Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH12 DNAH5 DNAH11	7.59e-05	18	93	3	GO:0008569
GeneOntologyMolecularFunction	1,4-alpha-oligoglucan phosphorylase activity	MTAP PYGB	2.13e-04	5	93	2	GO:0004645
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH12 DNAH5 DNAH11	2.94e-04	28	93	3	GO:0051959
GeneOntologyBiologicalProcess	microtubule-based process	CWH43 CDC42BPA CLASP1 DNAAF4 XPO1 DCX DNAH12 CFAP221 MID1 VPS13A PKD2 KLHL42 DNAI7 CDC20 TUBD1 DNAH5 MOS CFAP46 DNAH11	2.05e-07	1058	93	19	GO:0007017
GeneOntologyBiologicalProcess	epithelial cilium movement involved in extracellular fluid movement	CWH43 DNAAF4 CFAP221 DNAH5 DNAH11	6.91e-06	59	93	5	GO:0003351
GeneOntologyBiologicalProcess	extracellular transport	CWH43 DNAAF4 CFAP221 DNAH5 DNAH11	8.83e-06	62	93	5	GO:0006858
GeneOntologyBiologicalProcess	cilium movement	CWH43 DNAAF4 DNAH12 CFAP221 VPS13A DNAH5 CFAP46 DNAH11	2.38e-05	261	93	8	GO:0003341
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	CDC42BPA CLASP1 DNAAF4 XPO1 DCX MID1 PKD2 CDC20 TUBD1 DNAH5 MOS CFAP46	9.35e-05	720	93	12	GO:0000226
GeneOntologyCellularComponent	cytoplasmic region	CLASP1 PIK3R4 DNAH12 CFAP221 PKD2 DNAI7 DNAH5 CFAP46 DNAH11	3.54e-05	360	94	9	GO:0099568
GeneOntologyCellularComponent	axoneme	PIK3R4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	4.17e-05	207	94	7	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	PIK3R4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	4.30e-05	208	94	7	GO:0097014
GeneOntologyCellularComponent	microtubule associated complex	DCX DNAH12 MID1 DNAI7 DNAH5 DNAH11	8.85e-05	161	94	6	GO:0005875
GeneOntologyCellularComponent	dynein complex	DNAH12 DNAI7 DNAH5 DNAH11	1.02e-04	54	94	4	GO:0030286
GeneOntologyCellularComponent	organelle membrane contact site	APOO PIK3R4 ESYT3 VPS13A	1.26e-04	57	94	4	GO:0044232
GeneOntologyCellularComponent	microtubule	MID2 CLASP1 DCX IQGAP1 DNAH12 MID1 DNAI7 TUBD1 DNAH5 DNAH11	1.42e-04	533	94	10	GO:0005874
GeneOntologyCellularComponent	axonemal dynein complex	DNAH12 DNAI7 DNAH5	1.88e-04	25	94	3	GO:0005858
GeneOntologyCellularComponent	9+0 motile cilium	DNAH5 DNAH11	2.97e-04	6	94	2	GO:0097728
GeneOntologyCellularComponent	basal cortex	CLASP1 PKD2	4.14e-04	7	94	2	GO:0045180
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	PIK3R4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	5.72e-04	317	94	7	GO:0032838
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	SPOPL KLHL42 SPOP	7.16e-04	39	94	3	GO:0031463
GeneOntologyCellularComponent	inner dynein arm	DNAH12 DNAI7	8.79e-04	10	94	2	GO:0036156
GeneOntologyCellularComponent	low-density lipoprotein particle	PLA2G7 APOO	2.30e-03	16	94	2	GO:0034362
GeneOntologyCellularComponent	cilium	DNAAF4 PIK3R4 DNAH12 CFAP221 VPS13A PKD2 DNAI7 TUBD1 DNAH5 CFAP46 DNAH11	2.31e-03	898	94	11	GO:0005929
GeneOntologyCellularComponent	azurophil granule membrane	DNAJC13 ABCA13 NCSTN	2.39e-03	59	94	3	GO:0035577
HumanPheno	Female infertility	DNAAF4 CFAP221 CDC20 DNAH5 MOS DNAH11	2.59e-05	84	37	6	HP:0008222
HumanPheno	Decreased fertility in females	DNAAF4 CFAP221 CDC20 DNAH5 MOS DNAH11	8.71e-05	104	37	6	HP:0000868
HumanPheno	Polysplenia	DNAAF4 CFAP221 DNAH5 CDON DNAH11	9.91e-05	66	37	5	HP:0001748
HumanPheno	Recurrent upper and lower respiratory tract infections	DNAAF4 STAT3 CFAP221 DNAH5 DNAH11	1.14e-04	68	37	5	HP:0002873
HumanPheno	Recurrent sinopulmonary infections	DNAAF4 STAT3 CFAP221 DNAH5 DNAH11	1.14e-04	68	37	5	HP:0005425
HumanPheno	Productive cough	DNAAF4 STAT3 CFAP221 DNAH5 DNAH11	1.14e-04	68	37	5	HP:0031245
MousePheno	abnormal digestive organ placement	TCF7L2 DNAAF4 PKD2 DNAH5 DNAH11	1.15e-05	57	73	5	MP:0003283
MousePheno	right-sided isomerism	DNAAF4 PKD2 DNAH5 DNAH11	1.69e-05	30	73	4	MP:0000508
MousePheno	right-sided stomach	DNAAF4 PKD2 DNAH5 DNAH11	1.94e-05	31	73	4	MP:0010808
MousePheno	biventricular, ambiguous atrioventricular connection	DNAH5 DNAH11	2.69e-05	2	73	2	MP:0011511
MousePheno	abnormal inferior vena cava morphology	TCF7L2 DNAAF4 TULP4 DNAH5 DNAH11	2.73e-05	68	73	5	MP:0006063
MousePheno	abnormal stomach position or orientation	DNAAF4 PKD2 DNAH5 DNAH11	3.55e-05	36	73	4	MP:0010807
MousePheno	right atrial isomerism	DNAAF4 DNAH5 DNAH11	3.76e-05	13	73	3	MP:0006061
MousePheno	abnormal vena cava morphology	TCF7L2 DNAAF4 TULP4 DNAH5 DNAH11	4.99e-05	77	73	5	MP:0006062
MousePheno	muscular ventricular septal defect	TCF7L2 DNAAF4 SALL4 TULP4 DNAH11	4.99e-05	77	73	5	MP:0010420
MousePheno	abnormal interventricular septum muscular part morphology	TCF7L2 DNAAF4 SALL4 TULP4 DNAH11	5.64e-05	79	73	5	MP:0010498
MousePheno	ventricular septal defect	TCF7L2 DNAAF4 SALL4 PTK7 TULP4 PKD2 DNAH5 DNAH11	6.25e-05	261	73	8	MP:0010402
MousePheno	abdominal situs ambiguus	DNAAF4 DNAH5 DNAH11	7.29e-05	16	73	3	MP:0011250
MousePheno	biventricular, discordant atrioventricular connection	DNAH5 DNAH11	8.04e-05	3	73	2	MP:0011510
MousePheno	immotile respiratory cilia	DNAAF4 DNAH5 DNAH11	8.82e-05	17	73	3	MP:0011649
MousePheno	abnormal heart atrium arrangement	DNAAF4 DNAH5 DNAH11	8.82e-05	17	73	3	MP:0014319
MousePheno	double outlet right ventricle	TCF7L2 DNAAF4 PTK7 TULP4 DNAH5 DNAH11	1.30e-04	150	73	6	MP:0000284
MousePheno	dextrocardia	DNAAF4 PKD2 DNAH5 DNAH11	1.42e-04	51	73	4	MP:0000644
MousePheno	mesocardia	PKD2 DNAH5 DNAH11	1.46e-04	20	73	3	MP:0000650
MousePheno	abdominal situs abnormality	DNAAF4 DNAH5 DNAH11	1.70e-04	21	73	3	MP:0031284
