Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	HCN4 HCN2	3.31e-04	10	55	2	GO:0005222
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	HCN4 HCN2	5.70e-04	13	55	2	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	HCN4 HCN2	5.70e-04	13	55	2	GO:0043855
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HIVEP3 TCF4 HOXD3 HOXD10 NFATC4 FOXI3 TAL1 NKRF TBX2 NPAS2	1.90e-03	1244	55	10	GO:0000978
GeneOntologyMolecularFunction	structural constituent of nuclear pore	POM121 POM121C	2.15e-03	25	55	2	GO:0017056
GeneOntologyMolecularFunction	cAMP binding	HCN4 HCN2	2.15e-03	25	55	2	GO:0030552
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HIVEP3 TCF4 HOXD3 HOXD10 NFATC4 FOXI3 TAL1 NKRF TBX2 NPAS2	2.23e-03	1271	55	10	GO:0000987
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	HCN4 HCN2	2.32e-03	26	55	2	GO:0005248
GeneOntologyMolecularFunction	nuclear localization sequence binding	POM121 POM121C	2.50e-03	27	55	2	GO:0008139
GeneOntologyCellularComponent	HCN channel complex	HCN4 HCN2	3.92e-05	4	54	2	GO:0098855
GeneOntologyCellularComponent	nuclear pore	POM121 NUP210L NUP42 POM121C	1.35e-04	101	54	4	GO:0005643
GeneOntologyCellularComponent	outer dynein arm	DNAI1 DNAH9	4.25e-04	12	54	2	GO:0036157
GeneOntologyCellularComponent	transcription regulator complex	TCF4 HOXD10 NFATC4 ASCC3 TAL1 TBX2 NPAS2	8.19e-04	596	54	7	GO:0005667
Domain	Ion_trans_N	HCN4 HCN2	4.72e-05	4	53	2	PF08412
Domain	Ion_trans_N	HCN4 HCN2	4.72e-05	4	53	2	IPR013621
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN4 HCN2	7.03e-04	14	53	2	IPR003938
Domain	cNMP-bd_CS	HCN4 HCN2	9.24e-04	16	53	2	IPR018488
Domain	IPT	NFATC4 PLXNA2	2.65e-03	27	53	2	SM00429
Domain	Ig_E-set	NFATC4 ASCC3 PLXNA2	3.21e-03	104	53	3	IPR014756
Domain	TIG	NFATC4 PLXNA2	3.49e-03	31	53	2	PF01833
Domain	-	TCF4 TAL1 NPAS2	3.66e-03	109	53	3	4.10.280.10
Domain	CNMP_BINDING_1	HCN4 HCN2	3.71e-03	32	53	2	PS00888
Domain	CNMP_BINDING_2	HCN4 HCN2	3.71e-03	32	53	2	PS00889
Domain	IPT	NFATC4 PLXNA2	3.71e-03	32	53	2	IPR002909
Domain	HLH	TCF4 TAL1 NPAS2	3.86e-03	111	53	3	PF00010
Domain	cNMP	HCN4 HCN2	4.18e-03	34	53	2	SM00100
Domain	cNMP_binding	HCN4 HCN2	4.18e-03	34	53	2	PF00027
Domain	HLH	TCF4 TAL1 NPAS2	4.36e-03	116	53	3	SM00353
Domain	cNMP-bd_dom	HCN4 HCN2	4.43e-03	35	53	2	IPR000595
Domain	CNMP_BINDING_3	HCN4 HCN2	4.43e-03	35	53	2	PS50042
Domain	BHLH	TCF4 TAL1 NPAS2	4.47e-03	117	53	3	PS50888
Domain	bHLH_dom	TCF4 TAL1 NPAS2	4.58e-03	118	53	3	IPR011598
Domain	cNMP-bd-like	HCN4 HCN2	5.20e-03	38	53	2	IPR018490
Domain	-	HCN4 HCN2	8.20e-03	48	53	2	2.60.120.10
Pathway	REACTOME_SLC_TRANSPORTER_DISORDERS	HK1 POM121 NUP42 POM121C SLC2A2	9.46e-06	99	41	5	M27474
Pathway	REACTOME_GLUCOSE_METABOLISM	HK1 POM121 NUP42 POM121C	9.14e-05	82	41	4	MM15394
Pathway	REACTOME_GLUCOSE_METABOLISM	HK1 POM121 NUP42 POM121C	1.05e-04	85	41	4	M1870
Pathway	REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN	POM121 NUP42 POM121C	1.07e-04	32	41	3	M29579
Pathway	REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS	POM121 NUP42 POM121C	1.17e-04	33	41	3	M27016
Pathway	REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN	POM121 NUP42 POM121C	1.28e-04	34	41	3	M27041
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	POM121 NUP42 POM121C	1.40e-04	35	41	3	M27320
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	POM121 NUP42 POM121C	1.53e-04	36	41	3	M27245
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	POM121 NUP42 POM121C	1.53e-04	36	41	3	M26974
Pathway	REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS	HK1 POM121 NUP42 POM121C SLC2A2	1.53e-04	177	41	5	M27476
Pathway	REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS	POM121 NUP42 POM121C	1.66e-04	37	41	3	M1029
Pathway	REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS	POM121 NUP42 POM121C	1.66e-04	37	41	3	M27038
Pathway	WP_GLP1_IN_PANCREATIC_ISLET_CELLS	IL6 SLC2A2	1.72e-04	7	41	2	M48339
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	POM121 NUP42 POM121C	1.94e-04	39	41	3	M27238
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	POM121 NUP42 POM121C	2.09e-04	40	41	3	MM14945
Pathway	REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS	POM121 NUP42 POM121C	2.25e-04	41	41	3	M29574
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	POM121 NUP42 POM121C	2.25e-04	41	41	3	MM15200
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	POM121 NUP42 POM121C	2.42e-04	42	41	3	MM15039
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	POM121 NUP42 POM121C	2.60e-04	43	41	3	MM14609
