Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-1A adrenergic receptor binding	ARRB1 ARRB2	2.48e-05	2	100	2	GO:0031691
GeneOntologyMolecularFunction	follicle-stimulating hormone receptor binding	ARRB1 ARRB2	7.42e-05	3	100	2	GO:0031762
GeneOntologyMolecularFunction	alpha-1B adrenergic receptor binding	ARRB1 ARRB2	7.42e-05	3	100	2	GO:0031692
GeneOntologyMolecularFunction	cytoskeletal protein binding	FLNB XIRP1 MAP1B AXL KIF1B ADD1 KIF20A SETD2 SAG MAP1S SVIL PHACTR4 STAU2 SCN5A SSH2 MTUS2	1.09e-04	1099	100	16	GO:0008092
GeneOntologyMolecularFunction	transmembrane transporter binding	DPP10 KCNB2 ITPR2 ARRB1 SCN5A KCNQ1	2.29e-04	172	100	6	GO:0044325
GeneOntologyMolecularFunction	phospholipid binding	MAPKAP1 MAP1B AXL PCLO TOM1L1 C2CD5 ITPR2 SVIL KCNQ1 SNX1	4.23e-04	548	100	10	GO:0005543
GeneOntologyCellularComponent	retromer complex	MAGEL2 DENND4C SNX1	1.33e-04	21	100	3	GO:0030904
GeneOntologyCellularComponent	costamere	ILK CMYA5 SVIL	1.53e-04	22	100	3	GO:0043034
GeneOntologyCellularComponent	dendrite	CACNA1B ILK MAP1B PCLO KIF1B KCNB2 ADD1 ARRB1 ARRB2 MAP1S PRKAA2 STAU2 SNX1	2.25e-04	858	100	13	GO:0030425
GeneOntologyCellularComponent	somatodendritic compartment	CACNA1B FLNB ILK MAP1B PCLO KIF1B KCNB2 ADD1 ARRB1 ARRB2 MAP1S PRKAA2 STAU2 KCNQ1 SNX1 SOS1	2.29e-04	1228	100	16	GO:0036477
GeneOntologyCellularComponent	dendritic tree	CACNA1B ILK MAP1B PCLO KIF1B KCNB2 ADD1 ARRB1 ARRB2 MAP1S PRKAA2 STAU2 SNX1	2.30e-04	860	100	13	GO:0097447
GeneOntologyCellularComponent	microtubule minus-end	SVIL ASPM	4.68e-04	7	100	2	GO:0036449
GeneOntologyCellularComponent	supramolecular fiber	FLNB ILK MAP1B KIF1B NCKAP5 CMYA5 KIF20A MAP1S SVIL STAU2 SCN5A ASPM AKAP13 MTUS2 NPNT	4.72e-04	1179	100	15	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	FLNB ILK MAP1B KIF1B NCKAP5 CMYA5 KIF20A MAP1S SVIL STAU2 SCN5A ASPM AKAP13 MTUS2 NPNT	5.06e-04	1187	100	15	GO:0099081
GeneOntologyCellularComponent	microtubule end	NCKAP5 SVIL ASPM	7.94e-04	38	100	3	GO:1990752
GeneOntologyCellularComponent	microtubule	MAP1B KIF1B NCKAP5 KIF20A MAP1S SVIL STAU2 ASPM MTUS2	1.04e-03	533	100	9	GO:0005874
GeneOntologyCellularComponent	centriole	KIAA0586 ARMC9 POC5 MPHOSPH9 HERC2	1.43e-03	172	100	5	GO:0005814
GeneOntologyCellularComponent	beta-catenin-TCF complex	BCL9 PYGO2	1.71e-03	13	100	2	GO:1990907
MousePheno	abnormal extracellular matrix morphology	FLNB XIRP1 ILK CMYA5 AKAP13 SOS1	3.41e-05	100	86	6	MP:0013258
MousePheno	abnormal muscle fiber morphology	XIRP1 MAGEL2 COL15A1 ANO5 CMYA5 USP19 MAP1S SCN5A BUB1B AKAP13 SOS1	3.74e-05	406	86	11	MP:0004087
Domain	Arrestin_N	SAG ARRB1 ARRB2	5.76e-07	4	99	3	IPR014753
Domain	Arrestin_CS	SAG ARRB1 ARRB2	5.76e-07	4	99	3	IPR017864
Domain	ARRESTINS	SAG ARRB1 ARRB2	5.76e-07	4	99	3	PS00295
Domain	Arrestin	SAG ARRB1 ARRB2	5.76e-07	4	99	3	IPR000698
Domain	-	SAG ARRB1 ARRB2	5.76e-07	4	99	3	2.60.40.840
Domain	-	SAG ARRB1 ARRB2	4.98e-06	7	99	3	2.60.40.640
Domain	Arrestin_C	SAG ARRB1 ARRB2	7.94e-06	8	99	3	IPR014752
Domain	Arrestin-like_N	SAG ARRB1 ARRB2	1.69e-05	10	99	3	IPR011021
Domain	Arrestin_C-like	SAG ARRB1 ARRB2	1.69e-05	10	99	3	IPR011022
Domain	Arrestin_C	SAG ARRB1 ARRB2	1.69e-05	10	99	3	SM01017
Domain	Arrestin_C	SAG ARRB1 ARRB2	1.69e-05	10	99	3	PF02752
Domain	Arrestin_N	SAG ARRB1 ARRB2	1.69e-05	10	99	3	PF00339
Domain	MAP1	MAP1B MAP1S	8.32e-05	3	99	2	IPR026074
Domain	Ion_trans_dom	CACNA1B KCNB2 ITPR2 SCN5A KCNQ1	3.51e-04	114	99	5	IPR005821
Domain	Ion_trans	CACNA1B KCNB2 ITPR2 SCN5A KCNQ1	3.51e-04	114	99	5	PF00520
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SFSWAP JADE3 KIF1B YTHDC2 CHD7 BCL9 USP19 ADD1 C2CD5 SETD2 EPS15L1 MAP1S SVIL PHACTR4 YY1AP1 SOS1	7.36e-10	774	100	16	15302935
Pubmed	Increased susceptibility to light damage in an arrestin knockout mouse model of Oguchi disease (stationary night blindness).	SAG ARRB1 ARRB2	2.31e-08	3	100	3	10549660
Pubmed	A family of retinal S-antigens (arrestins) and their genes: comparative analysis of human, mouse, rat, bovine and Drosophila.	SAG ARRB1 ARRB2	2.31e-08	3	100	3	1458825
Pubmed	Prolonged photoresponses in transgenic mouse rods lacking arrestin.	SAG ARRB1 ARRB2	2.31e-08	3	100	3	9333241
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAPKAP1 ILK MAP1B KIF1B DYRK4 TRIP11 DENND4C MAST4 SVIL PHACTR4 PRKAA2 BUB1B AKAP13 MPHOSPH9 SSH2	2.56e-08	861	100	15	36931259
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	FLNB MAP1B JADE3 BCORL1 DENND4C KIF20A EPS15L1 ARRB2 BUB1B MPHOSPH9 MED23 CABIN1 SNX1	4.42e-08	645	100	13	25281560
Pubmed	Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin.	SAG ARRB1 ARRB2	9.21e-08	4	100	3	10508404
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	JADE3 MAP4K3 VPS13C KIF1B LONP1 EPS15L1 MAST4 SVIL PHACTR4 BUB1B TNRC6A POC5 MPHOSPH9 HERC2	1.61e-07	853	100	14	28718761