MousePheno	abnormal subclavian artery morphology	TCF7L2 TULP4 DNAH5 DNAH11	2.05e-04	56	73	4	MP:0003395
MousePheno	abnormal lung position or orientation	DNAAF4 PKD2 DNAH5 DNAH11	2.19e-04	57	73	4	MP:0010853
MousePheno	situs inversus totalis	DNAAF4 DNAH5 DNAH11	2.24e-04	23	73	3	MP:0011252
MousePheno	situs inversus	DNAAF4 PKD2 DNAH5 DNAH11	2.68e-04	60	73	4	MP:0002766
MousePheno	abnormal vein morphology	TCF7L2 DNAAF4 TULP4 PKD2 DNAH5 DNAH11	3.10e-04	176	73	6	MP:0002725
MousePheno	abnormal interventricular septum morphology	TCF7L2 DNAAF4 SALL4 PTK7 TULP4 PKD2 DNAH5 DNAH11	3.98e-04	342	73	8	MP:0000281
MousePheno	abnormal blood vessel morphology	MYH11 TCF7L2 DNAAF4 NCSTN PTK7 JAK1 NBAS MTAP TULP4 UBR5 VASH2 PKD2 CSTF3 CCDC25 DNAI7 DNAH5 CDON DNAH11	4.40e-04	1472	73	18	MP:0001614
MousePheno	abnormal respiratory motile cilium physiology	DNAAF4 DNAH5 DNAH11	4.53e-04	29	73	3	MP:0011055
MousePheno	left pulmonary isomerism	PKD2 DNAH5 DNAH11	5.53e-04	31	73	3	MP:0003178
MousePheno	small tail bud	BRWD3 MTHFD1	5.55e-04	7	73	2	MP:0012062
MousePheno	superior-inferior ventricles	DNAH5 DNAH11	5.55e-04	7	73	2	MP:0011254
MousePheno	situs inversus with levocardia	DNAH5 DNAH11	5.55e-04	7	73	2	MP:0011253
MousePheno	abnormal heart position or orientation	DNAAF4 PKD2 DNAH5 DNAH11	5.98e-04	74	73	4	MP:0006065
MousePheno	abnormal heart and great artery attachment	TCF7L2 DNAAF4 PTK7 TULP4 DNAH5 DNAH11	6.95e-04	205	73	6	MP:0010426
MousePheno	dual inferior vena cava	TULP4 DNAH5 DNAH11	7.28e-04	34	73	3	MP:0011683
MousePheno	left-sided isomerism	PKD2 DNAH5 DNAH11	7.28e-04	34	73	3	MP:0000542
MousePheno	left atrial isomerism	DNAH5 DNAH11	7.38e-04	8	73	2	MP:0008461
MousePheno	abnormal heart and great vessel attachment	TCF7L2 DNAAF4 PTK7 TULP4 DNAH5 DNAH11	7.50e-04	208	73	6	MP:0010425
MousePheno	abnormal heart septum morphology	TCF7L2 DNAAF4 SALL4 PTK7 TULP4 PKD2 DNAH5 DNAH11	9.12e-04	388	73	8	MP:0006113
MousePheno	abnormal Purkinje cell innervation	CACNA1A PLCB4	9.46e-04	9	73	2	MP:0003894
MousePheno	abdominal situs inversus	DNAH5 DNAH11	9.46e-04	9	73	2	MP:0011249
MousePheno	atrioventricular septal defect	DNAAF4 PKD2 DNAH5 DNAH11	9.63e-04	84	73	4	MP:0010412
MousePheno	domed cranium	DNAAF4 CSF1R DNAH5 CDON	1.01e-03	85	73	4	MP:0000440
MousePheno	abnormal atrioventricular septum morphology	DNAAF4 PKD2 DNAH5 DNAH11	1.10e-03	87	73	4	MP:0010592
MousePheno	abnormal tail morphology	SALL4 BRWD3 PTK7 JAK1 NDC1 CSF1R MTHFD1 KMT2A	1.16e-03	403	73	8	MP:0002111
MousePheno	ear inflammation	SALL4 JAK1 DNAH5	1.18e-03	40	73	3	MP:0001849
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH5 DNAH11	4.46e-05	14	95	3	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH5 DNAH11	4.46e-05	14	95	3	IPR013602
Domain	DHC_N2	DNAH12 DNAH5 DNAH11	4.46e-05	14	95	3	PF08393
Domain	AAA_8	DNAH12 DNAH5 DNAH11	4.46e-05	14	95	3	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH5 DNAH11	4.46e-05	14	95	3	IPR011704
Domain	AAA_5	DNAH12 DNAH5 DNAH11	4.46e-05	14	95	3	PF07728
Domain	DHC_fam	DNAH12 DNAH5 DNAH11	5.55e-05	15	95	3	IPR026983
Domain	Dynein_heavy_dom	DNAH12 DNAH5 DNAH11	5.55e-05	15	95	3	IPR004273
Domain	Dynein_heavy	DNAH12 DNAH5 DNAH11	5.55e-05	15	95	3	PF03028
Domain	HEAT	CLASP1 XPO1 ECPAS PIK3R4	2.16e-04	58	95	4	IPR000357
Domain	HEAT_REPEAT	CLASP1 XPO1 ECPAS PIK3R4	4.45e-04	70	95	4	PS50077
Domain	DHC_N1	DNAH5 DNAH11	7.03e-04	8	95	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH5 DNAH11	7.03e-04	8	95	2	IPR013594
Domain	-	BRWD3 PIK3R4 NBAS WDR97 TULP4 PAN2 CDC20	1.55e-03	333	95	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	BRWD3 PIK3R4 NBAS WDR97 TULP4 PAN2 CDC20	1.61e-03	335	95	7	IPR015943
Domain	COS_domain	MID2 MID1	1.63e-03	12	95	2	IPR017903
Domain	COS	MID2 MID1	1.63e-03	12	95	2	PS51262
Domain	MATH/TRAF_dom	SPOPL SPOP	1.63e-03	12	95	2	IPR002083
Domain	MATH	SPOPL SPOP	1.63e-03	12	95	2	PS50144
Domain	MATH	SPOPL SPOP	1.63e-03	12	95	2	SM00061
Domain	MATH	SPOPL SPOP	1.63e-03	12	95	2	PF00917
Domain	HEAT	CLASP1 ECPAS PIK3R4	1.87e-03	48	95	3	PF02985
Domain	Dynein_HC_stalk	DNAH5 DNAH11	2.24e-03	14	95	2	IPR024743
Domain	MT	DNAH5 DNAH11	2.24e-03	14	95	2	PF12777
Domain	-	SPOPL SPOP	2.24e-03	14	95	2	2.60.210.10
Domain	Bbox_C	MID2 MID1	2.57e-03	15	95	2	IPR003649
Domain	BBC	MID2 MID1	2.57e-03	15	95	2	SM00502
Domain	WD_REPEATS_1	BRWD3 PIK3R4 NBAS WDR97 TULP4 CDC20	2.96e-03	278	95	6	PS00678
Domain	WD_REPEATS_2	BRWD3 PIK3R4 NBAS WDR97 TULP4 CDC20	3.02e-03	279	95	6	PS50082
Domain	WD_REPEATS_REGION	BRWD3 PIK3R4 NBAS WDR97 TULP4 CDC20	3.02e-03	279	95	6	PS50294
Domain	HEAT_type_2	CLASP1 PIK3R4	3.31e-03	17	95	2	IPR021133
Domain	WD40_repeat_dom	BRWD3 PIK3R4 WDR97 TULP4 PAN2 CDC20	4.09e-03	297	95	6	IPR017986
Domain	Myosin-like_IQ_dom	MYH11 IQGAP1	4.14e-03	19	95	2	IPR027401
Domain	-	MYH11 IQGAP1	4.14e-03	19	95	2	4.10.270.10
Domain	-	SACS TOP2A	4.58e-03	20	95	2	3.30.565.10
Domain	Homeobox_Antennapedia_CS	HOXC6 HOXD4	5.05e-03	21	95	2	IPR001827
Domain	HATPase_C	SACS TOP2A	5.05e-03	21	95	2	IPR003594
Domain	-	DNAJC13 CLASP1 XPO1 ECPAS PIK3R4	5.53e-03	222	95	5	1.25.10.10
Domain	Quino_amine_DH_bsu	BRWD3 NBAS	5.53e-03	22	95	2	IPR011044
Pubmed	Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development.	PTK7 PKD2 DNAH11	8.40e-08	4	97	3	19235720
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH11 DNAJC13 CDC42BPA SALL4 XPO1 ECPAS IQGAP1 NBAS	1.05e-07	202	97	8	33005030
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH12 DNAH5 DNAH11	7.30e-07	7	97	3	9256245
