Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N,N-dimethylaniline monooxygenase activity	FMO1 FMO2 FMO3 FMO4 FMO6P	4.49e-11	6	121	5	GO:0004499
GeneOntologyMolecularFunction	hypotaurine monooxygenase activity	FMO1 FMO2 FMO3 FMO4	6.38e-09	5	121	4	GO:0047822
GeneOntologyMolecularFunction	NADP binding	FMO1 NDOR1 FMO2 FMO3 FMO4 FDXR NOS1	9.40e-08	62	121	7	GO:0050661
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	FMO1 FMO2 FMO3 FMO4 FMO6P NOS1	1.42e-07	40	121	6	GO:0016709
GeneOntologyMolecularFunction	flavin adenine dinucleotide binding	FMO1 NDOR1 FMO2 FMO3 FMO4 XDH NOS1	1.67e-06	94	121	7	GO:0050660
GeneOntologyMolecularFunction	trimethylamine monooxygenase activity	FMO1 FMO3	3.64e-05	2	121	2	GO:0034899
GeneOntologyMolecularFunction	monooxygenase activity	FMO1 FMO2 FMO3 FMO4 FMO6P NOS1	7.18e-05	115	121	6	GO:0004497
GeneOntologyMolecularFunction	oxidoreductase activity, acting on iron-sulfur proteins as donors	NDOR1 FDXR	1.09e-04	3	121	2	GO:0016730
GeneOntologyMolecularFunction	oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	NDOR1 FDXR	1.09e-04	3	121	2	GO:0016731
GeneOntologyMolecularFunction	NADPH binding	NDOR1 FDXR NOS1	5.10e-04	26	121	3	GO:0070402
GeneOntologyBiologicalProcess	NADPH oxidation	FMO1 FMO2 FDXR	1.61e-05	9	121	3	GO:0070995
GeneOntologyBiologicalProcess	postsynaptic density organization	LILRB2 DBN1 CSMD2 NRXN3 CNTNAP2	2.29e-05	58	121	5	GO:0097106
GeneOntologyBiologicalProcess	postsynaptic specialization organization	LILRB2 DBN1 CSMD2 NRXN3 CNTNAP2	6.11e-05	71	121	5	GO:0099084
Domain	Flavin_mOase	FMO1 FMO2 FMO3 FMO4	8.62e-09	5	122	4	IPR000960
Domain	DiMe-aniline_mOase	FMO1 FMO2 FMO3 FMO4	8.62e-09	5	122	4	IPR012143
Domain	FMO-like	FMO1 FMO2 FMO3 FMO4	8.62e-09	5	122	4	PF00743
Domain	Flavin_mOase-like	FMO1 FMO2 FMO3 FMO4	8.62e-09	5	122	4	IPR020946
Domain	-	FMO1 FMO2 FMO3 FMO4 FDXR	3.21e-05	56	122	5	3.50.50.60
Domain	FAD/NAD-binding_dom	FMO1 FMO2 FMO3 FMO4 FDXR	3.50e-05	57	122	5	IPR023753
Domain	EGF_1	STAB2 NRG4 ADAM29 ITGB4 TENM2 VWDE NRXN3 TNN CNTNAP2	4.56e-05	255	122	9	PS00022
Domain	EGF-like_CS	STAB2 NRG4 ADAM29 ITGB4 TENM2 VWDE NRXN3 TNN CNTNAP2	5.46e-05	261	122	9	IPR013032
Domain	EGF_2	STAB2 NRG4 ADAM29 ITGB4 TENM2 VWDE NRXN3 TNN CNTNAP2	6.14e-05	265	122	9	PS01186
Domain	Cnn_1N	PDE4DIP CDK5RAP2	1.26e-04	3	122	2	IPR012943
Domain	Cnn_1N	PDE4DIP CDK5RAP2	1.26e-04	3	122	2	PF07989
Domain	EGF_3	STAB2 NRG4 ADAM29 TENM2 VWDE NRXN3 TNN CNTNAP2	1.57e-04	235	122	8	PS50026
Domain	EGF-like_dom	STAB2 NRG4 ADAM29 TENM2 VWDE NRXN3 TNN CNTNAP2	2.32e-04	249	122	8	IPR000742
Domain	FAD_binding_1	NDOR1 NOS1	6.24e-04	6	122	2	PF00667
Domain	-	NDOR1 NOS1	6.24e-04	6	122	2	1.20.990.10
Domain	FAD-binding_1	NDOR1 NOS1	6.24e-04	6	122	2	IPR003097
Domain	NADPH_Cyt_P450_Rdtase_dom3	NDOR1 NOS1	6.24e-04	6	122	2	IPR023173
Domain	EGF	STAB2 NRG4 TENM2 VWDE NRXN3 TNN CNTNAP2	8.98e-04	235	122	7	SM00181
Domain	Flavodoxin/NO_synth	NDOR1 NOS1	1.15e-03	8	122	2	IPR008254
Domain	Flavdoxin-like	NDOR1 NOS1	1.15e-03	8	122	2	IPR001094
Domain	FLAVODOXIN_LIKE	NDOR1 NOS1	1.15e-03	8	122	2	PS50902
Domain	Flavodoxin_1	NDOR1 NOS1	1.15e-03	8	122	2	PF00258
Domain	-	NDOR1 NOS1	1.84e-03	10	122	2	3.40.50.360
Domain	Flavoprotein-like_dom	NDOR1 NOS1	1.84e-03	10	122	2	IPR029039
Domain	Flavoprot_Pyr_Nucl_cyt_Rdtase	NDOR1 NOS1	1.84e-03	10	122	2	IPR001709
Domain	OxRdtase_FAD/NAD-bd	NDOR1 NOS1	2.68e-03	12	122	2	IPR001433
Domain	NAD_binding_1	NDOR1 NOS1	2.68e-03	12	122	2	PF00175
Domain	LamG	TSPEAR NRXN3 CNTNAP2	2.96e-03	44	122	3	SM00282
Domain	ConA-like_dom	TSPEAR ITGB4 MEFV RYR3 NRXN3 CNTNAP2	3.18e-03	219	122	6	IPR013320
Domain	ZP_2	CUZD1 DMBT1	3.66e-03	14	122	2	PS51034
Domain	-	PDZRN3 PDZRN4	3.66e-03	14	122	2	3.90.890.10
Domain	ZP_1	CUZD1 DMBT1	3.66e-03	14	122	2	PS00682
Domain	Neurexin-like	NRXN3 CNTNAP2	3.66e-03	14	122	2	IPR003585
Domain	4.1m	NRXN3 CNTNAP2	3.66e-03	14	122	2	SM00294
Domain	CUB	CSMD2 CUZD1 DMBT1	4.02e-03	49	122	3	PF00431
Domain	ZP	CUZD1 DMBT1	4.20e-03	15	122	2	SM00241
Domain	fn3	INSRR MYOM3 OBSCN ITGB4 TNN	4.24e-03	162	122	5	PF00041
Domain	CUB	CSMD2 CUZD1 DMBT1	4.26e-03	50	122	3	SM00042
Domain	-	CSMD2 CUZD1 DMBT1	4.76e-03	52	122	3	2.60.120.290
Domain	Sushi	SUSD4 CSMD2 CFB	4.76e-03	52	122	3	PF00084
Domain	VWF_type-D	VWDE MUC5AC	4.78e-03	16	122	2	IPR001846
Domain	VWFD	VWDE MUC5AC	4.78e-03	16	122	2	PS51233
Domain	SIAH-type	PDZRN3 PDZRN4	4.78e-03	16	122	2	IPR013323
Domain	VWD	VWDE MUC5AC	4.78e-03	16	122	2	SM00216
Domain	VWD	VWDE MUC5AC	4.78e-03	16	122	2	PF00094
Domain	CUB	CSMD2 CUZD1 DMBT1	5.02e-03	53	122	3	PS01180
Domain	CCP	SUSD4 CSMD2 CFB	5.29e-03	54	122	3	SM00032
Domain	ZP_dom	CUZD1 DMBT1	5.40e-03	17	122	2	IPR001507
Domain	Zona_pellucida	CUZD1 DMBT1	5.40e-03	17	122	2	PF00100
Domain	SUSHI	SUSD4 CSMD2 CFB	5.86e-03	56	122	3	PS50923
Domain	Sushi_SCR_CCP_dom	SUSD4 CSMD2 CFB	6.16e-03	57	122	3	IPR000436
Domain	CUB_dom	CSMD2 CUZD1 DMBT1	6.16e-03	57	122	3	IPR000859
Domain	Laminin_G	TSPEAR NRXN3 CNTNAP2	6.46e-03	58	122	3	IPR001791
Pathway	WP_CATALYTIC_CYCLE_OF_MAMMALIAN_FLAVINCONTAINING_MONOOXYGENASES_FMOS	FMO1 FMO2 FMO3 FMO4	6.73e-09	5	87	4	M39449
Pubmed	Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.	FMO1 FMO2 FMO3 FMO4 FMO6P	3.05e-12	6	123	5	12527699
Pubmed	The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression.	FMO1 FMO2 FMO3 FMO4	7.43e-10	5	123	4	8128486
Pubmed	Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine.	FMO1 FMO2 FMO3 FMO4	7.43e-10	5	123	4	32156684
Pubmed	A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.	FMO1 FMO2 FMO3 FMO4	7.43e-10	5	123	4	8311461
Pubmed	Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American.	FMO1 FMO3 FMO6P	4.32e-08	3	123	3	28413702
Pubmed	Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.	FMO1 FMO2 FMO3	4.32e-08	3	123	3	30381441
Pubmed	Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine.	FMO1 FMO2 FMO4	4.32e-08	3	123	3	19262426
Pubmed	The phenotype of a flavin-containing monooyxgenase knockout mouse implicates the drug-metabolizing enzyme FMO1 as a novel regulator of energy balance.	FMO1 FMO2 FMO4	4.32e-08	3	123	3	24792439
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	FMO1 FMO2 FMO3 FMO4 XDH FMO6P	1.32e-07	66	123	6	19898482
Pubmed	Quantitative analysis of FMO gene mRNA levels in human tissues.	FMO1 FMO2 FMO3	1.72e-07	4	123	3	16183778
Pubmed	The molecular biology of the flavin-containing monooxygenases of man.	FMO1 FMO2 FMO4	1.72e-07	4	123	3	7720101