Pubmed	A human MAP kinase interactome.	MAP4K3 TOM1L1 NCKAP5 ARRB1 ARRB2 TNRC6A AKAP13 YY1AP1 MPHOSPH9 HERC2 SOS1	1.64e-07	486	100	11	20936779
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	KIAA0586 PFAS YTHDC2 DENND4C ADD1 MAST4 STAU2 TNRC6A	1.72e-07	209	100	8	36779422
Pubmed	Dopamine receptor D4 internalization requires a beta-arrestin and a visual arrestin.	SAG ARRB1 ARRB2	2.30e-07	5	100	3	26169958
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SFSWAP VPS13C KIF1B MUC16 TRIP11 USP19 ADD1 KIF20A EPS15L1 PHACTR4 TNRC6A MPHOSPH9 SNX1	3.73e-07	777	100	13	35844135
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	MAP1B PFAS YTHDC2 ZNF395 DENND4C KIF20A MAP1S AKAP13	3.82e-07	232	100	8	25515538
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	XIRP1 ILK MAP1B BCORL1 PFAS KIF20A LONP1 EPS15L1 SVIL AKAP13 POC5 SSH2	7.12e-07	689	100	12	36543142
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLNB VPS39 KIF1B NCKAP5 CMYA5 TRIP11 EPS15L1 ARRB1 MAP1S YY1AP1 HERC2 CABIN1 MPPED2 MTUS2 SNX1 SOS1	7.97e-07	1285	100	16	35914814
Pubmed	Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.	BCL9 AXIN2 PYGO2	8.01e-07	7	100	3	30366904
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	ILK MAP1B JADE3 MAP4K3 AXL PRX C2CD5 AXIN2 ITPR2 MAP1S PRKAA2 BUB1B SOS1	2.16e-06	910	100	13	36736316
Pubmed	LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.	ITPR2 PRKAA2 SCN5A KCNQ1	2.79e-06	34	100	4	26378152
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNB MAP1B MAP4K3 PCLO KIF1B YTHDC2 TRIP11 ADD1 LRCH3 ITPR2 LONP1 EPS15L1 MAP1S SVIL SSH2 MTUS2	3.20e-06	1431	100	16	37142655
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VPS39 PFAS ZNF395 BCL9 ITPR2 HIVEP3 EPS15L1 MAP1S SCN5A AKAP13 HERC2 ZC3H7B CABIN1 CYB5R2	3.43e-06	1105	100	14	35748872
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	MAPKAP1 MAP4K3 TRIP11 ADD1 C2CD5 LRCH3 ARRB2 PHACTR4 SNX1	3.69e-06	421	100	9	36976175
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	TOM1L1 CLEC1A ANO5 CMYA5 TRIP11 DENND4C LRCH3 PHACTR4 PRKAA2 MANSC4 POC5	4.69e-06	686	100	11	29987050
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	VPS39 YTHDC2 C2CD5 LRCH3 ITPR2 KIF20A SETD2 HERC2 MED23	5.27e-06	440	100	9	34244565
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	MAP4K3 VPS39 VPS13C EI24 DENND4C C2CD5 EPS15L1 PHACTR4 STAU2 TNRC6A HERC2	7.30e-06	719	100	11	35337019
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIF1B BCORL1 PFAS CHD7 PGAM2 TRIP11 SETD2 TNRC6A ASPM YY1AP1	7.83e-06	588	100	10	38580884
Pubmed	Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2.	ARRB1 ARRB2	8.18e-06	2	100	2	18703513
Pubmed	Beta-arrestins 1 and 2 are associated with nicotine dependence in European American smokers.	ARRB1 ARRB2	8.18e-06	2	100	2	17579607
Pubmed	Comparative analysis of transcriptional profiles between two apoptotic pathways of light-induced retinal degeneration.	SAG ARRB1	8.18e-06	2	100	2	15541899
Pubmed	Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function.	ARRB1 ARRB2	8.18e-06	2	100	2	28973019
Pubmed	β-Arrestin1 enhances hepatocellular carcinogenesis through inflammation-mediated Akt signalling.	ARRB1 ARRB2	8.18e-06	2	100	2	26077142
Pubmed	Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.	ARRB1 ARRB2	8.18e-06	2	100	2	17426148
Pubmed	β-Arrestin-dependent ERK signaling reduces anxiety-like and conditioned fear-related behaviors in mice.	ARRB1 ARRB2	8.18e-06	2	100	2	34344831
Pubmed	Beta-arrestin-1 protein represses diet-induced obesity.	ARRB1 ARRB2	8.18e-06	2	100	2	21543334
Pubmed	LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1.	ARRB1 ARRB2	8.18e-06	2	100	2	34480046
Pubmed	ARRB2 (β-Arrestin-2) Deficiency Alters Fluid Homeostasis and Blood Pressure Regulation.	ARRB1 ARRB2	8.18e-06	2	100	2	36215165
Pubmed	Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1.	ARRB1 ARRB2	8.18e-06	2	100	2	17618287
Pubmed	Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function.	ARRB1 ARRB2	8.18e-06	2	100	2	26103985
Pubmed	β-Arrestin 1 and 2 similarly influence μ-opioid receptor mobility and distinctly modulate adenylyl cyclase activity.	ARRB1 ARRB2	8.18e-06	2	100	2	34450275
Pubmed	Biological Role of Arrestin-1 Oligomerization.	SAG ARRB1	8.18e-06	2	100	2	32948676
Pubmed	G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization.	ARRB1 ARRB2	8.18e-06	2	100	2	9668034
Pubmed	Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.	ARRB1 ARRB2	8.18e-06	2	100	2	31622341
Pubmed	Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors.	ARRB1 ARRB2	8.18e-06	2	100	2	16181421
Pubmed	Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians.	SCN5A KCNQ1	8.18e-06	2	100	2	17544529
Pubmed	Developmental changes in cardiac expression of KCNQ1 and SCN5A spliceoforms: Implications for sudden unexpected infant death.	SCN5A KCNQ1	8.18e-06	2	100	2	34843966
Pubmed	Genetic mutation in Korean patients of sudden cardiac arrest as a surrogating marker of idiopathic ventricular arrhythmia.	SCN5A KCNQ1	8.18e-06	2	100	2	23853484
