Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbeta-adrenergic receptor kinase activity

GRK5 GRK6

1.05e-054272GO:0047696
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK5 GRK6

3.68e-057272GO:0004703
GeneOntologyMolecularFunctionglutamate binding

CPS1 GCLC

1.59e-0414272GO:0016595
GeneOntologyMolecularFunctioncalcium ion binding

PITPNM2 CELSR1 CPS1 CELSR2 ITGB1 RPTN

4.11e-04749276GO:0005509
GeneOntologyMolecularFunctionprotein kinase binding

PITPNM2 PRKD2 PRKN TRIM21 ITGB1 GRK5

9.23e-04873276GO:0019901
GeneOntologyMolecularFunctionkinase binding

PITPNM2 PRKD2 PRKN TRIM21 ITGB1 GRK5

1.58e-03969276GO:0019900
GeneOntologyMolecularFunctionligase activity, forming carbon-nitrogen bonds

CPS1 GCLC

2.33e-0353272GO:0016879
GeneOntologyMolecularFunctionprotein kinase C binding

PRKD2 GRK5

3.58e-0366272GO:0005080
GeneOntologyMolecularFunctionamino acid binding

CPS1 GCLC

4.36e-0373272GO:0016597
GeneOntologyBiologicalProcessWnt signaling pathway

PRKN RSPO4 CELSR1 CELSR2 PRICKLE1 GRK5 GRK6

2.56e-06516267GO:0016055
GeneOntologyBiologicalProcesscellular response to fibroblast growth factor stimulus

PRKD2 CPS1 ITGB1 GCLC

1.68e-05124264GO:0044344
GeneOntologyBiologicalProcessresponse to fibroblast growth factor

PRKD2 CPS1 ITGB1 GCLC

2.15e-05132264GO:0071774
GeneOntologyBiologicalProcessregulation of spontaneous synaptic transmission

PRKN ITGB1

3.20e-057262GO:0150003
GeneOntologyBiologicalProcesspositive regulation of neurotransmitter uptake

PRKN ITGB1

3.20e-057262GO:0051582
GeneOntologyBiologicalProcessWnt signaling pathway, planar cell polarity pathway

CELSR1 CELSR2 PRICKLE1

4.47e-0555263GO:0060071
GeneOntologyBiologicalProcesspositive regulation of fibroblast growth factor receptor signaling pathway

PRKD2 ITGB1

8.35e-0511262GO:0045743
GeneOntologyBiologicalProcessnail development

RSPO4 PRICKLE1

8.35e-0511262GO:0035878
GeneOntologyBiologicalProcesscardiac muscle cell myoblast differentiation

PRICKLE1 ITGB1

1.00e-0412262GO:0060379
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway

CELSR1 CELSR2 PRICKLE1

1.22e-0477263GO:0035567
GeneOntologyBiologicalProcessprotein K27-linked ubiquitination

PRKN TRIM21

1.38e-0414262GO:0044314
GeneOntologyBiologicalProcessmotor neuron migration

CELSR1 CELSR2

1.59e-0415262GO:0097475
GeneOntologyBiologicalProcesspositive regulation of proteasomal ubiquitin-dependent protein catabolic process

PRKN PRICKLE1 GCLC

1.64e-0485263GO:0032436
GeneOntologyBiologicalProcessprotein K6-linked ubiquitination

PRKN TRIM21

2.05e-0417262GO:0085020
GeneOntologyBiologicalProcessmaintenance of postsynaptic specialization structure

PRICKLE1 ITGB1

2.05e-0417262GO:0098880
GeneOntologyBiologicalProcesscardioblast differentiation

PRICKLE1 ITGB1

2.31e-0418262GO:0010002
GeneOntologyBiologicalProcessspontaneous synaptic transmission

PRKN ITGB1

2.31e-0418262GO:0098814
GeneOntologyBiologicalProcessnegative regulation by host of viral process

PRKN PTX3

2.31e-0418262GO:0044793
GeneOntologyBiologicalProcessregulation of protein modification by small protein conjugation or removal

PRKN TRIM21 PRICKLE1 GCLC

3.47e-04271264GO:1903320
GeneOntologyBiologicalProcessregulation of post-translational protein modification

PRKN TRIM21 PRICKLE1 GCLC

3.77e-04277264GO:1901873
GeneOntologyBiologicalProcesspositive regulation of ubiquitin-dependent protein catabolic process

PRKN PRICKLE1 GCLC

3.90e-04114263GO:2000060
GeneOntologyBiologicalProcessregulation of neurotransmitter uptake