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SESTD1 HK3 SPG7 TAGAP OBSCN ITGB4 LCMT2 KIFC2 C5orf34 PPP6C BAZ1A CDK5RAP2 MPHOSPH10 TSTD2 TNS1 RAB11FIP3	1.48e-06	1084	123	16	11544199
Pubmed	Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.	FMO1 FMO2 FMO3 FMO4	3.80e-06	30	123	4	20529763
Pubmed	The soluble nectin-4 ecto-domain promotes breast cancer induced angiogenesis via endothelial Integrin-β4.	ITGB4 NECTIN4	1.24e-05	2	123	2	30056265
Pubmed	Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate.	FMO1 FMO3	1.24e-05	2	123	2	34509493
Pubmed	Regulation of mouse liver flavin-containing monooxygenases 1 and 3 by sex steroids.	FMO1 FMO3	1.24e-05	2	123	2	9186481
Pubmed	Developmental and tissue-specific expression of human flavin-containing monooxygenases 1 and 3.	FMO1 FMO3	1.24e-05	2	123	2	16863467
Pubmed	Application of champedak mannose-binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma.	A2M CFB	1.24e-05	2	123	2	20575108
Pubmed	Influence of FMO1 and 3 polymorphisms on serum olanzapine and its N-oxide metabolite in psychiatric patients.	FMO1 FMO3	1.24e-05	2	123	2	23147717
Pubmed	Localization of genes encoding three distinct flavin-containing monooxygenases to human chromosome 1q.	FMO1 FMO3	1.24e-05	2	123	2	8486388
Pubmed	Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression.	FMO1 FMO3	1.24e-05	2	123	2	11809920
Pubmed	Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver.	FMO2 FMO3	1.24e-05	2	123	2	1542660
Pubmed	Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling.	XDH NOS1	1.24e-05	2	123	2	15486091
Pubmed	Drebrin E regulates neuroblast proliferation and chain migration in the adult brain.	DBN1 ICAM5	1.24e-05	2	123	2	28833685
Pubmed	Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.	IREB2 CDKAL1	1.24e-05	2	123	2	31941883
Pubmed	Drebrin Isoforms Critically Regulate NMDAR- and mGluR-Dependent LTD Induction.	DBN1 ICAM5	1.24e-05	2	123	2	30349460
Pubmed	Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family.	FMO2 FMO4	1.24e-05	2	123	2	1417778
Pubmed	The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development.	FMO1 FMO3	1.24e-05	2	123	2	15203093
Pubmed	Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.	FMO1 FMO2	1.24e-05	2	123	2	15144220
Pubmed	Functional activity of the mouse flavin-containing monooxygenase forms 1, 3, and 5.	FMO1 FMO3	3.71e-05	3	123	2	17721934
Pubmed	Identification and characterization of PDZRN3 and PDZRN4 genes in silico.	PDZRN3 PDZRN4	3.71e-05	3	123	2	15010864
Pubmed	Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival.	FANCF BRCA2	3.71e-05	3	123	2	14647419
Pubmed	Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.	FMO3 FMO4	3.71e-05	3	123	2	11551524
Pubmed	Gender differences in hepatic expression of flavin-containing monooxygenase isoforms (FMO1, FMO3, and FMO5) in mice.	FMO1 FMO3	3.71e-05	3	123	2	7473608
Pubmed	The Fanconi anemia/BRCA pathway is involved in DNA interstrand cross-link repair of adriamycin-resistant leukemia cells.	FANCF BRCA2	3.71e-05	3	123	2	24996439
Pubmed	Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny.	FMO1 FMO3	3.71e-05	3	123	2	26839369
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	A2M SESTD1 IREB2 ITGA7 PDE4DIP ZBTB5 CDK5RAP2 TNS1	4.73e-05	363	123	8	14691545
Pubmed	MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links.	NDOR1 BRCA2	7.41e-05	4	123	2	26338419
Pubmed	Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis.	XDH NOS1	7.41e-05	4	123	2	27609225
Pubmed	Polymorphisms in innate immunity genes and risk of childhood leukemia.	TICAM1 XDH MEFV CFB ICAM5 NOS1	9.59e-05	206	123	6	20438785
Pubmed	Risk of meningioma and common variation in genes related to innate immunity.	TICAM1 XDH MEFV CFB ICAM5 NOS1	9.85e-05	207	123	6	20406964
Pubmed	Common variation in genes related to innate immunity and risk of adult glioma.	TICAM1 XDH MEFV CFB ICAM5 NOS1	1.01e-04	208	123	6	19423540
Pubmed	Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.	SESTD1 PDE4DIP RAB11FIP3	1.19e-04	27	123	3	18685082
Pubmed	Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration.	NDOR1 BRCA2	1.23e-04	5	123	2	35404932
Pubmed	Cardiac nitric oxide synthase-1 localization within the cardiomyocyte is accompanied by the adaptor protein, CAPON.	XDH NOS1	1.23e-04	5	123	2	19800018
Pubmed	MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.	ITGB4 MUC5AC	1.23e-04	5	123	2	26751774
Pubmed	Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2.	FANCF BRCA2	1.23e-04	5	123	2	16621732
Pubmed	The opposing roles of laminin-binding integrins in cancer.	ITGA7 ITGB4	1.23e-04	5	123	2	27562932
Pubmed	Complement factor B is the downstream effector of TLRs and plays an important role in a mouse model of severe sepsis.	TICAM1 CFB	1.23e-04	5	123	2	24154627
Pubmed	HIC1 epigenetically represses CIITA transcription in B lymphocytes.	CIITA DNMT3A	1.23e-04	5	123	2	27720955
Pubmed	Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease.	A2M NOS1	1.23e-04	5	123	2	12782337
Pubmed	Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China.	ERCC6 BRCA2 POLQ	1.33e-04	28	123	3	19661089
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SESTD1 DMXL2 SRPK2 DBN1 SLC1A2 TENM2 PPP6C ICAM5 PDE4DIP CDK5RAP2 TNS1 NOS1	1.64e-04	963	123	12	28671696
Pubmed	FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3.	FANCF BRCA2	1.84e-04	6	123	2	18212739
Pubmed	Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes.	FMO1 FMO3	1.84e-04	6	123	2	20056567
Pubmed	Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo.	ITGA7 ITGB4	1.84e-04	6	123	2	11884516
Pubmed	Cell-Autonomous Regulation of Dendritic Spine Density by PirB.	NDOR1 LILRB2	1.84e-04	6	123	2	27752542
Pubmed	Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.	FANCF BRCA2	1.84e-04	6	123	2	20450923
Pubmed	Selected single-nucleotide polymorphisms in FOXE1, SERPINA5, FTO, EVPL, TICAM1 and SCARB1 are associated with papillary and follicular thyroid cancer risk: replication study in a German population.	TICAM1 EVPL	1.84e-04	6	123	2	27207655
Pubmed	Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia.	NDOR1 LILRB2	1.84e-04	6	123	2	25320232
Pubmed	The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling.	NDOR1 PDZRN3	2.58e-04	7	123	2	25198863
Pubmed	Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study.	ERCC6 BRCA2	2.58e-04	7	123	2	19626602
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	KRT78 SRPK2 STK31 LINS1 SERPINI2 MAP1S BAZ1A	3.11e-04	361	123	7	26167880