Pubmed	Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.	ARRB1 ARRB2	8.18e-06	2	100	2	21855149
Pubmed	Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.	ARRB1 ARRB2	8.18e-06	2	100	2	18519945
Pubmed	Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts.	ARRB1 ARRB2	8.18e-06	2	100	2	26449263
Pubmed	The role of beta-arrestins in the formyl peptide receptor-like 1 internalization and signaling.	ARRB1 ARRB2	8.18e-06	2	100	2	17594911
Pubmed	Light-dependent regulation of the transcriptional activity of the mammalian gene for arrestin.	ARRB1 ARRB2	8.18e-06	2	100	2	7932878
Pubmed	Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference.	ARRB1 ARRB2	8.18e-06	2	100	2	12582207
Pubmed	Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling.	ARRB1 ARRB2	8.18e-06	2	100	2	26927499
Pubmed	β-Arrestin prevents cell apoptosis through pro-apoptotic ERK1/2 and p38 MAPKs and anti-apoptotic Akt pathways.	ARRB1 ARRB2	8.18e-06	2	100	2	22699970
Pubmed	beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.	ARRB1 ARRB2	8.18e-06	2	100	2	19349687
Pubmed	β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix.	ARRB1 ARRB2	8.18e-06	2	100	2	21411739
Pubmed	Results of genetic testing in 855 consecutive unrelated patients referred for long QT syndrome in a clinical laboratory.	SCN5A KCNQ1	8.18e-06	2	100	2	23631430
Pubmed	The Two β-Arrestins Regulate Distinct Metabolic Processes: Studies with Novel Mutant Mouse Models.	ARRB1 ARRB2	8.18e-06	2	100	2	35008921
Pubmed	Deficiency of β-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.	ARRB1 ARRB2	8.18e-06	2	100	2	30541881
Pubmed	β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling.	ARRB1 ARRB2	8.18e-06	2	100	2	25134464
Pubmed	beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking.	ARRB1 ARRB2	8.18e-06	2	100	2	11171997
Pubmed	Regulation of lipopolysaccharide-induced inflammatory response and endotoxemia by beta-arrestins.	ARRB1 ARRB2	8.18e-06	2	100	2	20589830
Pubmed	Control of rhodopsin's active lifetime by arrestin-1 expression in mammalian rods.	SAG ARRB1	8.18e-06	2	100	2	20203204
Pubmed	β-Arrestin2 mediates the initiation and progression of myeloid leukemia.	ARRB1 ARRB2	8.18e-06	2	100	2	22773819
Pubmed	Staufen 2 regulates mGluR long-term depression and Map1b mRNA distribution in hippocampal neurons.	MAP1B STAU2	8.18e-06	2	100	2	21508097
Pubmed	Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.	ARRB1 ARRB2	8.18e-06	2	100	2	17418896
Pubmed	β-Arrestin2 mediates progression of murine primary myelofibrosis.	ARRB1 ARRB2	8.18e-06	2	100	2	29263312
Pubmed	β-Arrestins Regulate Stem Cell-Like Phenotype and Response to Chemotherapy in Bladder Cancer.	ARRB1 ARRB2	8.18e-06	2	100	2	30787175
Pubmed	beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.	ARRB1 ARRB2	8.18e-06	2	100	2	19896992
Pubmed	Functional comparisons of visual arrestins in rod photoreceptors of transgenic mice.	SAG ARRB1	8.18e-06	2	100	2	17460248
Pubmed	Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers.	ARRB1 ARRB2	8.18e-06	2	100	2	29330504
Pubmed	Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants.	SAG ARRB1	8.18e-06	2	100	2	16421323
Pubmed	Histone methyltransferase SETD2 is required for meiotic maturation in mouse oocyte.	SETD2 BUB1B	8.18e-06	2	100	2	30078214
Pubmed	β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.	ARRB1 ARRB2	8.18e-06	2	100	2	27054338
Pubmed	Transduction of group I mGluR-mediated synaptic plasticity by β-arrestin2 signalling.	ARRB1 ARRB2	8.18e-06	2	100	2	27886171
Pubmed	Hepatic β-arrestin 2 is essential for maintaining euglycemia.	ARRB1 ARRB2	8.18e-06	2	100	2	28650340
Pubmed	Molecular analysis of human beta-arrestin-1: cloning, tissue distribution, and regulation of expression. Identification of two isoforms generated by alternative splicing.	ARRB1 ARRB2	8.18e-06	2	100	2	8486659
Pubmed	Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade.	ARRB1 ARRB2	8.18e-06	2	100	2	34507982
Pubmed	β-arrestin expression in corticotroph tumor cells is modulated by glucocorticoids.	ARRB1 ARRB2	8.18e-06	2	100	2	32027601
Pubmed	Mutation analysis in congenital Long QT Syndrome--a case with missense mutations in KCNQ1 and SCN5A.	SCN5A KCNQ1	8.18e-06	2	100	2	12820704
Pubmed	β-arrestins negatively control human adrenomedullin type 1-receptor internalization.	ARRB1 ARRB2	8.18e-06	2	100	2	28427767
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	VPS13C EI24 CHD7 DENND4C ADD1 ITPR2 SETD2 TNRC6A AKAP13 POC5 MPHOSPH9	8.75e-06	733	100	11	34672954
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	FLNB DENND4C KIF20A EPS15L1 BUB1B ASPM SNX1	9.64e-06	256	100	7	33397691
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	MAPKAP1 AXL TOM1L1 KIAA0586 PFAS USP19 EPS15L1 PRKAA2 HERC2 MTUS2	9.88e-06	604	100	10	38803224
