Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B LGALS9

7.10e-0671193GO:0048030
GeneOntologyMolecularFunctiongalactoside binding

LGALS9C LGALS9B LGALS9

1.69e-0591193GO:0016936
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9C LGALS9B LGALS9

2.18e-04201193GO:0070492
GeneOntologyMolecularFunctiontubulin binding

TTLL9 EML6 LRRK2 KIF16B MAST2 NME8 SIRT2 EML5 BRCA2 AGBL1

2.45e-0442811910GO:0015631
GeneOntologyMolecularFunctionintegrin binding involved in cell-matrix adhesion

ITGA9 SVEP1

3.48e-0451192GO:0098640
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

CHRNA6 OR5M9 HTR2B FPR1 GPR84 GRID2 CHRNB3 OR10D3 LHCGR CELSR1 OR4C15 MS4A2 OR6C1 TLR3 OR4K5 TAS2R31 TAS2R43 TAS2R46 OR4K15

3.99e-04135311919GO:0004888
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

KCNA1 KCNA2

5.20e-0461192GO:1905030
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R31 TAS2R43 TAS2R46

5.44e-04271193GO:0033038
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNA1 KCNA2 KCNC3

6.06e-04281193GO:0005251
GeneOntologyMolecularFunctionNAD-dependent protein lysine deacetylase activity

SIRT5 SIRT2

7.25e-0471192GO:0034979
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5M9 HTR2B FPR1 GPR84 OR10D3 LHCGR CELSR1 OR4C15 OR6C1 OR4K5 TAS2R31 TAS2R43 TAS2R46 OR4K15

7.91e-0488411914GO:0004930
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R31 TAS2R43 TAS2R46

9.88e-04331193GO:0008527
GeneOntologyMolecularFunctioncell-matrix adhesion mediator activity

ITGA9 SVEP1

1.23e-0391192GO:0098634
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

7.27e-0741183GO:0043322
GeneOntologyBiologicalProcessnegative regulation of leukocyte degranulation

LGALS9C LGALS9B LGALS9 FOXF1

2.29e-06171184GO:0043301
GeneOntologyBiologicalProcessregulation of natural killer cell differentiation

LGALS9C LGALS9B LGALS9 RASGRP1

5.65e-06211184GO:0032823
GeneOntologyBiologicalProcessregulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

1.00e-0581183GO:0043321
GeneOntologyBiologicalProcessregulation of leukocyte degranulation

LGALS9C LGALS9B LGALS9 MS4A2 FOXF1

3.04e-05631185GO:0043300
GeneOntologyBiologicalProcessnegative regulation of regulated secretory pathway

LGALS9C LGALS9B LGALS9 FOXF1

3.23e-05321184GO:1903306
GeneOntologyBiologicalProcessleukocyte degranulation

LGALS9C LGALS9B LGALS9 RASGRP1 MS4A2 FOXF1

3.67e-051081186GO:0043299
GeneOntologyBiologicalProcessregulated exocytosis

LGALS9C LGALS9B LRRK2 LGALS9 RASGRP1 MS4A2 PLEK CADPS2 FOXF1

4.57e-052911189GO:0045055
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

RHBDD1 DPY19L2 LRRK2 ETV5 NR3C1 MAST2 NCAPH ADAM28 ADCY7 NME8 LGALS9 ACTL7A LHCGR SIRT2 BRCA2 CFAP221 PARN PRMT7 DPY19L2P2

4.64e-05119411819GO:0048609
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

LGALS9C LGALS9B LGALS9 RASGRP1

5.81e-05371184GO:0033081
GeneOntologyBiologicalProcessnatural killer cell differentiation

LGALS9C LGALS9B LGALS9 RASGRP1

6.46e-05381184GO:0001779
GeneOntologyBiologicalProcessregulation of leukocyte mediated immunity

LGALS9C LGALS9B ATAD5 SVEP1 LGALS9 RASGRP1 MS4A2 TLR3 FOXF1

7.25e-053091189GO:0002703
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

7.90e-05151183GO:2000562
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9C LGALS9B LGALS9

7.90e-05151183GO:0032815
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

LGALS9C LGALS9B LRRK2 LGALS9

9.63e-05421184GO:0043032
GeneOntologyBiologicalProcessreceptor clustering

LGALS9C LGALS9B ETV5 LGALS9 FARP1

1.14e-04831185GO:0043113
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor production

LGALS9C LGALS9B LRRK2 LGALS9 RASGRP1 TLR3

1.17e-041331186GO:0032760
GeneOntologyBiologicalProcessregulation of oxidoreductase activity

LGALS9C HTR2B LGALS9B SIRT5 LGALS9

1.21e-04841185GO:0051341
GeneOntologyBiologicalProcessnegative regulation of exocytosis

LGALS9C LGALS9B LGALS9 FOXF1

1.27e-04451184GO:0045920
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor superfamily cytokine production

LGALS9C LGALS9B LRRK2 LGALS9 RASGRP1 TLR3

1.38e-041371186GO:1903557
GeneOntologyBiologicalProcesspositive regulation of oxidoreductase activity

LGALS9C HTR2B LGALS9B LGALS9

1.38e-04461184GO:0051353
GeneOntologyBiologicalProcessnatural killer cell degranulation

LGALS9C LGALS9B LGALS9

1.40e-04181183GO:0043320
GeneOntologyBiologicalProcessgamete generation

RHBDD1 DPY19L2 LRRK2 ETV5 MAST2 NCAPH ADAM28 NME8 ACTL7A LHCGR SIRT2 BRCA2 CFAP221 PARN PRMT7 DPY19L2P2

1.50e-0498211816GO:0007276
GeneOntologyBiologicalProcesssexual reproduction

RHBDD1 DPY19L2 ADAM21 LRRK2 ETV5 MAST2 NCAPH PKDREJ ADAM28 NME8 ACTL7A LHCGR SIRT2 BRCA2 UBE3A CFAP221 PARN PRMT7 DPY19L2P2

1.61e-04131211819GO:0019953
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

1.65e-04191183GO:0046642
GeneOntologyBiologicalProcesspositive regulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

1.65e-04191183GO:1900426
GeneOntologyBiologicalProcessregulation of T cell chemotaxis

LGALS9C LGALS9B LGALS9

1.94e-04201183GO:0010819
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated immunity

LGALS9C LGALS9B SVEP1 LGALS9 FOXF1

2.27e-04961185GO:0002704
GeneOntologyBiologicalProcessdetection of stimulus

OR5M9 PKDREJ WDR47 OR10D3 KCNA1 OR4C15 OR6C1 OR4K5 TAS2R31 TAS2R43 TAS2R46 OR4K15 FOXF1

2.52e-0472211813GO:0051606
GeneOntologyBiologicalProcessregulation of CAMKK-AMPK signaling cascade

MYH7B LRRK2

3.21e-0451182GO:1905289
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR5M9 HTR2B FPR1 LRRK2 GPR84 ADCY2 ADCY7 OR10D3 LHCGR CELSR1 OR4C15 MS4A2 OR6C1 OR4K5 TAS2R31 TAS2R43 PLEK TAS2R46 OR4K15

3.50e-04139511819GO:0007186
GeneOntologyBiologicalProcessregulation of regulated secretory pathway

