Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionapolipoprotein binding

LRP1 LRP4

1.13e-0420162GO:0034185
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 LRP4 CCBE1 LTBP2 FBN1

2.27e-04749165GO:0005509
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 DKK1

4.38e-0439162GO:0070325
GeneOntologyMolecularFunctioncoreceptor activity

LRP1 LRP4

1.49e-0372162GO:0015026
GeneOntologyMolecularFunctionsulfur compound binding

LRP1 LTBP2 FBN1

2.01e-03323163GO:1901681
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

LRP1 VWC2L CCBE1 FBN1 DKK1

1.13e-05412165GO:0090287
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

LRP1 VWC2L LRP4 CCBE1 LTBP2 FBN1 DKK1

1.48e-051186167GO:0007167
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

LRP1 LRP4

1.58e-058162GO:0150094
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP1 VWC2L LTBP2 FBN1 DKK1

1.64e-05445165GO:0141091
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 VWC2L FBN1 DKK1

2.00e-05218164GO:0090101
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

LRP1 VWC2L LTBP2 FBN1 DKK1

2.41e-05482165GO:0007178
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

LRP1 VWC2L CCBE1 LTBP2 FBN1 DKK1

2.70e-05850166GO:0071363
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

VWC2L FBN1 DKK1

3.03e-0580163GO:0030514
GeneOntologyBiologicalProcessresponse to growth factor

LRP1 VWC2L CCBE1 LTBP2 FBN1 DKK1

3.35e-05883166GO:0070848
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 VWC2L FBN1 DKK1

1.22e-04347164GO:0090092
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

VWC2L FBN1 DKK1

1.32e-04131163GO:0030510
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

VWC2L FBN1 DKK1

1.97e-04150163GO:0090288
GeneOntologyBiologicalProcessnegative regulation of neuron projection development

LRP1 LRP4 DKK1

2.80e-04169163GO:0010977
GeneOntologyBiologicalProcesspositive regulation of vascular associated smooth muscle cell migration

LRP1 PCSK5

3.50e-0436162GO:1904754
GeneOntologyBiologicalProcessappendage morphogenesis

PCSK5 LRP4 DKK1

3.65e-04185163GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

PCSK5 LRP4 DKK1

3.65e-04185163GO:0035108
GeneOntologyBiologicalProcessnegative regulation of SMAD protein signal transduction

LRP1 DKK1

4.11e-0439162GO:0060392
GeneOntologyBiologicalProcessnegative regulation of Wnt signaling pathway

LRP1 LRP4 DKK1

4.26e-04195163GO:0030178
GeneOntologyBiologicalProcessamyloid-beta clearance

LRP1 LRP4

4.33e-0440162GO:0097242
GeneOntologyBiologicalProcessBMP signaling pathway

VWC2L FBN1 DKK1

4.38e-04197163GO:0030509
GeneOntologyBiologicalProcessnegative regulation of cell junction assembly

LRP1 DKK1

4.55e-0441162GO:1901889
GeneOntologyBiologicalProcesscirculatory system development

LRP1 PCSK5 SRPK2 CCBE1 FBN1 DKK1

5.02e-041442166GO:0072359
GeneOntologyBiologicalProcessresponse to BMP

VWC2L FBN1 DKK1

5.66e-04215163GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

VWC2L FBN1 DKK1

5.66e-04215163GO:0071773
GeneOntologyBiologicalProcesslimb development

PCSK5 LRP4 DKK1

6.38e-04224163GO:0060173
GeneOntologyBiologicalProcessappendage development

PCSK5 LRP4 DKK1

6.38e-04224163GO:0048736
GeneOntologyBiologicalProcessnegative regulation of ossification

LRP4 DKK1

6.76e-0450162GO:0030279
GeneOntologyBiologicalProcessnegative regulation of cell projection organization

LRP1 LRP4 DKK1

7.15e-04233163GO:0031345
GeneOntologyBiologicalProcesspresynapse assembly

LRP4 DKK1

9.73e-0460162GO:0099054
GeneOntologyBiologicalProcessregulation of vascular associated smooth muscle cell migration

