Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ZnF_C2HC	FAM90A14 RTL3 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	5.81e-09	55	86	7	SM00343
Domain	Znf_CCHC	FAM90A14 RTL3 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	5.81e-09	55	86	7	IPR001878
Domain	UDPGT	UGT2B15 UGT2B17	4.16e-03	21	86	2	PF00201
Domain	UDPGT	UGT2B15 UGT2B17	4.16e-03	21	86	2	PS00375
Domain	UDP_glucos_trans	UGT2B15 UGT2B17	4.16e-03	21	86	2	IPR002213
Domain	TUDOR	TDRD5 PHF20L1	4.98e-03	23	86	2	PS50304
Domain	TUDOR	TDRD5 PHF20L1	6.83e-03	27	86	2	SM00333
Domain	Tudor	TDRD5 PHF20L1	8.38e-03	30	86	2	IPR002999
Pathway	REACTOME_GLUCURONIDATION	UGT2A2 UGT2B15 UGT2B17	1.32e-04	24	59	3	MM14599
Pathway	REACTOME_GLUCURONIDATION	UGT2A2 UGT2B15 UGT2B17	1.50e-04	25	59	3	M17787
Pathway	WP_GLUCURONIDATION	UGT2A2 UGT2B15 UGT2B17	1.50e-04	25	59	3	MM15820
Pathway	WP_GLUCURONIDATION	UGT2A2 UGT2B15 UGT2B17	1.69e-04	26	59	3	M39404
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.69e-22	25	96	11	17684299
Pubmed	Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.76e-20	23	96	10	18602769
Pubmed	Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 PRLR FAM90A10	3.28e-11	164	96	10	22967998
Pubmed	Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.	UGT2B15 UGT2B17	7.54e-06	2	96	2	32660355
Pubmed	The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.	UGT2B15 UGT2B17	7.54e-06	2	96	2	1909870
Pubmed	Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.	UGT2B15 UGT2B17	7.54e-06	2	96	2	24121496
Pubmed	Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.	UGT2B15 UGT2B17	7.54e-06	2	96	2	3117546
Pubmed	Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.	UGT2B15 UGT2B17	7.54e-06	2	96	2	24267955
Pubmed	Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.	UGT2B15 UGT2B17	7.54e-06	2	96	2	22170718
Pubmed	Ectomesenchymal Chondromyxoid Tumor: A Neoplasm Characterized by Recurrent RREB1-MKL2 Fusions.	MRTFB RREB1	7.54e-06	2	96	2	29912715
Pubmed	Ankyrin-G Inhibits Endocytosis of Cadherin Dimers.	ANK3 CDH5	7.54e-06	2	96	2	26574545
Pubmed	Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.	UGT2B15 UGT2B17	7.54e-06	2	96	2	3105095
Pubmed	UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.	UGT2B15 UGT2B17	7.54e-06	2	96	2	17848572
Pubmed	Studies on the mechanism of local and extra-intestinal tissue manifestations in AOM-DSS-induced carcinogenesis in BALB/c mice: role of PARP-1, NLRP3, and autophagy.	PARP1 NLRP3	7.54e-06	2	96	2	38091080
Pubmed	Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.	UGT2B15 UGT2B17	7.54e-06	2	96	2	27496708
Pubmed	Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.	UGT2B15 UGT2B17	7.54e-06	2	96	2	28228532
Pubmed	Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.	UGT2B15 UGT2B17	7.54e-06	2	96	2	15666817
Pubmed	The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.	UGT2B15 UGT2B17	7.54e-06	2	96	2	17698910
Pubmed	Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.	UGT2B15 UGT2B17	2.26e-05	3	96	2	19572376
Pubmed	PARP1 orchestrates variant histone exchange in signal-mediated transcriptional activation.	PARP1 EP400	2.26e-05	3	96	2	24145797
Pubmed	Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.	UGT2B15 UGT2B17	2.26e-05	3	96	2	26163549
