Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessT cell activation

MYH9 RIPOR2 LRRC32 SLFN12 TSC2 SOCS6 ITGAX STAT6 LGALS8 ARMC5 ADAM17 PRKDC TREML2

1.73e-057019413GO:0042110
GeneOntologyBiologicalProcesslymphocyte activation

MYH9 RIPOR2 NTRK1 LRRC32 SLFN12 TSC2 SOCS6 ITGAX STAT6 LGALS8 ARMC5 TLR4 ADAM17 PRKDC TREML2

3.35e-059769415GO:0046649
GeneOntologyBiologicalProcessregulation of dendritic spine development

TANC2 KIF1A TSC2 SHANK3 NEURL1

6.03e-0591945GO:0060998
GeneOntologyBiologicalProcesspositive regulation of endothelial tube morphogenesis

LCN2 ITGAX

6.15e-053942GO:1905956
MousePhenoabnormal iridocorneal angle

PRSS56 LGR4 KERA ADAM17

4.74e-0621774MP:0004221
MousePhenoabnormal aqueous drainage system morphology

PRSS56 LGR4 KERA ADAM17

5.77e-0622774MP:0005198
DomainLRR_8

NTRK1 LRRC32 LGR4 KERA LRRC43 BGN LRRC3 PRELP TLR4

2.40e-07171969PF13855
DomainLRRNT

LRRC32 LGR4 KERA BGN LRRC3 PRELP

2.97e-0753966PF01462
DomainLRR

LRRC32 LGR4 KERA LRRC43 BGN LRRC3 PRELP TLR4

9.23e-06201968PS51450
DomainLeu-rich_rpt

NTRK1 LRRC32 LGR4 KERA LRRC43 BGN LRRC3 PRELP TLR4

1.08e-05271969IPR001611
DomainLRRNT

LRRC32 LGR4 KERA BGN LRRC3 PRELP

1.13e-0598966IPR000372
DomainLRRNT

LRRC32 LGR4 KERA BGN LRRC3 PRELP

1.13e-0598966SM00013
DomainLRR_TYP

LRRC32 LGR4 KERA BGN LRRC3 PRELP TLR4

3.57e-05177967SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC32 LGR4 KERA BGN LRRC3 PRELP TLR4

3.57e-05177967IPR003591
Domain-

NTRK1 LRRC32 LGR4 KERA LRRC43 BGN LRRC3 PRELP TLR4

4.09e-053219693.80.10.10
DomainL_dom-like

NTRK1 LRRC32 LGR4 KERA LRRC43 BGN LRRC3 PRELP TLR4

4.83e-05328969IPR032675
DomainZF_ZZ_2

DRP2 ZSWIM2 UTRN

1.02e-0418963PS50135
DomainZF_ZZ_1

DRP2 ZSWIM2 UTRN

1.02e-0418963PS01357
DomainZZ

DRP2 ZSWIM2 UTRN

1.02e-0418963PF00569
DomainZnf_ZZ

DRP2 ZSWIM2 UTRN

1.20e-0419963IPR000433
DomainZnF_ZZ

DRP2 ZSWIM2 UTRN

1.20e-0419963SM00291
DomainLRR_1

LRRC32 LGR4 KERA BGN LRRC3 PRELP TLR4

1.36e-04219967PF00560
Domain-

RIPOR2 PSMD5 TSC2 ODAD2 ARMC5 UTP20 PRKDC

1.48e-042229671.25.10.10
DomainTPR-like_helical_dom

TANC2 RGPD2 RANBP2 COPB2 CFAP54 TTC31 PRKDC

2.00e-04233967IPR011990
DomainARM-type_fold

DOCK1 RIPOR2 PSMD5 TSC2 ODAD2 ARMC5 UTP20 PRKDC

3.59e-04339968IPR016024
DomainEF-hand_dom_typ1

DRP2 UTRN

3.87e-046962IPR015153
DomainEF-hand_dom_typ2

DRP2 UTRN

3.87e-046962IPR015154
DomainEF-hand_2

DRP2 UTRN

3.87e-046962PF09068
DomainEF-hand_3

DRP2 UTRN

3.87e-046962PF09069
DomainARM-like

RIPOR2 PSMD5 TSC2 ODAD2 ARMC5 UTP20 PRKDC

4.87e-04270967IPR011989
DomainTPR-contain_dom

TANC2 RGPD2 RANBP2 TTC31 PRKDC

1.06e-03150965IPR013026
DomainTPR_REGION

TANC2 RGPD2 RANBP2 TTC31 PRKDC

1.62e-03165965PS50293
DomainTPR

TANC2 RGPD2 RANBP2 TTC31 PRKDC

1.62e-03165965PS50005
DomainRan_BP1

RGPD2 RANBP2

1.67e-0312962PF00638
DomainRANBD1

RGPD2 RANBP2

1.67e-0312962PS50196
DomainClass_I_gatase-like

TCAF2 CTPS2

1.67e-0312962IPR029062
DomainRanBD

RGPD2 RANBP2

1.97e-0313962SM00160
DomainRan_bind_dom

RGPD2 RANBP2

1.97e-0313962IPR000156
DomainHEAT

ODAD2 UTP20 PRKDC

3.31e-0358963IPR000357
DomainCyclophilin-type_PPIase_CS

RANBP2 PPIH

4.22e-0319962IPR020892
Domain-

TANC2 RGPD2 RANBP2 CFAP54 TTC31

4.31e-032079651.25.40.10
DomainTPR

TANC2 RGPD2 RANBP2 TTC31

4.42e-03129964SM00028
DomainTPR_repeat

TANC2 RGPD2 RANBP2 TTC31

4.93e-03133964IPR019734
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TCAF2 MYH9 ITGAX ANKRD27 ARMC5 SIGLEC1

1.47e-078597615449545
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 MYH9 KIF1A PCDHGB3 COPB2 TSC2 ARHGEF17 TMEM260 UTP20 CHD6 PRKDC UTRN

1.02e-06736971229676528
Pubmed

A cell-intrinsic role for TLR2-MYD88 in intestinal and breast epithelia and oncogenesis.

