16A	2.68e-04	5	154	2	DOID:13774 (is_implicated_in)
Disease	mental development measurement	PCDHGA7 PCDHGA4 PCDHGA8	2.95e-04	25	154	3	EFO_0008230
Disease	Colorectal Carcinoma	TFEC CSMD3 LIFR KMT2C PTPRD ABCA5 PAX8 PTPRS TK1 GLI3 NR3C2 DNAH8	3.32e-04	702	154	12	C0009402
Disease	Autistic Disorder	TAF1C CSMD3 TRRAP WDFY4 NRXN3 CNTNAP2 SCT	4.60e-04	261	154	7	C0004352
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGA7 PCDHGA4 PTPRD PCDHGA8	5.28e-04	71	154	4	EFO_0007878, EFO_0007979
Disease	multiple sclerosis (is_implicated_in)	CIITA CLEC16A IL4R MOG	5.87e-04	73	154	4	DOID:2377 (is_implicated_in)
Disease	waist-hip ratio	CUX2 FAM53A DUSP1 ZNF318 SP8 BPTF CMIP NRXN3 PTPRD CIITA PTPRS GLI3 NAV3 IFT122 CLEC16A HTT	7.05e-04	1226	154	16	EFO_0004343
Disease	nasal disorder	NRXN3 CLEC16A IL4R	8.07e-04	35	154	3	MONDO_0002436
Disease	Bladder Neoplasm	OR8S1 PRDM2 BPTF KMT2C CHD6	8.59e-04	140	154	5	C0005695
Disease	Malignant neoplasm of urinary bladder	OR8S1 PRDM2 BPTF KMT2C CHD6	8.87e-04	141	154	5	C0005684
Disease	choroid plexus volume measurement	CNTNAP2 PLXNA4	9.51e-04	9	154	2	EFO_0010293
Disease	cognitive decline measurement	HIRA TGFBR3 NRXN3 PTPRD USP40 ATF7IP2 CNTNAP2 CHD6 PGBD5	1.07e-03	486	154	9	EFO_0007710
Disease	IGF-1 measurement	TBX3 CUX2 CMIP PAX8 STARD9 CFAP61 CARNS1 IL4R NSMAF	1.10e-03	488	154	9	EFO_0004627
Disease	serum albumin measurement	HBS1L MADD HSPB9 FAM117A SLC12A2 CIITA ABCA5 RTL9 IRF2BPL DAGLA	1.14e-03	592	154	10	EFO_0004535
Disease	nasopharyngeal neoplasm	FBXL7 CIITA CNTNAP2 PID1 MOG	1.20e-03	151	154	5	EFO_0004252
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5D NRXN3 CNTNAP2 NR3C2 CHD6	1.24e-03	152	154	5	DOID:0060041 (implicated_via_orthology)
Disease	brain connectivity measurement	PAX8 GLI3 NAV3 TCF25 HEY2 PLXNA2 MOG WNK2	1.25e-03	400	154	8	EFO_0005210
Disease	oral microbiome measurement	FRAS1 KMT2C CNTNAP2	1.38e-03	42	154	3	EFO_0801229
Disease	transient cerebral ischemia (biomarker_via_orthology)	DUSP1 MADD SLC12A2 WNK2 HTT	1.43e-03	157	154	5	DOID:224 (biomarker_via_orthology)
Disease	Paranoia	TYK2 DNAH8	1.44e-03	11	154	2	C1456784
Disease	endometrial adenocarcinoma (is_marker_for)	PTGES TGFBR3	1.44e-03	11	154	2	DOID:2870 (is_marker_for)
Disease	platelet aggregation	GP6 ESS2 PTPRD	1.68e-03	45	154	3	GO_0070527
Disease	hematologic cancer (implicated_via_orthology)	CUX2 TYK2	2.03e-03	13	154	2	DOID:2531 (implicated_via_orthology)