LRP1 PCSK5

1.11e-0364162GO:1904752
GeneOntologyBiologicalProcessrespiratory tube development

PCSK5 CCBE1 FBN1

1.13e-03273163GO:0030323
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

LRP1 LTBP2 FBN1

1.17e-03276163GO:0007179
GeneOntologyBiologicalProcessvascular associated smooth muscle cell migration

LRP1 PCSK5

1.32e-0370162GO:1904738
GeneOntologyBiologicalProcesspresynapse organization

LRP4 DKK1

1.44e-0373162GO:0099172
GeneOntologyBiologicalProcessregulation of cell junction assembly

LRP1 LRP4 DKK1

1.61e-03309163GO:1901888
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

LRP1 PCSK5 LRP4 ARHGEF10L DKK1

1.61e-031189165GO:0044087
GeneOntologyBiologicalProcesscoronary vasculature development

LRP1 PCSK5

1.85e-0383162GO:0060976
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell migration

LRP1 PCSK5

1.85e-0383162GO:0014911
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

LRP1 LTBP2 FBN1

2.05e-03336163GO:0071560
GeneOntologyBiologicalProcessregulation of SMAD protein signal transduction

LRP1 DKK1

2.17e-0390162GO:0060390
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

LRP1 LTBP2 FBN1

2.17e-03343163GO:0071559
GeneOntologyBiologicalProcessheart development

LRP1 PCSK5 FBN1 DKK1

2.30e-03757164GO:0007507
GeneOntologyBiologicalProcessregulation of neuron apoptotic process

LRP1 SRPK2 DKK1

2.40e-03355163GO:0043523
GeneOntologyBiologicalProcessregulation of receptor internalization

LRP1 DKK1

2.42e-0395162GO:0002090
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway

LRP1 LRP4 DKK1

2.65e-03368163GO:0030111
GeneOntologyBiologicalProcesskidney development

PCSK5 LRP4 FBN1

2.74e-03372163GO:0001822
GeneOntologyBiologicalProcessrenal system development

PCSK5 LRP4 FBN1

3.04e-03386163GO:0072001
GeneOntologyBiologicalProcessSMAD protein signal transduction

LRP1 DKK1

3.22e-03110162GO:0060395
GeneOntologyBiologicalProcesstube development

LRP1 PCSK5 SRPK2 CCBE1 FBN1

3.34e-031402165GO:0035295
GeneOntologyBiologicalProcessneuron apoptotic process

LRP1 SRPK2 DKK1

3.68e-03413163GO:0051402
GeneOntologyBiologicalProcesshair follicle development

LRP4 DKK1

4.01e-03123162GO:0001942
GeneOntologyBiologicalProcesspositive regulation of neuron differentiation

VWC2L DKK1

4.01e-03123162GO:0045666
GeneOntologyBiologicalProcessmolting cycle process

LRP4 DKK1

4.20e-03126162GO:0022404
GeneOntologyBiologicalProcesshair cycle process

LRP4 DKK1

4.20e-03126162GO:0022405
GeneOntologyBiologicalProcesspositive regulation of protein localization to membrane