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A MYH11 DNAJC13 CLASP1 VPS45 GRIA1 XPO1 DDX1 ADD3 IQGAP1 PIK3R4 SACS MTHFD1 KMT2A PYGB DNAH11	2.12e-06	1431	97	16	37142655
Pubmed	Defining the membrane proteome of NK cells.	DNAJC13 CLASP1 NCSTN XPO1 ECPAS ANKRD27 DDX1 PIK3R4 NBAS NDC1 UBR5 MTHFD1 PYGB DDX20	4.48e-06	1168	97	14	19946888
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH12 DNAH5 DNAH11	7.49e-06	14	97	3	9373155
Pubmed	Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.	KMT2A TOP2A	7.70e-06	2	97	2	31202576
Pubmed	Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway.	STAT3 JAK1	7.70e-06	2	97	2	26937622
Pubmed	Unique genome-wide map of TCF4 and STAT3 targets using ChIP-seq reveals their association with new molecular subtypes of glioblastoma.	TCF7L2 STAT3	7.70e-06	2	97	2	23295773
Pubmed	[Study on correlation of JAK/STAT signal pathway with progression and prognosis in hepatocellular carcinoma].	STAT3 JAK1	7.70e-06	2	97	2	20368117
Pubmed	JAK/STAT signal pathway activation promotes progression and survival of human oesophageal squamous cell carcinoma.	STAT3 JAK1	7.70e-06	2	97	2	22301404
Pubmed	Inhibition of JAK1/STAT3 signaling mediates compound K-induced apoptosis in human multiple myeloma U266 cells.	STAT3 JAK1	7.70e-06	2	97	2	21420464
Pubmed	Nuclear retention of STAT3 through the coiled-coil domain regulates its activity.	XPO1 STAT3	7.70e-06	2	97	2	16140268
Pubmed	Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast implant-associated anaplastic large cell lymphoma anaplastic large cell lymphoma.	STAT3 JAK1	7.70e-06	2	97	2	27198716
Pubmed	Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.	DNAH5 DNAH11	7.70e-06	2	97	2	32357925
Pubmed	Activation of JAK/STAT signalling in neurons following spinal cord injury in mice.	STAT3 JAK1	7.70e-06	2	97	2	16417589
Pubmed	Caffeic Acid Inhibits Chronic UVB-Induced Cellular Proliferation Through JAK-STAT3 Signaling in Mouse Skin.	STAT3 JAK1	7.70e-06	2	97	2	27029485
Pubmed	XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer.	XPO1 STAT3	7.70e-06	2	97	2	24431073
Pubmed	Nucleocytoplasmic shuttling of persistently activated STAT3.	XPO1 STAT3	7.70e-06	2	97	2	17726064
Pubmed	Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells.	STAT3 JAK1	7.70e-06	2	97	2	25065853
Pubmed	Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.	STAT3 JAK1	7.70e-06	2	97	2	18320073
Pubmed	[Regulatory effect of resveratrol on JAK1/STAT3 signal transduction pathway in leukemia].	STAT3 JAK1	7.70e-06	2	97	2	18718058
Pubmed	JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling.	STAT3 JAK1	7.70e-06	2	97	2	21216930
Pubmed	Dual JAK1 and STAT3 mutations in a breast implant-associated anaplastic large cell lymphoma.	STAT3 JAK1	7.70e-06	2	97	2	29637270
Pubmed	A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.	SPOPL SPOP	7.70e-06	2	97	2	16740475
Pubmed	Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively.	STAT3 JAK1	7.70e-06	2	97	2	31819176
Pubmed	Jak1/Stat3 Activation Alters Phosphate Metabolism Independently of Sex and Extracellular Phosphate Levels.	STAT3 JAK1	7.70e-06	2	97	2	34515136
Pubmed	Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome.	MID2 MID1	7.70e-06	2	97	2	26788540
Pubmed	Evolutionary expansion of SPOP and associated TD/POZ gene family: impact of evolutionary route on gene expression pattern.	SPOPL SPOP	7.70e-06	2	97	2	20399258
Pubmed	Inside-out and outside-in organotypic normal human skin culture: JAK-STAT pathway is activated after pro-inflammatory psoriatic cytokine exposure.	STAT3 JAK1	7.70e-06	2	97	2	34781228
Pubmed	[Effect of Janus kinase inhibitor AG490 on invasion and metastasis of human breast cancer cells].	STAT3 JAK1	7.70e-06	2	97	2	18390202
Pubmed	Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling.	STAT3 JAK1	7.70e-06	2	97	2	34314383
Pubmed	Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3.	STAT3 JAK1	7.70e-06	2	97	2	18413761
Pubmed	Ciliary defects and genetics of primary ciliary dyskinesia.	DNAH5 DNAH11	7.70e-06	2	97	2	19410201
Pubmed	A novel function of granulocyte colony-stimulating factor in mobilization of human hematopoietic progenitor cells.	STAT3 JAK1	7.70e-06	2	97	2	19255588
Pubmed	Low-dose radiation decreases tumor progression via the inhibition of the JAK1/STAT3 signaling axis in breast cancer cell lines.	STAT3 JAK1	7.70e-06	2	97	2	28240233
Pubmed	Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4.	SALL4 STAT3	7.70e-06	2	97	2	19151334
Pubmed	JAK1/STAT3 regulatory effect of β-caryophyllene on MG-63 osteosarcoma cells via ROS-induced apoptotic mitochondrial pathway by DNA fragmentation.	STAT3 JAK1	7.70e-06	2	97	2	32359221
Pubmed	Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.	SPOPL SPOP	7.70e-06	2	97	2	16651542
Pubmed	[Astaxanthin inhibits proliferation and promotes apoptosis of A549 lung cancer cells via blocking JAK1/STAT3 pathway].	STAT3 JAK1	7.70e-06	2	97	2	27371847
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CLASP1 XPO1 ECPAS PIK3R4 DNAH12 MTHFD1 KMT2A PLCB4 DNAI7	1.09e-05	497	97	9	36774506
Pubmed	Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing.	TCF7L2 DDX1 TOP2A	1.15e-05	16	97	3	16230076
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	DNAJC13 XPO1 ECPAS DDX1 STAT3 ADD3 IQGAP1 MTHFD1 CSTF3 DDX20	1.21e-05	638	97	10	33239621
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	DNAJC13 CDC42BPA VPS45 ANKRD27 PIK3R4 NBAS NDC1 VPS13A TMEM131L	1.21e-05	504	97	9	34432599