PRKN ITGB1

4.15e-0424262GO:0051580
GeneOntologyBiologicalProcesspositive regulation of proteasomal protein catabolic process

PRKN PRICKLE1 GCLC

4.87e-04123263GO:1901800
GeneOntologyBiologicalProcessdesensitization of G protein-coupled receptor signaling pathway

GRK5 GRK6

6.95e-0431262GO:0002029
GeneOntologyBiologicalProcessregulation of proteasomal ubiquitin-dependent protein catabolic process

PRKN PRICKLE1 GCLC

6.95e-04139263GO:0032434
GeneOntologyBiologicalProcessnegative adaptation of signaling pathway

GRK5 GRK6

7.40e-0432262GO:0022401
GeneOntologyBiologicalProcessadaptation of signaling pathway

GRK5 GRK6

7.40e-0432262GO:0023058
GeneOntologyBiologicalProcesspositive regulation of neurotransmitter transport

PRKN ITGB1

7.40e-0432262GO:0051590
GeneOntologyBiologicalProcesscell junction disassembly

PRICKLE1 ITGB1

7.88e-0433262GO:0150146
GeneOntologyBiologicalProcessviral life cycle

PRKN TRIM21 ITGB1 PTX3

8.14e-04340264GO:0019058
GeneOntologyBiologicalProcesspositive regulation of proteolysis involved in protein catabolic process

PRKN PRICKLE1 GCLC

8.34e-04148263GO:1903052
GeneOntologyBiologicalProcessbiological process involved in symbiotic interaction

PRKN TRIM21 ITGB1 PTX3

9.17e-04351264GO:0044403
GeneOntologyBiologicalProcessneurotransmitter reuptake

PRKN ITGB1

1.04e-0338262GO:0098810
GeneOntologyBiologicalProcesssulfur amino acid metabolic process

CPS1 GCLC

1.16e-0340262GO:0000096
GeneOntologyBiologicalProcessmaintenance of synapse structure

PRICKLE1 ITGB1

1.16e-0340262GO:0099558
GeneOntologyBiologicalProcessneutral lipid catabolic process

CPS1 ABHD16A

1.22e-0341262GO:0046461
GeneOntologyBiologicalProcessacylglycerol catabolic process

CPS1 ABHD16A

1.22e-0341262GO:0046464
GeneOntologyBiologicalProcesssymbiont entry into host cell

TRIM21 ITGB1 PTX3

1.22e-03169263GO:0046718
GeneOntologyBiologicalProcessbasement membrane organization

PRICKLE1 ITGB1

1.34e-0343262GO:0071711
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

PRKD2 CELSR1 TAS2R10 CELSR2 ITGB1 GRK5 GRK6

1.34e-031395267GO:0007186
GeneOntologyBiologicalProcesssymbiont entry into host

TRIM21 ITGB1 PTX3

1.37e-03176263GO:0044409
GeneOntologyBiologicalProcessregulation of fibroblast growth factor receptor signaling pathway

PRKD2 ITGB1

1.40e-0344262GO:0040036
GeneOntologyBiologicalProcessregulation of G protein-coupled receptor signaling pathway

ITGB1 GRK5 GRK6

1.49e-03181263GO:0008277
GeneOntologyBiologicalProcessregulation of ubiquitin-dependent protein catabolic process

PRKN PRICKLE1 GCLC

1.59e-03185263GO:2000058
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CELSR1 CELSR2 ITGB1

1.64e-03187263GO:0007156
GeneOntologyBiologicalProcesscellular response to glucose stimulus

PRKN PTPRN GCLC

1.87e-03196263GO:0071333
GeneOntologyBiologicalProcessneurotransmitter uptake

PRKN ITGB1

1.95e-0352262GO:0001504
GeneOntologyBiologicalProcessmodulation by host of viral process

PRKN PTX3

1.95e-0352262GO:0044788
GeneOntologyBiologicalProcesscellular response to hexose stimulus

PRKN PTPRN GCLC

1.95e-03199263GO:0071331
GeneOntologyBiologicalProcesscellular response to monosaccharide stimulus

PRKN PTPRN GCLC

2.01e-03201263GO:0071326
GeneOntologyBiologicalProcessblood vessel diameter maintenance

CPS1 ITGB1 GCLC

2.04e-03202263GO:0097746
GeneOntologyBiologicalProcessregulation of tube diameter