LRP1 LRP4

4.46e-03130162GO:1905477
HumanPhenoMicrospherophakia

LTBP2 FBN1

9.70e-06472HP:0030961
HumanPhenoIridodonesis

LTBP2 FBN1

1.62e-05572HP:0100693
HumanPhenoSpherophakia

LTBP2 FBN1

1.62e-05572HP:0034375
HumanPhenoAplasia/Hypoplasia of the lens

LTBP2 FBN1

1.69e-041572HP:0008063
HumanPhenoAbnormality of lens shape

LTBP2 FBN1

2.45e-041872HP:0011526
HumanPhenoShallow anterior chamber

LTBP2 FBN1

2.45e-041872HP:0000594
MousePhenoabnormal limb bud morphology

LRP1 PCSK5 LRP4 DKK1

1.60e-0691144MP:0005650
MousePhenosyndactyly

PCSK5 LRP4 ZNF366 DKK1

1.75e-0693144MP:0000564
MousePhenothick apical ectodermal ridge

LRP4 DKK1

5.58e-064142MP:0001678
MousePhenoabnormal limb development

LRP1 PCSK5 LRP4 DKK1

8.92e-06140144MP:0006279
MousePhenoabnormal digit morphology

PCSK5 LRP4 ZNF366 FBN1 DKK1

1.08e-05323145MP:0002110
MousePhenoectopic digits

LRP4 DKK1

1.39e-056142MP:0000568
MousePhenoabnormal forelimb morphology

PCSK5 LRP4 FBN1 DKK1

2.51e-05182144MP:0000550
MousePhenoabnormal autopod morphology

PCSK5 LRP4 ZNF366 FBN1 DKK1

2.68e-05390145MP:0000572
MousePhenoabnormal heart ventricle morphology

ASCC1 LRP1 PCSK5 CDC123 ZNF366 FBN1

6.63e-05793146MP:0005294
MousePhenocraniofacial phenotype

LRP1 PCSK5 LRP4 ZNF366 CCBE1 FBN1 DKK1

1.59e-041372147MP:0005382
MousePhenoabnormal craniofacial morphology

LRP1 PCSK5 LRP4 ZNF366 CCBE1 FBN1 DKK1

1.59e-041372147MP:0000428
MousePhenoabnormal apical ectodermal ridge morphology

LRP4 DKK1

2.13e-0422142MP:0001676
MousePhenopolydactyly

PCSK5 LRP4 DKK1

2.59e-04129143MP:0000562
MousePhenoabnormal limb morphology

LRP1 PCSK5 LRP4 ZNF366 FBN1 DKK1

2.80e-041028146MP:0002109
MousePhenomicrophthalmia

LRP1 VWC2L ZNF366 CCBE1

3.60e-04362144MP:0001297
MousePhenodiaphragmatic hernia

LRP1 FBN1

3.72e-0429142MP:0003924
MousePhenoabnormal eye size

LRP1 VWC2L ZNF366 CCBE1

4.12e-04375144MP:0002697
MousePhenoabnormal body wall morphology

ASCC1 LRP1 PCSK5

4.12e-04151143MP:0003385
MousePhenoabnormal ectoderm morphology

LRP4 DKK1

4.54e-0432142MP:0014139
MousePhenoabnormal metacarpal bone morphology

LRP4 FBN1

6.08e-0437142MP:0003073
MousePhenolimbs/digits/tail phenotype

LRP1 PCSK5 LRP4 ZNF366 FBN1 DKK1

8.36e-041258146MP:0005371
MousePhenoomphalocele

LRP1 PCSK5

1.25e-0353142MP:0003052
MousePhenoabsent kidney

PCSK5 LRP4

1.25e-0353142MP:0000520
MousePhenoabnormal jaw morphology

LRP4 ZNF366 FBN1 DKK1

1.51e-03530144MP:0000454
MousePhenoabnormal hindlimb morphology

PCSK5 LRP4 FBN1 DKK1

2.05e-03576144MP:0000556
MousePhenoabnormal viscerocranium morphology

LRP4 ZNF366 FBN1 DKK1

2.28e-03593144MP:0005274
MousePhenoabnormal phalanx morphology

LRP4 FBN1

2.54e-0376142MP:0005306
MousePhenoabnormal diaphragm morphology

LRP1 FBN1

2.68e-0378142MP:0002279
MousePhenoabnormal trachea morphology

PCSK5 FBN1

2.88e-0381142MP:0002282
MousePhenoabnormal abdominal wall morphology

LRP1 PCSK5

2.95e-0382142MP:0003257
MousePhenoatrioventricular septal defect

LRP1 PCSK5

3.10e-0384142MP:0010412
MousePhenoembryonic lethality between implantation and somite formation, complete penetrance

PCSK5 LTBP2 FBN1

3.31e-03311143MP:0011096
MousePhenoabnormal atrioventricular septum morphology

LRP1 PCSK5

3.32e-0387142MP:0010592
MousePhenoabnormal pelvic girdle bone morphology

PCSK5 FBN1

3.32e-0387142MP:0004509
MousePhenohunched posture

LRP4 FBN1

3.62e-0391142MP:0001505
MousePhenoembryonic lethality between implantation and somite formation