Pubmed	Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages.	NDOR1 DNMT3A	3.43e-04	8	123	2	26030024
Pubmed	Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.	KLK10 ERCC6 FANCF BRCA2 DNMT3A	3.57e-04	170	123	5	19064572
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	RPS6KA4 SPG7 CFB PDE4DIP CNTNAP2 TSTD2 RUSF1	3.66e-04	371	123	7	15747579
Pubmed	Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.	RPS6KA4 TICAM1	4.39e-04	9	123	2	20362473
Pubmed	IFI16 is an innate immune sensor for intracellular DNA.	TICAM1 IFI16	4.39e-04	9	123	2	20890285
Pubmed	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	FMO3 FMO6P	4.39e-04	9	123	2	22903471
Pubmed	Genetic modifiers of muscular dystrophy: implications for therapy.	ITGA7 NOS1	4.39e-04	9	123	2	16916601
Pubmed	Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.	IREB2 CDKAL1 CFB BRCA2	4.67e-04	101	123	4	20587610
Pubmed	MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells.	TICAM1 CIITA	6.68e-04	11	123	2	22908323
Pubmed	Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis.	NDOR1 ITGB4	6.68e-04	11	123	2	35941116
Pubmed	TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell-independent isotype switch in mice.	TICAM1 CIITA	6.68e-04	11	123	2	23144170
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	KRT78 ITGB4 ARHGEF40 CNTNAP2 MROH7	7.81e-04	202	123	5	33005030
Pubmed	RIPK3 Promotes Mefv Expression and Pyrin Inflammasome Activation via Modulation of mTOR Signaling.	TICAM1 MEFV	8.00e-04	12	123	2	32989095
Pubmed	Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.	ITGA7 ITGB4	8.00e-04	12	123	2	11381080
Pubmed	Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.	ITGA7 ITGB4	8.00e-04	12	123	2	12843252
Pubmed	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.	PDE4DIP CDK5RAP2	9.43e-04	13	123	2	17920017
Pubmed	The DNA sequence of human chromosome 7.	ERV3-1 ADCK2 SRPK2 STK31 PHKG1 SLC25A13 CNTNAP2	1.01e-03	441	123	7	12853948
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	DBN1 CNNM4 MAP1S PPP6C ICAM5 SLC25A13 PRR14L PHLPP2	1.02e-03	573	123	8	28330616
Pubmed	Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases.	MAP1S CIITA	1.10e-03	14	123	2	15964851
Pubmed	Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss.	ERCC6 CFB	1.10e-03	14	123	2	19015224
Pubmed	Comprehensive analysis of DNA repair gene variants and risk of meningioma.	ERCC6 BRCA2 POLQ	1.10e-03	57	123	3	18270339
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	COL9A2 FMO1 FMO2 FMO3 FMO4 OBSCN CSMD2 IFI16 FMO6P SCCPDH TNN	1.11e-03	1031	123	11	16710414
Pubmed	STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.	NDOR1 TICAM1	1.26e-03	15	123	2	29056340
Pubmed	A genome-wide association study on obesity and obesity-related traits.	NRXN3 PCDH9	1.26e-03	15	123	2	21552555
Pubmed	Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.	ITGA7 ITGB4	1.26e-03	15	123	2	15366018
Pubmed	Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.	XDH NOS1	1.26e-03	15	123	2	19505917
Pubmed	Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential.	ITGB4 MUC5AC	1.26e-03	15	123	2	25358791
Pubmed	Hippocampals neurogenesis is impaired in mice with a deletion in the coiled coil domain of Talpid3-implications for Joubert syndrome.	NDOR1 KIAA0586	1.26e-03	15	123	2	35470378
Pubmed	EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.	TENM2 DNMT3A	1.26e-03	15	123	2	26576615
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	ITGA7 MINDY3 RAB11FIP3	1.28e-03	60	123	3	19075228
Pubmed	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.	KRT78 EVPL ITGB4	1.40e-03	62	123	3	26644517
Pubmed	MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.	NRXN3 NOS1	1.63e-03	17	123	2	27779093
Pubmed	H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17.	TAGAP CFB	1.63e-03	17	123	2	6816725
Pubmed	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	ACP7 CDKAL1	1.63e-03	17	123	2	21490949
Pubmed	Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment.	CNTNAP2 PRR14L	1.83e-03	18	123	2	24939585
Pubmed	Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.	ERCC6 FANCF BRCA2	1.83e-03	68	123	3	20496165
Pubmed	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.	DMXL2 KRT78 MROH7 DMBT1	1.98e-03	149	123	4	22664934
Interaction	FMO4 interactions	FMO1 FMO2 FMO4	7.44e-06	7	122	3	int:FMO4
Interaction	FMO2 interactions	FMO2 FMO3 FMO4	1.77e-05	9	122	3	int:FMO2
Interaction	FMO5 interactions	FMO2 FMO3 FMO4	2.52e-05	10	122	3	int:FMO5
Cytoband	1q24.3	FMO1 FMO2 FMO3 FMO4 FMO6P	1.91e-09	20	123	5	1q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1q24	FMO1 FMO2 FMO3 FMO4 FMO6P	2.68e-05	129	123	5	chr1q24
GeneFamily	Fibronectin type III domain containing	INSRR MYOM3 OBSCN ITGB4 TNN	6.40e-04	160	78	5	555
Coexpression	GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_UP	NDOR1 STAB2 LILRB2 EVPL KIFC2 CFB MTMR11 PDZRN3	3.60e-06	192	123	8	M4179
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMXL2 KRT78 HK3 CNNM4 BAZ1A SLC25A13 PNPLA7 POLQ	4.26e-08	182	123	8	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	facs-Pancreas-Exocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 XDH ITGB4 PRKD3 SERPINI2 CUZD1 DMBT1 TNS1	6.70e-08	193	123	8	c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ACP7 VTCN1 EVPL ITGB4 KIFC2 NRXN3 NECTIN4	6.03e-07	176	123	7	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 VTCN1 ITGB4 SERPINI2 CUZD1 DMBT1 TNS1	9.06e-07	187	123	7	9aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell	343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SUSD4 KLK10 FMO2 VTCN1 CFB NECTIN4 MUC5AC	9.72e-07	189	123	7	b06471b1bebb990d5146bddfb8002401c6b099a0
ToppCell	343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SUSD4 KLK10 FMO2 VTCN1 CFB NECTIN4 MUC5AC	9.72e-07	189	123	7	a8246acf31f02c85421268245afb651aa8788f14
ToppCell	Striatum-Macroglia-ASTROCYTE-Gja1\|Striatum / BrainAtlas - Mouse McCarroll V32	FMO1 ERV3-1 MYOM3 SLC1A2 PHKG1 MROH7	9.95e-07	119	123	6	d47880ef1cff036192c43646a04fa8598dd7e1f4
ToppCell	Striatum-Macroglia-ASTROCYTE\|Striatum / BrainAtlas - Mouse McCarroll V32	FMO1 ERV3-1 MYOM3 SLC1A2 PHKG1 MROH7	9.95e-07	119	123	6	0583387cc4497cf991fa42a81f2f66d9c6b774eb
ToppCell	IPF-Epithelial-Goblet\|IPF / Disease state, Lineage and Cell class	SUSD4 KLK10 FMO2 VTCN1 NRXN3 NECTIN4 MUC5AC	1.01e-06	190	123	7	e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCell	IPF-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	SUSD4 KLK10 FMO2 VTCN1 NRXN3 NECTIN4 MUC5AC	1.01e-06	190	123	7	c29dabf0826663b9d6df51a7af9b76592090e44c
