Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coregulator activity	KMT2C SIN3B MTA1 ATN1 IRF2BP1 DTX1 BRD4 SMARCC1 KDM7A SIRT6 KMT2E MED26 SPEN MIDEAS	3.86e-08	562	79	14	GO:0003712
GeneOntologyMolecularFunction	molecular adaptor activity	KMT2C SIN3B MTA1 ATN1 ANK3 IRF2BP1 DTX1 BRD4 KSR2 SMARCC1 LTBP1 KDM7A SIRT6 KMT2E MED26 SPEN MIDEAS ADAM10 NLRP3	9.89e-07	1356	79	19	GO:0060090
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	KMT2C SIN3B MTA1 ATN1 ANK3 IRF2BP1 DTX1 BRD4 KSR2 SMARCC1 KDM7A SIRT6 KMT2E MED26 SPEN MIDEAS NLRP3	2.26e-06	1160	79	17	GO:0030674
GeneOntologyMolecularFunction	transcription coactivator activity	KMT2C MTA1 ATN1 DTX1 BRD4 SMARCC1 KMT2E MED26	2.63e-05	303	79	8	GO:0003713
GeneOntologyMolecularFunction	transcription corepressor activity	SIN3B MTA1 ATN1 IRF2BP1 SIRT6 SPEN MIDEAS	3.42e-05	229	79	7	GO:0003714
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2C SETBP1 KMT2E	7.02e-04	44	79	3	GO:0140938
GeneOntologyCellularComponent	postsynaptic specialization	USP8 ARHGAP32 NEO1 ANK3 ABI3BP PCLO LRRTM3 PRRT2 ADAM10 CHRNA4	1.94e-05	503	79	10	GO:0099572
GeneOntologyCellularComponent	postsynaptic density	USP8 ARHGAP32 NEO1 ANK3 ABI3BP PCLO LRRTM3 PRRT2 ADAM10	5.06e-05	451	79	9	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	USP8 ARHGAP32 NEO1 ANK3 ABI3BP PCLO LRRTM3 PRRT2 ADAM10	7.77e-05	477	79	9	GO:0032279
GeneOntologyCellularComponent	dendrite	CACNA1B USP8 ARHGAP32 ANK3 ABI3BP PCLO EIF4B LTBP1 PRRT2 ADAM10 CHRNA4 CRMP1	8.62e-05	858	79	12	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNA1B USP8 ARHGAP32 ANK3 ABI3BP PCLO EIF4B LTBP1 PRRT2 ADAM10 CHRNA4 CRMP1	8.82e-05	860	79	12	GO:0097447
GeneOntologyCellularComponent	neuron to neuron synapse	USP8 ARHGAP32 NEO1 ANK3 ABI3BP PCLO LRRTM3 PRRT2 ADAM10	1.56e-04	523	79	9	GO:0098984
GeneOntologyCellularComponent	histone deacetylase complex	SIN3B MTA1 KMT2E MIDEAS	3.03e-04	85	79	4	GO:0000118
GeneOntologyCellularComponent	somatodendritic compartment	CACNA1B USP8 ARHGAP32 NEO1 ANK3 ABI3BP PCLO EIF4B LTBP1 PRRT2 ADAM10 CHRNA4 CRMP1	6.55e-04	1228	79	13	GO:0036477
HumanPheno	Inheritance qualifier	STK11 KMT2C ATN1 ATXN7 DCHS1 SMARCC1 CILK1 PRRT2 CHRNA4	1.46e-05	330	25	9	HP:0034335
HumanPheno	Recurrent maladaptive behavior	CACNA1B KMT2C USP8 SIN3B ANK3 ATXN7 BRD4 SETBP1 DCHS1 ANKRD11 CILK1 PRRT2 KMT2E SPEN CHRNA4 NLRP3	5.03e-05	1293	25	16	HP:5200241
HumanPheno	Abnormally increased volition	CACNA1B KMT2C ANK3 ATXN7 BRD4 SETBP1 DCHS1 ANKRD11 CILK1 PRRT2 KMT2E SPEN CHRNA4	6.56e-05	869	25	13	HP:5200263
HumanPheno	Aggressive behavior	CACNA1B KMT2C ANK3 BRD4 SETBP1 DCHS1 CILK1 PRRT2 KMT2E SPEN	8.34e-05	516	25	10	HP:0000718
HumanPheno	Abnormal aggressive, impulsive or violent behavior	CACNA1B KMT2C ANK3 BRD4 SETBP1 DCHS1 CILK1 PRRT2 KMT2E SPEN	8.34e-05	516	25	10	HP:0006919
HumanPheno	Reduced impulse control	CACNA1B KMT2C ANK3 ATXN7 BRD4 SETBP1 DCHS1 ANKRD11 CILK1 PRRT2 KMT2E SPEN CHRNA4 NLRP3	8.45e-05	1032	25	14	HP:5200045
HumanPheno	Disinhibition	CACNA1B KMT2C ANK3 BRD4 SETBP1 DCHS1 ANKRD11 CILK1 PRRT2 KMT2E SPEN CHRNA4	1.62e-04	807	25	12	HP:0000734
HumanPheno	Inappropriate behavior	CACNA1B KMT2C ANK3 BRD4 SETBP1 DCHS1 ANKRD11 CILK1 PRRT2 KMT2E SPEN CHRNA4	1.62e-04	807	25	12	HP:0000719
HumanPheno	Abnormal response to social norms	CACNA1B KMT2C ANK3 BRD4 SETBP1 DCHS1 ANKRD11 CILK1 PRRT2 KMT2E SPEN CHRNA4	1.62e-04	807	25	12	HP:5200123
HumanPheno	Social disinhibition	CACNA1B KMT2C ANK3 BRD4 SETBP1 DCHS1 ANKRD11 CILK1 PRRT2 KMT2E SPEN CHRNA4	1.62e-04	807	25	12	HP:5200029
MousePheno	lethality during fetal growth through weaning, complete penetrance	STK11 SP2 KMT2C SIN3B OLIG3 NEO1 WIZ ANK3 TULP4 ZIC5 EIF4B DCHS1 CILK1 LTBP1 KMT2E SPEN MIDEAS CHRNA4 NLRP3	6.18e-06	1269	68	19	MP:0011111
MousePheno	enlarged stomach	STK11 ANKRD20A4P ANKRD20A3P ANKRD20A1	1.88e-05	33	68	4	MP:0003883
MousePheno	abnormal axial skeleton morphology	MTA1 WIZ ANKRD20A4P ABI3BP TULP4 ZIC5 ATXN7 BRD4 COBLL1 DCHS1 ANKRD11 CILK1 LTBP1 KDM7A ANKRD20A3P RELT SIRT6 ST18 ANKRD20A1	4.44e-05	1458	68	19	MP:0002114
Domain	Ankyrin_rpt	FANK1 ANKRD20A4P ANK3 RAPH1 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	1.63e-05	262	80	8	IPR002110
Domain	Ank_2	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	3.79e-05	215	80	7	PF12796
Domain	Ank	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	5.49e-05	228	80	7	PF00023
Domain	-	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	9.31e-05	248	80	7	1.25.40.20
Domain	ANK	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	1.00e-04	251	80	7	SM00248
Domain	ANK_REPEAT	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	1.05e-04	253	80	7	PS50088
Domain	Ankyrin_rpt-contain_dom	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	1.08e-04	254	80	7	IPR020683
Domain	ANK_REP_REGION	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	1.08e-04	254	80	7	PS50297
Domain	SPOC	SPOCD1 SPEN	1.08e-04	4	80	2	PS50917
Domain	SCA7	ATXN7 ATXN7L1	1.08e-04	4	80	2	PF08313
Domain	WWE	DTX1 DTX4	1.08e-04	4	80	2	SM00678
Domain	WWE-dom_subgr	DTX1 DTX4	1.08e-04	4	80	2	IPR018123