PCSK5 LTBP2 FBN1

4.25e-03340143MP:0006205
DomainEGF_CA

LRP1 LRP4 CCBE1 LTBP2 FBN1

7.72e-0986165PF07645
DomainEGF_Ca-bd_CS

LRP1 LRP4 CCBE1 LTBP2 FBN1

1.42e-0897165IPR018097
DomainEGF_CA

LRP1 LRP4 CCBE1 LTBP2 FBN1

1.58e-0899165PS01187
DomainASX_HYDROXYL

LRP1 LRP4 CCBE1 LTBP2 FBN1

1.66e-08100165PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 LRP4 CCBE1 LTBP2 FBN1

2.23e-08106165IPR000152
DomainEGF

LRP1 PCSK5 LRP4 CCBE1 LTBP2 FBN1

2.68e-08235166SM00181
DomainEGF-like_dom

LRP1 PCSK5 LRP4 CCBE1 LTBP2 FBN1

3.79e-08249166IPR000742
DomainEGF_CA

LRP1 LRP4 CCBE1 LTBP2 FBN1

4.52e-08122165SM00179
DomainEGF-like_Ca-bd_dom

LRP1 LRP4 CCBE1 LTBP2 FBN1

4.90e-08124165IPR001881
DomainGrowth_fac_rcpt_

LRP1 PCSK5 LRP4 LTBP2 FBN1

1.55e-07156165IPR009030
DomainEGF_3

LRP1 LRP4 CCBE1 LTBP2 FBN1

1.18e-06235165PS50026
DomaincEGF

LRP1 LRP4 FBN1

1.33e-0626163PF12662
DomaincEGF

LRP1 LRP4 FBN1

1.33e-0626163IPR026823
DomainEGF_1

LRP1 LRP4 CCBE1 LTBP2 FBN1

1.76e-06255165PS00022
DomainEGF-like_CS

LRP1 LRP4 CCBE1 LTBP2 FBN1

1.98e-06261165IPR013032
DomainEGF_2

LRP1 LRP4 CCBE1 LTBP2 FBN1

2.13e-06265165PS01186
DomainTB

LTBP2 FBN1

1.44e-057162PF00683
Domain-

LTBP2 FBN1

1.92e-0581623.90.290.10
DomainTB_dom

LTBP2 FBN1

2.47e-059162IPR017878
DomainTB

LTBP2 FBN1

2.47e-059162PS51364
DomainLdl_recept_b

LRP1 LRP4

6.22e-0514162PF00058
DomainLDLRB

LRP1 LRP4

6.22e-0514162PS51120
DomainLY

LRP1 LRP4

7.18e-0515162SM00135
DomainLDLR_classB_rpt

LRP1 LRP4

7.18e-0515162IPR000033
DomainEGF

LRP1 LRP4 LTBP2

1.57e-04126163PF00008
Domain-

LRP1 LRP4

5.01e-04391622.120.10.30
DomainLDLR_class-A_CS

LRP1 LRP4

5.27e-0440162IPR023415
DomainLdl_recept_a

LRP1 LRP4

6.67e-0445162PF00057
Domain-

LRP1 LRP4

6.97e-04461624.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP1 LRP4

6.97e-0446162IPR011042
DomainLDLRA_1

LRP1 LRP4

7.58e-0448162PS01209
DomainLDLa

LRP1 LRP4

7.90e-0449162SM00192
DomainLDLRA_2

LRP1 LRP4

7.90e-0449162PS50068
DomainLDrepeatLR_classA_rpt

LRP1 LRP4

7.90e-0449162IPR002172
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

LTBP2 FBN1

1.35e-0425102M39713
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP2 FBN1

2.22e-0432102MM14854
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP2 FBN1

2.98e-0437102M27134
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP2 FBN1

3.14e-0438102MM14874
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP2 FBN1

3.31e-0439102MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP2 FBN1

4.22e-0444102M26969
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP2 FBN1

4.81e-0447102M646
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LRP4 LTBP2 FBN1

1.02e-03300103M610
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

LTBP2 FBN1

1.29e-0377102MM14670
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

LTBP2 FBN1

1.91e-0394102M1041
PathwayWP_WNT_SIGNALING_PATHWAY

LRP1 DKK1

2.61e-03110102MM15977
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

LTBP2 FBN1

2.99e-03118102MM15588
Pubmed

Exome sequencing identified new mutations in a Marfan syndrome family.