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 XDH NRXN3 NECTIN4	1.12e-06	193	123	7	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Epithelial_cells-Club_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	KLK10 FMO2 VTCN1 IFI16 KLHL23 NECTIN4 MUC5AC	1.20e-06	195	123	7	b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 XDH NRXN3 NECTIN4	1.33e-06	198	123	7	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	distal-Epithelial-Mucous-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 FMO2 VTCN1 FMO6P CFB NECTIN4 MUC5AC	1.37e-06	199	123	7	35fb7bd35e53d8ca189fe8c7744211a5201081f6
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	OBSCN TENM2 NRXN3 PDE4DIP PCDH9 PDZRN3 PDZRN4	1.42e-06	200	123	7	c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Crym_(Crym)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	STAB2 FMO4 ERV3-1 MYOM3 VWDE	3.24e-06	82	123	5	bc4e309c0128d126c47895e88d2250324c6ff81a
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Crym_(Crym)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	STAB2 FMO4 ERV3-1 MYOM3 VWDE	3.24e-06	82	123	5	9cd1b8a580566904a1ca0d4b5c48b2bf12a8898b
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Crym_(Crym)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	STAB2 FMO4 ERV3-1 MYOM3 VWDE	3.24e-06	82	123	5	0fb857a83f61d8c26be1b151903f4e6dc69397f9
ToppCell	Club_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SUSD4 KLK10 FMO3 VTCN1 CFB KLHL23	5.75e-06	161	123	6	bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 SUSD4 RYR3 KCNV1 NOS1 PCDH9	5.96e-06	162	123	6	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	SUSD4 KLK10 VTCN1 NRXN3 NECTIN4 MUC5AC	7.09e-06	167	123	6	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DMXL2 LILRB2 OBSCN TENM2 PDE4DIP APBB1IP	7.85e-06	170	123	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 HK3 MEFV SLC25A13 ZBTB5 FITM1	7.85e-06	170	123	6	f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CAPN9 EVPL DBN1 ITGB4 CFB MUC5AC	8.40e-06	172	123	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KLK10 VTCN1 ITGB4 VWDE CFB NECTIN4	8.68e-06	173	123	6	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	FLU-Healthy-3\|FLU / Virus stimulation, Condition and Cluster	COL9A2 LINS1 FDXR SNAPC3 HERC6 RAB11FIP3	8.68e-06	173	123	6	32b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCell	FLU-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	COL9A2 LINS1 FDXR SNAPC3 HERC6 RAB11FIP3	8.68e-06	173	123	6	26e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT78 KLK10 EVPL ITGB4 KCNV1 NECTIN4	8.68e-06	173	123	6	1b2508cc890430bd4b2cf232c633928edb86c57e
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 NRXN3 MUC5AC	8.68e-06	173	123	6	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMXL2 NRG4 CFB BAZ1A CDK5RAP2 APBB1IP	8.97e-06	174	123	6	65147b0f8c2ccadd5685430d31081520c157536a
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 NRXN3 MUC5AC	8.97e-06	174	123	6	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	Healthy_Control-Myeloid-Mast\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	OBSCN EVPL DBN1 ARHGEF40 SIGLEC6 ZBTB5	9.27e-06	175	123	6	ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell	Healthy_Control-Myeloid-Mast-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	OBSCN EVPL DBN1 ARHGEF40 SIGLEC6 ZBTB5	9.27e-06	175	123	6	eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN ITGA7 TENM2 PDE4DIP PCDH9	9.57e-06	176	123	6	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 NRXN3 MUC5AC	1.05e-05	179	123	6	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 ITGB4 SERPINI2 CUZD1 DMBT1 TNS1	1.05e-05	179	123	6	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	Control-Epithelial-Goblet\|Control / Disease state, Lineage and Cell class	SUSD4 KLK10 FMO2 VTCN1 NECTIN4 MUC5AC	1.09e-05	180	123	6	5293d23b8b8ea587239ffde561b70bad01632521
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLK10 VTCN1 EVPL ITGB4 KCNV1 NECTIN4	1.12e-05	181	123	6	6b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN TENM2 PDE4DIP PCDH9 PDZRN3	1.12e-05	181	123	6	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLK10 VTCN1 EVPL ITGB4 KCNV1 NECTIN4	1.12e-05	181	123	6	f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCell	facs-Pancreas-Exocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 ITGB4 SERPINI2 CUZD1 DMBT1 TNS1	1.16e-05	182	123	6	45faefd7cbeac84d2c58650530b902af6ce921f8
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 NRXN3 MUC5AC	1.16e-05	182	123	6	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	wk_20-22-Mesenchymal-Mesothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KLK10 NRG4 STK31 VWDE CFB PDZRN4	1.23e-05	184	123	6	804f8a41cd6b1361448872bf352bf0a38a0fac66
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ACP7 SUSD4 KLK10 VTCN1 EVPL NECTIN4	1.23e-05	184	123	6	fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	MYOM3 OBSCN TENM2 PDE4DIP PCDH9 PDZRN3	1.23e-05	184	123	6	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	wk_20-22-Mesenchymal-Mesothelial-Late_mesothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KLK10 NRG4 STK31 VWDE CFB PDZRN4	1.23e-05	184	123	6	60dd055c2e2e92b838ac649c12e8cccd9c3b1b71
ToppCell	Control-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	SUSD4 KLK10 FMO2 VTCN1 NECTIN4 MUC5AC	1.27e-05	185	123	6	9a793e6016295a63820e9d7563f195494ac692e7
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN TENM2 PDE4DIP PCDH9 PDZRN3	1.27e-05	185	123	6	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	HK3 LILRB2 ITGA7 MEFV MTMR11 PLAGL2	1.31e-05	186	123	6	a16ecf70271894a842925f232009e2623d16947e
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT78 KLK10 MYOM3 EVPL TENM2 NECTIN4	1.35e-05	187	123	6	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	STAB2 FMO4 ERV3-1 MYOM3 SLC1A2	1.43e-05	111	123	5	7d7aad8e9811c67fb9abfb4ebc75def01a517adf
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	STAB2 FMO4 ERV3-1 MYOM3 SLC1A2	1.43e-05	111	123	5	cb45322fbeafec2f1ab7a3727da69abb1047567d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 SUSD4 SLC1A2 RYR3 NOS1 PCDH9	1.43e-05	189	123	6	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	DMXL2 HK3 NRXN3 CIITA PDE4DIP DMBT1	1.43e-05	189	123	6	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 NRXN3 NECTIN4	1.48e-05	190	123	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	Club\|World / shred by cell class for parenchyma	SUSD4 KLK10 FMO2 VTCN1 NECTIN4 MUC5AC	1.48e-05	190	123	6	1974d559d7fee6cb68065b18af8bd38b64910622