LGALS9C LGALS9B LRRK2 LGALS9 MS4A2 FOXF1

3.77e-041651186GO:1903305
GeneOntologyBiologicalProcessregulation of exocytosis

LGALS9C LGALS9B LRRK2 LGALS9 MS4A2 CADPS2 FOXF1

3.91e-042331187GO:0017157
GeneOntologyBiologicalProcessregulation of natural killer cell activation

LGALS9C LGALS9B LGALS9 RASGRP1

4.13e-04611184GO:0032814
GeneOntologyBiologicalProcessregulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

4.31e-04261183GO:1900424
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

LGALS9C LGALS9B GRID2 LGALS9

4.67e-04631184GO:0007157
GeneOntologyBiologicalProcesspeptidyl-tryptophan modification

DPY19L2 DPY19L2P2

4.80e-0461182GO:0018211
GeneOntologyBiologicalProcessprotein C-linked glycosylation via tryptophan

DPY19L2 DPY19L2P2

4.80e-0461182GO:0018317
GeneOntologyBiologicalProcessprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

DPY19L2 DPY19L2P2

4.80e-0461182GO:0018406
GeneOntologyBiologicalProcessprotein C-linked glycosylation

DPY19L2 DPY19L2P2

4.80e-0461182GO:0018103
GeneOntologyBiologicalProcessmyeloid leukocyte activation

LGALS9C LGALS9B LRRK2 LGALS9 RASGRP1 MS4A2 TLR3 FOXF1

5.13e-043201188GO:0002274
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR5M9 WDR47 OR10D3 KCNA1 OR4C15 OR6C1 OR4K5 TAS2R31 TAS2R43 TAS2R46 OR4K15

5.15e-0458211811GO:0050906
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

5.39e-04281183GO:2000561
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

CHRNA6 LRRK2 GRID2 CHRNB3 KCNA1 KCNA2

5.97e-041801186GO:0060078
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

RHBDD1 DPY19L2 ADAM21 LRRK2 ETV5 MAST2 ADAM28 NME8 ACTL7A LHCGR SIRT2 BRCA2 UBE3A CFAP221 TLR3 PRMT7 DPY19L2P2

6.57e-04123511817GO:0003006
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

6.62e-04301183GO:0035739
GeneOntologyBiologicalProcessnegative regulation of mast cell degranulation

LGALS9 FOXF1

6.69e-0471182GO:0043305
GeneOntologyBiologicalProcessdetection of virus

TLR3 SERINC5

6.69e-0471182GO:0009597
GeneOntologyBiologicalProcessregulation of secretion

LGALS9C CHRNA6 RHBDD1 LGALS9B LRRK2 NR3C1 KMO LGALS9 KCNA2 MS4A2 KCNC3 CADPS2 FOXF1

6.74e-0480111813GO:0051046
GeneOntologyBiologicalProcessregulation of lymphocyte chemotaxis

LGALS9C LGALS9B LGALS9

7.30e-04311183GO:1901623
GeneOntologyBiologicalProcesspositive regulation of regulatory T cell differentiation

LGALS9C LGALS9B LGALS9

7.30e-04311183GO:0045591
GeneOntologyBiologicalProcessmast cell degranulation

LGALS9 RASGRP1 MS4A2 FOXF1

8.60e-04741184GO:0043303
GeneOntologyBiologicalProcessT cell chemotaxis

LGALS9C LGALS9B LGALS9

8.79e-04331183GO:0010818
GeneOntologyBiologicalProcesscorpus callosum development

WDR47 KCNA1 KCNA2

8.79e-04331183GO:0022038
GeneOntologyBiologicalProcessexocytosis

LGALS9C LGALS9B LRRK2 LGALS9 RASGRP1 MS4A2 PLEK CADPS2 FOXF1

8.82e-044341189GO:0006887
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

RHBDD1 DPY19L2 ETV5 MAST2 ACTL7A SIRT2 BRCA2 CFAP221 PRMT7 DPY19L2P2

9.02e-0452711810GO:0022412
GeneOntologyBiologicalProcessregulation of natural killer cell mediated cytotoxicity

LGALS9C LGALS9B LGALS9 RASGRP1

9.51e-04761184GO:0042269
GeneOntologyBiologicalProcessmast cell mediated immunity

LGALS9 RASGRP1 MS4A2 FOXF1

9.51e-04761184GO:0002448
GeneOntologyBiologicalProcessactivation of adenylate cyclase activity

ADCY2 ADCY7 LHCGR

9.60e-04341183GO:0007190
GeneOntologyBiologicalProcessmast cell activation involved in immune response

LGALS9 RASGRP1 MS4A2 FOXF1

1.05e-03781184GO:0002279
GeneOntologyBiologicalProcessregulation of secretion by cell

LGALS9C CHRNA6 LGALS9B LRRK2 NR3C1 KMO LGALS9 KCNA2 MS4A2 KCNC3 CADPS2 FOXF1

1.10e-0374011812GO:1903530
GeneOntologyBiologicalProcessspermatogenesis

RHBDD1 DPY19L2 LRRK2 ETV5 MAST2 ADAM28 NME8 ACTL7A LHCGR BRCA2 CFAP221 DPY19L2P2

1.15e-0374411812GO:0007283
GeneOntologyBiologicalProcessregulation of natural killer cell mediated immunity

LGALS9C LGALS9B LGALS9 RASGRP1

1.15e-03801184GO:0002715
GeneOntologyBiologicalProcessestablishment of organelle localization

LRRK2 LGALS9 RASGRP1 SIRT2 MS4A2 BRCA2 ABCE1 CADPS2 NLRP4 FOXF1

1.18e-0354611810GO:0051656
GeneOntologyCellularComponentjuxtaparanode region of axon

