Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	MRE11 SMARCA5 ATAD5 ZGRF1 UPF1 FANCM FBH1 SMARCA1 TOP2B	1.57e-06	127	172	9	GO:0008094
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	MRE11 SMARCA5 ATAD5 ZGRF1 UPF1 FANCM FBH1 N4BP2 SMARCA1 DNASE1L1 TOP2B	1.76e-05	262	172	11	GO:0140097
GeneOntologyMolecularFunction	ATP-dependent activity	MRE11 SMARCA5 TOR2A ATAD5 ZGRF1 MYO1H UPF1 FANCM ATP10A FBH1 SLFN13 DNAH17 SMARCA1 NAV3 DNAH6 DYNC1H1 TOP2B	2.38e-05	614	172	17	GO:0140657
GeneOntologyMolecularFunction	DNA helicase activity	MRE11 ZGRF1 UPF1 FANCM FBH1	1.95e-04	62	172	5	GO:0003678
GeneOntologyMolecularFunction	helicase activity	MRE11 SMARCA5 ZGRF1 UPF1 FANCM FBH1 SMARCA1	4.46e-04	158	172	7	GO:0004386
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH17 DNAH6 DYNC1H1	4.66e-04	18	172	3	GO:0008569
GeneOntologyMolecularFunction	small GTPase binding	RAP1GAP IPO7 DOCK9 DOCK10 ECT2 LLGL1 RASGRP3 GOLGA5 C9orf72 IPO11	4.84e-04	321	172	10	GO:0031267
Domain	DUF3699	GARIN2 TASOR2 GARIN1B	6.19e-05	9	172	3	IPR022168
Domain	DUF3699	GARIN2 TASOR2 GARIN1B	6.19e-05	9	172	3	PF12480
Domain	SLIDE	SMARCA5 SMARCA1	8.43e-05	2	172	2	IPR015195
Domain	ISWI_HAND-dom	SMARCA5 SMARCA1	8.43e-05	2	172	2	IPR015194
Domain	MAGEA3/MAGEA6	MAGEA3 MAGEA6	8.43e-05	2	172	2	IPR030097
Domain	SLIDE	SMARCA5 SMARCA1	8.43e-05	2	172	2	PF09111
Domain	HAND	SMARCA5 SMARCA1	8.43e-05	2	172	2	PF09110
Domain	ISWI	SMARCA5 SMARCA1	8.43e-05	2	172	2	IPR029915
Domain	ARM-like	KPNA4 MON2 IPO7 DOCK10 RICTOR ANKAR CEP70 ASPM STAG3 IPO11	2.07e-04	270	172	10	IPR011989
Domain	DBINO	SMARCA5 SMARCA1	2.51e-04	3	172	2	IPR020838
Domain	DBINO	SMARCA5 SMARCA1	2.51e-04	3	172	2	PF13892
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RAP1GAP ARHGEF28 HECW1 BACE1 RICTOR FANCM ATP10A TULP4 OSBPL3 N4BP2 RASGRP3 SOCS5 DNAH17 MINAR1 UNC80	4.71e-08	493	179	15	15368895
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	COL6A1 ZGRF1 BEND3 CRTC1 PALB2 HMG20B ZNF532 N4BP2 ZBTB21 TMF1 GOLGA5 PCM1 NPAT	2.98e-07	418	179	13	34709266
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	KPNA4 IPO7 ANK3 ITSN1 TASOR2 ZNF469 NUP155 TULP4 ZNF532 NFE2L2 TPX2 SCN10A DYNC1H1	4.11e-07	430	179	13	35044719
Pubmed	NLRC4 regulates caspase-1 and IL-1beta production in a CD11blowLy6Glow population of cells required for resistance to Pseudomonas aeruginosa keratitis.	ITGAM NLRC4 IL1B	5.34e-07	4	179	3	28961278
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MRE11 SMARCA5 IPO7 DOCK10 RICTOR UPF1 ECT2 ZBED5 LLGL1 NUP155 GRHPR ASPM SMARCA1 POLR1B EIF3I CORO7 GMPPB DYNC1H1 CNP TOP2B ALDH7A1 AHNAK2	2.01e-06	1353	179	22	29467282
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	MON2 SMARCA5 TOR2A RADX RICTOR ESYT2 NUP155 DHFR SMARCA1 POLR1B VPS51 GMPPB CNP IPO11	3.48e-06	606	179	14	36538041
Pubmed	CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis.	AMPH SMARCA5 ASPM SMARCA1	3.79e-06	21	179	4	22154806
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MON2 MRE11 SMARCA5 ATAD5 FAT3 KIAA1549 BEND3 RICTOR HMG20B ZNF469 EML5 OSBPL3 ZBTB21 ASPM SMARCA1 VPS51 UNC80 PCM1 WWC1	5.50e-06	1116	179	19	31753913
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FRAS1 IPO7 ANK3 ATAD5 ITSN1 KIAA1549 DNAJC18 RICTOR UPF1 ESYT2 LLGL1 NUP155 CDC123 N4BP2 RETREG1 ASPM GOLGA5 C9orf72 DCXR TOP2B PCM1 NPAT	8.99e-06	1487	179	22	33957083
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAP1GAP ARHGEF28 CRTC1 RICTOR DPP8 RFX7 ECT2 ESYT2 PHF3 OSBPL3 N4BP2 ZBTB21 EIF3I WNK3 PCM1 AHNAK2	1.08e-05	861	179	16	36931259
Pubmed	A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.	HECW1 CRTC1 ALDH1A2	1.10e-05	9	179	3	24121790
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	KPNA4 MON2 MRE11 ANK3 PITRM1 RADX CRTC1 DPP8 ECT2 EML5 OSBPL3 PLCL2 ZBTB21 MLF1 GOLGA5 VPS51 DYNC1H1 CNP RSPH10B IPO11	1.71e-05	1321	179	20	27173435
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	MON2 PITRM1 DOCK9 SHANK2 PLCL2 MINAR1	1.71e-05	104	179	6	10470851
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HECW1 DOCK9 DOCK10 ESYT2 PHF3 MINAR1 STK38L UNC80	2.34e-05	225	179	8	12168954
Pubmed	miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling.	MAGEA3 MAGEA6	2.63e-05	2	179	2	30056111
Pubmed	The first report of two homozygous sequence variants in FKRP and SELENON genes associated with syndromic congenital muscular dystrophy in Iran: Further expansion of the clinical phenotypes.	FKRP SELENON	2.63e-05	2	179	2	32864802
Pubmed	cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP.	CENPU MLF1	2.63e-05	2	179	2	15116101
Pubmed	NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense.	NLRC4 IL1B	2.63e-05	2	179	2	22484733
Pubmed	Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia.	NFE2L2 ASPM	2.63e-05	2	179	2	39097533
Pubmed	Tetrodotoxin-resistant voltage-gated sodium channel Nav 1.8 constitutively interacts with ankyrin G.	ANK3 SCN10A	2.63e-05	2	179	2	24903831
Pubmed	C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression.	UPF1 C9orf72	2.63e-05	2	179	2	32620797
Pubmed	Whole-genome sequencing in multiplex families with psychoses reveals mutations in the SHANK2 and SMARCA1 genes segregating with illness.	SHANK2 SMARCA1	2.63e-05	2	179	2	27001614
Pubmed	The protective effects of resveratrol on ulcerative colitis via changing the profile of Nrf2 and IL-1β protein.	NFE2L2 IL1B	2.63e-05	2	179	2	32888128
Pubmed	UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction.	UPF1 C9orf72	2.63e-05	2	179	2	33789100