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 VTCN1 XDH NECTIN4	1.52e-05	191	123	6	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HK3 TAGAP LILRB2 MEFV CIITA APBB1IP	1.52e-05	191	123	6	79c83a710aa17fc06f286e4ea2011ed9e30e3bc6
ToppCell	Monocytes-Inflammatory_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	DMXL2 HK3 LILRB2 MEFV MTMR11 PLAGL2	1.57e-05	192	123	6	4be5c2c946337cd3e710137726358adca563f146
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FMO2 STAB2 ERV3-1 TSPEAR XDH FMO6P	1.62e-05	193	123	6	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FMO2 FMO3 XDH IFI16 BAZ1A NECTIN4	1.62e-05	193	123	6	463274f394757fb2570ae885d58e1f9fa7e60c4a
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN TENM2 PDE4DIP PCDH9 PDZRN3	1.62e-05	193	123	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KLK10 FMO2 VTCN1 CFB NECTIN4 MUC5AC	1.62e-05	193	123	6	8ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell	Club_cells\|World / lung cells shred on cell class, cell subclass, sample id	KLK10 FMO2 VTCN1 KLHL23 NECTIN4 MUC5AC	1.62e-05	193	123	6	9d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell	343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KLK10 FMO2 VTCN1 CFB NECTIN4 MUC5AC	1.62e-05	193	123	6	0e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCell	NS-critical-d_0-4-Epithelial-Squamous\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KRT78 KLK10 FMO2 XDH EVPL NECTIN4	1.66e-05	194	123	6	614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT78 NDOR1 NRG4 NRXN3 NECTIN4 DMBT1	1.66e-05	194	123	6	715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCell	normal_Lung-Epithelial_cells-Club\|normal_Lung / Location, Cell class and cell subclass	SUSD4 KLK10 FMO2 VTCN1 NECTIN4 MUC5AC	1.71e-05	195	123	6	b46544ad5af04f4dbc2643637caa3d2d50d922ae
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN TENM2 PDE4DIP PCDH9 PDZRN3	1.71e-05	195	123	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Club\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SUSD4 KLK10 FMO2 VTCN1 EVPL NECTIN4	1.76e-05	196	123	6	4e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell	ILEUM-non-inflamed-(8)_Pericytes\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	A2M FMO2 FMO3 ITGA7 KLHL23 TNS1	1.76e-05	196	123	6	b98fe1519e420d8b03c66e164bf4544f3dbb2e44
ToppCell	LAM-Mesenchyme-Mesenchyme\|LAM / Condition, Lineage and Cell class	A2M FMO2 FMO3 ITGA7 KLHL23 PDZRN3	1.76e-05	196	123	6	4590fb157797a68dca4295e203702bbae279cd03
ToppCell	LAM-Mesenchyme\|LAM / Condition, Lineage and Cell class	A2M FMO2 FMO3 ITGA7 KLHL23 PDZRN3	1.76e-05	196	123	6	e7918b0cd5eeb675012f871f43f4388471845035
ToppCell	COVID-19-Heart-Mito_CM\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN ITGA7 TENM2 PDE4DIP FITM1	1.81e-05	197	123	6	44e49943d62bfe622b40ad0460093d31540544df
ToppCell	Fetal_29-31_weeks-Immune-monocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DMXL2 HK3 LILRB2 MEFV CIITA APBB1IP	1.81e-05	197	123	6	48a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCell	critical-Epithelial-Squamous\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KRT78 KLK10 FMO2 TICAM1 XDH NECTIN4	1.81e-05	197	123	6	eccc80d6ab79c46b10108de1cff3abeacfc105cd
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DMXL2 HK3 LILRB2 MEFV CIITA APBB1IP	1.81e-05	197	123	6	8b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	COL9A2 KRT78 FMO2 VTCN1 SLC1A2 HYDIN	1.87e-05	198	123	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SUSD4 KLK10 FMO2 XDH NRXN3 NECTIN4	1.87e-05	198	123	6	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	COL9A2 KRT78 FMO2 VTCN1 SLC1A2 HYDIN	1.87e-05	198	123	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	mLN-(4)_Monocyte\|mLN / shred on region, Cell_type, and subtype	DMXL2 HK3 LILRB2 ITGA7 MEFV MTMR11	1.92e-05	199	123	6	6795ff31f92580195c9db776951f99d647484d24
ToppCell	mLN-Monocyte\|mLN / Region, Cell class and subclass	DMXL2 HK3 LILRB2 ITGA7 MEFV MTMR11	1.92e-05	199	123	6	241f790cd5d8a9b2451333deecc826a673bae70a
ToppCell	Biopsy_Other_PF-Epithelial-MUC5B+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SUSD4 KLK10 FMO2 VTCN1 CFB MUC5AC	1.92e-05	199	123	6	afd0df242a93f176438309668a9487be1250d9ca
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Club\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SUSD4 KLK10 FMO2 VTCN1 XDH MUC5AC	1.92e-05	199	123	6	2b17694cffbec28a2c8f165dfcff6bab94aa0f4c
ToppCell	mLN-Monocyte-Monocyte\|mLN / Region, Cell class and subclass	DMXL2 HK3 LILRB2 ITGA7 MEFV MTMR11	1.92e-05	199	123	6	dcee372774c169a3048bdaed3734b3215bf8ffad
ToppCell	Biopsy_Control_(H.)-Epithelial-MUC5B+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	SUSD4 KLK10 FMO2 VTCN1 CFB MUC5AC	1.92e-05	199	123	6	4ab45996e6bca406c77895a5998982b8ab1cf210
ToppCell	proximal-Epithelial-Mucous-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 VTCN1 FMO6P CFB NECTIN4 MUC5AC	1.92e-05	199	123	6	baac580484124b7c36717b607adcf2cb446e631d
ToppCell	proximal-Epithelial-Mucous\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 VTCN1 FMO6P CFB NECTIN4 MUC5AC	1.92e-05	199	123	6	15ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Club\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SUSD4 KLK10 FMO2 VTCN1 XDH MUC5AC	1.92e-05	199	123	6	111cfd589ec6795075d8d88d7664bfb23eba5bf6
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SUSD4 KLK10 FMO2 VTCN1 XDH MUC5AC	1.92e-05	199	123	6	d583290a1d288b749ad17bc501c1487268c6551c
ToppCell	proximal-3-Epithelial-Mucous\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 VTCN1 FMO6P CFB NECTIN4 MUC5AC	1.92e-05	199	123	6	3018378860de084662be0cc46fce421db3bb9ec9
ToppCell	distal-3-Epithelial-Mucous\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 FMO2 VTCN1 CFB NECTIN4 MUC5AC	1.92e-05	199	123	6	64dc8a9b25cd52935bd3f956b5c65d2fd1bf4bf5
ToppCell	mLN-(4)_Monocyte-(40)_Monocyte\|mLN / shred on region, Cell_type, and subtype	DMXL2 HK3 LILRB2 ITGA7 MEFV MTMR11	1.92e-05	199	123	6	bcbb1eee8d79bf670dbe113094c3a292b135ce2f
ToppCell	distal-Epithelial-Mucous-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SUSD4 KLK10 VTCN1 CFB NECTIN4 MUC5AC	1.92e-05	199	123	6	0af89ef40807fc4ad79ab82a2186ab6e866c6931
