Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionclathrin light chain binding

CLTCL1 CLTC

1.85e-047602GO:0032051
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC3 ABCA12

3.15e-049602GO:0034040
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 ABCA6 ABCA12 SLFN13 NLRP1 MORC4 ATP5F1C

3.44e-04441607GO:0016887
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC3 ABCA6 ABCA12

4.31e-0449603GO:0140359
GeneOntologyMolecularFunctionATP-dependent activity

ABCC3 ABCA6 CENPE ABCA12 SLFN13 NLRP1 MORC4 ATP5F1C

4.77e-04614608GO:0140657
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

1.05e-052612IPR022365
DomainClathrin-link

CLTCL1 CLTC

1.05e-052612PF09268
Domain-

CLTCL1 CLTC

1.05e-0526122.130.10.110
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

1.05e-052612IPR016025
DomainClathrin_propel

CLTCL1 CLTC

1.05e-052612PF01394
DomainClathrin_heavy_chain

CLTCL1 CLTC

1.05e-052612IPR016341
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

1.05e-052612IPR015348
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

1.05e-052612IPR001473
DomainClathrin_H-chain_linker

CLTCL1 CLTC

3.14e-053612IPR012331
DomainCLH

CLTCL1 CLTC

3.14e-053612SM00299
DomainDUF1981

ARFGEF2 ARFGEF1

6.27e-054612PF09324
DomainSec7_N

ARFGEF2 ARFGEF1

6.27e-054612IPR032691
DomainSec7_N

ARFGEF2 ARFGEF1

6.27e-054612PF12783
DomainDCB_dom

ARFGEF2 ARFGEF1

6.27e-054612IPR032629
DomainDCB

ARFGEF2 ARFGEF1

6.27e-054612PF16213
DomainSec7_C

ARFGEF2 ARFGEF1

6.27e-054612IPR015403
DomainClathrin

CLTCL1 CLTC

2.18e-047612PF00637
DomainCHCR

CLTCL1 CLTC

2.18e-047612PS50236
DomainClathrin_H-chain/VPS_repeat

CLTCL1 CLTC

2.90e-048612IPR000547
DomainABC_tran

ABCC3 ABCA6 ABCA12

5.16e-0448613PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCA6 ABCA12

5.16e-0448613PS50893
DomainABC_TRANSPORTER_1

ABCC3 ABCA6 ABCA12

5.49e-0449613PS00211
DomainABC_transporter-like

ABCC3 ABCA6 ABCA12

5.82e-0450613IPR003439
DomainABC_A

ABCA6 ABCA12

6.78e-0412612IPR026082
Domain-

ARFGEF2 ARFGEF1

1.07e-03156121.10.1000.11
DomainSec7

ARFGEF2 ARFGEF1

1.07e-0315612PF01369
DomainSec7_alpha_orthog

ARFGEF2 ARFGEF1

1.07e-0315612IPR023394
DomainSec7

ARFGEF2 ARFGEF1

1.22e-0316612SM00222
DomainSEC7

ARFGEF2 ARFGEF1

1.22e-0316612PS50190
DomainSec7_dom

ARFGEF2 ARFGEF1

1.22e-0316612IPR000904
DomainCARD

CARD9 NLRP1

3.76e-0328612PF00619
DomainCARD

CARD9 NLRP1

4.59e-0331612IPR001315
DomainARM-type_fold

CLTCL1 CLTC ARFGEF2 ARFGEF1 LYST

4.96e-03339615IPR016024
DomainCARD

CARD9 NLRP1

5.19e-0333612PS50209
DomainABC_transporter_CS

ABCC3 ABCA12

8.31e-0342612IPR017871
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

3.13e-06262220065094
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

3.13e-0626228733129
Pubmed

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

ARFGEF2 ARFGEF1

3.13e-06262217360629
Pubmed

Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.

ARFGEF2 ARFGEF1

3.13e-06262210716990
Pubmed

Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.

ARFGEF2 ARFGEF1

3.13e-06262218203920
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

3.13e-06262229097553
Pubmed

Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

3.13e-06262210212200
Pubmed

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

ARFGEF2 ARFGEF1

3.13e-06262223918382
Pubmed

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.