TLR4 PRKDC IL1R1

1.75e-06997325362351
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 EARS2 BICRA PRSS56 FBRS LGR4 ZFHX4 TRIM56 NEURL1 MTR ADAM17 SIGLEC1 PPIH SORL1

2.66e-061116971431753913
Pubmed

Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy.

KERA BGN PRELP

3.41e-061197312796502
Pubmed

Skeletal muscle TLR4 and TACE are associated with body fat percentage in older adults.

TLR4 ADAM17

7.70e-06297226988770
Pubmed

Crystallization and preliminary crystallographic studies of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.

STAT6 NCOA1

7.70e-06297214993689
Pubmed

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.

SHANK3 CLK2

7.70e-06297226847545
Pubmed

Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells.

TLR4 IL1R1

7.70e-06297222586037
Pubmed

Ripor2 is involved in auditory hair cell stereociliary bundle structure and orientation.

MYH9 RIPOR2

7.70e-06297230280293
Pubmed

Galectin-8 Downmodulates TLR4 Activation and Impairs Bacterial Clearance in a Mouse Model of Pseudomonas aeruginosa Keratitis.

LGALS8 TLR4

7.70e-06297236603009
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

RIPOR2 AHI1 UGGT1 TUT7 COPB2 FBRS SLFN12 LGR4 ZFP37 STAT6 TLR4 ADAM17 UTRN

1.01e-051084971311544199
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZC3H14 RANBP2 MYH9 KIF1A UGGT1 TUT7 COPB2 UTP20 PRKDC UTRN

1.48e-05653971022586326
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

CYP2E1 TSC2 ODAD2 ARHGEF10L TTLL7 ACAD8 TLR4 TCFL5 FGGY GASK1A TMEM82

1.73e-05814971123251661
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK1 MYH9 UGGT1 TUT7 UTP20 PRKDC

2.27e-0520297633005030
Pubmed

SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms.

TLR4 IL1R1

2.31e-05397215866876
Pubmed

mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression.

TSC2 PRKDC

2.31e-05397224096482
Pubmed

Lipocalin 2 prevents intestinal inflammation by enhancing phagocytic bacterial clearance in macrophages.

LCN2 TLR4

2.31e-05397227734904
Pubmed

Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor.

MYH9 TLR4

2.31e-05397228153611
Pubmed

Effect of miR-495 on lower extremity deep vein thrombosis through the TLR4 signaling pathway by regulation of IL1R1.

TLR4 IL1R1

2.31e-05397230287499
Pubmed

Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance.

STAT6 PRKDC

2.31e-05397211067913
Pubmed

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.

TLR4 IL1R1

2.31e-05397222516259
Pubmed

mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome.

TSC2 IL1R1

2.31e-05397236443301
Pubmed

Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.

BGN TLR4

2.31e-05397224480070
Pubmed

Transcriptional activation by STAT6 requires the direct interaction with NCoA-1.

STAT6 NCOA1

2.31e-05397211574547
Pubmed

Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.

TLR4 IL1R1

2.31e-05397218178857
Pubmed

Dual effects of p38 MAPK on TNF-dependent bronchoconstriction and TNF-independent neutrophil recruitment in lipopolysaccharide-induced acute respiratory distress syndrome.

TLR4 IL1R1

2.31e-05397215972657
Pubmed

α-Intercalated cells defend the urinary system from bacterial infection.

LCN2 TLR4

2.31e-05397224937428
Pubmed

Polymorphisms in the tumor necrosis factor/lipopolysaccharides pathway in Crohn disease in the Jewish Ashkenazi population.

TLR4 ADAM17

2.31e-05397218493210
Pubmed

CD4 positive T helper cells contribute to retinal ganglion cell death in mouse model of ischemia reperfusion injury.

STAT6 PRKDC

2.31e-05397223792169
Pubmed

NOD-scid IL2rγnull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity.

TLR4 PRKDC

2.31e-05397236801998
Pubmed

The role of interleukin-1beta in direct and toll-like receptor 4-mediated neutrophil activation and survival.

TLR4 IL1R1

2.31e-05397215509550
Pubmed

Absence of intestinal PPARγ aggravates acute infectious colitis in mice through a lipocalin-2-dependent pathway.

LCN2 TLR4

2.31e-05397224465207
Pubmed

Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function.

STAT6 TLR4

2.31e-05397216461458
Pubmed

Arthritogenic properties of double-stranded (viral) RNA.

PRKDC IL1R1

2.31e-05397215100310
Pubmed

Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies.

AHI1 SORL1

2.31e-05397218785627
Pubmed

An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.

STAT6 NCOA1

2.31e-05397212138096
Pubmed

Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.