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	TOM1L1 NCKAP5 BRDT BUB1B GAPDHS	1.43e-05	106	100	5	18654987
Pubmed	Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.	TOM1L1 EPS15L1 PHACTR4 BUB1B SOS1	1.71e-05	110	100	5	37219487
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MAPKAP1 MAP1B EI24 PFAS YTHDC2 BUB1B AKAP13 YY1AP1 GAPDHS ZC3H7B	1.86e-05	650	100	10	38777146
Pubmed	Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.	FEZF1 LHX5 MPPED2 FGF19	2.11e-05	56	100	4	34170322
Pubmed	Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.	ARRB1 ARRB2	2.45e-05	3	100	2	18787115
Pubmed	Variant frequencies of KCNQ1, KCNH2, and SCN5A in a Chinese inherited arrhythmia cohort and other disease cohorts undergoing genetic testing.	SCN5A KCNQ1	2.45e-05	3	100	2	31696929
Pubmed	Molecular properties of rhodopsin and rod function.	SAG ARRB1	2.45e-05	3	100	2	17194706
Pubmed	Pygopus residues required for its binding to Legless are critical for transcription and development.	BCL9 PYGO2	2.45e-05	3	100	2	14612447
Pubmed	Identification of receptor binding-induced conformational changes in non-visual arrestins.	ARRB1 ARRB2	2.45e-05	3	100	2	24867953
Pubmed	The prevalence of mutations in KCNQ1, KCNH2, and SCN5A in an unselected national cohort of young sudden unexplained death cases.	SCN5A KCNQ1	2.45e-05	3	100	2	22882672
Pubmed	β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells.	ARRB1 ARRB2	2.45e-05	3	100	2	26211463
Pubmed	Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes.	SCN5A KCNQ1	2.45e-05	3	100	2	17161064
Pubmed	β-Arrestin signal complex plays a critical role in adipose differentiation.	ARRB1 ARRB2	2.45e-05	3	100	2	23557604
Pubmed	Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes.	SAG ARRB2	2.45e-05	3	100	2	7695743
Pubmed	Beta-blocker therapy failures in symptomatic probands with genotyped long-QT syndrome.	SCN5A KCNQ1	2.45e-05	3	100	2	15534720
Pubmed	Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers.	SCN5A KCNQ1	2.45e-05	3	100	2	15367556
Pubmed	Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.	SCN5A KCNQ1	2.45e-05	3	100	2	11136691
Interaction	CALM3 interactions	FLNB AXL VPS13C KIF1B DENND4C LRCH3 ITPR2 ARRB1 ARRB2 SVIL ASPM POC5	1.20e-07	343	99	12	int:CALM3
Interaction	MED4 interactions	FLNB MAP1B TRIP11 DENND4C EPS15L1 ARRB2 BUB1B TNRC6A POC5 MPHOSPH9 HERC2 MED23 SNX1	3.12e-07	450	99	13	int:MED4
Interaction	ZYX interactions	KIAA0586 ARRB1 SVIL BUB1B TNRC6A AKAP13 POC5 MPHOSPH9 SSH2 ZC3H7B	5.05e-06	329	99	10	int:ZYX
Interaction	TRIP13 interactions	MAP1B AXL KIF20A M1AP PRKAA2 BUB1B TNRC6A MPPED2 CYB5R2	1.01e-05	281	99	9	int:TRIP13
Interaction	CALM1 interactions	VPS13C KIF1B DENND4C ADD1 LRCH3 KIF20A SVIL PHACTR4 SCN5A ASPM POC5 HERC2 CABIN1	1.18e-05	626	99	13	int:CALM1
Interaction	SAG interactions	SAG ARRB1 ARRB2	1.35e-05	10	99	3	int:SAG
Interaction	GSK3B interactions	ILK MAP1B KIAA0586 PFAS YTHDC2 DENND4C ADD1 AXIN2 ARRB1 ARRB2 MAST4 PRKAA2 STAU2 TNRC6A HERC2	2.12e-05	868	99	15	int:GSK3B
Interaction	ARRDC4 interactions	MAP1B ARRB1 ARRB2 SVIL HERC2	5.54e-05	83	99	5	int:ARRDC4
Interaction	CSK interactions	ILK TOM1L1 CLEC1A ANO5 CMYA5 TRIP11 DENND4C LRCH3 ARRB1 ARRB2 PHACTR4 PRKAA2 MANSC4 POC5	7.89e-05	861	99	14	int:CSK
Interaction	TNFRSF1B interactions	C2CD5 HIVEP3 ARRB1 ARRB2 STAU2 POC5	8.40e-05	146	99	6	int:TNFRSF1B
Interaction	GSK3A interactions	KIAA0586 PFAS YTHDC2 DENND4C ADD1 AXIN2 ARRB2 MAST4 STAU2 TNRC6A	9.50e-05	464	99	10	int:GSK3A
GeneFamily	Classical arrestins	SAG ARRB1 ARRB2	1.46e-07	4	61	3	1312
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000	MAGEL2 MAP1B JADE3 PCLO KIF1B KIAA0586 NCKAP5 CHD7 PGAM2 HIVEP3 FEZF1 STAU2 ASPM LHX5 MPPED2 FGF19	1.09e-05	986	98	16	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	ANO5 NCKAP5 CMYA5 MAST4 SVIL PRKAA2 SCN5A AKAP13 MTUS2	6.07e-10	195	100	9	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	NCKAP5 CMYA5 MAST4 SVIL PRKAA2 SCN5A AKAP13 MTUS2	1.17e-08	190	100	8	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ANO5 NCKAP5 CMYA5 MAST4 SVIL PRKAA2 SCN5A MTUS2	1.32e-08	193	100	8	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 ANO5 CMYA5 PRKAA2 SCN5A FGF19 MTUS2	1.16e-07	170	100	7	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	XIRP1 NCKAP5 CMYA5 MAST4 SVIL PRKAA2 MTUS2	1.84e-07	182	100	7	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 ANO5 CMYA5 SVIL PRKAA2 SCN5A MTUS2	2.06e-07	185	100	7	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	facs-Heart-Unknown-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PLIN5 PRKAA2 SCN5A MTUS2	2.21e-07	187	100	7	0ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ANO5 CMYA5 MAST4 SVIL PRKAA2 AKAP13 MTUS2	2.55e-07	191	100	7	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	NCKAP5 CMYA5 MAST4 SVIL PRKAA2 SCN5A MTUS2	2.55e-07	191	100	7	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ANO5 NCKAP5 CMYA5 MAST4 SVIL PRKAA2 MTUS2	2.64e-07	192	100	7	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	NCKAP5 CMYA5 MAST4 SVIL PRKAA2 SCN5A MTUS2	2.84e-07	194	100	7	c3535f7cc0076653c72db582047cff053c322397