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	POM121 NUP42 POM121C	2.60e-04	43	41	3	M26975
Pathway	REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS	POM121 NUP42 POM121C	2.78e-04	44	41	3	M109
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	POM121 NUP42 POM121C	3.18e-04	46	41	3	M27397
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	POM121 NUP42 POM121C	3.39e-04	47	41	3	MM14939
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	POM121 NUP42 POM121C	3.39e-04	47	41	3	M27395
Pathway	REACTOME_GENE_SILENCING_BY_RNA	POM121 NUP42 POM121C	3.83e-04	49	41	3	MM14837
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	POM121 NUP42 POM121C	4.07e-04	50	41	3	MM14610
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	POM121 NUP42 POM121C	4.32e-04	51	41	3	MM15151
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	POM121 NUP42 POM121C	4.84e-04	53	41	3	M27212
Pathway	REACTOME_SNRNP_ASSEMBLY	POM121 NUP42 POM121C	5.11e-04	54	41	3	M29594
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	POM121 NUP42 POM121C	5.39e-04	55	41	3	MM14917
Pathway	REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS	POM121 APOBEC3G NUP42 POM121C	5.53e-04	131	41	4	M5283
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	POM121 NUP42 POM121C	6.31e-04	58	41	3	MM15149
Pathway	REACTOME_SNRNP_ASSEMBLY	POM121 NUP42 POM121C	6.31e-04	58	41	3	MM14736
Pathway	WP_LACTATE_SHUTTLE_IN_GLIAL_CELLS	HK1 SLC16A7	6.31e-04	13	41	2	M48056
Pathway	REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS	POM121 NUP42 POM121C	6.63e-04	59	41	3	M27606
Pathway	WP_DISORDERS_OF_FRUCTOSE_METABOLISM	HK1 SLC2A2	7.35e-04	14	41	2	M45540
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	POM121 NUP42 POM121C	8.80e-04	65	41	3	MM15147
Pathway	WP_CORI_CYCLE	HK1 SLC2A2	1.09e-03	17	41	2	M39604
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	POM121 NUP42 POM121C	1.14e-03	71	41	3	M27394
Pathway	WP_GENES_TARGETED_BY_MIRNAS_IN_ADIPOCYTES	HCN4 HCN2	1.23e-03	18	41	2	M39405
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	POM121 NUP42 POM121C	1.23e-03	73	41	3	MM14948
Pathway	REACTOME_ISG15_ANTIVIRAL_MECHANISM	POM121 NUP42 POM121C	1.28e-03	74	41	3	M48006
Pathway	REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS	POM121 NUP42 POM121C	1.44e-03	77	41	3	M27226
Pathway	REACTOME_PI_3K_CASCADE_FGFR4	GAB1 KLB	1.52e-03	20	41	2	M27525
Pathway	REACTOME_PI_3K_CASCADE_FGFR4	GAB1 KLB	1.52e-03	20	41	2	MM15251
Pathway	WP_PATHOGENESIS_OF_SARSCOV2_MEDIATED_BY_NSP9NSP10_COMPLEX	IL6 NKRF	1.67e-03	21	41	2	M39876
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	POM121 NUP42 POM121C	1.72e-03	82	41	3	M27250
Pathway	REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS	POM121 NUP42 POM121C	1.85e-03	84	41	3	MM14929
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	POM121 NUP42 POM121C	1.85e-03	84	41	3	M725
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	POM121 NUP42 POM121C	1.98e-03	86	41	3	MM15413
Pathway	REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION	POM121 POM121C	2.19e-03	24	41	2	MM15658
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	POM121 NUP42 POM121C	2.40e-03	92	41	3	MM14951
Pathway	REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR4	GAB1 KLB	2.57e-03	26	41	2	MM15249
Pathway	REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR4	GAB1 KLB	2.77e-03	27	41	2	M27523
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAI1 DNAH9	2.77e-03	27	41	2	M47755
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	POM121 NUP42 POM121C	3.12e-03	101	41	3	M27253
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	POM121 NUP42 POM121C	3.58e-03	106	41	3	M27458
Pathway	WP_PRADERWILLI_AND_ANGELMAN_SYNDROME	POM121 NUP42 PCM1	3.87e-03	109	41	3	M39542
Pathway	REACTOME_TRNA_PROCESSING	POM121 NUP42 POM121C	4.07e-03	111	41	3	M27684
Pubmed	Compartmental distribution of hyperpolarization-activated cyclic-nucleotide-gated channel 2 and hyperpolarization-activated cyclic-nucleotide-gated channel 4 in thalamic reticular and thalamocortical relay neurons.	HCN4 HCN2	2.55e-06	2	56	2	16806719
Pubmed	The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.	HCN4 HCN2	2.55e-06	2	56	2	30877792
Pubmed	APOBEC3B and IL-6 form a positive feedback loop in hepatocellular carcinoma cells.	APOBEC3G IL6	2.55e-06	2	56	2	28646470
Pubmed	Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells.	HCN4 HCN2	2.55e-06	2	56	2	12194012