Pubmed	Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.	UGT2B15 UGT2B17	2.26e-05	3	96	2	20736324
Pubmed	Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation.	PARP1 NLRP3	2.26e-05	3	96	2	27010854
Pubmed	Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.	UGT2B15 UGT2B17	2.26e-05	3	96	2	26385605
Pubmed	The involvement of Sting in exacerbating acute lung injury in sepsis via the PARP-1/NLRP3 signaling pathway.	PARP1 NLRP3	2.26e-05	3	96	2	38848887
Pubmed	Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.	UGT2B15 UGT2B17	2.26e-05	3	96	2	28882566
Pubmed	PGC-1α inhibits NLRP3 signaling through transcriptional activation of POP1 to alleviate inflammation and strengthen osteogenic differentiation of lipopolysaccharide-induced human periodontal stem cells.	POP1 NLRP3	2.26e-05	3	96	2	38763227
Pubmed	PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages.	PARP1 NLRP3	2.26e-05	3	96	2	35098371
Pubmed	Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.	UGT2B15 UGT2B17	2.26e-05	3	96	2	17988216
Pubmed	Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.	UGT2B15 UGT2B17	2.26e-05	3	96	2	23223495
Pubmed	Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.	UGT2B15 UGT2B17	2.26e-05	3	96	2	18302198
Pubmed	The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.	UGT2B15 UGT2B17	2.26e-05	3	96	2	30689982
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	PARP1 LIMA1 EP400 DACH2 PRPF3 AHNAK FNBP1L HDLBP	3.29e-05	444	96	8	34795231
Pubmed	CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.	JARID2 EP400 EPC1	3.47e-05	23	96	3	31281901
Pubmed	Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes.	PARP1 NLRP3	4.51e-05	4	96	2	20713892
Pubmed	TIMP-1 regulates cell proliferation by interacting with the ninth zinc finger domain of PLZF.	PARP1 ZBTB16	4.51e-05	4	96	2	17340613
Pubmed	Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.	UGT2B15 UGT2B17	4.51e-05	4	96	2	18281521
Pubmed	Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.	UGT2B15 UGT2B17	4.51e-05	4	96	2	26176234
Pubmed	Jarid2 is induced by TCR signalling and controls iNKT cell maturation.	JARID2 ZBTB16	4.51e-05	4	96	2	25105474
Pubmed	The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease.	POP1 NLRP3	4.51e-05	4	96	2	26275995
Pubmed	The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1.	PARP1 SLC25A4	7.50e-05	5	96	2	16429131
Pubmed	MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons.	ANK3 MAP2	7.50e-05	5	96	2	28426968
Pubmed	Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis.	SLC25A4 NLRP3	7.50e-05	5	96	2	29255148
Pubmed	Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain.	MAP2 DPYSL5	7.50e-05	5	96	2	15834957
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	MED24 PARP1 LIMA1 DIMT1 AHNAK GART HDLBP ARF6	7.89e-05	503	96	8	36217030
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	PARP1 LIMA1 EP400 PRPF3 AHNAK HDLBP	1.09e-04	271	96	6	32433965
Pubmed	Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer.	UGT2B15 UGT2B17	1.12e-04	6	96	2	21365123
Pubmed	Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells.	PARP1 NLRP3	1.12e-04	6	96	2	28687790
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	PARP1 EP400 PELP1 HSPA4L PRPF3 AHNAK POP1	1.14e-04	394	96	7	27248496