SIRT2 KCNA1 KCNA2

3.91e-05121203GO:0044224
GeneOntologyCellularComponentmotile cilium

TTLL9 NME8 ACTL7A GSTM3 CFAP221 DNAI2 TAS2R31 TAS2R43 TAS2R46

2.12e-043551209GO:0031514
GeneOntologyCellularComponentaxonemal dynein complex

DNAI3 NME8 DNAI2

3.87e-04251203GO:0005858
HumanPhenoAbnormal fingertip morphology

LZTR1 NME8 RASGRP1 FAM13A BRCA2 CFAP221 DNAI2 PARN

3.26e-05203338HP:0001211
HumanPhenoClubbing

NME8 RASGRP1 FAM13A BRCA2 CFAP221 DNAI2 PARN

4.08e-05152337HP:0001217
HumanPhenoDecreased fertility

MAGEL2 DPY19L2 NR3C1 NME8 ACTL7A GSTM3 LHCGR BRCA2 CFAP221 DNAI2

9.24e-053803310HP:0000144
HumanPhenoDecreased fertility in males

DPY19L2 NME8 ACTL7A GSTM3 LHCGR BRCA2 CFAP221 DNAI2

9.55e-05236338HP:0012041
HumanPhenoBronchiectasis

NME8 GSTM3 RASGRP1 FAM13A CFAP221 DNAI2 PARN

1.00e-04175337HP:0002110
HumanPhenoInfertility

MAGEL2 DPY19L2 NR3C1 NME8 ACTL7A GSTM3 LHCGR CFAP221 DNAI2

1.18e-04314339HP:0000789
DomainBTB/POZ_dom

LZTR1 KBTBD8 MYNN KCNRG KLHL38 BTBD16 ZBTB39 KCNA1 KCNA2 KCNC3

2.54e-0718511710IPR000210
DomainSKP1/BTB/POZ

LZTR1 KBTBD8 MYNN KCNRG KLHL38 BTBD16 ZBTB39 KCNA1 KCNA2 KCNC3

3.10e-0718911710IPR011333
DomainBTB

LZTR1 KBTBD8 MYNN KCNRG KLHL38 ZBTB39 KCNA1 KCNA2 KCNC3

1.98e-061801179SM00225
DomainBTB

LZTR1 KBTBD8 MYNN KCNRG KLHL38 BTBD16 ZBTB39

6.69e-051601177PS50097
DomainGalectin_CRD

LGALS9C LGALS9B LGALS9

1.03e-04151173IPR001079
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

1.03e-04151173PF00337
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

1.03e-04151173SM00908
DomainGALECTIN

LGALS9C LGALS9B LGALS9

1.03e-04151173PS51304
DomainGLECT

LGALS9C LGALS9B LGALS9

1.03e-04151173SM00276
DomainETS_PEA3_N

ETV1 ETV5

1.16e-0431172IPR006715
DomainETS_PEA3_N

ETV1 ETV5

1.16e-0431172PF04621
DomainBTB

LZTR1 KBTBD8 MYNN KLHL38 BTBD16 ZBTB39

1.76e-041311176PF00651
DomainDUF1908

MAST2 MAST3

2.32e-0441172PF08926
DomainMA_Ser/Thr_Kinase_dom

MAST2 MAST3

2.32e-0441172IPR015022
DomainMAST_pre-PK_dom

MAST2 MAST3

2.32e-0441172IPR023142
Domain-

MAST2 MAST3

2.32e-04411721.20.1480.20
DomainApc4_WD40_dom

EML6 WDR47 EML5

2.53e-04201173IPR024977
DomainANAPC4_WD40

EML6 WDR47 EML5

2.53e-04201173PF12894
Domain-

LGALS9C LGALS9B SVEP1 LGALS9 CELSR1

3.27e-049511752.60.120.200
DomainBTB_2

KCNRG KCNA1 KCNA2 KCNC3

3.38e-04531174PF02214
DomainT1-type_BTB

KCNRG KCNA1 KCNA2 KCNC3

3.38e-04531174IPR003131
DomainTHIOREDOXIN_1

NME8 TXNDC11 TXN

4.98e-04251173PS00194
DomainTAS2R

TAS2R31 TAS2R43 TAS2R46

5.61e-04261173PF05296
DomainT2R

TAS2R31 TAS2R43 TAS2R46

5.61e-04261173IPR007960
DomainWD40_repeat_dom

EML6 LRRK2 DNAI3 WDR47 EML5 DNAI2 WDR82 EIF2A

5.67e-042971178IPR017986
DomainAdcy_conserved_dom

ADCY2 ADCY7

5.74e-0461172IPR009398
DomainHELP

EML6 EML5

5.74e-0461172PF03451
DomainDUF1053

ADCY2 ADCY7

5.74e-0461172PF06327
DomainHELP

EML6 EML5

5.74e-0461172IPR005108
DomainK_chnl_volt-dep_Kv

KCNA1 KCNA2 KCNC3

6.28e-04271173IPR003968
DomainSIR2

SIRT5 SIRT2

8.00e-0471172PF02146
DomainSsirtuin_cat_dom

SIRT5 SIRT2

8.00e-0471172IPR026590
DomainSirtuin

SIRT5 SIRT2

8.00e-0471172IPR003000
DomainSIRTUIN

SIRT5 SIRT2

8.00e-0471172PS50305
DomainThioredoxin

NME8 TXNDC11 TXN

9.48e-04311173PF00085
DomainAC_N

ADCY2 ADCY7

1.06e-0381172IPR032628
DomainAdcy

ADCY2 ADCY7

1.06e-0381172IPR030672
DomainK_chnl_volt-dep_Kv1

KCNA1 KCNA2

1.06e-0381172IPR003972
DomainAC_N

ADCY2 ADCY7

1.06e-0381172PF16214
DomainVG_K_chnl

KCNA1 KCNA2 KCNC3

1.14e-03331173IPR028325
Domain-

EML6 LRRK2 DNAI3 WDR47 EML5 DNAI2 WDR82 EIF2A

1.19e-0333311782.130.10.10
DomainWD40/YVTN_repeat-like_dom

EML6 LRRK2 DNAI3 WDR47 EML5 DNAI2 WDR82 EIF2A

1.24e-033351178IPR015943
DomainWD40

EML6 LRRK2 DNAI3 WDR47 EML5 DNAI2 WDR82

1.50e-032681177SM00320
DomainWD40_repeat

EML6 LRRK2 DNAI3 WDR47 EML5 DNAI2 WDR82

1.63e-032721177IPR001680
DomainWD_REPEATS_1

EML6 DNAI3 WDR47 EML5 DNAI2 WDR82 EIF2A

1.85e-032781177PS00678
DomainWD_REPEATS_2

EML6 DNAI3 WDR47 EML5 DNAI2 WDR82 EIF2A

1.89e-032791177PS50082
DomainWD_REPEATS_REGION

EML6 DNAI3 WDR47 EML5 DNAI2 WDR82 EIF2A

1.89e-032791177PS50294
Domain-

SIRT5 SIRT2

2.06e-031111723.40.50.1220
DomainThioredoxin_domain

NME8 TXNDC11 TXN

2.15e-03411173IPR013766
DomainTHIOREDOXIN_2

NME8 TXNDC11 TXN

2.46e-03431173PS51352
DomainDHS-like_NAD/FAD-binding_dom

SIRT5 SIRT2

2.46e-03121172IPR029035
Domain-

LZTR1 KBTBD8 KLHL38

3.38e-034811732.120.10.80
DomainMyosin_N

MYH13 MYH7B

3.87e-03151172PF02736
DomainMyosin_N

MYH13 MYH7B

3.87e-03151172IPR004009
DomainNicotinic_acetylcholine_rcpt

CHRNA6 CHRNB3

4.41e-03161172IPR002394
DomainDisintegrin_CS

ADAM21 ADAM28

4.41e-03161172IPR018358
DomainLRR_6

NLRP9 TLR3 NLRP4

4.96e-03551173PF13516
DomainKelch-typ_b-propeller

LZTR1 KBTBD8 KLHL38

4.96e-03551173IPR015915
DomainA/G_cyclase_CS

ADCY2 ADCY7

4.98e-03171172IPR018297
DomainThioredoxin_CS

NME8 TXN

4.98e-03171172IPR017937
DomainChannel_four-helix_dom

KCNA1 KCNA2 KCNC3

5.48e-03571173IPR027359
Domain-

KCNA1 KCNA2 KCNC3

5.48e-035711731.20.120.350
DomainMyosin_tail_1

MYH13 MYH7B

5.58e-03181172PF01576
DomainMyosin_tail

MYH13 MYH7B

5.58e-03181172IPR002928
DomainADAM_CR

ADAM21 ADAM28

5.58e-03181172PF08516
Domain-

ADCY2 ADCY7

5.58e-031811723.30.70.1230
DomainNucleotide_cyclase

ADCY2 ADCY7

5.58e-03181172IPR029787
DomainKelch

LZTR1 KBTBD8 KLHL38

5.75e-03581173SM00612
DomainWD40

EML6 DNAI3 WDR47 EML5 DNAI2 WDR82

5.83e-032591176PF00400
DomainGuanylate_cyc

ADCY2 ADCY7

6.21e-03191172PF00211
DomainGUANYLATE_CYCLASE_2

ADCY2 ADCY7

6.21e-03191172PS50125
DomainA/G_cyclase

ADCY2 ADCY7

6.21e-03191172IPR001054
DomainMyosin-like_IQ_dom

MYH13 MYH7B

6.21e-03191172IPR027401
Domain-

MYH13 MYH7B

6.21e-031911724.10.270.10
DomainGUANYLATE_CYCLASE_1

ADCY2 ADCY7

6.21e-03191172PS00452
DomainCYCc

ADCY2 ADCY7

6.21e-03191172SM00044
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9C LGALS9B LGALS9