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	ANO5 NCKAP5 CMYA5 SVIL PRKAA2 SCN5A MTUS2	2.94e-07	195	100	7	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 TOM1L1 CMYA5 PGAM2 KCNQ1 MTUS2	2.37e-06	170	100	6	d99f61aa85ea3f775165cb433421e6f1cda4f96b
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 TOM1L1 CMYA5 PGAM2 KCNQ1 MTUS2	2.37e-06	170	100	6	615cf9639c66b3fbd984ebe3f345280005d3c38a
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 ANO5 CMYA5 PRKAA2 SCN5A MTUS2	3.40e-06	181	100	6	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	XIRP1 CMYA5 MAST4 SVIL PRKAA2 AKAP13	3.74e-06	184	100	6	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	facs-Heart-Unknown\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PLIN5 SCN5A MTUS2	4.10e-06	187	100	6	362e56426a568423a81e8a30e3ecf99b76135843
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	ANO5 NCKAP5 CMYA5 PRKAA2 SCN5A MTUS2	4.10e-06	187	100	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	facs-Heart-Unknown-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PLIN5 SCN5A MTUS2	4.10e-06	187	100	6	c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 KCNQ1 MTUS2	4.23e-06	188	100	6	90dc0e15798d0b984518ad58c7e416e30aff687a
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PLIN5 PRKAA2 SCN5A	4.23e-06	188	100	6	4db566f3f708e66730aa9e16f4d73d91dc534177
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 KCNQ1 MTUS2	4.23e-06	188	100	6	f63dfd076ced81013918363282ae25cbbd8948ae
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 KCNQ1 MTUS2	4.23e-06	188	100	6	0554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PLIN5 PRKAA2 SCN5A	4.23e-06	188	100	6	6704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	ANO5 NCKAP5 CMYA5 PRKAA2 SCN5A MTUS2	4.36e-06	189	100	6	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CMYA5 MAST4 SVIL PRKAA2 AKAP13 MTUS2	4.36e-06	189	100	6	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	facs-Heart-LA/RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 KCNQ1 MTUS2	4.36e-06	189	100	6	a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCell	facs-Heart-LA/RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 KCNQ1 MTUS2	4.36e-06	189	100	6	efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	XIRP1 NCKAP5 CMYA5 MAST4 SVIL AKAP13	4.36e-06	189	100	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	XIRP1 NCKAP5 CMYA5 MAST4 SVIL AKAP13	4.49e-06	190	100	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ANO5 CMYA5 MAST4 PRKAA2 AKAP13 MTUS2	4.49e-06	190	100	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 COL15A1 MAP1B CMYA5 SCN5A MTUS2	4.49e-06	190	100	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 ANO5 CMYA5 PGAM2 PLIN5 SCN5A	4.63e-06	191	100	6	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 SCN5A MTUS2	4.63e-06	191	100	6	c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 ANO5 CMYA5 PGAM2 PLIN5 SCN5A	4.63e-06	191	100	6	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 SCN5A MTUS2	4.63e-06	191	100	6	715f5b449b8e075959c05a5b38389df319663164
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	NCKAP5 MAST4 SVIL TNRC6A AKAP13 SSH2	4.77e-06	192	100	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ILK MAP1B SVIL PRKAA2 MPPED2 NPNT	5.06e-06	194	100	6	93bc72a933ccc6a760e5353f072afb606571c6fc
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NCKAP5 CMYA5 MAST4 SVIL PRKAA2 MTUS2	5.06e-06	194	100	6	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	JADE3 ARRB1 FCRL3 PNPLA1 BRDT BUB1B	5.22e-06	195	100	6	dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 SCN5A MTUS2	5.37e-06	196	100	6	a582130862bee76c0385156a333bfdfc75cf218b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 SCN5A MTUS2	5.37e-06	196	100	6	fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCLO TOM1L1 MAST4 PRKAA2 KCNQ1 MPPED2	5.37e-06	196	100	6	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	TOM1L1 ARMC9 KIF20A M1AP SAG ASPM	5.86e-06	199	100	6	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	BLNK NCKAP5 ITPR2 HIVEP3 ARRB2 AKAP13	6.03e-06	200	100	6	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	BLNK NCKAP5 ITPR2 HIVEP3 ARRB2 AKAP13	6.03e-06	200	100	6	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	BLNK NCKAP5 ITPR2 HIVEP3 ARRB2 AKAP13	6.03e-06	200	100	6	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	BLNK NCKAP5 ITPR2 HIVEP3 ARRB2 AKAP13	6.03e-06	200	100	6	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	BLNK NCKAP5 ITPR2 HIVEP3 ARRB2 AKAP13	6.03e-06	200	100	6	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	BLNK NCKAP5 ITPR2 HIVEP3 ARRB2 AKAP13	6.03e-06	200	100	6	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	Club-club-1\|World / Class top	VPS13C PFAS YTHDC2 GDPD4	6.67e-06	54	100	4	48f80b20b1c4995a0f7084d31666781dce4009a9