ARFGEF2 ARFGEF1

3.13e-06262218417613
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC3 ABCA6 ABCA12

8.11e-06226238894702
Pubmed

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

ARFGEF2 ARFGEF1

9.37e-06362219332778
Pubmed

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

CLTCL1 CLTC

9.37e-06362219509056
Pubmed

Specific functions of BIG1 and BIG2 in endomembrane organization.

ARFGEF2 ARFGEF1

9.37e-06362220360857
Pubmed

A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase.

ARFGEF2 ARFGEF1

9.37e-06362218832381
Pubmed

Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.

CLTCL1 CLTC

9.37e-06362215133132
Pubmed

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

9.37e-06362216866877
Pubmed

Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG.

CLTCL1 CLTC

9.37e-06362222891263
Pubmed

Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis.

ARFGEF2 ARFGEF1

9.37e-06362231199673
Pubmed

Distinct functions for Arf guanine nucleotide exchange factors at the Golgi complex: GBF1 and BIGs are required for assembly and maintenance of the Golgi stack and trans-Golgi network, respectively.

ARFGEF2 ARFGEF1

9.37e-06362218003980
Pubmed

Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.

ARFGEF2 ARFGEF1

9.37e-06362227162341
Pubmed

The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN).

ARFGEF2 ARFGEF1

9.37e-06362223386609
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HIVEP2 CEP85L CLTC NGEF CHMP3 ARFGEF2 ANKRD36 REV3L TXLNG PCM1 ITGB3BP

1.51e-051285621135914814
Pubmed

Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2).

ARFGEF2 ARFGEF1

1.87e-05462212571360
Pubmed

Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing.

ARFGEF2 ARFGEF1

1.87e-05462222084092
Pubmed

Dab2 links CIN85 with clathrin-mediated receptor internalization.

CLTC CBL

1.87e-05462214596919
Pubmed

Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members.

ARFGEF2 ARFGEF1

1.87e-05462211013081
Pubmed

Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy.

CLTC CBL

1.87e-05462235614042
Pubmed

Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506.

ARFGEF2 ARFGEF1

1.87e-05462212606707
Pubmed

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.

CLTCL1 CLTC

1.87e-05462211517213
Pubmed

Distinct PAR/IQGAP expression patterns during murine development: implications for thrombin-associated cytoskeletal reorganization.

IQGAP2 F2R

3.12e-05562215457341
Pubmed

Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.

CLTCL1 CLTC

3.12e-05562210436022
Pubmed

Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.

CENPU ITGB3BP

3.12e-05562223028590
Pubmed

Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery.

CLTC CHMP3

4.67e-05662216431367
Pubmed

A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism.

CLTCL1 CLTC

6.53e-05762219478182
Pubmed

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.

MORC4 TBC1D8B

6.53e-05762223143602
Pubmed

Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock.

RPS6KB1 CBL

6.53e-05762220622121
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

IQGAP2 SLFN13 CLTC ARFGEF2 ARFGEF1 FAM135A PCM1 ATP5F1C

6.98e-0577762835844135
Pubmed

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

LYST PCM1

8.69e-05862229946151
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

CLTCL1 TRIM4 RPS6KB1 CLTC MASTL PACS2 ALG13 ATP5F1C

9.08e-0580762830575818
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

CLTCL1 CLTC ARFGEF2 ARFGEF1 TXLNG ATP5F1C

9.23e-0541162636652389
Pubmed

Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation.

CLTC CBL

1.12e-04962217182860
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCA6 ABCA12

1.39e-041062211435397
Pubmed

Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics.

CLTC PCM1

1.39e-041062221956701
Pubmed

CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.

CLTCL1 CLTC

1.39e-041062225898166
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SIKE1 DENND4A CBL PCM1 ALG13 ATP5F1C

1.44e-0444662624255178
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

SIKE1 MID2 ARFGEF2 PCM1 ATP5F1C

1.58e-0428562532838362
Pubmed

Purification and identification of protein-tyrosine kinase-binding proteins using synthetic phosphopeptides as affinity reagents.

CLTC CBL

1.70e-041162215215307
Pubmed

Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion.

