Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 RC3H2 ERVK-7 ERVK-10 ERVK-8 ERVK-11	5.31e-09	21	140	6	GO:0035613
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25	6.19e-09	37	140	7	GO:0004190
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	7.04e-09	11	140	5	GO:0004523
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25	7.54e-09	38	140	7	GO:0070001
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	3.00e-08	14	140	5	GO:0003964
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	5.74e-06	37	140	5	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	6.57e-06	38	140	5	GO:0034061
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.72e-05	46	140	5	GO:0016893
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.34e-04	79	140	5	GO:0004521
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-7 ERVK-10 OGG1 ERVK-8 ERVK-11	3.97e-04	136	140	6	GO:0004519
GeneOntologyMolecularFunction	osmolarity-sensing monoatomic cation channel activity	TMEM63C TMEM63A	4.81e-04	5	140	2	GO:1990760
GeneOntologyMolecularFunction	osmosensor activity	TMEM63C TMEM63A	7.19e-04	6	140	2	GO:0005034
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 ERVK-7 ERVK-10 OGG1 ERVK-8 TDP1 ERVK-11	1.24e-03	231	140	7	GO:0004518
GeneOntologyMolecularFunction	patched binding	CCNB1 SMO	1.33e-03	8	140	2	GO:0005113
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	RIMBP2 RIMS1	1.33e-03	8	140	2	GO:0098882
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	ERVK-6 PDE6C ARSJ LIPJ ERVK-7 ERVK-10 OGG1 TULP2 ARSD PTPRG PTPRK ERVK-8 TDP1 ERVK-11	1.63e-03	807	140	14	GO:0016788
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1D RIMBP2	1.70e-03	9	140	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1D RIMBP2	1.70e-03	9	140	2	GO:0099626
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8 SMARCB1 ERVK-11	1.45e-10	13	140	6	GO:0015074
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.82e-05	48	140	5	GO:0000731
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	IL15RA AFTPH HLA-DMB VPS13C UBR4 APOB ITGA2B DENND1A SLC12A2 CSF3R PLEKHM2 PI4KA SORCS2 MKLN1 LRP1 FMN2 SMO UNC13C KLHL12 ATG9A AP4B1 GPR151 TMEM63A	1.89e-05	1307	140	23	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	IL15RA AFTPH HLA-DMB VPS13C UBR4 APOB ITGA2B DENND1A SLC12A2 CSF3R PLEKHM2 PI4KA SORCS2 MKLN1 LRP1 FMN2 SMO UNC13C KLHL12 ATG9A AP4B1 GPR151 TMEM63A	2.35e-05	1325	140	23	GO:0012506
GeneOntologyCellularComponent	microtubule organizing center	TUBG2 UBR4 ARFGEF2 CILK1 HEPACAM2 CUL7 MDH1 CCNA2 CCNB1 FRY GLE1 PKHD1 LRP1 SMO KLHL12 HERC2 TMEM63A	1.43e-04	919	140	17	GO:0005815
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	RIMBP2 UNC13C RIMS1	4.72e-04	23	140	3	GO:0098831
GeneOntologyCellularComponent	synaptic membrane	CACNA1D CLSTN2 DENND1A CHRNA1 CHRNA2 SORCS2 MKLN1 LRP1 UNC13C RIMS1 ATG9A GPR151	5.64e-04	583	140	12	GO:0097060
Domain	APC_su10/DOC_dom	CUL9 CUL7 ANAPC10 HERC2	7.96e-08	7	131	4	IPR004939
Domain	DOC	CUL9 CUL7 ANAPC10 HERC2	7.96e-08	7	131	4	PS51284
Domain	ANAPC10	CUL9 CUL7 ANAPC10 HERC2	7.96e-08	7	131	4	PF03256
Domain	APC10	CUL9 CUL7 ANAPC10 HERC2	7.96e-08	7	131	4	SM01337
Domain	Galactose-bd-like	CUL9 CUL7 MEP1B ANAPC10 PTPRK MKLN1 HERC2 EPHA3	3.17e-07	94	131	8	IPR008979
Domain	Cul7	CUL9 CUL7 HERC2	3.37e-07	3	131	3	PF11515
Domain	CPH_domain	CUL9 CUL7 HERC2	3.37e-07	3	131	3	IPR021097
Domain	-	CHL1 HLA-DMB NXPE4 HEPACAM2 IL18R1 PKHD1L1 IGLL5 HEPACAM FCRL3 PTPRG CSF3R PTPRK PKHD1 RIMBP2 ADGRF5 KAZALD1 FCRL4 EPHA3	8.92e-07	663	131	18	2.60.40.10
Domain	Ig-like_fold	CHL1 HLA-DMB NXPE4 HEPACAM2 IL18R1 PKHD1L1 IGLL5 HEPACAM FCRL3 PTPRG CSF3R PTPRK PKHD1 RIMBP2 ADGRF5 KAZALD1 FCRL4 EPHA3	2.18e-06	706	131	18	IPR013783
Domain	-	CUL9 CUL7 ANAPC10 MKLN1 HERC2 EPHA3	1.23e-05	73	131	6	2.60.120.260
Domain	DUF5050	LRP1B LRP1	4.88e-05	2	131	2	IPR032485
Domain	DUF5050	LRP1B LRP1	4.88e-05	2	131	2	PF16472
Domain	ARM-type_fold	UBR4 MROH5 ARFGEF2 CUL9 APOB CUL7 PI4KA IPO13 AP4B1 TARBP1	1.41e-04	339	131	10	IPR016024
Domain	RSN1_7TM	TMEM63C TMEM63A	1.46e-04	3	131	2	IPR003864
Domain	PHM7_cyt	TMEM63C TMEM63A	1.46e-04	3	131	2	IPR027815
Domain	REELIN	FRRS1 SPON1	1.46e-04	3	131	2	PS51019
Domain	Tubby_N	TULP2 TULP3	1.46e-04	3	131	2	IPR005398
Domain	RSN1_TM	TMEM63C TMEM63A	1.46e-04	3	131	2	PF13967
Domain	Tub_N	TULP2 TULP3	1.46e-04	3	131	2	PF16322
Domain	Reeler_dom	FRRS1 SPON1	1.46e-04	3	131	2	IPR002861
Domain	PHM7_cyt	TMEM63C TMEM63A	1.46e-04	3	131	2	PF14703
Domain	RSN1_7TM	TMEM63C TMEM63A	1.46e-04	3	131	2	PF02714
Domain	Csc1_N	TMEM63C TMEM63A	1.46e-04	3	131	2	IPR032880
Domain	Reeler	FRRS1 SPON1	1.46e-04	3	131	2	PF02014
Domain	Cadherin	PCDHGC5 PCDHGA2 CLSTN2 FREM3 PCDHGA12 PCDHB1	1.84e-04	118	131	6	IPR002126
Domain	Cadherin_C	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	2.10e-04	42	131	4	IPR032455
Domain	Cadherin_C_2	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	2.10e-04	42	131	4	PF16492
Domain	Ig-like_dom	CHL1 HLA-DMB HEPACAM2 IL18R1 IGLL5 HEPACAM FCRL3 CSF3R PTPRK ADGRF5 KAZALD1 FCRL4	2.22e-04	503	131	12	IPR007110
Domain	Rib_L2_dom2	CUL9 CUL7 HERC2	2.55e-04	18	131	3	IPR014722
Domain	-	CUL9 CUL7 HERC2	2.55e-04	18	131	3	2.30.30.30
Domain	TUB_2	TULP2 TULP3	2.90e-04	4	131	2	PS01201
Domain	TUB_1	TULP2 TULP3	2.90e-04	4	131	2	PS01200
Domain	Tubby_C_CS	TULP2 TULP3	2.90e-04	4	131	2	IPR018066
Domain	G8_domain	PKHD1L1 PKHD1	2.90e-04	4	131	2	IPR019316
Domain	G8	PKHD1L1 PKHD1	2.90e-04	4	131	2	PS51484
Domain	G8	PKHD1L1 PKHD1	2.90e-04	4	131	2	SM01225
Domain	G8	PKHD1L1 PKHD1	2.90e-04	4	131	2	PF10162
Domain	FN3	CHL1 KIAA0319L PTPRG CSF3R PTPRK RIMBP2 EPHA3	3.32e-04	185	131	7	SM00060
Domain	Tub	TULP2 TULP3	4.82e-04	5	131	2	PF01167