Pubmed	Hox2 Genes Are Required for Tonotopic Map Precision and Sound Discrimination in the Mouse Auditory Brainstem.	HOXA2 HOXB2	2.63e-05	2	179	2	28052248
Pubmed	Genetic polymorphisms in the 5'-flanking region of human UDP-glucuronosyltransferase 2B7 affect the Nrf2-dependent transcriptional regulation.	NFE2L2 UGT2B7	2.63e-05	2	179	2	18622263
Pubmed	BACE1 interacts with nicastrin.	BACE1 NCSTN	2.63e-05	2	179	2	12054507
Pubmed	IPAF inflammasome is involved in interleukin-1β production from astrocytes, induced by palmitate; implications for Alzheimer's Disease.	NLRC4 IL1B	2.63e-05	2	179	2	24054992
Pubmed	Herpes simplex virus infection causes cellular beta-amyloid accumulation and secretase upregulation.	BACE1 NCSTN	2.63e-05	2	179	2	17980964
Pubmed	Sesamin inhibits IL-1β-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway.	NFE2L2 IL1B	2.63e-05	2	179	2	27863411
Pubmed	A Comprehensive Expression Analysis of Cancer Testis Antigens in Head and Neck Squamous Cell Carcinoma Revels MAGEA3/6 as a Marker for Recurrence.	MAGEA3 MAGEA6	2.63e-05	2	179	2	25564441
Pubmed	Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.	ITGAM CD4 CLCA1	2.85e-05	12	179	3	31201093
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	MON2 HEXA RADX ITSN1 PHF3 N4BP2 TPX2 MLF1 TMF1 SECISBP2 POLR1B GOLGA5 CORO7 PCM1	2.91e-05	733	179	14	34672954
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MRE11 SMARCA5 BEND3 POU2F2 ECT2 HMG20B ESYT2 DHFR TPX2 ZBTB21 SMARCA1 TMF1 PLA2G4A DYNC1H1 TOP2B	4.09e-05	857	179	15	25609649
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH17 DNAH6 DYNC1H1	4.68e-05	14	179	3	9373155
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 FRAS1 DOCK9 DOCK10 BEND3 LGI2 PHF3 PLCL2 NAV3 DYNC1H1	5.38e-05	407	179	10	12693553
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	MRE11 IPO7 TPX2 ASPM PLA2G4A DYNC1H1 PCM1 AHNAK2	5.84e-05	256	179	8	33397691
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ANK3 RADX ITSN1 KIAA1549 NUP155 SECISBP2 GOLGA5 AHNAK2	7.05e-05	263	179	8	34702444
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	ANK3 ITSN1 ADAM22 SHANK2 TULP4 DHFR MINAR1	7.68e-05	197	179	7	36604605
Pubmed	NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection.	NLRC4 IL1B	7.88e-05	3	179	2	22547706
Pubmed	The RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 Cells.	PLA2G4A IL1B	7.88e-05	3	179	2	21862584
Pubmed	TLR4 activation induces IL-1β release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung.	NLRC4 IL1B	7.88e-05	3	179	2	25085021
Pubmed	NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.	BACE1 NFE2L2	7.88e-05	3	179	2	31164420
Pubmed	cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loop.	PLA2G4A IL1B	7.88e-05	3	179	2	21771656
Pubmed	Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism.	SMARCA5 SMARCA1	7.88e-05	3	179	2	21738833
Pubmed	Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation.	NLRC4 NFE2L2	7.88e-05	3	179	2	24798340
Pubmed	H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts.	COL6A1 SOCS5	7.88e-05	3	179	2	33391546
Pubmed	C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa.	PDE6B ITGAM	7.88e-05	3	179	2	31209071
Pubmed	TIFA protein expression is associated with pulmonary arterial hypertension.	TIFA IL1B	7.88e-05	3	179	2	34238983
Pubmed	IL-4 induces reparative phenotype of RPE cells and protects against retinal neurodegeneration via Nrf2 activation.	PDE6B NFE2L2	7.88e-05	3	179	2	36539414
Pubmed	Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.	ITGAM IL1B	7.88e-05	3	179	2	20483667
Pubmed	Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation.	NLRC4 IL1B	7.88e-05	3	179	2	33178225
Pubmed	The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2.	NFE2L2 IPO11	7.88e-05	3	179	2	25378586
Pubmed	Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l.	SMARCA5 SMARCA1	7.88e-05	3	179	2	11359880
Pubmed	Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.	DOCK9 DOCK10	7.88e-05	3	179	2	32241915
Pubmed	mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation.	RICTOR SCN10A	7.88e-05	3	179	2	35579957
Pubmed	Expression of lineage markers by CD34+ hematopoietic stem cells of adult mice.	ITGAM CD4	7.88e-05	3	179	2	11937272
Pubmed	Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network.	POU2F2 CREB3L1	7.88e-05	3	179	2	28750683
Pubmed	Identification of Lmo1 as part of a Hox-dependent regulatory network for hindbrain patterning.	HOXA2 HOXB2	7.88e-05	3	179	2	17676642
Pubmed	Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.	RICTOR CNP	7.88e-05	3	179	2	24671993
Pubmed	Short-term interleukin-1(beta) increases the release of secreted APP(alpha) via MEK1/2-dependent and JNK-dependent alpha-secretase cleavage in neuroglioma U251 cells.	BACE1 IL1B	7.88e-05	3	179	2	15880353
Pubmed	NGF/TrkA promotes the vitality, migration and adhesion of bone marrow stromal cells in hypoxia by regulating the Nrf2 pathway.	NTRK1 NFE2L2	7.88e-05	3	179	2	35579787
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	SMARCA5 TASOR2 PHF3 TPX2 TOP2B	8.49e-05	86	179	5	37253089
Pubmed	Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	COL6A1 FKRP SELENON	8.64e-05	17	179	3	20301468
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	MAGEA3 MAGEA6 MRE11 FANCM ZBED5 CD4 NUP155 DYNC1H1 RSPH10B	1.14e-04	361	179	9	18976975
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	MON2 MRE11 RHBDF1 ZGRF1 DOCK9 ECT2 TULP4 RASGRP3 ASPM	1.19e-04	363	179	9	14691545