CLTCL1 CLTC

1.70e-041162229604273
Pubmed

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells.

RPS6KB1 F2R

1.70e-041162218398001
Pubmed

EphrinA2 regulates clathrin mediated KSHV endocytosis in fibroblast cells by coordinating integrin-associated signaling and c-Cbl directed polyubiquitination.

CLTC CBL

2.41e-041362223874206
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

RPS6KB1 RBM26 MASTL CBL TXLNG PCM1

2.75e-0450362616964243
Pubmed

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.

CENPU ITGB3BP

3.23e-041562216622420
Pubmed

Structural insights into human CCAN complex assembled onto DNA.

CENPU ITGB3BP

4.18e-041762236085283
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TRIM4 CLTC RBM26 DACH1 CBL PCM1

4.38e-0454962638280479
Pubmed

The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.

CLTC CBL

4.70e-041862210567358
Pubmed

Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

CBL ATP5F1C

4.70e-041862219531499
Pubmed

A crucial role for Arf6 in the response of commissural axons to Slit.

ARFGEF2 ARFGEF1

5.24e-041962230674481
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ABCC3 IQGAP2 ARFGEF2 ARFGEF1 TXLNG FAM135A

5.28e-0456962630639242
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

CENPE HASPIN CENPU PCM1

5.48e-0421062416565220
Pubmed

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.

CEP85L CBL

5.82e-042062231591574
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CASP8AP2 CENPE CLTC MORC4 FAM135A PCM1

6.27e-0458862638580884
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

HIVEP2 CLTCL1 CLTC PCM1

7.21e-0422662425900982
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

IQGAP2 CENPE HASPIN F2R

7.33e-0422762426410627
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

XIRP2 DACH1 MAGEE1 TBC1D8B

8.08e-0423362437704626
Pubmed

An unappreciated role for RNA surveillance.

ABCC3 CMKLR1 LYST

8.17e-0410262314759258
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

IQGAP2 CLTC CHMP3 TXLNG PCM1 ATP5F1C

8.68e-0462662633644029
Pubmed

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.

CLTCL1 CLTC

9.89e-042662224067654
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

CEP85L CLTC CBL

1.04e-0311162322558309
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

DENND4A CLTC FER CBL

1.13e-0325562415324660
Pubmed

Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.

CLTCL1 CLTC

1.32e-033062222963397
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

RBM26 NGEF CCDC168

1.40e-0312362326912792
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

EEFSEC CLTC RBM26 TBC1D8B PCM1 ATP5F1C

1.55e-0370162630196744
Pubmed

Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.

FER CBL

1.59e-033362218271526
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

CLTC PACS2 CBL

1.72e-0313262316944949
Pubmed

A human MAP kinase interactome.

CASP8AP2 HIVEP2 CLTC CBL TXLNG

1.76e-0348662520936779
CytobandXq22.3

MID2 PWWP3B MORC4 TBC1D8B

1.20e-0733624Xq22.3
CytobandEnsembl 112 genes in cytogenetic band chrXq22

MID2 PWWP3B MORC4 TBC1D8B

8.96e-05172624chrXq22
GeneFamilyATP binding cassette subfamily A

ABCA6 ABCA12

4.27e-0414402805
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

CARD9 NLRP1

2.00e-0330402959
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CASP8AP2 IQGAP2 CENPE RBM26 FER CENPU ARFGEF1 EXT1 REV3L PCM1 ITGB3BP

2.98e-076566111M18979
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_UP

EEFSEC COPZ2 CENPE HASPIN CENPU ZFAND4

7.17e-06200616M6647
CoexpressionGSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_DN

RPS6KB1 ARFGEF1 UGT2B15 CMKLR1 TXLNG ALG13

7.17e-06200616M7240
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP

CASP8AP2 CENPE SLFN13 HASPIN CENPU MASTL ZFAND4

4.05e-05402617MM454
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

SERPINB8 CENPE CEP85L RPS6KB1 RBM26 ARFGEF2 ARFGEF1 REV3L FAM135A ZFAND4 PCM1

3.05e-084326011Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

CASP8AP2 RBM44 DENND4A HASPIN MASTL ARFGEF2 LYST TXLNG FAM135A ZFAND4 ALG13

1.62e-058206011gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CASP8AP2 CENPE CEP85L RPS6KB1 RBM26 CENPU MASTL ARFGEF2 NLRP1 PWWP3B REV3L PCM1 ITGB3BP