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	FSIP2 PARP1 LIMA1 GOPC HSPA4L AHNAK HDLBP	1.23e-04	399	96	7	35987950
Pubmed	Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.	UGT2B15 UGT2B17	1.57e-04	7	96	2	26074487
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	MED24 INTS6 LIMA1 PELP1 COG6 NUP88 IDH3A ECPAS	1.65e-04	560	96	8	35241646
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	VAPA LIMA1 MRTFB ANK3 AHNAK MARVELD2 FNBP1L HDLBP	1.75e-04	565	96	8	25468996
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	VAPA NUDT12 GOPC EP400 CDK12 TMEM94 DDHD1 KIAA1191 RREB1	1.98e-04	733	96	9	34672954
Pubmed	Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.	UGT2B15 UGT2B17	2.09e-04	8	96	2	32093886
Pubmed	Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.	UGT2B15 UGT2B17	2.09e-04	8	96	2	22579593
Pubmed	HIV-1 protease-induced apoptosis.	PARP1 SLC25A4	2.09e-04	8	96	2	24886575
Pubmed	The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.	UGT2B15 UGT2B17	2.09e-04	8	96	2	18719240
Pubmed	Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development.	MAP2 ARF6	2.09e-04	8	96	2	38227057
Pubmed	Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.	UGT2B15 UGT2B17	2.09e-04	8	96	2	20142249
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	EP400 PELP1 EPC1	2.16e-04	42	96	3	35705031
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	PARP1 EP400 PELP1 HSPA4L PRPF3 POP1 NUP88	2.24e-04	440	96	7	34244565
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	INTS6 MRTFB ZBTB16 ANK3 MAP2 PRPF3 ATXN7L1 DPYSL5 KIAA1328 FNIP1 IQCN FNBP1L ECPAS	2.28e-04	1489	96	13	28611215
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	VAPA PARP1 INTS6 EP400 PELP1 SLC25A4 PRPF3 AHNAK EPC1 POP1 NUP88 RREB1	2.34e-04	1294	96	12	30804502
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MED24 PARP1 EP400 SLC25A4 PRPF3 GART NUP88 ECPAS HDLBP	2.44e-04	754	96	9	35906200
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	VAPA MRTFB GOPC AHNAK GART ECPAS HDLBP	2.53e-04	449	96	7	31732153
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	PARP1 LIMA1 PRPF3 GART NUP88 ZNF75D SARDH	2.60e-04	451	96	7	36168627
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PARP1 LIMA1 MRTFB EP400 PRPF3 CDK12 AHNAK GART NUP88 HDLBP	2.61e-04	934	96	10	33916271
Pubmed	A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum.	MAP2 ADAMTS2	2.68e-04	9	96	2	31491533
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MED24 LIMA1 EP400 CDK12 POP1 IQCN RREB1 ECPAS HDLBP	2.96e-04	774	96	9	15302935
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PARP1 EP400 PELP1 SLC25A4 PRPF3 CDK12 AHNAK POU4F3 RREB1 HDLBP	3.09e-04	954	96	10	36373674
Pubmed	Hdac6 regulates Tip60-p400 function in stem cells.	LIMA1 EP400 EPC1	3.22e-04	48	96	3	24302573
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	PARP1 EP400 PELP1 AHNAK RREB1 HDLBP	3.26e-04	332	96	6	32786267
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	PARP1 LIMA1 DIMT1 ANK3 HSPA4L CDK12 AHNAK GART IDH3A ECPAS HDLBP	3.31e-04	1149	96	11	35446349
Pubmed	The human plasma proteome: history, character, and diagnostic prospects.	IDH3A HDLBP	3.34e-04	10	96	2	12488461
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	LIMA1 MRTFB AHNAK ECPAS HDLBP	3.41e-04	216	96	5	31519766