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	MRE11 SMARCA5 IPO7 PITRM1 DOCK10 POU2F2 ESYT2 SMARCA1 SARDH WNK3	1.25e-04	451	179	10	36168627
Pubmed	Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.	NLRC4 IL1B	1.57e-04	4	179	2	19222370
Pubmed	Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold.	MAPK12 CNP	1.57e-04	4	179	2	27070899
Pubmed	Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.	NFE2L2 IL1B	1.57e-04	4	179	2	30127006
Pubmed	Matrix metalloproteinase-9 participates in NGF-induced α-secretase cleavage of amyloid-β protein precursor in PC12 cells.	NTRK1 BACE1	1.57e-04	4	179	2	21321391
Pubmed	Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling.	NLRC4 IL1B	1.57e-04	4	179	2	26516283
Pubmed	Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis.	BACE1 ITGAM	1.57e-04	4	179	2	37819761
Pubmed	cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia.	NTRK1 MLF1	1.57e-04	4	179	2	10393836
Pubmed	BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase.	SMARCA5 BEND3	1.57e-04	4	179	2	26100909
Pubmed	Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1.	NLRC4 IL1B	1.57e-04	4	179	2	23024281
Pubmed	Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli.	NTRK1 SCN10A	1.57e-04	4	179	2	27604420
Pubmed	Degradation of AMPK by a cancer-specific ubiquitin ligase.	MAGEA3 MAGEA6	1.57e-04	4	179	2	25679763
Pubmed	Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes.	SPTA1 NFE2L2	1.57e-04	4	179	2	32663195
Pubmed	TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.	NLRC4 IL1B	1.57e-04	4	179	2	23225887
Pubmed	Identification and characterization of a novel mammalian isoform of the endocytic adaptor ITSN1.	AMPH ITSN1	1.57e-04	4	179	2	21712076
Pubmed	CD44-mediated phagocytosis induces inside-out activation of complement receptor-3 in murine macrophages.	RAP1GAP ITGAM	1.57e-04	4	179	2	17827392
Pubmed	KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.	NFE2L2 IPO11	1.57e-04	4	179	2	21383067
Pubmed	The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity.	NLRC4 IL1B	1.57e-04	4	179	2	18624356
Pubmed	A strategy focused on MAPT, APP, NCSTN and BACE1 to build blood classifiers for Alzheimer's disease.	BACE1 NCSTN	1.57e-04	4	179	2	25863267
Pubmed	Intersectin 1 forms complexes with SGIP1 and Reps1 in clathrin-coated pits.	AMPH ITSN1	1.57e-04	4	179	2	20946875
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	SMARCA5 ATAD5 RADX CENPU UPF1 ECT2 NUP155 PHF3 TPX2 ASPM POLR1B EIF3I TOP2B	1.67e-04	759	179	13	35915203
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KPNA4 SMARCA5 SPTA1 ITSN1 DNAJC18 BEND3 PALB2 TASOR2 SHANK2 N4BP2 DGKK ZBTB21 RETREG1 ASPM SMARCA1 ATG4C DNAH6 TOP2B CFAP46	1.74e-04	1442	179	19	35575683
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KIAA1549 BEND3 FANCM ZNF532 WNK3	1.81e-04	101	179	5	10997877
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MRE11 SMARCA5 ITSN1 RICTOR RFX7 PALB2 ESYT2 PHF3 TPX2 ZBTB21 PLA2G4A TOP2B PCM1	2.01e-04	774	179	13	15302935
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	KPNA4 SMARCA5 BEND3 LLGL1 NUP155 PHF3 TPX2 ZBTB21 EIF3I STK38L CNP	2.35e-04	583	179	11	29844126
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MON2 RADX ZGRF1 ITSN1 ALDH1A2 BRF1 N4BP2 ASPM SECISBP2 EIF3I PCM1	2.53e-04	588	179	11	38580884
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK3 CNP	2.61e-04	5	179	2	25362471
Pubmed	Microglial integrin, chemokine receptors, and inflammatory response vary with development.	ITGAM IL1B	2.61e-04	5	179	2	35609421
Pubmed	S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.	POU2F2 NPAT	2.61e-04	5	179	2	12887926
Pubmed	3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.	NFE2L2 IL1B	2.61e-04	5	179	2	24053646
Pubmed	mTORC1 promotes survival through translational control of Mcl-1.	CRTC1 RICTOR	2.61e-04	5	179	2	18664580
Pubmed	Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.	DOCK9 DOCK10	2.61e-04	5	179	2	15710388
Pubmed	Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.	NLRC4 IL1B	2.61e-04	5	179	2	27708283
Pubmed	PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.	BACE1 CRTC1	2.61e-04	5	179	2	24889041
GeneFamily	Armadillo repeat containing\|Importins	KPNA4 IPO7 IPO11	1.58e-04	18	108	3	596
GeneFamily	WD repeat domain containing	CFAP43 SEC31B LLGL1 EML5 TULP4 EIF3I CORO7	9.96e-04	262	108	7	362
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200	FAT3 CPED1 CREB3L1 ALDH1A2 CLCA1 SMARCA1 PLA2G4A WNK3	2.02e-05	138	176	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_100	FAT3 CPED1 CREB3L1 ALDH1A2 CLCA1 SMARCA1	2.13e-05	68	176	6	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_100
CoexpressionAtlas	dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_500	COL6A1 FAT3 CPED1 CREB3L1 CLCA1	2.17e-05	41	176	5	gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k2_500
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 HECW1 FAT3 SPTA1 ANO5 DGKK PCDH15 NAV3 MYOCD UNC80	4.06e-09	184	179	10	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 HECW1 FAT3 SPTA1 ANO5 DGKK PCDH15 NAV3 MYOCD UNC80	4.06e-09	184	179	10	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 HECW1 FAT3 SPTA1 ANO5 DGKK PCDH15 NAV3 MYOCD UNC80	4.06e-09	184	179	10	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 ZGRF1 CENPU ADAM22 ZNF354C ALDH1A2 TPX2 ASPM STAG3	3.61e-08	173	179	9	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 ZGRF1 CENPU ADAM22 ZNF354C ALDH1A2 TPX2 ASPM STAG3	3.61e-08	173	179	9	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TOR2A ATAD5 CENPU ECT2 TPX2 ASPM UGT2B7 GMPPB	6.71e-07	179	179	8	ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	ARHGEF28 GARNL3 FAT3 DOCK10 CPED1 ATP10A MYOCD STK38L	9.71e-07	188	179	8	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	PND10-Epithelial-Epithelial_Airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP43 CFAP54 ALDH1A2 MLF1 DNAH6 DCXR RSPH10B CFAP46	1.01e-06	189	179	8	407d8a59969d83f014600aae1a55092283a13970
