Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THSD4 PRG3 EFEMP1 MUC2 MUC4 MUC5AC	2.32e-05	188	61	6	GO:0005201
GeneOntologyBiologicalProcess	positive regulation of mitophagy	HIF1A AMBRA1 NOD2	1.28e-05	16	60	3	GO:1901526
GeneOntologyBiologicalProcess	positive regulation of autophagy of mitochondrion	HIF1A AMBRA1 NOD2	2.19e-05	19	60	3	GO:1903599
GeneOntologyBiologicalProcess	maintenance of gastrointestinal epithelium	MUC2 MUC4 NOD2	4.53e-05	24	60	3	GO:0030277
GeneOntologyCellularComponent	mucus layer	MUC2 MUC5AC	2.35e-05	3	59	2	GO:0070701
Domain	TIL_dom	LRP2 MUC2 MUC5AC	1.12e-05	14	60	3	IPR002919
Domain	VWD	MUC2 MUC4 MUC5AC	1.71e-05	16	60	3	SM00216
Domain	VWF_type-D	MUC2 MUC4 MUC5AC	1.71e-05	16	60	3	IPR001846
Domain	VWFD	MUC2 MUC4 MUC5AC	1.71e-05	16	60	3	PS51233
Domain	VWD	MUC2 MUC4 MUC5AC	1.71e-05	16	60	3	PF00094
Domain	CTCK_1	SLIT3 MUC2 MUC5AC	2.49e-05	18	60	3	PS01185
Domain	K_chnl_volt-dep_ERG	KCNH7 KCNH2	3.04e-05	3	60	2	IPR003967
Domain	CT	SLIT3 MUC2 MUC5AC	4.65e-05	22	60	3	SM00041
Domain	G8	PKHD1 PKHD1L1	6.06e-05	4	60	2	PF10162
Domain	G8_domain	PKHD1 PKHD1L1	6.06e-05	4	60	2	IPR019316
Domain	G8	PKHD1 PKHD1L1	6.06e-05	4	60	2	PS51484
Domain	G8	PKHD1 PKHD1L1	6.06e-05	4	60	2	SM01225
Domain	PAS-assoc_C	HIF1A KCNH7 KCNH2	6.08e-05	24	60	3	IPR000700
Domain	Cys_knot_C	SLIT3 MUC2 MUC5AC	6.89e-05	25	60	3	IPR006207
Domain	CTCK_2	SLIT3 MUC2 MUC5AC	6.89e-05	25	60	3	PS01225
Domain	cEGF	EFEMP1 LRP2 LRP1B	7.77e-05	26	60	3	IPR026823
Domain	PAC	HIF1A KCNH7 KCNH2	7.77e-05	26	60	3	IPR001610
Domain	cEGF	EFEMP1 LRP2 LRP1B	7.77e-05	26	60	3	PF12662
Domain	PAC	HIF1A KCNH7 KCNH2	7.77e-05	26	60	3	SM00086
Domain	PAC	HIF1A KCNH7 KCNH2	7.77e-05	26	60	3	PS50113
Domain	EGF_3	EFEMP1 SLIT3 LRP2 ADAM12 MUC4 LRP1B	1.06e-04	235	60	6	PS50026
Domain	EGF-like_dom	EFEMP1 SLIT3 LRP2 ADAM12 MUC4 LRP1B	1.45e-04	249	60	6	IPR000742
Domain	PAS	HIF1A KCNH7 KCNH2	1.46e-04	32	60	3	SM00091
Domain	PbH1	PKHD1 PKHD1L1	1.51e-04	6	60	2	SM00710
Domain	WxxW_domain	MUC2 MUC5AC	1.51e-04	6	60	2	IPR025155
Domain	Mucin2_WxxW	MUC2 MUC5AC	1.51e-04	6	60	2	PF13330
Domain	PbH1	PKHD1 PKHD1L1	1.51e-04	6	60	2	IPR006626
Domain	EGF_1	EFEMP1 SLIT3 LRP2 ADAM12 MUC4 LRP1B	1.65e-04	255	60	6	PS00022
Domain	PAS	HIF1A KCNH7 KCNH2	1.76e-04	34	60	3	IPR000014
Domain	PAS	HIF1A KCNH7 KCNH2	1.76e-04	34	60	3	PS50112
Domain	EGF-like_CS	EFEMP1 SLIT3 LRP2 ADAM12 MUC4 LRP1B	1.87e-04	261	60	6	IPR013032
Domain	EGF_2	EFEMP1 SLIT3 LRP2 ADAM12 MUC4 LRP1B	2.03e-04	265	60	6	PS01186
Domain	EGF_Ca-bd_CS	EFEMP1 SLIT3 LRP2 LRP1B	2.67e-04	97	60	4	IPR018097
Domain	Pectin_lyase_fold/virulence	PKHD1 PKHD1L1	2.81e-04	8	60	2	IPR011050
Domain	EGF_CA	EFEMP1 SLIT3 LRP2 LRP1B	2.88e-04	99	60	4	PS01187
Domain	EGF-type_Asp/Asn_hydroxyl_site	EFEMP1 SLIT3 LRP2 LRP1B	3.74e-04	106	60	4	IPR000152
Domain	PAS_9	KCNH7 KCNH2	4.49e-04	10	60	2	PF13426
Domain	EGF_CA	EFEMP1 SLIT3 LRP2 LRP1B	6.37e-04	122	60	4	SM00179
Domain	TIL	MUC2 MUC5AC	6.56e-04	12	60	2	PF01826
Domain	C8	MUC2 MUC5AC	6.56e-04	12	60	2	PF08742
Domain	EGF-like_Ca-bd_dom	EFEMP1 SLIT3 LRP2 LRP1B	6.77e-04	124	60	4	IPR001881
Domain	EGF	SLIT3 LRP2 MUC4 LRP1B	7.19e-04	126	60	4	PF00008
Domain	Unchr_dom_Cys-rich	MUC2 MUC5AC	7.74e-04	13	60	2	IPR014853
Domain	C8	MUC2 MUC5AC	7.74e-04	13	60	2	SM00832
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH7 KCNH2	9.01e-04	14	60	2	IPR003938
Domain	Ldl_recept_b	LRP2 LRP1B	9.01e-04	14	60	2	PF00058
Domain	LDLRB	LRP2 LRP1B	9.01e-04	14	60	2	PS51120
Domain	EGF	EFEMP1 SLIT3 LRP2 MUC4 LRP1B	9.40e-04	235	60	5	SM00181
Domain	EGF_extracell	LRP2 ADAM12 LRP1B	9.47e-04	60	60	3	IPR013111
Domain	EGF_2	LRP2 ADAM12 LRP1B	9.47e-04	60	60	3	PF07974
Domain	LY	LRP2 LRP1B	1.04e-03	15	60	2	SM00135
Domain	LDLR_classB_rpt	LRP2 LRP1B	1.04e-03	15	60	2	IPR000033
Domain	Disintegrin_CS	ADAM7 ADAM12	1.18e-03	16	60	2	IPR018358
Domain	ADAM_CR	ADAM7 ADAM12	1.50e-03	18	60	2	PF08516
Domain	Growth_fac_rcpt_	EFEMP1 SLIT3 LRP2 LRP1B	1.59e-03	156	60	4	IPR009030
Domain	VWC_out	MUC2 MUC5AC	1.68e-03	19	60	2	SM00215
Domain	-	ADAM7 ADAM12	1.86e-03	20	60	2	4.10.70.10
Domain	Disintegrin	ADAM7 ADAM12	2.05e-03	21	60	2	PF00200
Domain	DISIN	ADAM7 ADAM12	2.05e-03	21	60	2	SM00050
Domain	PAS_fold_3	HIF1A KCNH7	2.46e-03	23	60	2	IPR013655
Domain	PAS_3	HIF1A KCNH7	2.46e-03	23	60	2	PF08447
Domain	EGF_CA	EFEMP1 LRP2 LRP1B	2.67e-03	86	60	3	PF07645
Domain	PAS	HIF1A KCNH2	2.90e-03	25	60	2	PF00989
Domain	PAS_fold	HIF1A KCNH2	2.90e-03	25	60	2	IPR013767
Domain	HECT	UBE3B HERC1	3.38e-03	27	60	2	PF00632
Domain	HECTc	UBE3B HERC1	3.38e-03	27	60	2	SM00119
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC2 MUC4 MUC5AC	4.15e-05	21	46	3	MM15706
Pubmed	Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.	MUC2 MUC4 MUC5AC	5.13e-09	3	61	3	23464473
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC2 MUC4 MUC5AC	5.12e-08	5	61	3	11062147
Pubmed	MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.	MUC2 MUC4 MUC5AC	5.12e-08	5	61	3	16475027
Pubmed	Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease.	MUC2 MUC4 NOD2	5.12e-08	5	61	3	17058067
Pubmed	The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.	PKHD1 LRP2 PKHD1L1	5.12e-08	5	61	3	20048263