3.92e-0512576013facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

CASP8AP2 CENPE CEP85L RPS6KB1 RBM26 DACH1 CENPU MASTL ARFGEF2 NLRP1 PWWP3B REV3L PCM1 ITGB3BP

4.26e-0514596014facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

CASP8AP2 RBM44 HASPIN MASTL ARFGEF2 TXLNG FAM135A

6.90e-05361607gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlaskidney_e15.5_SmlBldVes_Tie2_top-relative-expression-ranked_1000

ABCC3 HIVEP2 MID2 CENPE SLFN13 HASPIN CMKLR1 MORC4 F2R ITGB3BP

8.51e-058136010gudmap_kidney_e15.5_SmlBldVes_Tie2_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

SERPINB8 CENPE CEP85L RPS6KB1 RBM26 ARFGEF2 ARFGEF1 REV3L FAM135A ZFAND4 PCM1

8.91e-059896011Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_1000

CENPE CENPU MASTL PWWP3B

1.71e-0498604gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_1000
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-Mesoderm|GW26 / Sample Type, Dataset, Time_group, and Cell type.

EEFSEC XIRP2 DACH1 C12orf60

2.59e-07396243479d255b87fa8042c51d80a3eb81a774850132e
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

CLTCL1 CENPE DACH1 CENPU MASTL CCDC168

3.47e-07199626e222b90caf45904d8f763574e7b6aac13333df92
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IQGAP2 XIRP2 SLFN13 CCDC168 TBC1D8B

2.85e-06159625bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 CEP85L DACH1 LYST PCM1

4.94e-0617862501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPU MASTL F2R ZFAND4

5.08e-06179625dabecd283c1f0f71a66b804c99be8bd48ea36e35
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM44 IQGAP2 CENPE HASPIN MASTL

6.78e-06190625b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLTCL1 DACH1 ARFGEF1 PWWP3B CLEC12A

6.78e-06190625896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

DENND4A ARFGEF1 NLRP1 ANKRD36 PCM1

7.14e-0619262547646d7e4990be85072987f92bf18d52f8da752e
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CENPE SLFN13 HASPIN CENPU MASTL

7.50e-061946254d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 CENPE DACH1 CENPU MASTL

7.89e-061966255905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell(3)_MNP-(3)_Macrophage_Dividing|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

CENPE SLFN13 HASPIN CENPU ITGB3BP

8.08e-06197625048bc4f8fd5d4f394e2384700640f72042336597
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IQGAP2 ABCA6 DACH1 COL6A5 F2R

8.49e-06199625615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CENPE SLFN13 HASPIN CENPU ITGB3BP

8.70e-062006252afbb5b5742b956993796621fea7e0c9888754a1
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CENPE SLFN13 HASPIN CENPU ITGB3BP

8.70e-062006254462ebd5d4632788f10a93fadd2babae701c754f
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

DENND4A HIVEP2 ANKRD36 GARIN2

6.63e-051566241545169694f686d28648a68b552c2ae606599d66
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP8AP2 RBM44 IQGAP2 NLRP1

6.80e-05157624eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-pDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQGAP2 NLRP1 CMKLR1 CLEC12A

7.32e-05160624dee756a2dc9725520d439e7273c489c2284015d8
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE DACH1 CENPU ITGB3BP

7.86e-05163624466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COPZ2 CENPE CENPU ITGB3BP

8.64e-051676249280558baddea51aae47f3383d895a9b0c6749a4
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM44 IQGAP2 CENPE MASTL

8.64e-05167624d21635df8b74189e3309eaf435af381fbe412574
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA12 SLFN13 CENPU MASTL

9.04e-05169624121768fc51fc3441ec725346a1bbe29e21d05971
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IQGAP2 SLFN13 CENPU F2R

9.68e-0517262486f52f486d67217fc1b8443ab362c975df2974a4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IQGAP2 SLFN13 CENPU F2R