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 ZGRF1 DOCK9 CENPU ECT2 ZNF732 TPX2 ASPM	1.05e-06	190	179	8	31de1727822e9818652946dfb962daee77ffad68
ToppCell	E18.5-Epithelial-Epithelial_Airway\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP43 CFAP54 ALDH1A2 MLF1 DNAH6 DCXR RSPH10B CFAP46	1.05e-06	190	179	8	5c012935ea5e35a2d0d08ea7dc04ffbe3c2a10ac
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ATAD5 ZGRF1 FAT3 CENPU ECT2 CPED1 ASPM MYOCD	1.05e-06	190	179	8	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	RAP1GAP ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.09e-06	191	179	8	e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ANK3 ANO5 CPED1 RASGRP3 PLCL2 RETREG1 MLF1 MYOCD	1.14e-06	192	179	8	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HECW1 ZGRF1 CENPU CPED1 ADARB2 ZNF732 DHFR MYOCD	1.18e-06	193	179	8	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ARHGEF28 ANK3 FAT3 SHANK2 OSBPL3 UGT2B7 WWC1	1.33e-06	196	179	8	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	ANK3 CFAP43 CFAP54 SHANK2 ASPM DNAH6 WWC1 CFAP46	1.33e-06	196	179	8	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 RAP1GAP ARHGEF28 ANK3 SHANK2 OSBPL3 UGT2B7 WWC1	1.33e-06	196	179	8	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	ANK3 CFAP43 CFAP54 SHANK2 ASPM DNAH6 WWC1 CFAP46	1.33e-06	196	179	8	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CENPU CP CCDC160 RSPH10B2 DHFR ASPM DNAH6 RSPH10B	1.38e-06	197	179	8	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	356C-Lymphocytic-ILC-ILC-2\|356C / Donor, Lineage, Cell class and subclass (all cells)	RADX DNAAF9 FANCM SEC31B LLGL1 DNAH17 POLR1B	3.18e-06	155	179	7	0fd66c623cb433ceaa893bc21ba2e3b394faaf70
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 HECW1 FAT3 ANKAR SCN10A PCDH15 UNC80	4.25e-06	162	179	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 ARHGEF28 CFAP54 ALDH1A2 SHANK2 UGT2B7 WWC1	5.40e-06	168	179	7	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 ZGRF1 CENPU ECT2 ZNF732 TPX2 ASPM	5.62e-06	169	179	7	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP ANK3 BEND3 RICTOR ATP10A ALDH1A2 CD4	6.07e-06	171	179	7	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP ANK3 BEND3 RICTOR ATP10A ALDH1A2 CD4	6.07e-06	171	179	7	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATAD5 CENPU ECT2 TASOR2 DHFR TPX2 MLF1	6.31e-06	172	179	7	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ARHGEF28 CFAP43 CFAP54 MLF1 DNAH6 RSPH10B CFAP46	6.80e-06	174	179	7	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 CENPU ECT2 ZNF732 SLFN13 TPX2 ASPM	6.80e-06	174	179	7	84da9faff088d05233183b425385beb054c92d1b
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ARHGEF28 CFAP43 CFAP54 MLF1 DNAH6 RSPH10B CFAP46	7.06e-06	175	179	7	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	droplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRE11 ATAD5 ZGRF1 CENPU SOCS5 DHFR TPX2	7.06e-06	175	179	7	6751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 TPK1 CFAP54 ALDH1A2 LGI2 DNAH17 UGT2B7	7.33e-06	176	179	7	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 TPK1 ALDH1A2 SHANK2 LGI2 DNAH17 UGT2B7	7.61e-06	177	179	7	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATAD5 ATP10A CD4 DHFR TPX2 ASPM MLF1	8.19e-06	179	179	7	54621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 CPED1 ADAM22 CREB3L1 ALDH1A2 PCDH15 NAV3	8.49e-06	180	179	7	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 ZGRF1 CENPU ECT2 ZNF732 TPX2 ASPM	8.49e-06	180	179	7	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	normal-na-Lymphocytic-lymphocyte-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ZGRF1 CENPU CRTC1 SEC31B PALB2 PLCL2 TPX2	9.80e-06	184	179	7	2c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 ANK3 CP SHANK2 EML5 PLA2G4A WWC1	9.80e-06	184	179	7	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 ANK3 CP SHANK2 PLA2G4A DCXR WWC1	1.01e-05	185	179	7	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 ZGRF1 CENPU ECT2 SLFN13 TPX2 ASPM	1.01e-05	185	179	7	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 ANK3 CP SHANK2 PLA2G4A DCXR WWC1	1.01e-05	185	179	7	929b68b05b7686341329ac756d7df172cb4b810b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 PPP1R3B CFAP43 ADARB2 CFAP54 RETREG1 WWC1	1.05e-05	186	179	7	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ARHGEF28 CP SHANK2 EML5 OSBPL3 WWC1	1.05e-05	186	179	7	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ADARB2 LGI2 OSBPL3 DNAH17 UGT2B7 WWC1	1.09e-05	187	179	7	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 ZGRF1 CENPU ECT2 SLFN13 TPX2 ASPM	1.09e-05	187	179	7	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 ZGRF1 CENPU ECT2 SLFN13 TPX2 ASPM	1.09e-05	187	179	7	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 CFAP43 ALDH1A2 LGI2 UGT2B7 DNAH6 WWC1	1.17e-05	189	179	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	ATAD5 CENPU ADAM22 RSPH10B2 DUSP29 TPX2 ASPM	1.17e-05	189	179	7	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CENPU KIAA1549 ECT2 DHFR TPX2 ZBTB21 CFAP46	1.21e-05	190	179	7	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 CFAP43 CFAP54 ALDH1A2 LGI2 UGT2B7 WWC1	1.25e-05	191	179	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATAD5 ZGRF1 SPTA1 CENPU ECT2 TPX2 ASPM	1.25e-05	191	179	7	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ZFP42 ARHGEF28 SHANK2 EML5 SLFN13 UGT2B7 WWC1	1.29e-05	192	179	7	d3634574b2e8d2ded6446969361b70761b331aea