4.21e-083122319776007
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B LGALS9

4.21e-083122333316546
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9C LGALS9B LGALS9

4.21e-08312239038233
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B LGALS9

4.21e-083122328704475
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B LGALS9

4.21e-083122323836896
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B LGALS9

4.21e-08312237890611
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9C LGALS9B LGALS9

4.21e-083122322341088
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B LGALS9

4.21e-083122332380082
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B LGALS9

4.21e-083122323667648
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B LGALS9

4.21e-083122328877989
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B LGALS9

4.21e-083122319800850
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9C LGALS9B LGALS9

4.21e-083122338987795
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B LGALS9

4.21e-083122337105392
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B LGALS9

4.21e-083122336479526
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B LGALS9

4.21e-083122323242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B LGALS9

4.21e-083122319851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B LGALS9

4.21e-083122333923930
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B LGALS9

4.21e-083122331969388
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9C LGALS9B LGALS9

4.21e-083122335241678
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9C LGALS9B LGALS9

4.21e-083122322627368
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9C LGALS9B LGALS9

4.21e-083122333153471
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9C LGALS9B LGALS9

4.21e-083122322052881
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9C LGALS9B LGALS9

4.21e-083122335643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9C LGALS9B LGALS9

4.21e-083122323408620
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9C LGALS9B LGALS9

4.21e-083122329458010
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9C LGALS9B LGALS9

4.21e-083122326582205
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9C LGALS9B LGALS9

4.21e-08312239153289
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9C LGALS9B LGALS9

4.21e-083122318974023
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9C LGALS9B LGALS9

4.21e-083122323144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9C LGALS9B LGALS9

4.21e-083122329651447
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9C LGALS9B LGALS9

4.21e-083122321146220
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9C LGALS9B LGALS9

4.21e-083122328990062
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9C LGALS9B LGALS9

4.21e-083122318579572
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9C LGALS9B LGALS9

4.21e-083122316990264
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9C LGALS9B LGALS9

4.21e-083122318005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9C LGALS9B LGALS9

4.21e-083122323585851
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9C LGALS9B LGALS9

4.21e-083122324477688
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9C LGALS9B LGALS9

4.21e-083122329433546
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9C LGALS9B LGALS9

4.21e-083122325898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9C LGALS9B LGALS9

4.21e-083122331937306
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9C LGALS9B LGALS9

4.21e-083122321426359
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9C LGALS9B LGALS9

4.21e-083122318282810
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9C LGALS9B LGALS9

4.21e-083122324083426
Pubmed

Galectin-9 in synergy with NF-ÎşB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9C LGALS9B LGALS9

4.21e-083122337279535
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9C LGALS9B LGALS9

4.21e-083122325931247
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9C LGALS9B LGALS9

4.21e-083122317560833
Pubmed

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.

LGALS9C LGALS9B LGALS9 TLR3

6.98e-0812122423817958
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9C LGALS9B LGALS9

1.68e-074122338686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9C LGALS9B LGALS9

1.68e-074122322677125
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9C LGALS9B LGALS9

1.68e-074122319234217
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9C LGALS9B LGALS9

1.68e-074122335715604
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9C LGALS9B LGALS9

1.68e-074122319017954
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9C LGALS9B LGALS9

1.68e-074122336459823
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9C LGALS9B LGALS9

1.68e-074122329611821
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9C LGALS9B LGALS9

1.68e-074122333727589
Pubmed

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.

LGALS9C LGALS9B LGALS9

1.68e-074122325578313
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9C LGALS9B LGALS9

1.68e-074122318826117
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9C LGALS9B LGALS9

1.68e-074122338853593
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9C LGALS9B LGALS9

1.68e-074122321575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9C LGALS9B LGALS9

1.68e-074122318346632
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9C LGALS9B LGALS9

1.68e-074122319670381
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9C LGALS9B LGALS9

1.68e-074122325450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9C LGALS9B LGALS9

1.68e-074122316286920
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9C LGALS9B LGALS9

1.68e-074122334369876
Pubmed

Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.

LGALS9C LGALS9B LGALS9

1.68e-074122333203936
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9C LGALS9B LGALS9

1.68e-074122333963043
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9C LGALS9B LGALS9

1.68e-074122333107565
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9C LGALS9B LGALS9

1.68e-074122330763585
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9C LGALS9B LGALS9

1.68e-074122319362679
Pubmed

Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.

LGALS9C LGALS9B LGALS9

1.68e-074122329844236
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9C LGALS9B LGALS9

1.68e-074122320463811
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9C LGALS9B LGALS9

1.68e-074122332855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9C LGALS9B LGALS9

1.68e-074122323657851
Pubmed

The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.

LGALS9C LGALS9B LGALS9

1.68e-074122324333756
Pubmed

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

LGALS9C LGALS9B LGALS9

1.68e-074122324958847
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS9C LGALS9B LGALS9

1.68e-074122330120235
Pubmed

Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.

LGALS9C LGALS9B LGALS9

1.68e-074122311839756
Pubmed

Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.

LGALS9C LGALS9B LGALS9

1.68e-074122322021615
Pubmed

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.

LGALS9C LGALS9B LGALS9

4.19e-075122328951537
Pubmed

Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner.

LGALS9C LGALS9B LGALS9

4.19e-075122334847625
Pubmed

Astrocyte galectin-9 potentiates microglial TNF secretion.

LGALS9C LGALS9B LGALS9

4.19e-075122325158758
Pubmed

Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy.

LGALS9C LGALS9B LGALS9

4.19e-075122326278059
Pubmed

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.

LGALS9C LGALS9B LGALS9

4.19e-075122321385853
Pubmed

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.

LGALS9C LGALS9B LGALS9

4.19e-075122329242193
Pubmed

Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice.

LGALS9C LGALS9B LGALS9

4.19e-075122322469568
Pubmed

C/EBPzeta (CHOP/Gadd153) is a negative regulator of LPS-induced IL-6 expression in B cells.

LGALS9C LGALS9B LGALS9

4.19e-075122319782405
Pubmed

Embryonic implantation in galectin 1/galectin 3 double mutant mice.

LGALS9C LGALS9B LGALS9

4.19e-07512239566950
Pubmed

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

LGALS9C LGALS9B LGALS9

4.19e-075122337352334
Pubmed

Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model.

LGALS9C LGALS9B LGALS9

4.19e-075122333664349
Pubmed

The glucose transporter 2 regulates CD8+ T cell function via environment sensing.

LGALS9C LGALS9B LGALS9

4.19e-075122337884694
Pubmed

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.

LGALS9C LGALS9B LGALS9

8.36e-076122328394331
Pubmed

Tim3 binding to galectin-9 stimulates antimicrobial immunity.

LGALS9C LGALS9B LGALS9

8.36e-076122320937702
Pubmed

Galectins in mouse embryogenesis.