Domain	SCA7	ATXN7 ATXN7L1	1.08e-04	4	80	2	PS51505
Domain	SCA7_dom	ATXN7 ATXN7L1	1.08e-04	4	80	2	IPR013243
Domain	SANT_dom	MTA1 SMARCC1 MIDEAS	1.83e-04	26	80	3	IPR017884
Domain	SANT	MTA1 SMARCC1 MIDEAS	2.29e-04	28	80	3	PS51293
Domain	SPOC_C	SPOCD1 SPEN	2.69e-04	6	80	2	IPR012921
Domain	SPOC	SPOCD1 SPEN	2.69e-04	6	80	2	PF07744
Domain	Myb_DNA-binding	MTA1 SMARCC1 MIDEAS	4.49e-04	35	80	3	PF00249
Domain	MYB_LIKE	MTA1 SMARCC1 MIDEAS	5.73e-04	38	80	3	PS50090
Domain	MYTH4	PLEKHH2 MYO15A	6.40e-04	9	80	2	PS51016
Domain	MyTH4_dom	PLEKHH2 MYO15A	6.40e-04	9	80	2	IPR000857
Domain	MyTH4	PLEKHH2 MYO15A	6.40e-04	9	80	2	PF00784
Domain	MyTH4	PLEKHH2 MYO15A	6.40e-04	9	80	2	SM00139
Domain	EH	SYNRG EHD4	9.72e-04	11	80	2	PS50031
Domain	EH	SYNRG EHD4	9.72e-04	11	80	2	SM00027
Domain	EH_dom	SYNRG EHD4	9.72e-04	11	80	2	IPR000261
Domain	WWE	DTX1 DTX4	1.16e-03	12	80	2	PS50918
Domain	WWE	DTX1 DTX4	1.16e-03	12	80	2	PF02825
Domain	WWE-dom	DTX1 DTX4	1.16e-03	12	80	2	IPR004170
Domain	SANT	MTA1 SMARCC1 MIDEAS	1.28e-03	50	80	3	SM00717
Domain	ELM2	MTA1 MIDEAS	1.37e-03	13	80	2	PF01448
Domain	ELM2	MTA1 MIDEAS	1.37e-03	13	80	2	PS51156
Domain	ELM2_dom	MTA1 MIDEAS	1.37e-03	13	80	2	IPR000949
Domain	ELM2	MTA1 MIDEAS	1.37e-03	13	80	2	SM01189
Domain	SANT/Myb	MTA1 SMARCC1 MIDEAS	1.44e-03	52	80	3	IPR001005
Domain	AT_hook	KMT2C SETBP1	2.09e-03	16	80	2	PF02178
Domain	-	KMT2C DTX1 DTX4 PCLO PRPF19 KDM7A KMT2E	3.11e-03	449	80	7	3.30.40.10
Domain	Znf_RING/FYVE/PHD	KMT2C DTX1 DTX4 PCLO PRPF19 KDM7A KMT2E	3.51e-03	459	80	7	IPR013083
Domain	Znf_FYVE_PHD	KMT2C PCLO KDM7A KMT2E	3.67e-03	147	80	4	IPR011011
Domain	PHD	KMT2C KDM7A KMT2E	4.09e-03	75	80	3	PF00628
Domain	Znf_PHD-finger	KMT2C KDM7A KMT2E	4.74e-03	79	80	3	IPR019787
Domain	AT_hook	KMT2C SETBP1	5.93e-03	27	80	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2C SETBP1	5.93e-03	27	80	2	IPR017956
Domain	PHD	KMT2C KDM7A KMT2E	6.60e-03	89	80	3	SM00249
Domain	Znf_PHD	KMT2C KDM7A KMT2E	7.01e-03	91	80	3	IPR001965
Domain	HMGI/Y_DNA-bd_CS	KMT2C SETBP1	7.77e-03	31	80	2	IPR000637
Domain	ZF_PHD_2	KMT2C KDM7A KMT2E	7.89e-03	95	80	3	PS50016
Domain	ZF_PHD_1	KMT2C KDM7A KMT2E	8.12e-03	96	80	3	PS01359
Pubmed	Human transcription factor protein interaction networks.	SP2 KMT2C SIN3B ARHGAP32 MTA1 WIZ ATN1 SMG7 IRF2BP1 ATXN7 ATXN7L1 ZNF629 SMARCC1 PRPF19 PROSER1 MBD6 SPEN MIDEAS	5.91e-09	1429	83	18	35140242
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SYNRG KMT2C SIN3B WIZ SMG7 ANK3 RAPH1 BRD4 SMARCC1 SPEN MIDEAS	7.95e-08	549	83	11	38280479
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ARHGAP32 MTA1 ATN1 ANK3 TULP4 DTX1 SETBP1 KMT2E SPEN FAM110B	8.19e-08	430	83	10	35044719
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PPP1R26 SP2 SIN3B ARHGAP32 TULP4 COBLL1 ZNF629 CILK1 PLEKHH2 POM121B	2.89e-07	493	83	10	15368895
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A4P ANKRD20A3P ANKRD20A1	7.28e-07	8	83	3	12634303
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SYNRG USP8 ARHGAP32 RAPH1 CLMN BRD4 COBLL1 EIF4B ZNF629 ANKRD11 RAB11FIP5 FAM110B	9.50e-07	861	83	12	36931259
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2C WIZ ATN1 SMARCC1 PROSER1 MBD6 SPEN MIDEAS	2.03e-06	351	83	8	38297188
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PPP1R26 SYNRG KMT2C WIZ TULP4 BRD4 KSR2 ANKRD11 DISP2 SFI1 MBD6 SPEN CNTROB	2.11e-06	1105	83	13	35748872
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	KMT2C MTA1 WIZ SMARCC1 MED26 MIDEAS	3.11e-06	167	83	6	20362541
Pubmed	Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.	SIN3B MTA1 WIZ MIDEAS	4.17e-06	45	83	4	21258344
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	MTA1 WIZ BRD4 SMARCC1 SPEN	4.99e-06	103	83	5	32744500
Pubmed	Normal immune system development in mice lacking the Deltex-1 RING finger domain.	DTX1 DTX4	5.63e-06	2	83	2	15684394
Pubmed	USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy.	NLRP3 USP19	5.63e-06	2	83	2	33097834
Pubmed	Liver kinase B1 attenuates liver ischemia/reperfusion injury via inhibiting the NLRP3 inflammasome.	STK11 NLRP3	5.63e-06	2	83	2	33783473
Pubmed	Smooth muscle liver kinase B1 inhibits foam cell formation and atherosclerosis via direct phosphorylation and activation of SIRT6.	STK11 SIRT6	5.63e-06	2	83	2	37607939
Pubmed	ADAM10 Cell Surface Expression but Not Activity Is Critical for Staphylococcus aureus α-Hemolysin-Mediated Activation of the NLRP3 Inflammasome in Human Monocytes.	ADAM10 NLRP3	5.63e-06	2	83	2	27043625
Pubmed	BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis.	BRD4 NLRP3	5.63e-06	2	83	2	35154163
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	SIN3B MTA1 WIZ IRF2BP1 ZIC5 EIF4B ZNF629 SMARCC1 PRPF19	1.07e-05	583	83	9	29844126
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SP2 KMT2C SIN3B MTA1 WIZ ZIC5 BRD4 ZNF629 ANKRD11 SMARCC1 PRPF19 SPEN MIDEAS	1.16e-05	1294	83	13	30804502
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	KMT2C SIN3B MTA1 WIZ IRF2BP1 BRD4 EIF4B ZNF629 SMARCC1 PRPF19 SPEN MIDEAS	1.19e-05	1103	83	12	34189442