STAT6 NCOA1

2.31e-05397214757047
Pubmed

BGN/TLR4/NF-B Mediates Epigenetic Silencing of Immunosuppressive Siglec Ligands in Colon Cancer Cells.

BGN TLR4

2.31e-05397232050430
Pubmed

Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling.

TLR4 IL1R1

2.31e-05397231228609
Pubmed

Microglial TLR4-dependent autophagy induces ischemic white matter damage via STAT1/6 pathway.

STAT6 TLR4

2.31e-05397230555556
Pubmed

Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.

SIGLEC1 PRKDC

2.31e-05397226429886
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD2 RANBP2 CDC6

3.12e-052297327717094
Pubmed

A murine model of contact lens-associated fusarium keratitis.

TLR4 IL1R1

4.60e-05497219875664
Pubmed

NGF/TRKA Promotes ADAM17-Dependent Cleavage of P75 in Ovarian Cells: Elucidating a Pro-Tumoral Mechanism.

NTRK1 ADAM17

4.60e-05497235216240
Pubmed

Pax6 downregulation mediates abnormal lineage commitment of the ocular surface epithelium in aqueous-deficient dry eye disease.

PRKDC IL1R1

4.60e-05497224143217
Pubmed

The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation.

TLR4 IL1R1

4.60e-05497230033154
Pubmed

A novel anesthesia regime enables neurofunctional studies and imaging genetics across mouse strains.

TSC2 SHANK3

4.60e-05497227080031
Pubmed

Ligand-dependent induction of noninflammatory dendritic cells by anergic invariant NKT cells minimizes autoimmune inflammation.

STAT6 PRKDC

4.60e-05497218684934
Pubmed

The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.

KIF1A NTRK1

4.60e-05497227263974
Pubmed

Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression.

LGR4 TLR4

4.60e-05497223589304
Pubmed

Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.

TLR4 IL1R1

4.60e-05497223708119
Pubmed

CD4+ T cells and IFN-γ are required for the development of Pneumocystis-associated pulmonary hypertension.

STAT6 PRKDC

4.60e-05497224361497
Pubmed

Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.

TSC2 SHANK3

4.60e-05497230237867
Pubmed

ST2/MyD88 Deficiency Protects Mice against Acute Graft-versus-Host Disease and Spares Regulatory T Cells.

TLR4 IL1R1

4.60e-05497230979817
Pubmed

Biglycan is a new high-affinity ligand for CD14 in macrophages.

BGN TLR4

4.60e-05497229777767
Pubmed

P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.

STAT6 NCOA1

4.60e-05497218267973
Pubmed

MyD88 regulation of Fusarium keratitis is dependent on TLR4 and IL-1R1 but not TLR2.

TLR4 IL1R1

4.60e-05497218566426
Pubmed

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages.

BGN TLR4

4.60e-05497216025156
Pubmed

Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling.

TLR4 IL1R1

4.60e-05497222565313
Pubmed

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.

STAT6 TLR4

4.60e-05497215137944
Pubmed

Interactions between leukotriene C4 and interleukin 13 signaling pathways in a mouse model of airway disease.

STAT6 GGT5

4.60e-05497216594735
Pubmed

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways.

ITGAX TLR4

4.60e-05497217916553
Pubmed

TLR4-mediated galectin-1 production triggers epithelial-mesenchymal transition in colon cancer cells through ADAM10- and ADAM17-associated lactate production.

TLR4 ADAM17

4.60e-05497227837433
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK1 TANC2 ZC3H14 UGGT1 COPB2 ARHGEF17 ARHGEF10L TOMM40 PPIH UTRN SORL1

5.04e-05916971132203420
Pubmed

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.

LGR4 LCN2 STAT6 TLR4 ADAM17

5.75e-0514697529688375
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

RANBP2 KIF1A EARS2 TUT7 COPB2 TSC2 CACHD1 CTPS2 MTR UTP20 PRKDC

6.48e-05942971131073040
Pubmed

Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues.

KERA BGN

7.66e-05597218620607
Pubmed

The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly.

KERA BGN

7.66e-05597223331954
Pubmed

MyD88 is required for the formation of long-term humoral immunity to virus infection.

PRKDC IL1R1

7.66e-05597217404295
Pubmed

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.

BGN TLR4

7.66e-05597219605353
Pubmed

Inflammatory mediators gene polymorphisms in preeclampsia.

TLR4 IL1R1

7.66e-05597220818961
Pubmed

The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo.

TLR4 IL1R1

7.66e-05597214978111
Pubmed

Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy.

DRP2 UTRN

7.66e-05597211430802
Pubmed

De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways.

BGN TLR4

7.66e-05597224361484
Pubmed

Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment.

SIGLEC1 IL1R1

7.66e-05597233621212
Pubmed

Toll-like receptor 4 protects against lethal Leptospira interrogans serovar icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden.

TLR4 PRKDC

7.66e-05597216428731
Pubmed

Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin.

TLR4 IL1R1

7.66e-05597216272344
Pubmed

Compartment-specific and sequential role of MyD88 and CARD9 in chemokine induction and innate defense during respiratory fungal infection.

TLR4 IL1R1

7.66e-05597225621893
Pubmed

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

BGN TLR4

7.66e-05597221084753
Pubmed

The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis.

BGN TLR4

7.66e-05597222095710
Pubmed

Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study.

TOMM40 DNAH11

7.66e-05597224468470
Pubmed

Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis.

TLR4 IL1R1

7.66e-05597231507610
Pubmed

Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.