Pubmed	Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels.	HCN4 HCN2	2.55e-06	2	56	2	19574228
Pubmed	HCN2 and HCN4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels.	HCN4 HCN2	2.55e-06	2	56	2	17553794
Pubmed	Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4.	HCN4 HCN2	2.55e-06	2	56	2	12813043
Pubmed	Two pacemaker channels from human heart with profoundly different activation kinetics.	HCN4 HCN2	2.55e-06	2	56	2	10228147
Pubmed	Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels.	HCN4 HCN2	2.55e-06	2	56	2	16777944
Pubmed	Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias.	HCN4 HCN2	2.55e-06	2	56	2	15687126
Pubmed	Control of heart rate by cAMP sensitivity of HCN channels.	HCN4 HCN2	2.55e-06	2	56	2	19570998
Pubmed	KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents.	HCN4 HCN2	7.63e-06	3	56	2	12856183
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121 POM121C	7.63e-06	3	56	2	30802453
Pubmed	Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.	HCN4 HCN2	7.63e-06	3	56	2	22652004
Pubmed	Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.	HCN4 HCN2	7.63e-06	3	56	2	21187420
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121 POM121C	7.63e-06	3	56	2	35507432
Pubmed	Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart.	HCN4 HCN2	7.63e-06	3	56	2	21945247
Pubmed	A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase.	HCN4 HCN2	7.63e-06	3	56	2	16079136
Pubmed	Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN2	7.63e-06	3	56	2	22006928
Pubmed	HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age-dependent changes.	HCN4 HCN2	7.63e-06	3	56	2	33181864
Pubmed	Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.	DNAI1 DNAH9	7.63e-06	3	56	2	15750039
Pubmed	Transcriptional control of pacemaker channel genes HCN2 and HCN4 by Sp1 and implications in re-expression of these genes in hypertrophied myocytes.	HCN4 HCN2	7.63e-06	3	56	2	19471099
Pubmed	A census of human transcription factors: function, expression and evolution.	HIVEP3 TCF4 HOXD3 HOXD10 NFATC4 FOXI3 TAL1 TBX2 NPAS2	1.37e-05	908	56	9	19274049
Pubmed	The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.	POM121 PRRC2C POM121C	1.40e-05	29	56	3	17577209
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HIVEP3 PRUNE2 POM121 PLEKHG3 RALGAPA2 POM121C PTGFRN	1.40e-05	493	56	7	15368895
Pubmed	Functional expression of the human HCN3 channel.	HCN4 HCN2	1.52e-05	4	56	2	16043489
Pubmed	PDK1-AKT signaling pathway regulates the expression and function of cardiac hyperpolarization-activated cyclic nucleotide-modulated channels.	HCN4 HCN2	1.52e-05	4	56	2	32184125
Pubmed	Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.	HCN4 HCN2	1.52e-05	4	56	2	9405696
Pubmed	Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN2	1.52e-05	4	56	2	12928435
Pubmed	Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.	POM121 POM121C	1.52e-05	4	56	2	17900573
Pubmed	Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.	HCN4 HCN2	1.52e-05	4	56	2	20140458
Pubmed	Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.	HCN4 HCN2	1.52e-05	4	56	2	22748890
Pubmed	SCL binds the human homologue of DRG in vivo.	TCF4 TAL1	1.52e-05	4	56	2	9824680
Pubmed	Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr.	HOXD3 HOXD10	1.52e-05	4	56	2	29042517
Pubmed	Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.	HCN4 HCN2	1.52e-05	4	56	2	9630217
Pubmed	DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.	DNAI1 DNAH9	1.52e-05	4	56	2	18950741
Pubmed	Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.	HCN4 HCN2	1.52e-05	4	56	2	21615589
Pubmed	Determinants of helix-loop-helix dimerization affinity. Random mutational analysis of SCL/tal.	TCF4 TAL1	1.52e-05	4	56	2	8576241
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	IGF2BP1 POM121 PRRC2C ADD3	2.19e-05	101	56	4	26949739
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ASCC3 SNX29 PCM1 GAB1 ADD3	2.22e-05	209	56	5	36779422
Pubmed	Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.	HCN4 HCN2	2.54e-05	5	56	2	15564593
Pubmed	Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.	HCN4 HCN2	2.54e-05	5	56	2	34429357
Pubmed	Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis.	TCF4 TAL1	2.54e-05	5	56	2	20231428
Pubmed	The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.	DNAI1 DNAH9	2.54e-05	5	56	2	23525783
Pubmed	Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex.	POM121 NUP42	2.54e-05	5	56	2	9621063