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATAD5 CENPU ECT2 HOXA2 DHFR TPX2 ASPM	1.29e-05	192	179	7	f518839ecd9377537a414e8798766f7d91eafeac
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANK3 CFAP43 RSPH10B2 CFAP54 DNAH6 CFAP46 AHNAK2	1.34e-05	193	179	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 SMARCA5 DOCK10 ITGAM RASGRP3 NAV3 TMF1	1.34e-05	193	179	7	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ATAD5 ZGRF1 CENPU FANCM ECT2 TPX2 ASPM	1.34e-05	193	179	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 SMARCA5 DOCK10 ITGAM RASGRP3 NAV3 TMF1	1.34e-05	193	179	7	b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 SMARCA5 DOCK10 ITGAM RASGRP3 NAV3 TMF1	1.34e-05	193	179	7	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.38e-05	194	179	7	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCA5 N4BP2 ASPM TIFA CNP TOP2B PCM1	1.38e-05	194	179	7	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	FRAS1 ANK3 DUSP29 RASGRP3 RETREG1 MLF1 MYOCD	1.38e-05	194	179	7	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 RAP1GAP CENPU ECT2 TPX2 ASPM SERPIND1	1.38e-05	194	179	7	d790cfff3664e46fe2fd2f6b0c26896799927845
ToppCell	3'_v3-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	ATAD5 ZGRF1 CENPU SLFN13 DHFR TPX2 ASPM	1.38e-05	194	179	7	bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATAD5 CENPU ECT2 SLFN13 DHFR TPX2 ASPM	1.38e-05	194	179	7	4d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	ANK3 CFAP43 CFAP54 SHANK2 DNAH6 WWC1 CFAP46	1.43e-05	195	179	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	COVID-19-kidney-Proliferating_T_cell\|kidney / Disease (COVID-19 only), tissue and cell type	ZGRF1 SPTA1 DOCK10 CENPU ECT2 TPX2 ASPM	1.43e-05	195	179	7	7e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	ANK3 CFAP43 CFAP54 SHANK2 DNAH6 WWC1 CFAP46	1.43e-05	195	179	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.43e-05	195	179	7	1a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ANK3 CFAP43 CFAP54 SHANK2 DNAH6 WWC1 CFAP46	1.43e-05	195	179	7	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ARHGEF28 ANK3 DNAAF9 SHANK2 UGT2B7 WWC1	1.43e-05	195	179	7	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	ATAD5 ZGRF1 SPTA1 CENPU ECT2 TPX2 ASPM	1.43e-05	195	179	7	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 CENPU ECT2 SLFN13 DHFR TPX2 ASPM	1.48e-05	196	179	7	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ARHGEF28 CENPU SLFN13 DHFR TPX2 RETREG1 ASPM	1.48e-05	196	179	7	34bd155e6d848eb53d613997c0e244535de30ba3
ToppCell	myeloid-pro-pDC\|myeloid / Lineage and Cell class	ATAD5 CENPU OVOS2 DHFR TPX2 ASPM ALDH7A1	1.48e-05	196	179	7	70daf4fabb68aecc5cc9f03d6f6495dd29b74a16
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	ANK3 CFAP43 CFAP54 SHANK2 DNAH6 WWC1 CFAP46	1.48e-05	196	179	7	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	(3)_MNP-(3)_Macrophage_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	ARHGEF28 ATAD5 CENPU SLFN13 DHFR TPX2 ASPM	1.52e-05	197	179	7	048bc4f8fd5d4f394e2384700640f72042336597
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CENPU CFAP43 RSPH10B2 ASPM DNAH6 RSPH10B CFAP46	1.58e-05	198	179	7	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK-Cycling_NK\|lymph-node_spleen / Manually curated celltypes from each tissue	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.58e-05	198	179	7	b2868a897dd96494cf1829c30e0ce508f52efdf3
ToppCell	severe_COVID-19-T/NK_proliferative\|severe_COVID-19 / disease group, cell group and cell class (v2)	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.58e-05	198	179	7	ed86b0247006befe55400c287d334d2202b470bd
ToppCell	COVID-19_Moderate-T/NK_proliferative\|World / disease group, cell group and cell class	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.58e-05	198	179	7	bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.58e-05	198	179	7	bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell	COVID-19_Moderate-T/NK_proliferative\|COVID-19_Moderate / disease group, cell group and cell class	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.58e-05	198	179	7	166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.63e-05	199	179	7	11c3d9fe811a4619347f47d2b0e94066e3085625
ToppCell	Tracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRR4 RAP1GAP CP CREB3L1 SHANK2 UGT2B7 WWC1	1.63e-05	199	179	7	f37114cf849837fdb8ed9a767de773e8681b7df3
