Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phorbol ester receptor activity	UNC13B UNC13C	5.16e-05	2	144	2	GO:0001565
GeneOntologyMolecularFunction	non-kinase phorbol ester receptor activity	UNC13B UNC13C	5.16e-05	2	144	2	GO:0001566
GeneOntologyMolecularFunction	chromatin-protein adaptor activity	EPC1 PHF14 HDGFL2 TP53BP1	2.14e-04	41	144	4	GO:0140463
GeneOntologyMolecularFunction	dynein heavy chain binding	DYNC2LI1 NISCH DNAI4	2.32e-04	17	144	3	GO:0045504
GeneOntologyMolecularFunction	calmodulin binding	UNC13B CAMK2D CAMK2G GRM4 RYR2 RYR3 UNC13C ATP2B2	2.69e-04	230	144	8	GO:0005516
GeneOntologyMolecularFunction	integrin binding	ADAMTS13 ADAMTS5 ITGA9 ITGB6 NISCH TLN1 TLN2	2.83e-04	175	144	7	GO:0005178
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR2 RYR3	3.07e-04	4	144	2	GO:0005219
GeneOntologyMolecularFunction	G protein-coupled receptor activity	PDGFRB AVPR1A OR11H7 OR11H4 NTSR1 GRM4 ADGRG4 PTH2R GPR179 OR6N1 OR2AJ1 TAS2R3 NMBR GNRHR HCRTR2 OR5F1	6.53e-04	884	144	16	GO:0004930
GeneOntologyMolecularFunction	protein kinase A regulatory subunit binding	ARFGEF2 AKAP8L RYR2	7.52e-04	25	144	3	GO:0034237
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR2 RYR3	7.60e-04	6	144	2	GO:0048763
GeneOntologyMolecularFunction	histone reader activity	PHF14 HDGFL2 TP53BP1	8.46e-04	26	144	3	GO:0140566
GeneOntologyCellularComponent	sarcoplasmic reticulum membrane	CAMK2D CAMK2G RYR2 RYR3	2.65e-04	45	145	4	GO:0033017
GeneOntologyCellularComponent	cell cortex	UNC13B SPIRE1 OCM2 DENND2B COTL1 ANLN UNC13C MARK2 FMNL1 DYNC1H1	2.71e-04	371	145	10	GO:0005938
GeneOntologyCellularComponent	piccolo histone acetyltransferase complex	EPC2 EPC1	2.84e-04	4	145	2	GO:0032777
GeneOntologyCellularComponent	sarcoplasmic reticulum	CAMK2D CAMK2G CMYA5 RYR2 RYR3	3.70e-04	88	145	5	GO:0016529
GeneOntologyCellularComponent	calcium- and calmodulin-dependent protein kinase complex	CAMK2D CAMK2G	4.71e-04	5	145	2	GO:0005954
GeneOntologyCellularComponent	dynein complex	DNAH14 DYNC2LI1 DNAI4 DYNC1H1	5.37e-04	54	145	4	GO:0030286
Domain	DUF1041	UNC13B CADPS UNC13C	4.35e-06	5	143	3	SM01145
Domain	Munc13_1	UNC13B CADPS UNC13C	1.50e-05	7	143	3	IPR014770
Domain	MHD1	UNC13B CADPS UNC13C	1.50e-05	7	143	3	PS51258
Domain	DUF1041	UNC13B CADPS UNC13C	1.50e-05	7	143	3	PF06292
Domain	CAPS_dom	UNC13B CADPS UNC13C	1.50e-05	7	143	3	IPR010439
Domain	-	TLN1 TLN2	5.82e-05	2	143	2	1.20.1420.10
Domain	Enhancer_polycomb	EPC2 EPC1	5.82e-05	2	143	2	IPR024943
Domain	VBS	TLN1 TLN2	5.82e-05	2	143	2	PF08913
Domain	Enhancer_polycomb_C	EPC2 EPC1	5.82e-05	2	143	2	IPR009607
Domain	Vinculin-bd_dom	TLN1 TLN2	5.82e-05	2	143	2	IPR015009
Domain	Talin_cent	TLN1 TLN2	5.82e-05	2	143	2	IPR015224
Domain	E_Pc_C	EPC2 EPC1	5.82e-05	2	143	2	PF06752
Domain	Talin_middle	TLN1 TLN2	5.82e-05	2	143	2	PF09141
Domain	Ryanodine_rcpt	RYR2 RYR3	1.74e-04	3	143	2	IPR003032
Domain	Talin-1	TLN1 TLN2	1.74e-04	3	143	2	IPR015710
Domain	Ryanrecept_TM4-6	RYR2 RYR3	1.74e-04	3	143	2	IPR009460
Domain	Unc-13	UNC13B UNC13C	1.74e-04	3	143	2	IPR027080
Domain	RyR	RYR2 RYR3	1.74e-04	3	143	2	PF02026
Domain	RR_TM4-6	RYR2 RYR3	1.74e-04	3	143	2	PF06459
Domain	Ryan_recept	RYR2 RYR3	1.74e-04	3	143	2	IPR013333
Domain	ILWEQ_dom	TLN1 TLN2	3.46e-04	4	143	2	IPR002558
Domain	CaMKII_AD	CAMK2D CAMK2G	3.46e-04	4	143	2	PF08332
Domain	ILWEQ	TLN1 TLN2	3.46e-04	4	143	2	SM00307
Domain	FERM_f0	TLN1 TLN2	3.46e-04	4	143	2	PF16511
Domain	ILWEQ	TLN1 TLN2	3.46e-04	4	143	2	PD011820
Domain	-	TLN1 TLN2	3.46e-04	4	143	2	1.20.1410.10
Domain	I_LWEQ	TLN1 TLN2	3.46e-04	4	143	2	PF01608
Domain	I_LWEQ	TLN1 TLN2	3.46e-04	4	143	2	PS50945
Domain	Ca/CaM-dep_prot_kinase-assoc	CAMK2D CAMK2G	3.46e-04	4	143	2	IPR013543
Domain	FERM_f0	TLN1 TLN2	3.46e-04	4	143	2	IPR032425
Domain	KIND_dom	FRMPD2 SPIRE1	5.73e-04	5	143	2	IPR011019
Domain	Munc13_dom-2	UNC13B UNC13C	5.73e-04	5	143	2	IPR014772
Domain	KIND	FRMPD2 SPIRE1	5.73e-04	5	143	2	SM00750
Domain	MHD2	UNC13B UNC13C	5.73e-04	5	143	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13C	5.73e-04	5	143	2	IPR019558
Domain	Membr_traf_MHD	UNC13B UNC13C	5.73e-04	5	143	2	PF10540
Domain	KIND	FRMPD2 SPIRE1	5.73e-04	5	143	2	PS51377