Pubmed	Peering through the pore: nuclear pore complex structure, assembly, and function.	POM121 NUP42 POM121C	3.20e-05	38	56	3	12791264
Pubmed	Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.	HCN4 HCN2	3.80e-05	6	56	2	25761792
Pubmed	Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation.	TCF4 NFATC4	3.80e-05	6	56	2	21880741
Pubmed	Effect of vaginal immunization with HIVgp140 and HSP70 on HIV-1 replication and innate and T cell adaptive immunity in women.	APOBEC3G IL6	3.80e-05	6	56	2	25008917
Pubmed	Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation.	HOXD3 HOXD10	3.80e-05	6	56	2	2574828
Pubmed	Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation.	HCN4 HCN2	3.80e-05	6	56	2	26005035
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	PRRC2C NUP42 POM121C DNAH9	4.75e-05	123	56	4	26912792
Pubmed	Proteome analysis of the HIV-1 Gag interactome.	IGF2BP1 PRRC2C NKRF	5.00e-05	44	56	3	25010285
Pubmed	An update of mouse and human HOX gene nomenclature.	HOXD3 HOXD10	5.32e-05	7	56	2	1973145
Pubmed	Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis.	HCN4 TBX2	5.32e-05	7	56	2	22203979
Pubmed	Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.	HCN4 HCN2	5.32e-05	7	56	2	27956497
Pubmed	Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.	HCN4 HCN2	5.32e-05	7	56	2	19421833
Pubmed	Uncoupling time and space in the collinear regulation of Hox genes.	HOXD3 HOXD10	5.32e-05	7	56	2	19266017
Pubmed	The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors.	PCM1 RHO	7.09e-05	8	56	2	22031837
Pubmed	Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster.	HOXD3 HOXD10	7.09e-05	8	56	2	10364522
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	PRRC2C AHNAK FAM98A ASCC3 PCM1	7.25e-05	268	56	5	33024031
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	TCF4 HOXD3 HOXD10 NFATC4 TAL1 NKRF TBX2 NPAS2	7.71e-05	877	56	8	20211142
Pubmed	Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.	IGF2BP1 PRRC2C FAM98A	8.26e-05	52	56	3	26265008
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ATP5F1D IGF2BP1 HK1 PLEKHG3 PRRC2C AHNAK ASCC3 PTGFRN NKRF PCM1	8.98e-05	1440	56	10	30833792
Pubmed	The thyroid transcription factor-1 gene is a candidate target for regulation by Hox proteins.	HOXD3 HOXD10	9.10e-05	9	56	2	7913891
Pubmed	Anterior-posterior differences in HoxD chromatin topology in limb development.	HOXD3 HOXD10	9.10e-05	9	56	2	22872084
Pubmed	Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes.	IL6 SLC2A2	9.10e-05	9	56	2	17192490
Pubmed	Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma.	HK1 SLC2A2	9.10e-05	9	56	2	19554504
Pubmed	Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters.	HOXD3 HOXD10	9.10e-05	9	56	2	22278926
Pubmed	HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation.	HOXD3 HOXD10	9.10e-05	9	56	2	8890171
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	IGF2BP1 PRRC2C FAM98A ASCC3 NKRF PCM1	9.85e-05	462	56	6	31138677
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	IGSF10 TCF4 RALGAPA2 IL6 SLC2A2 GAB1 NPAS2	1.13e-04	686	56	7	29987050
Pubmed	International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.	HCN4 HCN2	1.14e-04	10	56	2	16382102
Pubmed	Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations.	HOXD3 HOXD10	1.14e-04	10	56	2	11544178
Pubmed	MyoR modulates cardiac conduction by repressing Gata4.	HCN4 TBX2	1.14e-04	10	56	2	25487574
Pubmed	Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31-->q32.1.	HOXD3 HOXD10	1.14e-04	10	56	2	11060466
Pubmed	Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis.	PLXNA2 TBX2	1.14e-04	10	56	2	17519333
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	IGF2BP1 PRRC2C AHNAK POM121C SNX29 NKRF PCM1 ADD3	1.19e-04	934	56	8	33916271
Pubmed	Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis.	NFATC4 TBX2	1.39e-04	11	56	2	20824138
Pubmed	Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.	DNAI1 DNAH9	1.39e-04	11	56	2	24421334
Pubmed	Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.	HCN4 HCN2	1.66e-04	12	56	2	17482496
Pubmed	NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function.	HCN4 HCN2	1.66e-04	12	56	2	14633990
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	IGF2BP1 PRRC2C AHNAK ASCC3 PCM1	1.92e-04	330	56	5	32529326
Pubmed	KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.	DNAI1 RHO	1.96e-04	13	56	2	21177258
Pubmed	The SWI/SNF BAF-A complex is essential for neural crest development.	HOXD3 PLXNA2	1.96e-04	13	56	2	26806701