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.63e-05	199	179	7	36c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCell	(2)_B_cell-(24)_B_cell_cycling\|(2)_B_cell / shred on Cell_type and subtype	CENPU ECT2 SHANK2 ZNF732 DHFR TPX2 ASPM	1.63e-05	199	179	7	d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.63e-05	199	179	7	bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCell	10x5'-Lung-Myeloid_Mac-Cycling_Myeloid-Mac\|Lung / Manually curated celltypes from each tissue	ATAD5 CENPU SLFN13 DHFR TPX2 ASPM ALDH7A1	1.63e-05	199	179	7	dee1cf8ee850a2bd57349418a9bcc0948fe9ac9e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 CENPU ECT2 SLFN13 DHFR TPX2 ASPM	1.63e-05	199	179	7	4af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.63e-05	199	179	7	7beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCell	COVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative\|COVID-19_Mild / Disease group, lineage and cell class	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.63e-05	199	179	7	ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CENPU ECT2 HMG20B TPX2 CEP70 ASPM DCXR	1.63e-05	199	179	7	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast\|Megakaryocytic-erythropoietic / Lineage, cell class and subclass	ATAD5 CENPU ECT2 DHFR TPX2 ASPM APOL4	1.63e-05	199	179	7	fa698f00d2dad74d28b4696c8c23dce70f123e52
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ATAD5 ZGRF1 CENPU ECT2 TPX2 CEP70 ASPM	1.63e-05	199	179	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ATAD5 ZGRF1 CENPU ECT2 TPX2 CEP70 ASPM	1.68e-05	200	179	7	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	ATAD5 ZGRF1 CENPU ECT2 TPX2 CEP70 ASPM	1.68e-05	200	179	7	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	3'_v3-Lung-Lymphocytic_NK-Cycling_NK\|Lung / Manually curated celltypes from each tissue	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.68e-05	200	179	7	381bafdde6492f020ae93ab8fffa6215c631c570
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATAD5 ZGRF1 CENPU ECT2 SLFN13 TPX2 ASPM	1.68e-05	200	179	7	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATAD5 ZGRF1 CENPU ECT2 DHFR TPX2 ASPM	1.68e-05	200	179	7	43571c9284d4e41402a2d1eefc1efe2ce8476d4a
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATAD5 CENPU ECT2 SLFN13 DHFR TPX2 ASPM	1.68e-05	200	179	7	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	(24)_B_cell_cycling\|World / shred on Cell_type and subtype	CENPU ECT2 SHANK2 ZNF732 DHFR TPX2 ASPM	1.79e-05	202	179	7	a7c9b6b173701348ba35fbb975e0bdd3c1f1d5fe
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SMARCA5 ATAD5 TASOR2 PHF3 PCM1	1.10e-04	50	103	5	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drug	Clorgyline	MON2 MAGEA3 RICTOR NFE2L2 PHF3 CEP70 TMF1 ATG4C ZNF480 PCM1 NPAT	9.66e-08	168	179	11	ctd:D003010
Drug	AC1L4NWK	CP NCSTN DPP8 ALDH7A1	4.71e-06	15	179	4	CID000189017
Disease	Congenital muscular dystrophy	COL6A1 FKRP SELENON GMPPB	5.20e-07	12	171	4	cv:C0699743
Disease	Hereditary Sensory Autonomic Neuropathy, Type 5	NTRK1 RETREG1 SCN10A	6.58e-06	7	171	3	C0020075
Disease	Schizophrenia	ANK3 NTRK1 BACE1 CP ITGAM ITIH1 ALDH1A2 EML5 PLCL2 APOL4 PLA2G4A ZNF480 C9orf72 IL1B WNK3 CNP PCM1	1.62e-05	883	171	17	C0036341
Disease	thiamine measurement	CRTC1 ANO5 N4BP2	2.23e-05	10	171	3	EFO_0010540
Disease	schizophrenia (is_implicated_in)	ANK3 NTRK1 NCSTN APOL4 CNP	9.25e-05	78	171	5	DOID:5419 (is_implicated_in)
Disease	central nervous system disease (implicated_via_orthology)	SMARCA5 SEC31B SMARCA1	1.01e-04	16	171	3	DOID:331 (implicated_via_orthology)
Disease	HSAN Type IV	NTRK1 RETREG1	1.99e-04	4	171	2	C0020074
Disease	Hereditary Sensory Radicular Neuropathy	NTRK1 RETREG1	1.99e-04	4	171	2	C0086405
Disease	Hereditary Sensory and Autonomic Neuropathies	NTRK1 RETREG1	1.99e-04	4	171	2	C0027889
Disease	C-reactive protein measurement	TDRD15 RAP1GAP ARHGEF28 ANK3 PPP1R3B SETD4 RICTOR CREB3L1 ZNF469 ALDH1A2 LLGL1 NFE2L2 SPATA16 DNAH17 PCDH15 POLR1B IL1B TOP2B	2.36e-04	1206	171	18	EFO_0004458
Disease	late-onset Alzheimers disease	RHBDF1 ANK3 FAT3 ZNRF4 METTL21EP MEI4 SHANK2 DNAH6	3.19e-04	292	171	8	EFO_1001870
Disease	Hereditary Sensory Autonomic Neuropathy, Type 2	NTRK1 RETREG1	3.30e-04	5	171	2	C0020072
Disease	interleukin-10 receptor subunit beta measurement	IL10RB ITSN1	3.30e-04	5	171	2	EFO_0020489
Disease	age at menopause	ZFP42 GCM2 IPO7 DOCK10 FANCM TASOR2 ESYT2 DYNC1H1	3.99e-04	302	171	8	EFO_0004704
Disease	Pancytopenia	FANCM PALB2 DHFR	4.51e-04	26	171	3	C0030312
Disease	Sensory Neuropathy, Hereditary	NTRK1 RETREG1	4.93e-04	6	171	2	C0699739
Disease	congenital muscular dystrophy (implicated_via_orthology)	COL6A1 DYNC1H1	4.93e-04	6	171	2	DOID:0050557 (implicated_via_orthology)
Disease	Qualitative or quantitative defects of alpha-dystroglycan	FKRP GMPPB	4.93e-04	6	171	2	cv:C2936406
Disease	Schizoaffective Disorder	NTRK1 PLA2G4A C9orf72	6.25e-04	29	171	3	C0036337
Disease	Congenital Pain Insensitivity	NTRK1 SCN10A	6.88e-04	7	171	2	C0002768
Disease	Manic Disorder	ANK3 NTRK1 ITIH1 SHANK2	7.82e-04	71	171	4	C0024713
Disease	mean reticulocyte volume	RAP1GAP RNPEPL1 SPTA1 ITSN1 BEND3 DPP8 CPED1 ZNF469 BRF1 PLCL2 TPX2 PCM1 IPO11	8.16e-04	799	171	13	EFO_0010701
Disease	bitter non-alcoholic beverage consumption measurement	AMPH ITSN1 N4BP2	8.38e-04	32	171	3	EFO_0010093
Disease	Muscular Dystrophy	COL6A1 SELENON	9.14e-04	8	171	2	C0026850
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	TDRD15 ALDH1A2	9.14e-04	8	171	2	EFO_0008589, EFO_0008595
Disease	Hereditary Sensory Autonomic Neuropathy, Type 1	NTRK1 RETREG1	9.14e-04	8	171	2	C0020071
Disease	Alzheimer's disease (is_implicated_in)	NTRK1 BACE1 NCSTN NFE2L2 IL1B	1.05e-03	132	171	5	DOID:10652 (is_implicated_in)
Disease	interleukin 2 receptor antagonist measurement	ZNRF4 ZNF469 LGI2	1.09e-03	35	171	3	EFO_0008332
Disease	Manic	ANK3 NTRK1 ITIH1 SHANK2	1.11e-03	78	171	4	C0338831