Pubmed	Arf4 is required for Mammalian development but dispensable for ciliary assembly.	PKHD1 LRP2 PKHD1L1	1.79e-07	7	61	3	24586199
Pubmed	MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer.	MUC4 MUC5AC	3.03e-06	2	61	2	18475301
Pubmed	IL-1β upregulates Muc5ac expression via NF-κB-induced HIF-1α in asthma.	HIF1A MUC5AC	3.03e-06	2	61	2	29031476
Pubmed	Mucolytic activity of bacterial and human chitinases.	MUC2 MUC5AC	3.03e-06	2	61	2	17321686
Pubmed	Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.	MUC2 MUC5AC	3.03e-06	2	61	2	20731025
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.	MUC2 MUC5AC	3.03e-06	2	61	2	23832517
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.	MUC2 MUC5AC	3.03e-06	2	61	2	23832516
Pubmed	Alteration of ocular surface mucins in MUC5AC-DTA transgenic mice.	MUC4 MUC5AC	3.03e-06	2	61	2	19158956
Pubmed	Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.	MUC2 MUC5AC	3.03e-06	2	61	2	17203232
Pubmed	Hypoxia induces mucin expression and secretion in human bronchial epithelial cells.	HIF1A MUC5AC	3.03e-06	2	61	2	23084780
Pubmed	Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.	MUC2 MUC5AC	3.03e-06	2	61	2	12527922
Pubmed	Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons.	KCNH7 KCNH2	3.03e-06	2	61	2	19359372
Pubmed	Hypoxia-mediated mechanism of MUC5AC production in human nasal epithelia and its implication in rhinosinusitis.	HIF1A MUC5AC	3.03e-06	2	61	2	24840724
Pubmed	The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair.	KIF18B TP53BP1	3.03e-06	2	61	2	34192545
Pubmed	Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1α via epidermal growth factor receptor-mediated signaling pathways.	HIF1A MUC5AC	3.03e-06	2	61	2	21544845
Pubmed	In vivo glycosylation of mucin tandem repeats.	MUC2 MUC5AC	3.03e-06	2	61	2	11445551
Pubmed	Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.	MUC2 MUC5AC	3.03e-06	2	61	2	14594655
Pubmed	Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.	MUC2 MUC5AC	3.03e-06	2	61	2	12820724
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC2 MUC4 MUC5AC	4.11e-06	18	61	3	18834073
Pubmed	Detection of genes regulated by Lmx1b during limb dorsalization.	EFEMP1 LMX1B INSYN2B	8.87e-06	23	61	3	22417325
Pubmed	Secretory carcinoma of breast: pattern of MUC 2/MUC 4/MUC 6 expression.	MUC2 MUC4	9.07e-06	3	61	2	23305535
Pubmed	Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice.	MUC2 MUC4	9.07e-06	3	61	2	24714692
Pubmed	Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization.	KCNH7 KCNH2	9.07e-06	3	61	2	15961404
Pubmed	Differences in the expression of mucins in various forms of cystitis glandularis.	MUC2 MUC5AC	9.07e-06	3	61	2	17659847
Pubmed	Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.	MUC2 MUC5AC	9.07e-06	3	61	2	18825309
Pubmed	Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.	MUC2 MUC5AC	9.07e-06	3	61	2	18300795
Pubmed	Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.	MUC2 MUC5AC	9.07e-06	3	61	2	17333267
Pubmed	HERG K(+) currents in human prolactin-secreting adenoma cells.	KCNH7 KCNH2	9.07e-06	3	61	2	12634931
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC2 MUC5AC	9.07e-06	3	61	2	19718741
Pubmed	Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.	KCNH7 KCNH2	9.07e-06	3	61	2	14643686
Pubmed	ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models.	HIF1A ITGA6	9.07e-06	3	61	2	27001172
Pubmed	Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.	MUC2 MUC4	9.07e-06	3	61	2	20065027
Pubmed	Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.	KCNH7 KCNH2	9.07e-06	3	61	2	35818223
Pubmed	Gene expression profiling of colorectal mucinous adenocarcinomas.	MUC2 MUC5AC	9.07e-06	3	61	2	20485009
Pubmed	Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont.	MUC2 NOD2	9.07e-06	3	61	2	37967555
Pubmed	Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.	MUC2 MUC5AC	9.07e-06	3	61	2	24920497
Pubmed	The role of the XBP-1/AGR2 signaling pathway in the regulation of airway Mucin5ac hypersecretion under hypoxia.	HIF1A MUC5AC	1.81e-05	4	61	2	31128106
Pubmed	Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M.	HIF1A OSMR	1.81e-05	4	61	2	31249305
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC2 MUC5AC	1.81e-05	4	61	2	25638393
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC2 MUC5AC	1.81e-05	4	61	2	22269464
Pubmed	Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.	MUC2 MUC5AC	1.81e-05	4	61	2	22691042
Pubmed	Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.	GIT2 NOD2	1.81e-05	4	61	2	37156999
Pubmed	Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells.	MUC2 MUC5AC	1.81e-05	4	61	2	12391274
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC2 MUC5AC	1.81e-05	4	61	2	23807779
Pubmed	Mucin expression pattern in pancreatic diseases: findings from EUS-guided fine-needle aspiration biopsies.	MUC2 MUC4	1.81e-05	4	61	2	21647207
Pubmed	FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.	FST ADAM12	1.81e-05	4	61	2	15574124
Pubmed	Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.	MUC2 MUC5AC	1.81e-05	4	61	2	33154304
