Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of synapse maturation

NEUROD2 NFATC4

3.02e-053662GO:2000297
DomainA/G_cyclase_CS

NPR2 ADCY5

1.52e-0317642IPR018297
DomainNucleotide_cyclase

NPR2 ADCY5

1.71e-0318642IPR029787
Domain-

NPR2 ADCY5

1.71e-03186423.30.70.1230
DomainGUANYLATE_CYCLASE_1

NPR2 ADCY5

1.90e-0319642PS00452
DomainGuanylate_cyc

NPR2 ADCY5

1.90e-0319642PF00211
DomainGUANYLATE_CYCLASE_2

NPR2 ADCY5

1.90e-0319642PS50125
DomainA/G_cyclase

NPR2 ADCY5

1.90e-0319642IPR001054
DomainCYCc

NPR2 ADCY5

1.90e-0319642SM00044
Pubmed

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

SPTBN4 SART1 ZBTB7A NPR2 WWOX MZF1 SUN2 HES6 N4BP3 WWC1

2.16e-051021661026760575
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SART1 ZBTB7A ATXN7L2 POLD1 SUN2 ZNF324 P3H4 WWC1 ARHGAP33 SNAP29

4.59e-051116661031753913
Pubmed

Transcriptional regulation of mouse L-selectin.

MZF1 KLF2

5.29e-05666219041738
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

TGM1 PGS1 NFATC4 MZF1 POLD1 ARMC5 P3H4 WWC1 MEN1

6.10e-0592566928986522
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

SART1 ZBTB7A ZNF689 ZNF324 HES6 ZNF324B SNAPC4 KLF2

1.43e-0480866820412781
Pubmed

Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide.

SETX UBA2

2.31e-041266224244371
Pubmed

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.

C2CD4B ADCY5

2.31e-041266220419449
Pubmed

Menin determines K-RAS proliferative outputs in endocrine cells.

BRAF MEN1

3.67e-041566225133424
Pubmed

Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.

SPTBN4 BFSP1

4.18e-041666221745462
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZBTB7A SETX LEMD3 POLD1 SUN2 RRP15 EIF3A N4BP3 PPP1R12C MEN1

4.96e-041497661031527615
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

PPP2R3A WWOX ARMC5 P3H4 FAM241A SNAP29

5.26e-0453366625544563
Pubmed

Putative Protein Interactome of the Rhomboid Protease RHBDL4.

LEMD3 SNAP29

5.32e-041866236857408
Pubmed

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

ZNF689 ZNF324 ZNF324B

5.38e-048366320562864
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SART1 ZBTB7A EME1 BRAF UBA2 RRP15 SNAPC4

6.56e-0477466715302935
Pubmed

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

C2CD4B ADCY5

6.59e-042066220081858
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SART1 ZBTB7A EME1 SETX ATXN7L2 LEMD3 SUN2 RRP15 MEN1

7.30e-04129466930804502
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SPTBN4 ZFYVE28 KIAA1614

9.52e-0410166310997877
Pubmed

Substrate specificities and identification of putative substrates of ATM kinase family members.

PPP2R3A POLD1

1.03e-032566210608806
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

SPTBN4 DACT1 NEUROD2 DUSP8 APLP1 SNAPC4 LCP2 WWC1

1.27e-03112466821900206
Pubmed

Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1.

DACT1 NEUROD2

1.49e-033066232645484
Pubmed

A census of human transcription factors: function, expression and evolution.

ZBTB7A NEUROD2 NFATC4 MZF1 ZBTB4 SNAPC4 KLF2

1.65e-0390866719274049
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

EME1 PGS1 BRAF ZNF689 ZBTB4

1.66e-0345066516751776
Pubmed

Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.

SART1 EIF3A

1.70e-033266220056645
CytobandEnsembl 112 genes in cytogenetic band chr19q13

SPTBN4 HIPK4 MZF1 POLD1 UBA2 ZNF324 APLP1 ZNF324B ARHGAP33 PPP1R12C

7.57e-0611926610chr19q13
ToppCellCV-Mild-3|Mild / Virus stimulation, Condition and Cluster

PPP2R3A SHF DUSP8 ZNF324B SNAPC4 N4BP3

1.74e-071666665599f90fc0e15a3670b03187085eba91228390a2
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C2CD4B CLIC6 CFAP46 JHY ACSS3

5.86e-06173665a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

LANCL3 UBA2 RRAD ADCY5 PPP1R12C

7.91e-0618466583987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SUN2 ARMC5 KIAA1614 PPP1R12C KLF2

1.18e-0520066524e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SUN2 ARMC5 KIAA1614 PPP1R12C KLF2

1.18e-05200665f7c3a8f5ac156c05ad7335d6d142c154c7d86449
Diseasefamilial non-medullary thyroid cancer