Pubmed	Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1.	HOXC6 HOXD4 KMT2A	1.97e-05	19	97	3	15741318
Pubmed	Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.	STAT3 JAK1	2.31e-05	3	97	2	28356514
Pubmed	Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity.	XPO1 STAT3	2.31e-05	3	97	2	20826784
Pubmed	Particular Role of JAK/STAT3 Signaling in Functional Control of Mesenchymal Progenitor Cells.	STAT3 JAK1	2.31e-05	3	97	2	29308566
Pubmed	Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.	TCF7L2 TOP2A	2.31e-05	3	97	2	26947016
Pubmed	Overexpression of RPN2 promotes osteogenic differentiation of hBMSCs through the JAK/STAT3 pathway.	STAT3 JAK1	2.31e-05	3	97	2	31743606
Pubmed	The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitination.	STAT3 JAK1	2.31e-05	3	97	2	23185365
Pubmed	Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta.	XPO1 TOP2A	2.31e-05	3	97	2	12821127
Pubmed	Fer is a downstream effector of insulin and mediates the activation of signal transducer and activator of transcription 3 in myogenic cells.	STAT3 JAK1	2.31e-05	3	97	2	12738762
Pubmed	MicroRNA-340 inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting JAK1.	STAT3 JAK1	2.31e-05	3	97	2	27998770
Pubmed	The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling.	STAT3 JAK1	2.31e-05	3	97	2	26215634
Pubmed	JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non-Small Cell Lung Cancer.	STAT3 JAK1	2.31e-05	3	97	2	28729401
Pubmed	Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.	STAT3 JAK1	2.31e-05	3	97	2	8272872
Pubmed	Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.	STAT3 JAK1	2.31e-05	3	97	2	8272873
Pubmed	A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis.	SALL4 KMT2A	2.31e-05	3	97	2	24051379
Pubmed	INCB16562, a JAK1/2 selective inhibitor, is efficacious against multiple myeloma cells and reverses the protective effects of cytokine and stromal cell support.	STAT3 JAK1	2.31e-05	3	97	2	20072651
Pubmed	Oxidative stress-induced IL-15 trans-presentation in keratinocytes contributes to CD8+ T cells activation via JAK-STAT pathway in vitiligo.	STAT3 JAK1	2.31e-05	3	97	2	31078730
Pubmed	Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways.	STAT3 JAK1	2.31e-05	3	97	2	11751884
Pubmed	Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells.	STAT3 JAK1	2.31e-05	3	97	2	15923602
Pubmed	Piperlongumine inhibits gastric cancer cells via suppression of the JAK1,2/STAT3 signaling pathway.	STAT3 JAK1	2.31e-05	3	97	2	27053336
Pubmed	Genomic characterization of HIV-associated plasmablastic lymphoma identifies pervasive mutations in the JAK-STAT pathway.	STAT3 JAK1	2.31e-05	3	97	2	33225311
Pubmed	PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.	STAT3 JAK1	2.31e-05	3	97	2	25113558
Pubmed	IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes.	STAT3 JAK1	2.31e-05	3	97	2	7543512
Pubmed	A novel viral SOCS from infectious spleen and kidney necrosis virus: interacts with Jak1 and inhibits IFN-α induced Stat1/3 activation.	STAT3 JAK1	2.31e-05	3	97	2	22844427
Pubmed	Mutations leading to constitutive active gp130/JAK1/STAT3 pathway.	STAT3 JAK1	2.31e-05	3	97	2	26188635
Pubmed	Polymorphisms in JAK/STAT signaling pathway genes and risk of non-Hodgkin lymphoma.	STAT3 JAK1	2.31e-05	3	97	2	23768868
Pubmed	Jak1-STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis.	STAT3 JAK1	2.31e-05	3	97	2	27440725
Pubmed	Constitutive activation of signal transducer and activator of transcription 3 regulates expression of vascular endothelial growth factor in human meningioma differentiation.	STAT3 JAK1	2.31e-05	3	97	2	20052595
Pubmed	Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation.	STAT3 JAK1	2.31e-05	3	97	2	19056487
Pubmed	CD146+CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.	STAT3 JAK1	2.31e-05	3	97	2	38459564
Pubmed	Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network.	SALL4 PTK7	2.31e-05	3	97	2	17908931
Pubmed	Bimodal degradation of MLL by SCFSkp2 and APCCdc20 assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions.	KMT2A CDC20	2.31e-05	3	97	2	17908926
Pubmed	JAK1-STAT1-STAT3, a key pathway promoting proliferation and preventing premature differentiation of myoblasts.	STAT3 JAK1	2.31e-05	3	97	2	17908914
Pubmed	SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.	SPOP TOP2A	2.31e-05	3	97	2	31967940
Pubmed	MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.	MID2 MID1	2.31e-05	3	97	2	11806752
Pubmed	Interleukin-6 promotes proliferative vitreoretinopathy by inducing epithelial-mesenchymal transition via the JAK1/STAT3 signaling pathway.	STAT3 JAK1	2.31e-05	3	97	2	32818015
Pubmed	Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons.	STAT3 JAK1	2.31e-05	3	97	2	24152426
Pubmed	Aloin suppresses lipopolysaccharide‑induced inflammation by inhibiting JAK1‑STAT1/3 activation and ROS production in RAW264.7 cells.	STAT3 JAK1	2.31e-05	3	97	2	30066904
Pubmed	Zinc regulates the acute phase response and serum amyloid A production in response to sepsis through JAK-STAT3 signaling.	STAT3 JAK1	2.31e-05	3	97	2	24732911
Pubmed	METTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway.	STAT3 JAK1	2.31e-05	3	97	2	38001065
Pubmed	MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.	STAT3 JAK1	2.31e-05	3	97	2	21325207
Pubmed	15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells.	STAT3 JAK1	2.31e-05	3	97	2	16737695