Pubmed	The highly conserved and multifunctional NuA4 HAT complex.	EP400 EPC1	4.08e-04	11	96	2	15196461
Pubmed	Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity.	PARP1 LIMA1 AHNAK	4.08e-04	52	96	3	23182705
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	PARP1 MAP2 HSPA4L CDK12 AHNAK ECPAS HDLBP	4.71e-04	498	96	7	36634849
Pubmed	Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.	UGT2B15 UGT2B17	4.89e-04	12	96	2	20308471
Pubmed	Heat-shock protein HSPA4 is required for progression of spermatogenesis.	ZBTB16 HSPA4L	4.89e-04	12	96	2	21487003
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	PARP1 LIMA1 PELP1 AHNAK POP1	4.91e-04	234	96	5	36243803
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	LIMA1 MRTFB EP400 PRPF3 CDK12 POP1 DPYSL5	5.18e-04	506	96	7	30890647
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	VAPA DIMT1 SLC25A4 GART DPYSL5 IDH3A HDLBP ARF6	5.19e-04	665	96	8	30457570
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	VAPA PARP1 DIMT1 PELP1 SLC25A4 HSPA4L PRPF3 AHNAK GART POP1 FNBP1L HDLBP	5.23e-04	1415	96	12	28515276
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	ANK3 NUP88	5.77e-04	13	96	2	31427429
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	PARP1 EP400 PELP1 AHNAK POP1	6.04e-04	245	96	5	21182205
Pubmed	Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development.	MRTFB MAP2	6.71e-04	14	96	2	20534669
Pubmed	Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.	PARP1 CDH5	6.71e-04	14	96	2	31519886
Pubmed	Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.	GOPC CCDC190	6.71e-04	14	96	2	23266556
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	PARP1 PRPF3 CDK12 AHNAK POP1	6.74e-04	251	96	5	31076518
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	VAPA DTD1 PARP1 LIMA1 DIMT1 PELP1 PRPF3 AHNAK GART POP1 HDLBP	7.00e-04	1257	96	11	36526897
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	VAPA PARP1 DIMT1 PELP1 AHNAK GART ECPAS ARF6	7.73e-04	707	96	8	19738201
Pubmed	Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.	MED24 ZBTB16	7.73e-04	15	96	2	19762545
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	VAPA PARP1 ANK3 HSPA4L AHNAK GART ECPAS HDLBP	7.80e-04	708	96	8	39231216
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	MED24 EP400 EPC1	7.86e-04	65	96	3	22496869
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	PARP1 PHF20L1 EP400 PELP1	8.12e-04	150	96	4	28242625
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	LIMA1 MRTFB ANK3 EP400 CDK12 AHNAK HDLBP	8.35e-04	549	96	7	38280479
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	VAPA LIMA1 SLC25A4 MAP2 HSPA4L DPYSL5 IDH3A	8.62e-04	552	96	7	36293380
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	VAPA LIMA1 ANK3 ATXN7L1 AHNAK POP1 MYOM2 RREB1 KLHDC9 PRLR HDLBP	8.81e-04	1293	96	11	15342556
Cytoband	8p23.1	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	2.91e-14	154	96	11	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 MYOM2 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	9.92e-14	234	96	12	chr8p23
Cytoband	4q13	UGT2B15 UGT2B17	4.46e-04	15	96	2	4q13
Cytoband	18p11.22	VAPA PIEZO2	5.77e-04	17	96	2	18p11.22
Cytoband	5p13.2	CPLANE1 PRLR	1.93e-03	31	96	2	5p13.2