Pubmed	Gastric mucin expression in first-degree relatives of gastric cancer patients.	MUC2 MUC5AC	1.81e-05	4	61	2	24901817
Pubmed	The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding.	BMPR1A FST	1.81e-05	4	61	2	16198295
Pubmed	Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).	MUC2 MUC5AC	1.81e-05	4	61	2	36367122
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC2 MUC5AC	1.81e-05	4	61	2	17471237
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC2 MUC5AC	1.81e-05	4	61	2	14984930
Pubmed	HIF-1α, NOTCH1, ADAM12, and HB-EGF are overexpressed in mucoepidermoid carcinoma.	HIF1A ADAM12	1.81e-05	4	61	2	30415904
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC2 MUC5AC	1.81e-05	4	61	2	29869461
Pubmed	[Expression and clinical significance of Mucin and E-cadherin in colorectal tumors].	MUC2 MUC5AC	1.81e-05	4	61	2	17991319
Pubmed	Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?	MUC2 MUC5AC	1.81e-05	4	61	2	20929551
Pubmed	MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.	MUC2 MUC5AC	1.81e-05	4	61	2	27298226
Pubmed	PGE(2) induces MUC2 and MUC5AC expression in human intrahepatic biliary epithelial cells via EP4/p38MAPK activation.	MUC2 MUC5AC	1.81e-05	4	61	2	23619266
Pubmed	Butyrate enemas upregulate Muc genes expression but decrease adherent mucus thickness in mice colon.	MUC2 MUC4	1.81e-05	4	61	2	18198997
Pubmed	Mucin expression profile in Barrett's, dysplasia, adenocarcinoma sequence in the esophagus.	MUC2 MUC5AC	1.81e-05	4	61	2	17401217
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC2 MUC5AC	1.81e-05	4	61	2	12676567
Pubmed	Expression profile of mucins (MUC1, MUC2, MUC5AC, and MUC6) in ovarian mucinous tumours: changes in expression from benign to malignant tumours.	MUC2 MUC5AC	1.81e-05	4	61	2	25298197
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LMX1B MYO9B KCNH2 UBE3B KAT6A AMBRA1 BTAF1 HERC1 ARHGEF11 NOD2	2.08e-05	1105	61	10	35748872
Pubmed	Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1.	ANLN LRP2	3.02e-05	5	61	2	17283184
Pubmed	Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14.	MUC2 MUC5AC	3.02e-05	5	61	2	12507512
Pubmed	Association between genetic variants in myosin IXB and Crohn's disease.	MYO9B NOD2	3.02e-05	5	61	2	19235913
Pubmed	Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.	MUC2 MUC5AC	3.02e-05	5	61	2	12135769
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC2 MUC5AC	3.02e-05	5	61	2	16188033
Pubmed	Multifaceted transcriptional regulation of the murine intestinal mucus layer by endogenous microbiota.	MUC2 MUC4	3.02e-05	5	61	2	18035521
Pubmed	Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons.	BMPR1A FST	3.02e-05	5	61	2	11580864
Pubmed	pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins.	MUC2 MUC5AC	3.02e-05	5	61	2	10611155
Pubmed	Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?	MUC2 MUC5AC	3.02e-05	5	61	2	22261707
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC2 MUC5AC	4.52e-05	6	61	2	19110483
Pubmed	Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum.	MUC2 MUC5AC	4.52e-05	6	61	2	16142311
Pubmed	Biosynthesis of gastrokine-2 in the human gastric mucosa: restricted spatial expression along the antral gland axis and differential interaction with TFF1, TFF2 and mucins.	MUC2 MUC5AC	4.52e-05	6	61	2	17982272
Pubmed	Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease.	BSN NOD2	4.52e-05	6	61	2	20024904
Pubmed	The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression.	HIF1A TP53BP1	4.52e-05	6	61	2	17024177
Pubmed	FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development.	BMPR1A FST	4.52e-05	6	61	2	21084449
Pubmed	Increased GIP signaling induces adipose inflammation via a HIF-1α-dependent pathway and impairs insulin sensitivity in mice.	GIPR HIF1A	4.52e-05	6	61	2	25537494
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	HIF1A MYO9B BTAF1 XPOT	6.04e-05	120	61	4	27320910
Pubmed	Glucose metabolism induced by Bmp signaling is essential for murine skeletal development.	BMPR1A HIF1A	8.42e-05	8	61	2	30446646
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RLF ANLN KAT6A BTAF1 KIF18B PRDM15 ZMYM4	9.29e-05	608	61	7	36089195
Pubmed	DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins.	BMPR1A FST	1.08e-04	9	61	2	20860622
Pubmed	Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.	KCNH7 KCNH2	1.35e-04	10	61	2	26503718
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BMPR1A SLC16A1 KAT6A SCAPER LRP2 AMBRA1 OSMR KIF18B ZNF574	1.35e-04	1116	61	9	31753913
Pubmed	Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.	GIPR LMX1B LRP1B	1.48e-04	58	61	3	20935630
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	THSD4 PRG3 EFEMP1 MUC2	1.55e-04	153	61	4	25037231
Pubmed	Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.	HIF1A LRP2	1.65e-04	11	61	2	19416849
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP2 LRP1B	1.65e-04	11	61	2	24639464
Pubmed	Convergence of bone morphogenetic protein and laminin-1 signaling pathways promotes proliferation and colony formation by fetal mouse pancreatic cells.	BMPR1A ITGA6	1.97e-04	12	61	2	15913604