Domain	RIH_assoc-dom	RYR2 RYR3	8.56e-04	6	143	2	IPR013662
Domain	Ins145_P3_rec	RYR2 RYR3	8.56e-04	6	143	2	PF08709
Domain	RIH_assoc	RYR2 RYR3	8.56e-04	6	143	2	PF08454
Domain	RIH_dom	RYR2 RYR3	8.56e-04	6	143	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 RYR3	8.56e-04	6	143	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 RYR3	8.56e-04	6	143	2	IPR015925
Domain	-	RYR2 RYR3	8.56e-04	6	143	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 RYR3	8.56e-04	6	143	2	PF01365
Domain	-	PLEKHF1 FRMPD2 TBC1D2 CADPS ANLN TLN1 TLN2 AGAP9 ACAP2 ARHGAP21	8.72e-04	391	143	10	2.30.29.30
Domain	Vinculin/catenin	TLN1 TLN2	1.19e-03	7	143	2	IPR006077
Domain	EPL1	EPC2 EPC1	1.58e-03	8	143	2	PF10513
Domain	Enhancer_polycomb-like_N	EPC2 EPC1	1.58e-03	8	143	2	IPR019542
Domain	PH_dom-like	PLEKHF1 FRMPD2 TBC1D2 CADPS ANLN TLN1 TLN2 AGAP9 ACAP2 ARHGAP21	1.66e-03	426	143	10	IPR011993
Domain	-	DHX16 SETX ATAD5 BMS1 PSMC4 RNF213 NDUFA10 DNAH14 DYNC2LI1 DDX60L AGAP9 POLQ SNRNP200 DYNC1H1	1.78e-03	746	143	14	3.40.50.300
Domain	FERM_N	FRMPD2 TLN1 TLN2	2.03e-03	33	143	3	IPR018979
Domain	FERM_N	FRMPD2 TLN1 TLN2	2.03e-03	33	143	3	PF09379
Domain	DEAD/DEAH_box_helicase_dom	DHX16 DDX60L POLQ SNRNP200	2.38e-03	73	143	4	IPR011545
Domain	DEAD	DHX16 DDX60L POLQ SNRNP200	2.38e-03	73	143	4	PF00270
Domain	MIR	RYR2 RYR3	2.52e-03	10	143	2	PF02815
Domain	MIR_motif	RYR2 RYR3	2.52e-03	10	143	2	IPR016093
Domain	MIR	RYR2 RYR3	2.52e-03	10	143	2	PS50919
Domain	MIR	RYR2 RYR3	2.52e-03	10	143	2	SM00472
Domain	-	CAMK2D CAMK2G	4.30e-03	13	143	2	3.10.450.50
Domain	PX	SNX17 NISCH SNX2	4.63e-03	44	143	3	SM00312
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DYNC1H1	4.99e-03	14	143	2	IPR024317
Domain	Dynein_HC_stalk	DNAH14 DYNC1H1	4.99e-03	14	143	2	IPR024743
Domain	IRS	TLN1 TLN2	4.99e-03	14	143	2	PF02174
Domain	IRS_PTB	TLN1 TLN2	4.99e-03	14	143	2	IPR002404
Domain	MT	DNAH14 DYNC1H1	4.99e-03	14	143	2	PF12777
Domain	AAA_8	DNAH14 DYNC1H1	4.99e-03	14	143	2	PF12780
Domain	AAA	ATAD5 PSMC4 RNF213 SNRNP200 DYNC1H1	5.04e-03	144	143	5	SM00382
Domain	AAA+_ATPase	ATAD5 PSMC4 RNF213 SNRNP200 DYNC1H1	5.04e-03	144	143	5	IPR003593
Domain	FERM_M	FRMPD2 TLN1 TLN2	5.24e-03	46	143	3	PF00373
Domain	P-loop_NTPase	DHX16 SETX ATAD5 BMS1 PSMC4 RNF213 NDUFA10 DNAH14 DYNC2LI1 DDX60L AGAP9 POLQ SNRNP200 DYNC1H1	5.58e-03	848	143	14	IPR027417
Domain	PH	PLEKHF1 TBC1D2 CADPS ANLN AGAP9 ACAP2 ARHGAP21	5.64e-03	278	143	7	SM00233
Domain	DHC_fam	DNAH14 DYNC1H1	5.73e-03	15	143	2	IPR026983
Domain	Dynein_heavy	DNAH14 DYNC1H1	5.73e-03	15	143	2	PF03028
Domain	Dynein_heavy_dom	DNAH14 DYNC1H1	5.73e-03	15	143	2	IPR004273
Domain	NTF2-like_dom	CAMK2D CAMK2G	5.73e-03	15	143	2	IPR032710
Domain	PH_DOMAIN	PLEKHF1 TBC1D2 CADPS ANLN AGAP9 ACAP2 ARHGAP21	5.75e-03	279	143	7	PS50003
Domain	PH_domain	PLEKHF1 TBC1D2 CADPS ANLN AGAP9 ACAP2 ARHGAP21	5.86e-03	280	143	7	IPR001849
Domain	-	FRMPD2 TLN1 TLN2	6.26e-03	49	143	3	1.20.80.10
Domain	PX	SNX17 NISCH SNX2	6.26e-03	49	143	3	PF00787
Domain	FERM_central	FRMPD2 TLN1 TLN2	6.26e-03	49	143	3	IPR019748
Domain	FERM_domain	FRMPD2 TLN1 TLN2	6.26e-03	49	143	3	IPR000299
Domain	PX	SNX17 NISCH SNX2	6.62e-03	50	143	3	PS50195
Domain	FERM/acyl-CoA-bd_prot_3-hlx	FRMPD2 TLN1 TLN2	6.62e-03	50	143	3	IPR014352
Domain	FERM_1	FRMPD2 TLN1 TLN2	6.62e-03	50	143	3	PS00660
Domain	FERM_2	FRMPD2 TLN1 TLN2	6.62e-03	50	143	3	PS00661
Domain	FERM_3	FRMPD2 TLN1 TLN2	6.62e-03	50	143	3	PS50057
Domain	Band_41_domain	FRMPD2 TLN1 TLN2	6.62e-03	50	143	3	IPR019749
Domain	B41	FRMPD2 TLN1 TLN2	6.62e-03	50	143	3	SM00295
Domain	-	SNX17 NISCH SNX2	7.00e-03	51	143	3	3.30.1520.10
Domain	Phox	SNX17 NISCH SNX2	7.39e-03	52	143	3	IPR001683
Pathway	REACTOME_ION_HOMEOSTASIS	CAMK2D CAMK2G RYR2 RYR3 ATP2B2	5.16e-05	54	106	5	M27460
Pathway	REACTOME_ION_HOMEOSTASIS	CAMK2D CAMK2G RYR2 RYR3 ATP2B2	5.16e-05	54	106	5	MM15202
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	PDGFRB AVPR1A CAMK2D CAMK2G NTSR1 RYR2 RYR3 ATP2B2	5.81e-05	178	106	8	M2890
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	ITGA9 ITGB6 TLN1 TLN2	7.12e-05	30	106	4	M47724