Pubmed	Tulp1 is involved in specific photoreceptor protein transport pathways.	NUP42 RHO	1.96e-04	13	56	2	22183407
Pubmed	Hox gene function in vertebrate gut morphogenesis: the case of the caecum.	HOXD3 HOXD10	1.96e-04	13	56	2	17942481
Pubmed	Differential interactions of Id proteins with basic-helix-loop-helix transcription factors.	TCF4 TAL1	1.96e-04	13	56	2	9242638
Pubmed	Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.	TCF4 SLC2A2	2.29e-04	14	56	2	15226261
Pubmed	The mouse Ulnaless mutation deregulates posterior HoxD gene expression and alters appendicular patterning.	HOXD3 HOXD10	2.29e-04	14	56	2	9342041
Pubmed	Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system.	HCN4 TBX2	2.29e-04	14	56	2	18467625
Pubmed	Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.	HCN4 HCN2	2.29e-04	14	56	2	29107716
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	TCF4 HOXD3 HOXD10 NFATC4 TBX2 NPAS2	2.38e-04	544	56	6	28473536
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SMAP1 IGF2BP1 HK1 AHNAK PCM1 GAB1 ADD3	2.42e-04	777	56	7	35844135
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PRRC2C AHNAK ASCC3 NKRF PCM1 ADD3	2.50e-04	549	56	6	38280479
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	HOXD3 HOXD10 NFATC4 TBX2	2.59e-04	191	56	4	24146773
Pubmed	Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation.	HCN4 HCN2	2.64e-04	15	56	2	21147989
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	POM121 POM121C	2.64e-04	15	56	2	14697343
Pubmed	Probing nuclear pore complex architecture with proximity-dependent biotinylation.	HIVEP3 POM121 NUP42	2.66e-04	77	56	3	24927568
Pubmed	Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice.	HCN4 TBX2	3.01e-04	16	56	2	21266775
Cytoband	Ensembl 112 genes in cytogenetic band chr2q31	HOXD3 HOXD10 ZNF385B	1.37e-03	178	56	3	chr2q31
GeneFamily	Cyclic nucleotide gated channels	HCN4 HCN2	2.02e-04	10	39	2	250
GeneFamily	Dyneins, axonemal	DNAI1 DNAH9	6.04e-04	17	39	2	536
GeneFamily	Basic helix-loop-helix proteins	TCF4 TAL1 NPAS2	1.71e-03	110	39	3	420
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRRC2C AHNAK RNF180 PTGFRN SLC16A7 PLXNA2	1.88e-07	199	56	6	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 PRRC2C AHNAK ASCC3 PCM1	2.81e-06	176	56	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	HIVEP3 SNX29P2 HCN2 SNX29 IL6	2.97e-06	178	56	5	71ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 PRRC2C AHNAK TAL1 ADD3	3.14e-06	180	56	5	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 PRRC2C AHNAK TAL1 ADD3	3.14e-06	180	56	5	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 PRRC2C AHNAK ASCC3 PCM1	3.49e-06	184	56	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDHR3 SNX29 SLC2A2 NPAS2	3.68e-06	186	56	5	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDHR3 SNX29 SLC2A2 NPAS2	3.78e-06	187	56	5	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDHR3 SNX29 SLC2A2 NPAS2	4.19e-06	191	56	5	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDHR3 SNX29 SLC2A2 NPAS2	4.19e-06	191	56	5	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 PLEKHG3 AHNAK PTGFRN ADD3	4.30e-06	192	56	5	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 PLEKHG3 AHNAK PTGFRN ADD3	4.30e-06	192	56	5	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGSF10 DNAI1 CDHR3 DNAH9 PLXNA2	4.41e-06	193	56	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFNGR2 TCF4 AHNAK SNX29 IL6	4.52e-06	194	56	5	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	5'-Adult-LymphNode-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF4 HOXD3 HOXD10 RALGAPA2 TAL1	5.00e-06	198	56	5	d7e15e61b6018e4c36461c9471ee29601929925c
ToppCell	LPS_IL1RA\|World / Treatment groups by lineage, cell group, cell type	TCF4 PRRC2C ASCC3 RALGAPA2 IL6	5.25e-06	200	56	5	a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCell	Ciliated_cells-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAI1 HCN4 NAP1L3 DNAH9	3.71e-05	149	56	4	6399c5a2f06d79f020dece252526f1c0c110d569
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DNAI1 CDHR3 FOXI3 DNAH9	3.91e-05	151	56	4	8216462e723fec2797387929dde095370947e10a
ToppCell	frontal_cortex-Non-neuronal-smooth_muscle_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NFATC4 PLEKHG3 AHNAK TBX2	4.66e-05	158	56	4	08806240228c5b780f5aef92ce2c278ae4d797cc
ToppCell	frontal_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NFATC4 PLEKHG3 AHNAK TBX2	4.66e-05	158	56	4	496b6988f7b3439968351840ae22f56ffa1643f1