LRP1 FBN1

1.98e-07216224484584
Pubmed

Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.

LTBP2 FBN1

1.98e-07216224867584
Pubmed

Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo.

LRP4 DKK1

5.95e-07316219936252
Pubmed

Exome sequencing of two Italian pedigrees with non-isolated Chiari malformation type I reveals candidate genes for cranio-facial development.

LRP4 DKK1

5.95e-07316228513615
Pubmed

LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.

LTBP2 FBN1

5.95e-07316217293099
Pubmed

Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.

PCSK5 LTBP2

5.95e-07316221700711
Pubmed

Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc.

LTBP2 FBN1

1.19e-06416221540769
Pubmed

Weill-Marchesani Syndrome

LTBP2 FBN1

1.19e-06416220301293
Pubmed

Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

LRP4 DKK1

1.98e-06516220383322
Pubmed

Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding.

LRP4 DKK1

1.98e-06516216263759
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP4

1.98e-06516219047013
Pubmed

Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

LTBP2 FBN1

2.97e-06616219182256
Pubmed

Developmental expression of latent transforming growth factor beta binding protein 2 and its requirement early in mouse development.

LTBP2 FBN1

4.16e-06716210848613
Pubmed

APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice.

LRP1 LRP4

7.13e-06916223986861
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP4

1.09e-051116224639464
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

LRP1 PCSK5 ZNF366

1.26e-0510016325807483
Pubmed

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice.

LRP1 LRP4

1.54e-051316216207730
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

LRP1 PCSK5 FBN1

2.06e-0511816321078624
Pubmed

Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.

LRP1 LRP4

2.08e-051516220205790
Pubmed

Wnt signaling in the murine diastema.

LRP4 DKK1

2.69e-051716221531785
Pubmed

Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells.

LRP4 DKK1

4.15e-052116219806668
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP4

4.15e-052116221337463
Pubmed

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

LRP1 CDC123

8.57e-053016221946350
Pubmed

Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure.

LRP4 DKK1

1.10e-043416226288816
Pubmed

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling.

LRP4 DKK1

1.10e-043416223293290
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

PCSK5 LTBP2 FBN1

1.87e-0424816324006456
Pubmed

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

LRP1 CDC123

3.23e-045816223284291
InteractionZFP41 interactions

LRP1 LRP4 FBN1

1.17e-0557163int:ZFP41
InteractionLCE3D interactions

VWC2L PCSK5 SRPK2

2.47e-0573163int:LCE3D
InteractionZNF778 interactions

LRP4 LTBP2

3.24e-0511162int:ZNF778
InteractionC17orf50 interactions

VWC2L PCSK5

3.88e-0512162int:C17orf50
GeneFamilyLow density lipoprotein receptors

LRP1 LRP4

1.71e-051392634
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_2_CELL

PCSK5 LRP4 LTBP2

3.27e-05104163M45682
CoexpressionWATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP

PCSK5 FBN1

5.94e-0519162M12084
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

LRP1 CCBE1 FBN1

7.44e-05137163M40313
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR

CCBE1 LTBP2

2.05e-0435162MM17054
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

LTBP2 FBN1

2.05e-0435162M11788
CoexpressionAIZARANI_LIVER_C21_STELLATE_CELLS_1

LRP1 CCBE1 FBN1

2.08e-04194163M39122
CoexpressionLEF1_UP.V1_UP

PCSK5 LTBP2 DKK1

2.08e-04194163M2905
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

LTBP2 FBN1

2.17e-0436162MM1212
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_UP

ASCC1 ARHGEF10L DKK1

2.21e-04198163M9929
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_UP

LRP1 PCSK5 LTBP2

2.28e-04200163M9922
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LRP1 FBN1 DKK1