Domain	-	TULP2 TULP3	4.82e-04	5	131	2	3.20.90.10
Domain	FN3_dom	CHL1 KIAA0319L PTPRG CSF3R PTPRK RIMBP2 EPHA3	6.88e-04	209	131	7	IPR003961
Domain	IG_LIKE	CHL1 HLA-DMB HEPACAM2 IL18R1 IGLL5 HEPACAM FCRL3 PTPRK ADGRF5 KAZALD1 FCRL4	6.90e-04	491	131	11	PS50835
Domain	Tubby_C-like	TULP2 TULP3	7.19e-04	6	131	2	IPR025659
Domain	PbH1	PKHD1L1 PKHD1	7.19e-04	6	131	2	SM00710
Domain	Tubby_C	TULP2 TULP3	7.19e-04	6	131	2	IPR000007
Domain	PbH1	PKHD1L1 PKHD1	7.19e-04	6	131	2	IPR006626
Domain	fn3	CHL1 PTPRG CSF3R PTPRK RIMBP2 EPHA3	9.94e-04	162	131	6	PF00041
Domain	Cadherin_2	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	1.12e-03	65	131	4	PF08266
Domain	Cadherin_N	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	1.12e-03	65	131	4	IPR013164
Domain	CADHERIN_1	PCDHGC5 PCDHGA2 CLSTN2 PCDHGA12 PCDHB1	1.21e-03	113	131	5	PS00232
Domain	Cadherin	PCDHGC5 PCDHGA2 CLSTN2 PCDHGA12 PCDHB1	1.21e-03	113	131	5	PF00028
Domain	CADHERIN_2	PCDHGC5 PCDHGA2 CLSTN2 PCDHGA12 PCDHB1	1.25e-03	114	131	5	PS50268
Domain	-	PCDHGC5 PCDHGA2 CLSTN2 PCDHGA12 PCDHB1	1.25e-03	114	131	5	2.60.40.60
Domain	CA	PCDHGC5 PCDHGA2 CLSTN2 PCDHGA12 PCDHB1	1.30e-03	115	131	5	SM00112
Domain	Cullin_neddylation_domain	CUL9 CUL7	1.33e-03	8	131	2	IPR019559
Domain	Pectin_lyase_fold/virulence	PKHD1L1 PKHD1	1.33e-03	8	131	2	IPR011050
Domain	Cullin_Nedd8	CUL9 CUL7	1.33e-03	8	131	2	PF10557
Domain	Cullin_Nedd8	CUL9 CUL7	1.33e-03	8	131	2	SM00884
Domain	Cadherin-like	PCDHGC5 PCDHGA2 CLSTN2 PCDHGA12 PCDHB1	1.35e-03	116	131	5	IPR015919
Domain	IGc2	CHL1 HEPACAM2 HEPACAM FCRL3 ADGRF5 KAZALD1 FCRL4	1.36e-03	235	131	7	SM00408
Domain	Ig_sub2	CHL1 HEPACAM2 HEPACAM FCRL3 ADGRF5 KAZALD1 FCRL4	1.36e-03	235	131	7	IPR003598
Domain	Cullin_homology	CUL9 CUL7	1.70e-03	9	131	2	IPR016158
Domain	PKD/Chitinase_dom	KIAA0319L SORCS2	1.70e-03	9	131	2	IPR022409
Domain	PKD	KIAA0319L SORCS2	1.70e-03	9	131	2	SM00089
Domain	Cullin	CUL9 CUL7	2.12e-03	10	131	2	PF00888
Domain	CULLIN_2	CUL9 CUL7	2.12e-03	10	131	2	PS50069
Domain	Cullin_N	CUL9 CUL7	2.12e-03	10	131	2	IPR001373
Domain	CULLIN_1	CUL9 CUL7	2.12e-03	10	131	2	PS01256
Domain	Cadherin_tail	PCDHGC5 PCDHGA2 PCDHGA12	2.20e-03	37	131	3	PF15974
Domain	Cadherin_CBD	PCDHGC5 PCDHGA2 PCDHGA12	2.20e-03	37	131	3	IPR031904
Domain	Ig_I-set	CHL1 HEPACAM2 HEPACAM PTPRK ADGRF5 KAZALD1	2.24e-03	190	131	6	IPR013098
Domain	I-set	CHL1 HEPACAM2 HEPACAM PTPRK ADGRF5 KAZALD1	2.24e-03	190	131	6	PF07679
Domain	ig	CHL1 HLA-DMB FCRL3 PTPRK ADGRF5 FCRL4	2.24e-03	190	131	6	PF00047
Domain	Immunoglobulin	CHL1 HLA-DMB FCRL3 PTPRK ADGRF5 FCRL4	2.24e-03	190	131	6	IPR013151
Domain	PKD	KIAA0319L SORCS2	2.58e-03	11	131	2	PS50093
Domain	PKD_dom	KIAA0319L SORCS2	2.58e-03	11	131	2	IPR000601
Domain	-	KIAA0319L SORCS2	2.58e-03	11	131	2	2.60.40.670
Domain	FN3	CHL1 PTPRG CSF3R PTPRK RIMBP2 EPHA3	2.82e-03	199	131	6	PS50853
Domain	IG	CHL1 HEPACAM2 IL18R1 HEPACAM FCRL3 PTPRK ADGRF5 KAZALD1 FCRL4	2.90e-03	421	131	9	SM00409
Domain	Ig_sub	CHL1 HEPACAM2 IL18R1 HEPACAM FCRL3 PTPRK ADGRF5 KAZALD1 FCRL4	2.90e-03	421	131	9	IPR003599
Domain	ARM-like	MROH5 ARFGEF2 CUL9 CUL7 IPO13 AP4B1 TARBP1	2.98e-03	270	131	7	IPR011989
Domain	Ldl_recept_b	LRP1B LRP1	4.20e-03	14	131	2	PF00058
Domain	LDLRB	LRP1B LRP1	4.20e-03	14	131	2	PS51120
Domain	-	MROH5 ARFGEF2 CUL9 CUL7 IPO13 AP4B1	4.81e-03	222	131	6	1.25.10.10
Domain	LY	LRP1B LRP1	4.83e-03	15	131	2	SM00135
Domain	LDLR_classB_rpt	LRP1B LRP1	4.83e-03	15	131	2	IPR000033
Domain	Growth_fac_rcpt_	LAMA3 LRP1B LRP1 KAZALD1 EPHA3	4.88e-03	156	131	5	IPR009030
Domain	MAM_1	MEP1B PTPRK	5.49e-03	16	131	2	PS00740
Domain	Nicotinic_acetylcholine_rcpt	CHRNA1 CHRNA2	5.49e-03	16	131	2	IPR002394
Domain	Sulfatase_CS	ARSJ ARSD	5.49e-03	16	131	2	IPR024607
Domain	SULFATASE_1	ARSJ ARSD	6.20e-03	17	131	2	PS00523
Domain	Cyclin_C-dom	CCNA2 CCNB1	6.20e-03	17	131	2	IPR004367
Domain	MAM	MEP1B PTPRK	6.20e-03	17	131	2	SM00137
Domain	Cyclin_C	CCNA2 CCNB1	6.20e-03	17	131	2	PF02984
Domain	SULFATASE_2	ARSJ ARSD	6.20e-03	17	131	2	PS00149
Domain	Cyclin_C	CCNA2 CCNB1	6.20e-03	17	131	2	SM01332
Domain	MAM	MEP1B PTPRK	6.94e-03	18	131	2	PF00629
Domain	Sulfatase	ARSJ ARSD	6.94e-03	18	131	2	PF00884
Domain	MAM_dom	MEP1B PTPRK	6.94e-03	18	131	2	IPR000998
Domain	MAM_2	MEP1B PTPRK	6.94e-03	18	131	2	PS50060
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-18 ERVK-19	1.33e-09	5	142	4	12629516
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-11	5.24e-09	94	142	8	21542922
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-18 ERVK-19	6.66e-08	3	142	3	10516026
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	2.66e-07	4	142	3	10469592
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10 ERVK-19	2.66e-07	4	142	3	7983737
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-18 ERVK-25 ERVK-11	7.80e-07	18	142	4	18664271
Pubmed	Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.	TUBG2 TULP3 SMO	3.68e-06	8	142	3	27727273
Pubmed	How APC/C-Cdc20 changes its substrate specificity in mitosis.	CCNA2 CCNB1 ANAPC10	5.50e-06	9	142	3	21336306
Pubmed	RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain.	GLE1 HERC2 ANKS1A	7.83e-06	10	142	3	29097665
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	RIMBP2 UNC13C RIMS1	1.07e-05	11	142	3	34767769
Pubmed	Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.	APOB IGLL5 CHRNA1 GHRHR STRADB ARNT	1.09e-05	121	142	6	8827514
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19	1.43e-05	12	142	3	14557543
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1B LRP1	1.66e-05	2	142	2	15963947
Pubmed	Cytoplasmic accumulation of cyclin B1 in human cells: association with a detergent-resistant compartment and with the centrosome.	CCNA2 CCNB1	1.66e-05	2	142	2	1387877