9.68e-05172624fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IQGAP2 SLFN13 CENPU F2R

9.68e-05172624e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPINB8 CENPE CENPU TBC1D8B

1.01e-041746241779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCellwk_20-22-Hematologic-Myeloid-Promonocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SERPINB8 CENPE LYST CLEC12A

1.03e-04175624654299df246debe0a5b12f0d9568eb828bb94bb9
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM44 IQGAP2 CENPE HASPIN

1.03e-04175624ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 FER LYST PCM1

1.06e-04176624749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DENND4A ARFGEF1 ZNF75D FAM135A

1.13e-0417962487f608b137aae34572b150492a83a3a127cff40b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 SLFN13 HASPIN CENPU

1.13e-0417962488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE HASPIN CENPU F2R

1.15e-04180624852e0ea2da58605b059d533dc3fae368709e879a
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CENPE HASPIN CENPU ITGB3BP

1.15e-04180624334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

SERPINB8 ARFGEF1 C12orf60 F2R

1.25e-041846249c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE HASPIN CENPU MASTL

1.31e-041866249feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE HASPIN CENPU MASTL

1.31e-0418662489f5b06bc56674af304912d481ac697c7c870904
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DENND4A CEP85L ARFGEF1 ANKRD36

1.36e-04188624ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPE HASPIN CENPU CCDC168

1.36e-04188624319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE HASPIN CENPU MASTL

1.39e-04189624bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE HASPIN CENPU MASTL

1.39e-0418962496f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellmild-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLTCL1 DACH1 ZNF75D CLEC12A

1.39e-0418962494dd5d4d815449feff7ce157fe7f8234f7c81422
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo|lymph-node_spleen / Manually curated celltypes from each tissue

CENPE CENPU F2R LYST

1.42e-041906244225bfa10a6fb909a3ba8ac26f3541c390b46737
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SERPINB8 CENPU ANKRD36 MORC4

1.42e-04190624651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPE CENPU MASTL ITGB3BP

1.42e-04190624b69940d16685249167d4c2cf6ad8237ccf6f7590
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

ABCC3 ABCA6 SLFN13 DACH1

1.42e-0419062462a3ec1ae0829602b0569cc051210551644f1d46
ToppCellcontrol-Myeloid-Immature_Neutrophils_1|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLTCL1 DACH1 ARFGEF1 CLEC12A

1.42e-0419062438e83337c70c8734b63f8589ba59e0f98603f94c
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-Cycling_NK|lymph-node_spleen / Manually curated celltypes from each tissue

CENPE SLFN13 HASPIN CENPU

1.42e-04190624451eaceb0cb0ec6cfcae00253c0e5c92a168c2f3
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A RPS6KB1 ARFGEF2 PCM1

1.45e-041916241ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellMild-T/NK_proliferative|World / Disease group and Cell class

CENPE CENPU MASTL ITGB3BP

1.45e-041916249dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCellcontrol-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ABCC3 LYST CLEC12A ATP5F1C

1.45e-041916247122957972f177a1d846d965cef53cfe7568ba54
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

IQGAP2 CENPE CMKLR1 CLEC12A

1.48e-04192624a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCelldroplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE HASPIN CENPU MASTL

1.48e-0419262496f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCellProliferating|World / shred by cell class for mouse tongue

CENPE HASPIN CENPU MASTL

1.48e-04192624f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCellSevere_COVID-19-Myeloid-proliferating_Myeloid_cells|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CENPE HASPIN CENPU ITGB3BP

1.51e-041936240d85025690c9cd545cba30abc38acbdd6a39b153
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-MPO+_mono-neutrophil|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPINB8 CARD9 LYST CLEC12A

1.51e-0419362435998200890fef12e7f4a3dc65eca1c30d19fa93
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE HASPIN CENPU ITGB3BP

1.51e-04193624cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPE HASPIN CENPU ITGB3BP

1.54e-04194624cb39850e9577015b6b9834e98c36b412bae7d462
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPE HASPIN CENPU ITGB3BP

1.54e-04194624408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CENPE HASPIN CENPU ITGB3BP

1.54e-04194624193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPE HASPIN CENPU ITGB3BP