2.28e-04200163M5930
CoexpressionNABA_MATRISOME

VWC2L PCSK5 CCBE1 LTBP2 FBN1

2.55e-041008165MM17056
CoexpressionNABA_MATRISOME

VWC2L PCSK5 CCBE1 LTBP2 FBN1

2.77e-041026165M5889
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

LTBP2 FBN1

4.21e-0450162M1259
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

LTBP2 FBN1

4.55e-0452162MM1118
CoexpressionLUI_THYROID_CANCER_CLUSTER_1

LRP4 FBN1

4.55e-0452162M2135
CoexpressionBOQUEST_STEM_CELL_UP

LRP1 LTBP2 FBN1

4.97e-04261163M1834
CoexpressionOISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN

LRP1 FBN1 DKK1

5.72e-04274163M289
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 PCSK5 CCBE1 LTBP2 FBN1

6.42e-091971655afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 PCSK5 CCBE1 LTBP2 FBN1

6.42e-091971651baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 PCSK5 CCBE1 LTBP2 FBN1

6.42e-091971650dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 PCSK5 CCBE1 LTBP2 FBN1

6.42e-09197165b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 PCSK5 LRP4 LTBP2 FBN1

6.76e-0919916538cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 PCSK5 LRP4 LTBP2 FBN1

6.76e-091991656b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 PCSK5 LRP4 FBN1 DKK1

6.93e-092001659d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 PCSK5 LRP4 LTBP2 FBN1

6.93e-09200165a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

LRP1 PCSK5 LRP4 LTBP2 FBN1

6.93e-09200165a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRP1 PCSK5 LRP4 LTBP2 FBN1

6.93e-0920016509537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 PCSK5 LTBP2 FBN1

3.30e-071681644b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 PCSK5 LTBP2 FBN1

3.54e-071711645d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CCBE1 LTBP2 FBN1

3.88e-07175164795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 PCSK5 LRP4 LTBP2

4.25e-0717916402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP4 CCBE1 LTBP2 FBN1

4.44e-07181164b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 PCSK5 LRP4 LTBP2

4.64e-071831647eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

LRP1 PCSK5 LTBP2 FBN1

5.06e-071871644ea486991f66c29728d127171a07b81404ec0b78
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PCSK5 CCBE1 LTBP2 FBN1

5.50e-071911641726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PCSK5 CCBE1 LTBP2 FBN1

5.50e-07191164e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 CCBE1 LTBP2 FBN1

5.62e-07192164c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 PCSK5 LTBP2 FBN1

5.62e-0719216460b1312e84f6d6448365a952469c506c00b5fe93
ToppCellLA|World / Chamber and Cluster_Paper

LRP1 PCSK5 LTBP2 FBN1

5.74e-07193164d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

LRP1 PCSK5 LTBP2 FBN1

5.86e-07194164234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 CCBE1 LTBP2 FBN1

5.98e-071951644243190ad291d56694e2155954dbaa879c9d3844
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 CCBE1 LTBP2 FBN1

5.98e-071951641236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

LRP1 PCSK5 LTBP2 FBN1

5.98e-07195164a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 CCBE1 LTBP2 FBN1

5.98e-07195164df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 PCSK5 LTBP2 FBN1

5.98e-07195164f54bc4454270ff06e85596f98199372b50d0179f
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LRP4 FBN1

6.10e-071961646bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 CCBE1 LTBP2 FBN1

6.10e-0719616442e9828222a9663525d571633e8a454c30bfa7f8
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LRP4 FBN1

6.10e-07196164c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 PCSK5 LTBP2 FBN1

6.23e-0719716471786e9432e2d649f5d86f639abb25e7102deb67
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCSK5 CCBE1 LTBP2 FBN1

6.35e-07198164a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCSK5 CCBE1 LTBP2 FBN1

6.35e-071981648b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 CCBE1 LTBP2 FBN1

6.35e-07198164bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCSK5 CCBE1 LTBP2 FBN1