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX16 UTP6 SETX CAMK2D CAMK2G U2SURP SNX17 BMS1 NOL11 PSMC4 HUWE1 COTL1 AKAP8L ANLN FANCI TLN1 WDR82 DDX60L HERC2 SNRNP200 IMMT CHTOP DYNC1H1 TP53BP1	2.76e-09	1353	147	24	29467282
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DHX16 UTP6 PDGFRB U2SURP BMS1 NOL11 PSMC4 FASTKD5 HUWE1 MDH1 CMYA5 NDUFA10 PRDM2 FANCI TLN1 TLN2 PNPLA8 SNRNP200 IMMT CHTOP DYNC1H1 SNX2 SOAT1 CPSF7	7.53e-09	1425	147	24	30948266
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	TET2 U2SURP BMS1 PSMC4 HUWE1 MDH1 AKAP8L PDCD4 CEP170 ANLN WDR82 ACAP2 SNRNP200 CHTOP CPSF7	1.43e-08	551	147	15	34728620
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	UNC13B TET2 ACTR8 ZBTB38 PDGFRB FEZF2 ARFGEF2 HUWE1 MDH1 CMYA5 NDUFA10 AKAP8L RYR3 CADPS NISCH TLN2 HERC2 SNRNP200 IMMT TARBP1 ARHGAP21 DYNC1H1	2.56e-08	1285	147	22	35914814
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SETX U2SURP ARFGEF2 PSMC4 HUWE1 ANLN FANCI TLN1 TLN2 MARK2 SNRNP200 DYNC1H1 SNX2 CPSF7	2.01e-07	582	147	14	20467437
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	DHX16 AFTPH TBC1D2 ARFGEF2 HUWE1 AKAP8L PRDM2 ANLN AFF1 TLN2 PHF14 MARK2 KAT6B SNRNP200 SNX2 TP53BP1	2.02e-07	774	147	16	15302935
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	AMD1 EPC2 ATAD5 HUWE1 MDH1 HAUS2 PDCD4 CEP170 CCDC66 ANLN TLN1 EPC1 ACAP2 CPSF7	6.86e-07	645	147	14	25281560
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAP9 CAMK2D CAMK2G ARFGEF2 SPIRE1 MDH1 ARPC5 COTL1 CEP170 CADPS NISCH TLN1 TLN2 MARK2 ATP2B2 SNRNP200 IMMT ARHGAP21 DYNC1H1 SNX2 CPSF7	6.95e-07	1431	147	21	37142655
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DHX16 UTP6 U2SURP BMS1 NOL11 HUWE1 CEP170 FANCI TLN1 HERC2 SNRNP200 IMMT DYNC1H1 TP53BP1	7.93e-07	653	147	14	22586326
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TET2 EPC2 SETX CAMK2G U2SURP PSMC4 E2F8 PRDM2 CEP170 ANLN FANCI TLN1 WDR82 SNRNP200 CHTOP DYNC1H1 TP53BP1 CPSF7	1.06e-06	1103	147	18	34189442
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	UNC13B DHX16 EMC7 SETX BMS1 TASP1 NOL11 PSMC4 NDUFA10 AKAP8L MTFMT CEP170 TLN1 WDR82 MARK2 NOSTRIN HERC2 CHTOP DYNC1H1 CPSF7	1.44e-06	1371	147	20	36244648
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	PSMC4 RNF213 HUWE1 PDCD4 ANLN TLN1 SNRNP200 DYNC1H1 TP53BP1 CPSF7	1.64e-06	332	147	10	32786267
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	DHX16 U2SURP PSMC4 SPIRE1 ANLN TLN1 HDGFL2 SNRNP200 CHTOP DYNC1H1 TP53BP1 CPSF7	1.79e-06	506	147	12	30890647
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	CAMK2D CAMK2G U2SURP PSMC4 HUWE1 MDH1 ARPC5 COTL1 AKAP8L CEP170 FANCI NISCH TLN1 HDGFL2 SNRNP200 DYNC1H1 SNX2 CPSF7	1.88e-06	1149	147	18	35446349
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	U2SURP PSMC4 ARPC5 PDCD4 STAT2 TLN1 KAT6B ATP2B2 HDGFL2 SNRNP200 CHTOP DYNC1H1	3.37e-06	538	147	12	28524877
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	DHX16 AKAP8L CEP170 ANLN TLN1 ACAP2 DYNC1H1 SNX2 TP53BP1 CPSF7	3.37e-06	360	147	10	33111431
Pubmed	Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.	UNC13B CADPS UNC13C	4.08e-06	8	147	3	25609709
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	AMD1 MBLAC2 FRMPD2 RNF213 SPIRE1 HUWE1 NAALADL2 ARPC5 DENND2B DNAH14 CEP170 ZBTB46 SLC35A3 TXNL4B AFF1 KYAT3 PHF14 NRG3 KAT6B SNX2	4.98e-06	1489	147	20	28611215
Pubmed	Functional genomics identifies therapeutic targets for MYC-driven cancer.	CAMK2D CAMK2G ARFGEF2 SULF2 SNRNP200 GNRHR	5.25e-06	103	147	6	22623531
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	U2SURP HUWE1 TLN2 HERC2 KAT6B DYNC1H1	5.55e-06	104	147	6	9205841
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	UNC13B CAMK2D CAMK2G BMS1 PSMC4 HUWE1 NDUFA10 ARPC5 PDCD4 FANCI MARK2 HERC2 SNRNP200 IMMT TARBP1 TP53BP1	5.97e-06	1005	147	16	19615732
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	TBC1D9B CAMK2D CAMK2G U2SURP HUWE1 FANCI WDR82 HERC2 SNRNP200	8.02e-06	313	147	9	38270169
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	SETX AFTPH HUWE1 PDCD4 ANLN FANCI EPC1 TLN2 MARK2 SNX2 TP53BP1	1.05e-05	503	147	11	16964243
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	DHX16 UTP6 BMS1 NOL11 RNF213 HUWE1 CEP170 PHF14 DDX60L	1.28e-05	332	147	9	25693804