GeneFamily	UDP glucuronosyltransferases	UGT2A2 UGT2B15 UGT2B17	9.33e-05	32	50	3	363
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MRTFB ANK3 CCDC190 FGF14 C11orf16 CPLANE1	2.04e-06	193	86	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MAP2 DNAH17 LTK ATG2A NLRP3	5.38e-06	130	86	5	6c6a8b77af08b30b424d4f5def37315d3c6e28b2
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_fibroblast-mesenchymal_B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MAP2 DNAH17 LTK ATG2A NLRP3	5.38e-06	130	86	5	0706092f6b466585b3b4808b3b982a122d66cfcf
Disease	cholic acid glucuronide measurement	UGT2B15 UGT2B17	2.12e-05	3	79	2	EFO_0800574
Disease	X-25937 measurement	UGT2B15 UGT2B17	4.23e-05	4	79	2	EFO_0800937
Disease	IGF-1 measurement	MED24 CCDC190 DPYSL5 UGT2B15 UGT2B17 RREB1 PRLR HDLBP	4.93e-05	488	79	8	EFO_0004627
Disease	X-24574 measurement	UGT2B15 UGT2B17	1.47e-04	7	79	2	EFO_0800897
Disease	deoxycholic acid glucuronide measurement	UGT2B15 UGT2B17	1.96e-04	8	79	2	EFO_0800575
Disease	4-androsten-3alpha,17alpha-diol monosulfate (3) measurement	UGT2B15 UGT2B17	3.14e-04	10	79	2	EFO_0022090
Disease	DNA repair protein RAD51 homolog 4 measurement	UGT2B15 UGT2B17	3.83e-04	11	79	2	EFO_0801531
Disease	5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement	UGT2B15 UGT2B17	4.59e-04	12	79	2	EFO_0800291
Disease	androstenediol (3alpha, 17alpha) monosulfate (3) measurement	UGT2B15 UGT2B17	5.42e-04	13	79	2	EFO_0800293
Disease	X-19141 measurement	UGT2B15 UGT2B17	5.42e-04	13	79	2	EFO_0800799
Disease	5alpha-androstan-3alpha,17alpha-diol monosulfate measurement	UGT2B15 UGT2B17	6.31e-04	14	79	2	EFO_0800283
Disease	3-hydroxyphenylacetic acid measurement	VAPA PIEZO2	6.31e-04	14	79	2	EFO_0010448
Disease	brain measurement, neuroimaging measurement	ANK3 MAP2 PRPF3 DPYSL5 KIAA1755 FGF14 RREB1	6.85e-04	550	79	7	EFO_0004346, EFO_0004464
Disease	5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement	UGT2B15 UGT2B17	1.05e-03	18	79	2	EFO_0800288
Disease	etiocholanolone glucuronide measurement	UGT2B15 UGT2B17	1.18e-03	19	79	2	EFO_0800362
Disease	androsterone glucuronide measurement	UGT2B15 UGT2B17	1.30e-03	20	79	2	EFO_0800317
Disease	alkaline phosphatase measurement	MED24 ADAMTS2 AHNAK UGT2B15 UGT2B17 FNBP1L RREB1 NLRP3 HDLBP	1.55e-03	1015	79	9	EFO_0004533
Disease	waist-hip ratio	ANK3 ADAMTS2 ATXN7L1 AHNAK MYO3B DNAH17 EPC1 KIAA1328 IQCN RREB1	1.58e-03	1226	79	10	EFO_0004343
Disease	X-24947 measurement	UGT2B15 UGT2B17	1.58e-03	22	79	2	EFO_0800910
Disease	epiandrosterone sulfate measurement	UGT2B15 UGT2B17	2.04e-03	25	79	2	EFO_0021120
Disease	PCSK9 protein measurement	ATXN7L1 KIAA1328	2.21e-03	26	79	2	EFO_0006899
Disease	serum alanine aminotransferase measurement	CELF6 JARID2 PRPF3 AHNAK MCM9 IQCN FNBP1L NLRP3	2.26e-03	869	79	8	EFO_0004735

Protein segments in the cluster

Peptide	Gene	Start	Entry
NASKQDGPMPKPHSV	VAPA	151	Q9P0L0
MANHDIPPDAVPNKK	TDRD5	446	Q8NAT2
PLLGMNPFQKNPKHA	EP400	2481	Q96L91
PGEFKMPKQLIHIQP	EPC1	91	Q9H2F5
KDVELSKMAPPDLPH	CDK12	1021	Q9NYV4
DFKHPDGIAVPVMLP	ALKBH8	261	Q96BT7
KKGMEPLQGHATPAL	CREBRF	276	Q8IUR6
PKISMPDVDLHLKGP	AHNAK	816	Q09666
PKISMPDVDLHLKGP	AHNAK	1651	Q09666
PKIPMPDFDLHLKGP	AHNAK	2961	Q09666
GMPDIKIEHPLDPNS	ANKRA2	26	Q9H9E1