TLR4 IL1R1

7.66e-05597222307620
Pubmed

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis.

TLR4 IL1R1

7.66e-05597230650348
Pubmed

Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rγnull mice is attributed to a lack of CD11c+B220+CD122+ cells.

ITGAX PRKDC

7.66e-05597223018460
Pubmed

β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function.

TLR4 PRKDC

7.66e-05597236868208
Pubmed

Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling.

TLR4 PRKDC

7.66e-05597223223360
Pubmed

Arthritis induced with cartilage-specific antibodiesis IL-4-dependent.

STAT6 IL1R1

7.66e-05597216688680
Pubmed

The importance of IL-1 beta and TNF-alpha, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis.

PRKDC IL1R1

7.66e-05597212133972
Pubmed

Pepsin digest of wheat gliadin fraction increases production of IL-1β via TLR4/MyD88/TRIF/MAPK/NF-κB signaling pathway and an NLRP3 inflammasome activation.

TLR4 IL1R1

7.66e-05597223658628
Pubmed

Ablation of TrkA function in the immune system causes B cell abnormalities.

NTRK1 PRKDC

7.66e-05597215459109
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

NTRK1 SOCS6 TNNI3K CLK2 TRIM56 ARMC5 STK38L

8.52e-0537297722939624
Pubmed

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.

LGR4 KERA BGN

1.08e-043397318424556
Pubmed

Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner.

TLR4 IL1R1

1.15e-04697233123170
Pubmed

Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses.

TLR4 IL1R1

1.15e-04697218295350
Pubmed

SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype.

TLR4 IL1R1

1.15e-04697226590148
Pubmed

Expression of the dystrophin-related protein 2 (Drp2) transcript in the mouse.

DRP2 UTRN

1.15e-0469729245586
Pubmed

The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice.

TLR4 IL1R1

1.15e-04697228875549
Pubmed

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.

TLR4 IL1R1

1.15e-04697224807222
GeneFamilySmall leucine rich repeat proteoglycans

KERA BGN PRELP

1.09e-0512683573
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DRP2 ZSWIM2 UTRN

3.99e-051868391
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TANC2 RGPD2 RANBP2 TTC31

9.25e-04115684769
GeneFamilyCyclophilin peptidylprolyl isomerases

RANBP2 PPIH

2.29e-0319682909
CoexpressionAtlasJC_hmvEC_top-relative-expression-ranked_2500_k-means-cluster#1

TCAF2 MYH9 ABCA3 DRP2 LRRC32 SLFN12 CAV2 SHANK3 BGN GGT5 CFAP54 ZFHX4 TLR4 TNFAIP2 TRIM47 UTRN

3.75e-069369516JC_hmvEC_2500_K1
ToppCellCerebellum-Endothelial|Cerebellum / BrainAtlas - Mouse McCarroll V32

MYH9 LRRC32 CAV2 STAT6 GGT5 TRIM56 TRIM47 UTRN

1.12e-081959782192fd9b4682054776f0716933aed5a4a9412657
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRRC32 LGR4 CACHD1 BGN LRRC3 CDC6 TRIM47

8.30e-08167977f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRRC32 LGR4 CACHD1 BGN LRRC3 CDC6 TRIM47

8.30e-081679775fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYH9 LRRC32 BGN STAT6 TRIM56 TRIM47 UTRN

1.93e-07189977ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC32 F8 SHANK3 GGT5 TLR4 IL1R1 UTRN

2.64e-07198977259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCellMyeloid-Myeloid-E_(Neutrophils)|Myeloid / shred on cell class and cell subclass (v4)

RIPOR2 TUT7 LCN2 GGT5 TREML2 SORL1

9.56e-071509761bffb8d86b737ac43be902d9468041aef3542f1f
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 LCN2 TNFAIP2 TREML2 SORL1 DNAH11

9.94e-071519765893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 LCN2 TNFAIP2 TREML2 SORL1 DNAH11

9.94e-07151976771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCellfacs-Lung-EPCAM-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 LCN2 GGT5 TNFAIP2 TREML2 SORL1

1.39e-06160976b73f07a0088936fbc3656a05710a67f38b4ae551
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 LCN2 GGT5 TNFAIP2 TREML2 SORL1

1.39e-06160976b88876a58fea2066468e74dcc439c8561130a910
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH9 ARHGEF17 BGN GGT5 ZNF320 PRELP

2.34e-0617597612f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellsevere-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RIPOR2 ITGAX GGT5 TNFAIP2 PRKDC SORL1

2.50e-06177976d1ad35ee3d2a84b1d01126d0a38464ab858c00d0
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

RANBP2 UGGT1 PSMD5 CAV2 CAPN8 CLK2

2.58e-061789769a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 ODAD2 LRRC43 CFAP54 DLEC1 DNAH11

3.33e-06186976f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAV2 F8 SHANK3 BGN TTLL7 PRELP

3.54e-061889760aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCellSubstantia_nigra-Endothelial|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYH9 LRRC32 BGN PRELP IL1R1 TRIM47

3.65e-06189976bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCellIPF-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

LCN2 ARHGEF10L GGT5 CAPN8 TNFAIP2 IL1R1

3.88e-06191976267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 LRRC32 ARHGEF17 BGN GGT5 PRELP

4.00e-0619297609cb5b89a164ac7444774ccc8c90323c8ea2026b
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC32 F8 SHANK3 BGN TTLL7 PRELP