Disease	Depression, Bipolar	ANK3 NTRK1 ITIH1 SHANK2	1.17e-03	79	171	4	C0005587
Disease	anemia (phenotype), response to ribavirin	RASGRP3 DNAH17	1.17e-03	9	171	2	EFO_0004272, GO_1901559
Disease	interferon alpha/beta receptor 1 measurement	IL10RB ITSN1	1.17e-03	9	171	2	EFO_0021850
Disease	phosphatidylcholine measurement	TDRD15 ZGRF1 MYO1H MEI4 ALDH1A2 SOCS5 DYNC1H1	1.39e-03	284	171	7	EFO_0010226
Disease	neuroimaging measurement, brain volume measurement	FAT3 BEND3 POU2F2 CPED1 ALDH1A2 RASGRP3 NAV3	1.45e-03	286	171	7	EFO_0004346, EFO_0006930
Disease	Papillary thyroid carcinoma	NTRK1 GOLGA5 DYNC1H1 PCM1	1.60e-03	86	171	4	C0238463
Disease	Bipolar Disorder	ANK3 NTRK1 DOCK9 ITGAM PALB2 ITIH1 SHANK2 PLA2G4A IL1B	1.94e-03	477	171	9	C0005586
Disease	pulmonary fibrosis (implicated_via_orthology)	NFE2L2 IL1B	2.12e-03	12	171	2	DOID:3770 (implicated_via_orthology)
Disease	phosphoglycerides measurement	TDRD15 MYO1H ALDH1A2	2.73e-03	48	171	3	EFO_0022291
Disease	Psychotic Disorders	ANK3 NTRK1 C9orf72 WWC1	2.87e-03	101	171	4	C0033975
Disease	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K	FKRP GMPPB	2.90e-03	14	171	2	C1836373
Disease	alpha-Dystroglycanopathies	FKRP GMPPB	2.90e-03	14	171	2	C2936406
Disease	Fukuyama Type Congenital Muscular Dystrophy	FKRP GMPPB	2.90e-03	14	171	2	C0410174
Disease	level of Phosphatidylcholine (18:1_18:2) in blood serum	ALDH1A2 ATG4C	2.90e-03	14	171	2	OBA_2045100
Disease	Muscle eye brain disease	FKRP GMPPB	2.90e-03	14	171	2	C0457133
Disease	Autosomal recessive limb-girdle muscular dystrophy	FKRP ANO5	2.90e-03	14	171	2	cv:C2931907
Disease	Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1	FKRP GMPPB	2.90e-03	14	171	2	C4284790
Disease	Hereditary Breast and Ovarian Cancer Syndrome	MRE11 PALB2	2.90e-03	14	171	2	C0677776
Disease	lipoprotein measurement	TDRD15 MYO1H ALDH1A2 LLGL1	3.30e-03	105	171	4	EFO_0004732
Disease	Walker-Warburg congenital muscular dystrophy	FKRP GMPPB	3.34e-03	15	171	2	C0265221
Disease	low density lipoprotein triglyceride measurement	TDRD15 ALDH1A2	3.34e-03	15	171	2	EFO_0009946
Disease	1,3,7-trimethylurate measurement	FRAS1 ALDH1A2	3.34e-03	15	171	2	EFO_0021172
Disease	immature platelet count	RNPEPL1 DOCK10 ESYT2 BRF1	3.42e-03	106	171	4	EFO_0803544
Disease	Neuralgia, Supraorbital	NTRK1 SCN10A	3.80e-03	16	171	2	C0038870
Disease	Neuralgia	NTRK1 SCN10A	3.80e-03	16	171	2	C0027796
Disease	Neuralgia, Atypical	NTRK1 SCN10A	3.80e-03	16	171	2	C0234247
Disease	Neuralgia, Stump	NTRK1 SCN10A	3.80e-03	16	171	2	C0234249
Disease	Neuralgia, Iliohypogastric Nerve	NTRK1 SCN10A	3.80e-03	16	171	2	C0423712
Disease	Neuralgia, Perineal	NTRK1 SCN10A	3.80e-03	16	171	2	C0423711
Disease	4-acetamidobutanoate measurement	ALDH1A2 MAPK12	3.80e-03	16	171	2	EFO_0021003
Disease	Paroxysmal Nerve Pain	NTRK1 SCN10A	3.80e-03	16	171	2	C0751373
Disease	Nerve Pain	NTRK1 SCN10A	3.80e-03	16	171	2	C0751372
Disease	Neuralgia, Ilioinguinal	NTRK1 SCN10A	3.80e-03	16	171	2	C0751371
Disease	Neuralgia, Vidian	NTRK1 SCN10A	3.80e-03	16	171	2	C0042656
Disease	HOMA-B	ATP10A PCDH15 NAV3	4.02e-03	55	171	3	EFO_0004469
Disease	Inborn Errors of Metabolism	DHFR PLA2G4A	4.29e-03	17	171	2	C0025521
Disease	diabetic neuropathy (biomarker_via_orthology)	NTRK1 IL1B	4.29e-03	17	171	2	DOID:9743 (biomarker_via_orthology)
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	TDRD15 ALDH1A2	4.29e-03	17	171	2	EFO_0022232
Disease	immature platelet fraction	RNPEPL1 DOCK10 ESYT2 BRF1	4.43e-03	114	171	4	EFO_0009187
Disease	Alzheimer's disease (implicated_via_orthology)	PITRM1 NCSTN IL1B	4.45e-03	57	171	3	DOID:10652 (implicated_via_orthology)
Disease	IGA glomerulonephritis	DOCK10 ITGAM PADI3	4.67e-03	58	171	3	EFO_0004194
Disease	Amyotrophic Lateral Sclerosis	ARHGEF28 PLA2G4A C9orf72	4.67e-03	58	171	3	C0002736
Disease	Alzheimer's disease (biomarker_via_orthology)	BACE1 NFE2L2 IL1B	4.67e-03	58	171	3	DOID:10652 (biomarker_via_orthology)
Disease	Bone marrow hypocellularity	FANCM PALB2	4.81e-03	18	171	2	C1855710
Disease	esophageal adenocarcinoma, digestive system disease, Barrett's esophagus	CRTC1 ALDH1A2	4.81e-03	18	171	2	EFO_0000280, EFO_0000405, EFO_0000478
Disease	esophageal adenocarcinoma	HECW1 CRTC1	4.81e-03	18	171	2	EFO_0000478
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	TDRD15 ALDH1A2	4.81e-03	18	171	2	EFO_0008317, EFO_0008589
Disease	coronary artery calcification	ANK3 DOCK10 ALDH1A2 CLCA1 OSBPL3 NAV3 DNAH6 ALDH7A1	4.89e-03	450	171	8	EFO_0004723

Protein segments in the cluster

Peptide	Gene	Start	Entry
PVTFRDVAVFFSQDE	ZNF354C	11	Q86Y25
SDLFDTDLDFPDQSI	ATAD5	1576	Q96QE3
VFDQSFDFSVSLPEV	ESYT2	851	A0FGR8
DDSLEPFFDSLVKQT	BACE1	191	P56817
LEDGSFFNETDVVFP	CFAP43	201	Q8NDM7
LPSDAEEFSTFINSI	CFAP54	1561	Q96N23
SNDLFSSFFDDPVLD	CREB3L1	51	Q96BA8
PLTFDFQLEFEEALA	C1orf141	41	Q5JVX7
QELFLIEDQATFFPS	ANO5	196	Q75V66
FPNESSLSIFSEIFQ	CPED1	411	A4D0V7
FEDADLSLVVPSALF	ALDH7A1	306	P49419
GFFIEPTVFSNVTDD	ALDH1A2	396	O94788
TPNVLSFALDFDEAT	APOL4	226	Q9BPW4
PFQFEITFECIEDLS	ASF1A	21	Q9Y294
RLFEFSLDDLPSEFQ	ADAM22	191	Q9P0K1
IDVFDFPDNSDVSSI	CENPU	41	Q71F23
SEFDPSESFSPDLFV	CFAP46	36	Q8IYW2
ASFSPDILADIFELF	CMTR2	16	Q8IYT2
TPFDEFDFAVTNLAV	ASPM	956	Q8IZT6
SFVDVSIKDFPLETF	ATG4C	351	Q96DT6
LSPELSDVFDFFIAL	ATP10A	561	O60312
ISFFEDNFVPEISVT	AMPH	321	P49418
DFTSDQADFPDTLFQ	ADARB2	211	Q9NS39
SPEFENVFVVTDFQD	ECT2	121	Q9H8V3
FSFPIFLLEDENETK	NCSTN	176	Q92542
AEAQIADFSDPAFIS	SERPIND1	246	P05546
FSEFEEDPQVFNTLF	KIAA1549	471	Q9HCM3