BRAF MEN1

2.68e-054632C4733333
Diseasedisorder of pharynx

ZBTB7A CARMIL2 FAM241A

1.32e-0446633MONDO_0020592
DiseaseNeuroendocrine Tumors

BRAF MEN1

2.44e-0411632C0206754
Diseasedisease progression measurement

WWOX EIF3A ADCY5

3.06e-0461633EFO_0008336
DiseaseAdrenocortical carcinoma

BRAF MEN1

6.71e-0418632C0206686
DiseaseBMI-adjusted fasting blood glucose measurement

C2CD4B ADCY5

1.10e-0323632EFO_0008036
Diseasemean fractional anisotropy measurement

DACT1 DUSP8 KIAA1614

1.12e-0395633EFO_0008399
Diseasedisease free survival, response to mepolizumab

LCP2 HS3ST3A1

1.20e-0324632EFO_0000409, EFO_0008459
Diseaseneutrophil percentage of leukocytes

PPP2R3A ZNF689 SNAPC4 ADCY5 FAM241A KLF2

1.91e-03610636EFO_0007990

Protein segments in the cluster

PeptideGeneStartEntry
LGRRDSSDDWEIPDG

BRAF

441

P15056
AARAEPRDARTGWPE

DUSP8

561

Q13202
QDRLWAPEEDPATEG

CARMIL2

1071

Q6F5E8
WPPGSRVEGAEDEEE

APLP1

231

P51693
ASPSEDEWRRGGEPR

CFAP46

2541

Q8IYW2
GREAASWDFPEERTP

ARMC5

431

Q96C12
SWDFPEERTPERAQG

ARMC5

436

Q96C12
ERCWAQDPAERPDFG

NPR2

766

P20594
SRWRSDDDDDPPLSG

ADCY5

71

O95622
RSPGELAWDAAEEAE

CLIC6

321

Q96NY7
SWVERADLPAADGAE

ATXN7L2

31

Q5T6C5
EERDPAPWRDNGDDK

RBM20

686

Q5T481
APGRDRVGREDEDGW

HES6

6

Q96HZ4
AKTRDGDFEDPPEWV

ZFYVE28

801

Q9HCC9
DGEERDPETEEPLWA

LEMD3

226

Q9Y2U8
EAEEPWGEEAREGRR

MEN1

471

O00255
QGPRLDWPEDSEDSL

RRAD

66

P55042
PDSLDEEESPRWGSL

JHY

71

Q6NUN7
SPEDDRPCRGSSWEE

HIPK4

511

Q8NE63
LPLPEGWEEARDFDG

WWC1

6

Q8IX03
DSEAWPGVLDSERDR

WWC1

326

Q8IX03
SWDTAAPERPVGDVD

KIAA1614

326

Q5VZ46
ESDLWPRAADEDAGR

C2CD4B

61

A6NLJ0
PRAADEDAGRTDWDP

C2CD4B

66

A6NLJ0
DAAAAGDRRPAPDTW

PGS1

336

Q32NB8
AERAAGGEAPSLEDW

PEAK3

436

Q6ZS72
DACARAEEWGEPDAD

LANCL3

101

Q6ZV70
AEEWGEPDADTRAAF

LANCL3

106

Q6ZV70
PPAPRDDGEEAAWEE

HS3ST3A1

101

Q9Y663
VENDGPEPSDWDRFA

PPP2R3A

1076

Q06190
RDRWSSEDEEAAGPS

PTPN20

91

Q4JDL3
AWLDDGDELDFSPPR

ARHGAP33

716

O14559
DREELSAAPDPGWPD

GYG1

116

P46976
EPEGRWREKGEADTE

DACT1

26

Q9NYF0
RGLDDDRGPWRNADD

EIF3A

1111

Q14152
DALAEREAAGTGWDP

FAM241A

21

Q8N8J7
ASRAAEPERPADEGW

BFSP1

21

Q12934
RAGPSEDREDWVEEP

EME1

296

Q96AY2
GLWDDDDAPRPSQFE

POLD1

21

P28340
GDHGPVARDDDPFWD

KIF28P

616

B7ZC32
PLERGDPEWSSETDA

TMEM179B

196

Q7Z7N9
EWRGPAEGEEAEPAD

PPP1R12C

631

Q9BZL4
LEDNPDAWGDGSPRD

NFATC4

131

Q14934
DRDAAWELEPGAFSD

PHF7

226

Q9BWX1
KAEEPGDRPAEEWLG

SFT2D3

31

Q587I9
FDDDGEDEGARPAPW

SNAP29

11

O95721
EDEGARPAPWRDARD

SNAP29

16

O95721
READDDSVDPFWPAL

SETX

276

Q7Z333
ADPEAAWEPTEAEAR

UBA2

211

Q9UBT2
SPLGSSDRAWRDPDE

AKR1A1

211

P14550
EAVPLAPGRDLDWDE

ACSS3

261

Q9H6R3
GAPWPRESRLPEDDE

SHF

181

Q7M4L6
EDRDVSGEWPRAFPD

ZNF324

86

O75467
AKDSRRPDEGWEARD

SUN2

251

Q9UH99
RPDEGWEARDSSPHF

SUN2

256

Q9UH99
PERLAGPEESAWGDE

SHC2

316

P98077
AAKPDPDGGRADEWA

P3H4

86

Q92791
GEWEGDRAEAQAPDL

ZBTB4

211

Q9P1Z0
DTDSEDELPPGWEER

WWOX

11

Q9NZC7
ESPDRGWEREQPAAS

SPTBN4

26

Q9H254
DWDKESDGPDDSRPE

RRP15

261

Q9Y3B9
QRGWEEDEDPERKGA

SART1

536

O43290
LERNTDDWEPAALDP

ZNF689

81

Q96CS4
PPISEEERWGEASND

SNAPC4

56

Q5SXM2
AADDDWGPEPSDSRG

TGM1

56

P22735
EGDSNPGLWPERDED

ZBTB7A

236

O95365
EDRDVSGEWPRAFPD

ZNF324B

86

Q6AW86
RWPRAEPESGGTDDD

KLF2

26

Q9Y5W3
GWGPDRRENDEDDVH

LCP2

311

Q13094
ADPSARPEEEARWEV

N4BP3

356

O15049
DSEEEGEAALWDPGP

MZF1

26

P28698
PKFASWGDGEDDEPR

NEUROD2

16

Q15784