4.12e-06193976826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC32 F8 SHANK3 BGN TTLL7 PRELP

4.12e-0619397687d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 CACHD1 ODAD2 CFAP54 DLEC1 DNAH11

4.12e-06193976ea345d34440b25f65358a53dc72831998d1c3620
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC32 F8 SHANK3 BGN TTLL7 PRELP

4.12e-06193976d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 LRRC32 ARHGEF17 BGN GGT5 PRELP

4.12e-06193976dd4bac8a93a5b9dcf7301f1d7d6e3eb6670f5c68
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 LRRC32 ARHGEF17 BGN GGT5 PRELP

4.12e-061939762ddf9b2770a0be9689e01d1a3d19e4a6d42c7a50
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH9 RIPOR2 LRRC32 ARHGEF17 BGN GGT5

4.24e-061949767a7406c3b021aeafde423d20290c681c3e8ea0a6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ARHGEF10L CAPN8 ZFHX4 MTR SORL1

4.50e-06196976c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAV2 ARHGEF17 BGN TTLL7 PRELP UTRN

4.63e-0619797602e70768a917c5f097bc653e9e965a1000289d2e
ToppCellstromal_cell|World / Lineage and Cell class

CAV2 BGN GGT5 ZFHX4 PRELP IL1R1

4.91e-06199976507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCellstromal_cell-stromal_cell|World / Lineage and Cell class

CAV2 BGN GGT5 ZFHX4 PRELP IL1R1

4.91e-0619997674262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell(06)_OLFM4+|World / shred by cell type by condition

TANC2 LCN2 LGALS8 TNFAIP2 IL1R1 SORL1

4.91e-06199976c773b9180dbfec9c19d4098dd43332e6f6050372
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA3 ITGAX STAT6 CAPN8 SIGLEC1 UTRN

4.91e-06199976155b03b859157013e9142e9248551369127d9204
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TUT7 SOCS6 ITGAX TLR4 SIGLEC1 SORL1

4.91e-06199976e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCellControl-Control-Myeloid-Neutrophil|Control / Disease, condition lineage and cell class

MYH9 ITGAX TLR4 TNFAIP2 IL1R1 SORL1

5.05e-0620097695c41f147a1594d49e73cb56d86d301c3115ce20
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ODAD2 LRRC43 CFAP54 DLEC1 DNAH11

5.05e-0620097631d75c26055177d656df1fbb10b764cebd61e122
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ODAD2 LRRC43 CFAP54 DLEC1 DNAH11

5.05e-0620097685c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CAV2 BGN STAT6 GGT5 PRELP TLR4

5.05e-06200976aafe594c88710f8c53d59667cdac5035e08f5511
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ODAD2 LRRC43 CFAP54 DLEC1 DNAH11

5.05e-06200976e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ODAD2 LRRC43 CFAP54 DLEC1 DNAH11

5.05e-0620097612bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CAV2 BGN STAT6 GGT5 PRELP TLR4

5.05e-06200976a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Otof_(Layer_2/3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTX4 CDHR2 LRRC43 TCFL5

5.48e-0653974a41f66edf468f824494a922c3addf429a9125b7f
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTX4 CDHR2 ODAD2 LRRC43 TCFL5

6.57e-06120975a6d0406a174d46ce06b41280292931954af88a59
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

2.00e-051519758216462e723fec2797387929dde095370947e10a
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD2 LRRC43 CFAP54 DLEC1 DNAH11

2.20e-051549759ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD2 LRRC43 CFAP54 DLEC1 DNAH11

2.20e-0515497558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellfacs-Lung-24m-Hematologic-myeloid-neutrophil|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

2.41e-05157975e96241db2b5ff52b230e3e33207e7bb968900cab
ToppCellfacs-Lung-24m-Hematologic-myeloid-neutrophil-neutrophil|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

2.41e-0515797507a0f8d29a3111be670eae030a91474465eba734
ToppCellfacs-Lung-nan-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

2.57e-05159975836c4b5f9a714ffb5a449087ebefdbb37dd3a2a9
ToppCelldroplet-Lung-1m-Hematologic-myeloid-neutrophil-neutrophil|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

2.57e-05159975be54b910ccb73e37eb81945bbad9a89d2bcec34b
ToppCelldroplet-Lung-1m-Hematologic-myeloid-neutrophil|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

2.57e-05159975178678173b005cb8225472306657f0d8289b133b
ToppCellfacs-Lung-nan-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

2.57e-05159975a6742ba2216427409173aec4e05a537d7fde226c
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 KIF1A TTLL7 CFAP54 DNAH11

2.98e-05164975fd30c55d0d75ef8b9396435d836187168095152b
ToppCellfacs-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

3.15e-051669753195035445d35d820f5e00dd03b029730478b024
ToppCellfacs-Lung-3m-Hematologic-myeloid-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RIPOR2 LCN2 GGT5 TNFAIP2 SORL1

3.15e-051669756b6ecd70264b6bfbd8a3a378c965702829e2ecf1
ToppCell3'_v3-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

NTRK1 SOCS6 CAV2 TTLL7 CTPS2

3.53e-051709754dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

CFAP47 LRRC43 CFAP54 TRIM56 DLEC1

3.63e-0517197574be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCelldroplet-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAV2 LCN2 PRELP TRIM47 GASK1A

3.63e-0517197592ac4cc3d54da2ea8e202aa59c78e8875356649e
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DLGAP2 BICRA F8 TLR4 UTRN