LGALS9C LGALS9B LGALS9

8.36e-07612238674632
Pubmed

Tim-3/galectin-9 regulate the homeostasis of hepatic NKT cells in a murine model of nonalcoholic fatty liver disease.

LGALS9C LGALS9B LGALS9

8.36e-076122323296703
Pubmed

Role of galectin-1 in the developing mouse olfactory system.

LGALS9C LGALS9B LGALS9

1.46e-06712238873770
Pubmed

Mammalian galectins bind galactoseβ1-4fucose disaccharide, a unique structural component of protostomial N-type glycoproteins.

LGALS9C LGALS9B LGALS9

2.33e-068122323751344
Pubmed

Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer.

LGALS9C LGALS9B LGALS9

2.33e-068122331661141
Pubmed

Mesenchymal stem cells protect against sepsis-associated acute kidney injury by inducing Gal-9/Tim-3 to remodel immune homeostasis.

LGALS9C LGALS9B LGALS9

2.33e-068122336883358
Pubmed

Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.

KCNA1 KCNA2 KCNC3

3.48e-06912239488722
Pubmed

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry.

LGALS9C LGALS9B LGALS9

3.48e-069122321670307
Cytoband12p13.2

TAS2R31 TAS2R43 TAS2R46

2.39e-0445122312p13.2
GeneFamilyGalectins

LGALS9C LGALS9B LGALS9

5.92e-0515943629
GeneFamilyBasic leucine zipper proteins|BTB domain containing

LZTR1 KBTBD8 MYNN KLHL38 BTBD16 ZBTB39

7.07e-05134946861
GeneFamilySirtuins

SIRT5 SIRT2

5.52e-047942938
GeneFamilyTaste 2 receptors

TAS2R31 TAS2R43 TAS2R46

1.09e-03399431162
GeneFamilyPotassium voltage-gated channels

KCNA1 KCNA2 KCNC3

1.17e-0340943274
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY2 ADCY7

1.17e-031094253
GeneFamilyWD repeat domain containing

EML6 DNAI3 WDR47 EML5 DNAI2 WDR82

2.46e-03262946362
GeneFamilyMyosin heavy chains

MYH13 MYH7B

2.69e-03159421098
GeneFamilyCholinergic receptors nicotinic subunits

CHRNA6 CHRNB3

3.06e-0316942173
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM2 PRDM15

3.46e-03179421197
GeneFamilyNLR family

NLRP9 NLRP4

7.42e-0325942666
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP9 NLRP4

7.42e-0325942994
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM21 ADAM28

8.63e-032794247
GeneFamilyETS transcription factor family

ETV1 ETV5

9.26e-0328942534
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 ETV5 ITGA9 CELSR1 EML5 FAM13A CADPS2

7.27e-071841217ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

LRRK2 ETV1 ETV5 BTBD16 CFAP221 CADPS2 AGBL1

9.67e-07192121706013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CHRNA6 FPR1 KBTBD8 GPR84 ETV5 ADAM28 PLEK

1.27e-062001217f0e7c2f07a7065511bf0b6521ce2e74e04e48544
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

HTR2B GPR84 ETV5 ITGA9 ADCY2 ADAM28

6.91e-061691216241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 TXNDC11 CELSR1 FARP1 CADPS2 AGBL1

9.59e-061791216815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

9.90e-061801216198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 RTKN2 CELSR1 FADS3 FARP1 CADPS2

1.12e-05184121642ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 ETV1 ETV5 ITGA9 CELSR1 CADPS2

1.16e-0518512160d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 RTKN2 CELSR1 EML5 FAM13A CADPS2

1.19e-0518612164e94158db52df41d71e67b02b9895a358eebee0f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

1.19e-051861216acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 ETV5 ITGA9 CELSR1 FAM13A CADPS2

1.19e-051861216e83718fabb057100835d3357df407f283d23fe16
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

LRRK2 ITGA9 CELSR1 FARP1 CADPS2 AGBL1

1.23e-05187121681cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 ETV1 ETV5 CELSR1 FAM13A CADPS2

1.27e-0518812164bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ATAD5 NCAPH RTKN2 BRCA2 TK1 FOXF1

1.35e-051901216e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

1.39e-051911216a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

LRRK2 CELSR1 FARP1 CFAP221 CADPS2 AGBL1

1.43e-051921216499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

1.43e-05192121658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

LRRK2 CELSR1 FARP1 CFAP221 CADPS2 AGBL1

1.43e-051921216efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HTR2B FPR1 GPR84 ADAM28 LGALS9 NLRP4

1.43e-0519212164037b4c4fbb40541b8c424c36d3871a57891b8dd
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

1.43e-051921216fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

1.47e-051931216738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell390C-Myeloid-Dendritic-cDC2|390C / Donor, Lineage, Cell class and subclass (all cells)

FPR1 OTUD1 GPR84 KMO LGALS9 PLEK

1.51e-051941216705fa653c11b6c8a427e007533aa4a4bb5845078
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 ETV1 ETV5 BTBD16 CADPS2 AGBL1

1.51e-05194121697534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell343B-Myeloid-Dendritic|343B / Donor, Lineage, Cell class and subclass (all cells)

OTUD1 KBTBD8 GPR84 NCAPH ADAM28 TK1

1.61e-051961216fdb4f7e757b30b974ed3cd80c47beb4557a70845
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LGALS9C FPR1 ADAM28 ADCY7 LGALS9 PLEK

1.61e-051961216e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA9 RTKN2 CELSR1 FADS3 EML5 CADPS2

1.65e-051971216b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FPR1 KBTBD8 GPR84 ADAM28 NME8 PLEK

1.65e-05197121661bda9b5102fdbce902bb976d1aa62f2c799d2fb
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRRK2 ETV5 CELSR1 EML5 FAM13A CADPS2

1.65e-0519712161485933986921ff45669d9b7501c8d17050b3e97
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

LRRK2 ETV1 ETV5 NOP14 FAM13A CADPS2

1.65e-0519712161a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

LRRK2 ETV1 ETV5 GSTM3 FAM13A CADPS2

1.70e-051981216d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRRK2 ETV1 ETV5 CELSR1 FAM13A CADPS2

1.70e-051981216285f729140b1df029c24f6ca1d2438470ac51794
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

1.70e-051981216f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LGALS9C OTUD1 ADAM28 ADCY7 LGALS9 PLEK

1.70e-051981216cc808d872d2404a79ec119bb0be62688a30c93a7
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRRK2 ETV1 ETV5 CFAP221 CADPS2 AGBL1

1.70e-0519812162e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRRK2 ETV1 ETV5 GSTM3 FAM13A CADPS2

1.70e-051981216aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FPR1 OTUD1 ADAM28 ADCY7 LGALS9 PLEK

1.75e-051991216e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KBTBD8 GPR84 KMO GSTM3 PLEK

4.78e-051451215778655fffd73df101e656154a41b478a1b695116
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 RASGRP1 NLRP9 TK1 CADPS2

6.36e-051541215cd99428c282d566b5dbd31fd5a0371b7ffe9ffa2
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGEL2 KBTBD8 ITGA9 PKDREJ FAM13A

7.18e-051581215f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGEL2 KBTBD8 ITGA9 PKDREJ FAM13A

7.18e-0515812158c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 FPR1 ETV5 ADCY7 KCNA2

8.31e-0516312158dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 FPR1 ETV5 ADCY7 KCNA2