Pubmed	Cell-specific expression of tubby gene family members (tub, Tulp1,2, and 3) in the retina.	TULP2 TULP3	1.66e-05	2	142	2	10509669
Pubmed	Cyclin A and cyclin B1 overexpression in differentiated thyroid carcinoma.	CCNA2 CCNB1	1.66e-05	2	142	2	21264543
Pubmed	Raloxifene increases proliferation of human endothelial cells in association with increased gene expression of cyclins A and B1.	CCNA2 CCNB1	1.66e-05	2	142	2	17445807
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.66e-05	2	142	2	9060628
Pubmed	Expression and prognostic significance of cyclin B1 and cyclin A in non-small cell lung cancer.	CCNA2 CCNB1	1.66e-05	2	142	2	19614764
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.66e-05	2	142	2	9460924
Pubmed	Patterns of cyclin A and B1 immunostaining in papillary thyroid carcinoma.	CCNA2 CCNB1	1.66e-05	2	142	2	26706989
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	1.66e-05	2	142	2	11672541
Pubmed	MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C.	CCNA2 CCNB1 ANAPC10	1.85e-05	13	142	3	25750436
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RBM11 TUBG2 UBR4 KIAA0319L ARFGEF2 CUL9 MDH1 SKIL LRP1B FRY PTPRK MKLN1 LRP1 FMN2 DNAI7 HERC2 TARBP1	2.08e-05	1285	142	17	35914814
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	VPS13C KIAA0319L ARFGEF2 SLC12A2 PLEKHM2 GLE1 PI4KA FMN2 ATG9A RIC1	4.51e-05	504	142	10	34432599
Pubmed	Co-expression of mouse TMEM63A, TMEM63B and TMEM63C confers hyperosmolarity activated ion currents in HEK293 cells.	TMEM63C TMEM63A	4.95e-05	3	142	2	27045885
Pubmed	L1 and CHL1 Cooperate in Thalamocortical Axon Targeting.	CHL1 EPHA3	4.95e-05	3	142	2	20576928
Pubmed	Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.	CUL9 CUL7	4.95e-05	3	142	2	15964813
Pubmed	Expression and prognostic value of CDK1, CCNA2, and CCNB1 gene clusters in human breast cancer.	CCNA2 CCNB1	4.95e-05	3	142	2	33896262
Pubmed	The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.	CUL9 CUL7	4.95e-05	3	142	2	17298945
Pubmed	Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.	CACNA1D RIMS1	4.95e-05	3	142	2	26034270
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-11	4.95e-05	3	142	2	9971820
Pubmed	Molecular cloning and characterization of the mouse and human TUSP gene, a novel member of the tubby superfamily.	TULP2 TULP3	4.95e-05	3	142	2	11595174
Pubmed	Targeted resequencing reveals genetic risks in patients with sporadic idiopathic pulmonary fibrosis.	LAMA3 CSF3R	4.95e-05	3	142	2	29920840
Pubmed	The roles of cyclin A2, B1, and B2 in early and late mitotic events.	CCNA2 CCNB1	4.95e-05	3	142	2	20660152
Pubmed	A novel p53-binding domain in CUL7.	CUL9 CUL7	4.95e-05	3	142	2	16875676
Pubmed	Mutational and expression analysis of CDK1, cyclinA2 and cyclinB1 in epilepsy-associated glioneuronal lesions.	CCNA2 CCNB1	4.95e-05	3	142	2	17359356
Pubmed	Cell cycle in mouse development.	CCNA2 CCNB1	4.95e-05	3	142	2	15838522
Pubmed	Function of cyclins in regulating the mitotic and meiotic cell cycles in male germ cells.	CCNA2 CCNB1	4.95e-05	3	142	2	19001847
Pubmed	ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.	LRP1 ANKS1A	4.95e-05	3	142	2	38123547
Pubmed	Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.	CUL9 CUL7	4.95e-05	3	142	2	17229476
Pubmed	Cell cycle marker expression in benign and malignant intraductal papillary lesions of the breast.	CCNA2 CCNB1	4.95e-05	3	142	2	25501285
Pubmed	LRP1B, BRD2 and CACNA1D: new candidate genes in fetal metabolic programming of newborns exposed to maternal hyperglycemia.	CACNA1D LRP1B	4.95e-05	3	142	2	26586120
Pubmed	Molecular cloning, expression and regulation of the avian tubby-like protein 1 (tulp1) gene.	TULP2 TULP3	4.95e-05	3	142	2	11483369
Pubmed	A protein interaction landscape of breast cancer.	EED UBR4 CUL9 CUL7 CCNA2 CCNB1 STRADB COPS8 PI4KA LRP1 SMARCB1	6.26e-05	634	142	11	34591612
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CHL1 HLA-DMB APOB ITGA2B PTPRG LRP1 ADGRF5	9.44e-05	257	142	7	16335952
Pubmed	The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.	CUL7 CCNA2 CCNB1	9.69e-05	22	142	3	36877136
Pubmed	Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism.	IGKV6D-21 IGKV6-21	9.88e-05	4	142	2	6264318
Pubmed	Examination of the nicotine dependence (NICSNP) consortium findings in the Iowa adoption studies population.	CHRNA1 CHRNA2	9.88e-05	4	142	2	19307444
Pubmed	GRK2 negatively regulates IGF-1R signaling pathway and cyclins' expression in HepG2 cells.	CCNA2 CCNB1	9.88e-05	4	142	2	23460259
Pubmed	Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice.	APOB LRP1	9.88e-05	4	142	2	9788969
Pubmed	Cyclin B and cyclin A confer different substrate recognition properties on CDK2.	CCNA2 CCNB1	9.88e-05	4	142	2	17495531
Pubmed	The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer.	CCNA2 CCNB1	9.88e-05	4	142	2	24324728
Pubmed	Evaluating the effect of nicotinic cholinergic receptor genes on the risk of nonsyndromic cleft lip with or without cleft palate.	CHRNA1 CHRNA2	9.88e-05	4	142	2	29688589
Pubmed	NF-Y binds to both G1- and G2-specific cyclin promoters; a possible role in linking CDK2/Cyclin A to CDK1/Cyclin B.	CCNA2 CCNB1	9.88e-05	4	142	2	21871181
Pubmed	ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.	TUBG2 CILK1 SMO	1.27e-04	24	142	3	24797473
Pubmed	The protein interaction landscape of the human CMGC kinase group.	PSMA7 CILK1 DIDO1 CUL7 CCNA2 CCNB1 FRY PRPF4 CIAO1 HERC2 EPHA3	1.40e-04	695	142	11	23602568
Pubmed	Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.	TULP3 PKHD1 SMO	1.43e-04	25	142	3	28154160