QSFSPLVETFTLFDS	KIAA1549	661	Q9HCM3
IDFFTVHSTRPEDEF	LLGL1	341	Q15334
LEQTESDPAFQALFD	NPAT	316	Q14207
FIVELFSTSQPEIFE	RADX	416	Q6NSI4
LVQLFPELFSDVDFS	BEND3	271	Q5T5X7
ELDSFETNTEPDFNI	ARHGEF28	516	Q8N1W1
FDISTPSIENALEDF	ANKAR	386	Q7Z5J8
FPTVFDENESLLLED	CP	581	P00450
AQFSIDTSDIFDPEF	OVOS1	356	Q6IE37
DSNFEPELVFLEFFE	RSPH10B	616	P0C881
DSNFEPELVFLEFFE	RSPH10B2	616	B2RC85
DLSEVTFSLQVSPDF	DDI1	11	Q8WTU0
NFSSTFFLEDDPEDI	DGKK	796	Q5KSL6
QENDLSTFFPFIFEE	IL1B	86	P01584
VLNETSFIFTEFLEP	NTRK1	321	P04629
SFIFTEFLEPAANET	NTRK1	326	P04629
FTVSDGTNPFFIIEE	FRAS1	2401	Q86XX4
STFPDLESEFQAALS	MAGEA3	96	P43357
STFPDLESEFQAALS	MAGEA6	96	P43360
QLVFFDFSTKEFLPD	NLRC4	966	Q9NPP4
LPLEFDFLFSQSQAE	ENTPD7	196	Q9NQZ7
AFDLEIPKTAFISDF	ITIH1	86	P19827
FLNSLEFEDPELSAT	WWC1	561	Q8IX03
SEPDDELLFDFLNSS	GOLGA5	116	Q8TBA6
AEQFSFVSLPTDVLE	HECW1	266	Q76N89
LTVDDFEFRTDQFLP	IPO11	541	Q9UI26
DEKSVSSNLFLPFEE	FANCM	951	Q8IYD8
LLSETADPFFVLNSD	GMPPB	96	Q9Y5P6
TDLDFSPFDDFLLAT	CORO7	81	P57737
LDDQDFTSFDLFPEG	FAM199X	101	Q6PEV8
LSVSSNFEPFATDDL	PCM1	1496	Q15154
DVFEDFISPTTAAQT	IPO7	381	O95373
LNGPFFTSEDEDVFL	PDE6B	196	P35913
EENSLDSFVFDTLIP	NAV3	2021	Q8IVL0
TFPFVDDNEVSSATF	NFE2L2	126	Q16236
PFLEVTKEAFDRSFE	DCXR	91	Q7Z4W1
EPSDLEELEQFARTF	POU2F2	196	P09086
FTQLEFGDEPFNTVE	LCN6	121	P62502
DEVEDSSEFVSFFPD	GBP7	161	Q8N8V2
FKELFDLEEISSFPS	METTL21EP	241	A6NDL7
PELANTFEDFLFTKS	MON2	1491	Q7Z3U7
FSIDTSDIFDPEFNL	OVOS2	386	Q6IE36
LLDDSNEDFSASPIF	PADI3	271	Q9ULW8
NEDFSASPIFTDTVV	PADI3	276	Q9ULW8
PEFNLFLDSVVFESN	GARIN1B	66	Q96KD3
STSTFFLDINEDTEP	RICTOR	1056	Q6R327
SPSIFNIDFLDVTDL	MYOCD	911	Q8IZQ8
FTFSEDDPILQIAID	NUP155	271	O75694
DSPVPFSEEELDFFT	HOXB2	331	P14652
FLSITDFQLPDEDFG	PALB2	606	Q86YC2
PDQEASITFLVEAFD	PCDH15	886	Q96QU1
SEFEFTDFTLPSQTQ	UPF1	31	Q92900
DSFDTFIRTQFDDNP	DNAH6	2011	Q9C0G6
PSLASFDAIFVDEAQ	FBH1	636	Q8NFZ0
FDFPTSFQLTEEEAL	DNASE1L1	246	P49184
DLLFFPSDDFSAATV	DOCK10	71	Q96BY6
TTNVEPFFVTLSLFD	DOCK9	391	Q9BZ29
DFNPFGEVTDSLLFT	CDC123	246	O75794
LEEHEEFFPAFQAFT	CEP70	556	Q8NHQ1
FQDCPVDLFFVLDTS	COL6A1	31	P12109
VEADDLPTFDLSVFF	DUSP29	111	Q68J44
IPDSAESLFSENETF	DNAH17	696	Q9UFH2
DVSFDSDSQFPLDEL	CRTC1	586	Q6UUV9
FVSFFDLRDPSQIDN	EIF3I	121	Q13347
FPQSHEEEIEFIFAS	DPP8	456	Q6V1X1
QDFESDTFFPEIDLE	DHFR	141	P00374
ITVFERDQFSPDDFL	ITSN1	1661	Q15811
EAAEFQAEFVSTPEL	GRHPR	191	Q9UBQ7
PFSFSILSGNEEEEF	FAT3	3481	Q8TDW7
FFSAQDVLEETSEPE	CCDC160	16	A6NGH7
GEQVEFSFPLAFTVE	CD4	216	P01730
SFFANFDTEIPFLLE	DNAAF9	241	Q5TEA3
LSQFFPEAISFIDEA	DUSP7	306	Q16829
SFFGTDTILESPDDF	ANK3	2101	Q12955
ELQFPFLQDEDTVAT	CNP	31	P09543
NTLLFFSFPLSDEND	IL10RB	276	Q08334
DLEPFSDPFTFELDN	CDH26	526	Q8IXH8
FEADITPEELFNVFF	DNAJC18	166	Q9H819
DQDIDLSPSFVIFLS	DYNC1H1	3666	Q14204
DFTLTISSLQPEDFA	IGKV3-7	91	A0A075B6H7
IFVAEFRPDSDTQFV	EML5	1516	Q05BV3
FEAFDNAVPELVDSF	FKRP	56	Q9H9S5
EFPPDFAEAFESQLS	SLFN13	356	Q68D06
TDESFTPDLNIFQDV	C9orf72	356	Q96LT7
SSPFQLTAFSDEDII	GARNL3	996	Q5VVW2
FFDAQEVLLSPSSSE	OSBPL3	451	Q9H4L5
ESESFVLDFSQPSAD	PPP1R3B	106	Q86XI6
ADFDIFDDPESPFST	PLA2G4A	666	P47712
PVDISADSLDFFTDT	HOXA2	351	O43364
LNTEEVPDFERSFFN	MINAR1	371	Q9UPX6
EGTFFINKTEIEDFP	HEXA	151	P06865
STFDVPIFTEEFLDQ	HMG20B	181	Q9P0W2
SIDFPEFTDITDITD	GARIN2	231	Q8N9W8
DETIFQLSDAFPLFT	MEI4	351	A8MW99
SFLSFFPELKEQSVD	RNPEPL1	486	Q9HAU8
DDTSNFDDFPESDIL	STK38L	406	Q9Y2H1
FLLPDVFNSADDFDS	SMARCA1	356	P28370
SFDQDSDVDIFPSDF	TOP2B	1576	Q02880
FFDTFDPSLVSTEDE	SOCS5	246	O75159
GESLEFFETQFILSP	TIFA	131	Q96CG3
AVSDPSDFSIQLEDF	TDRD15	1741	B5MCY1
PNDIELFQIDDETFF	LGI2	326	Q8N0V4
EVFSRDLSDFPSLEN	RETREG1	341	Q9H6L5
SQEDFESIAANFPFL	RASGRP3	441	Q8IV61
LENPEDFDIVTETSF	GCM2	211	O75603
FDESFEFQINLPELA	PLCL2	811	Q9UPR0
VKIFFSDLSQDPTED	PIK3R6	541	Q5UE93
SFLLPDITDTFEAFT	PITRM1	331	Q5JRX3
FTPASFLEEDTTDFP	RHBDF1	241	Q96CC6
TTDFPDELDTSFFAR	RHBDF1	251	Q96CC6
SEEELFSTNEESPAF	RAP1GAP	206	P47736
FSTNEESPAFVEFLE	RAP1GAP	211	P47736
FFSSLQPLFAEAVDS	SETD4	176	Q9NVD3
TSKPEFEFTTLDFPE	SECISBP2	211	Q96T21
FEFTTLDFPELQGAE	SECISBP2	216	Q96T21
FDAPAEDIASVASFI	SPATA16	216	Q9BXB7
ALVSELLDFFFISEP	SCGB1D2	26	O95969
EASASSAFFDELVPQ	SEC31B	536	Q9NQW1
FPENSEVTFNITFDV	ITGAM	871	P11215
TNFIPEQFLDDFIDL	MRE11	226	P49959
EVLDADLSNEAFPFS	SARDH	696	Q9UL12
LASVDLDEDFIFTEP	SHANK2	1396	Q9UPX8
ITFFDARESFSPEEK	AHNAK2	5731	Q8IVF2
SEEVFLFKPENITFE	CLCA1	821	A8K7I4
VLDSTTFFPEDEQLF	TOR2A	291	Q5JU69
LFSERIDVFSPVEFN	VPS51	681	Q9UID3
EFQDSSESEPELFIS	TULP4	1401	Q9NRJ4
FSQFSPISSAEEFDD	ZNF532	126	Q9HCE3
DESENFFSAFLSPTD	TMF1	91	P82094
SQTVFQLDFCEPDAF	ZBTB21	66	Q9ULJ3
SAIDAEFSLFSDPQA	UNC80	2136	Q8N2C7
VFFPEATLQSELASF	STAG3	826	Q9UJ98
FDPEATQFITFSALS	SCN10A	1751	Q9Y5Y9
PEEIESNLFSFSSTF	SELENON	551	Q9NZV5
DNSSSVDFADLPALF	ZNRF4	106	Q8WWF5
NSSFEDDPFFSESIL	MLF1	6	P58340
APEEENDFFNSFTTV	PHF3	1391	Q92576
ESYFPFDDELTQDSI	RFX7	776	Q2KHR2
EAPTFQALEDFSAEL	SPTA1	1341	P02549
EFEDTPTSQLTIDEF	BRF1	266	Q92994
EDFTFTIPDVEDSSQ	PRR4	26	Q16378
FSQPILEEDSLFESL	ZFP42	81	Q96MM3
DNPEIDSSFIDVFAD	ZNF469	856	Q96JG9
PPSLFDDEVSFSQLF	ZNF469	2821	Q96JG9
TPIFNRNDFDDSSFL	ZNF480	176	Q8WV37
EENFDCFPTLSDFLT	ZBED5	521	Q49AG3
FSIEPEDQNETFFSE	ZGRF1	1111	Q86YA3
AEEINVTSDFPFDSV	TASOR2	1381	Q5VWN6
PQFSIDDAFELSLED	TMEM134	6	Q9H6X4
FTQDFLPVQGIEDSF	ZNF732	81	B4DXR9
QESRFDVIFADAIFP	UGT2B7	141	P16662
LNFLLPDVFNSADDF	SMARCA5	351	O60264
DATPFIFSEENSALE	POLR1B	946	Q9H9Y6
ESFLPEFINGDFDSI	TPK1	61	Q9H3S4
EFKEFQDFSSLPDTR	nan	36	A6NHS1
DAPSDFINFSSLDDE	TPX2	11	Q9ULW0
EAIEFSFNLETDTPE	WNK3	446	Q9BYP7
IDQFFSSDDIDEDPS	KPNA4	481	O00629
DVFTPDETLDDFTDF	MAPK12	91	P53778
FSVIDFTEADLENLF	MYO1H	256	Q8N1T3
ETEETPSELSFQDFE	N4BP2	1601	Q86UW6