ToppCell	facs-Heart-RA-24m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGEL2 CMYA5 PGAM2 SCN5A MTUS2	2.80e-05	157	100	5	9021900d9b1a71210c9c414a9d165eaf399eb607
ToppCell	facs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGEL2 CMYA5 PGAM2 SCN5A MTUS2	2.80e-05	157	100	5	c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1B DPP10 KCNB2 PGAM2 MTUS2	3.76e-05	167	100	5	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1B DPP10 PCLO KCNB2 PGAM2	4.09e-05	170	100	5	6a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 DYRK4 CMYA5 ITPR2 MAST4	4.09e-05	170	100	5	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL BLNK ZNF395 ARRB2 PNPLA1	4.45e-05	173	100	5	26bba58f9fb215d1d155504906cd77e8774f6936
ToppCell	droplet-Lung-LUNG-1m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL BLNK ZNF395 ARRB2 PNPLA1	4.45e-05	173	100	5	69b404e92aad3e6dff67e75466f073f20a71f13f
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	CACNA1B ANO5 KCNB2 SCN5A GAPDHS	4.70e-05	175	100	5	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DPP10 BLNK NCKAP5 ITPR2 MTUS2	4.70e-05	175	100	5	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1B ANO5 KCNB2 SCN5A GAPDHS	4.70e-05	175	100	5	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNB2 KIF20A BUB1B OSR1 ASPM	4.82e-05	176	100	5	75412d58438d71c49a6096bb2ef12b7f349653d8
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 CMYA5 PRKAA2 SCN5A MTUS2	4.82e-05	176	100	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	facs-Heart-RV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PLIN5 MTUS2	4.96e-05	177	100	5	692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCell	facs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PLIN5 MTUS2	4.96e-05	177	100	5	c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARMC9 SVIL OSR1 MPPED2 MTUS2	5.09e-05	178	100	5	0fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	COL15A1 MAP1B SVIL OSR1 MTUS2	5.37e-05	180	100	5	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL15A1 SVIL SCN5A LHX5 NPNT	5.51e-05	181	100	5	153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B PCLO CHD7 PGAM2 SCN5A	5.51e-05	181	100	5	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CACNA1B DPP10 PCLO ANO5 KCNB2	5.66e-05	182	100	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB C11orf16 PGAM2 KCNQ1 MPPED2	5.66e-05	182	100	5	75608f80fd570da499891dc02f8649d5428b896c
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PFAS KIF20A SVIL BUB1B ASPM	5.66e-05	182	100	5	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PFAS KIF20A SVIL BUB1B ASPM	5.66e-05	182	100	5	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PFAS KIF20A SVIL BUB1B ASPM	5.66e-05	182	100	5	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	MAP1B BCORL1 PFAS OSR1 MTUS2	5.66e-05	182	100	5	ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 MAP1B ANO5 CMYA5 PRKAA2	5.80e-05	183	100	5	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BEST1 AXL KIF20A BUB1B ASPM	5.80e-05	183	100	5	e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL15A1 JADE3 AXL KCNB2 OSR1	5.80e-05	183	100	5	07ca2786e62eca9feecf5e54a11864a960f7641a
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CACNA1B DPP10 PCLO PGAM2 MTUS2	5.96e-05	184	100	5	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ILK MAP1B SVIL OSR1 NPNT	5.96e-05	184	100	5	5cfc19ffb9f074bdf0d81c86e212a708ec141631
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANO5 CMYA5 PRKAA2 SCN5A MTUS2	5.96e-05	184	100	5	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL PCLO KIF20A BUB1B ASPM	5.96e-05	184	100	5	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PLIN5 SCN5A MTUS2	6.27e-05	186	100	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	ITPR2 PHACTR4 KCNQ1 MPHOSPH9 NPNT	6.27e-05	186	100	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PLIN5 SCN5A MTUS2	6.27e-05	186	100	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ITPR2 PHACTR4 KCNQ1 MPHOSPH9 NPNT	6.27e-05	186	100	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1B DPP10 PCLO ANO5 KCNB2	6.27e-05	186	100	5	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAPKAP1 FLNB COL15A1 KCNQ1 MPHOSPH9	6.43e-05	187	100	5	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAPKAP1 FLNB COL15A1 KCNQ1 MPHOSPH9	6.43e-05	187	100	5	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	ANO5 CMYA5 MAST4 PRKAA2 MTUS2	6.59e-05	188	100	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1B DPP10 PCLO ANO5 KCNB2	6.59e-05	188	100	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	P07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	XIRP1 ILK MAP1B AXL OSR1	6.59e-05	188	100	5	6ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PRKAA2 SCN5A MTUS2	6.76e-05	189	100	5	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PRKAA2 SCN5A MTUS2	6.76e-05	189	100	5	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 COL15A1 AXL CMYA5 SCN5A	6.76e-05	189	100	5	2a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCell	droplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 MTUS2	7.11e-05	191	100	5	97fb4232417a39801e87725755fd16a57c250209