Pubmed	Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.	RIMBP2 UNC13C RIMS1	1.62e-04	26	142	3	17124501
Pubmed	Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.	FCRL3 FCRL4	1.64e-04	5	142	2	18704934
Pubmed	An essential phosphorylation-site domain of human cdc25C interacts with both 14-3-3 and cyclins.	CCNA2 CCNB1	1.64e-04	5	142	2	10864927
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	1.64e-04	5	142	2	11401426
Pubmed	Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15.	CCNA2 CCNB1	1.64e-04	5	142	2	8475101
Pubmed	A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release.	RIMBP2 RIMS1	1.64e-04	5	142	2	32755572
Pubmed	PARC and CUL7 form atypical cullin RING ligase complexes.	CUL9 CUL7	1.64e-04	5	142	2	17332328
Pubmed	Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling.	CCNA2 CCNB1	1.64e-04	5	142	2	21540187
Pubmed	Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development.	CCNB1 SMO	1.64e-04	5	142	2	17850284
Pubmed	Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia.	FCRL3 FCRL4	1.64e-04	5	142	2	16849395
Pubmed	IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells.	FCRL3 FCRL4	1.64e-04	5	142	2	11929751
Pubmed	Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.	CCNA2 CCNB1	1.64e-04	5	142	2	11444800
Pubmed	Biallelic variants in TSPOAP1, encoding the active-zone protein RIMBP1, cause autosomal recessive dystonia.	RIMBP2 RIMS1	1.64e-04	5	142	2	33539324
Pubmed	An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.	UNC13C RIMS1	1.64e-04	5	142	2	34706221
Pubmed	CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.	CUL9 CUL7	1.64e-04	5	142	2	24793696
Pubmed	Identification of a family of Fc receptor homologs with preferential B cell expression.	FCRL3 FCRL4	1.64e-04	5	142	2	11493702
Pubmed	The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.	PKHD1L1 PKHD1	1.64e-04	5	142	2	20048263
Pubmed	A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution.	PKHD1 SMO	1.64e-04	5	142	2	20558667
Pubmed	Phosphorylation of Cdc25B3 Ser169 regulates 14-3-3 binding to Ser151 and Cdc25B activity.	CCNA2 CCNB1	1.64e-04	5	142	2	21558810
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	1.77e-04	68	142	4	11230163
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ARSJ UBR4 AOC2 KIAA0319L ARFGEF2 CUL9 DENND1A PLEKHM2 PI4KA KAZALD1 ATG9A HERC2 SOWAHB RIC1	1.82e-04	1105	142	14	35748872
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	2.21e-04	72	142	4	10380929
Pubmed	Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina.	CCNA2 CCNB1 SMO	2.25e-04	29	142	3	19474320
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	2.46e-04	74	142	4	10817752
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	UBR4 CUL9 CUL7 CIAO1 AGK HERC2	2.46e-04	212	142	6	33853758
Pubmed	Patterns of expression of cyclins A, B1, D, E and cdk 2 in preimplantation mouse embryos.	CCNA2 CCNB1	2.46e-04	6	142	2	15214576
Pubmed	G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.	CCNA2 CCNB1	2.46e-04	6	142	2	8463339
Pubmed	Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop.	CCNA2 CCNB1	2.46e-04	6	142	2	11113184
Pubmed	A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor suppressor proteins.	CCNA2 CCNB1	2.46e-04	6	142	2	10581175
Pubmed	Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1.	CCNA2 CCNB1	2.46e-04	6	142	2	24623419
Pubmed	Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27.	CCNA2 CCNB1	2.46e-04	6	142	2	31822694
Pubmed	Characterization of the in vitro reconstituted cyclin A or B1-dependent cdk2 and cdc2 kinase activities.	CCNA2 CCNB1	2.46e-04	6	142	2	8397207
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-19	2.46e-04	6	142	2	15063128
Pubmed	How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.	RIMBP2 RIMS1	2.46e-04	6	142	2	27537484
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	2.86e-04	77	142	4	10835267
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	UBR4 CUL9 CUL7 SLC12A2 PI4KA KLHL12 HERC2	3.15e-04	313	142	7	38270169
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	3.31e-04	80	142	4	10716726
Pubmed	APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase.	CCNA2 CCNB1	3.43e-04	7	142	2	17679094
Pubmed	The cyclin box and C-terminus of cyclins A and E specify CDK activation and substrate specificity.	CCNA2 CCNB1	3.43e-04	7	142	2	9053846
Pubmed	Differential expression of individual gamma-protocadherins during mouse brain development.	PCDHGC5 PCDHGA12	3.43e-04	7	142	2	15964765
Pubmed	Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C.	CCNA2 CCNB1	3.43e-04	7	142	2	31455778
Pubmed	Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency.	PKHD1 SMO	3.43e-04	7	142	2	34093381
GeneFamily	Immunoglobulin like domain containing	CHL1 HEPACAM2 IL18R1 HEPACAM FCRL3 PTPRK ADGRF5 FCRL4	7.41e-06	193	94	8	594
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ITGA2B SLC12A2 SPZ1 SMARCB1 RIMBP2 DNAI7 MYO16	4.41e-05	181	94	7	694
GeneFamily	Clustered protocadherins	PCDHGC5 PCDHGA2 PCDHGA12 PCDHB1	3.43e-04	64	94	4	20
GeneFamily	Cullins	CUL9 CUL7	7.34e-04	8	94	2	1032
GeneFamily	Fibronectin type III domain containing	CHL1 PTPRG CSF3R PTPRK EPHA3	1.49e-03	160	94	5	555
GeneFamily	Low density lipoprotein receptors	LRP1B LRP1	2.01e-03	13	94	2	634
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA1 CHRNA2	3.06e-03	16	94	2	173
GeneFamily	Sulfatases	ARSJ ARSD	3.88e-03	18	94	2	410
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	IL15RA ITGA2B IL18R1 FCRL3 CSF3R LRP1 FCRL4	4.46e-03	394	94	7	471
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRG PTPRK	5.27e-03	21	94	2	813