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	EPHX1 USP8 WIZ IRF2BP1 EIF4B DCHS1 SMARCC1 PLEKHH2 CNTROB CRMP1	1.26e-05	754	83	10	35906200
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	KMT2C MTA1 WIZ SMARCC1 PRPF19 MIDEAS	1.51e-05	220	83	6	35785414
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SYNRG MTA1 ATN1 RAPH1 ATXN7 BRD4 EIF4B SMARCC1 SPEN USP19	1.58e-05	774	83	10	15302935
Pubmed	Ligand-activated Notch undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing.	DTX4 ADAM10	1.69e-05	3	83	2	28611181
Pubmed	T cells develop normally in the absence of both Deltex1 and Deltex2.	DTX1 DTX4	1.69e-05	3	83	2	16923970
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2C KDM7A KMT2E	1.69e-05	21	83	3	27626377
Pubmed	Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.	STK11 EIF4B	3.37e-05	4	83	2	12489981
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	SIN3B WIZ ATN1 BRD4 SMARCC1 MIDEAS	4.55e-05	268	83	6	33640491
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	SP2 KMT2C WIZ BRD4 PCLO SMARCC1 MYO15A	4.79e-05	398	83	7	35016035
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	WIZ SMARCC1 SPEN MIDEAS	4.80e-05	83	83	4	28794006
Pubmed	Molecular analysis of CAG repeats at five different spinocerebellar ataxia loci: correlation and alternative explanations for disease pathogenesis.	ATN1 ATXN7	5.60e-05	5	83	2	18182848
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	USP8 ARHGAP32 ANK3 RAPH1 CLMN COBLL1 EIF4B EHD4	6.26e-05	565	83	8	25468996
Pubmed	Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.	ATXN7 ATXN7L1	8.39e-05	6	83	2	15115762
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	SP2 SYNRG MTA1 ATXN7 EIF4B RAB11FIP5 MED26	9.50e-05	444	83	7	34795231
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DTX4 COBLL1 CILK1 SPEN	1.07e-04	102	83	4	10231032
Pubmed	Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways.	STK11 MTA1	1.17e-04	7	83	2	22270359
Pubmed	The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis.	OLIG3 MED26	1.17e-04	7	83	2	19362612
Pubmed	Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.	SMARCC1 MED26	1.17e-04	7	83	2	20111005
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2C KMT2E	1.56e-04	8	83	2	23130995
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	STK11 USP8 ABI3BP RAPH1 ATXN7 PCLO EIF4B SMARCC1 PRPF19 NDUFA7 SPEN EHD4	1.57e-04	1442	83	12	35575683
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	SIN3B MTA1 ATXN7 BRD4 PRPF19 SPEN	1.65e-04	339	83	6	30415952
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP32 WIZ SMG7 ANK3 RAPH1 RAB11FIP5 PRPF19 LTBP1 CNTROB EHD4	1.98e-04	1049	83	10	27880917
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KMT2C SMG7 ANK3 TULP4 ATXN7 ATXN7L1 CLMN SETBP1 KSR2 ANKRD11 CILK1 LRRC8D	2.11e-04	1489	83	12	28611215
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KMT2C KDM7A KMT2E	2.23e-04	49	83	3	34368113
Pubmed	Screening for premutation in the FMR1 gene in male patients suspected of spinocerebellar ataxia.	ATN1 ATXN7	2.50e-04	10	83	2	19235102
Pubmed	HIV-1 Vif promotes the G₁- to S-phase cell-cycle transition.	BRD4 PRPF19	2.50e-04	10	83	2	21149631
Pubmed	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	ANK3 PCLO	3.05e-04	11	83	2	20351715
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	SIN3B WIZ BRD4 SPEN	3.06e-04	134	83	4	25452129
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	KMT2C SIN3B SMG7 BRD4 EIF4B ZNF629 ANKRD11 SMARCC1 LTBP1 USP19 CRMP1	3.12e-04	1327	83	11	32694731
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MTA1 WIZ ATN1 SMG7 ATXN7 ATXN7L1 BRD4 ZNF629 SMARCC1 RAB11FIP5	3.24e-04	1116	83	10	31753913
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SYNRG MTA1 WIZ SMG7 EIF4B ZNF629 SMARCC1 SPEN	3.39e-04	724	83	8	36232890
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SYNRG USP8 SIN3B WIZ SMG7 RAPH1 CLMN EIF4B PRPF19	3.89e-04	934	83	9	33916271
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	SIN3B MTA1 SMARCC1 PRPF19 LTBP1	3.99e-04	259	83	5	31162944
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	KMT2C MTA1 WIZ MIDEAS	4.23e-04	146	83	4	23892456
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	SIN3B ARHGAP32 SMG7 ANK3 RAB11FIP5	4.27e-04	263	83	5	34702444
Pubmed	Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.	MTA1 COBLL1	4.31e-04	13	83	2	22294699
Pubmed	Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.	KMT2C PROSER1	4.31e-04	13	83	2	17761849
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP8 FCHSD2 DISP2 SPEN ST18 USP19	4.37e-04	407	83	6	12693553
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	KMT2C FANK1 ABI3BP CILK1 FAM110B	4.42e-04	265	83	5	19240061
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	MTA1 WIZ BRD4 EIF4B ANKRD11 SMARCC1 PRPF19 SPEN MIDEAS	4.53e-04	954	83	9	36373674
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	MTA1 WIZ BRD4 SMARCC1 PRPF19 PROSER1	4.61e-04	411	83	6	35182466
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	CACNA1B PCLO	5.03e-04	14	83	2	21228161
Pubmed	Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.	SIN3B MTA1	5.03e-04	14	83	2	20585571