Disease	gamma-glutamylleucine measurement	CUX2 CARNS1	2.03e-03	13	154	2	EFO_0021140
Disease	HOMA-B	CUX2 TGFBR3 NAV3	3.00e-03	55	154	3	EFO_0004469
Disease	DiGeorge Syndrome	ESS2 HIRA	3.10e-03	16	154	2	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	ESS2 HIRA	3.10e-03	16	154	2	C0795907
Disease	pro-hydroxy-pro measurement	APLN NR3C2	3.10e-03	16	154	2	EFO_0021132
Disease	lysosomal storage disease (implicated_via_orthology)	TFEC PSAPL1	3.10e-03	16	154	2	DOID:3211 (implicated_via_orthology)
Disease	response to darapladib, Diarrhea	SP8 APLN	3.10e-03	16	154	2	EFO_0008395, HP_0002014
Disease	Shprintzen syndrome	ESS2 HIRA	3.10e-03	16	154	2	C0220704
Disease	Polydactyly	TBX3 FRAS1 PNPLA6 GLI3	3.35e-03	117	154	4	C0152427
Disease	rheumatoid arthritis (is_implicated_in)	CIITA CLEC16A IL4R	3.49e-03	58	154	3	DOID:7148 (is_implicated_in)
Disease	androstenedione measurement, estrone measurement	PTPRD PGBD5	3.92e-03	18	154	2	EFO_0007970, EFO_0007972
Disease	neuroimaging measurement, brain volume measurement	BPTF FBXL7 NAV3 HEY2 KIF18B WNK2	4.00e-03	286	154	6	EFO_0004346, EFO_0006930
Disease	pursuit maintenance gain measurement	LIFR CMIP PTPRD PLXNA2	4.01e-03	123	154	4	EFO_0008433
Disease	Malignant neoplasm of breast	TBX3 TICAM1 ETS2 ZNF318 GALNT16 SLC2A10 SULF2 PTPRD MROH7 HEY2 MAP3K13 RUSF1 PLXNB1	4.25e-03	1074	154	13	C0006142
Disease	diet measurement, body mass index	INSYN2A CNTNAP2	4.83e-03	20	154	2	EFO_0004340, EFO_0008111

Protein segments in the cluster

Peptide	Gene	Start	Entry
STLMNILCGLCPPSD	ABCA5	521	Q8WWZ7
LSPTVLSMCREAPGS	ALKBH4	186	Q9NXW9
MAAAATGSPLLLTPS	ERFL	136	A0A1W2PQ73
LMGLAETPGCATLLP	DCAF4	246	Q8WV16
LNCMLTSLPNGSSVI	CFAP54	741	Q96N23
LDSDIPCTPLNTLFM	CFAP61	91	Q8NHU2
TLGALMPSLPSCLSN	COG7	286	P83436
MPSLPSCLSNGVERA	COG7	291	P83436
CLSNFTAPMGTVLSP	CSMD3	721	Q7Z407
PQGSSQCATMELGPL	CIITA	16	P33076
DQIPMPFSSSSLSCL	CIITA	206	P33076
LLEPGNLASSPSMSL	FAM117A	261	Q9C073
SLMSSEELCPTAGLP	FBXO4	196	Q9UKT5
PACSTMSIELGPQAD	CMIP	436	Q8IY22
QELGLPCSSPAAMRL	CARNS1	486	A5YM72
SLTAVCGGSLMPLPD	APLN	16	Q9ULZ1
MGRSLDQTSPCPLVL	DNMBP	681	Q6XZF7
CLSPGSSEMSLQPDL	ANKRD12	566	Q6UB98
TCSLPQGMAKPEDSL	CUX2	381	O14529
SPVGCLSETPDSSNM	BPTF	656	Q12830
CLAATSTLMSSPGSP	GALNT16	486	Q8N428
ISPPSCMTLILGSNE	MROH7	321	Q68CQ1
DSGDPPLSSNMSLSL	PCDHGA7	536	Q9Y5G6
NLPMDSCVATKSLSP	PAX8	141	Q06710
DCLSIFGSSPMPGTL	RAD1	91	O60671
SETALACSPPMQCLS	INSYN2A	301	Q6ZSG2