CPS1 ITGB1 GCLC

2.04e-03202263GO:0035296
GeneOntologyBiologicalProcessresponse to amino acid

PRKN CPS1 GCLC

2.04e-03202263GO:0043200
GeneOntologyBiologicalProcessregulation of tube size

CPS1 ITGB1 GCLC

2.07e-03203263GO:0035150
GeneOntologyBiologicalProcessprotein monoubiquitination

PRKN TRIM21

2.10e-0354262GO:0006513
GeneOntologyBiologicalProcessregulation of viral entry into host cell

TRIM21 PTX3

2.18e-0355262GO:0046596
GeneOntologyBiologicalProcessneuron projection extension

PRKN PRICKLE1 ITGB1

2.18e-03207263GO:1990138
GeneOntologyBiologicalProcessprotein destabilization

PRKN TRIM21

2.26e-0356262GO:0031648
GeneOntologyBiologicalProcessregulation of proteasomal protein catabolic process

PRKN PRICKLE1 GCLC

2.37e-03213263GO:0061136
GeneOntologyBiologicalProcesspostsynaptic density organization

PRICKLE1 ITGB1

2.42e-0358262GO:0097106
GeneOntologyBiologicalProcesscellular response to carbohydrate stimulus

PRKN PTPRN GCLC

2.43e-03215263GO:0071322
GeneOntologyBiologicalProcessintracellular glucose homeostasis

PRKN PTPRN GCLC

2.53e-03218263GO:0001678
GeneOntologyBiologicalProcessviral process

PRKN TRIM21 ITGB1 PTX3

2.55e-03464264GO:0016032
GeneOntologyBiologicalProcessmodulation by symbiont of entry into host

TRIM21 PTX3

2.76e-0362262GO:0052372
GeneOntologyBiologicalProcessregulation of protein ubiquitination

PRKN PRICKLE1 GCLC

2.80e-03226263GO:0031396
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process

PRKN PRICKLE1 GCLC

2.87e-03228263GO:0045732
GeneOntologyCellularComponentintegrin complex

ITGAD ITGB1

8.37e-0432282GO:0008305
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGAD ITGB1

2.82e-0359282GO:0098636
GeneOntologyCellularComponentSCF ubiquitin ligase complex