Pubmed	A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.	STK11 BRD4 SMARCC1	5.14e-04	65	83	3	27453043
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	WIZ ATN1 PCLO SMARCC1 PROSER1 MED26	5.49e-04	425	83	6	24999758
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	MTA1 ANKRD11 SMARCC1 MBD6	5.57e-04	157	83	4	30186101
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	SP2 SIN3B MTA1 IRF2BP1 SPEN	5.86e-04	282	83	5	23667531
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	ARHGAP32 ATN1 ATXN7 LTBP1 MBD6 SPEN CNTROB	6.35e-04	608	83	7	16713569
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SIN3B MTA1 WIZ BRD4 SMARCC1 SPEN MIDEAS	6.35e-04	608	83	7	36089195
Pubmed	The functional interactome landscape of the human histone deacetylase family.	SIN3B MTA1 ANKRD11 SMARCC1 MIDEAS	6.55e-04	289	83	5	23752268
Pubmed	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?	SIN3B SMARCC1	6.61e-04	16	83	2	16787967
Pubmed	Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.	CACNA1B CRMP1	6.61e-04	16	83	2	17444492
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL24A1 ABI3BP LTBP1 ADAM10	7.01e-04	167	83	4	22159717
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	COL24A1 MTA1 RAPH1 CRACDL LTBP1 KDM7A PRRT2 MYO15A LRRC8D ST18	7.44e-04	1242	83	10	30973865
Pubmed	Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.	ATN1 ATXN7	7.48e-04	17	83	2	15148151
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	SIN3B MTA1 BRD4	7.82e-04	75	83	3	25593309
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	KMT2C ATN1 SMG7 IRF2BP1 SMARCC1 MIDEAS	8.01e-04	457	83	6	32344865
Pubmed	mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.	SIN3B SMARCC1	8.40e-04	18	83	2	14559996
Pubmed	An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse.	WIZ SMARCC1	8.40e-04	18	83	2	24025402
Pubmed	Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.	SIN3B MTA1	8.40e-04	18	83	2	10444591
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	USP8 ARHGAP32 IRF2BP1 ATXN7 SMARCC1 RAB11FIP5 SPEN	8.42e-04	638	83	7	31182584
Pubmed	Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.	SIN3B WIZ MIDEAS	8.44e-04	77	83	3	19505873
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KMT2C MTA1 BRD4 SMARCC1 SPEN CNTROB	9.16e-04	469	83	6	27634302
Pubmed	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	ATXN7L1 CILK1 KMT2E ADAM10	9.27e-04	180	83	4	24104479
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	PPP1R26 SFI1 SPOCD1	9.43e-04	80	83	3	19389623
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	SMG7 IRF2BP1 SPEN CNTROB	1.01e-03	184	83	4	32908313
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	SP2 MTA1 WIZ EIF4B PRPF19	1.05e-03	321	83	5	32098917
Pubmed	The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.	SIN3B PRPF19 SPEN	1.09e-03	84	83	3	26299517
Pubmed	A human MAP kinase interactome.	KMT2C ARHGAP32 ANK3 ABI3BP COBLL1 MIDEAS	1.10e-03	486	83	6	20936779
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TULP4 DTX1 BRD4 SMARCC1 SPEN	1.17e-03	329	83	5	17474147
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	KMT2C SIN3B MTA1 WIZ ATN1 MBD6	1.21e-03	495	83	6	27705803
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2C KMT2E	1.26e-03	22	83	2	26886794
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MTA1 WIZ RAPH1 BRD4 COBLL1 SMARCC1	1.35e-03	506	83	6	30890647
Pubmed	The Repeat Expansion Diseases: The dark side of DNA repair.	ATN1 ATXN7	1.38e-03	23	83	2	26002199
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	NEO1 PCLO NDUFA7 ADAM10	1.42e-03	202	83	4	33601422
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	BRD4 SMARCC1 SIRT6 EHD4	1.44e-03	203	83	4	22083510
Pubmed	PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.	ANK3 RAPH1 ADAM10	1.50e-03	94	83	3	32062451
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SP2 KMT2C SIN3B OLIG3 MTA1 BRD4 SMARCC1	1.55e-03	709	83	7	22988430
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	PPP1R26 STK11 ZIC5 EIF4B ANKRD11 SMARCC1 RAB11FIP5 PRPF19	1.62e-03	922	83	8	27609421
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KMT2C SMG7 SETBP1 RAB11FIP5 KDM7A SFI1	1.69e-03	529	83	6	14621295
Interaction	CRX interactions	KMT2C WIZ ATN1 ATXN7 SMARCC1 PROSER1 SFI1 SPEN MIDEAS	1.02e-06	254	83	9	int:CRX
Interaction	ANKRD20A4P interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	1.34e-06	6	83	3	int:ANKRD20A4P
Interaction	ANKRD20A2P interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	2.33e-06	7	83	3	int:ANKRD20A2P
Interaction	EGR2 interactions	KMT2C WIZ ATN1 DTX1 SMARCC1 PROSER1 MIDEAS	6.76e-06	171	83	7	int:EGR2
Interaction	TBXT interactions	KMT2C WIZ ATN1 SMARCC1 SPEN MIDEAS	8.40e-06	116	83	6	int:TBXT
Interaction	ANKRD20A1 interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	1.09e-05	11	83	3	int:ANKRD20A1
Interaction	HNF4A interactions	KMT2C WIZ IRF2BP1 ATXN7 ZNF629 SMARCC1 SPEN MIDEAS	1.77e-05	275	83	8	int:HNF4A
Interaction	PHF23 interactions	STK11 SIN3B ATXN7L1 BRD4	2.41e-05	41	83	4	int:PHF23