4.06e-0517597543be63976da5ad0764d24d90919a77ce46068f52
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RGPD2 MYH9 NTRK1 ANKRD27 STK38L

4.17e-05176975581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAV2 ARHGEF17 BGN UTRN DNAH11

4.28e-051779754943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAV2 ARHGEF17 BGN UTRN DNAH11

4.28e-051779753f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|metastatic_Brain / Location, Cell class and cell subclass

LRRC32 BGN GGT5 ZFHX4 PRELP

4.28e-0517797554f39be5d90363cfd44dea1a96ae06d3143aa795
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 TUT7 SLFN12 TTLL7 UTRN

4.40e-0517897501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

4.40e-05178975de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RGPD2 DLGAP2 KIF1A PRELP IL1R1

4.40e-05178975a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIPOR2 NTRK1 TRPC5 ITGAX SORL1

4.52e-05179975de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACHD1 TTLL7 DLEC1 TRIM47 UTRN

4.52e-05179975a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIPOR2 NTRK1 TRPC5 ITGAX SORL1

4.52e-05179975def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCellControl-Stromal-SMC|Control / Disease state, Lineage and Cell class

LRRC32 CAV2 ARHGEF17 BGN PRELP

4.52e-051799751378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

ITGAX BGN TLR4 SIGLEC1 TNFAIP2

4.64e-051809757be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F8 SHANK3 BGN TTLL7 PRELP

4.64e-05180975dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRRC43 TTLL7 CFAP54 DLEC1 DNAH11

4.64e-0518097592fb01b91261b3103454924cde56add337b41844
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F8 SHANK3 BGN TTLL7 PRELP

4.64e-05180975423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC32 ODAD2 BGN CFAP54 PRELP

4.76e-05181975c1b1e62440805800a3a600b1ddd79be1c9762598
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

4.76e-05181975dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZSWIM2 CAV2 SHANK3 TLR4 UTRN

4.89e-0518297563b41b538b26bc899558807fd035e543611f8c52
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

4.89e-051829757ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

4.89e-05182975fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 CAV2 BGN TRIM47 UTRN

4.89e-05182975c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 CAV2 BGN TRIM47 UTRN

4.89e-05182975d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl_(Layer_2/3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CDHR2 ODAD2 LRRC43 TCFL5

4.90e-0592974dfe63bb979f0382163955b32909ffab1de37685a
ToppCellsevere-Myeloid-Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RIPOR2 ITGAX TNFAIP2 IL1R1 SORL1

5.02e-0518397560a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 PTX4 ODAD2 LRRC43 DNAH11

5.02e-051839756ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 PTX4 ODAD2 LRRC43 DNAH11

5.02e-0518397518040d0653286071df959513c63d94b555a5d00a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 ODAD2 CAPN8 ZFHX4 DNAH11

5.15e-051849752cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM2 ODAD2 LRRC43 TRIM56 DNAH11

5.15e-05184975264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 ODAD2 CAPN8 ZFHX4 DNAH11

5.15e-05184975ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 ODAD2 CAPN8 ZFHX4 DNAH11

5.15e-051849752b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM2 ODAD2 LRRC43 TRIM56 DNAH11

5.15e-05184975d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellControl-Stromal-SMC|World / Disease state, Lineage and Cell class

LRRC32 CAV2 ARHGEF17 BGN PRELP

5.15e-0518497588b1a4c9a96a99fc3a39f7a2c3d0838739606f3e
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM2 ODAD2 LRRC43 TRIM56 DNAH11

5.15e-0518497522010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

5.15e-051849755daff849625f2f41d56615569c0ed59cd733b34c
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

LRRC32 KERA BGN PRELP IL1R1

5.28e-05185975e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

5.28e-051859755e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

5.28e-0518597530f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

5.28e-051859753e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

5.28e-0518597518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

5.42e-0518697585787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC32 CAV2 F8 BGN TNFAIP2

5.56e-05187975f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

LRRC32 F8 SHANK3 CFAP54 UTRN

5.56e-0518797540ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 ODAD2 CFAP54 DLEC1 DNAH11

5.56e-051879759e10ed56090d82589bc457788282f664b70ace4b
Diseasepulpitis (biomarker_via_orthology)

TLR4 IL1R1

3.07e-053952DOID:11121 (biomarker_via_orthology)
Diseasehereditary sensory neuropathy (is_implicated_in)

KIF1A NTRK1

6.13e-054952DOID:0050548 (is_implicated_in)
Diseasetype 2 diabetes mellitus (is_marker_for)

AHI1 CYP2E1 LCN2 F8 TLR4

8.03e-05136955DOID:9352 (is_marker_for)
Diseaseautism spectrum disorder (implicated_via_orthology)

ABCA3 TRPC5 TSC2 SHANK3 CHD6

1.35e-04152955DOID:0060041 (implicated_via_orthology)
Diseaseurinary tract infection (is_implicated_in)

LCN2 TLR4

1.53e-046952DOID:0080784 (is_implicated_in)
DiseaseDrug toxicity

CYP2E1 LCN2 MTR ABCC12

1.60e-0484954C0013221
DiseaseAdverse reaction to drug

CYP2E1 LCN2 MTR ABCC12

1.60e-0484954C0041755
Diseasemyocarditis (biomarker_via_orthology)

LCN2 STAT6

2.13e-047952DOID:820 (biomarker_via_orthology)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