PRKN TRIM21

3.95e-0370282GO:0019005
MousePhenoincreased salivation

TRIM21 GRK5

8.47e-063242MP:0000622
DomainLIM3_prickle

PRICKLE1 PRICKLE3

6.50e-063282IPR033727
DomainLIM2_prickle

PRICKLE1 PRICKLE3

6.50e-063282IPR033726
DomainPET_prickle

PRICKLE1 PRICKLE3

6.50e-063282IPR033723
DomainPET

PRICKLE1 PRICKLE3

3.24e-056282PF06297
DomainPET

PRICKLE1 PRICKLE3

3.24e-056282PS51303
DomainPET_domain

PRICKLE1 PRICKLE3

3.24e-056282IPR010442
DomainGPCR_kinase

GRK5 GRK6

4.53e-057282IPR000239
DomainGAIN_dom_N

CELSR1 CELSR2

1.18e-0411282IPR032471
DomainGAIN

CELSR1 CELSR2

1.18e-0411282PF16489
DomainConA-like_dom

TRIM21 CELSR1 CELSR2 PTX3

3.02e-04219284IPR013320
Domain-

CELSR1 CELSR2 PTX3

3.81e-04952832.60.120.200
DomainIntegrin_dom

ITGAD ITGB1

6.36e-0425282IPR032695
DomainHormR

CELSR1 CELSR2

6.36e-0425282SM00008
DomainHRM

CELSR1 CELSR2

8.00e-0428282PF02793
DomainEGF_LAM_2

CELSR1 CELSR2

9.19e-0430282PS50027
DomainEGF_LAM_1

CELSR1 CELSR2

9.19e-0430282PS01248
DomainGPS

CELSR1 CELSR2

1.18e-0334282SM00303
DomainLaminin_EGF

CELSR1 CELSR2

1.25e-0335282PF00053
DomainGPS

CELSR1 CELSR2

1.25e-0335282PF01825
DomainRGS

GRK5 GRK6

1.25e-0335282PF00615
DomainRGS

GRK5 GRK6

1.25e-0335282SM00315
DomainEGF_Lam

CELSR1 CELSR2

1.25e-0335282SM00180
DomainRGS

GRK5 GRK6

1.32e-0336282PS50132
DomainGPS

CELSR1 CELSR2

1.32e-0336282PS50221
DomainGPS

CELSR1 CELSR2

1.40e-0337282IPR000203
DomainLAM_G_DOMAIN

CELSR1 CELSR2

1.47e-0338282PS50025
DomainLaminin_EGF

CELSR1 CELSR2

1.47e-0338282IPR002049
DomainRGS

GRK5 GRK6

1.55e-0339282IPR016137
DomainGrowth_fac_rcpt_

RSPO4 CELSR1 CELSR2

1.61e-03156283IPR009030
DomainG_PROTEIN_RECEP_F2_1

CELSR1 CELSR2

1.63e-0340282PS00649
DomainLaminin_G_2

CELSR1 CELSR2

1.63e-0340282PF02210
DomainG_PROTEIN_RECEP_F2_3

CELSR1 CELSR2

1.63e-0340282PS50227
DomainGPCR_2_extracellular_dom

CELSR1 CELSR2

1.63e-0340282IPR001879
DomainLamG

CELSR1 CELSR2

1.97e-0344282SM00282
DomainG_PROTEIN_RECEP_F2_2

CELSR1 CELSR2

2.54e-0350282PS00650
Domain7tm_2

CELSR1 CELSR2

2.54e-0350282PF00002
DomainAGC-kinase_C

GRK5 GRK6

3.17e-0356282IPR000961
DomainAGC_KINASE_CTER

GRK5 GRK6

3.17e-0356282PS51285
DomainS_TK_X

GRK5 GRK6

3.17e-0356282SM00133
DomainLaminin_G

CELSR1 CELSR2

3.40e-0358282IPR001791
DomainGPCR_2-like

CELSR1 CELSR2

3.64e-0360282IPR017981
DomainGPCR_2_secretin-like

CELSR1 CELSR2

3.64e-0360282IPR000832
DomainG_PROTEIN_RECEP_F2_4

CELSR1 CELSR2

3.76e-0361282PS50261
DomainLIM

PRICKLE1 PRICKLE3

4.78e-0369282PF00412
Domain-

PRICKLE1 PRICKLE3

4.91e-03702822.10.110.10
DomainLIM_DOMAIN_2

PRICKLE1 PRICKLE3

5.05e-0371282PS50023
DomainZnf_LIM

PRICKLE1 PRICKLE3

5.05e-0371282IPR001781
DomainLIM_DOMAIN_1

PRICKLE1 PRICKLE3

5.05e-0371282PS00478
DomainLIM

PRICKLE1 PRICKLE3

5.05e-0371282SM00132
DomainEGF

CELSR1 FCGBP CELSR2

5.11e-03235283SM00181
DomainEGF-like_dom

CELSR1 FCGBP CELSR2

6.00e-03249283IPR000742
DomainEGF_1

CELSR1 CELSR2 ITGB1

6.40e-03255283PS00022
DomainVWFA

ITGAD ITGB1

6.68e-0382282PS50234
DomainEGF-like_CS

CELSR1 CELSR2 ITGB1

6.83e-03261283IPR013032
PathwayREACTOME_REGULATION_OF_INNATE_IMMUNE_RESPONSES_TO_CYTOSOLIC_DNA

TRIM21 NLRP4

1.96e-0413232MM14931
PathwayREACTOME_REGULATION_OF_INNATE_IMMUNE_RESPONSES_TO_CYTOSOLIC_DNA

TRIM21 NLRP4

2.64e-0415232M27229
PathwayREACTOME_STING_MEDIATED_INDUCTION_OF_HOST_IMMUNE_RESPONSES

TRIM21 NLRP4

3.01e-0416232M27045
Pubmed

Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.

CELSR1 CELSR2 PRICKLE1

1.63e-08728317937400
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

CELSR1 CELSR2 PRICKLE1 PRICKLE3

5.85e-084728433141892
Pubmed

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.

RSPO4 CELSR1 CELSR2 PRICKLE1

2.06e-076428424431302
Pubmed

Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.

GRK5 GRK6

6.25e-07228217786238
Pubmed

Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation.

GRK5 GRK6

6.25e-07228220038610
Pubmed

Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.

CELSR1 CELSR2

6.25e-07228223292348
Pubmed

Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.

GRK5 GRK6

1.87e-0632827789183
Pubmed

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

GRK5 GRK6

1.87e-06328219801552
Pubmed

The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.

CELSR1 CELSR2

1.87e-06328211677057
Pubmed

Expression of G-protein-coupled receptor kinases in pregnant term and non-pregnant human myometrium.

GRK5 GRK6

1.87e-06328210467231
Pubmed

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

GRK5 GRK6

1.87e-06328212032308
Pubmed

Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).