Interaction	SP7 interactions	KMT2C SIN3B WIZ ATN1 IRF2BP1 SMARCC1 PROSER1 MIDEAS	3.62e-05	304	83	8	int:SP7
Interaction	SOX9 interactions	KMT2C BRD4 SMARCC1 SPEN MIDEAS	5.02e-05	97	83	5	int:SOX9
Interaction	TFCP2L1 interactions	MTA1 WIZ BRD4 SMARCC1 MIDEAS	5.54e-05	99	83	5	int:TFCP2L1
Interaction	TLX1 interactions	KMT2C WIZ ATN1 IRF2BP1 SMARCC1 MIDEAS	8.54e-05	175	83	6	int:TLX1
Interaction	TRRAP interactions	EPHX1 USP8 IRF2BP1 ATXN7 BRD4 EIF4B DCHS1 SMARCC1 SIRT6 PLEKHH2 MED26 CNTROB	9.10e-05	790	83	12	int:TRRAP
Interaction	IRF2BP2 interactions	SMG7 IRF2BP1 BRD4 SIRT6 SPEN	9.15e-05	110	83	5	int:IRF2BP2
Interaction	HNF1B interactions	KMT2C WIZ SMARCC1 PROSER1 MBD6 MIDEAS	1.34e-04	190	83	6	int:HNF1B
Interaction	CACNB1 interactions	CACNA1B ATN1 PRRT2	1.45e-04	25	83	3	int:CACNB1
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	STK11 SIN3B WIZ BRD4 SIRT6 NDUFA7 PEAK3 MED26	9.99e-05	797	83	8	chr19p13
Cytoband	9p12	ANKRD20A2P ANKRD20A3P	1.27e-03	29	83	2	9p12
GeneFamily	Ankyrin repeat domain containing	FANK1 ANKRD20A4P ANK3 ANKRD11 ANKRD20A2P ANKRD20A3P ANKRD20A1	1.19e-05	242	58	7	403
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MTA1 SMARCC1 MIDEAS	6.55e-04	53	58	3	532
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#4	TULP4 PCLO SETBP1 KDM7A PRRT2 ST18	8.65e-06	129	79	6	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K4
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	COL24A1 COBLL1 SETBP1 SFI1 MED26 CNTROB	9.05e-07	174	83	6	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	tumor_Lung-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	COL24A1 FCHSD2 COBLL1 SETBP1 ANKRD11 MED26	1.33e-06	186	83	6	3d7c1a281fb82db4471283f39937007d889a5f38
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANKRD20A4P ANKRD20A2P ANKRD20A3P RELT ST18 NLRP3	1.92e-06	198	83	6	fa5c15a656d4132950092919600e270f1fd79abf
ToppCell	mLN-(5)_Dendritic_cell-(53)_Lymphoid_DC\|mLN / shred on region, Cell_type, and subtype	ANKRD20A4P RAPH1 ANKRD20A2P ANKRD20A3P ST18 ANKRD20A1	1.92e-06	198	83	6	da84c76afe835aeee39da04b63c03549218b5d91
ToppCell	mLN-Dendritic_cell-Lymphoid_DC\|mLN / Region, Cell class and subclass	ANKRD20A4P RAPH1 ANKRD20A2P ANKRD20A3P ST18 ANKRD20A1	1.92e-06	198	83	6	3965a9f1e8a51a196e5349aaca5fa5ed1cd8ee92
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SIN3B SMG7 SMARCC1 KMT2E USP19	1.48e-05	166	83	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	COL24A1 DTX4 SETBP1 MED26 CNTROB	1.96e-05	176	83	5	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABI3BP DTX1 RAB11FIP5 ANKRD20A3P CHRNA4	2.37e-05	183	83	5	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|normal_Lung / Location, Cell class and cell subclass	COL24A1 FCHSD2 COBLL1 ANKRD11 MED26	2.37e-05	183	83	5	c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 PCLO SFI1 MYO15A ST18	2.43e-05	184	83	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ST18 ANKRD20A1	2.43e-05	184	83	5	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 PCLO SFI1 MYO15A ST18	2.43e-05	184	83	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 PCLO SFI1 MYO15A ST18	2.43e-05	184	83	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_pDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL24A1 COBLL1 SETBP1 ANKRD11 MED26	2.49e-05	185	83	5	308a98f111895071d8772bc010554471cc12fab2
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1B PCLO KSR2 DISP2 CRMP1	2.56e-05	186	83	5	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	COL24A1 ABI3BP SETBP1 LTBP1 PLEKHH2	2.62e-05	187	83	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 COBLL1 SETBP1 PLEKHH2 CRMP1	2.76e-05	189	83	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ST18 ANKRD20A1	2.90e-05	191	83	5	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ST18 ANKRD20A1	2.98e-05	192	83	5	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	COL24A1 ABI3BP SETBP1 LTBP1 PLEKHH2	3.05e-05	193	83	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CACNA1B PCLO KSR2 DISP2 PRRT2	3.13e-05	194	83	5	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2C TULP4 PCLO ANKRD11 ST18	3.21e-05	195	83	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL24A1 ABI3BP SETBP1 LTBP1 PLEKHH2	3.37e-05	197	83	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	COL24A1 NEO1 ANK3 LTBP1 PLEKHH2	3.37e-05	197	83	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B ARHGAP32 PCLO SETBP1 KSR2	3.45e-05	198	83	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B ANK3 PCLO SETBP1 KSR2	3.45e-05	198	83	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EPHX1 LRRTM3 PRRT2 PLEKHH2 FAM110B	3.53e-05	199	83	5	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EPHX1 LRRTM3 PRRT2 PLEKHH2 FAM110B	3.53e-05	199	83	5	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	PSB-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EPHX1 ARHGAP32 ANK3 CLMN CRACDL	3.53e-05	199	83	5	58dcb0eedafa8629585dc99e53147e2287f49689
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EPHX1 LRRTM3 PRRT2 PLEKHH2 FAM110B	3.53e-05	199	83	5	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CACNA1B ANK3 PCLO DISP2 CRMP1	3.53e-05	199	83	5	77b4aa00f14b86ef5db0490be98787e063979541