ToppCell	droplet-Heart-nan-3m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 CMYA5 PGAM2 PRKAA2 MTUS2	7.11e-05	191	100	5	64070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMYA5 PGAM2 PRKAA2 KCNQ1 MTUS2	7.28e-05	192	100	5	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B PCLO CHD7 KCNB2 PGAM2	7.28e-05	192	100	5	fe9297cb65234d9f511bab1a5dbf2679d5a4cd15
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	PCLO ARMC9 MAST4 PLIN5 NPNT	7.28e-05	192	100	5	06013a07e3a873b1d1c0451643c528593ac32a9c
Drug	2,2,2-trifluoroethanethiol	SAG ARRB1 ARRB2	8.17e-07	5	100	3	CID004133924
Drug	sulfo-SADP	SAG ARRB1 ARRB2	2.84e-06	7	100	3	CID000128116
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	MAP4K3 CHD7 MAST4 SVIL BUB1B AKAP13 MPPED2	1.19e-05	174	100	7	7530_DN
Drug	aluminum(III) chloride	SAG ARRB1 ARRB2	1.32e-05	11	100	3	CID006451240
Drug	ddeCyd	SAG ARRB1 ARRB2	1.76e-05	12	100	3	CID000064683
Drug	Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A	ILK SFSWAP KIF20A SETD2 EPS15L1 BUB1B ASPM	2.25e-05	192	100	7	1599_DN
Drug	Lovastatin [75330-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A	PCLO BLNK ADD1 EPS15L1 SAG ARRB1 CABIN1	2.32e-05	193	100	7	4978_UP
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A	VPS39 VPS13C ADD1 LRCH3 KIF20A SETD2 MPHOSPH9	2.56e-05	196	100	7	2005_DN
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; HL60; HG-U133A	DYRK4 HIVEP3 SVIL STAU2 AKAP13 MPHOSPH9 CABIN1	2.83e-05	199	100	7	1391_DN
Drug	Benzocaine [94-09-7]; Up 200; 24.2uM; HL60; HT_HG-U133A	JADE3 YTHDC2 AKR1C4 C11orf16 PGAM2 TRIP11 ZC3H7B	2.92e-05	200	100	7	2167_UP
Drug	CTK8F0943	BLNK AKR1C4 ADD1	4.42e-05	16	100	3	CID010062692
Disease	Idiopathic hypogonadotropic hypogonadism	AXL CHD7 FEZF1	2.88e-05	18	99	3	C0342384
Disease	neutrophil count	FLNB KIF1B BCORL1 CHD7 BCL9 ITPR2 HIVEP3 SETD2 EPS15L1 TNRC6A AKAP13 YY1AP1 POC5 SSH2 FGF19	5.64e-05	1382	99	15	EFO_0004833
Disease	Paroxysmal familial ventricular fibrillation	SCN5A KCNQ1	6.66e-05	4	99	2	C0340493
Disease	body weight	CACNA1B VPS13C TOM1L1 ANO5 CHD7 KCNB2 AXIN2 SETD2 MAST4 FEZF1 TNRC6A KCNQ1 POC5 MPPED2	8.05e-05	1261	99	14	EFO_0004338
Disease	long QT syndrome (is_implicated_in)	SCN5A KCNQ1	2.31e-04	7	99	2	DOID:2843 (is_implicated_in)
Disease	Embryonal Rhabdomyosarcoma	SETD2 BUB1B	3.08e-04	8	99	2	C0206656
Disease	lymphocyte count	FLNB PCDHGC5 KIF1B CHD7 AKR1C4 ZNF395 ITPR2 SETD2 EPS15L1 SAG ARRB2 PRKAA2 SSH2 ZC3H7B	3.76e-04	1464	99	14	EFO_0004587
Disease	electrocardiography	AXL YTHDC2 ARMC9 MAST4 SVIL SCN5A KCNQ1 MANSC4	4.21e-04	530	99	8	EFO_0004327
Disease	cholesteryl ester 20:5 measurement	BEST1 DPP10 SVIL	4.39e-04	44	99	3	EFO_0010349
Disease	Gastric Adenocarcinoma	AXL BRDT PRKAA2	4.69e-04	45	99	3	C0278701
Disease	PRADER-WILLI SYNDROME	MAGEL2 HERC2	4.93e-04	10	99	2	176270
Disease	Prader-Willi syndrome	MAGEL2 HERC2	4.93e-04	10	99	2	cv:C0032897
Disease	age at onset, multiple sclerosis	NCKAP5 KCNB2	4.93e-04	10	99	2	EFO_0004847, MONDO_0005301
Disease	selective IgA deficiency disease	NCKAP5 FCRL3 MAST4	5.01e-04	46	99	3	EFO_1001929
Disease	comparative body size at age 10, self-reported	TRIP11 EPS15L1 MAST4 TNRC6A POC5 ZC3H7B FGF19	5.45e-04	420	99	7	EFO_0009819
Disease	multiple myeloma	ANO5 ARMC9 HERC2 SOS1	5.61e-04	112	99	4	EFO_0001378
Disease	HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA	AXL FEZF1	6.01e-04	11	99	2	146110
Disease	Hypogonadotropic hypogonadism 7 with or without anosmia	AXL FEZF1	6.01e-04	11	99	2	cv:C0342384
Disease	Congenital long QT syndrome	SCN5A KCNQ1	6.01e-04	11	99	2	cv:C1141890
Disease	Long QT Syndrome	SCN5A KCNQ1	6.01e-04	11	99	2	C0023976
Disease	Royer Syndrome	MAGEL2 HERC2	7.20e-04	12	99	2	C0265222
Disease	Long QT syndrome	SCN5A KCNQ1	7.20e-04	12	99	2	cv:C0023976
Disease	monocyte percentage of leukocytes	KIF1B ARMC9 CHD7 ADD1 SETD2 EPS15L1 MAP1S AKAP13 SSH2	7.97e-04	731	99	9	EFO_0007989
Disease	Prader-Willi Syndrome	MAGEL2 HERC2	8.48e-04	13	99	2	C0032897
Disease	T wave morphology measurement	SCN5A KCNQ1	9.88e-04	14	99	2	EFO_0008398
Disease	familial atrial fibrillation (is_implicated_in)	SCN5A KCNQ1	9.88e-04	14	99	2	DOID:0050650 (is_implicated_in)
Disease	neutrophil percentage of granulocytes	CHD7 HIVEP3 EPS15L1 AKAP13 ZC3H7B	1.05e-03	228	99	5	EFO_0007994
Disease	eosinophil percentage of granulocytes	CHD7 HIVEP3 EPS15L1 AKAP13 ZC3H7B	1.17e-03	234	99	5	EFO_0007996