GRK5 GRK6

1.87e-06328218662895
Pubmed

Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.

CELSR1 CELSR2 PRICKLE1

2.28e-063228323177622
Pubmed

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.

CELSR1 CELSR2

3.75e-06428237224017
Pubmed

G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.

GRK5 GRK6

3.75e-06428229969579
Pubmed

Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.

GRK5 GRK6

3.75e-06428221784156
Pubmed

Developmental expression profiles of Celsr (Flamingo) genes in the mouse.

CELSR1 CELSR2

3.75e-06428211850187
Pubmed

Phosphorylation and desensitization of the human thromboxane receptor-alpha by G protein-coupled receptor kinases.

GRK5 GRK6

3.75e-06428211504827
Pubmed

Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.

PRKD2 ITGB1

3.75e-06428222734003
Pubmed

The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis.

CELSR1 CELSR2 PRICKLE1

4.88e-064128330022023
Pubmed

c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes.

GRK5 GRK6

6.24e-06528227232975
Pubmed

Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines.

GRK5 GRK6

6.24e-06528212507501
Pubmed

Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity.

CELSR1 CELSR2

9.36e-06628236712970
Pubmed

beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress.

GRK5 GRK6

9.36e-06628220530803
Pubmed

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

GRK5 GRK6

9.36e-0662829826657
Pubmed

Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity.

GRK5 GRK6

9.36e-0662829211925
Pubmed

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.

GRK5 GRK6

9.36e-06628236451830
Pubmed

The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.

GRK5 GRK6

9.36e-06628210506199
Pubmed

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes.

GRK5 GRK6

9.36e-06628217060617
Pubmed

β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling.

GRK5 GRK6

9.36e-06628229627294
Pubmed

Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.

GRK5 GRK6

1.31e-0572828672451
Pubmed

Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.

GRK5 GRK6

1.31e-05728211517230
Pubmed

Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages.

GRK5 GRK6

2.24e-05928218180038
Pubmed

Synucleins are a novel class of substrates for G protein-coupled receptor kinases.

GRK5 GRK6

2.80e-051028210852916
Pubmed

Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data.

CPS1 GCLC

2.80e-051028220659789
Pubmed

A dual role for planar cell polarity genes in ciliated cells.

CELSR1 CELSR2

3.42e-051128225024228
Pubmed

Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.

CELSR1 CELSR2

4.10e-051228211891983
Pubmed

Microtubules enable the planar cell polarity of airway cilia.

CELSR1 PRICKLE1

4.10e-051228223122850
Pubmed

Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.

CELSR1 CELSR2

4.10e-051228220631168
Pubmed

Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development.

CELSR2 PRICKLE1

4.85e-051328221246654
Pubmed

A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.

CELSR1 CELSR2

4.85e-051328226989192
Pubmed

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels.

ITGAD ITGB1

4.85e-051328220563599
Pubmed

Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.

CELSR1 CELSR2

5.65e-051428239225402
Pubmed

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.

CELSR1 CELSR2

6.52e-051528220473291
Pubmed

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.

CELSR1 PRICKLE1

7.45e-051628222771245
Pubmed

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.

CELSR1 PRICKLE1

8.44e-051728228292423
Pubmed

Identification of Protor as a novel Rictor-binding component of mTOR complex-2.

CPS1 ABHD16A

1.18e-042028217461779
Pubmed

Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.

CELSR1 PRICKLE1

1.30e-042128218701545
Pubmed

USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.

CELSR1 PRICKLE1

1.43e-042228235440748
Pubmed

Primary cilia in murine palatal rugae development.

CELSR1 CELSR2

1.56e-042328231226309
Pubmed

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.

CELSR1 CELSR2

2.01e-042628237228654
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PITPNM2 PRKD2 CELSR1 CELSR2 GRK5 GRK6

2.10e-04110528635748872
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGAD ITGB1

2.17e-042728231541017
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

CELSR1 CELSR2

3.25e-043328225713288
InteractionMADD interactions

PRKN TRIM21 PTPRN GRK5

8.70e-0695284int:MADD
InteractionADGRG4 interactions

PRKN TRIM21

3.89e-057282int:ADGRG4
InteractionEEF1A1P5 interactions

PRKD2 PRKN TRIM21 FER1L6

4.13e-05141284int:EEF1A1P5
InteractionEFCAB5 interactions

PRKN TRIM21

5.19e-058282int:EFCAB5
InteractionSSX6P interactions

CELSR1 CELSR2

5.19e-058282int:SSX6P
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR2

4.24e-063222913
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR2

4.24e-0632221189
GeneFamilyPrickle planar cell polarity proteins|LIM domain containing