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 CLMN CRACDL PCLO	3.62e-05	200	83	5	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1B ANK3 PCLO SETBP1 KSR2	3.62e-05	200	83	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital\|World / Primary Cells by Cluster	NEO1 ANK3 PCLO EIF4B CRMP1	3.62e-05	200	83	5	6bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19\|World / Primary Cells by Cluster	NEO1 ANK3 PCLO EIF4B CRMP1	3.62e-05	200	83	5	c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	BRD4 ANKRD11 CILK1 KMT2E	1.29e-04	138	83	4	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL24A1 SIN3B DCHS1 CRMP1	1.97e-04	154	83	4	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FCHSD2 ANKRD20A3P RELT ST18	2.02e-04	155	83	4	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D122\|Adult / Lineage, Cell type, age group and donor	ABI3BP LTBP1 ANKRD20A3P PLEKHH2	2.17e-04	158	83	4	410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	COL24A1 NEO1 CRACDL PLEKHH2	2.44e-04	163	83	4	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANKRD20A4P ANKRD20A3P ST18 NLRP3	2.62e-04	166	83	4	479391aa6c09aa070b716128ab51b8fec0aea22d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP RAPH1 ATXN7 CRMP1	2.68e-04	167	83	4	713899690e4acd9d259645e363c26983d6ef3022
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP RAPH1 ATXN7 CRMP1	2.68e-04	167	83	4	d30b96c39da3dd02500443877a4eb3500e26802c
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1B KMT2C CLMN ST18	2.74e-04	168	83	4	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRRTM3 RELT ST18 NLRP3	2.80e-04	169	83	4	b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRRTM3 RELT ST18 NLRP3	2.80e-04	169	83	4	2322f03a115c662f808ebfc892192b7d38d48181
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	COL24A1 FCHSD2 COBLL1 SETBP1	3.13e-04	174	83	4	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL24A1 ABI3BP LTBP1 PLEKHH2	3.20e-04	175	83	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL24A1 FCHSD2 SETBP1 ANKRD11	3.20e-04	175	83	4	37c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL24A1 FCHSD2 COBLL1 SETBP1	3.20e-04	175	83	4	6d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 ABI3BP DTX1 PCLO	3.20e-04	175	83	4	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANKRD20A4P CLMN SETBP1 LTBP1	3.20e-04	175	83	4	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANKRD20A4P CLMN SETBP1 LTBP1	3.20e-04	175	83	4	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL24A1 FCHSD2 COBLL1 SETBP1	3.20e-04	175	83	4	6839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL24A1 FCHSD2 COBLL1 SETBP1	3.20e-04	175	83	4	9d6135e183179968555670abec39dff9da2c3219
ToppCell	Control-Myeloid-pDC\|Control / Disease state, Lineage and Cell class	COL24A1 FCHSD2 COBLL1 SETBP1	3.34e-04	177	83	4	3940663bb5b45b2ca9f772550380a516c53e410b
ToppCell	Control-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	COL24A1 FCHSD2 COBLL1 SETBP1	3.34e-04	177	83	4	e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCell	COPD-Myeloid-pDC\|COPD / Disease state, Lineage and Cell class	COL24A1 FCHSD2 COBLL1 SETBP1	3.34e-04	177	83	4	415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell	Control-Myeloid-pDC\|World / Disease state, Lineage and Cell class	COL24A1 FCHSD2 COBLL1 SETBP1	3.41e-04	178	83	4	20ef63d925e67ddd5955832312ca8574a6f838a4
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL24A1 DTX4 COBLL1 SETBP1	3.48e-04	179	83	4	124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL24A1 DTX4 COBLL1 SETBP1	3.48e-04	179	83	4	edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCell	COPD-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	COL24A1 FCHSD2 COBLL1 SETBP1	3.48e-04	179	83	4	29b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 RAPH1 KSR2 FAM110B	3.48e-04	179	83	4	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	IPF-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	COL24A1 FCHSD2 COBLL1 SETBP1	3.56e-04	180	83	4	0f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNRG MTA1 ABI3BP DCHS1	3.56e-04	180	83	4	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNRG MTA1 ABI3BP DCHS1	3.56e-04	180	83	4	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	moderate-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	COL24A1 FCHSD2 COBLL1 SETBP1	3.56e-04	180	83	4	1d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 COBLL1 KSR2 FAM110B	3.56e-04	180	83	4	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNRG MTA1 ABI3BP DCHS1	3.56e-04	180	83	4	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 RAPH1 COBLL1 KSR2	3.63e-04	181	83	4	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CACNA1B PCLO LRRTM3 ST18	3.71e-04	182	83	4	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	IIH-Treg-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	STK11 ATXN7L1 MYO15A LRRC8D	3.71e-04	182	83	4	5c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RAPH1 SETBP1 KDM7A FAM110B	3.71e-04	182	83	4	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FCHSD2 RELT ST18 NLRP3	3.79e-04	183	83	4	a97f052950429245c3231464271e1ba539863bba