Pubmed	Association of genetic profiles to Crohn's disease by linear combinations of single nucleotide polymorphisms.	MYO9B NOD2	1.97e-04	12	61	2	18804983
Pubmed	BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb.	BMPR1A LMX1B	1.97e-04	12	61	2	11714671
Pubmed	Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.	BSN TP53BP1	1.97e-04	12	61	2	28700933
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	HIF1A KAT6A LRP2 ARHGEF11 NOD2	2.25e-04	313	61	5	20800603
Pubmed	Conditional stabilization of beta-catenin expands the pool of lung stem cells.	MUC2 MUC5AC	2.33e-04	13	61	2	18356571
Cytoband	2q21.2	LYPD1 LRP1B	1.56e-04	14	61	2	2q21.2
GeneFamily	CD molecules\|Mucins	MUC2 MUC4 MUC5AC	1.73e-05	21	44	3	648
GeneFamily	Low density lipoprotein receptors	LRP2 LRP1B	4.44e-04	13	44	2	634
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZBTB49 ZNF492 ZNF781 SCAPER PRDM15 ZNF574	1.61e-03	718	44	7	28
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM7 ADAM12	1.95e-03	27	44	2	47
GeneFamily	Potassium voltage-gated channels	KCNH7 KCNH2	4.26e-03	40	44	2	274
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	RLF BMPR1A HIF1A MYO9B KAT6A USP12 ITGA6 BTAF1 OSMR CAMSAP2 ZMYM4 TP53BP1	5.45e-07	856	61	12	M4500
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	RLF EXOC5 HIF1A ITGA6 INSYN2B HERC1 FST	4.61e-06	233	61	7	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_1000	SCAPER ITGA6 PHF7 INSYN2B HERC1 FST	8.69e-06	168	61	6	gudmap_developingGonad_P2_ovary_1000_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000	SCAPER ITGA6 PHF7 INSYN2B HERC1 FST	1.25e-05	179	61	6	gudmap_developingGonad_e14.5_ ovary_1000_k5
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51AP2 GIPR HERC1 BSN MUC4 XPOT	1.43e-07	174	61	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DLGAP1 LYPD1 SLIT3 PKHD1 LRP2	3.44e-06	168	61	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 SLC16A1 SLITRK4 LRP2 PKHD1L1	4.56e-06	178	61	5	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 EFEMP1 SLITRK4 LRP2 PKHD1L1	4.56e-06	178	61	5	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 EFEMP1 SLITRK4 LRP2 PKHD1L1	4.56e-06	178	61	5	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51AP2 GIPR HERC1 BSN MUC4	4.56e-06	178	61	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THSD4 EFEMP1 SLITRK4 LRP1B PKHD1L1	5.35e-06	184	61	5	607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	EFEMP1 SLC16A1 SLIT3 OSMR PKHD1L1	5.50e-06	185	61	5	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 LRP2 FST PKHD1L1	5.79e-06	187	61	5	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 LRP2 FST PKHD1L1	5.79e-06	187	61	5	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 LRP2 FST PKHD1L1	5.79e-06	187	61	5	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	COPD-Epithelial-Mesothelial\|COPD / Disease state, Lineage and Cell class	EFEMP1 SLC16A1 SLIT3 OSMR PKHD1L1	6.10e-06	189	61	5	79bb2593ad5d17f94b17972884241f03a0f43770
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFEMP1 SLC16A1 SLIT3 LRP2 PKHD1L1	6.42e-06	191	61	5	5343a527de6b0f852f45020a91f5b4869e78f13a
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFEMP1 SLC16A1 SLIT3 LRP2 PKHD1L1	6.42e-06	191	61	5	a25a5f9a380031fdaf57677a079f97a90f0550c0
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EFEMP1 SLIT3 OSMR FST LRP1B	7.46e-06	197	61	5	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EFEMP1 SLIT3 OSMR FST LRP1B	7.46e-06	197	61	5	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EFEMP1 SLIT3 OSMR FST LRP1B	7.46e-06	197	61	5	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Mesothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	EFEMP1 SLC16A1 SLIT3 FST PKHD1L1	8.02e-06	200	61	5	c800f20adedf4ca736c740510889e92d8bf0ba44
ToppCell	Parenchyma_COVID-19-Stromal-TX-Mesothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	EFEMP1 SLC16A1 SLIT3 FST PKHD1L1	8.02e-06	200	61	5	bf50e30d5cafb71c567e89580f62084d2f894170
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Mesothelial-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	EFEMP1 SLC16A1 SLIT3 FST PKHD1L1	8.02e-06	200	61	5	5e5ad07679d5dd2ca80249bce9aaf4a95d42187b
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	KCNH2 LRP2 BSN MUC2	5.21e-05	149	61	4	649eb3441fa859591ea85f1ed5fcf08af272a32b
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	THSD4 EFEMP1 LMX1B PKHD1	5.77e-05	153	61	4	151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSYN2B FST ADAM12 XPOT	6.54e-05	158	61	4	12661763d1c309106801cb710c04cd2b62d16cba
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSYN2B FST ADAM12 XPOT	6.54e-05	158	61	4	e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSYN2B FST ADAM12 XPOT	6.54e-05	158	61	4	0792c39e6fc0745095af7812de2d50949540d60f