DSGDPPLSSNMSLSL	PCDHGA8	536	Q9Y5G5
TGDRLLAMPPNETCT	HBS1L	516	Q9Y450
MSSLLSPPIACQSPA	ZFYVE28	356	Q9HCC9
LLMTASDSGDPPLSS	PCDHGA4	561	Q9Y5G9
SALRMPSTGSVAPCV	HEY2	236	Q9UBP5
MAGSPVFLCTLAPLN	SLC16A1	151	P53985
SAPLLSRCVSMPGDI	PNPLA6	411	Q8IY17
MDSPSNATVPCGFLL	OR10AC1	1	Q8NH08
TSGLECSSCQPPLLM	FRAS1	476	Q86XX4
SLSSCNPPAMATSAE	GLI3	1026	P10071
MASPSLPGSDCSQII	GPR39	1	O43194
PSTPNMAAGQLCTEL	KMT2C	3666	Q8NEZ4
MTPRGFSCLLLPTSE	MTRNR2L6	1	P0CJ73
RSLLPDASITMCPSC	IFT122	1196	Q9HBG6
KEMCGSPAPLSSNSS	TRIM71	16	Q2Q1W2
SPLNMTSSVCSPAGI	NR3C2	196	P08235
LPTCMASAEQLLLAP	MADD	356	Q8WXG6
QSSDAFPLCLMLLSP	NAA80	96	Q93015
LVSFAVPMDSGPSCL	SLC2A10	316	O95528
LPSNLSPTAMTCCLT	HSPB9	106	Q9BQS6
SPTAMTCCLTPSGQL	HSPB9	111	Q9BQS6
PMTDTAPLLFTCSNL	GPR137C	401	Q8N3F9
SGSSAACPSLMPLLQ	KDM5D	1516	Q9BY66
SSGSQLCEDLLLMPT	ITGAE	756	P38570
MSPSPTALFCLGLCL	GP6	1	Q9HCN6
DASCPMLPTALVSLS	IRF2BPL	501	Q9H1B7
MFSLPLSLPLCEDTA	PID1	1	Q7Z2X4
MSEIVCVSPPSSNGL	PLXNA2	1001	O75051
LLCDSPSQTGRQPVM	PLXNA3	1181	P51805
ATEMTCQAPALALGP	PLXNA4	1091	Q9HCM2
QSPALLTGSGVMCPS	PLXNB1	576	O43157
LFSSCSPPGMVLDGS	MSTO1	481	Q9BUK6
MSPCGPLNLSLAGEA	PTGER1	1	P34995
MEKASASSCPAPLEG	NAV3	571	Q8IVL0
GPLQGSSCLEMLSTS	FAM205A	131	Q6ZU69
GLLDSMCPASTPSVL	ETS2	216	P15036
TRTPLICFLSMGSDP	DNAH8	3906	Q96JB1
LSMTSEAGLPCLSDQ	NRXN3	1381	Q9Y4C0
CPSTMKNPASLLFSL	LCT	286	P09848
TTRCLEGTAPPAMAQ	LHX6	11	Q9UPM6
LSCPLDLTLFPMDTQ	GLRB	181	P48167
MALPTARPLLGSCGT	MSLN	1	Q13421
VLLDPSCSGSGMPSR	NSUN5P1	36	Q3KNT7
RLPMASALPEALCSQ	PARP4	1476	Q9UKK3
PLSATCALFEVMSTP	MROH1	1196	Q8NDA8
MSCINLPTVLPGSPS	TK1	1	P04183
LGPSAMQNCSTPLAL	KIF18B	701	Q86Y91
MAGAACEPVARPSLT	MEDAG	1	Q5VYS4
MASLSRPSLPSCLCS	MOG	1	Q16653
TATMLCAASGNPDPE	PTPRS	151	Q13332
LPGSSPDLISTAMAA	MAP3K13	691	O43283
MSPQGPAVLSLGSLC	PRICKLE4	1	Q2TBC4
SDCTGLPLSMLTNPA	PGBD5	371	Q8N414
SMCSPVPLLAAASGQ	VENTXP1	6	P0C5K6
METPGASASSLLLPA	ESS2	1	Q96DF8
NLSLLAPCLSLGMSE	HTT	2141	P42858
GPMAPCQSALESIQS	HDAC10	331	Q969S8
DMGESCLLPPSGSTS	IL4R	426	P24394
ILSDLPSLCSPAGCM	HEATR5B	1761	Q9P2D3
AFCSLALSAPMGSDP	CCL4L1	16	Q8NHW4
GDPLPTESRLMNSCL	GFRA3	31	O60609
SCPELCSKQSTPMGL	DUSP1	131	P28562
CSKQSTPMGLSLPLS	DUSP1	136	P28562
GLLSPPMATTCTSTA	CHD6	2536	Q8TD26
LSMRTLSTPSPALIC	FBXL7	46	Q9UJT9
LASLSTLDLCGMTPV	FBXO15	236	Q8NCQ5
GSPVTLTCKMPFLQS	FCRL1	31	Q96LA6
GTLDSCIMKPSASLP	GPR37L1	281	O60883
MRLPGCTLAASEAAP	C14orf93	181	Q9H972
PCMPQAASNTSLGLG	GPR148	26	Q8TDV2
MVSGQCTLPGLSLLP	CENPJ	181	Q9HC77