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	PSMC4 HUWE1 CEP170 SLC35G1 TLN1 HERC2 DYNC1H1	1.32e-05	182	147	7	31067453
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	EPC2 SNX17 BMS1 NOL11 ANLN FANCI EPC1 WDR82 SNRNP200	1.51e-05	339	147	9	30415952
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EMC7 AFTPH EMC4 ATAD5 BMS1 NOL11 PSMC4 FASTKD5 NISCH TLN1 PNPLA8 MARK2 HERC2 HDGFL2 SNRNP200 IMMT SNX2 SOAT1 TP53BP1	1.76e-05	1487	147	19	33957083
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	DHX16 UTP6 EPC2 SETX RBL1 SNX17 BMS1 HUWE1 NISCH EPC1 SNRNP200 DYNC1H1 SNX2 TP53BP1	1.77e-05	857	147	14	25609649
Pubmed	The Polyploid State Plays a Tumor-Suppressive Role in the Liver.	E2F8 ANLN	1.77e-05	2	147	2	29429824
Pubmed	Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance.	CAMK2D CAMK2G	1.77e-05	2	147	2	34303021
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	1.77e-05	2	147	2	8898078
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	1.77e-05	2	147	2	14550562
Pubmed	Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure.	CAMK2D RYR2	1.77e-05	2	147	2	20479242
Pubmed	Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.	UNC13B UNC13C	1.77e-05	2	147	2	22674279
Pubmed	CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation.	CAMK2D CAMK2G	1.77e-05	2	147	2	31619570
Pubmed	Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway.	CAMK2D CAMK2G	1.77e-05	2	147	2	29992531
Pubmed	Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling.	CAMK2D CAMK2G	1.77e-05	2	147	2	26567004
Pubmed	Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy.	CAMK2D CAMK2G	1.77e-05	2	147	2	25124496
Pubmed	Stabilizing cardiac ryanodine receptor prevents the development of cardiac dysfunction and lethal arrhythmia in Ca2+/calmodulin-dependent protein kinase IIδc transgenic mice.	CAMK2D RYR2	1.77e-05	2	147	2	32007269
Pubmed	Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell.	TLN1 TLN2	1.77e-05	2	147	2	26822056
Pubmed	Extracellular rigidity sensing by talin isoform-specific mechanical linkages.	TLN1 TLN2	1.77e-05	2	147	2	26523364
Pubmed	[PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice].	CAMK2D CAMK2G	1.77e-05	2	147	2	38597448
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	1.77e-05	2	147	2	21531043
Pubmed	Rearranging exosites in noncatalytic domains can redirect the substrate specificity of ADAMTS proteases.	ADAMTS13 ADAMTS5	1.77e-05	2	147	2	22707719
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	1.77e-05	2	147	2	16678258
Pubmed	The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals.	EPC2 EPC1	1.77e-05	2	147	2	9735366
Pubmed	Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry.	EMC7 EMC4	1.77e-05	2	147	2	32111841
Pubmed	New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.	TLN1 TLN2	1.77e-05	2	147	2	22306379
Pubmed	CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic β-adrenergic stimulation.	CAMK2D RYR2	1.77e-05	2	147	2	26080362
Pubmed	The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure.	CAMK2D RYR2	1.77e-05	2	147	2	12676814
Pubmed	Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.	RYR2 RYR3	1.77e-05	2	147	2	14985349
Pubmed	CaM Kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury.	CAMK2D CAMK2G	1.77e-05	2	147	2	25193973
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SETX AFTPH ATAD5 BMS1 TASP1 NOL11 SPIRE1 NDUFA10 ARPC5 AKAP8L ANLN TLN1 PHF14 WDR82 MARK2 HERC2 HDGFL2 IMMT CHTOP	1.93e-05	1497	147	19	31527615
Pubmed	hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function.	CAMK2D CAMK2G RYR2	2.05e-05	13	147	3	26039991
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	EPC2 ACTR8 ATP7B FEZF2 ATAD5 RBL1 RNF213 FASTKD5 AKAP8L CEP170 SLC35G1 SULF2 CADPS EPC1 KAT6B CHTOP	2.17e-05	1116	147	16	31753913
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	EMC7 BMS1 PSMC4 FASTKD5 HUWE1 AKAP8L FANCI HERC2 ACAP2 SNRNP200 IMMT SOAT1	2.47e-05	657	147	12	36180527
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	MDH1 NDUFA10 COTL1 CEP170 FSIP2 CADPS TLN1 MARK2 ACAP2 IMMT DYNC1H1	2.73e-05	558	147	11	35063084