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GIPR LYPD1 KCNH7 BSN	6.70e-05	159	61	4	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 LRP1B PKHD1L1	6.86e-05	160	61	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 LRP1B PKHD1L1	6.86e-05	160	61	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANLN SLIT3 KIF18B ADAM12	7.03e-05	161	61	4	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANLN SLIT3 KIF18B ADAM12	7.03e-05	161	61	4	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM7 PKHD1 LRP1B PKHD1L1	7.20e-05	162	61	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HIF1A ADAM12 MUC2 MUC5AC	7.55e-05	164	61	4	3c15e9b8403b03d67f6ecd7861dc19f1261e3244
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RAD51AP2 SLIT3 FST MUC5AC	7.73e-05	165	61	4	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	Control-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	EFEMP1 SLIT3 FST PKHD1L1	7.92e-05	166	61	4	32ebaefa6c074b28193fff764ee7c2c0e9357e20
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 SLC16A1 SLITRK4 PKHD1L1	7.92e-05	166	61	4	545f6c91102568791443717e522f89cb3bd1a070
ToppCell	moderate-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	BMPR1A KCNH2 ADAM12 LRP1B	7.92e-05	166	61	4	c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell	Control-Epithelial-Mesothelial\|Control / Disease state, Lineage and Cell class	EFEMP1 SLIT3 FST PKHD1L1	7.92e-05	166	61	4	1ed3788257e14f097862b999f020bfe2a57de52b
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFEMP1 SLC16A1 LRP2 PKHD1L1	8.10e-05	167	61	4	c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 EFEMP1 SLC16A1 PKHD1L1	8.10e-05	167	61	4	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 EFEMP1 SLC16A1 PKHD1L1	8.10e-05	167	61	4	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFEMP1 SLC16A1 LRP2 PKHD1L1	8.10e-05	167	61	4	351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 LRP1B PKHD1L1	8.48e-05	169	61	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 SLIT3 SLITRK4 FST	8.88e-05	171	61	4	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HIF1A MYO9B SLITRK4 NOD2	8.88e-05	171	61	4	5e93c76ee60f9d0590ebb140812653a5e1369417
ToppCell	11.5-Airway-Epithelial-Basal_cell\|Airway / Age, Tissue, Lineage and Cell class	EFEMP1 MUC2 MUC4 MUC5AC	9.08e-05	172	61	4	9d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 SLC16A1 SLITRK4 PKHD1L1	9.08e-05	172	61	4	9a256db817c1af1802203cc88a55d608fb328c63
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	DLGAP1 LYPD1 SLIT3 LRP2	9.08e-05	172	61	4	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFEMP1 SLC16A1 SLITRK4 PKHD1L1	9.29e-05	173	61	4	ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	THSD4 ZNF492 SLITRK4 LRP1B	9.29e-05	173	61	4	b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFEMP1 SLC16A1 SLITRK4 PKHD1L1	9.29e-05	173	61	4	3725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 EFEMP1 SLC16A1 PKHD1L1	9.29e-05	173	61	4	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RAD51AP2 SLIT3 FST MUC5AC	9.29e-05	173	61	4	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 EFEMP1 SLC16A1 PKHD1L1	9.50e-05	174	61	4	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	PKHD1 LRP2 CRPPA LRP1B	9.92e-05	176	61	4	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LYPD1 ANLN KIF18B FST	1.01e-04	177	61	4	3e149bff1f1b393a7abe98984e37981c8296f95d
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EFEMP1 SLC16A1 FST PKHD1L1	1.01e-04	177	61	4	0912a291cff32a4ff8a2d7680ed1a1cd867fb90f
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LYPD1 LRP2 ITGA6 ADAM12	1.01e-04	177	61	4	59726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 EFEMP1 LRP2 PKHD1L1	1.04e-04	178	61	4	a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DLGAP1 SLIT3 PKHD1 LRP2	1.04e-04	178	61	4	544379f5a6145429762258d426b876bb36c112f5
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFEMP1 SLIT3 LRP2 PKHD1L1	1.06e-04	179	61	4	056df2aaff750e0e283e7da78fcc3c90c366aac0
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLITRK4 LRP2 MUC4 PKHD1L1	1.06e-04	179	61	4	4135f9e8cd8494cbc189e5210dded84659643fb8
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFEMP1 SLIT3 LRP2 PKHD1L1	1.06e-04	179	61	4	f5f3945ef3b9efc5921a71fd51deeb2c80f0ce11
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	EFEMP1 SLC16A1 SLIT3 PKHD1L1	1.08e-04	180	61	4	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 SLC16A1 SLITRK4 PKHD1L1	1.08e-04	180	61	4	2ccc77d769d3ffd77ab3af45e4f192785b6db79c
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFEMP1 SLC16A1 LRP2 PKHD1L1	1.11e-04	181	61	4	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THSD4 EFEMP1 OSMR MUC4	1.11e-04	181	61	4	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SLC16A1 KCNH2 FST ADAM12	1.11e-04	181	61	4	ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFEMP1 SLC16A1 LRP2 PKHD1L1	1.11e-04	181	61	4	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFEMP1 LRP2 PKHD1L1 MUC5AC	1.15e-04	183	61	4	9d5a363fbe6f0a1668c9d584df65ee1c283349c7
ToppCell	IPF-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	EFEMP1 SLC16A1 SLIT3 PKHD1L1	1.15e-04	183	61	4	7df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFEMP1 LRP2 PKHD1L1 MUC5AC	1.15e-04	183	61	4	c5caac6ed6c8d67f5c336281d9fd903976509445