ToppCell	frontal_cortex-Non-neuronal-smooth_muscle_cell-SMC\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NFATC4 PLEKHG3 AHNAK TBX2	4.66e-05	158	56	4	5b3d30f92b619f14a7b48502170000fa5783358a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 NUP210L PGBD5 KLB	5.02e-05	161	56	4	4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell	primary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NFATC4 PLEKHG3 AHNAK TBX2	5.39e-05	164	56	4	9eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCell	primary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NFATC4 PLEKHG3 AHNAK TBX2	5.39e-05	164	56	4	f510f20e37e31b486cdd0e3f597ce4ff00877c5d
ToppCell	primary_visual_cortex-Non-neuronal-smooth_muscle_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NFATC4 PLEKHG3 AHNAK TBX2	5.39e-05	164	56	4	5c932a462cbf81d029c8d11ec3aea3191529527b
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAI1 CDHR3 DNAH9 PGBD5	5.39e-05	164	56	4	9e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HOXD3 HOXD10 PLEKHG3 PLXNA2	5.52e-05	165	56	4	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXD10 NUP210L KLB NPAS2	6.06e-05	169	56	4	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAI1 HCN4 CDHR3 DNAH9	6.06e-05	169	56	4	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRUNE2 CDHR3 PTGFRN RHO	6.34e-05	171	56	4	9e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCell	droplet-Kidney-KIDNEY-1m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CDHR3 NUP42 NKRF	6.34e-05	171	56	4	d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NUP210L TAL1 NKRF PLXNA2	6.63e-05	173	56	4	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUP210L PRRC2C ASCC3 PCM1	7.41e-05	178	56	4	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 HCN4 DNAH9 KLB	7.41e-05	178	56	4	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 TCF4 AHNAK SNX29	7.74e-05	180	56	4	df60970520fba2ac0639faa54096766d07418ca4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAI1 CDHR3 DNAH9 PCM1	7.74e-05	180	56	4	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	10x5'-bone_marrow-Lymphocytic_B-Pre-B\|bone_marrow / Manually curated celltypes from each tissue	TCF4 NFATC4 CDHR3 GAB1	8.07e-05	182	56	4	a5fd392178c2f533e265d2e3ce63b90c2553e4c1
ToppCell	B_cells-Naive_B_cells_\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TCF4 SNX29P2 SNX29 IL6	8.07e-05	182	56	4	63c3b63315276b66667d49fab09661ac320e7a36
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXD3 HOXD10 RALGAPA2 TAL1	8.25e-05	183	56	4	2d0d3b486498a7903fa9a1f48b189291da49c430
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	TCF4 NAP1L3 TAL1 IL6	8.60e-05	185	56	4	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK1 PCDHGB7 HOXD10 SLC16A7	8.60e-05	185	56	4	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCDHGB7 PTGFRN IL6 ADD3	8.60e-05	185	56	4	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TCF4 RALGAPA2 TAL1 TBX2	8.78e-05	186	56	4	f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell	10x5'-Liver-Lymphocytic_B-Naive_B_cells\|Liver / Manually curated celltypes from each tissue	TCF4 SNX29 IL6 GAB1	8.78e-05	186	56	4	23efdcedbe67f5e6c59106e052f570cd0338f1c1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SNX29 SLC2A2 NPAS2	8.78e-05	186	56	4	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|356C / Donor, Lineage, Cell class and subclass (all cells)	TCF4 RALGAPA2 TAL1 TBX2	8.78e-05	186	56	4	2b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFATC4 APOBEC3G RNF180 TBX2	8.96e-05	187	56	4	150023e6a50c9da461f2321074d2d5e96caafb06
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	IGF2BP1 NFATC4 TBX2	9.03e-05	69	56	3	a157b1582401cebd222343d94086dbea876140c2
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	IGF2BP1 NFATC4 TBX2	9.03e-05	69	56	3	cdd42abdd072aa438830d837ee857529269a81e0
ToppCell	ILEUM-non-inflamed-(5)_Plasma-(5)_IgG_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TCF4 PRRC2C CDHR3 SLC16A7	9.15e-05	188	56	4	2156f1bc849ff1cb09ae296d13bedd913ae6b43b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDHR3 ZNF385B SLC2A2	9.34e-05	189	56	4	28b502611829e4a24caff2562545c7db97686099