8.31e-051631215fd243ca223079033be480a24817a399f281fa4d4
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDD1 EML6 TXNDC11 KCNRG PRDM15

8.81e-0516512156e8370b8e747d8ef44a2413a993291a3cd83a77c
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

FAM120B RTKN2 SIRT2 FAM118A EIF2A

9.32e-051671215cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 NCAPH RTKN2 BRCA2 TK1

9.86e-051691215e7514956b2e4298222ec443f98b2f5289451786e
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RHBDD1 EML6 TXNDC11 CELSR1 BRCA2

1.01e-041701215c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DPY19L2 LGALS9B ITGA9 NCAPH TK1

1.04e-041711215b113fbebb89056af0b9c775d2fb6552206a80467
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

ATAD5 NCAPH RASGRP1 BRCA2 TK1

1.04e-0417112154ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HTR2B FPR1 OTUD1 PLEK MAST3

1.07e-04172121553dbfe1ac658fd94370cf8e745048cb67fda1daf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS9C LGALS9B NCAPH NME8 TK1

1.07e-041721215fe3d0d8cb5f613ac2cfff450599698f1533a354f
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL9 ATAD5 NCAPH TK1 TLR3

1.10e-04173121515af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCellEpithelial-Epithelial-C_(AT2)|Epithelial / shred on cell class and cell subclass (v4)

LRRK2 ETV5 ITGA9 ADCY7 KCNC3

1.10e-041731215f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FPR1 KBTBD8 GPR84 KMO PLEK

1.19e-04176121598176bf3c961d5262593e2d5d002836adb010e13
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|356C / Donor, Lineage, Cell class and subclass (all cells)

DPY19L2 ITGA9 NCAPH BRCA2 TK1

1.19e-0417612154bba41ebf9dd187c8705a6997ed039878de62b4e
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 ETV1 ITGA9 SVEP1 FAM13A

1.22e-041771215b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KBTBD8 GPR84 KCNC3 PLEK ZNF439

1.22e-041771215f28243b51be104cb3adcde63f03fc2206ed3121e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS9B ATAD5 NCAPH BRCA2 TK1

1.26e-041781215dbde3305e0c6a81593fe614e3f2e746b32cc16a7
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

CYP2A7 ITGA9 ADAM28 CELSR1 FARP1

1.26e-04178121535a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

LGALS9C LGALS9B ADCY2 ADAM28 CELSR1

1.29e-0417912151fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 NCAPH RTKN2 BRCA2 TK1

1.32e-041801215401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 SVEP1 LGALS9 AGBL1 FOXF1

1.32e-04180121512537d8a569faa69f474284d2c201475722b8ca1
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 RTKN2 CELSR1 FADS3 FARP1

1.36e-041811215b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FPR1 GPR84 ADCY7 KCNC3 PLEK

1.36e-041811215bad77767e64cc093a827a6b0f3f401f3f108e457
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CYP2A7 LRRK2 ITGA9 FAM13A CADPS2

1.36e-041811215c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 KMO BTBD16 CFAP221 SERINC5

1.39e-041821215eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCelldroplet-Lung-LUNG-1m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 ETV5 ITGA9 CELSR1 KCNC3

1.39e-041821215c1e0be27064e14043b78ae501b02d4e9542267a3
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 ETV5 ITGA9 CELSR1 KCNC3

1.39e-0418212153c9b4869d357884ae4bcd22a9872faf83a5cfc6d
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KBTBD8 KCNA1 KCNA2 DNAI2 SERINC5

1.43e-041831215876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KBTBD8 KCNA1 KCNA2 DNAI2 SERINC5

1.43e-041831215b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCellCTRL-Myeloid-cDC|CTRL / Disease state, Lineage and Cell class

DNAI3 ADAM28 TLR3 DNAI2 FAM118A

1.43e-04183121520c4d16de7e090df3556a4458f783383a26871b6
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ATAD5 ETV1 NCAPH BRCA2 TK1

1.43e-041831215a716b446c2bf5aa294b8f580aa845098fae76354
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 ETV1 ETV5 GSTM3 CADPS2

1.43e-041831215e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KBTBD8 KCNA1 KCNA2 DNAI2 SERINC5

1.43e-0418312158330c39184ce076e1f95fd3725b68af551d89db0
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 ETV5 ITGA9 CELSR1 KCNC3

1.47e-04184121524cbe9f2461ea920954e44bf3b2c2a6a5d4debfb
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 ETV5 ITGA9 CELSR1 KCNC3

1.47e-04184121598079fd048a63b51bbdf3833b6f15bf0ae99ea90
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LRRK2 ETV1 CFAP221 CADPS2 AGBL1

1.47e-041841215369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ETV1 ETV5 ITGA9 GSTM3 CELSR1

1.47e-04184121551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 LRRK2 CELSR1 CFAP221 SERINC5

1.47e-041841215da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ITGA9 FARP1 CFAP221 CADPS2 AGBL1

1.47e-041841215102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 ETV5 ITGA9 CELSR1 KCNC3

1.47e-04184121586c1551c4f7c7d0c35c14852b01b1e602fa5092a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATAD5 EML6 NCAPH RTKN2 TK1

1.51e-04185121547c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ITGA9 FARP1 CFAP221 CADPS2 AGBL1

1.51e-041851215673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 ITGA9 FARP1 CADPS2 AGBL1

1.51e-04185121598b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

ETV1 NCAPH BRCA2 TK1 TAS2R46

1.51e-0418512150ae9c646679c69a553eda670aef0e0495feb0286
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ETV1 ETV5 ITGA9 GSTM3 CELSR1

1.51e-0418512158ca1374501eca01d8468130b74d50abfd4329fbe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 NCAPH RTKN2 BRCA2 TK1

1.51e-04185121530e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellproximal-3-Hematologic-Myeloid_Dendritic_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OTUD1 KBTBD8 TLR3 PLEK FAM118A

1.54e-041861215c920dffd24f051b54d8b48f801fffc928d99e135
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OTUD1 KBTBD8 TLR3 PLEK FAM118A

1.54e-041861215d740aca5dc4240851ba7bc5988c0970d785ad0c2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 CELSR1 CFAP221 CADPS2 AGBL1

1.54e-0418612152ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FPR1 GPR84 NME8 LGALS9 PLEK

1.54e-041861215cb4ea1bc1427230070e9696baeda7de241c354b1
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OTUD1 KBTBD8 TLR3 PLEK FAM118A

1.54e-0418612154ca7f6c043874a0c536f75af5ca24c7c66725e54
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 NCAPH SVEP1 BRCA2 TK1

1.58e-041871215e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCelllymphoid-B_cell-Naive_B_cell|World / Lineage, cell class and subclass

ADAM28 KMO PRDM2 LGALS9 FADS3

1.58e-041871215904ffd8cf4513e86fcd4c2b7faf24a34fbd2dce3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 NCAPH SVEP1 BRCA2 TK1

1.58e-041871215cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 RTKN2 CELSR1 FARP1 CADPS2

1.58e-04187121558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 EML6 RASGRP1 CFAP221 CADPS2

1.58e-041871215f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 NCAPH RTKN2 BRCA2 TK1

1.58e-0418712159351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCelllymphoid-B_cell|World / Lineage, cell class and subclass

ADAM28 KMO PRDM2 LGALS9 FADS3

1.58e-0418712152abbc01fd7f5b4e52113699625287893c991f8da
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