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 EFEMP1 SLITRK4 PKHD1L1	1.15e-04	183	61	4	ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 LRP1B PKHD1L1	1.18e-04	184	61	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 OSMR ADAM12 LRP1B	1.18e-04	184	61	4	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 LRP1B PKHD1L1	1.18e-04	184	61	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 LRP1B PKHD1L1	1.18e-04	184	61	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Epithelial-Mesothelial\|Epithelial / Disease state, Lineage and Cell class	SLC16A1 SLIT3 FST PKHD1L1	1.20e-04	185	61	4	0af540323c0113203ba6c1a4cb32d2fb9cf79d39
ToppCell	droplet-Tongue-nan-24m-Epithelial-basal_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 ITGA6 OSMR FST	1.25e-04	187	61	4	13056622d9921ee0b03325701d94df82ffbaa5d4
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THSD4 SLIT3 OSMR ADAM12	1.25e-04	187	61	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RLF BTAF1 HERC1 TP53BP1	1.28e-04	188	61	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	COPD-Epithelial-Mesothelial\|Epithelial / Disease state, Lineage and Cell class	HIF1A SLC16A1 SLIT3 PKHD1L1	1.28e-04	188	61	4	159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCell	droplet-Tongue-nan-24m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 ANLN OSMR NOD2	1.31e-04	189	61	4	258ef4a52f90236dbed92f325ca033c8fa6156a5
ToppCell	Severe_COVID-19-Epithelial-undefined_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	OSMR MUC4 PKHD1L1 MUC5AC	1.31e-04	189	61	4	8cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 OSMR FST	1.33e-04	190	61	4	990ac07f4b0a22041daac7502f74fafd6d258cba
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 DLGAP1 SLIT3 ADAM12	1.33e-04	190	61	4	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 DLGAP1 SLIT3 ADAM12	1.33e-04	190	61	4	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 OSMR FST	1.33e-04	190	61	4	fc9bbe5e6e0ec3cfa47bf479d8b09a0fc53169cc
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 OSMR FST	1.33e-04	190	61	4	39ecdf8815e235771132684dfc1aff1917e20965
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 DLGAP1 SLIT3 ADAM12	1.36e-04	191	61	4	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 DLGAP1 SLIT3 CRPPA	1.36e-04	191	61	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 DLGAP1 SLIT3 ADAM12	1.39e-04	192	61	4	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PKHD1 LRP2 ITGA6 KIF18B	1.39e-04	192	61	4	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 DLGAP1 SLIT3 ADAM12	1.39e-04	192	61	4	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EFEMP1 SLIT3 OSMR FST	1.39e-04	192	61	4	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EFEMP1 SLIT3 OSMR FST	1.39e-04	192	61	4	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LMX1B PKHD1 LRP2 MUC5AC	1.39e-04	192	61	4	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EFEMP1 SLIT3 OSMR FST	1.39e-04	192	61	4	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 FST ADAM12	1.41e-04	193	61	4	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 SLIT3 FST ADAM12	1.41e-04	193	61	4	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GIPR SCAPER BTAF1 HERC1	1.41e-04	193	61	4	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
Drug	Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; MCF7; HT_HG-U133A	GIPR KCNH2 KAT6A PHF7 ADAM12 MUC4 MUC5AC	9.27e-07	196	61	7	2221_UP
Drug	Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	GIPR ADAM7 LRP2 PHF7 FST MUC4	1.37e-05	195	61	6	6039_UP
Drug	Strophanthidin [66-28-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A	EXOC5 LYPD1 MYO9B KCNH2 UBE3B ITGA6	1.41e-05	196	61	6	7182_UP
Drug	Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; MCF7; HT_HG-U133A	EXOC5 ITGA6 AMBRA1 GIT2 ARHGEF11 ZNF574	1.45e-05	197	61	6	2635_DN
Drug	Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A	KCNH2 KAT6A SCAPER LRP2 FST ADAM12	1.54e-05	199	61	6	3839_UP
Drug	Ovalbumin	HIF1A LRP2 MUC2 MUC5AC	6.98e-05	82	61	4	ctd:D010047
Drug	Doxazosin	KCNH7 KCNH2	1.05e-04	6	61	2	DB00590
Drug	Prazosin	KCNH7 KCNH2	1.05e-04	6	61	2	DB00457
Drug	Terazosin	KCNH7 KCNH2	1.05e-04	6	61	2	DB01162
Drug	Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	EXOC5 LYPD1 SCAPER GIT2 OSMR	1.60e-04	191	61	5	7195_UP
Drug	Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A	RLF LYPD1 SLC16A1 GIT2 ARHGEF11	1.64e-04	192	61	5	6207_DN
Drug	Glycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A	LMX1B GIT2 OSMR FST MUC5AC	1.72e-04	194	61	5	4709_UP
Drug	Riluzole hydrochloride; Down 200; 14.8uM; MCF7; HT_HG-U133A	LYPD1 MYO9B UBE3B GIT2 OSMR	1.72e-04	194	61	5	2295_DN
Drug	Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A	THSD4 MYO9B KAT6A LRP2 FST	1.72e-04	194	61	5	2789_UP
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A	EXOC5 EFEMP1 UBE3B OSMR MUC2	1.72e-04	194	61	5	7494_UP
Drug	11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	EXOC5 KAT6A ITGA6 GIT2 OSMR	1.72e-04	194	61	5	7538_DN
Drug	Butylparaben [94-26-8]; Up 200; 20.6uM; PC3; HT_HG-U133A	ADAM7 PHF7 MUC2 MUC4 NOD2	1.77e-04	195	61	5	4647_UP
Drug	Butylparaben [94-26-8]; Down 200; 20.6uM; MCF7; HT_HG-U133A	MYO9B KCNH2 UBE3B ARHGEF11 ZMYM4	1.77e-04	195	61	5	5245_DN