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1	3.87e-04	184	83	4	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZIC5 ANKRD20A3P ST18 ANKRD20A1	3.87e-04	184	83	4	667846c422cfa27e949a24844a305df859cb6760
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZIC5 ANKRD20A3P ST18 ANKRD20A1	3.87e-04	184	83	4	a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 ABI3BP DISP2 PLEKHH2	3.95e-04	185	83	4	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	ABI3BP SETBP1 LTBP1 PLEKHH2	3.95e-04	185	83	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	BAL-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL24A1 FCHSD2 COBLL1 SETBP1	3.95e-04	185	83	4	f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 COBLL1 KSR2 FAM110B	3.95e-04	185	83	4	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	BAL-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL24A1 FCHSD2 COBLL1 SETBP1	3.95e-04	185	83	4	3cb816fc9541c04b4436e21d984216cfbbacff98
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 ABI3BP DISP2 PLEKHH2	3.95e-04	185	83	4	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 ABI3BP DISP2 PLEKHH2	3.95e-04	185	83	4	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ABI3BP LTBP1 PLEKHH2 FAM110B	3.95e-04	185	83	4	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	BAL-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL24A1 FCHSD2 COBLL1 SETBP1	3.95e-04	185	83	4	c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL24A1 FCHSD2 COBLL1 MIDEAS	4.03e-04	186	83	4	0096a61b1841784c913752b4f3639200446cc02c
ToppCell	Mild-Lymphoid-pDC\|Mild / Condition, Lineage, Cell class and cell subclass	COL24A1 FCHSD2 COBLL1 SETBP1	4.03e-04	186	83	4	7fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1	4.03e-04	186	83	4	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	BAL-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL24A1 FCHSD2 COBLL1 SETBP1	4.03e-04	186	83	4	b031f4e6867b6200b85f43276a34749bf5f4603f
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL24A1 FCHSD2 COBLL1 MIDEAS	4.03e-04	186	83	4	6345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1B KSR2 DISP2 CHRNA4	4.03e-04	186	83	4	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|Dendritic_cell / Lineage, cell class and subclass	COL24A1 FCHSD2 COBLL1 SETBP1	4.03e-04	186	83	4	858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCell	BAL-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL24A1 FCHSD2 COBLL1 SETBP1	4.03e-04	186	83	4	d2fbf53aac905c9896272ec5c2db28ee1a60f4be
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1	4.03e-04	186	83	4	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL24A1 FCHSD2 COBLL1 MIDEAS	4.03e-04	186	83	4	9e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCell	Mild-Lymphoid-pDC-\|Mild / Condition, Lineage, Cell class and cell subclass	COL24A1 FCHSD2 COBLL1 SETBP1	4.03e-04	186	83	4	1d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCell	BAL-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COL24A1 FCHSD2 COBLL1 SETBP1	4.03e-04	186	83	4	79aedd5aed72509a4925e9f6cb43bc0c798c86f5
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1	4.03e-04	186	83	4	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATXN7 ANKRD11 KMT2E EHD4	4.11e-04	187	83	4	663991a8afe652e92363b64bcbd68c14d0307f0e
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	SYNRG TULP4 COBLL1 PCLO ZNF629 CILK1 ADAM10	5.39e-06	191	81	7	4168_DN
Drug	(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; HL60; HT_HG-U133A	STK11 MTA1 WIZ COBLL1 SFI1 MYO15A CHRNA4	5.58e-06	192	81	7	3046_DN
Drug	Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; HL60; HT_HG-U133A	PPP1R26 STK11 ATN1 ANK3 ABI3BP COBLL1 CRMP1	6.61e-06	197	81	7	2468_UP
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; HL60; HT_HG-U133A	EPHX1 WIZ SMG7 CILK1 SFI1 SIRT6 EHD4	6.83e-06	198	81	7	2346_DN
Drug	dinophysistoxin-4	DTX1 DTX4	3.74e-05	3	81	2	CID006441267
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT_HG-U133A	STK11 SIN3B WIZ ZNF629 RAB11FIP5 LTBP1	6.39e-05	192	81	6	7427_DN
Drug	Etofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A	WIZ ATN1 COBLL1 SETBP1 SYNPO2L SFI1	6.39e-05	192	81	6	4108_UP
Drug	AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A	SMG7 IRF2BP1 CLMN COBLL1 LTBP1 SPEN	6.39e-05	192	81	6	6435_DN
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A	ATN1 SMG7 ANK3 SMARCC1 SPEN CRMP1	6.57e-05	193	81	6	4321_DN
Drug	Nilutamide [63612-50-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A	STK11 MTA1 SMG7 CLMN SFI1 SPEN	6.76e-05	194	81	6	5362_UP
Drug	Metronidazole [443-48-1]; Down 200; 23.4uM; MCF7; HT_HG-U133A	STK11 IRF2BP1 PCLO SMARCC1 PRPF19 SFI1	6.76e-05	194	81	6	4141_DN
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; PC3; HT_HG-U133A	MTA1 WIZ ATN1 IRF2BP1 BRD4 SIRT6	6.76e-05	194	81	6	4246_DN
Drug	Harpagoside [19210-12-9]; Down 200; 8uM; HL60; HT_HG-U133A	EPHX1 STK11 WIZ DTX4 PCLO USP19	7.16e-05	196	81	6	2935_DN