RTKN2 RASGRP1 FAM13A SERINC5 FAM118A

1.62e-041881215b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FPR1 ETV5 ADAM28 ADCY7 PLEK

1.62e-0418812150d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
DiseaseLung Diseases, Obstructive

NR3C1 FOXF1

4.35e-0531132C0600260
Diseasebipolar disorder (implicated_via_orthology)

ETV1 ETV5

3.01e-0471132DOID:3312 (implicated_via_orthology)
Diseasegeneralized anxiety disorder (implicated_via_orthology)

HTR2B NR3C1

4.01e-0481132DOID:14320 (implicated_via_orthology)
Diseaselung non-small cell carcinoma (is_marker_for)

NR3C1 ITGA9 NCAPH ADAM28 TK1

4.95e-041691135DOID:3908 (is_marker_for)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:0110454 (implicated_via_orthology)
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:0111269 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:0080719 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:3429 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease, chronic bronchitis

FAM13A CFAP221

6.41e-04101132EFO_0000341, EFO_0006505
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH13 MYH7B

6.41e-04101132DOID:0111596 (implicated_via_orthology)
Diseasecocaine use

CHRNA6 CHRNB3

7.82e-04111132C3496069
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

EML6 ASB3 DNAI2

8.34e-04481133EFO_0009268, MONDO_0001627, MONDO_0004975
DiseaseMalignant neoplasm of breast

KBTBD8 KIF16B ITGA9 PKDREJ NME8 TXN LHCGR NLRP9 BRCA2 FARP1 UQCC1 DHX32

8.59e-04107411312C0006142
Diseasedistal myopathy (implicated_via_orthology)

MYH13 MYH7B

9.36e-04121132DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH13 MYH7B

9.36e-04121132DOID:2106 (implicated_via_orthology)
DiseaseTOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)

CHRNA6 CHRNB3

9.36e-04121132C1861063
Diseasedepressive disorder (biomarker_via_orthology)

NR3C1 KMO CHRNB3

1.05e-03521133DOID:1596 (biomarker_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH13 MYH7B

1.10e-03131132DOID:397 (implicated_via_orthology)
Diseaseinterleukin 12 measurement

GRID2 CAPN11 KCNC3

1.11e-03531133EFO_0004753
DiseaseHamman-Rich syndrome

FAM13A PARN

1.28e-03141132C0085786
Diseasesulfate measurement

DNAI3 CADPS2

1.28e-03141132EFO_0007864
Diseaseautoimmune thyroid disease

ADCY7 RTKN2 RASGRP1 TLR3

1.43e-031261134EFO_0006812
Diseaseobesity (implicated_via_orthology)

ETV1 ETV5 NR3C1 CAPN11 GSTM3

1.45e-032151135DOID:9970 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH13 MYH7B

1.48e-03151132DOID:0050646 (implicated_via_orthology)
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNA6 CHRNB3

1.68e-03161132DOID:3635 (implicated_via_orthology)
Diseaseobsolete_red blood cell distribution width

TTLL9 UBE3B KBTBD8 TXNDC11 CHRNB3 CAPN11 TK1 ASB3 DHX32 PLEK POLK TUBD1 MAST3

1.96e-03134711313EFO_0005192
DiseaseStuttering

KIF16B MS4A2 ASB3 AGBL1

2.26e-031431134HP_0025268
DiseaseUsual Interstitial Pneumonia

FAM13A PARN

2.38e-03191132C4721509
DiseaseHamman-Rich Disease

FAM13A PARN

2.38e-03191132C4721508
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

FADS3 PARN

2.38e-03191132OBA_2045199
DiseaseBipolar Disorder

CHRNA6 NR3C1 ITGA9 ADCY2 CHRNB3 RASGRP1 BRCA2

2.45e-034771137C0005586
DiseaseProstatic Neoplasms

ETV1 ETV5 NR3C1 ADAM28 GSTM3 BRCA2 INTS4 POLK

2.59e-036161138C0033578
DiseaseMalignant neoplasm of prostate

ETV1 ETV5 NR3C1 ADAM28 GSTM3 BRCA2 INTS4 POLK

2.59e-036161138C0376358
DiseaseFamilial Idiopathic Pulmonary Fibrosis

FAM13A PARN

2.64e-03201132C4721952
DiseaseIdiopathic Pulmonary Fibrosis

FAM13A PARN

2.91e-03211132C1800706
Diseaseasthma (is_implicated_in)

NR3C1 GSTM3 MS4A2 TLR3

3.17e-031571134DOID:2841 (is_implicated_in)
Diseasehypertrophic cardiomyopathy (is_implicated_in)

LZTR1 MYH7B

3.19e-03221132DOID:11984 (is_implicated_in)
DiseaseBronchiectasis

NME8 DNAI2

3.19e-03221132C0006267
DiseaseQRS duration, response to sulfonylurea

ZNF638 UQCC1

3.49e-03231132EFO_0005055, EFO_0007922
DiseaseDepression, Bipolar

NR3C1 ADCY2 KMO

3.50e-03791133C0005587
Diseasenon-melanoma skin carcinoma

MYH7B GRID2 BRCA2 FARP1 UQCC1

3.59e-032651135EFO_0009260
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH13 MYH7B YME1L1

3.63e-03801133DOID:12930 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KDCTTPLEMFSNVEF