Drug	Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	SLC16A1 MYO9B KCNH2 AMBRA1 GIT2	1.77e-04	195	61	5	2649_DN
Drug	Oxolinic acid [14698-29-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	KAT6A SCAPER ITGA6 AMBRA1 GIT2	1.81e-04	196	61	5	5519_DN
Drug	Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A	KAT6A GIT2 OSMR ARHGEF11 ZNF574	1.81e-04	196	61	5	4347_DN
Drug	Estriol [50-27-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A	DLGAP1 PHF7 OSMR ARHGEF11 MUC5AC	1.81e-04	196	61	5	3563_UP
Drug	Cyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; PC3; HT_HG-U133A	SCAPER LRP2 AMBRA1 PHF7 GIT2	1.81e-04	196	61	5	5734_DN
Drug	Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	LYPD1 KCNH2 UBE3B OSMR ZMYM4	1.81e-04	196	61	5	7357_DN
Drug	Dydrogesterone [152-62-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A	LYPD1 MYO9B KCNH2 SCAPER AMBRA1	1.81e-04	196	61	5	2811_DN
Drug	Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A	GIPR PHF7 MUC2 MUC4 NOD2	1.81e-04	196	61	5	4407_UP
Drug	Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A	THSD4 MYO9B ADAM7 FST ADAM12	1.85e-04	197	61	5	3617_UP
Drug	Fipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; MCF7; HT_HG-U133A	MYO9B KCNH2 ITGA6 GIT2 ARHGEF11	1.85e-04	197	61	5	3176_DN
Drug	Lovastatin [75330-75-5]; Down 200; 9.8uM; HL60; HT_HG-U133A	LRP2 PHF7 ARHGEF11 CAMSAP2 NOD2	1.85e-04	197	61	5	2494_DN
Drug	6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A	LMX1B KAT6A GIT2 ADAM12 NOD2	1.85e-04	197	61	5	6813_UP
Drug	Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A	EFEMP1 MYO9B UBE3B SCAPER ARHGEF11	1.85e-04	197	61	5	6204_UP
Drug	Pralidoxime chloride [51-15-0]; Down 200; 23.2uM; MCF7; HT_HG-U133A	EXOC5 ITGA6 GIT2 ARHGEF11 ZNF574	1.85e-04	197	61	5	6443_DN
Drug	Meropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A	LYPD1 MYO9B SCAPER ITGA6 OSMR	1.85e-04	197	61	5	7180_UP
Drug	Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT_HG-U133A	KAT6A LRP2 PHF7 MUC2 MUC5AC	1.85e-04	197	61	5	4658_UP
Drug	Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A	PRG3 LMX1B KCNH2 SCAPER MUC4	1.85e-04	197	61	5	6091_UP
Drug	Cholecalciferol [67-97-0]; Up 200; 10.4uM; HL60; HT_HG-U133A	LRP2 ADAM12 CAMSAP2 MUC4 NOD2	1.90e-04	198	61	5	2436_UP
Drug	Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A	THSD4 LMX1B SCAPER GIT2 ARHGEF11	1.90e-04	198	61	5	4717_UP
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A	EXOC5 ITGA6 GIT2 OSMR ZMYM4	1.90e-04	198	61	5	6241_DN
Drug	Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; PC3; HT_HG-U133A	MYO9B KAT6A AMBRA1 GIT2 ARHGEF11	1.90e-04	198	61	5	7257_UP
Drug	Metyrapone [54-36-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A	SCAPER LRP2 OSMR MUC4 NOD2	1.90e-04	198	61	5	6447_UP
Drug	Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MYO9B LRP2 GIT2 OSMR ZNF574	1.94e-04	199	61	5	3344_DN
Drug	Mafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A	GIPR SCAPER LRP2 PHF7 MUC5AC	1.94e-04	199	61	5	5079_UP
Drug	rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	LYPD1 MYO9B SCAPER ITGA6 ARHGEF11	1.94e-04	199	61	5	6950_DN
Drug	estradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A	EFEMP1 SLC16A1 ITGA6 GIT2 ZNF574	1.94e-04	199	61	5	6968_DN
Drug	Chenodiol [474-25-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A	THSD4 LMX1B MYO9B PHF7 ADAM12	1.94e-04	199	61	5	6012_UP
Drug	Methantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A	SLC16A1 ADAM7 SCAPER ADAM12 MUC5AC	1.94e-04	199	61	5	3560_UP
Drug	4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid	MUC2 MUC5AC	1.96e-04	8	61	2	ctd:C064545
Drug	Miconazole	KCNH7 KCNH2	1.96e-04	8	61	2	DB01110
Drug	chlorpropamide; Down 200; 100uM; MCF7; HG-U133A	SLIT3 USP12 FST ADAM12 ZMYM4	1.99e-04	200	61	5	141_DN
Drug	Flucytosine [2022-85-7]; Up 200; 31uM; MCF7; HT_HG-U133A	LMX1B SCAPER LRP2 FST NOD2	1.99e-04	200	61	5	6450_UP
Drug	Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A	THSD4 GIPR EXOC5 KCNH2 MUC5AC	1.99e-04	200	61	5	4787_UP
Drug	linopirdine	KCNH7 KCNH2 BSN	2.09e-04	43	61	3	CID000003932
Disease	mucinous adenocarcinoma (is_marker_for)	MUC2 MUC4 MUC5AC	7.57e-08	5	59	3	DOID:3030 (is_marker_for)
Disease	cystitis (is_marker_for)	MUC2 MUC5AC	3.93e-06	2	59	2	DOID:1679 (is_marker_for)
Disease	sputum mucin-5B amount	MUC2 MUC5AC	1.18e-05	3	59	2	OBA_2050332
Disease	intestinal disease (is_implicated_in)	BMPR1A NOD2	1.18e-05	3	59	2	DOID:5295 (is_implicated_in)
Disease	epilepsy (implicated_via_orthology)	KCNH7 KCNH2 ITGA6 BSN LRP1B	1.90e-05	163	59	5	DOID:1826 (implicated_via_orthology)
Disease	mucositis (biomarker_via_orthology)	MUC2 MUC4	3.92e-05	5	59	2	DOID:0080178 (biomarker_via_orthology)
Disease	disease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	THSD4 ADAM12 LRP1B	3.97e-05	33	59	3	EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090
Disease	Schizophrenia	DLGAP1 LMX1B MYO9B KCNH2 SLIT3 LRP2 AMBRA1 ARHGEF11 ADAM12	6.07e-05	883	59	9	C0036341
Disease	fat body mass	THSD4 DLGAP1 KCNH7 LMX1B CRPPA	7.45e-05	217	59	5	EFO_0005409