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA APOB LRP1B PKHD1L1 PKHD1 UNC13C MYO16	1.38e-06	184	133	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA APOB LRP1B PKHD1L1 PKHD1 UNC13C MYO16	1.38e-06	184	133	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA APOB LRP1B PKHD1L1 PKHD1 UNC13C MYO16	1.38e-06	184	133	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C LAMA3 LRP1B CSF3R FCN1 PKHD1 LRP1	1.48e-06	186	133	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 OTOA IGLL5 PTPRK SORCS2 RIC1	3.72e-06	138	133	6	76be06136c83c167cedece7515228ed4d29dd1f0
ToppCell	390C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NXPE4 PKHD1L1 IGLL5 FRRS1 RIMS1 IGKV6-21	1.07e-05	166	133	6	4ba3711a02d3695b27f7cefd7c60e3be009f5bef
ToppCell	390C-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NXPE4 PKHD1L1 IGLL5 FRRS1 RIMS1 IGKV6-21	1.07e-05	166	133	6	35f6ae2664935dda0d883b32a050ced843204f2d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 LRP1B SORCS2 UNC13C EPHA3	1.65e-05	179	133	6	b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PKHD1L1 IGLL5 FCRL3 PTPRK FCRL4 IGKV6-21	1.75e-05	181	133	6	700adfb41e4e377530f0dd31be89e12f109f3469
ToppCell	Control-Lymphocyte-B-B_intermediate\|Control / Disease, Lineage and Cell Type	PKHD1L1 IGLL5 FCRL3 PTPRK SMARCB1 FCRL4	2.11e-05	187	133	6	90c9b1a51539838323325f563be4adf5fdf1b38f
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRDE2 NXPE4 PCYOX1L FRY SMO KAZALD1	2.11e-05	187	133	6	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRDE2 NXPE4 PCYOX1L FRY SMO KAZALD1	2.11e-05	187	133	6	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CHL1 CACNA1D SPON1 SORCS2 LRP1 MYO16	2.30e-05	190	133	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMA3 CSF3R PTPRK SORCS2 PKHD1 ADGRF5	2.44e-05	192	133	6	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CHL1 CACNA1D SPON1 LRP1 MYO16 EPHA3	2.59e-05	194	133	6	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA3 PTPRG CSF3R PTPRK SORCS2 ADGRF5	2.59e-05	194	133	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PSMA7 MDH1 CHRNA1 CCNA2 CCNB1 GPR151	2.67e-05	195	133	6	5556f280a5b42bda6e47b9d308946b7d5f4fa656
ToppCell	control-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HLA-DMB PKHD1L1 IGLL5 FCRL3 PTPRK SMARCB1	2.67e-05	195	133	6	ddbc924b1a08685da0ed0755856178bae99a75b9
ToppCell	proximal-Hematologic-Interstitial_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	OTOA RC3H2 IGLL5 DENND1A FRRS1 PLEKHM2	2.74e-05	196	133	6	b6a858c43fef42cd724d56c8283e954bcb546106
ToppCell	proximal-3-Hematologic-Interstitial_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	OTOA RC3H2 IGLL5 DENND1A FRRS1 PLEKHM2	2.74e-05	196	133	6	d8c9cb86233470c3044865ad05ea202e294d80bf
ToppCell	proximal-Hematologic-Interstitial_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	OTOA RC3H2 IGLL5 DENND1A FRRS1 PLEKHM2	2.74e-05	196	133	6	9d4d8ffe9d30de7d1dc33d261bc2aaf4189ad86c
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	RC3H2 HLA-DMB ARFGEF2 DIDO1 PI4KA TARBP1	2.74e-05	196	133	6	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HLA-DMB CYP27A1 CSF3R FCN1 LRP1 RIMS1	2.90e-05	198	133	6	a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1D PGM2L1 FRY RIMBP2 RIMS1 TARBP1	2.90e-05	198	133	6	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TMEM63C ITGA2B PKHD1L1 CCNB1 STRADB SLC13A4	2.99e-05	199	133	6	f894c88ecc7fd0edca28587801fa59352d10f750
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CHL1 CACNA1D SPON1 LRP1 SMO MYO16	2.99e-05	199	133	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Sepsis-ICU-SEP-Lymphocyte-B-B_intermediate\|ICU-SEP / Disease, condition lineage and cell class	HLA-DMB PKHD1L1 FCRL3 SPON1 SMARCB1 FCRL4	2.99e-05	199	133	6	160b0f9687a996c4fea2a1a66f225af386483951
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TMEM63C ITGA2B PKHD1L1 CCNB1 STRADB SLC13A4	2.99e-05	199	133	6	2b754670fe77c2301afcdcfc73a1e52cc0cd1de3
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FRY SLC12A2 PTPRG PTPRK ADGRF5 EPHA3	3.07e-05	200	133	6	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FRY SLC12A2 PTPRG PTPRK ADGRF5 EPHA3	3.07e-05	200	133	6	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FRY SLC12A2 PTPRG PTPRK ADGRF5 EPHA3	3.07e-05	200	133	6	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ARSJ CLSTN2 LRP1B PTPRK SORCS2 EPHA3	3.07e-05	200	133	6	1a3d29a580d1b405a74869a1da3e818c581fc559
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FRY SLC12A2 PTPRG PTPRK ADGRF5 EPHA3	3.07e-05	200	133	6	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E---L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ARSJ CLSTN2 LRP1B PTPRK SORCS2 EPHA3	3.07e-05	200	133	6	6f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ARSJ CLSTN2 LRP1B PTPRK SORCS2 EPHA3	3.07e-05	200	133	6	86705dfc05b3e1576543b93883c88fb55b742855
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ARSJ CLSTN2 LRP1B PTPRK SORCS2 EPHA3	3.07e-05	200	133	6	db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FRY SLC12A2 PTPRG PTPRK ADGRF5 EPHA3	3.07e-05	200	133	6	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FRY SLC12A2 PTPRG PTPRK ADGRF5 EPHA3	3.07e-05	200	133	6	7136936d05ab344a560cf159684c881063b5430d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	CHL1 HEPACAM2 SLC13A4 RIMBP2 EPHA3	3.84e-05	126	133	5	ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCell	Control-B_activate-7\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CHL1 OTOA CLSTN2 SORCS2 FCRL4	4.46e-05	130	133	5	d3343c19d61928f18e7d707eda5dec6e0fd2a9a2