ToppCell	distal-Epithelial-Mucous\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SUSD4 KLK10 VTCN1 CFB NECTIN4 MUC5AC	1.92e-05	199	123	6	a7fe7b792d696f369ad0310a772160a1729ef223
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	A2M COL9A2 PDE4DIP TNS1 PCDH9 PDZRN4	1.97e-05	200	123	6	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KRT78 SUSD4 KLK10 FMO2 VTCN1 NRXN3	1.97e-05	200	123	6	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VTCN1 XDH SLC1A2 ITGB4 VWDE DMBT1	1.97e-05	200	123	6	030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	TENM2 NRXN3 PDE4DIP CNTNAP2 PDZRN3 PDZRN4	1.97e-05	200	123	6	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	mLN-Macrophage\|mLN / Region, Cell class and subclass	A2M DMXL2 HK3 LILRB2 MEFV TNS1	1.97e-05	200	123	6	68d709afd226241e002dae6d6820bccd1cfd87a1
Drug	N,N-dimethylaniline-N-oxide	FMO1 FMO2 FMO3 FMO4 FMO6P	1.83e-09	11	122	5	CID000000950
Drug	Ccris 2188	FMO1 FMO2 FMO3 FMO4	3.91e-09	5	122	4	CID000146896
Drug	n-octylamine	FMO1 FMO2 FMO3 XDH FMO6P FDXR	5.90e-08	39	122	6	CID000008143
Drug	Benzydamine	FMO1 FMO2 FMO3	5.98e-07	4	122	3	ctd:D001591
Drug	methyl p-tolyl sulfide	FMO1 FMO2 FMO3 FMO6P	7.54e-07	14	122	4	CID000069334
Drug	TTNPB; Down 200; 0.1uM; MCF7; HG-U133A	STAB2 VTCN1 ITGB4 PRKD3 TNS1 PCDH9 RUSF1 SOS2 RAB11FIP3	1.29e-06	199	122	9	223_DN
Drug	N,N-dimethylaniline	FMO1 FMO2 FMO3 FMO4 FMO6P	2.95e-06	42	122	5	CID000000949
Drug	N-ethyl-N-methylaniline	FMO1 FMO3 FMO4	2.97e-06	6	122	3	CID000011956
Drug	benzydamine N-oxide	FMO1 FMO3 FMO4	5.17e-06	7	122	3	CID000065465
Drug	NADP(H	FMO1 NDOR1 FMO2 FMO3 FMO4 HK3 IREB2 XDH FMO6P NUDT12 SCCPDH FDXR NOS1	5.21e-06	527	122	13	CID000000930
Drug	S-benzyl-L-cysteine	FMO1 FMO2 FMO3 FMO6P	7.67e-06	24	122	4	CID000076454
Drug	Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; HL60; HG-U133A	SPG7 SRPK2 IFI16 PRKD3 MINDY3 ARHGEF40 SCCPDH BRCA2	9.37e-06	192	122	8	1616_UP
Drug	Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	NDOR1 ITGA7 PDE4DIP HERC6 TNS1 PHLPP2 DNMT3A SOS2	1.01e-05	194	122	8	6827_UP
Drug	Scoulerine [6451-73-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ZNF224 CDKAL1 PRKD3 MINDY3 BRCA2 TMEM209 SNAPC3 SOS2	1.01e-05	194	122	8	2891_DN
Drug	thiobenzamide	FMO1 FMO2 FMO3 FMO6P	1.07e-05	26	122	4	CID000683563
Drug	Phensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A	A2M STAB2 XDH CDKAL1 TNS1 NOS1 PDZRN3 RAB11FIP3	1.09e-05	196	122	8	5097_UP
Drug	Isopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A	A2M DMXL2 ERCC6 PRKD3 SIGLEC6 PDE4DIP DNMT3A SOS2	1.09e-05	196	122	8	6781_UP
Drug	PNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A	SUSD4 NDOR1 ADCK2 KCNV1 ARHGEF40 NRXN3 CNTNAP2 TNS1	1.09e-05	196	122	8	3692_UP
Drug	6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; HL60; HT_HG-U133A	LCMT2 FANCF MINDY3 PDE4DIP SNAPC3 HERC6 TNS1 SOS2	1.09e-05	196	122	8	2925_DN
Drug	trimethylamine	FMO1 FMO2 FMO3 FMO4 FMO6P	1.14e-05	55	122	5	CID000001146
Drug	(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	NDOR1 STAB2 XDH PRKD3 SIGLEC6 PDE4DIP DNMT3A SOS2	1.17e-05	198	122	8	6096_DN
Drug	Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; MCF7; HT_HG-U133A	LILRB2 TICAM1 KIAA0586 ZNF557 MINDY3 CIITA PDE4DIP CUZD1	1.17e-05	198	122	8	6239_UP
Drug	TCVC	FMO1 FMO2 FMO3	1.23e-05	9	122	3	CID000108091
Drug	beta-NADP	FMO1 FMO2 FMO3 FMO4 HK3 IREB2 XDH FMO6P NUDT12 QPRT FDXR NOS1	1.32e-05	490	122	12	CID000000929
Drug	theobromine	FMO1 FMO3 FMO4 XDH	1.68e-05	29	122	4	CID000005429
Drug	vitamin B	FMO1 FMO3 XDH ITGA7 NUDT12 TNN QPRT FDXR NOS1	3.09e-05	295	122	9	CID000000936
Drug	p-tolyl sulfoxide	FMO1 FMO2 FMO3	3.19e-05	12	122	3	CID000015680
Drug	pyrazinamide	IREB2 XDH QPRT MUC5AC DNMT3A	3.24e-05	68	122	5	CID000001046
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	LILRB2 ITGA7 NRXN3 PDE4DIP TNS1 PCDH9 RAB11FIP3	4.99e-05	178	122	7	4483_UP
Drug	flavins	FMO1 FMO2 FMO3 FMO4 FDXR NOS1	5.09e-05	122	122	6	CID005326566
Drug	2,4,4'-trichlorobiphenyl	KRT78 ACP7 SUSD4 STAB2 VTCN1 TSPEAR DBN1 CD320 NRXN3 BRCA2 BAZ1A PDE4DIP CNTNAP2 MROH7 NECTIN4 WDR45B FITM1 POLQ PCDH9 PHIP	5.95e-05	1411	122	20	ctd:C081766
Drug	methimazole	FMO1 FMO2 FMO3 FMO4 FMO6P TNS1	6.10e-05	126	122	6	CID001349907
Drug	dichloran	FMO1 FMO3 FMO4 IREB2	6.82e-05	41	122	4	CID000007430
Drug	2,4,5,2',5'-pentachlorobiphenyl	KRT78 ACP7 SUSD4 STAB2 VTCN1 TSPEAR DBN1 CD320 NRXN3 BRCA2 BAZ1A PDE4DIP CNTNAP2 MROH7 NECTIN4 WDR45B FITM1 POLQ PCDH9 PHIP	7.95e-05	1441	122	20	ctd:C009828
Drug	butyl p-tolyl sulfide	FMO1 FMO3	8.51e-05	3	122	2	CID000304040
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	RPS6KA4 DBN1 ITGA7 CDKAL1 BRCA2 TMEM209 HERC6	8.58e-05	194	122	7	1185_DN
Drug	Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HT_HG-U133A	ADCK2 CDKAL1 BRCA2 SIGLEC6 PDE4DIP CNTNAP2 DNMT3A	8.86e-05	195	122	7	4577_UP
Drug	Kawain [500-64-1]; Down 200; 17.4uM; PC3; HT_HG-U133A	ZNF224 CDKAL1 PDE4DIP CUZD1 CDK5RAP2 PCDH9 RUSF1	8.86e-05	195	122	7	3670_DN
Drug	Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A	COL9A2 CDKAL1 PDE4DIP NOS1 PHLPP2 DNMT3A SOS2	8.86e-05	195	122	7	2245_DN
Drug	(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A	DMXL2 SLC1A2 ITGB4 CDKAL1 MAP1S PDE4DIP PRR14L	8.86e-05	195	122	7	2855_UP
Drug	Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A	NDOR1 STAB2 XDH ADCK2 EVPL TNS1 MUC5AC	8.86e-05	195	122	7	2833_UP
Drug	Mephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A	LILRB2 LINS1 CUZD1 TMEM209 SNAPC3 SOS2 RAB11FIP3	8.86e-05	195	122	7	3580_DN
Drug	Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A	A2M DMXL2 STAB2 IREB2 SLC1A2 CDKAL1 DNMT3A	8.86e-05	195	122	7	3327_UP
Drug	Methyldopa (L,-) [555-30-6]; Up 200; 19uM; HL60; HG-U133A	SPG7 ITGA7 IFI16 FANCF MINDY3 SOS2 RAB11FIP3	8.86e-05	195	122	7	1619_UP
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; PC3; HT_HG-U133A	FMO4 IFI16 MINDY3 PDE4DIP CNTNAP2 PCDH9 SOS2	8.86e-05	195	122	7	4664_DN
Drug	Tolazamide [1156-19-0]; Up 200; 12.8uM; PC3; HT_HG-U133A	WRNIP1 SIGLEC6 CNTNAP2 TNS1 PHLPP2 DNMT3A SOS2	8.86e-05	195	122	7	4003_UP
Drug	Sulfaphenazole [526-08-9]; Down 200; 12.8uM; PC3; HT_HG-U133A	RPS6KA4 TICAM1 KIAA0586 ITGB4 CNNM4 MAP1S BRCA2	9.15e-05	196	122	7	1794_DN
Drug	Benzbromarone [3562-84-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	CAPN9 SIGLEC6 PDE4DIP CNTNAP2 TMEM209 SNAPC3 SOS2	9.15e-05	196	122	7	5015_DN
Drug	Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A	XDH ITGA7 ITGB4 MINDY3 ICAM5 TNS1 RUSF1	9.15e-05	196	122	7	3238_UP