Pubmed	Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left-right axis formation.	PKD2 DNAH11	2.31e-05	3	97	2	23357539
Pubmed	Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway.	STAT3 JAK1	2.31e-05	3	97	2	28154170
Pubmed	Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma.	DDX1 NBAS	2.31e-05	3	97	2	17028906
Pubmed	Stat3 activation by Src induces specific gene regulation and is required for cell transformation.	STAT3 JAK1	2.31e-05	3	97	2	9566874
Pubmed	Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population.	STAT3 JAK1	2.31e-05	3	97	2	27049718
Pubmed	Targeting the IL-6/JAK/STAT3 signalling axis in cancer.	STAT3 JAK1	2.31e-05	3	97	2	29405201
Pubmed	JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter.	STAT3 JAK1	2.31e-05	3	97	2	25931145
Pubmed	Amorfrutin A inhibits TNF-α induced JAK/STAT signaling, cell survival and proliferation of human cancer cells.	STAT3 JAK1	2.31e-05	3	97	2	28879797
Pubmed	Surfactant protein C dampens inflammation by decreasing JAK/STAT activation during lung repair.	STAT3 JAK1	2.31e-05	3	97	2	29345196
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	ABCA13 XPO1 MID1 VPS13A KMT2A DNAH5	2.68e-05	208	97	6	33230847
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDC42BPA CLASP1 ANKRD27 DDX1 STAT3 PIK3R4 N4BP2 KMT2A MAPK4 CDC20 MTSS2	2.88e-05	861	97	11	36931259
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TCF7L2 VPS45 XPO1 ECPAS DDX1 STAT3 IQGAP1 NBAS NDC1 UBR5 KMT2A DDX20 CDC20 TOP2A	4.59e-05	1440	97	14	30833792
Pubmed	Forward spreading in the establishment of a vertebrate Hox expression boundary: the expression domain separates into anterior and posterior zones, and the spread occurs across implanted glass barriers.	HOXC6 HOXD4	4.60e-05	4	97	2	7912569
Pubmed	Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway.	STAT3 JAK1	4.60e-05	4	97	2	18451094
Interaction	LRRC31 interactions	MYH11 DNAJC13 CDC42BPA SALL4 XPO1 ECPAS IQGAP1 NBAS	4.86e-06	205	93	8	int:LRRC31
Cytoband	2p24	DDX1 NBAS	2.88e-04	12	97	2	2p24
GeneFamily	Dyneins, axonemal	DNAH12 DNAH5 DNAH11	3.79e-05	17	71	3	536
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DNAJC13 TCF7L2 CDC42BPA CLASP1 XPO1 PIK3R4 NBAS MTAP SACS UBR5 MID1 VPS13A PKD2 TMEM131L PLCB4 SPOP TOP2A	6.63e-09	856	92	17	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	DNAJC13 TCF7L2 CDC42BPA CLASP1 XPO1 UBR5 MID1 VPS13A PKD2 SPOP TOP2A	7.35e-07	466	92	11	M13522
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	CLASP1 XPO1 PIK3R4 SACS UBR5 VPS13A TMEM131L SPOP TOP2A	1.13e-06	300	92	9	M8702
Coexpression	HALLMARK_UV_RESPONSE_DN	CACNA1A CDC42BPA ADD3 PLCB4 SPOP CDON	1.20e-05	144	92	6	M5942
Coexpression	GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP	CLASP1 ADD3 PCNX2 PIGC PAN2 KMT2A	7.36e-05	199	92	6	M7596
Coexpression	GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN	CLASP1 ADD3 PCNX2 PIGC PAN2 MPPE1	7.36e-05	199	92	6	M7607
Coexpression	HALLMARK_MITOTIC_SPINDLE	CDC42BPA CLASP1 MID1 PKD2 TUBD1 TOP2A	7.36e-05	199	92	6	M5893
Coexpression	GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP	CDC42BPA MID2 ADD3 PCNX2 PAN2 TMEM131L	7.36e-05	199	92	6	M8298
Coexpression	GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_UP	VPS45 ECPAS RASSF6 TMEM131L ZNF518B TUBD1	7.57e-05	200	92	6	M8959
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	MYH11 DNAJC13 TCF7L2 CLASP1 ASPN STAT3 ADD3 JAK1 HOXC6 CSF1R MID1 PKD2 TOP2A CDON	1.09e-05	799	94	14	gudmap_developingGonad_e18.5_epididymis_1000
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.03e-08	193	97	8	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.12e-08	195	97	8	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.12e-08	195	97	8	d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ABCA13 DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.12e-08	195	97	8	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.12e-08	195	97	8	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.12e-08	195	97	8	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	ABCA13 DNAH12 CFAP221 PLCB4 DNAH5 TOP2A CFAP46 DNAH11	1.17e-08	196	97	8	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	ABCA13 DNAH12 CFAP221 PLCB4 DNAH5 TOP2A CFAP46 DNAH11	1.17e-08	196	97	8	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABHD12B ABCA13 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	1.38e-07	180	97	7	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.73e-07	186	97	7	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	Multiciliated\|World / shred by cell class for nasal brushing	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.93e-07	189	97	7	34b110aef839376228c5a403a6b5047a945f472b
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	1.93e-07	189	97	7	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.00e-07	190	97	7	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.00e-07	190	97	7	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.07e-07	191	97	7	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.07e-07	191	97	7	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABHD12B ABCA13 DNAAF4 DNAH12 DNAI7 CDC20 CFAP46	2.07e-07	191	97	7	683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.07e-07	191	97	7	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.07e-07	191	97	7	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.07e-07	191	97	7	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.07e-07	191	97	7	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.07e-07	191	97	7	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.15e-07	192	97	7	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	multiciliated\|World / shred by cell class for turbinate	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.15e-07	192	97	7	0f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.15e-07	192	97	7	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.22e-07	193	97	7	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.30e-07	194	97	7	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.30e-07	194	97	7	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.30e-07	194	97	7	958e648138676d46698090b4046cb484083ae449