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	EMC4 CAMK2D CAMK2G U2SURP PSMC4 HUWE1 NDUFA10 COTL1 AKAP8L RYR2 CEP170 CADPS TLN2 CHTOP TP53BP1 PHACTR1	2.77e-05	1139	147	16	36417873
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	PSMC4 RNF213 MDH1 PRDM2 TLN1 TLN2 POLQ	3.10e-05	208	147	7	33230847
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DHX16 UTP6 U2SURP NOL11 HUWE1 CEP170 TLN1 MARK2 HERC2 SNRNP200 IMMT CHTOP DYNC1H1 SNX2 CPSF7	3.11e-05	1024	147	15	24711643
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	TBC1D9B ARFGEF2 HUWE1 PDCD4 FANCI WDR82 MARK2 TP53BP1	3.31e-05	288	147	8	23383273
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	RBL1 CAMK2D CAMK2G NOL11 FASTKD5 CEP170 ANLN TLN1 AFF1 WDR82 DDX60L MARK2 HDGFL2 ARHGAP21	3.41e-05	910	147	14	36736316
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	CAMK2G PLEKHF1 HUWE1 FMNL1 CHTOP DYNC1H1	3.42e-05	143	147	6	30397336
Pubmed	Defining the membrane proteome of NK cells.	ATP7B PDGFRB CAMK2D CAMK2G ARFGEF2 PSMC4 RNF213 HUWE1 FANCI NISCH HERC2 ACAP2 IMMT FMNL1 DYNC1H1 CPSF7	3.74e-05	1168	147	16	19946888
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TBC1D9B BMS1 PSMC4 RNF213 FASTKD5 HUWE1 MDH1 ARPC5 AKAP8L PDCD4 CEP170 FANCI TLN1 DDX60L SNRNP200 CHTOP DYNC1H1 SOAT1	3.96e-05	1440	147	18	30833792
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	DHX16 ACTR8 EMC4 LRRC37A3 CAMK2G PSMC4 DNAH14 SLC35A3 CCDC66 TRMT44 FANCI TLN1 MARK2 ACAP2	4.07e-05	925	147	14	28986522
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	U2SURP BMS1 HUWE1 CEP170 SNRNP200 IMMT DYNC1H1	4.56e-05	221	147	7	29991511
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	UTP6 EMC7 TBC1D9B EMC4 CAMK2D PSMC4 FASTKD5 HUWE1 FANCI NISCH TLN1 IMMT TARBP1 DYNC1H1	4.95e-05	942	147	14	31073040
Pubmed	Hdac6 regulates Tip60-p400 function in stem cells.	EPC2 SETX STAT2 EPC1	5.16e-05	48	147	4	24302573
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	TET2 NOL11 PSMC4 FASTKD5 TLN1 DDX60L HDGFL2 SNRNP200 IMMT CHTOP DYNC1H1 CPSF7	5.29e-05	711	147	12	33022573
Pubmed	Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.	TLN1 TLN2	5.31e-05	3	147	2	12422220
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR2 RYR3	5.31e-05	3	147	2	18403125
Pubmed	Interaction of calcium/calmodulin-dependent protein kinase IIdeltaC with sorcin indirectly modulates ryanodine receptor function in cardiac myocytes.	CAMK2D RYR2	5.31e-05	3	147	2	17707398
Pubmed	The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1.	CAMK2D RYR2	5.31e-05	3	147	2	34558218
Pubmed	A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression.	CD36 SOAT1	5.31e-05	3	147	2	32646003
Pubmed	Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation.	CAMK2D CAMK2G	5.31e-05	3	147	2	23283722
Pubmed	Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.	RYR2 RYR3	5.31e-05	3	147	2	29730765
Pubmed	CMYA5 establishes cardiac dyad architecture and positioning.	CMYA5 RYR2	5.31e-05	3	147	2	35449169
Pubmed	TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal.	TET2 RAG1	5.31e-05	3	147	2	37541212
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR2 RYR3	5.31e-05	3	147	2	7876312
Pubmed	Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development.	CAMK2D CAMK2G	5.31e-05	3	147	2	29079565
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR2 RYR3	5.31e-05	3	147	2	22948152
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR2 RYR3	5.31e-05	3	147	2	10788707
Pubmed	Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.	TLN1 TLN2	5.31e-05	3	147	2	18792400
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR2 RYR3	5.31e-05	3	147	2	7621815
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13C	5.31e-05	3	147	2	33105896
Pubmed	Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion.	TLN1 TLN2	5.31e-05	3	147	2	22665520
Pubmed	An essential role for talin during alpha(M)beta(2)-mediated phagocytosis.	TLN1 TLN2	5.31e-05	3	147	2	17202407
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR2 RYR3	5.31e-05	3	147	2	10473538
Pubmed	Identification of novel human tumor cell-specific CaMK-II variants.	CAMK2D CAMK2G	5.31e-05	3	147	2	9060999