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM3 CSF3R UNC13C KLHL12 RIMS1	9.94e-05	154	133	5	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM3 CSF3R UNC13C KLHL12 RIMS1	9.94e-05	154	133	5	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	390C-Lymphocytic-Plasma_cell-\|390C / Donor, Lineage, Cell class and subclass (all cells)	NXPE4 PKHD1L1 IGLL5 FCRL4 IGKV6-21	1.06e-04	156	133	5	4f92ca30755430db44402afc603d1ecd8bfc3617
ToppCell	390C-Lymphocytic-Plasma_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	NXPE4 PKHD1L1 IGLL5 FCRL4 IGKV6-21	1.06e-04	156	133	5	0de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B PKHD1L1 PTPRG PKHD1 RIMBP2	1.19e-04	160	133	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B PKHD1L1 PTPRG PKHD1 RIMBP2	1.19e-04	160	133	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AOC2 OGG1 CCNA2 PCYOX1L ADGRF5	1.30e-04	163	133	5	3efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RBM11 CHRNA2 SLC12A2 UNC13C TARBP1	1.34e-04	164	133	5	d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA ITGA2B IL18R1 TULP3 ADGRF5	1.41e-04	166	133	5	c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA ITGA2B IL18R1 TULP3 ADGRF5	1.41e-04	166	133	5	0975fc165bcc7e85f053d9d0244fffe407c23571
ToppCell	(0)_Myeloid-(00)_Monocyte-(000)_CD14+_Monocyte\|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)	HLA-DMB CYP27A1 CSF3R FCN1 LRP1	1.45e-04	167	133	5	7d9fd6a7a45c2aa0d5f2e3960ca4c97ee8836ba5
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARSJ HEPACAM2 RIMBP2 ADGRF5 UNC13C	1.49e-04	168	133	5	6a233045638cb83dab64789b996b7598c325001e
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PKHD1L1 IGLL5 FCRL3 PTPRK FCRL4	1.54e-04	169	133	5	307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell	Ionocyte\|World / Class top	CACNA1D HEPACAM2 SLC12A2 FMN2 ADGRF5	1.58e-04	170	133	5	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-5\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DMB SLC6A16 IGLL5 STRADB AP4B1	1.62e-04	171	133	5	23b3120706bb9c20b9214fe3760c6d7a84f1e749
ToppCell	ICU-SEP-Lymphocyte-B-B_intermediate\|ICU-SEP / Disease, Lineage and Cell Type	HLA-DMB PKHD1L1 FCRL3 SMARCB1 FCRL4	1.62e-04	171	133	5	2e44bf6f3d90193e7cadcac48bb852bd632a81bc
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 SORCS2 UNC13C EPHA3	1.67e-04	172	133	5	92e76cbf4807704790f42cf2507e92f85cd3bc92
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DMB HEPACAM2 IL18R1 UNC13C RIMS1	1.67e-04	172	133	5	3ffe721f62c0d20c1d765ecb15ed4e1aa88099f7
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DMB HEPACAM2 IL18R1 UNC13C RIMS1	1.67e-04	172	133	5	2bbe3f601a56577d200aa7ba7031f7c19b988cc1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IL18R1 PKHD1L1 CHRNA1 ADGRF5 ANKS1A	1.71e-04	173	133	5	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 SORCS2 UNC13C EPHA3	1.71e-04	173	133	5	5aa4d45a01d2d09eff8b4deb32bd91ab2471210a
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HEPACAM2 KHDRBS3 PTPRG ADGRF5 UNC13C	1.76e-04	174	133	5	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HEPACAM2 KHDRBS3 PTPRG ADGRF5 UNC13C	1.76e-04	174	133	5	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1D CYP27A1 SLC13A4 SPON1 LRP1	1.76e-04	174	133	5	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	HEPACAM2 KHDRBS3 PTPRG ADGRF5 UNC13C	1.76e-04	174	133	5	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HEPACAM2 KHDRBS3 PTPRG ADGRF5 UNC13C	1.76e-04	174	133	5	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-B_plasma-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CAPN14 PKHD1L1 IGLL5 PTPRG SMARCB1	1.76e-04	174	133	5	bdbaf805a94b2f5a0065933dab6bf84e3cabd525
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 CCNA2 CCNB1 PTPRG PCDHGA12	1.81e-04	175	133	5	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 CCNA2 CCNB1 PTPRG PCDHGA12	1.81e-04	175	133	5	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	NDST4 APOB HEPACAM2 ASB5 ADGRF5	1.81e-04	175	133	5	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 CCNA2 CCNB1 PTPRG PCDHGA12	1.81e-04	175	133	5	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 CCNA2 CCNB1 PTPRG PCDHGA12	1.81e-04	175	133	5	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 SORCS2 UNC13C EPHA3	1.91e-04	177	133	5	7e799333307448c6a94d1f33dbc59c543336f45e
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1D HLA-DMB TUBG2 PKHD1L1 PTPRK	1.91e-04	177	133	5	3535575686c9700ab72700aae6f2070ebbb50044
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 HLA-DMB PKHD1L1 PTPRK FCRL4	1.96e-04	178	133	5	be1d991c5a0a5be22f14f57d34ee1330f1a12963
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 SORCS2 UNC13C EPHA3	1.96e-04	178	133	5	a48739a588f361b4bc69405d7e256c11f61cf43c
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NXPE4 CUL7 TULP3 ARNT ADGRF5	2.01e-04	179	133	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ARSJ SPON1 LRP1 MYO16	2.06e-04	180	133	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 CHRNA1 SORCS2 EPHA3	2.06e-04	180	133	5	8923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TUBG2 CYP27A1 KHDRBS3 GLE1 KLHL12	2.06e-04	180	133	5	d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ARSJ SPON1 LRP1 MYO16	2.06e-04	180	133	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ARSJ SPON1 LRP1 MYO16	2.11e-04	181	133	5	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	TMEM63C HEPACAM2 FMN2 RIMBP2 RIMS1	2.17e-04	182	133	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARSJ HEPACAM2 RIMBP2 ADGRF5 UNC13C	2.22e-04	183	133	5	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA3 CSF3R PTPRK SORCS2 ADGRF5	2.22e-04	183	133	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HLA-DMB PKHD1L1 IGLL5 FCRL3 PTPRK	2.22e-04	183	133	5	f4f453692da77cef666cc281c4883c9c6b279fd4