PRICKLE1 PRICKLE3

8.47e-0642221184
GeneFamilyLIM domain containing

PRICKLE1 PRICKLE3

2.32e-03592221218
CoexpressionGSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_DN

PRKD2 ITGB1 CD163L1 GRK6

1.70e-05146284M392
CoexpressionGSE3982_BASOPHIL_VS_TH2_UP

CELSR1 FCGBP ST3GAL6 PTX3

5.83e-05200284M5566
CoexpressionGSE17721_LPS_VS_CPG_16H_BMDC_DN

CELSR1 PRICKLE1 RPTN GRK5

5.83e-05200284M4009
CoexpressionKYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION

PRKD2 LDHD GCLC

7.57e-0577283M2540
CoexpressionSINGH_NFE2L2_TARGETS

GCLC GRK6

9.93e-0514282M2662
CoexpressionAtlasalpha beta T cells, T.8Mem.LN, CD8 TCRb CD44high CD122high, Lymph Node, avg-3

PITPNM2 PRKD2 CELSR1 ST3GAL6 GRK6

5.28e-05329275GSM538395_500
CoexpressionAtlasgamma delta T cells, Tgd.vg2+.Sp.TCRbko, TCRd+ Vg2+ CD44-, Spleen, avg-3

PITPNM2 PRKD2 CELSR1 ITGAD GRK6

1.15e-04388275GSM605790_500
CoexpressionAtlasgamma delta T cells, Tgd.vg2-.Sp.TCRbko, TCRd+ Vg2- CD44-, Spleen, avg-3

PITPNM2 PRKD2 CELSR1 ITGAD GRK6

1.41e-04405275GSM605796_500
ToppCellControl-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TAS2R10 FCGBP CELSR2

3.77e-051042835f72aa686b0fb83d401621e1b9d9c69e56105570
ToppCellControl-B_naive-4|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TAS2R10 FCGBP CELSR2

5.22e-0511628335d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Neuronal-Interneuron|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ST3GAL6 PRICKLE3 GRK5

6.52e-05125283eafc39072467e209c9fe3a4fa41cb09507a42e82
ToppCellAdult-Immune-enucleated_erythrocyte-D175|Adult / Lineage, Cell type, age group and donor

RSPO4 CELSR2 FER1L6

1.16e-04152283530d5427d8617dcb223d807b73abee0ef89285f3
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAS2R10 PTPRN GCLC

1.48e-041652834b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KBTBD12 CELSR2 GCLC

1.48e-041652830edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KBTBD12 CELSR2 GCLC

1.48e-04165283fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

CELSR1 FCGBP FER1L6

1.54e-041672836efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

ST3GAL6 GCLC CD163L1

1.56e-04168283bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

CELSR1 FCGBP CELSR2

1.62e-041702835a64e05c263df915085988d881808221e2c0f2e2
ToppCellfacs-Spleen-nan-24m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL6 PRICKLE1 ITGB1

1.71e-04173283e07e126e9dac6f1160cb3191d2e8374f39155d0d
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM21 GRK5 GRK6

1.71e-04173283c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM21 GRK5 GRK6

1.71e-04173283a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

CELSR1 ITGAD CD163L1

1.73e-041742834c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCellfacs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FCGBP ST3GAL6

1.76e-0417528321542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CELSR1 CELSR2 FER1L6

1.79e-041762838d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KBTBD12 ST3GAL6 FER1L6

1.79e-04176283cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

KBTBD12 ST3GAL6 PTPRN

1.82e-04177283e63d01c7fce4fa1256212fa7e95f74281edb3a01
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCGBP ITGAD CD163L1

1.82e-04177283945b2d0723a0a35c767604ae607d2c2d53bf0c82
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

KBTBD12 ST3GAL6 PTPRN

1.82e-041772830830944c43de300815831a9e2b2fce40965e7d12
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CELSR1 FCGBP FER1L6

1.82e-04177283779ba86f53650772755b52460be03f18bb204e55
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CELSR1 FCGBP FER1L6

1.82e-041772830f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

CELSR1 ITGAD CD163L1

1.82e-04177283470f54fe2b21c7350ea471e02039461a3808f700
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

CELSR1 FCGBP FER1L6

1.89e-041792831fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL6 GCLC CD163L1

1.92e-0418028381c7086399256260e59424b7410feec514ce8027
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CELSR1 FCGBP FER1L6