Pubmed	Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells.	CAMK2D CAMK2G	5.31e-05	3	147	2	10819240
Pubmed	Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.	DYNC2LI1 DYNC1H1	5.31e-05	3	147	2	21723285
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13C	5.31e-05	3	147	2	23658173
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR2 RYR3	5.31e-05	3	147	2	18434746
Pubmed	Mechanotransduction in talin through the interaction of the R8 domain with DLC1.	TLN1 TLN2	5.31e-05	3	147	2	30028837
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR2 RYR3	5.31e-05	3	147	2	9204703
Pubmed	Calcium/calmodulin kinase II-dependent acetylcholine receptor cycling at the mammalian neuromuscular junction in vivo.	CAMK2D CAMK2G	5.31e-05	3	147	2	20844140
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR2 RYR3	5.31e-05	3	147	2	21881589
Pubmed	Vinculin and talin: focus on the myocardium.	TLN1 TLN2	5.31e-05	3	147	2	19952892
Pubmed	Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance.	CAMK2G RYR2	5.31e-05	3	147	2	23516528
Cytoband	15q15-q21	TLN2 TP53BP1	6.08e-05	4	147	2	15q15-q21
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	8.17e-05	3	95	2	287
GeneFamily	UNC13 homologs	UNC13B UNC13C	1.63e-04	4	95	2	836
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHF1 CADPS ANLN AGAP9 ACAP2 ARHGAP21	7.62e-04	206	95	6	682
GeneFamily	Dyneins, cytoplasmic	DYNC2LI1 DYNC1H1	2.05e-03	13	95	2	538
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMPD2 TLN1 TLN2	2.30e-03	50	95	3	1293
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UNC13B FEZF2 AVPR1A FRMPD2 GRM4 UNC13C HCRTR2	6.86e-07	150	147	7	2ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B ITGA9 PKDREJ PTH2R TLN2 UNC13C ATP2B2	9.72e-07	158	147	7	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B ITGA9 PKDREJ PTH2R TLN2 UNC13C ATP2B2	9.72e-07	158	147	7	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CMYA5 NAALADL2 CD36 AFF1 UNC13C SNX2 PHACTR1	3.80e-06	194	147	7	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	TET2 RNF213 STAT2 TLN1 DDX60L FMNL1 DYNC1H1	4.35e-06	198	147	7	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 SETX RNF213 STAT2 PRDM2 DDX60L DYNC1H1	4.65e-06	200	147	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Unfolded_protein_responsible_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	UTP6 MAP9 EMC7 PSMC4 MDH1 TXNL4B PNPLA8	4.65e-06	200	147	7	bc479baca21f0ff19a1c4efdb9530f289a1ab115
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATAD5 RBL1 E2F8 ANLN FANCI LRRC20 POLQ	4.65e-06	200	147	7	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 E2F8 OR2AJ1 ANLN FANCI POLQ	1.96e-05	167	147	6	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RBM44 ATAD5 TASP1 COTL1 GPR179 FANCI	2.10e-05	169	147	6	20fbf78382fb0ba9a63ab1aa0abc615476994ac5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	2.47e-05	174	147	6	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	RSV-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	PDGFRB TBC1D2 RNF213 STAT2 TLN2 DDX60L	2.55e-05	175	147	6	ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCell	RSV-Healthy-1\|RSV / Virus stimulation, Condition and Cluster	PDGFRB TBC1D2 RNF213 STAT2 TLN2 DDX60L	2.55e-05	175	147	6	ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNC13B FEZF2 CAMK2D GRM4 RYR3 HCRTR2	2.72e-05	177	147	6	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CNTLN E2F8 ANLN FANCI CD36 POLQ	2.90e-05	179	147	6	e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	ATAD5 E2F8 ANLN FANCI C18orf63 POLQ	3.18e-05	182	147	6	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATAD5 RBL1 E2F8 SULF2 ANLN FANCI	3.28e-05	183	147	6	42dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell	Dividing_Macrophages-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	3.38e-05	184	147	6	f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	3.48e-05	185	147	6	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD42 PDGFRB ADAMTS13 COLEC10 DYNC2LI1 TLN2	3.48e-05	185	147	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATAD5 RBL1 E2F8 