SGVSPSPGSLMTLCL	HYAL4	456	Q2M3T9
MTTQVCCSPGLASPL	CARD19	131	Q96LW7
LMSPRSGGLQTPECL	FOXK1	426	P85037
LTSAGILPVMQSLCP	ABCA2	61	Q9BZC7
PLPMACTLSQFLASN	ATF7IP2	636	Q5U623
MDLTPTGLSSQECLA	DAGLA	1001	Q9Y4D2
SNMALSSCLLLPGDA	NSMAF	671	Q92636
ALPAMPTARCSCSSL	KLHDC8B	311	Q8IXV7
SCMVENPISQGRSLP	HEPACAM	216	Q14CZ8
ESNCGASPLTLSPMS	CNTNAP2	1211	Q9UHC6
SASLHTLLGDPCPML	HDAC6	396	Q9UBN7
RSSLPSQDAMLCSGP	HIRA	871	P54198
MATSLTSPCPLHLGA	DUOXA1	226	Q1HG43
MACGPGDLQSLTSPL	PRSS46P	1	E5RG02
LSAGLLCPSGSNMPI	SCT	71	P09683
LTSPDSGSAPMITCR	PIP4P1	71	Q86T03
TLDLSGCQLPAPMVT	NLRP6	816	P59044
GSSALKTLEMNPCTP	LIFR	891	P42702
SSPPSLGPDCLIMNS	PRDM2	446	Q13029
SDPMVPSCSLSLPLS	PRDM2	656	Q13029
LSQCSLAAGPPPNSM	OTP	236	Q5XKR4
RTATMLCAASGNPDP	PTPRD	141	P23468
GSALMIETARNPTCP	PNPLA8	546	Q9NP80
PCPSKSQMATRGLLD	FNDC8	141	Q8TC99
SLLMLPLVSGCPGFS	RUSF1	246	Q96GQ5
DSGALSPLLMPASDS	RTL9	96	Q8NET4
MLRGAPDSAPAQVCT	PSAPL1	121	Q6NUJ1
LTTALPSMAAAAGPL	TBX3	656	O15119
PLGLSDVPDLSFMCS	TAF1C	16	Q15572
MTSPLCRAASANALP	ODAD3	1	A5D8V7
CMASRGLSLFPESCP	SHISA5	31	Q8N114
MSPGDPCSSRALQVL	SPATA31E1	1006	Q6ZUB1
SAPDACLTMSPNSVG	STARD9	916	Q9P2P6
LVMSSPALPAFLLCS	PTGES	6	O14684
MPSLLPLSCSDISRS	OR8S1	181	Q8NH09
AMSQIPAGGTDCSLP	RO60	436	P10155
LLSLDAQTGECSSMP	EXTL1	136	Q92935
MLAATCNKIGSPSPS	SP8	1	Q8IXZ3
MSPVPGSACTALAAA	ADGRG5	306	Q8IZF4
EMSLLPTTCLSPTGR	CFAP20DC	471	Q6ZVT6
LTGMPPLSTPAAACT	CLEC16A	1021	Q2KHT3
PRNMTGLDLAAVTCP	CLEC17A	116	Q6ZS10
MAAPEQPLAISRGCT	RNPC3	1	Q96LT9
MSSLQALCSGLPLRP	UROC1	1	Q96N76
TLPPFMCNTGATDLQ	SSX9P	66	Q7RTT3
MACTGPSLPSAFDIL	TICAM1	1	Q8IUC6
LSQACASPSMEPLGV	RFX8	481	Q6ZV50
GCLLPQSQARPSSDM	STYXL2	781	Q5VZP5
CLVMTGAPNSRPALL	SLC12A2	791	P55011
ESPGPSCTLMALQSI	WDFY4	476	Q6ZS81
SDVSMPILGPSLLFC	MYCBPAP	396	Q8TBZ2
LPDGSAMSPLLTIAN	USF3	2201	Q68DE3
LSICPLMNSGTTDAP	RFPL3	296	O75679
LPGLLCTISLQSGSM	ELAC1	71	Q9H777
CVSTMLSLGPPPDSS	PPP6R1	406	Q9UPN7
QGSMLTPLSASDPLA	ZNF839	86	A8K0R7
LTSLGLSMPADPCEG	ZNF839	251	A8K0R7
IFMNGACSPSLLPTL	USP30	401	Q70CQ3
PINMGLTSASCPSSL	TFEC	106	O14948
PGMPCNSTLSLQSTL	ZBTB49	126	Q6ZSB9
MGQSLSVPASSCVLP	WDR27	401	A2RRH5
MLGSLADAAPSPAQC	WNK2	636	Q9Y3S1
ALPDPNMLVSDCTAS	ZNF335	111	Q9H4Z2
MLPPESPGLNNSISC	USP40	431	Q9NVE5
STPIGTSCQGAMLPS	TRRAP	2506	Q9Y4A5
SPARSAMCLTGSPQE	ZNF318	1896	Q5VUA4
TMFPGVLLPLLESCS	TCF25	456	Q9BQ70
MGPPSLVLCLLSATV	SULF2	1	Q8IWU5
ALMSSCLATAGPEPG	TGFBR3	11	Q03167
PECLPGGANSLSTAM	TYK2	781	P29597
LSSPCDSRGLPGITM	FAM53A	321	Q6NSI3
SGAMTSPNPLCSLLT	MUS81	441	Q96NY9