1.54e-041946242360b5f995b360419de41612368cab9fb61781a1
ToppCell3'_v3-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

CENPE SLFN13 HASPIN CENPU

1.54e-04194624bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CENPE HASPIN CENPU ITGB3BP

1.54e-04194624903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CENPE HASPIN CENPU ITGB3BP

1.54e-0419462458406502a8cbcc3037f79a1b6a683df408297ae5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLFN13 CENPU MASTL ITGB3BP

1.54e-041946244c1d13d8cb6fb424655c67755ee6dbaf59d6b418
ToppCellBLOOD--(1)_T_cell-(1)_Activated_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IQGAP2 CENPE HASPIN CENPU

1.54e-041946246a0cbb9d5c5c4effb02dff654c6c3b184026875c
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CENPU ANKRD36 REV3L PCM1

1.54e-04194624dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 CENPU MASTL ITGB3BP

1.57e-04195624b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE SLFN13 HASPIN CENPU

1.57e-0419562475759fd7f925725f0ecd07214afcca5aa2158f9e
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLTC ARFGEF1 REV3L PCM1

1.57e-041956243e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPU MASTL ITGB3BP

1.57e-04195624b57132802cb977551e214880984f3edcd375474f
ToppCellwk_15-18-Hematologic-Myeloid-Promonocyte-like|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SERPINB8 CENPE LYST CLEC12A

1.57e-0419562437b4f635b71734c6e0bc808a739af4bbe6bb47f6
ToppCellsevere-Myeloid-Immature_Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLTCL1 DACH1 ARFGEF1 CLEC12A

1.57e-04195624becad890a420267ca41e98e61a8da343b51e1945
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A ANKRD36 PCM1 ALG13

1.57e-04195624ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 CENPU MASTL ITGB3BP

1.57e-0419562456d8734d020b3da08a5aa9e67999706a9e023a99
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLTC ARFGEF1 REV3L PCM1

1.57e-041956247796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CENPE SLFN13 HASPIN CENPU

1.60e-041966249591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 CENPU MASTL ITGB3BP

1.60e-04196624df366d76ea55f49e349d622effa57c1535df8400
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 DACH1 EXT1 REV3L

1.60e-041966242b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CENPE CENPU MASTL ITGB3BP

1.60e-0419662473f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell(001)_CD16+_Monocyte|World / immune cells in Peripheral Blood (logTPM normalization)

ABCC3 CARD9 LYST CLEC12A

1.60e-0419662433843d550cbca03c044d593b1f6972e4d3871f7f
ToppCellBLOOD--(3)_Non_classical_monocytes| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ABCC3 CARD9 LYST CLEC12A

1.60e-04196624b5ce99e27c9e87be52c10c022a665bf4df0e8b05
ToppCellMultiple_Sclerosis-Myeloid-CD16_Mono|Multiple_Sclerosis / Disease, Lineage and Cell Type

ABCC3 CARD9 LYST CLEC12A

1.60e-0419662483011b56780295dff5ded57064b07dcd2f19ea26
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE CENPU FLACC1 ITGB3BP

1.60e-04196624de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPE HASPIN CENPU MASTL

1.63e-041976247eb4c1cffd0366204af7e63adc8f751685601a94
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

IQGAP2 NLRP1 CBL CLEC12A

1.63e-04197624f18807124b91310fcd84238484a80ecdba684679
ToppCellPCW_10-12|World / Celltypes from embryonic and fetal-stage human lung

DENND4A HIVEP2 ABCA6 DACH1

1.63e-0419762447fd8b0d596c5db1a722473c8efbb17a6bbe7538
ToppCellImmune|World / Lineage, Cell type, age group and donor

IQGAP2 NLRP1 CBL CLEC12A

1.66e-0419862465681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCell(0)_NK_cells-(0)_NK_Dividing|(0)_NK_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CENPE CENPU MASTL ITGB3BP

1.66e-04198624d9cdbc7d420472cb1ffb36ad9c8e53a61b7dbdeb
ToppCellsevere-Myeloid-Immature_Neutrophils_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLTCL1 CENPE SLFN13 CENPU