SYCE2 SULF2 ANLN	3.48e-05	185	147	6	57c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD42 PDGFRB ADAMTS13 COLEC10 DYNC2LI1 TLN2	3.48e-05	185	147	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD42 PDGFRB ADAMTS13 COLEC10 DYNC2LI1 TLN2	3.48e-05	185	147	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	10x5'-Liver-Lymphocytic_NK-Cycling_NK\|Liver / Manually curated celltypes from each tissue	ATAD5 E2F8 SYCE2 TAS2R3 ANLN FANCI	3.81e-05	188	147	6	5eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	CAMK2G TASP1 RYR2 RYR3 PTCHD1 UNC13C	3.81e-05	188	147	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 PTH2R E2F8 SYCE2 FANCI POLQ	3.81e-05	188	147	6	f5102e8d95506c25c675094b86162a6a50087b64
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COLEC10 NAALADL2 ITGB6 RYR3 NRG3 PHACTR1	3.93e-05	189	147	6	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	ATP7B ATAD5 RBL1 E2F8 FANCI POLQ	3.93e-05	189	147	6	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	Dividing_Macrophages-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	3.93e-05	189	147	6	d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 RBL1 ANLN FANCI POLQ FMNL1	4.04e-05	190	147	6	b65383e256b04122500b742caeed0b807793851e
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 RBL1 ANLN FANCI POLQ FMNL1	4.04e-05	190	147	6	89095d3e023269d89c82e3a73550f869e3f34201
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	AVPR1A ATAD5 E2F8 ANLN FANCI POLQ	4.04e-05	190	147	6	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ATAD5 RBL1 ANLN FANCI NOSTRIN POLQ	4.04e-05	190	147	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CMYA5 NAALADL2 CD36 AFF1 UNC13C PHACTR1	4.16e-05	191	147	6	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATAD5 RBL1 E2F8 ANLN FANCI POLQ	4.16e-05	191	147	6	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA9 RYR3 ZBTB46 SULF2 CD36 NOSTRIN	4.29e-05	192	147	6	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	control-Myeloid-Immature_Neutrophils_2\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ATAD5 ITGA9 E2F8 ANLN FANCI POLQ	4.41e-05	193	147	6	33349830e9eba506470ad3661fad5e5a283d20ca
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	4.41e-05	193	147	6	e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA9 RYR3 ZBTB46 SULF2 CD36 NOSTRIN	4.41e-05	193	147	6	52e918884877b6659cdca0496390e440f73694a9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CMYA5 NAALADL2 ITGB6 AFF1 UNC13C PHACTR1	4.54e-05	194	147	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBL1 PTH2R SYCE2 SLC35G1 SULF2 ANLN	4.54e-05	194	147	6	effd38e51062b225ecabc7e1c50154e65495d559
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	CAMK2D CMYA5 RYR2 CADPS CD36 PHACTR1	4.54e-05	194	147	6	c3535f7cc0076653c72db582047cff053c322397
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	ATAD5 RBL1 E2F8 ANLN FANCI POLQ	4.67e-05	195	147	6	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ATAD5 RBL1 E2F8 ANLN FANCI POLQ	4.67e-05	195	147	6	1a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	E2F8 SYCE2 ANLN FANCI POLQ PHACTR1	4.67e-05	195	147	6	47a01b8a92eebeb34ac7f70bf1ab4613a326e24f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RYR2 CADPS NRG3 ATP2B2 TARBP1 PHACTR1	4.81e-05	196	147	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATAD5 RBL1 E2F8 ANLN FANCI POLQ	4.81e-05	196	147	6	1964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCell	Mild_COVID-19-T/NK-proliferating_T/NK\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	4.95e-05	197	147	6	5fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCell	proximal-Hematologic-Proliferating_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 TMC3 E2F8 SYCE2 ANLN FANCI	4.95e-05	197	147	6	0b1fa881abbfcc54b322fc27124db3f8947af016
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	4.95e-05	197	147	6	434a5686a103bb766e0d80038413f0e12ea3981a
ToppCell	Mild-Lymphoid-T-Proliferating_T\|Mild / Condition, Lineage, Cell class and cell subclass	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	4.95e-05	197	147	6	794517c70089da109f4c6489fe406c0ba6882b76