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.30e-07	194	97	7	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAAF4 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	2.30e-07	194	97	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.30e-07	194	97	7	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH12 CFAP221 PLCB4 DNAI7 DNAH5 CFAP46 DNAH11	2.38e-07	195	97	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH12 CFAP221 PLCB4 DNAI7 DNAH5 CFAP46 DNAH11	2.38e-07	195	97	7	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH12 CFAP221 PLCB4 DNAI7 DNAH5 CFAP46 DNAH11	2.38e-07	195	97	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.38e-07	195	97	7	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.38e-07	195	97	7	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAAF4 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	2.38e-07	195	97	7	6365e3893e38231090ec2dbef010dec71dea3d07
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.38e-07	195	97	7	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.47e-07	196	97	7	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.47e-07	196	97	7	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.47e-07	196	97	7	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.55e-07	197	97	7	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.55e-07	197	97	7	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.55e-07	197	97	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.55e-07	197	97	7	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH12 DNAI7 CDC20 DNAH5 TOP2A CFAP46 DNAH11	2.55e-07	197	97	7	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.55e-07	197	97	7	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH12 CFAP221 DNAI7 CDC20 TOP2A CFAP46 DNAH11	2.64e-07	198	97	7	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.64e-07	198	97	7	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	1ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	1df69c0cb5f759f6a2152521842506a75bb95cae
ToppCell	Mild-Epithelial-Epithelial-\|Mild / Condition, Lineage, Cell class and cell subclass	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	81115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	74087b4b5e567310fc4ac58fb267ff651a180680
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	00b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCell	Mild-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell	Mild-Epithelial-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	91308b255783ad4029e5575028c18d7550832c51
ToppCell	distal-Epithelial-Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	6ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCell	Mild_COVID-19-Epithelial\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.73e-07	199	97	7	72689bda7476930887ae007682fcab27f956f050
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CWH43 DNAAF4 DNAH12 CFAP221 DNAH5 CFAP46 DNAH11	2.83e-07	200	97	7	cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CWH43 DNAAF4 DNAH12 CFAP221 DNAH5 CFAP46 DNAH11	2.83e-07	200	97	7	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CWH43 DNAAF4 DNAH12 CFAP221 DNAH5 CFAP46 DNAH11	2.83e-07	200	97	7	cf71c3f6281650940f3ade04ea62be3f340bfc68
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.83e-07	200	97	7	f1a49bc818054fb0734d3b84725ee6487b034567
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Ciliated\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.83e-07	200	97	7	d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CWH43 DNAAF4 DNAH12 CFAP221 DNAH5 CFAP46 DNAH11	2.83e-07	200	97	7	873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	2.83e-07	200	97	7	cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	ABCA13 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	9.94e-07	151	97	6	8216462e723fec2797387929dde095370947e10a
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ABCA13 ESYT3 DNAH12 CFAP221 CFAP46 DNAH11	1.20e-06	156	97	6	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAH12 CFAP221 DNAH5 CFAP46 DNAH11	1.91e-06	169	97	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Deuterosomal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAAF4 DNAH12 CFAP221 DNAI7 CDC20 CFAP46	2.05e-06	171	97	6	52aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAH12 CFAP221 DNAH5 CFAP46 DNAH11	2.42e-06	176	97	6	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAH12 WDR97 GALNT8 CFAP46 DNAH11	2.58e-06	178	97	6	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	15-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	DNAAF4 DNAH12 CFAP221 DNAI7 DNAH5 DNAH11	2.58e-06	178	97	6	d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 WDR97 CFAP221 DNAH5 CFAP46 DNAH11	2.67e-06	179	97	6	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	ABCA13 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	2.94e-06	182	97	6	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	21-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	ABHD12B DNAAF4 DNAH12 CFAP221 DNAI7 CFAP46	2.94e-06	182	97	6	6e35892fa959ee31591850ded8f1088195ddeb01