1.98e-041822833f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FCGBP RPTN FER1L6

2.01e-04183283514b72a1ae55656934839800513385e19bc240e2
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL6 GCLC CD163L1

2.01e-04183283302bd0f1f8025f385a764f2a9adafdd7f1f67ea3
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CELSR2 PTX3

2.01e-0418328399ab7a43527eb226027efbcd8c0b6a8e46fc3c93
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

CELSR1 FCGBP FER1L6

2.01e-04183283940cbe298e9c53b5622af09264586ed823d3141f
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CELSR2 PTX3

2.01e-0418328328916f0597690ff534578be2cb715b485cb1de1a
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST3GAL6 GCLC CD163L1

2.04e-04184283eeed75984ff111c0d1750df2f978163a42f20207
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST3GAL6 GCLC CD163L1

2.04e-041842833d8008f8d2e39c0d7a3cabc45620027491da03cf
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

KBTBD12 PRKN ST3GAL6

2.08e-04185283549eeb521c3985bff396ea0f202db21822efa51f
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 CELSR1 PRICKLE3

2.08e-04185283636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellBAL-Control-Myeloid-MoAM-MoAM5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCGBP ITGAD PTX3

2.14e-0418728359d28f4ee1d463ae20abb8d7e7399b504d80698a
ToppCellControl-Myeloid-MoAM5|Control / Disease group,lineage and cell class （2021.01.30）

FCGBP ITGAD PTX3

2.14e-041872838769341be67382cea2a590d962f4def7c39de883
ToppCellBAL-Control-Myeloid-MoAM-MoAM5-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCGBP ITGAD PTX3

2.14e-0418728325adf648c05c21534b4913254e73d43fc5f64e06
ToppCellBAL-Control-Myeloid-MoAM-MoAM5|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FCGBP ITGAD PTX3

2.14e-041872833b0cfa9e5ea5e7d6dda689c328b9b5110b43ee1d
ToppCellBAL-Control-Myeloid-MoAM-MoAM5-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FCGBP ITGAD PTX3

2.14e-041872830d589de12108230ced5b60229564f4a181e2f172
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD KBTBD12 PTPRN

2.18e-041882834db566f3f708e66730aa9e16f4d73d91dc534177
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD KBTBD12 PTPRN

2.18e-041882836704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCellwk_20-22-Hematologic-Myeloid-APOE+_Mac2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FCGBP ITGAD CD163L1

2.21e-04189283e189ef6066f87177d758f0e3ed9a17e01031a391
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 FCGBP CELSR2

2.21e-04189283ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 FCGBP CELSR2

2.21e-04189283dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD KBTBD12 PTPRN

2.28e-041912839d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD KBTBD12 PTPRN

2.28e-04191283543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellPND14-Endothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ST3GAL6 PRICKLE1 ITGB1

2.39e-04194283cee89d4340738f09d07a159cd6aeee4300776988
ToppCell3'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CD163L1 FER1L6

2.39e-041942831a188e52f2f0b6eca3e8d4a4671d9beab0fbbb88
ToppCellPND14-Endothelial-Endothelial_blood-vessel|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ST3GAL6 PRICKLE1 ITGB1

2.39e-0419428332962060d80f3edffbe9f0ecad3000c3a9817865
ToppCell3'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CD163L1 FER1L6

2.42e-041952833365768101454060b9ea96ef6b426c76c150bc8f
ToppCell10x5'v1-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KBTBD12 PRICKLE1 ABHD16A

2.42e-041952839b4f217325afb2efb9c65f298ac87649cb1e1af9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCLC RPTN FER1L6

2.50e-041972835c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

LDHD PRICKLE1 PRICKLE3

2.50e-041972838545baf923ddf84c5ce9414a36d810603be52401
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

PRKD2 TRIM21 ITGB1

2.54e-04198283ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CPS1 FER1L6

2.57e-04199283fb9550bbb1fa206c3132e0a21a646eedb41c281a
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CELSR1 PRICKLE1 GCLC

2.57e-0419928394a7867e800df352731796de8c24cba133c29622
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP GCLC FER1L6

2.57e-041992838bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP GCLC FER1L6

2.57e-041992830c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CPS1 FER1L6

2.57e-04199283440f47e320c75f49ef47139b46962de68cee8320
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 PRKD2 PRICKLE1

2.61e-04200283b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

PITPNM2 PRKD2 ITGB1

2.61e-04200283eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KBTBD12 PRICKLE3

3.97e-0447282b83e9a0f8db3f1581c5621f9d835ae2423ba0978
Diseasehydrocephalus (implicated_via_orthology)