KDKMQSPFAAPGPQH	DACH2	266	Q96NX9
NPAHNEGIIKPMKPL	CDH5	311	P33151
GLNPGPAVPMKDHDA	CELF6	31	Q96J87
ALLHMFSGKPPEKPL	FAM90A10	116	A6NDY2
AHPAGKMAPNPLLDT	ATG2A	406	Q2TAZ0
PGMNSVHKKNPPSLL	ATXN7L1	796	Q9ULK2
IEPPPGKHNDIDVFM	ADAMTS2	1106	O95450
PAPAHPSLLDKMEKA	IQCN	36	Q9H0B3
KMEKAPPQPQHEGLK	IQCN	46	Q9H0B3
KHKRPGEPNMQGIPK	INTS6	641	Q9UL03
PHDFGMKKPPLLNNA	PARP1	741	P09874
ALLHMFSGKPPEKPL	FAM90A7	116	A6NKC0
DLKRPMQAPPGHDQD	GOPC	261	Q9HD26
ALLHMFSGKPPEKPL	FAM90A23	116	A8MXZ1
HKMEQKENVPPGPEV	LIMA1	301	Q9UHB6
DQPPLDSLGMDHLPK	KIAA1755	1091	Q5JYT7
QVPPSHDAGLKDPMK	CCDC190	121	Q86UF4
NGKPLKNSMPHTLDP	FSIP2	801	Q5CZC0
GAMLKPHAPKLIPAL	ECPAS	1286	Q5VYK3
ALLHMFSGKPPEKPL	FAM90A22	116	A8MWA6
DNVTCMDLHKPPGPL	LTK	411	P29376
ALLHMFSGKPPEKPL	FAM90A14	116	P0C7W9
KPAAHFLPKPLEVAM	FGF14	191	Q92915
MPPLKSPAAFHEQIK	MRTFB	61	Q9ULH7
MKRKNEAPLILPPDH	KCNH1	721	O95259
LEKMHPKHQPLPESP	LRRC63	171	Q05C16
ALLHMFSGKPPEKPL	FAM90A17	116	P0DV74
DIPVMEGKKQPPRAH	KIAA1191	276	Q96A73
KLKLDVGEAMAPPSH	PELP1	496	Q8IZL8
ALLHMFSGKPPEKPL	FAM90A16	116	P0DV73
ALLHMFSGKPPEKPL	FAM90A19	116	P0DV76
PQEELHMKECPHLKP	KIAA1328	286	Q86T90
APMPKKTHQPSDEVG	POP1	746	Q99575
ALLHMFSGKPPEKPL	FAM90A8	116	A6NJQ4
HASKLMDKVELPPPD	COG6	421	Q9Y2V7
LKGNKPDFHLAMPTE	DTD1	86	Q8TEA8
KGPLKTPIAAGHPSM	IDH3A	96	P50213
VKMGPALEDFSHLPP	FNBP1L	386	Q5T0N5
PKPEMLDLHCDKIGP	CPLANE1	2726	Q9H799
PLIHKNMPPVAGQLK	DNAH17	576	Q9UFH2
MPNGQPPIKIFLEKH	FNIP1	471	Q8TF40
KRHKLANPPPMVEGE	ANK3	1026	Q12955
TAKMKPELLSGHIPP	MARVELD2	416	Q8N4S9
GKIKEEPPVAPHLME	KLHDC9	226	Q8NEP7
EHMKPSFLNPAKEPT	DDHD1	696	Q8NEL9
ALLHMFSGKPPEKPL	FAM90A20P	116	A6NIJ5
ALLHMFSGKPPEKPL	FAM90A5P	116	A8MXJ8
DHLMKVGKNNFRPPP	DIMT1	186	Q9UNQ2
HPGKKEMGTPLADTP	DPYSL5	501	Q9BPU6
ALLHMFSGKPPEKPL	FAM90A24P	116	P0C7X0
HAMGIAPPKVELKDQ	PRPF3	236	O43395
EAHQAEKPQSPPKKM	JARID2	446	Q92833
MPEDAKGQVKSQHPL	PHF20L1	136	A8MW92
GKLLGPLPMHPAAED	NUP88	291	Q99567
QPPEKHGPREKVMCA	MCM9	996	Q9NXL9
KMHLEDYPPQKGCIP	NLRP3	26	Q96P20
SEAKEPQKLPEHMNP	RTL3	56	Q8N8U3
ESKMSAGPHLPLKAP	SERF1A	46	O75920
PQPMKHLLHPTKGEP	ODAD4	161	Q96NG3
ALLHMFSGKPPEKPL	FAM90A12P	116	A8MX19
MASPHQEPKPGDLIE	PLAAT4	1	Q9UL19
ALLHMFSGKPPEKPL	FAM90A9	116	A6NNJ1
ALLHMFSGKPPEKPL	FAM90A13P	116	P0C7W8
TCMPEEGKILNPDHP	MED24	531	O75448
HPPMPALLQLKEKEA	NUDT12	251	Q9BQG2
SKQPFGMHPVLQEPK	POU4F3	6	Q15319
ALLHMFSGKPPEKPL	FAM90A15P	116	P0C7V4
FTPDHKPLMGEAPEL	SARDH	386	Q9UL12
DTAKGMLPDPKNVHI	SLC25A4	196	P12235
LPDAMKPHEIQEKLG	ARF6	126	P62330
LPLEGPKEEKVAMHA	C11orf16	316	Q9NQ32
KVKFHGEPQKPPMNG	UBTFL6	221	P0CB48
KIQPEMKTFPEAGPH	ZNF223	81	Q9UK11
QKHMKGHKPEEIPPD	ZBTB16	646	Q05516
KAPAAPLQAIFKHMP	RREB1	491	Q92766
MDLKEKHLGEPPSAL	TMEM94	1	Q12767
PEDKPKANSEHNGPM	HSPA4L	796	O95757
KGPPEIKIADMPLHS	TEX43	101	Q6ZNM6
KEHPSQGMKPTYLDP	PRLR	331	P16471
PPSKQKMIHELLDPN	PIEZO2	2511	Q9H5I5
PALHPMGLSLPKEKG	TRPV6	36	Q9H1D0
PLGDSHSLKKDPVMP	TEX13C	746	A0A0J9YWL9
GKTVAPMPPAQDHKR	GART	206	P22102
PHEAKPDKMAEAPPS	MAP2	371	P11137
QELPKLMDLHGKGPT	ZNF75D	346	P51815
KEKEPGMALPQGHLT	ZNF860	11	A6NHJ4
MKPPAHEEAKAPSRG	HDLBP	1211	Q00341
LHCKPAKPLPKEMEE	UGT2B15	281	P54855
LHCKPAKPLPKEMEE	UGT2B17	281	O75795
GLHCKPAKPLPKEME	UGT2A2	286	P0DTE5
PMDKKHPGIANLPEA	WDR64	766	B1ANS9
ALLHMFSGKPPEKPL	FAM90A18	116	P0DV75
LSKLKHQMAEPLPPE	GOLGA8CP	276	A6NN73
DGDPPLFDMHPVKTL	MYO3B	231	Q8WXR4
YKHGEKIPDMAPPQQ	MYOM2	1436	P54296