DRP2 CAPN8 UTRN

2.14e-0436953DOID:11723 (implicated_via_orthology)
Diseaselow tension glaucoma (is_implicated_in)

CAV2 TLR4

2.84e-048952DOID:13544 (is_implicated_in)
Diseasecognitive decline measurement, memory performance, language measurement

MYH9 TNFAIP2

5.54e-0411952EFO_0004874, EFO_0007710, EFO_0007797
Diseaseinsomnia measurement

TANC2 ARHGEF10L TNNI3K TLR4 GASK1A SORL1 DNAH11

5.82e-04443957EFO_0007876
DiseaseAL amyloidosis

FBRS DNAH11

6.63e-0412952MONDO_0019438
DiseaseAlzheimer's disease (is_implicated_in)

NTRK1 TLR4 ADAM17 SORL1

8.89e-04132954DOID:10652 (is_implicated_in)
DiseaseKartagener syndrome (implicated_via_orthology)

ODAD2 DNAH11

9.10e-0414952DOID:0050144 (implicated_via_orthology)
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

LCN2 STAT6

9.10e-0414952DOID:898 (is_marker_for)
Diseasecholesteatoma of middle ear (is_marker_for)

TLR4 IL1R1

1.20e-0316952DOID:10964 (is_marker_for)
Diseaseglaucoma (implicated_via_orthology)

NTRK1 LGR4

1.35e-0317952DOID:1686 (implicated_via_orthology)
Diseaserenal fibrosis (implicated_via_orthology)

STAT6 TLR4

1.35e-0317952DOID:0050855 (implicated_via_orthology)
Diseasefasting blood insulin measurement

COPB2 ACAD8 FGGY

1.45e-0369953EFO_0004466
Diseasechildhood trauma measurement, alcohol consumption measurement

TANC2 DLGAP2 PCDHGB3

1.58e-0371953EFO_0007878, EFO_0007979
DiseaseAutistic Disorder

DLGAP2 AHI1 KIF1A TSC2 SHANK3

1.58e-03261955C0004352
DiseaseHIV-1 infection, Susceptibility to viral and mycobacterial infections

BICRA ADAM17

2.07e-0321952EFO_0000180, Orphanet_391311
DiseaseLung Injury

NTRK1 TLR4

2.07e-0321952C0273115
DiseaseChronic Lung Injury

NTRK1 TLR4

2.07e-0321952C2350344
DiseaseKidney Failure

MYH9 TLR4

2.27e-0322952C0035078
DiseaseRheumatoid Arthritis

CAV2 LCN2 BGN TNFAIP2

2.45e-03174954C0003873
Diseaseprimary open angle glaucoma (is_implicated_in)

CAV2 TLR4

2.48e-0323952DOID:1070 (is_implicated_in)
DiseaseSensorineural Hearing Loss (disorder)

MYH9 RIPOR2

2.48e-0323952C0018784
Diseaselate-onset Alzheimers disease

BICRA ADAM17 DLEC1 TOMM40 SORL1

2.57e-03292955EFO_1001870
DiseaseDyslipidemias

TOMM40 DNAH11

2.70e-0324952C0242339
DiseaseDyslipoproteinemias

TOMM40 DNAH11

2.70e-0324952C0598784
Diseaseuveitis (biomarker_via_orthology)