CELSR2 ITGB1

1.37e-0419272DOID:10908 (implicated_via_orthology)
Diseaselipoprotein A measurement

PRKN CPS1 CELSR2

1.46e-04112273EFO_0006925
Diseaseaspartate measurement

CPS1 GRK6

2.20e-0424272EFO_0010462
Diseasecalcium measurement

PITPNM2 CPS1 CELSR2 PRICKLE3 GRK5

2.35e-04628275EFO_0004838
Diseasecystic fibrosis (is_implicated_in)

GCLC PTX3

2.79e-0427272DOID:1485 (is_implicated_in)
DiseaseL-arginine measurement

CPS1 GRK6

2.79e-0427272EFO_0006524
DiseaseParkinson's disease (biomarker_via_orthology)

GRK5 GRK6

3.45e-0430272DOID:14330 (biomarker_via_orthology)
Diseasepyridoxate measurement

ABHD16A GRK5

3.69e-0431272EFO_0010527
DiseaseGastric Adenocarcinoma

PRKD2 GRK6

7.79e-0445272C0278701
Diseasetryptophan measurement

PRKD2 GRK5

9.23e-0449272EFO_0008534
Diseasemonoclonal gammopathy

PRKN CPS1

1.08e-0353272EFO_0000203
Diseasephenylalanine measurement

CPS1 GRK6

1.16e-0355272EFO_0005001
Diseaseceramide measurement

PRKN CPS1 CELSR2

1.27e-03235273EFO_0010222
Diseasehistidine measurement

CPS1 GRK6

1.67e-0366272EFO_0009769
Diseasevenous thromboembolism, fibrinogen measurement

CPS1 GRK5

1.72e-0367272EFO_0004286, EFO_0004623
DiseaseParkinson's disease (is_marker_for)

PRKN GRK5

1.72e-0367272DOID:14330 (is_marker_for)
Diseasemean platelet volume

PITPNM2 CPS1 ST3GAL6 PRICKLE3 GRK5

2.09e-031020275EFO_0004584
Diseasestem Cell Growth Factor beta measurement

PRKN GRK6

2.15e-0375272EFO_0008292
DiseaseParkinson's disease (is_implicated_in)

PRKN GRK6

2.20e-0376272DOID:14330 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
PQGQKLVICCEGNAG

ABHD16A

276

O95870
VCKNGGTCVNLLIGG

CELSR1

1411

Q9NYQ6
VCKNGGTCVNLLVGG

CELSR2

1336

Q9HCU4
IAGIVCRQLGCGENG

CD163L1

1176

Q9NR16
DRSNGLICGGNGVCK

ITGB1

561

P05556
EVCIQDGLFGQCQVG

PTPRN

51

Q16849
CKGGNAVVDGCGKAQ

GCLC

491

P48506
GLVRQGLKCDGCGLN

PRKD2

161

Q9BZL6
IGCNEIGDVGVQLLC

NLRP4

871

Q96MN2
FNGQVCLIGDCVGGI

PITPNM2

551

Q9BZ72
KNCGQDGLCEGDLGV

ITGAD

766

Q13349
ENKVVADLGCGCGVL

METTL5

51

Q9NRN9
CEQCGLKINGGEVAV

PRICKLE1

126

Q96MT3
ITGAICEECGKQIGG

PRICKLE3

181

O43900
QEACGGCIISVGGQI

CPS1

1046

P31327
AGQRCQVVGGKAGCV

FCGBP

451

Q9Y6R7
ETCKEQGGQGVCLPN

FCGBP

4056

Q9Y6R7
LEGGVCAVQGGVCVN

LDHD

101

Q86WU2
VLGKGGFGEVCACQV

GRK5

191

P34947
VLGKGGFGEVCACQV

GRK6

191

P43250
GILQIGQEKNGCCVG

PTX3

306

P26022
GCVGQDKGQVRKCLD

KBTBD12

501

Q3ZCT8
QALIECGGQGVKSCV

FER1L6

1016

Q2WGJ9
VLGNGFIGLVNCIDC

TAS2R10

21

Q9NYW0
QVGTGLGGNCTGCII

RSPO4

26

Q2I0M5
DQRKVTCEGGNGLGC

PRKN

346

O60260
DNIPCKKCVVVGNGG

ST3GAL6

111

Q9Y274
CQECISQVGKGGGSV

TRIM21

36

P19474
CGQSERLGQELGCGQ

RPTN

271

Q6XPR3