ToppCell	Mild-Lymphoid-B\|Mild / Condition, Lineage, Cell class and cell subclass	PKHD1L1 FCRL3 PTPRK FCRL4 IGKV6-21	2.22e-04	183	133	5	9b64d2d143525e6f48a191facfd101462ff36324
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HLA-DMB PKHD1L1 IGLL5 FCRL3 PTPRK	2.22e-04	183	133	5	6086a862ab35bc683af44c03ee14cbb08ab99945
ToppCell	Mild_COVID-19-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PKHD1L1 IGLL5 FCRL3 PTPRK FCRL4	2.22e-04	183	133	5	dea119e2988e954475f557f0bbe12556a83e81a4
ToppCell	Mild-Lymphoid-B-\|Mild / Condition, Lineage, Cell class and cell subclass	PKHD1L1 FCRL3 PTPRK FCRL4 IGKV6-21	2.22e-04	183	133	5	b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CLSTN2 KIAA1586 PTPRG PCDHGA12 EPHA3	2.28e-04	184	133	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 LRP1B SORCS2 EPHA3	2.28e-04	184	133	5	9cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PKHD1L1 FCRL3 PTPRK FCRL4 IGKV6-21	2.28e-04	184	133	5	3f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PKHD1L1 FCRL3 PTPRK FCRL4 IGKV6-21	2.28e-04	184	133	5	64bede8db709fd32f40c03265b96f0b12155bb8a
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA3 FRY KHDRBS3 ASB5 ADGRF5	2.34e-04	185	133	5	35d39a1d04c871edcfb749653538dc5fd0054281
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PKHD1L1 FCRL3 PTPRK FCRL4 IGKV6-21	2.34e-04	185	133	5	609080adb2cfb105bb7b8efb617553833299f371
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D KIAA0319L PTPRK PKHD1 LRP1	2.34e-04	185	133	5	1d874608aa2062024323512f68889219471b2f00
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARSJ CLSTN2 SORCS2 UNC13C EPHA3	2.34e-04	185	133	5	a1b2525da018abe458908cab7268bd403ee98d92
ToppCell	control-B_memory\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HLA-DMB PKHD1L1 IGLL5 CHRNA1 SMARCB1	2.40e-04	186	133	5	93066e9a043036dbdadcbcc04fa6a7be7a562596
ToppCell	BL-critical-LOC-Lymphoid-B_cell\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HLA-DMB PKHD1L1 IGLL5 FCRL3 FCRL4	2.40e-04	186	133	5	27d4c38b180e4ce2bf3e7c4ad3db3a2ffca05ca8
Disease	childhood onset asthma	ADAD1 HLA-DMB IL18R1 ARNT PTPRK GAL3ST3 MKLN1 LRP1 IP6K2	1.51e-05	334	127	9	MONDO_0005405
Disease	tea consumption measurement	TUBG2 CUL9 DENND1A ARNT PKHD1 EPHA3	2.08e-05	129	127	6	EFO_0010091
Disease	epilepsy (implicated_via_orthology)	CHL1 LRP1B SLC13A4 SLC12A2 LRP1 UNC13C	7.72e-05	163	127	6	DOID:1826 (implicated_via_orthology)
Disease	Fc receptor-like protein 4 measurement	FCRL3 FCRL4	1.10e-04	4	127	2	EFO_0801599
Disease	Fc receptor-like protein 3 measurement	FCRL3 FCRL4	1.10e-04	4	127	2	EFO_0008127
Disease	ficolin-2 measurement	NXPE4 FCN1	1.82e-04	5	127	2	EFO_0008135
Disease	atopic asthma	ADAD1 IL18R1 PTPRK GAL3ST3 LRP1 RIC1	2.29e-04	199	127	6	EFO_0010638
Disease	MASA syndrome (implicated_via_orthology)	CHL1 TRPM1	3.81e-04	7	127	2	DOID:0060246 (implicated_via_orthology)
Disease	Schizophrenia	CHL1 MDH1 IL18R1 CCNA2 CBLIF SLC12A2 ADSS2 PI4KA ERVK-8 LRP1 TRPM1 MYO16	4.42e-04	883	127	12	C0036341
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	CILK1 CUL7 OGG1 LRP1B FMN2	4.61e-04	148	127	5	C0279702
Disease	basal cell carcinoma (is_marker_for)	OGG1 SMO	5.06e-04	8	127	2	DOID:2513 (is_marker_for)
Disease	response to anticonvulsant	CLSTN2 COPS8 SORCS2 SOWAHB	5.06e-04	85	127	4	GO_0036277
Disease	left ventricular systolic function measurement	LRP1B SPON1 SMARCB1	9.06e-04	44	127	3	EFO_0008206
Disease	Huntington Disease, Late Onset	OGG1 IP6K2	1.18e-03	12	127	2	C0393574
Disease	Akinetic-Rigid Variant of Huntington Disease	OGG1 IP6K2	1.18e-03	12	127	2	C0751207
Disease	Juvenile Huntington Disease	OGG1 IP6K2	1.18e-03	12	127	2	C0751208
Disease	executive function measurement	ARFGEF2 CUL9 LRP1B PTPRK UNC13C RIMS1 IP6K2	1.25e-03	376	127	7	EFO_0009332
Disease	response to fenofibrate	IL15RA PSMA7 SPON1	1.32e-03	50	127	3	GO_1901557
Disease	gallbladder cancer (is_implicated_in)	APOB LRP1B	1.39e-03	13	127	2	DOID:3121 (is_implicated_in)
Disease	asthma	ADAD1 CLSTN2 LGSN IL18R1 LRP1B PTPRK COPS8 GAL3ST3 LRP1 UNC13C	1.55e-03	751	127	10	MONDO_0004979
Disease	Uveal Melanoma	LRP1B HERC2 TDP1	1.56e-03	53	127	3	EFO_1000616
Disease	lysophosphatidylcholine 15:0 measurement	LRP1B PKHD1	1.62e-03	14	127	2	EFO_0020941
Disease	amenorrhea, response to antineoplastic agent	APOB RIMS1	1.86e-03	15	127	2	EFO_0010269, GO_0097327
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA1 CHRNA2	2.12e-03	16	127	2	DOID:3635 (implicated_via_orthology)
Disease	Sarcomatoid Renal Cell Carcinoma	CUL7 OGG1 LRP1B FMN2	2.31e-03	128	127	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	CUL7 OGG1 LRP1B FMN2	2.31e-03	128	127	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	CUL7 OGG1 LRP1B FMN2	2.31e-03	128	127	4	C1266044
Disease	Papillary Renal Cell Carcinoma	CUL7 OGG1 LRP1B FMN2	2.31e-03	128	127	4	C1306837
Disease	Renal Cell Carcinoma	CUL7 OGG1 LRP1B FMN2	2.31e-03	128	127	4	C0007134
Disease	response to radiation, Urinary retention	LRP1B COPS8	2.40e-03	17	127	2	GO_0009314, HP_0000016
Disease	Huntington Disease	OGG1 IP6K2	2.40e-03	17	127	2	C0020179
Disease	type 2 diabetes mellitus (is_marker_for)	CACNA1D APOB OGG1 ARNT	2.88e-03	136	127	4	DOID:9352 (is_marker_for)
Disease	thrombin activatable fibrinolysis inhibitor activation peptide measurement	OTOA DENND1A	3.00e-03	19	127	2	EFO_0008582
Disease	stroke, major depressive disorder	DENND1A PTPRG	3.00e-03	19	127	2	EFO_0000712, MONDO_0002009
Disease	Meningioma	SMARCB1 SMO	3.00e-03	19	127	2	C0025286
Disease	severe acute respiratory syndrome, COVID-19	LRP1B ADSS2 SORCS2 MKLN1 RIMBP2 UNC13C TRPM1	3.29e-03	447	127	7	EFO_0000694, MONDO_0100096