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; HL60; HT_HG-U133A	XDH ADCK2 SRPK2 CD320 TMEM209 TNS1 NOS1	9.15e-05	196	122	7	1311_UP
Drug	Bisoprolol fumarate; Down 200; 9uM; PC3; HT_HG-U133A	CDKAL1 MINDY3 NRXN3 CNTNAP2 HERC6 TNS1 SOS2	9.15e-05	196	122	7	6748_DN
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; HL60; HT_HG-U133A	A2M COL9A2 LILRB2 ITGB4 LINS1 PDE4DIP NOS1	9.15e-05	196	122	7	2207_DN
Drug	Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; MCF7; HT_HG-U133A	KIAA0586 ADCK2 LINS1 TMEM209 CDK5RAP2 PRR14L PCDH9	9.15e-05	196	122	7	7429_DN
Drug	Indapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT_HG-U133A	A2M DMXL2 ITGA7 PDE4DIP CNTNAP2 PRR14L DNMT3A	9.15e-05	196	122	7	4335_UP
Drug	Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A	STAB2 XDH PDE4DIP CUZD1 TMEM209 PHLPP2 DNMT3A	9.15e-05	196	122	7	6824_UP
Drug	Isosorbide dinitrate [87-33-2]; Down 200; 17uM; HL60; HT_HG-U133A	XDH ADCK2 DBN1 MINDY3 PDE4DIP RUSF1 SOS2	9.15e-05	196	122	7	2183_DN
Drug	Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A	CAPN9 ITGA7 ITGB4 NRXN3 CIITA CNTNAP2 DNMT3A	9.15e-05	196	122	7	5606_UP
Drug	Pyrimethamine [58-14-0]; Up 200; 16uM; PC3; HG-U133A	IFI16 CNNM4 MINDY3 MTMR11 MAP1S BRCA2 SIGLEC6	9.15e-05	196	122	7	1894_UP
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	A2M STAB2 ADCK2 IFI16 MINDY3 CIITA PDE4DIP	9.15e-05	196	122	7	5593_UP
Drug	alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A	COL9A2 NDOR1 KLK10 CNNM4 PHKG1 ICAM5 FDXR	9.15e-05	196	122	7	2670_UP
Drug	Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; PC3; HT_HG-U133A	A2M ITGA7 PHKG1 SIGLEC6 PDE4DIP CNTNAP2 NOS1	9.15e-05	196	122	7	3996_UP
Drug	Trioxsalen [3902-71-4]; Down 200; 17.6uM; HL60; HT_HG-U133A	DMXL2 FMO4 LILRB2 CDKAL1 SNAPC3 TNS1 SOS2	9.15e-05	196	122	7	2516_DN
Drug	Sertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A	FMO4 EVPL MAP1S TMEM209 SNAPC3 POLQ DNMT3A	9.44e-05	197	122	7	3550_DN
Drug	Cloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; PC3; HT_HG-U133A	ITGB4 MINDY3 SCCPDH NSUN3 BRCA2 PDE4DIP SNAPC3	9.44e-05	197	122	7	2126_DN
Drug	Spaglumic acid [4910-46-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	FMO4 KIAA0586 CDKAL1 ZNF557 SIGLEC6 TMEM209 DNMT3A	9.44e-05	197	122	7	7465_DN
Drug	Androsterone [53-41-8]; Up 200; 13.8uM; PC3; HT_HG-U133A	COL9A2 FMO3 IREB2 ADCK2 ITGB4 PDE4DIP HERC6	9.44e-05	197	122	7	4635_UP
Drug	Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A	DMXL2 LILRB2 ITGA7 ARHGEF40 CNTNAP2 TNS1 PCDH9	9.44e-05	197	122	7	6091_UP
Drug	rapamycin; Down 200; 0.1uM; HL60; HG-U133A	LILRB2 ADCK2 SRPK2 CDKAL1 ZNF557 CNNM4 QPRT	9.44e-05	197	122	7	362_DN
Drug	Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; PC3; HT_HG-U133A	NDOR1 LILRB2 WRNIP1 ITGA7 NRXN3 ICAM5 PDE4DIP	9.44e-05	197	122	7	5753_UP
Drug	Pergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	COL9A2 ADCK2 PRKD3 MINDY3 MAP1S PDE4DIP RAB11FIP3	9.44e-05	197	122	7	7434_DN
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A	RPS6KA4 EVPL ITGB4 PRKD3 LINS1 CUZD1 TMEM209	9.44e-05	197	122	7	4363_DN
Drug	Methylatropine nitrate [52-88-0]; Up 200; 11uM; PC3; HT_HG-U133A	ITGA7 CDKAL1 PRKD3 MTMR11 NRXN3 PDE4DIP TNS1	9.44e-05	197	122	7	7253_UP
Drug	beta-Glucans	FMO2 FMO3 FMO4	9.66e-05	17	122	3	ctd:D047071
Drug	novobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A	STAB2 BRCA2 CIITA CDK5RAP2 TNS1 SOS2 RAB11FIP3	9.75e-05	198	122	7	437_UP
Drug	Meticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A	NDOR1 LILRB2 CDKAL1 SIGLEC6 PDE4DIP CNTNAP2 NOS1	9.75e-05	198	122	7	7282_UP
Drug	Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A	FMO4 ZNF224 PRKD3 FANCF MTMR11 PDE4DIP PLAGL2	9.75e-05	198	122	7	1799_UP
Drug	Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A	CAPN9 XDH ADAM29 SLC1A2 PRKD3 CNTNAP2 MUC5AC	9.75e-05	198	122	7	2269_UP
Drug	Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	A2M STAB2 DBN1 CDKAL1 PDE4DIP CDK5RAP2 TNS1	9.75e-05	198	122	7	6800_UP
Drug	Doxylamine succinate [562-10-7]; Up 200; 10.2uM; PC3; HT_HG-U133A	WRNIP1 CNNM4 SIGLEC6 QPRT CNTNAP2 TNS1 PDZRN3	9.75e-05	198	122	7	4235_UP
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A	CAPN9 A2M STAB2 EVPL DBN1 CDKAL1 DNMT3A	9.75e-05	198	122	7	4133_DN
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	XDH ZNF557 BRCA2 SIGLEC6 CDK5RAP2 RUSF1 SOS2	9.75e-05	198	122	7	7023_UP
Drug	Suxibuzone [27470-51-5]; Up 200; 9.2uM; PC3; HT_HG-U133A	COL9A2 CNNM4 PHKG1 SERPINI2 PDE4DIP SOS2 RAB11FIP3	1.01e-04	199	122	7	5806_UP
Drug	Condelphine [7633-69-4]; Up 200; 8.8uM; PC3; HT_HG-U133A	STAB2 ADCK2 SIGLEC6 CUZD1 HERC6 PHLPP2 RAB11FIP3	1.01e-04	199	122	7	6357_UP
Drug	Quinic acid [86-68-0]; Up 200; 19.6uM; HL60; HT_HG-U133A	RPS6KA4 SPG7 TICAM1 CNNM4 BRCA2 PLAGL2 SOS2	1.01e-04	199	122	7	2978_UP
Drug	Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; HL60; HT_HG-U133A	MINDY3 SERPINI2 MAP1S CDK5RAP2 PLAGL2 TNS1 PHLPP2	1.01e-04	199	122	7	2940_DN
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SLC1A2 ITGB4 PRKD3 SIGLEC6 CNTNAP2 CUZD1 SOS2	1.01e-04	199	122	7	3638_DN
Drug	Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; HL60; HG-U133A	ERCC6 SRPK2 ZNF224 IFI16 PRKD3 MINDY3 SNAPC3	1.01e-04	199	122	7	1987_UP
Drug	Propranolol hydrochloride [318-98-9]; Down 200; 13.6uM; HL60; HT_HG-U133A	DMXL2 STAB2 ERCC6 ADCK2 ITGB4 PDE4DIP RAB11FIP3	1.01e-04	199	122	7	3059_DN
Drug	Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; HL60; HG-U133A	FMO4 SPG7 LILRB2 MINDY3 MTMR11 PRR14L RAB11FIP3	1.01e-04	199	122	7	1442_UP
Drug	Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A	COL9A2 FMO4 KIAA0586 PRKD3 MAP1S CDK5RAP2 RUSF1	1.04e-04	200	122	7	1682_DN
Drug	Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	CAPN9 A2M LILRB2 TICAM1 ADCK2 SERPINI2 CUZD1	1.04e-04	200	122	7	3866_UP
Drug	manganese sulfate	WRNIP1 SLC1A2 NOS1	1.15e-04	18	122	3	ctd:C039798
Drug	IDPN	FMO1 FMO3 CFB	1.60e-04	20	122	3	CID000008149
Drug	C1-N	A2M CFB	1.70e-04	4	122	2	CID005494413
Drug	demeton-O	FMO1 FMO3	1.70e-04	4	122	2	CID000009273
Drug	benzydamine	FMO1 FMO3 FMO4	2.15e-04	22	122	3	CID000012555
Drug	beta-tocotrienol	CD320 CFB	2.82e-04	5	122	2	CID005282348
Drug	senkirkine	FMO3 FMO4 XDH TENM2	3.23e-04	61	122	4	ctd:C009238
Drug	hydroxylamine	A2M FMO1 FMO3 IREB2 SLC1A2 QPRT NOS1	3.51e-04	244	122	7	CID000000787
Drug	5-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamate	FMO1 FMO4 XDH	4.00e-04	27	122	3	ctd:C521334