Drug	Lansoprazole [103577-45-3]; Up 200; 10.8uM; HL60; HT_HG-U133A	EPHX1 STK11 MTA1 SMG7 SFI1 CRMP1	7.36e-05	197	81	6	2967_UP
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A	ATN1 SMG7 IRF2BP1 COBLL1 SPEN CRMP1	7.36e-05	197	81	6	5276_UP
Drug	Lisinopril [83915-83-7]; Up 200; 9uM; HL60; HT_HG-U133A	PPP1R26 DTX4 BRD4 DCHS1 KDM7A SFI1	7.36e-05	197	81	6	2371_UP
Drug	Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; HL60; HT_HG-U133A	SMG7 IRF2BP1 BRD4 SMARCC1 SPEN CRMP1	7.36e-05	197	81	6	2353_UP
Drug	Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; HL60; HG-U133A	ARHGAP32 FCHSD2 SMG7 SIRT6 LRRC8D NLRP3	7.36e-05	197	81	6	1991_DN
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	ATN1 IRF2BP1 ATXN7 RAB11FIP5 SFI1 FAM110B	7.57e-05	198	81	6	6976_UP
Drug	Sulfasalazine [599-79-1]; Down 200; 10uM; MCF7; HT_HG-U133A	STK11 IRF2BP1 BRD4 RAB11FIP5 SIRT6 FAM110B	7.57e-05	198	81	6	2882_DN
Disease	spinocerebellar ataxia type 7 (implicated_via_orthology)	ATXN7 ATXN7L1	7.26e-06	2	80	2	DOID:0050958 (implicated_via_orthology)
Disease	Carcinoma, Pancreatic Ductal	STK11 DTX1 DTX4	3.73e-05	24	80	3	C0887833
Disease	parental longevity	FANK1 MTA1 ATXN7L1 PCLO SETBP1 KSR2 SFI1 CHRNA4	5.88e-05	494	80	8	EFO_0007796
Disease	Movement Disorders	CACNA1B ATXN7 PRRT2	6.66e-05	29	80	3	C0026650
Disease	Neurodevelopmental Disorders	KMT2C SETBP1 ANKRD11 KMT2E	1.22e-04	93	80	4	C1535926
Disease	Intellectual Disability	CACNA1B KMT2C ATN1 BRD4 SETBP1 PRRT2 KMT2E	2.14e-04	447	80	7	C3714756
Disease	Myeloid Leukemia	SETBP1 KMT2E	1.08e-03	18	80	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SETBP1 KMT2E	1.08e-03	18	80	2	C0023466
Disease	psychotic symptoms	STK11 ANK3 ST18	1.08e-03	74	80	3	EFO_0005940
Disease	diastolic blood pressure, systolic blood pressure	ANK3 ZIC5 BRD4 SETBP1 KMT2E CNTROB EHD4	2.29e-03	670	80	7	EFO_0006335, EFO_0006336

Protein segments in the cluster

Peptide	Gene	Start	Entry
LKLPTLHPKAPLSPP	ATP6V1FNB	51	A0A1B0GUX0
LHPKAPLSPPPAPKS	ATP6V1FNB	56	A0A1B0GUX0
EGPPAKHPSLKPSTE	ANKRD20A1	326	Q5TYW2
VKTRSTKAPPPHLPL	CHRNA4	546	P43681
TKAPPPHLPLSPALT	CHRNA4	551	P43681
KPLSKLHIPVIAPPP	ANKRD11	2481	Q6UB99
HPPIIAATPQPVKTK	BRD4	271	O60885
PEPPKHPESIKAPVH	BRD4	1131	O60885
VHTPSSNPKLPPPKP	ADAM10	701	O14672
EGPPAKHPSLKPSTE	ANKRD20A4P	326	Q4UJ75
SPSPPPKVVDVPSHA	ATN1	746	P54259
PPKLVLHPPPVSKSE	DTX4	351	Q9Y2E6
REPPKPKPSLSSHPT	CACNA1B	2136	Q00975
PASPEAPAHSPKAKA	DISP2	1261	A7MBM2
KRKAPSPPSKIPPHQ	COBLL1	361	Q53SF7
PIPAVIPSPSHKPSK	ATXN7L1	606	Q9ULK2
SLPQFSAPPPPLKIH	RAPH1	736	Q70E73
KPSPHPVKPLSAAPV	RAB11FIP5	521	Q9BXF6
EGPPAKHPSLKPSTE	ANKRD20A2P	326	Q5SQ80
TAVAHPGAKSVPPKP	DCHS1	3206	Q96JQ0
AAAKAQHPPLPPPST	MBD6	326	Q96DN6
LHPTKRPASNPPPIS	KDM7A	891	Q6ZMT4
PKTVDVPASLPTPPH	KMT2C	3966	Q8NEZ4
ATPKPLAPAPLAKAP	MYO15A	2516	Q9UKN7
KPPGTPPPSSRKLIH	KSR2	286	Q6VAB6
HRPEPSKPPIAPKPV	PCLO	2501	Q9Y6V0
AKSTHPPPLPAKEEP	LTBP1	766	Q14766
LVAKVPKPGADVPHP	PEAK3	201	Q6ZS72
KLPSVPTKLHCPPSP	KMT2E	1431	Q8IZD2
PSSLPPHLVPPSHRK	EHD4	521	Q9H223
PLPLPVPQPKHASQK	ARHGAP32	1456	A7KAX9
PPPKVSKASHDPLVP	MED26	161	O95402
VASKPKPHTPSLPRP	ATXN7	441	O15265
APAPSPPAPKSCLKH	CRACDL	486	Q6NV74
TRAPKPILHPPPVSK	DTX1	351	Q86Y01
PILHPPPVSKSDVKP	DTX1	356	Q86Y01
TPSPILTPALMPKHP	PLEKHH2	406	Q8IVE3
PPHSLLKAPSTPPAL	OLIG3	211	Q7RTU3
PTPAPPSMIKIVPAH	POM121B	591	A6NF01
SKPPPSTYNPHKPVP	PROSER1	186	Q86XN7
QPPPKLPVGPSHKLS	NDUFA7	36	O95182
KVAHPIRPKPPSATS	PRPF19	56	Q9UMS4
HSPPSKKSPPANGAP	PRRT2	201	Q7Z6L0
EGPPAKHPSLKPSTE	ANKRD20A3P	326	Q5VUR7
KPPQLPAGHTPKPLL	EPHX1	131	P07099
KFHKPITMTIPVPPP	ANK3	1211	Q12955
PAPPPITPKSAHRTL	MIDEAS	681	Q6PJG2
APPLPPKPKIAAIAS	FAM110B	221	Q8TC76
PPKTEVSHLHPVPPK	FAM47A	391	Q5JRC9
IQISPSPKPHASLPP	FCHSD2	641	O94868
LGPHPRSPKSVPSEK	SLC22A13	516	Q9Y226
APSAKSSPSKHQPPP	CRMP1	516	Q14194
PRIPPPVHKTKVPLA	CNTROB	751	Q8N137
SPGPPALKHPATKDL	IRF2BP1	66	Q8IU81
PVLPSPVNSKAHTPP	LRRC8D	56	Q7L1W4
DCHSPTSKPPKPDQP	EIF4B	456	P23588
PDPNPPIHKIVRKPS	NLRP3	281	Q96P20
IMPPSKPHPPVVGKV	FANK1	6	Q8TC84
KTLPHVTPKTPPPMA	SYNPO2L	696	Q9H987
KPPVPSSLASVPDPH	SFI1	1111	A8K8P3
HPTPASHPKKPGPSL	SYNRG	186	Q9UMZ2
RPKHESKPPLPPTVG	LRRTM3	386	Q86VH5
PTKAVPALGKSPPHH	SMG7	771	Q92540
SHPLKSFAVPAIPPP	NEO1	1356	Q92859
KKPAPGPHSSPPEEK	SIN3B	731	O75182
ARPAAKPTVHKEPPA	PPP1R26	81	Q5T8A7
LHISPLAKKLPPPPG	WIZ	1131	O95785
KKHPPAEAPVPIPPS	STK11	311	Q15831
LETHPRPPKPDPVKS	MTA1	541	Q13330
AVSPVSPPQHRPKTP	SPATA31C1	1166	P0DKV0
PTSPAPHRPPKRVKA	SIRT6	336	Q8N6T7
NARKRKHSPSPPPPT	SMARCC1	321	Q92922
TPPFPESKHFPNPVK	ST18	526	O60284
KPSPPLSKVSVIPHD	CLMN	711	Q96JQ2
YIKPVPPAQPPAKPH	CILK1	316	Q9UPZ9
PPAQPPAKPHTRISS	CILK1	321	Q9UPZ9
PTKIPEHSPPPKLFA	COL24A1	261	Q17RW2
PKPHLVVEKPLVSPP	TULP4	1281	Q9NRJ4
VTPKPETHLASPKPT	USP19	451	O94966
PCLHEAPPPPVDSKK	SPEN	2566	Q96T58
TLTPHHPPALPSKLP	SPEN	2981	Q96T58
PSSHKPVPIKPAPIQ	SP2	171	Q02086
VPPSGLHVPAAPTKA	SPOCD1	846	Q6ZMY3
TSHRPVSKLPPAPPN	RELT	256	Q969Z4
VSKLPPAPPNVPHIC	RELT	261	Q969Z4
NKPHSPKTPEPRRSP	PMS2CL	46	Q68D20
DPSLLTPPPGAKPHK	ZNF629	556	Q9UEG4
THTKPAPKQTPRAPP	ABI3BP	521	Q7Z7G0
PPPSEEPKTAIKHPR	SETBP1	736	Q9Y6X0
SSAPPSTPPTHKAKP	USP8	686	P40818
HMKIHCKSPPPSPGP	ZIC5	571	Q96T25