LCN2 TLR4

2.93e-0325952DOID:13141 (biomarker_via_orthology)
DiseaseNeoplasm Invasiveness

MYH9 CYP2E1 TLR4 SORL1

3.00e-03184954C0027626

Protein segments in the cluster

PeptideGeneStartEntry
FKPANHRGQLEISSL

ARHGEF10L

576

Q9HCE6
PVHDFLKRRNESLLG

CFAP54

1361

Q96N23
RDHLNVRKQFGEPLA

ACAD8

296

Q9UKU7
RIPNKHLFSLNAGER

AHI1

596

Q8N157
KRLTLGEALQHPFFA

CLK2

466

P49760
PEHRFELALQLGELK

COPB2

641

P35606
RLDLLGQPSACLHFK

CACHD1

631

Q5VU97
LLNGLHLSPQAELDF

DNAH11

266

Q96DT5
ENTLRGLLLEPHANK

ABCA3

1496

Q99758
HFLLDSGLQLPAQRA

ARMC5

751

Q96C12
LLDQFEKQLPLHRDG

DLGAP2

191

Q9P1A6
DRLPTKNGQLLFLHS

CAPN8

156

A6NHC0
TLRAQEKHGLQPALL

RANBP2

561

P49792
ADENFKLRHSAPGLL

PPIH

96

O43447
AHFLLEALRKTQGQP

CYP2E1

151

P05181
LGLKAHCENFNLLLP

ITGAX

706

P20702
RNFHLDPKLADILSP

ARHGEF17

901

Q96PE2
RADLIPLLLKHGANA

ANKRD27

756

Q96NW4
DLNRFLRSHGPDAKL

NTRK1

596

P04629
GKSKDIALHLNPRLN

LGALS8

221

O00214
AELRKHNLDGPRLAA

NLRP10

431

Q86W26
LDANKISHLPDGAFQ

LRRC3

71

Q9BY71
ELHLDNNKLARVPSG

BGN

281

P21810
GPQSLDDKLRLHSRQ

FAM205A

1291

Q6ZU69
LQLAGNDLSFIHPKA

LGR4

86

Q9BXB1
RAHGPALLTKDNALF

F8

996

P00451
GKLDPHLVLDQLRCN

MYH9

681

P35579
PHFSLIQKENLDGSR

PCDHGB3

176

Q9Y5G1
RENKLLHFPDLAALP

LRRC32

251

Q14392
NFIRFSKSLGLPENH

LCN2

171

P80188
NDLLKFIRPLHEGTL

FAM3A

131

P98173
AGNLQHPEDKLNFRL

GASK1A

486

Q9UFP1
HNFSLDPDTGLLRNL

CDHR2

631

Q9BYE9
GDSHKLDFRNDLLPC

FBRS

106

Q9HAH7
LTRNDFGHPTLKLQD

BPIFC

146

Q8NFQ6
SGLPKDIDRLHNLRA

DOCK1

266

Q14185
LRGFLPENKFNHTLA

CHD6

2416

Q8TD26
DFHGNRSPLADLTLK

FGGY

391

Q96C11
SHPKLQNASRDLLGE

GGT5

341

P36269
RKRLGDDNLCNTPHL

CDC6

56

Q99741
PQALNDFLHGSEKLD

BICRA

16

Q9NZM4
DPHRLNSHLKLGFED

CAV2

41

P51636
RLQDFAVGPLKLDLH

DLEC1

1446

Q9Y238
LSNPKDRGLHLEVQL

CFAP47

2571

Q6ZTR5
PLLLDNIHFSGVKDR

IL1R1

166

P14778
RLEAFSDHSGKLQLP

DRP2

96

Q13474
PLDAALDHLRLGNTF

KIF1A

986

Q12756
SPNEKHLFRGLSLNG

LRRC43

286

Q8N309
LEPLRQKLAALQGAH

PRSS56

476

P0CW18
NDNKLVLHGRDSLLP

PTX4

321

Q96A99
RSKGRNEQFPVLDHL

UTP20

486

O75691
RLKQLQEAHRDFGPS

UTRN

2791

P46939
SNLLLGFDRSHPNKQ

SORL1

216

Q92673
FPDGLQLRKNHTLSE

TRIM47

61

Q96LD4
RNIPFTHLDNILKSG

TREML2

131

Q5T2D2
QLGFIHRDIKPDNLL

STK38L

206

Q9Y2H1
DLLQHKRPELSLGNK

TDRD15

206

B5MCY1
NLKDLCPLLSEHGLQ

TCAF2

306

A6NFQ2
TLRAQEKHGLQPALL

RGPD2

561

P0DJD1
KFQLERDLCPHLGQI

SPATA31A6

656

Q5VVP1
KPLDSGLLHNNDRLS

NCOA1

606

Q15788
RLHGGLKPLASLLNN

ODAD2

711

Q5T2S8
FLRLNHNKLSDEGLP

KERA

241

O60938
FKDHARPLKGNNDIL

MTR

56

Q99707
HADKNGRTPLDLAAF

TANC2

1161

Q9HCD6
DLQHNRLSDGVFKPD

PRELP

201

P51888
AKLIHNLRGLQFKDP

ABCC12

696

Q96J65
FAHLPLLLNRDGSKL

EARS2

271

Q5JPH6
DAFNGLLLALEPHKE

RIPOR2

606

Q9Y4F9
FGPHQRLEKLDSLLS

ADAM17

26

P78536
FKERLHLPIGDSASN

CTPS2

266

Q9NRF8
QLGLDPNFLRHSQFK

ZFHX4

2071

Q86UP3
GFDTLLQNLHEDLKP

TNFAIP2

461

Q03169
RSLLAEHQKIPFGDN

ZNF320

481

A2RRD8
LPAQLDGDLRFHALR

NEURL1

286

O76050
VARLLDKGLDPNFHD

SHANK3

131

Q9BYB0
NRGLLPEHFLFLAQK

STAT6

466

P42226
TPENLCRKLFLQHEG

SLFN12

391

Q8IYM2
GNPEHRVCNLLLKDL

SIGLEC1

91

Q9BZZ2
FLQEGAPHRTLNLLL

TMEM82

141

A0PJX8
LALHPNAFKRLGASL

PRKDC

1066

P78527
PLTLALGAFLNHRKN

TOMM40

336

O96008
KFKLPRNHESALQLG

ZSWIM2

86

Q8NEG5
LGPLFSLLNENHREK

PSMD5

46

Q16401
EVLDLLGNRKHPRSF

TRPC5

756

Q9UL62
PFDLNHNLGAGLSRK

TUT7

1281

Q5VYS8
DRPLHLASAKGFLNI

TNNI3K

201

Q59H18
LEAAKHQDIGLPRAF

TCFL5

286

Q9UL49
TKNLDLSFNPLRHLG

TLR4

56

O00206
LHLLSRQLEDPNGSF

ZC3H14

566

Q6PJT7
GKILKQNLDLPDHSR

ZFP37

181

Q9Y6Q3
PALNGVRKDFHDLQS

SOCS6

166

O14544
LFGKLRDLHPDLEGQ

UGGT1

286

Q9NYU2
SLIRNGDKLPSQDHL

TTLL7

171

Q6ZT98
LRADSLHRLGLPNKD

TSC2

621

P49815
PGLLDKNCHLLRLSF

TRIM56

356

Q9BRZ2
DPQQADILGALKHLR

TMEM260

681

Q9NX78
ALKLNPQDHRLFGNR

TTC31

331

Q49AM3