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1A ECPAS VPS13A TMEM131L CDC20 TOP2A	3.13e-06	184	97	6	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1A ECPAS VPS13A TMEM131L CDC20 TOP2A	3.13e-06	184	97	6	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	CACNA1A ECPAS VPS13A TMEM131L CDC20 TOP2A	3.13e-06	184	97	6	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SALL4 DCX PTPRQ DNAH5 DNAH11	3.13e-06	184	97	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CACNA1A ECPAS VPS13A TMEM131L CDC20 TOP2A	3.13e-06	184	97	6	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1A ECPAS VPS13A TMEM131L CDC20 TOP2A	3.13e-06	184	97	6	d31d4116d1d196633784863781fa45673607a421
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SALL4 DCX PTPRQ DNAH5 DNAH11	3.13e-06	184	97	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SALL4 DCX PTPRQ DNAH5 DNAH11	3.13e-06	184	97	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	CACNA1A ECPAS VPS13A TMEM131L CDC20 TOP2A	3.13e-06	184	97	6	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	CACNA1A ECPAS VPS13A TMEM131L CDC20 TOP2A	3.13e-06	184	97	6	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH12 CFAP221 DNAI7 DNAH5 CFAP46 DNAH11	3.23e-06	185	97	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	ABCA13 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	3.23e-06	185	97	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAAF4 DNAH12 CFAP221 DNAI7 CFAP46 DNAH11	3.33e-06	186	97	6	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 CFAP46	3.43e-06	187	97	6	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA13 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	3.65e-06	189	97	6	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	ABCA13 DNAH12 CFAP221 DNAH5 CFAP46 DNAH11	3.65e-06	189	97	6	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABHD12B ABCA13 DNAAF4 DNAH12 DNAI7 DNAH5	3.65e-06	189	97	6	b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	ABCA13 DNAH12 DNAI7 DNAH5 CFAP46 DNAH11	3.65e-06	189	97	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABHD12B DNAAF4 DNAH12 DNAI7 CDC20 CFAP46	3.76e-06	190	97	6	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	cellseq2-Epithelial-Epithelial_Airway\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA13 DNAH12 CFAP221 DNAI7 CFAP46 DNAH11	3.76e-06	190	97	6	17829f4de31b3d9e4d71ba4817d18842aa699773
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABHD12B DNAAF4 DNAH12 DNAI7 CDC20 CFAP46	3.76e-06	190	97	6	05455775845f4ded5c27e7b83242078d23162aaf
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 DNAH11	3.88e-06	191	97	6	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 DNAH11	3.88e-06	191	97	6	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 DNAH12 CFAP221 DNAI7 DNAH5 DNAH11	3.88e-06	191	97	6	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 XPO1 UBR5	5.07e-06	11	94	3	DOID:3717 (is_implicated_in)
Disease	Primary Ciliary Dyskinesia	DNAAF4 CFAP221 DNAH5 DNAH11	1.55e-05	47	94	4	C4551720
Disease	Kartagener syndrome (is_implicated_in)	DNAH5 DNAH11	6.00e-05	4	94	2	DOID:0050144 (is_implicated_in)
Disease	Coronary heart disease	PLA2G7 TCF7L2 DNAH11	6.04e-05	24	94	3	C0010068
Disease	colon adenocarcinoma (is_implicated_in)	STAT3 CSF1R UBR5	7.72e-05	26	94	3	DOID:234 (is_implicated_in)
Disease	stomach cancer (is_marker_for)	XPO1 STAT3 CSF1R UBR5 SPOP	9.36e-05	142	94	5	DOID:10534 (is_marker_for)
Disease	Acute myelomonocytic leukemia	MYH11 KMT2A	9.98e-05	5	94	2	C0023479
Disease	response to bevacizumab, Proteinuria	JAK1 DNAH5	9.98e-05	5	94	2	EFO_0005943, HP_0000093
Disease	uric acid measurement	DNAJC13 TCF7L2 CDC42BPA VPS45 DDX1 NDC1 PKD2 PYGB ZNF518B	1.45e-04	610	94	9	EFO_0004761
Disease	Opitz GBBB syndrome (implicated_via_orthology)	MID2 MID1	1.49e-04	6	94	2	DOID:0080697 (implicated_via_orthology)
Disease	Primary ciliary dyskinesia	DNAAF4 DNAH5 DNAH11	2.07e-04	36	94	3	cv:C0008780
Disease	Leukemia, Myelocytic, Acute	MYH11 STAT3 JAK1 CSF1R KMT2A	2.35e-04	173	94	5	C0023467
Disease	cerebellar ataxia (implicated_via_orthology)	CACNA1A VPS13A	2.78e-04	8	94	2	DOID:0050753 (implicated_via_orthology)
Disease	cervix uteri carcinoma in situ (is_marker_for)	STAT3 CSF1R TOP2A	3.28e-04	42	94	3	DOID:8991 (is_marker_for)
Disease	Nephroblastoma	DDX1 NBAS	4.44e-04	10	94	2	Orphanet_654
Disease	non-high density lipoprotein cholesterol measurement	CACNA1A DNAJC13 STAT3 NDC1 CSF1R PIGC RASSF6 PYGB DNAH11	4.57e-04	713	94	9	EFO_0005689
Disease	chronic kidney disease, Proteinuria	CACNA1A KMT2A	5.42e-04	11	94	2	EFO_0003884, HP_0000093
Disease	sitting height ratio	TCF7L2 JAK1 PKD2	5.84e-04	51	94	3	EFO_0007118
Disease	total blood protein measurement	DNAJC13 TCF7L2 XPO1 MTAP CSF1R TMEM131L TUBD1	5.91e-04	449	94	7	EFO_0004536
Disease	colorectal cancer (is_implicated_in)	TCF7L2 XPO1 JAK1 SPOP	6.17e-04	121	94	4	DOID:9256 (is_implicated_in)
Disease	acute myeloid leukemia (implicated_via_orthology)	KMT2A TOP2A	6.49e-04	12	94	2	DOID:9119 (implicated_via_orthology)