Disease	myeloid white cell count	FLNB KIF1B CHD7 BCL9 PRX HIVEP3 SETD2 EPS15L1 SSH2 FGF19	1.21e-03	937	99	10	EFO_0007988
Disease	Romano-Ward Syndrome	SCN5A KCNQ1	1.30e-03	16	99	2	C0035828
Disease	anthranilic acid measurement	KIF1B KCNQ1	1.30e-03	16	99	2	EFO_0010460
Disease	response to acetylsalicylate	SETD2 KCNQ1	1.30e-03	16	99	2	GO_1903492
Disease	S-6-hydroxywarfarin measurement	DPP10 VPS13C PCLO TOM1L1 KCNB2 DENND4C	1.53e-03	368	99	6	EFO_0803326
Disease	photoreceptor cell layer thickness measurement	MAP1B CHD7 GDPD4 SAG	1.58e-03	148	99	4	EFO_0803370
Disease	Liver carcinoma	COL15A1 ADD1 AXIN2 KIF20A BUB1B ASPM FGF19	1.62e-03	507	99	7	C2239176
Disease	cortical surface area measurement	FLNB KIF1B NCKAP5 CHD7 MAST4 STAU2 TNRC6A MPHOSPH9 SSH2 MED23 MPPED2 SOS1	1.82e-03	1345	99	12	EFO_0010736
Disease	Disproportionate short stature	FLNB ANO5 TRIP11	2.24e-03	77	99	3	C0878659
Disease	Joubert syndrome 1	KIAA0586 ARMC9	2.24e-03	21	99	2	C4551568
Disease	ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)	SCN5A KCNQ1	2.46e-03	22	99	2	C1843687
Disease	Cardiomegaly	ITPR2 PRKAA2 CABIN1	2.68e-03	82	99	3	C0018800
Disease	Cardiac Hypertrophy	ITPR2 PRKAA2 CABIN1	2.68e-03	82	99	3	C1383860
Disease	neuroimaging measurement	MAP1B KIF1B NCKAP5 ARMC9 CHD7 DENND4C MAST4 TNRC6A SSH2 MPPED2	3.16e-03	1069	99	10	EFO_0004346

Protein segments in the cluster

Peptide	Gene	Start	Entry
PFHEIMSLKDLPSDP	BUB1B	621	O60566
LHFPMALKPGETPLP	AKR1C4	116	P17516
LSMPPPKFHDTSSPL	EPS15L1	96	Q9UBC2
PKFHDTSSPLMVTPP	EPS15L1	101	Q9UBC2
MPIKESDIPRPKHTP	ANO5	151	Q75V66
THFSKIPIEPVESMP	BRDT	371	Q58F21
HPERMPPLIADSPKA	PRKAA2	366	P54646
MPELPLLPHDSHPKE	BCORL1	1006	Q5H9F3
HPHPVVPKMEKELVP	AKAP13	761	Q12802
KEDVPFPLMAGPTVP	CLDN25	191	C9JDP6
HRLPKEMTPVEPATF	AXIN2	356	Q9Y2T1
PMFFPLEPSAPSKLH	BEST1	476	O76090
PFRLMHPQPEDPAKE	SAG	356	P10523
TLDLLVPPHKPDEMT	CACNA1B	1836	Q00975
HSPSEPFLEKPVPDM	CHD7	556	Q9P2D1
GPTHTLELMPPDSFK	DPP10	301	Q8N608
KPLKTDIPRHPMPFA	ASPM	671	Q8IZT6
ELPFTLMHPKPKEEP	ARRB1	346	P49407
LMHPKPKEEPPHREV	ARRB1	351	P49407
VSVELPFVLMHPKPH	ARRB2	336	P32121
PPTCTMPLPHEEKAA	MTUS2	671	Q5JR59
GFVTADMIKEHLPPP	CYB5R2	226	Q6BCY4
MSVPDVPPSIHPSKQ	ITPR2	941	Q14571
VHMVDPIPYDTPKPA	MPPED2	41	Q15777
IPSEMPTPPKTSHGE	MUC16	11946	Q8WXI7
PVLSPRKPSHPVMDF	POC5	106	Q8NA72
PPKPKSIFIPQEMHS	MAP4K3	436	Q8IVH8
KMLTVPHITCDPPEE	KCNQ1	436	P51787
PSIHVPSPAVPKLTM	LRCH3	701	Q96II8
KTVTYKHMDPPPAPV	MAP1B	2191	P46821
EHRKAVPMAPAPASP	MAP1S	746	Q66K74
MLPSTFPLLPEDPHD	M1AP	406	Q8TC57
KGQPPVPHEIPTSME	MAGEL2	591	Q9UJ55
IPKVMIEPSGPIHVP	NPNT	256	Q6UXI9
LTTPIMFPPEHPVEE	HERC2	1421	O95714
PLPPELLPTEMEKTH	KIF1B	801	O60333
LPFVPNPMVHPSFKE	ARMC9	151	Q7Z3E5
VHIPGSPFKADIEMP	FLNB	1116	O75369
VLHPDMAKVPPASPK	PCLO	3656	Q9Y6V0
PEEMPKSSDFLIHPP	PCDHGC5	671	Q9Y5F6
PLSHFLPMLPMVPEE	FGF19	161	O95750
FITHISKMEPAAVPP	MED23	1331	Q9ULK4
PPEVLTLDPTLHMKP	MPHOSPH9	286	Q99550
LSGMPPVSFPAVHKP	PNPLA1	366	Q8N8W4
FEPIDTKLSHMPVPP	MANSC4	236	A6NHS7
FTDMISHPDTPSPEP	LHX5	341	Q9H2C1
ALTPMTIPDVFPHLP	LONP1	111	P36776
PGKHEIQPPMPTVVF	GDPD4	571	Q6W3E5
TPSLTHMVPAKQPPI	PHACTR4	246	Q8IZ21
MGSKTLPAPVPIHPS	OSR1	1	Q8TAX0
SHLTEFAPPPTPMVD	PYGO2	56	Q9BRQ0
MPASELKASEIPFHP	DYRK4	1	Q9NR20
LPPPSASHLQMKFPT	KCNB2	621	Q92953
HPTESSSPPPEKAPM	BLNK	191	Q8WV28
PQVKMAPTSSPAEPH	CABIN1	2036	Q9Y6J0
PHPFPSVSKIIADML	EI24	161	O14681
IPPNHKAPLTMASPA	BCL9	946	O00512
LVSEKPFPPHMSPEV	CMYA5	541	Q8N3K9
PTIPPGISPHVCKLM	ILK	411	Q13418
QKSEHTVFIMPPEPP	DENND4C	681	Q5VZ89
DPQEPTHSKPLAPME	FCRL3	631	Q96P31
ELDHILSPPPMPFRK	MAST4	121	O15021
HPATPPPKMVSVARE	GAPDHS	61	O14556
IFPIPVRPHCKMPVD	COL15A1	956	P39059
PSHPFPPAKAMTVEK	C2CD5	836	Q86YS7
QPSPKKPDHPLMVSA	CFAP74	1546	Q9C0B2
PERMEPITKISHIPP	JADE3	291	Q92613
DVPIPMASTTHPEKP	FER1L6	546	Q2WGJ9
MLEPEHTPVAQEPPK	FER1L6	1166	Q2WGJ9
VPSDVELPPTAKMHA	SFSWAP	196	Q12872
LPPLPSNHPAMTKSD	TOM1L1	421	O75674
PPITHLGDEPKEFSM	SVIL	1006	O95425
PSVAFKKPIFTHPMP	NCKAP5	996	O14513
KKPIFTHPMPSPEAV	NCKAP5	1001	O14513
RRSFDIPPPPMDEKH	PGAM2	116	P15259
IMARTPEPKALPVPH	FEZF1	36	A0PJY2
PVMLEHPPDTTTPSE	SCN5A	621	Q14524
VDLEKIHPPSMPGDS	MAPKAP1	36	Q9BPZ7
IMSKHLDSPPAIPPR	SOS1	1171	Q07889
PMLEKEEEAHRPPSP	ADD1	656	P35611
AGMVKPESLHVPPET	CLEC1A	261	Q8NC01
LVSKATHMKPPRTPP	C11orf16	431	Q9NQ32
KHMKPSVEPAPPVSR	RNASEH1	116	O60930
ETHLASPKPTCMVPP	USP19	456	O94966
FIVPPPPEKSLIGMT	SNX1	206	Q13596
MPVSFEVIKESGPPH	STAU2	221	Q9NUL3
IAEVKTMESHPPIPP	SSH2	491	Q76I76
MLEPPPSAKPFTIDV	KIF20A	716	O95235
PKVPEMAVPDVHLPE	PRX	606	Q9BXM0
LPKVPEMAVPDVHLP	PRX	641	Q9BXM0
HPIQSFSPESMPEPL	PFAS	156	O15067
TPAFMSPGKPEHLLE	HIVEP3	101	Q5T1R4
PAPAMKSHLIVTSPP	ZNF395	456	Q9H8N7
ESFPAPVVILPFMKH	AXL	611	P30530
AMFPVVFHPVAPPKS	VPS13C	3216	Q709C8
HTPITVLMAAPVPLP	SETD2	216	Q9BYW2
EAPPSKMVLRIPHPI	YY1AP1	486	Q9H869
ADFLMKAPEPPPALI	YTHDC2	791	Q9H6S0
IPPPKLSVHDMKPLD	TRIP11	1876	Q15643
PETPSCPVKHTLMPE	PLIN5	446	Q00G26
PTESIIHVPPLDPSM	XIRP1	966	Q702N8
MPHTTPELQKGPSPI	TNRC6A	1491	Q8NDV7
MPPAGVIVSKPHPVT	KIAA0586	746	Q9BVV6
MHDAFEPVPILEKLP	VPS39	1	Q96JC1
LPSTPTMPLFPHVLD	ZC3H7B	221	Q9UGR2