Disease	Stage IV Skin Melanoma	ADAM7 ADAM12	8.20e-05	7	59	2	C1321872
Disease	biliary tract benign neoplasm (is_marker_for)	MUC4 MUC5AC	8.20e-05	7	59	2	DOID:0050625 (is_marker_for)
Disease	common bile duct neoplasm (is_marker_for)	MUC4 MUC5AC	1.09e-04	8	59	2	DOID:4608 (is_marker_for)
Disease	health-related quality of life measurement	EXOC5 LMX1B	1.40e-04	9	59	2	EFO_0011014
Disease	bringing up phlegm, sputum or mucus on most days, self-reported	MUC2 MUC5AC	1.40e-04	9	59	2	EFO_0009824
Disease	Focal segmental glomerulosclerosis	LMX1B ANLN	1.75e-04	10	59	2	cv:C0017668
Disease	Inherited focal segmental glomerulosclerosis	LMX1B ANLN	1.75e-04	10	59	2	cv:CN327126
Disease	allergic conjunctivitis (is_marker_for)	MUC2 MUC4	1.75e-04	10	59	2	DOID:11204 (is_marker_for)
Disease	long QT syndrome (implicated_via_orthology)	KCNH7 KCNH2	1.75e-04	10	59	2	DOID:2843 (implicated_via_orthology)
Disease	Hereditary Nephrotic Syndromes, Autosomal Dominant	LMX1B ANLN	2.14e-04	11	59	2	cv:CN043612
Disease	endometrial neoplasm	ADAM12 ZMYM4	2.14e-04	11	59	2	EFO_0004230
Disease	follistatin measurement	FST TP53BP1	2.14e-04	11	59	2	EFO_0010614
Disease	Abruptio Placentae	INSYN2B ADAM12	2.56e-04	12	59	2	EFO_1001754
Disease	glaucoma	EFEMP1 LMX1B PKHD1 LRP1B	2.60e-04	154	59	4	MONDO_0005041
Disease	Non-Small Cell Lung Carcinoma	GIPR HIF1A OSMR TP53BP1	2.73e-04	156	59	4	C0007131
Disease	cholangiocarcinoma (is_marker_for)	MUC2 MUC4 MUC5AC	2.90e-04	64	59	3	DOID:4947 (is_marker_for)
Disease	Familial idiopathic steroid-resistant nephrotic syndrome	LMX1B ANLN	3.02e-04	13	59	2	cv:C4273714
Disease	keratoconus	PKHD1 FST LRP1B	3.18e-04	66	59	3	MONDO_0015486
Disease	lysophosphatidylcholine 15:0 measurement	PKHD1 LRP1B	3.52e-04	14	59	2	EFO_0020941
Disease	susceptibility to childhood ear infection measurement	EFEMP1 CRPPA BSN ADAM12	3.87e-04	171	59	4	EFO_0007904
Disease	unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	THSD4 ADAM12 LRP1B	4.81e-04	76	59	3	EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
Disease	Eye Abnormalities	BMPR1A CRPPA	5.24e-04	17	59	2	C0015393
Disease	otitis media (biomarker_via_orthology)	MUC4 MUC5AC	5.24e-04	17	59	2	DOID:10754 (biomarker_via_orthology)
Disease	Febrile seizure (within the age range of 3 months to 6 years)	HERC1 BSN	5.89e-04	18	59	2	HP_0002373
Disease	FEV/FEC ratio	THSD4 EFEMP1 ZNF781 LMX1B SCAPER CRPPA HERC1 FST ADAM12	7.01e-04	1228	59	9	EFO_0004713
Disease	influenza A (H1N1)	SLITRK4 ADAM12 LRP1B	7.14e-04	87	59	3	EFO_1001488
Disease	S-warfarin measurement	ADAM7 ADAM12 LRP1B	9.80e-04	97	59	3	EFO_0803323
Disease	ocular sarcoidosis	KCNH7 LRP2 AMBRA1	1.64e-03	116	59	3	EFO_0010723
Disease	sleep quality	DTD1 MYO9B LRP1B	1.72e-03	118	59	3	EFO_0005272
Disease	body surface area	GIPR EFEMP1 MYO9B KCNH2 SLIT3 PKHD1	1.77e-03	643	59	6	EFO_0022196
Disease	heart conduction disease (implicated_via_orthology)	KCNH7 KCNH2	1.88e-03	32	59	2	DOID:10273 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KVYISTNCPSQCNEN	ADAM7	626	Q9H2U9
QQVAAQFCSYQSIAL	ARHGEF11	826	O15085
CYNGICQTHEQQCVT	ADAM12	521	O43184
SESCQQERSCQYLQV	DLGAP1	306	O14490
CRTAQIVTQYCVGAN	GIPR	216	P48546
TDVQLVTQQVIQCAY	GIT2	726	Q14161
NVLVQNCKIYNDASC	AMBRA1	881	Q9C0C7
ISSNYCNCSSIQCNV	RAD51AP2	346	Q09MP3
ICYVSRNIQNNVSCY	OSMR	166	Q99650
ILDQCYNFVCVNVTT	CRPPA	331	A4D126
IAASFCNTVQQLYVC	SLC16A1	101	P53985
CNAESQCLYNQTSRV	MUC4	5036	Q99102
LLSNCQQLNCQYKCT	LRP1B	116	Q9NZR2
LQFQVTNYCVRVCAT	KIAA0825	591	Q8IV33
IANARVQNCAIIYCN	KCNH7	31	Q9NS40
NTKNSQPQCIVCVNY	HIF1A	326	Q16665
QTVIYQASQALNCCV	ANLN	731	Q9NQW6
QVICGQNCTFVIQAN	HERC1	4031	Q15751
IANARVENCAVIYCN	KCNH2	31	Q12809
NYNTCTTCRLQVCNL	BSN	481	Q9UPA5
CASLQAYAALCAQQN	MUC2	4731	Q02817
GCLYQTCQQNQFTCQ	LRP2	3026	P98164
NYEIRIQCCETVNVC	MUC5AC	2036	P98088
SSTCVVDQTNNAYCV	FST	176	P19883
VDQTNNAYCVTCNRI	FST	181	P19883
KYQTLNCSVNVNCVN	ITGA6	961	P23229
ISQYATICQQLQAEV	KIF18B	366	Q86Y91
YRIQCCTSTVNQAQV	PRG3	146	Q9Y2Y8
VDGNVSTIYCQNLCL	KAT6A	581	Q92794
QYEILCVSQFTLQCV	DTD1	71	Q8TEA8
NNVLIQYTNACVKVC	EXOC5	566	O00471
YAAQCIAKLLQQCTT	BTAF1	896	O14981
TIECCRTNLCNQYLQ	BMPR1A	121	P36894
LQIQCYQCEEFQLNN	LYPD1	21	Q8N2G4
SLCNAINVYNLTCNN	SCAPER	986	Q9BY12
INVYNLTCNNCSENC	SCAPER	991	Q9BY12
NTTLNVYLCQSENSC	PKD1L1	376	Q8TDX9
QLIQEFCQEYLNQCC	CAMSAP2	291	Q08AD1
VYQCNSLEQAQAICK	ITGB1BP1	171	O14713
QQCYNILGSFICQCN	EFEMP1	266	Q12805
ICNVCSCVSVENVLY	SLITRK4	26	Q8IW52
SVENIQSPCCSQAIY	PHF7	171	Q9BWX1
RVYQCNICSKIFQNS	PRDM15	736	P57071
CKVIFSNQTNVVCQT	PKHD1	971	P08F94
YECQNGAQCIVVQQE	SLIT3	1126	O75094
CCYVFSAQQLQAAQV	NOD2	561	Q9HC29
NVSSFQQAYITCLCS	RLF	246	Q13129
VCQSETCQRYLQAAI	SPATA12	76	Q7Z6I5
VQESQYQCLECGQLL	ZNF574	71	Q6ZN55
LVNFGNTCYCNSVLQ	USP12	41	O75317
FNEAQCNTAYQCLLI	TP53BP1	1791	Q12888
VVINFQAYCCILQDC	PKHD1L1	2996	Q86WI1
ECYNGLNQCLTTTQN	ZNF492	96	Q9P255
EVQKVCNICVLYQTS	UBE3B	456	Q7Z3V4
LQNYQFTNSEVTCQC	XPOT	191	O43592
YCKLCNVTLNSAQQA	ZMAT3	71	Q9HA38
SQTLQSQRQYACELC	ZBTB49	386	Q6ZSB9
NCNVVVQARLCVYNY	THSD4	981	Q6ZMP0
VAETACNFQLTQYQI	ZNF781	11	Q8N8C0
QVQCNSCKTSAIPQY	ZMYM4	576	Q5VZL5
NCSTCQNTACIIYSV	INSYN2B	461	A6NMK8
LQCAACQQALTTSCY	LMX1B	81	O60663
ASYQVSIPQSCEQCL	MYO9B	1636	Q13459