6.35e-071981644739b2e4ab141c66772e61686b45614a1839483e
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 CCBE1 LTBP2 FBN1

6.35e-071981643ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

LRP1 CCBE1 LTBP2 FBN1

6.35e-071981642d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 PCSK5 LTBP2 FBN1

6.48e-071991641fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 CCBE1 FBN1 DKK1

6.48e-071991648b86c69aaf60feff53aa782559cfece7342a23de
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCBE1 LTBP2 FBN1 DKK1

6.48e-0719916493e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCBE1 LTBP2 FBN1 DKK1

6.48e-071991644d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164fd92d8250c6ad1e8bb46b303ac37f8dcf80387d8
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164311fab076f2ceb258e3970eb21e39344b894042a
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-072001648ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PCSK5 LRP4 FBN1 DKK1

6.61e-0720016408bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-0720016434f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-072001643dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellTracheal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 PCSK5 LTBP2 FBN1

6.61e-072001647ba292c30d915e66ebc8026fa76492cedf64700e
ToppCellTracheal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 PCSK5 LTBP2 FBN1

6.61e-07200164920e6036c0a9c0089d0d898673daf9dd9d7279fc
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-07200164e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 PCSK5 LTBP2 FBN1

6.61e-0720016474ad0ae592252060ee294d7483327d765a6ba1dd
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CCBE1 LTBP2 FBN1

6.61e-0720016458b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellsevere_COVID-19-cDC|World / disease group, cell group and cell class (v2)

ZNF366 FBN1 DKK1

2.22e-051561630a7e18ed8e13261c405eb6b9a183e99d8e1aac37
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PCSK5 LRP4 LTBP2

2.26e-05157163b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCBE1 LTBP2 FBN1

2.26e-05157163f147e24f2ece82e1c54750868954d09b3c461804
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCBE1 LTBP2 FBN1

2.30e-05158163e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellfacs-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ZNF366 ARHGEF10L

2.43e-0516116345591addc765760db6029ac19e80573373d1d917
ToppCellfacs-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ZNF366 ARHGEF10L

2.43e-051611638741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCellfacs-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ZNF366 ARHGEF10L

2.43e-051611639cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 CCBE1 FBN1

2.53e-05163163f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

CCBE1 LTBP2 FBN1

2.57e-051641632ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWC2L PCSK5 CCBE1

2.62e-05165163fee7f2f8d0e25c0d067adc73f8913721bd709a3e
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

CCBE1 LTBP2 FBN1

2.76e-05168163b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

CCBE1 LTBP2 FBN1

2.76e-051681638c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

CCBE1 LTBP2 FBN1

2.81e-051691638ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWC2L PCSK5 CCBE1

2.81e-051691630c341f91dc21aaf92bead18d59684d11510502ce
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ZNF366 ARHGEF10L

2.86e-05170163ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ZNF366 ARHGEF10L

2.86e-05170163a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCBE1 LTBP2 FBN1

3.02e-051731631f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCBE1 LTBP2 FBN1

3.12e-051751631799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP2 FBN1

3.17e-051761639bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

LRP1 LRP4 FBN1

3.17e-05176163ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP2 FBN1

3.17e-051761633f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWC2L PCSK5 BEND4

3.17e-05176163ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCell-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CCBE1 LTBP2 FBN1

3.34e-05179163e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCSK5 ZNF366 FBN1

3.34e-051791631ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CCBE1 LTBP2 FBN1

3.34e-0517916310fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCBE1 LTBP2 FBN1

3.39e-0518016301f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 LRP4 FBN1

3.45e-05181163091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 CCBE1 FBN1

3.51e-05182163c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 LTBP2 FBN1

3.51e-05182163d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 CCBE1 FBN1

3.51e-05182163dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellP28-Mesenchymal|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 LRP4 FBN1

3.51e-0518216369f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP4 LTBP2 FBN1

3.57e-0518316306a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CCBE1 FBN1

3.62e-05184163e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP2 ARHGEF10L FBN1

3.68e-05185163a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP2 ARHGEF10L FBN1

3.68e-051851635053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 LTBP2 FBN1

3.68e-051851638f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 PCSK5 LRP4

3.68e-051851633b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PCSK5 LTBP2 FBN1

3.68e-05185163427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CCBE1 LTBP2 FBN1

3.74e-05186163f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CCBE1 LTBP2 FBN1

3.74e-05186163a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCBE1 LTBP2 FBN1

3.74e-051861635473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRP4 CCBE1 LTBP2

3.80e-05187163c104fbfef2d0bef64077ac721edf2379fd59d547
ComputationalMetal / Ca ion binding.