Disease	Malignant neoplasm of breast	KLK10 ERCC6 HK3 TICAM1 OBSCN XDH DBN1 CNNM4 C5orf34 BRCA2 ICAM5 MROH7 FASTKD3 TNS1 RUSF1 DNMT3A	9.39e-06	1074	122	16	C0006142
Disease	Methionine sulfoxide measurement	FMO1 FMO2 FMO4	1.48e-05	12	122	3	EFO_0021650
Disease	S-methylcysteine measurement	FMO3 FMO6P	1.70e-05	2	122	2	EFO_0800054
Disease	peritonitis (biomarker_via_orthology)	A2M XDH	3.51e-04	7	122	2	DOID:8283 (biomarker_via_orthology)
Disease	Autism Spectrum Disorders	NRXN3 CNTNAP2 PCDH9 DNMT3A	4.35e-04	85	122	4	C1510586
Disease	left ventricular structural measurement	STAB2 CNTNAP2 PHIP PDZRN3	4.96e-04	88	122	4	EFO_0008205
Disease	niacinamide measurement	FMO2 FMO4	1.09e-03	12	122	2	EFO_0010511
Disease	Fanconi anemia	FANCF BRCA2	1.49e-03	14	122	2	cv:C0015625
Disease	lentiform nucleus measurement	FMO3 FMO6P	1.49e-03	14	122	2	EFO_0004913
Disease	acute lymphoblastic leukemia (is_implicated_in)	MEFV CFB DNMT3A	1.55e-03	55	122	3	DOID:9952 (is_implicated_in)
Disease	Schizoaffective disorder-bipolar type	STAB2 NRXN3	1.96e-03	16	122	2	EFO_0009965
Disease	metabolite measurement	FMO1 FMO2 FMO3 FMO4 DHRS4L1 CDKAL1 ZNF557 RAB11FIP3	2.33e-03	560	122	8	EFO_0004725
Disease	smoking cessation	RPS6KA4 IREB2 SRPK2 TENM2 NRXN3 PPP6C	2.37e-03	325	122	6	EFO_0004319
Disease	Age-related macular degeneration	ERCC6 CFB	2.48e-03	18	122	2	cv:C0242383
Disease	Bone marrow hypocellularity	FANCF BRCA2	2.48e-03	18	122	2	C1855710
Disease	Profound Mental Retardation	LINS1 WDR45B PHIP DNMT3A	2.70e-03	139	122	4	C0020796
Disease	Mental Retardation, Psychosocial	LINS1 WDR45B PHIP DNMT3A	2.70e-03	139	122	4	C0025363
Disease	Mental deficiency	LINS1 WDR45B PHIP DNMT3A	2.70e-03	139	122	4	C0917816
Disease	common carotid intimal medial thickness	RYR3 KLHL23 CNTNAP2	2.72e-03	67	122	3	EFO_0004860
Disease	stomach cancer (is_implicated_in)	CAPN9 ERCC6 DNMT3A	3.34e-03	72	122	3	DOID:10534 (is_implicated_in)
Disease	haptoglobin measurement	HYDIN PHLPP2	3.38e-03	21	122	2	EFO_0004640
Disease	stem Cell Growth Factor beta measurement	STAB2 CNTNAP2 PCDH9	3.75e-03	75	122	3	EFO_0008292
Disease	Carcinoma of lung	ERCC6 BRCA2	4.05e-03	23	122	2	C0684249

Protein segments in the cluster

Peptide	Gene	Start	Entry
VEGDPESLVSLSTCF	ADAM29	106	Q9UKF5
KAFTDPVGELTCLGQ	ERV3-1	351	Q14264
SILSFENREPVGSGC	ADCK2	196	Q7Z695
LPTELCGFQGAEVLS	ARHGEF40	631	Q8TER5
LCDEGFLGTQGSETI	CSMD2	716	Q7Z408
FDLVIGGSPCNDLSI	DNMT3A	701	Q9Y6K1
GQDFSLDLRSTGICP	CIITA	856	P33076
EPDLSCDTAVILGQG	FDXR	171	P22570
ESFCGTSIIVPELEG	APBB1IP	301	Q7Z5R6
TEGGCPDTTFIEDAV	ANKIB1	636	Q9P2G1
VFCSPTVIQDGGLFE	DMXL2	1321	Q8TDJ6
GPEELSVISGNGECS	ERCC6	1116	Q03468
FNSLLCPSGGEVSEE	A2M	916	P01023
LVGNDSEGPLCELLF	BAZ1A	461	Q9NRL2
LEEDVTVPGTLSGCS	CDK5RAP2	6	Q96SN8
QGIPEGAFDEVTSCL	MROH7	406	Q68CQ1
LTCSQDTLGSGDLPF	PDZRN3	606	Q9UPQ7
LVSGEYIDSDCIGNP	PDZRN4	606	Q6ZMN7
GSEAELSPETLCNGQ	RAB11FIP3	396	O75154
EVVGCELTGSSNPFV	IREB2	316	P48200
TGARCEEVFLPGSSI	NRG4	41	Q8WWG1
IITGSAGCEERLTPF	ACP7	366	Q6ZNF0
DISEVVTPRFLCTGG	CFB	671	P00751
SALEQFEGGPCAVIA	MINDY3	41	Q9H8M7
DFTFAPTGQECGLLV	NSUN3	301	Q9H649
TCKAQDGDFEVPGLS	FANCF	331	Q9NPI8
LEPTCFEKSNDIGGL	FMO3	26	P31513
FFGGDEVQPECELIT	LINS1	361	Q8NG48
CLEETGELLLQTGGF	MAP1S	121	Q66K74
AQTPGSVEEDALLCG	MGME1	66	Q9BQP7
GLEPELSGTLICTNF	MTMR11	61	A4FU01
SSDELGCGTNEILPE	CD320	161	Q9NPF0
GCGTNEILPEGDATT	CD320	166	Q9NPF0
GEPEDSLGIVSFLCS	DHRS4L1	246	P0CG22
SEEAPLTGGLQTQSC	PPP1R2C	186	O14990
LDSSVFCSEGEGEPL	KCNV1	21	Q6PIU1
EGEPLALGDCFTVNV	KCNV1	31	Q6PIU1
VGSERPVSCTLDGLF	ICAM5	241	Q9UMF0
ELPLDNTFVGGCDTL	PCDH9	966	Q9HC56
VTTSGPCGEESVLLD	EVPL	1726	Q92817
LEPTCFERSDDIGGL	FMO4	26	P31512
INEICPESGGVSSEF	HERC6	706	Q8IVU3
DFVECEPSTTGGELV	NRXN3	1326	Q9Y4C0
LSGSQQGLEPVFEAC	KRT78	151	Q8N1N4
CLGEVTFNGEPSSLG	PRKD3	321	O94806
APGESLTLQCVSDVG	LILRB2	236	Q8N423
ATGRPECFLTIQEGL	MPHOSPH10	21	O00566
LEPTCFERSDDVGGL	FMO6P	26	O60774
DLREPALGQGSFSVC	RPS6KA4	411	O75676
EASGGITLDNLPQFC	QPRT	246	Q15274
DGPQRFDSCIIVLGS	MEFV	631	O15553
EGDITCSVGFIPVDG	MUC5AC	726	P98088
LPAGEGCATLLNFDE	DBN1	521	Q16643
QGEETLSCSEEGLPG	HK3	11	P52790
APEGGFDAILQTAVC	ITGB4	231	P16144
IGSQEDTCLFLTRPG	PNPLA7	511	Q6ZV29
EPLVIFVCATTGQGD	NDOR1	51	Q9UHB4
LLEIGGLEFSACPFS	NOS1	576	P29475
EGEDAQFTCTIEGAP	OBSCN	6121	Q5VST9
ENITLSGEGIFPQIC	HYDIN	1481	Q4G0P3
FQLVGGSASECDTIP	TTC26	346	A0AVF1
LDGLFTDITLQCPSG	KLHL23	31	Q8NBE8
FITPEADSLSCLQEG	BRCA2	701	P51587
EDLTGSCFEPLPQGL	FITM1	146	A5D6W6
ITIATDIICGFPGET	CDKAL1	356	Q5VV42
GTLPVTFRCLEENLG	SLC1A2	366	P43004
LLELNGIGFSTAECE	POLQ	2086	O75417
LEPTCFERSDDLGGL	FMO1	26	Q01740
GTIQGLEGSADFLCP	COL9A2	161	Q14055
TCFELAPKSGNTGEL	IFI16	736	Q16666
GFGLDTVEVCPSLDI	INSRR	21	P14616
LEPTCFERTEDIGGV	FMO2	26	Q99518
QGELVESNCGASPLT	CNTNAP2	1206	Q9UHC6
NRTGGLFACPLSLEE	ITGA7	86	Q13683
PDGSCESENIKVFDG	CUZD1	81	Q86UP6
NPEFILGGATRTDIC	CAPN9	76	O14815
DGSTLQLSPCGSEFL	C5orf34	21	Q96MH7
GPITLDDVECSGTES	DMBT1	1946	Q9UGM3
FLSVQLGAEESCGGP	KIFC2	91	Q96AC6
GPESRTISLENCGFE	PRR14L	351	Q5THK1
LTDFGFSCQLEPGER	PHKG1	166	Q16816
GLETPLCSEQFGSGE	RUSF1	6	Q96GQ5
IGLVSLCEDEPSSSG	SOS2	181	Q07890
FDQPLSIICGDSDTL	TAGAP	86	Q8N103
NGASCIDISGEPQFL	SCCPDH	116	Q8NBX0
DFVECEPSTGGELVI	NRXN3	321	Q9HDB5
LGGPVFSQVSDCDRL	FASTKD3	76	Q14CZ7
LPQVGSAEEGDFTCR	SIGLEC6	306	O43699
GTNFTLAELGICEPS	TENM2	76	Q9NT68
SEVVAGTGEQCLPFD	TENM2	1326	Q9NT68
TCLAGFIEPGETIED	NUDT12	351	Q9BQG2
FGTEPNAVIAICADG	WDR45B	301	Q5MNZ6
CVSDLQIGGEFSNTP	SNAPC3	221	Q92966
ELTPGFSGADIANIC	SPG7	511	Q9UQ90
QCEISGTPFSNGEKL	PLAGL2	41	Q9UPG8
IEPCQLTEDFGGSLT	SESTD1	136	Q86VW0
VDSGDGVTCTVPIFE	ACTRT1	156	Q8TDG2
TPFVEECLVAAAGGT	SLC25A13	196	Q9UJS0
KSCGTNPDGIIFVSE	CNNM4	56	Q6P4Q7
VLDEGCFTTPASLNG	STK31	396	Q9BXU1
TLGLCGTFDENPEND	VWDE	561	Q8N2E2
EKSSFQCENPEVGLG	ZBTB5	306	O15062
GQNFETCSPLSEDIG	MIXL1	201	Q9H2W2
EELGTSVPLTDGECR	PHIP	1131	Q8WWQ0
CLDGNFLTTLPEELG	PHLPP2	351	Q6ZVD8
EEGFTGLDCAQVVTP	TNN	251	Q9UQP3
LCELFRTGGQVPDTN	PPP6C	61	O00743
EGLGNRLCFLEPTSE	RYR3	41	Q15413
TFCEDFQVPGRGELS	TICAM1	426	Q8IUC6
ACGSVLSEGSPLTEQ	SRPK2	466	P78362
QLTGGFDDLQVCADP	SUSD4	46	Q5VX71
GDSQTSVCITIEPGL	TNS1	226	Q9HBL0
NITEIFSGGCDLSGI	SERPINI2	306	O75830
LIDPTLGGRCDTFTT	STAB2	1881	Q8WWQ8
ISADDVPGSNITGIC	XDH	636	P47989
ISCFNPDELISGQGS	TSTD2	151	Q5T7W7
GCPELQIGEASITSL	TMEM209	366	Q96SK2
ECGTITLIGATTENP	WRNIP1	346	Q96S55
AGVFSLTTDCGLPVD	TSPEAR	166	Q8WU66
IGETPELCALTGPFE	LCMT2	126	O60294
KEGDFPCQTEAGLSV	ZNF224	126	Q9NZL3
TEERGILSGTCPDVE	ZNF557	96	Q8N988
DKPISEGEILFSCGQ	KIAA0586	1226	Q9BVV6
GNIGEDGILSCTFEP	VTCN1	46	Q7Z7D3
QSDSGGPLVCDETLQ	KLK10	226	O43240
DPETGTGLLCIEELS	MYOM3	1166	Q5VTT5
ACSFPGLEAQGTEVL	PDE4DIP	2211	Q5VU43
TGRCPAGELETSDVV	NECTIN4	26	Q96NY8