1.66e-04198624844f534551483c89ef789d1cfeb4680e54f794b2
ToppCellsevere-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLTCL1 CENPE SLFN13 CENPU

1.66e-04198624e36303628af3139310c1d7a84d2919b7319bbda4
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CENPE SLFN13 CENPU ITGB3BP

1.66e-041986246a10bb81817ab606f1f5a2bd8cfe77ef2fb3f2fb
ToppCelldistal-1-Hematologic-Proliferating_Macrophage|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CENPE HASPIN CENPU MASTL

1.66e-04198624df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCelldistal-Hematologic-Proliferating_Macrophage-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CENPE HASPIN CENPU MASTL

1.66e-041986242b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA6 DACH1 COL6A5 F2R

1.66e-041986247582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CENPE SLFN13 CENPU ITGB3BP

1.66e-04198624281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCellmLN-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

CENPE SLFN13 DACH1 CENPU

1.69e-04199624c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLFN13 ARFGEF1 ANKRD36 PCM1

1.69e-04199624f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellMNPs-Dividing_Macrophages|MNPs / lung cells shred on cell class, cell subclass, sample id

CENPE SLFN13 CENPU ITGB3BP

1.69e-041996245952980d0ece5d73f3e9f340c56a38b34d2f2309
ToppCellCOVID-19-Lymphoid-Proliferating_CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

CENPE CENPU MASTL ITGB3BP

1.69e-041996242e9ee10a069afca5dbd9f0863cf90a66db1a6ffb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE SLFN13 CENPU ITGB3BP

1.69e-041996244af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCellcontrol-Lymphocytic-NK_cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