ATAD5

96

Q96QE3
TSDPTFSLMFDGCFE

ATAD5

1336

Q96QE3
FSLMFDGCFEEIKFS

ATAD5

1341

Q96QE3
KFFETKCFMASFSTE

MS4A2

166

Q01362
DVTFFPFDRQNCSMK

CHRNB3

156

Q05901
TCVLTKERFGDFMLF

HTR2B

206

P41595
ETVMTFFKSFPENCC

BTBD16

296

Q32M84
CVMDKALSFYIPTDF

ADAM28

361

Q9UKQ2
PAEKFTNCSYADFMK

ADAM21

371

Q9UKJ8
EKIAASFPFSFCVMD

RASGRP1

496

O95267
SFPFSFCVMDKDREG

RASGRP1

501

O95267
GFPDCSIEAAMVKVF

ACAD9

371

Q9H845
MKCVSVLRFDSSAPF

CELSR1

1316

Q9NYQ6
DCVCVMFASVPDFKV

ADCY7

876

P51828
MFASVPDFKVFYTEC

ADCY7

881

P51828
DFDSFISCFLRLKTM

CAPN11

696

Q9UMQ6
FCLYTEEFASKDMTP

DHX32

401

Q7L7V1
DFMFEQCDPTLSLKV

DNAI2

436

Q9GZS0
QLMLESPDDIFCFKF

DNAI3

391

Q8IWG1
CTSVSPLQFDFKVMF

CC2D2B

516

Q6DHV5
DKLAPAFTMSSCSFL

AGBL1

946

Q96MI9
FTQAKFDSEMPCETV

KIF16B

231

Q96L93
KFLEVMGFSCAAFTL

OR6C1

191

Q96RD1
PSFAEKCLDFLVDMF

INTS4

406

Q96HW7
ADLSEFKEMTTCVFP

PARN

306

O95453
MAPTCVFLASKVEEF

CCNC

86

P24863
VFSGSDTDPDMAFCK

PLOD3

481

O60568
KMPAFSSCFEVVSGA

OTUD1

71

Q5VV17
SFLDACFSSVITPKM

OR4C15

66

Q8NGM1
FFACPSKAGFFTNIM

KCNA2

241

P16389
FACPSKTDFFKNIMN

KCNA1

241

Q09470
CMAPISFFAISAAFK

LHCGR

581

P22888
FPVAVCRDKMFVFSG

LZTR1

231

Q8N653
PDIFSKASECMQVIF

MAGEA8

151

P43361
SKDRMIFAATFCAPK

MAGEL2

746

Q9UJ55
GMPFDLCFLVQSSDF

LGALS9C

96

Q6DKI2
AGMTDFPKIFCETSQ

METTL25

86

Q8N6Q8
GMPFDLCFLVQSSDF

LGALS9B

96

Q3B8N2
GMPFDLCFLVQSSDF

LGALS9

96

O00182
RAEKTVDMFACLAPF

GRID2

551

O43424
EECMFPKASDASFRA

MYH7B

581

A7E2Y1
NTSCDFLPAMKSAEF

LDAF1

141

Q96B96
ICQASFATPKMIADF

OR4K5

71

Q8NGD3
VCVASFATPKMIADF

OR4K15

71

Q8NH41
VYKFVCDPEALFSMA

ETV1

411

P50549
SLFQAMVDFTFFKPD

NRDE2

491

Q9H7Z3
CKIKMEDFAFIANPS

MYNN

111

Q9NPC7
ACPKVESFSARMNFL

LRRK2

1151

Q5S007
CFQTFLDKTMSIEFP

NR3C1

736

P04150
EFPNLKAFMCRFEAL

GSTM3

181

P21266
KFVCDPDALFSMAFP

ETV5

446

P41161
FEMAKVLCKFSLFTA

GMPR2

61

Q9P2T1
AFFRVFGSCSKTIEM

KCNRG

121

Q8N5I3
FCCFFKDPKRAMEAF

NLRP4

311

Q96MN2
TCAPEFDFMEKATPL

DPY19L2

476

Q6NUT2
CQMFPESASDAIKFV

NOP14

506

P78316
PDFMVTLKTDFSARC

FAM13A

896

O94988
FFPDIVEFCEAMANA

TK1

101

P04183
SSEFGKVTRMCFAVF

GPR84

311

Q9NQS5
FAKCIRFPLMEDTFI

KBTBD8

236

Q8NFY9
SDFLKCSVGFPFMRS

ITGA9

701

Q13797
MFTFLFGEFESPACE

EBLN1

206

P0CF75
KPSFFQDCLMEVFDD

FAM118A

106

Q9NWS6
PAIFKSSCPMDITFF

CHRNA6

151

Q15825
CIQKADIFMFDEPSS

ABCE1

231

P61221
VCVMFASIPDFKEFY

ADCY2

886

Q08462
FSSPVCMAFQKDCEF

ASB3

316

Q9Y575
KSFTCTLFMPFEEFE

KMO

231

O15229
LAAMECAFPKEFANR

BRCA2

2631

P51587
GADFCYAIEVFKPMA

PRMT7

86

Q9NVM4
TLEFLMASRDFCKSF

FARP1

291

Q9Y4F1
DSIMKFSECYGPVFT

CYP2A7

56

P20853
CMFFNAVKEGDTVIF

CADPS2

556

Q86UW7
FAENPFVVSMFCSFD

MAST2

566

Q6P0Q8
FAENPFVVSMFCSFE

MAST3

421

O60307
TGDDFGMVKLFDFPC

EML5

1906

Q05BV3
CKDIPSFVIQMDFSA

EML6

1811

Q6ZMW3
TEFCAVYGFMPAKAT

EIF2A

286

Q9BY44
AAEDMKLFDASPTFF

FADS3

121

Q9Y5Q0
DTLKYTCSPEFDFME

DPY19L2P2

281

Q6ZN68
TCSPEFDFMEKATLL

DPY19L2P2

286

Q6ZN68
TDFEFKLEALMCTNP

FAM120B

536

Q96EK7
ETFMFPCQHCERKFT

PRDM2

356

Q13029
LSVFDMGFSSVTCPK

OR10D3

66

Q8NH80
KSCDSFNSFMLPIDV

CFAP221

741

Q4G0U5
PSMCDRKEFVFSFNA

FOXF1

336

Q12946
FCLFKMGANVFDTDV

RTKN2

131

Q8IZC4
SFGSLENKPVFMFCK

TAS2R31

251

P59538
SFGSLENKPVFMFCK

TAS2R43

251

P59537
SFESLENKPVFMFCE

TAS2R46

251

P59540
ENKPVFMFCEAIAFS

TAS2R46

256

P59540
YLCKSEEFMDPATFI

TEX47

216

Q8TBZ9
VAEFMDEPDFKRSCA

RHBDD1

126

Q8TEB9
SMDFCFPLDFVSNLF

TMEM191A

21

Q9H0A3
TDDKTFQCEMCFRFF

PRDM15

821

P57071
GPISTMFCDFTNDLF

PKDREJ

901

Q9NTG1
TSPCQDFGKRMFVFK

PLEK

56

P08567
DFCFTSTLPFFMVRK

FPR1

71

P21462
ARFFSCMQSDFLKVD

SIRT2

241

Q8IXJ6
FADVCFSSNVTPKML

OR5M9

66

Q8NGP3
AFETTLGKMVPSFCS

SVEP1

821

Q4LDE5
FLCSEMFFKPSLIKS

ACTL7A

316

Q9Y615
FESVLCAPDALFMVA

SLC25A13

81

Q9UJS0
CAPDALFMVAFQLFD

SLC25A13

86

Q9UJS0
IDPMFQKTAASFDEC

NCAPH

241

Q15003
KDRFTFVFFLNVCEM

NLRP9

176

Q7RTR0
ASECEVKCMPTFQFF

TXN

66

P10599
EVEKCDSFSGFFIIM

TUBD1

126

Q9UJT1
LPSSVFSCAFEQKML

WDR47

251

O94967
PMKTDIFDEFFSSSA

USPL1

1056

Q5W0Q7
CKDSAPFELFFMINT

TLR3

696

O15455
TENKFSFMTCPFILN

UBE3A

471

Q05086
TCLQFNPKFMTFASA

WDR82

286

Q6UXN9
EDAANVAKFMDAFFP

NME8

291

Q8N427
AMCSGAFFIPDQDTF

SERINC5

136

Q86VE9
CLDGPSISENFKMFS

POLK

646

Q9UBT6
LEEECMFPKATDTSF

MYH13

536

Q9UKX3
EKTDFEEFFLRCQMP

UQCC1

126

Q9NVA1
GIFLFSCDMCETKFF

ZBTB39

396

O15060
SVPQCSFFEMAAALD

TXNDC11

486

Q6PKC3
EAPSSECMFSDFLTK

YME1L1

51

Q96TA2
PDERAMFLKFVTSCS

UBE3B

966

Q7Z3V4
LEAAKCDFFPKTFEM

TTLL9

131

Q3SXZ7
VPKEMFTVGCCVFAF

SLC6A17

491

Q9H1V8
PSSSMADFRKFFAKA

SIRT5

36

Q9NXA8
KAAESMVKFYTCFPV

ZNF638

951

Q14966
TCEMFQDPVAFKDVA

ZNF439

11

Q8NDP4
FEFLMRITFCPDKVE

KCNC3

361

Q14003
ASMLQFPKLFEACSS

KLHL38

111

Q2WGJ6