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TCF4 HOXD3 HOXD10 TAL1	9.53e-05	190	56	4	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXD3 HOXD10 RALGAPA2 TAL1	9.53e-05	190	56	4	6b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAI1 PLXNA2 ADD3 TBX2	9.73e-05	191	56	4	df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCell	(12)_SLC16A7+\|World / shred by cell type by condition	DNAI1 IGF2BP1 CDHR3 DNAH9	9.73e-05	191	56	4	e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXD10 TAL1 IL6 PLXNA2	9.92e-05	192	56	4	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXD10 TAL1 IL6 PLXNA2	9.92e-05	192	56	4	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK1 AHNAK TAL1 PTGFRN	9.92e-05	192	56	4	a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFNGR2 TCF4 AHNAK SNX29	1.01e-04	193	56	4	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B-Naive_B_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	TCF4 SNX29 IL6 GAB1	1.01e-04	193	56	4	eb497d62a45ad77b2578b03a84cb3edc83207be5
ToppCell	LAM-Epithelial-AirwayEpi\|Epithelial / Condition, Lineage and Cell class	DNAI1 TCF4 CDHR3 DNAH9	1.01e-04	193	56	4	f2672d2c495ee12c3b7d132452bde581fa5a7856
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 RALGAPA2 TAL1 PLXNA2	1.03e-04	194	56	4	a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFNGR2 TCF4 AHNAK SNX29	1.05e-04	195	56	4	481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFNGR2 TCF4 AHNAK SNX29	1.05e-04	195	56	4	6108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 RALGAPA2 IL6 PLXNA2	1.05e-04	195	56	4	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXD10 TAL1 IL6 PLXNA2	1.05e-04	195	56	4	4db30b3bc65c25626f828cd4f867f20c71809898
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C ASCC3 SLC2A2 PCM1	1.05e-04	195	56	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF4 PRRC2C PCM1 ADD3	1.05e-04	195	56	4	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C ASCC3 SLC2A2 PCM1	1.05e-04	195	56	4	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 PRRC2C ASCC3 PCM1	1.05e-04	195	56	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 RALGAPA2 IL6 PLXNA2	1.07e-04	196	56	4	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PRUNE2 AHNAK PTGFRN PLXNA2	1.07e-04	196	56	4	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 RALGAPA2 IL6 PLXNA2	1.07e-04	196	56	4	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 RALGAPA2 IL6 PLXNA2	1.07e-04	196	56	4	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	Endothelial\|World / Lineage, Cell type, age group and donor	TCF4 HOXD3 RALGAPA2 TAL1	1.07e-04	196	56	4	96c6d78482a130ce4e29f6629972a06d10d7530e
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAI1 CDHR3 DNAH9 PCM1	1.10e-04	197	56	4	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAI1 CDHR3 DNAH9 PCM1	1.10e-04	197	56	4	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAI1 CDHR3 DNAH9 PCM1	1.10e-04	197	56	4	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAI1 CDHR3 DNAH9 PCM1	1.10e-04	197	56	4	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HIVEP3 PLEKHG3 AHNAK APOBEC3G	1.12e-04	198	56	4	a6b942fe850e287e1cb705684e29218072daf891
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TCF4 HOXD3 PLEKHG3 TAL1	1.12e-04	198	56	4	9ab0db78394e730f6866b2db80047149024ad5f6
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF4 RALGAPA2 TAL1 IL6	1.12e-04	198	56	4	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TCF4 HOXD3 HOXD10 TAL1	1.12e-04	198	56	4	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TCF4 HOXD3 HOXD10 TAL1	1.12e-04	198	56	4	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TCF4 HOXD3 PLEKHG3 TAL1	1.12e-04	198	56	4	e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDHR3 AHNAK DNAH9 PCM1	1.12e-04	198	56	4	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Lymphatic\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	TCF4 HOXD10 TAL1 ADD3	1.14e-04	199	56	4	88f33b8dcd837abfa1d12c28719e073a7da6e979
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 HOXD10 TAL1 ADD3	1.14e-04	199	56	4	64b19aff72e2a109cb5857cb248bd4712dd49b43
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 HOXD10 TAL1 ADD3	1.14e-04	199	56	4	2b9e1e069b36b3a61cc3e384f4523687b0e03905
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	TCF4 NFATC4 PLEKHG3 TBX2	1.16e-04	200	56	4	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 NFATC4 PLEKHG3 TBX2	1.16e-04	200	56	4	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TCF4 NFATC4 PLEKHG3 TBX2	1.16e-04	200	56	4	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IGF2BP1 PCDHGB7 NUP210L	2.12e-04	92	56	3	d2c1d25e5bb6ba4f406e916e3c0a5ad05492e59d
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IGF2BP1 PCDHGB7 NUP210L	2.12e-04	92	56	3	926e02725a03d8473eda25d4aef63e34a6566224