Disease	Acute Myeloid Leukemia, M1	MYH11 STAT3 CSF1R KMT2A	6.97e-04	125	94	4	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	MYH11 STAT3 CSF1R KMT2A	6.97e-04	125	94	4	C1879321
Disease	leukemia	STAT3 KMT2A TOP2A	7.28e-04	55	94	3	C0023418
Disease	Prostatic Neoplasms	CLDN7 XPO1 STAT3 JAK1 MTAP KMT2A SPOP TOP2A	7.95e-04	616	94	8	C0033578
Disease	Malignant neoplasm of prostate	CLDN7 XPO1 STAT3 JAK1 MTAP KMT2A SPOP TOP2A	7.95e-04	616	94	8	C0376358
Disease	Bipolar Disorder	CACNA1A TCF7L2 ABCA13 GRIA1 ADD3 MTHFD1 MPPE1	8.43e-04	477	94	7	C0005586
Disease	Kartagener syndrome (implicated_via_orthology)	DNAH5 DNAH11	8.91e-04	14	94	2	DOID:0050144 (implicated_via_orthology)
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	JAK1 HOXD4 KMT2A	9.86e-04	61	94	3	C1961102
Disease	hepatoblastoma (is_marker_for)	SALL4 SPOP	1.03e-03	15	94	2	DOID:687 (is_marker_for)
Disease	Lung diseases	STAT3 DNAH5 DNAH11	2.00e-03	78	94	3	C0024115
Disease	lung non-small cell carcinoma (is_marker_for)	STAT3 CSF1R UBR5 SPOP	2.12e-03	169	94	4	DOID:3908 (is_marker_for)
Disease	type 2 diabetes mellitus (is_implicated_in)	PLA2G7 PCSK2 TCF7L2 STAT3	2.21e-03	171	94	4	DOID:9352 (is_implicated_in)
Disease	otitis media (implicated_via_orthology)	SALL4 DNAH5	2.23e-03	22	94	2	DOID:10754 (implicated_via_orthology)
Disease	Bronchiectasis	DNAH5 DNAH11	2.23e-03	22	94	2	C0006267
Disease	lung adenocarcinoma (is_marker_for)	XPO1 CSF1R SPOP	2.56e-03	85	94	3	DOID:3910 (is_marker_for)
Disease	hepatocellular carcinoma (is_implicated_in)	XPO1 JAK1 CSF1R SPOP	2.72e-03	181	94	4	DOID:684 (is_implicated_in)
Disease	unipolar depression, schizophrenia	TCF7L2 VPS45	2.87e-03	25	94	2	EFO_0003761, MONDO_0005090
Disease	insomnia measurement	ZNF536 TCF7L2 GRIA1 UBR5 KMT2A DNAH11	2.97e-03	443	94	6	EFO_0007876
Disease	ergothioneine measurement	CACNA1A DNAH5	3.10e-03	26	94	2	EFO_0021163

Protein segments in the cluster

Peptide	Gene	Start	Entry
KQSFQYRMWQFVVSP	CACNA1A	1551	O00555
ANKIISQTWPYLSMI	ESYT3	121	A0FGR9
AQNQLVIWKYPTMAK	CDC20	421	Q12834
KQMNVAAAVWAVVSY	CPQ	446	Q9Y646
KTRWLNSPNTYMKVN	ADD3	436	Q9UEY8
FTNMWVASINYPLLK	ABHD12B	246	Q7Z5M8
YNNAIQALQKPEMEW	CFAP46	1201	Q8IYW2
TLNRTYVNMKQKPVW	DNAH11	2186	Q96DT5
SMQNIVWDPQKVQYD	ABCA13	261	Q86UQ4
YSVNLQKQPWNKMDL	BRWD3	966	Q6RI45
WLTNQGNYKLLVTME	ANGPTL2	356	Q9UKU9
INWIYSSLPASKQML	DDX20	226	Q9UHI6
AISLFNNPVKYWEMQ	ASPN	346	Q9BXN1
PVDIYKSWVNQMESQ	IQGAP1	1091	P46940
TIMPSKVNYQANIWA	MTAP	66	Q13126
MAHQYPSWIFINEKT	RASSF6	36	Q6ZTQ3
VATKKAQEWQPVYPM	JAK1	556	P23458
LSDYNVWSMLKPINT	NCSTN	251	Q92542
VKTEIPNWMANLSYI	ANKRD27	321	Q96NW4
TYASKIVQWLAQRMN	OVOS1	1001	Q6IE37
WTYDSVKTPIQRAMQ	FAM47C	1006	Q5HY64
AVQFDMNWKVPAILY	PAN2	906	Q504Q3
GWFTMNNLLPNAVYK	KIAA0100	1956	Q14667
TWCQETYSQTKPKMQ	APOO	76	Q9BUR5
TYSQTKPKMQSLVQW	APOO	81	Q9BUR5
LSPNNYTKAIDMWAA	MAPK4	201	P31152
SVLNKWQMNPYDRGS	DDX1	86	Q92499
IDWNNPAIINKMYKV	ECPAS	291	Q5VYK3
WKGINFVMVNSVALN	MPPE1	186	Q53F39
KLQFVLTYVAPWQMA	PCNX2	1286	A6NKB5
PIIYSVKNKQIQWGM	OR51Q1	291	Q8NH59
PLSYTTIMNWQVCTV	OR4X2	121	Q8NGF9
QAIVNDMKSSYPIWE	MTSS2	16	Q765P7
NTPQEAQQVDMWKKY	CSTF3	241	Q12996
QTRNAEEKIMNTWYP	DNAH12	251	Q6ZR08
MQPYTKNWTQVTEFV	OR6Q1	1	Q8NGQ2
LGSYWNIISTVIQMQ	OR2D3	231	Q8NGH3
YASKIVQWLAQQMNS	OVOS2	1206	Q6IE36
QAWPPMKSEYVITNN	NBAS	2181	A2RRP1
NNVNVVYTPWSNLKK	CCDC25	86	Q86WR0
YINPVAHMKSSAWVN	PLA2G7	26	Q13093
YKDNIQMWSLHNIVP	ETAA1	231	Q9NY74
WMQTVYTQVRSKPDS	PTPRQ	141	Q9UMZ3
RYPNIMTWKVCVQLA	OR2D2	131	Q9H210
QKASIQIYPWMQRMN	HOXC6	116	P09630
WMKKVHVNSVNPNYT	HOXD4	136	P09016
QMFPNLATAANYWAK	EBLN1	296	P0CF75
APKNIYSIMQACWAL	CSF1R	881	P07333
SYNSVWVACQQMPQI	CCNDBP1	151	O95273
KHMVYLAWNIPLQNS	GALNT8	441	Q9NY28
TQIMLKWTYIPSSNN	CDON	841	Q4KMG0
WSVNVKTSANMKAPQ	DCX	146	O43602
TLIQDAHINMPYQSW	DNAI7	491	Q6TDU7
KMLNSNTESPYLIWN	DNAJC13	1631	O75165
MPLQVSDYSWQQTKT	DNAAF4	1	Q8WXU2
NLQWMPSKAYLQKQA	KMT2A	1196	Q03164
VNYTDTIPAKIMQQW	GRIA1	256	P42261
SVNVDPVVWNQYTSM	SALL4	961	Q9UJQ4
LWNEFLVMNVVPKAY	SACS	491	Q9NZJ4
GKWMIQYNNLNLKTP	MTHFD1	301	P11586
NMPFKAQIQKWVQYL	DNAH5	1601	Q8TE73
AITLWQMTTKQAPYS	MOS	266	P00540
TPFQYGTAQIKMQLW	CFAP221	226	Q4G0U5
GTAQIKMQLWISQFN	CFAP221	231	Q4G0U5
KMQLWISQFNSQPYE	CFAP221	236	Q4G0U5
TSLNPIWSYQMSNKV	CWH43	141	Q9H720
FTYMVAENPEVTKQW	PLCB4	111	Q15147
SRMIKYFVVQNPSSW	TMEM131L	601	A2VDJ0
MYAQPVTNTKEVKWQ	PIGC	1	Q92535
IQVPYNVQWMAIFSE	CDC42BPA	1356	Q5VT25
LVACTAIPQWQMSSY	CLDN7	21	O95471
LKIMDQAANPQYVWD	CLASP1	116	Q7Z460
YNASAWLTKNMDPLN	MYH11	586	P35749
SMHPLYQSWVIAAVQ	PIK3R4	1191	Q99570
QYSNSLKMNQIIWPY	TUBD1	161	Q9UJT1
QGFVYVMANKQPLWN	TULP4	1461	Q9NRJ4
KYMLLPNQVWDSIIQ	XPO1	656	O14980
VKPWQLLENMYNLTF	TAS1R3	421	Q7RTX0
NLSMQTTDQYWVPCL	VPS13A	181	Q96RL7
KTVTLQNYWNMVSLG	ZNF287	196	Q9HBT7
WTVNFGIVVNKPYMT	TMPRSS11B	236	Q86T26
QVKVVKFSYMWTINN	SPOPL	26	Q6IQ16
QIKVVKFSYMWTINN	SPOP	26	O43791
SILWYNMLTNNPKNV	STAT3	476	P40763
YVPNSAVLQQMWLNA	WDR97	1046	A6NE52
SWMIVPNIKQNHYTV	MID1	436	O15344
QIAVQYLQMKWPLLD	TCF7L2	146	Q9NQB0
VPGYKNNTVNTMRLW	PYGB	231	P11216
TIPDWLQAIQNYMKT	VASH2	106	Q86V25
DAITPLLNQWTYQAM	VPS45	221	Q9NRW7
SLLDGLYWKMQPSNQ	PKD2	286	Q13563
LYWKMQPSNQTEADN	PKD2	291	Q13563
KAAEMDPVNSYQAWQ	ZNF536	511	O15090
WTQTYKEQVLEPMLN	TOP2A	931	P11388
YNSVDSWMIVPNIKQ	MID2	481	Q9UJV3
SWMIVPNIKQNHYTV	MID2	486	Q9UJV3
QATPKPTVVWYRNQM	PTK7	436	Q13308
FQALIYWIKAMNQQT	UBR5	1951	O95071
YWIKAMNQQTTLDTP	UBR5	1956	O95071
NVKWVRSYDFIMPNS	ZNF518B	431	Q9C0D4
IMQNWYSLFTPVEAA	ZSWIM4	711	Q9H7M6
PSTNEWLQVASMNQK	KLHL42	276	Q9P2K6
TNLQAWEMKPYVALS	N4BP2	516	Q86UW6
TMRQPSVIYSWIQNK	NDC1	511	Q9BTX1
MNDPLFTKQWYLINT	PCSK2	121	P16519