IQGAP2 SLFN13 CMKLR1 F2R

1.69e-041996248aca7775b3d34fd26c7b23ddb23f5f2df72684b0
DrugL-685-818

CLTCL1 CLTC ARFGEF2 ARFGEF1

3.51e-0722624CID000003850
DrugBadg

CLTCL1 CLTC

7.30e-062622CID000125951
DiseaseAnthracosis

RBM26 FLACC1

1.17e-048612C0003165
Diseasesevere acute respiratory syndrome, COVID-19

ABCC3 RBM26 FER DHRSX LYST ITGB3BP

3.21e-04447616EFO_0000694, MONDO_0100096
Diseasepancreatitis

PWWP3B MORC4

4.95e-0416612EFO_0000278
Diseaseacute pancreatitis

MORC4 TBC1D8B

6.30e-0418612EFO_1000652
Diseasealcoholic pancreatitis

PWWP3B MORC4 TBC1D8B

1.11e-0398613EFO_1002013
Diseaseepiandrosterone sulfate measurement

TRIM4 UGT2B15

1.22e-0325612EFO_0021120
Diseaselifestyle measurement

HIVEP2 NGEF ARFGEF2 EXT1

1.43e-03235614EFO_0010724
Diseaseendometrial carcinoma

EEFSEC CASP8AP2 EXT1

1.67e-03113613EFO_1001512
DiseaseMental Retardation, X-Linked 1

MID2 ALG13

2.00e-0332612C2931498
Diseaseandrosterone sulfate measurement

TRIM4 UGT2B15

2.13e-0333612EFO_0021117

Protein segments in the cluster

PeptideGeneStartEntry
KSTEVMKAMQSLVKI

CHMP3

106

Q9Y3E7
IVISEMDIKQQKKMF

ALG13

576

Q9NP73
KNNKVTMETLTKFMQ

ABCA12

2491

Q86UK0
PQVKNKMTKEQYIKM

ARFGEF1

841

Q9Y6D6
MKEQMVFEKNVFNKT

COPZ2

71

Q9P299
VKVVKKADMINKNMT

MASTL

61

Q96GX5
NVTKERKKSKNLMKM

ABCA6

241

Q8N139
PQVKNKMTKEQYIKM

ARFGEF2

786

Q9Y6D5
KEQFIKMLKESQMLT

CENPU

286

Q71F23
KMLKESQMLTNLKRK

CENPU

291

Q71F23
QKQSQMKDIEKMYKS

ANKRD36

1691

A6QL64
TQLLMTEVMKLQKKV

CARD9

116

Q9H257
QMKELMKKFKEIQTQ

CASP8AP2

86

Q9UKL3
AMKVKKIKLEAMSNY

DACH1

341

Q9UI36
KTAYDVLKKMQSKKM

DENND4A

791

Q7Z401
TQKMLISKLEKNKTM

RBM26

751

Q5T8P6
VLKMKIYTENMKSQI

RBM44

321

Q6ZP01
VKMRAFQVKQMKLKD

ABCC3

471

O15438
LETTKMKILKFMAKI

MAGEE1

661

Q9HCI5
LQQKKKMTKKFEMES

FLACC1

256

Q96Q35
KVKVTKLMKTMKSEN

FAM135A

491

Q9P2D6
KLMKTMKSENTKKLI

FAM135A

496

Q9P2D6
LFSKMRVLQEKKQKM

PCM1

396

Q15154
MQQMKRKEKLTLTSK

NLRP1

531

Q9C000
TGKIFAMKVLKKAMI

RPS6KB1

116

P23443
AMKVLKKAMIVRNAK

RPS6KB1

121

P23443
SMTVVTKEKNKKVMF

PACS2

801

Q86VP3
IMAIVVFILKMKVKK

F2R

121

P25116
FLKREMQKTKELMTK

ITGB3BP

131

Q13352
KVTQKKQYKETMMGQ

EXT1

671

Q16394
TMMIKDKQQVKKSYI

FER

101

P16591
KMKIFMKNLLTKIQI

COL6A5

646

A8TX70
MTSIRQFVQKFKMKK

DHRSX

106

Q8N5I4
QGKLSKEKLTTQKMM

CEP85L

641

Q5SZL2
ALINSVMKIMSTVKK

LYST

471

Q99698
VMKIMSTVKKVKSEQ

LYST

476

Q99698
KMLKQMTFKTKCNTP

HASPIN

751

Q8TF76
KSIKNIQKITKSMKM

ATP5F1C

36

P36542
IQKITKSMKMVAAAK

ATP5F1C

41

P36542
RVFMENLMKKTKQTI

CBL

116

P22681
QFSSKKLFSMMKTNK

CCDC168

191

Q8NDH2
QYQSKLLKAMRKKMV

SLFN13

821

Q68D06
LKEKMKELATTYKQM

CENPE

651

Q02224
MKKNTSKTTMRINKQ

GARIN2

1

Q8N9W8
MAVTSQTKKMSFQKI

PWWP3B

526

Q5H9M0
MKMFDKVKVNVNLLI

IQGAP2

1551

Q13576
MKIFLRQKKVTTQMI

MORC4

281

Q8TE76
QMISIQKKMEFKIKS

NGEF

466

Q8N5V2
SKYRKQMLQLMVAKK

SIKE1

106

Q9BRV8
VKDSMKKMFGKNQVI

OR5T2

336

Q8NGG2
KTNEEKKTVQMMFKE

SERPINB8

186

P50452
VIIIATFKMKKTVNM

CMKLR1

61

Q99788
KTLQIFNIEMKSKMK

CLTC

86

Q00610
KTLQIFNIEMKSKMK

CLTCL1

86

P53675
QKAIKTMEMNISVFK

C12orf60

226

Q5U649
VTLKIEMKKMNKLQN

CLEC12A

66

Q5QGZ9
KITTSKDQKKVMVMT

XIRP2

2281

A4UGR9
RQAAIDKMTKKMQKT

EEFSEC

156

P57772
DKMTKKMQKTLENTK

EEFSEC

161

P57772
EEILKTRFMVKQSMK

REV3L

2691

O60673
TLNSKMLKEKMKEQS

TBC1D8B

446

Q0IIM8
EVSKKTRMKIAQKTM

ZNF75D

301

P51815
AVLNKKLMMKLQESK

UGT2B15

131

P54855
RKQMIAVKIKETKVM

MID2

296

Q9UJV3
LKSQRNLVAKMKKVM

TRIM4

161

Q9C037
ENSITMNKMKLLKAK

ZFAND4

216

Q86XD8
FMETKQQKRVKEEKM

HIVEP2

1451

P31629
TTFRQEMEKMTKKIK

TXLNG

376

Q9NUQ3