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-D\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	HCN4 HCN2 KLB	2.40e-04	96	56	3	b671ae6a00b2f4ddf18d7a0b0cb15c34d9fb2a69
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IGF2BP1 NUP210L TBX2	2.63e-04	99	56	3	98c40a27432929434879c9e7283a14102f405f39
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IGF2BP1 NUP210L TBX2	2.63e-04	99	56	3	d6bd8075dc7aba2034ea78b1389868282bc80a2d
ToppCell	Hippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IGF2BP1 NFATC4 TBX2	5.33e-04	126	56	3	b0bc61be1d4ce8114077c524fedfdf89128bcf12
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NUP210L PLEKHG3 GAB1	6.52e-04	135	56	3	b444005987093efab3265201b3541d7941816cc2
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CDHR3 ZNF385B ADD3	7.70e-04	143	56	3	091708a47ac55c6585923ee30190ff296fa87f6f
Drug	Mutagens	IFNGR2 SMAP1 AHNAK FAM98A SNX29 RHO	7.52e-09	61	55	6	ctd:D009153
Drug	Carcinogens	IFNGR2 SMAP1 AHNAK FAM98A SNX29 RHO	1.84e-06	153	55	6	ctd:D002273
Drug	HNMPA-(AM)3; Down 200; 5uM; PC3; HG-U133A	NFATC4 PLEKHG3 GAB1 ADD3 RHO NPAS2	7.92e-06	197	55	6	583_DN
Drug	Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; HL60; HT_HG-U133A	PRUNE2 HOXD3 HOXD10 APOBEC3G PLXNA2 ZMYM6	8.15e-06	198	55	6	2999_DN
Drug	zatebradine	HCN4 HCN2	1.72e-05	3	55	2	ctd:C043636
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	HIVEP3 IGF2BP1 POM121C TAL1 SLC2A2	5.83e-04	364	55	5	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	neuroticism measurement, cognitive function measurement	IGF2BP1 NUP210L ZNF385B ASCC3 SNX29 NPAS2	6.34e-04	566	55	6	EFO_0007660, EFO_0008354
Disease	pulse pressure measurement	HIVEP3 TCF4 HOXD3 ZNF385B IL6 PCM1 TBX2 KLB NPAS2	1.01e-03	1392	55	9	EFO_0005763
Disease	Streptozotocin Diabetes	HK1 IL6 SLC2A2	1.09e-03	108	55	3	C0038433
Disease	Diabetes Mellitus, Experimental	HK1 IL6 SLC2A2	1.09e-03	108	55	3	C0011853
Disease	Alloxan Diabetes	HK1 IL6 SLC2A2	1.09e-03	108	55	3	C0002152
Disease	TYPE 2 DIABETES MELLITUS	IL6 SLC2A2	1.25e-03	28	55	2	125853
Disease	Type 2 diabetes mellitus	IL6 SLC2A2	1.25e-03	28	55	2	cv:C0011860
Disease	sleep apnea measurement	HK1 HOXD3 ZMYM6	1.34e-03	116	55	3	EFO_0007817
Disease	serum gamma-glutamyl transferase measurement	POM121 NUP210L AHNAK POM121C TAL1 SLC2A2 KLB	1.49e-03	914	55	7	EFO_0004532

Protein segments in the cluster

Peptide	Gene	Start	Entry
LEMSFAVPFFPQQSG	AMBN	21	Q9NP70
NSFSGFSSPPLSLGM	ADD3	101	Q9UEY8
SMDPPTFTFNFNNEP	APOBEC3G	196	Q9HC16
AAAPAAASGPNQMSF	ATP5F1D	26	P30049
AASGPNQMSFTFASP	ATP5F1D	31	P30049
PAFNMASPESDFGIN	AHNAK	5546	Q09666
KNPSFPEYMFSSNSG	DNAI1	371	Q9UI46
SNFGPIFMTIPAFFA	RHO	281	P08100
VPGDQMNPEFNFFTS	PCDHGB7	756	Q9Y5F8
QSTPAPMAQFSAQFS	NPAS2	486	Q99743
SPFSSPFHNFSMVNS	FOXI3	396	A8MTJ6
TPGTFDFSSFGMQVP	GAB1	476	Q13480
TGAAPYSSFMQAPEQ	IGF2BP1	391	Q9NZI8
PATSTFPSSFFMQDG	TCF4	206	P15884
IPGFTNFSSFAPGMN	PCM1	1126	Q15154
NFSSFAPGMNFSPLF	PCM1	1131	Q15154
PAAGMPQFSTFHSEN	PLXNA2	31	O75051
FMVAEFFSQGPRPAA	SLC2A2	421	P11168
MAGSPVFLSSLAPFN	SLC16A7	151	O60669
NFVESMAPASGPVFN	HOXD3	361	P31249
MTFEDFAAQVFSPSP	RALGAPA2	1851	Q2PPJ7
MPLGFTFSFPCQQTS	HK1	596	P19367
ASMPLFANADPNFVT	HCN4	591	Q9Y3Q4
PAFGFGSSQAATFMS	NUP42	216	O15504
GSSQAATFMSPGFPV	NUP42	221	O15504
ATFMSPGFPVNNSSS	NUP42	226	O15504
FGAPQASAASFTPAM	POM121C	841	A8CG34
AASFTPAMGSIFQFG	POM121	871	Q96HA1
MPPSASAVDFFQLFV	PGBD5	116	Q8N414
SAFISPQGFMAPFGS	IGSF10	301	Q6WRI0
SEAPNNRFNFTMPSG	CDHR3	376	Q6ZTQ4
MSFPNSSPAANTFLV	HOXD10	1	P28358
SMVQLFSSPFGYQSP	CAPRIN2	56	Q6IMN6
FTAASPSAGFPMDFN	IFNGR2	96	P38484
AFSFGPNNFKPLNTM	KLB	371	Q86Z14
FATSFEESGPATPMF	DNAH9	3886	Q9NYC9
SMPLFANADPNFVTA	HCN2	541	Q9UL51
MNSFSTSAFGPVAFS	IL6	1	P05231
GFFNSTSSPPHFMSL	NUP210L	1856	Q5VU65
NSYSFQNPSSFDPSM	RNF180	276	Q86T96
TFSMPFCGSSVIPQF	OR14A2	161	Q96R54
QPKPFFAAGNTFEMT	PTGFRN	556	Q9P2B2
MSAFESPFGPNSNGS	SNX29P2	151	Q8IUI4
VNIMSAFESPFGPNS	SNX29	301	Q8TEQ0
FDLFNFDPAPMASGQ	PRUNE2	491	Q8WUY3
FPSASATPFGTDMDF	NFATC4	701	Q14934
NMYFDSGNPAPSTTS	NKRF	131	O15226
SAGEMSPQRFFFNPS	PLEKHG3	1006	A1L390
FFGEPDAFPMFTTNN	TAL1	151	P17542
SKPPANITMFQFFSG	FAM98A	156	Q8NCA5
ANYNSFSSASMPQIP	PRRC2C	2291	Q9Y520
FGSASMASPANSFVG	TAOK3	166	Q9H2K8
NASFFNFFSPPEIPM	NAP1L3	436	Q99457
KQMFGPFPSSSATAA	ASCC3	116	Q8N3C0
MSAFLAAAQPSFFPA	TBX2	26	Q13207
PGQSPEFFSTQAMSS	HIVEP3	1156	Q5T1R4
FTSQAPAAFQGFPSM	SMAP1	331	Q8IYB5
SSAVGLFPNFNTMDP	ZNF385B	121	Q569K4
FPSFSEFSNSSGLNM	ZMYM6	1166	O95789
LMSSGYAGQFFQPAS	YIPF7	81	Q8N8F6