LRP1 LTBP2 FBN1

2.09e-04133103MODULE_324
ComputationalECM and collagens.

LRP1 LTBP2 FBN1

9.74e-04225103MODULE_47
Drugnovobiocin sodium, USP; Down 200; 100uM; PC3; HG-U133A

LRP1 PHC3 SRPK2 FBN1

9.12e-06197164435_DN
DiseaseWeill-Marchesani syndrome

LTBP2 FBN1

8.27e-073162C0265313
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

LTBP2 FBN1

8.27e-073162C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

LTBP2 FBN1

8.27e-073162C1869114
DiseaseWeill-Marchesani syndrome

LTBP2 FBN1

1.65e-064162cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

LTBP2 FBN1

1.65e-064162DOID:0050475 (is_implicated_in)
Diseaseintraocular pressure measurement

PCSK5 LRP4 ZNF366 LTBP2 FBN1

5.59e-06509165EFO_0004695
Diseaseaortic aneurysm

LRP1 FBN1

1.24e-0510162EFO_0001666
DiseaseMarfan Syndrome

LTBP2 FBN1

1.51e-0511162C0024796
Diseaseunipolar depression, bipolar disorder, schizophrenia

PCSK5 CCBE1

5.21e-0520162EFO_0003761, MONDO_0004985, MONDO_0005090
Diseaseneuroticism measurement

VWC2L LRP4 BEND4 LTBP2 ARHGEF10L

9.03e-05909165EFO_0007660
Diseasesuicidal ideation

BEND4 LTBP2

1.11e-0429162EFO_0004320
Diseasespontaneous coronary artery dissection

LRP1 FBN1

1.27e-0431162EFO_0010820
Diseasepulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio

LRP1 CDC123

2.94e-0447162EFO_0003892, EFO_0004713, EFO_0005671
DiseaseFEV/FEC ratio

LRP1 PCSK5 CDC123 LTBP2 FBN1

3.68e-041228165EFO_0004713
Diseasepulmonary function measurement, FEV/FEC ratio

LRP1 CDC123

3.74e-0453162EFO_0003892, EFO_0004713
Diseasefeeling "fed-up" measurement

VWC2L LRP4

7.67e-0476162EFO_0009588
Diseasedescending aortic diameter

LRP1 FBN1

1.03e-0388162EFO_0021788

Protein segments in the cluster

PeptideGeneStartEntry
EEDVIYDDVPCESPD

ARHGEF10L

126

Q9HCE6
EEDEEGYCPRCQELE

BEND4

316

Q6ZU67
ECADEPCDAYEVEQT

ASCC1

41

Q8N9N2
EPKEECDERTCEPYQ

LRP1

3526

Q07954
EVQDPDYEECVPCEE

PCSK5

1026

Q92824
DPPVVYQVEDVCEEE

PHC3

581

Q8NDX5
CTDDSPDPCIEYELV

CDC123

151

O75794
EECEECPMRNTPEYE

FBN1

991

P35555
IPEDYDVCAEAPCEQ

CCBE1

86

Q6UXH8
ECVDIDECEDYGDPV

LTBP2

1256

Q14767
QPYPCAEDEECGTDE

DKK1

81

O94907
EDDDEEDCPNPEEYN

SRPK2

401

P78362
EEPELEPLCCCEYID

ZDHHC23

16

Q8IYP9
CHEEEEEDNCYEVEP

ZNF366

616

Q8N895
DCAVPECVNPVYEPE

VWC2L

151

B2RUY7
DEQDCPPRECEEDEF

LRP4

101

O75096