Disease	Colorectal Carcinoma	CHL1 APOB CLSTN2 GHRHR ARNT FCN1 PKHD1 LRP1 EPHA3	3.42e-03	702	127	9	C0009402
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGC5 PCDHGA2 PCDHGA12	3.60e-03	71	127	3	EFO_0007878, EFO_0007979
Disease	respiratory system disease	ADAD1 IL18R1 PTPRK RIC1	3.62e-03	145	127	4	EFO_0000684
Disease	intellectual disability (implicated_via_orthology)	UBR4 NDST4 ITGA2B	4.20e-03	75	127	3	DOID:1059 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TALQVSWSQPETIYH	PTPRG	361	P23470
KWNPRNYSSGTHNIE	TMEM62	376	Q0P6H9
PLGTFSKYTWHITNI	C2orf42	426	Q9NWW7
QSEWFGSTLYDQVHP	ARNT	201	P27540
LKEWPQTHQASISYT	AGK	241	Q53H12
QKDSGSVWKVHYTTP	ARSD	471	P51689
TYQDHLWRSGNKSSP	EIF2D	171	P41214
YQWGGSHSNKKLLSS	AFTPH	716	Q6ULP2
HYWGEKLTLTPGNTL	FCRL4	61	Q96PJ5
PLYSGVHNWTSSDRI	BCORL1	6	Q5H9F3
EWSKDLYVNPNHQTS	ARFGEF2	576	Q9Y6D5
NTLVPVYGKAHWATI	AP4B1	561	Q9Y6B7
KLSPSYHWLESNVDA	CHRNA2	396	Q15822
LQQHGYGSWIVKSPC	ADAD1	556	Q96M93
SLPKLSSYSGWVVEH	GLE1	41	Q53GS7
PSWLDSLGLQDYVHS	ANKS1A	776	Q92625
KPWIETSYHGVITEN	CLSTN2	41	Q9H4D0
TPGLLSQEAAQKWTY	CAPN14	336	A8MX76
SPEQWSSLLYGDLAH	RC3H2	296	Q9HBD1
QWAQYHTQKAPLVSS	RC3H2	781	Q9HBD1
EAGPSSYKWTHQQPS	RBM11	181	P57052
DLEAGPSSYKWTHQQ	RBM11	221	P57052
PSSYKWTHQQPSDSD	RBM11	226	P57052
NAWLSYHLLKASEPG	PCDHGA2	601	Q9Y5H1
HVVQISSTYLESNWP	RIC1	481	Q4ADV7
HAWDPDIGKNSLQSY	PCDHGA12	156	O60330
DSGQNSWLSYHLLKA	PCDHB1	596	Q9Y5F3
TKVLLQYTGHITWTP	CHRNA1	126	P02708
SSIYHQNDIWTPTVT	AOC2	641	O75106
LGQYGLPQHWTAETT	OTOA	746	Q7RTW8
WYKSSGSQEHVELNP	IL18R1	56	Q13478
SHPYDTWNVTGQDVI	KAZALD1	176	Q96I82
WPNGLTLDFHTNTLY	LRP1B	696	Q9NZR2
GHITIYPSWGAAQSK	LAMA3	801	Q16787
SHGTPSQTTAKNWEL	IL15RA	171	Q13261
PSWHLSNLNATTKYK	CHL1	976	O00533
KGNISSQLKHYNPWS	IP6K2	166	Q9UHH9
WTPLHLAAKYGQTNL	MYO16	256	Q9Y6X6
PFGKWTLSSAAQTHQ	GMIP	481	Q9P107
VTTPKYKWGSVTHQS	HERC2	2651	O95714
HGITSYEWSLSPSSK	KIAA0319L	531	Q8IZA0
LHQFSGTETNKIWPY	AK4	191	P27144
QSIGSSLHWYQQKPD	IGKV6-21	46	A0A0C4DH24
LLNSTHLKAYDWGSP	LIPJ	266	Q5W064
FPESKLYWISSGNHT	LRP1	1751	Q07954
VQHWKLLTGNPGYSD	ARSJ	451	Q5FYB0
PINYTGSVLDWSSHF	TMEM63C	156	Q9P1W3
VIIWGNHSSTQYPDV	MDH1	181	P40925
SVQTAEWQAHPLYGS	PCYOX1L	416	Q8NBM8
SKEWIAYLVTPNGSN	KIAA1586	181	Q9HCI6
QSIGSSLHWYQQKPD	IGKV6D-21	46	A0A0A0MT36
HNAWLSYSLLPQSTA	PCDHGC5	601	Q9Y5F6
VYWETGAQITSPHDK	PGM2L1	186	Q6PCE3
GQALYNIISTWPHFK	PGLYRP3	326	Q96LB9
HWTLISGLPTYVAEN	PDE6C	341	P51160
LTDHNPKTYWESNGS	CUL7	856	Q14999
PLGIYDQSTTHWLQG	NRDE2	271	Q9H7Z3
QWKISHTTGIPYNSQ	HERVK_113	726	P63132
WAPTVTKSHLQEYLN	PI4KA	1071	P42356
AWTYDSNTSHPLLAV	EED	151	O75530
FTITSYGIHWVQQSP	IGHV1-38-4	46	P0DTW3
WGIQVTSTEEYPHLK	NDST4	441	Q9H3R1
QRDYSWHPTTSQAKG	OGG1	276	O15527
PQPSSHSRELYTSKW	TMEM63A	381	O94886
SDPAKQVSIHNYTIW	GPR151	141	Q8TDV0
QWKISHTTGIPYNSQ	ERVK-7	726	P63135
QWKISHTTGIPYNSQ	ERVK-6	726	Q9BXR3
QSSSHWNIYSSILPA	RIMS1	1056	Q86UR5
QWKISHTTGIPYNSQ	ERVK-18	726	Q9QC07
PHESYANGINWSAAK	FCN1	296	O00602
SLLIHQGAQLSWYPK	GAL3ST3	31	Q96A11
ETYWQSDGSQPHLVN	ANAPC10	51	Q9UM13
SWLQKASGSLPYTQT	APOB	1236	P04114
LDNGEWTPTLQHYLS	CCNB1	356	P14635
SAHKTAQPNGDWTYQ	HLA-DMB	161	P28068
AQPNGDWTYQTLSHL	HLA-DMB	166	P28068
ASSYLSLTPEQWKSH	IGLL5	176	B9A064
NHKTYWQFLSGVTPL	CBLIF	381	P27352
NSVEKYDPHTGHWTN	KLHL12	441	Q53G59
NDPSLTIKSIGHQWY	MT-CO2	91	P00403
IKVYWNAPSSAPNHT	FRRS1	126	Q6ZNA5
HPQWLSAGQTEASVY	ATG9A	531	Q7Z3C6
SNTLTWALYHLSKDP	CYP27A1	341	Q02318
LLSQWKHYIQCDGSP	DNAI7	91	Q6TDU7
STPSWASDHNYNAVK	DIDO1	501	Q9BTC0
KYWDTPLHAAAQQSS	ASB5	231	Q8WWX0
KTIQGELGWISYPSH	EPHA3	36	P29320
KSPLTHYTIFWTNAQ	CSF3R	556	Q99062
LEPAQGSLHTQSQYW	GHRHR	311	Q02643
GDSNPIYSQIWSIQH	FCRL3	656	Q96P31
LTHPYNKLWSLGQDD	DENND1A	631	Q8TEH3
YGQEEWTNSRHKAPS	KHDRBS3	316	O75525
LNCSHENGTKPSYTW	HEPACAM	166	Q14CZ8
YLPTSSQDHTWVTDN	KRTAP26-1	41	Q6PEX3
TDHNPKTYWESNGST	CUL9	1186	Q8IWT3
FPGIYTTINAHQWSE	COPS8	86	Q99627
QWLKNGRPVHTSSTY	HEPACAM2	181	A8MVW5
YLLKSWSNTSPVGNG	FRY	16	Q5TBA9
HLALYTVTGQSWPES	CCNA2	361	P20248
DQLYTWAAVSQPTHS	FMN2	596	Q9NZ56
NTWGVSLFHLDTYPA	SLC13A4	601	Q9UKG4
GRLLTSSEEPYSWQH	IPO13	451	O94829
PTGSWQLYHVTLKVT	MEP1B	381	Q16820
NTLTISSEHYNQPDW	CACNA1D	536	Q01668
LKKSVPTTWGYNDNS	LGSN	376	Q5TDP6
SWTETHAVNAPTYKL	PTPRK	336	Q15262
NSGWKTIYQVDLPHT	PLEKHM2	966	Q8IWE5
TYWAVSEELLPNSGH	IRF3	291	Q14653
LQGSWELFTTIHTYP	MROH5	966	Q6ZUA9
WYTLLTLPTDTDGNH	FREM3	741	P0C091
SAQLSWLPTNSNYSH	RIMBP2	406	O15034
WSAIIGGSHSKNYVL	SPON1	231	Q9HCB6
IYNAWLSGLPQHIKS	SLC6A16	441	Q9GZN6
QSWYPVIKQEGDHVS	SKIL	376	P12757
ISLHYWNNSTKSLFP	NXPE4	41	Q6UWF7
HKWSSFSSTYLPENI	MKLN1	21	Q9UL63
LTGAYDNTAKIWTHP	PRPF4	466	O43172
RWADNPYVSGTVHTK	SORCS2	506	Q96PQ0
WHQKTYAFSENPLPT	SMARCB1	321	Q12824
SAYPKNSWTHLGADI	PKHD1	2861	P08F94
QYKTLPGWNTDISNA	ADSS2	401	P30520
QNSLDSWGPKVEHTY	ITGA2B	801	P08514
DSSGKKPWQYLTSNT	SOWAHB	701	A6NEL2
AALNWNYESTIHPLS	ADGRF5	21	Q8IZF2
VVWHPSQELLASASY	CIAO1	156	O76071
QPVHGRTDWASKYAS	CILK1	616	Q9UPZ9
FLSQWKISHTTGIPY	ERVK-25	721	P63136
PYSIQTAEKQNWLHS	TDP1	461	Q9NUW8
HNKTPSWDKENGVYT	TULP2	446	O00295
EKQTTTHYADATPLW	UNC13C	521	Q8NB66
YKKPDVNWGSSTQAL	SLC12A2	751	P55011
QWKISHTTGIPYNSQ	ERVK-10	726	P10266
QWKISHTTGIPYNSQ	ERVK-8	726	P63133
EKPNGLLYFWHQSLS	TTC41P	656	Q6P2S7
QWKISHTTGIPYNSQ	ERVK-11	726	Q9UQG0
NHTPWDILTYKQSGS	VPS13C	2981	Q709C8
FVYQSQISHIWPDSG	PKHD1L1	1151	Q86WI1
KNGDWHLEANTSTLY	PKHD1L1	2956	Q86WI1
QPLSGKTSYFHLLTW	SMO	351	Q99835
KWSVAKHTQSYPTDS	TRPM1	41	Q7Z4N2
DYSLWVSSPLKGQHV	TRIML1	386	Q8N9V2
SIHQYLVDEPTLSWS	STRADB	26	Q9C0K7
SWGSLPFLKNSSHQV	SPZ1	46	Q9BXG8
HAATQPDYISWGTQE	TUBG2	436	Q9NRH3
FLSQWKISHTTGIPY	ERVK-19	726	Q9WJR5
SSSQGWGKIVAQYIH	TARBP1	876	Q13395
KGHWANPDLASSLQY	UBR4	3956	Q5T4S7
QTDPSGTYHAWKANA	PSMA7	146	O14818
LHNKAPVWNSDTQSY	TULP3	361	O75386
HGSKTTPNVWYKFSE	nan	61	Q9UFV3