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	4.95e-05	197	147	6	6bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	4.95e-05	197	147	6	c0a71a9452febda433bc544e4ac0a79c43dcf13e
ToppCell	distal-Hematologic-Proliferating_NK/T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	4.95e-05	197	147	6	04b10879e48c101d1de449db0bc6b6484090b965
ToppCell	proximal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 TMC3 E2F8 SYCE2 ANLN FANCI	4.95e-05	197	147	6	0dd9058aa19d1268ebba9a65555870224b5a5978
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ATAD5 ITGA9 E2F8 ANLN FANCI POLQ	4.95e-05	197	147	6	bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCell	proximal-Hematologic-Proliferating_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 TMC3 E2F8 SYCE2 ANLN FANCI	4.95e-05	197	147	6	9243617b307acf3df40d93c41cd8d4788699a7ea
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RYR2 CADPS NRG3 ATP2B2 TARBP1 PHACTR1	5.09e-05	198	147	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	distal-2-Hematologic-Proliferating_NK/T\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.09e-05	198	147	6	a5fd710df5669c95fc5b5ef6e5cfafe6687c7b72
ToppCell	medial-2-Hematologic-Proliferating_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.09e-05	198	147	6	64a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCell	medial-Hematologic-Proliferating_Macrophage-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.09e-05	198	147	6	fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.09e-05	198	147	6	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	(0)_NK_dividing\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.09e-05	198	147	6	c5336d9b802393d6fd6f8446ea4bb6befeb97bfd
ToppCell	medial-Hematologic-Proliferating_Macrophage\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.09e-05	198	147	6	da6963184c32761c896a9b91a5321ad84b583736
ToppCell	Transverse-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	CNTLN E2F8 SYCE2 ANLN FANCI POLQ	5.23e-05	199	147	6	7cfe9b2538ea008d67343f3e8bfec3bf81200de6
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	CCDC168 DENND2B PTCHD1 ANLN LPO POLQ	5.23e-05	199	147	6	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDGFRB ADAMTS13 ADAMTS5 CNTLN CMYA5 ITGA9	5.23e-05	199	147	6	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Bronchial_Biopsy-Immune-Dendritic_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	TET2 ARPC5 COTL1 TLN1 PNPLA8 PHACTR1	5.23e-05	199	147	6	be916332291ea48e244c05ab1855f9fcd718ac54
ToppCell	COVID-19_Severe-immature_Neutrophil\|COVID-19_Severe / Disease condition and Cell class	ATAD5 ITGA9 OR6N1 ANLN FANCI POLQ	5.23e-05	199	147	6	f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.23e-05	199	147	6	a0c20b97cb38e493b47a06e9501fc165a78c61b2
ToppCell	COVID-19_Severe-immature_Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	ATAD5 ITGA9 OR6N1 ANLN FANCI POLQ	5.23e-05	199	147	6	42ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCell	Dividing_Macrophages\|World / lung cells shred on cell class, cell subclass, sample id	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.23e-05	199	147	6	5c755b6876e164dc847ef7c723f850f227cf3a87
ToppCell	distal-Hematologic-Proliferating_Macrophage\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.38e-05	200	147	6	3835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	ATAD5 CNTLN E2F8 ANLN FANCI POLQ	5.38e-05	200	147	6	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PDGFRB CAMK2G TMC3 RYR3 SLC39A12 NRG3	5.38e-05	200	147	6	7a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	ATAD5 CNTLN E2F8 ANLN FANCI POLQ	5.38e-05	200	147	6	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	RYR2 CADPS NRG3 ATP2B2 TARBP1 PHACTR1	5.38e-05	200	147	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Biopsy_Control_(H.)-Immune-Proliferating_Macrophages\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.38e-05	200	147	6	ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCell	(0)_NK_cells-(0)_NK_dividing\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATAD5 COTL1 E2F8 ANLN FANCI POLQ	5.38e-05	200	147	6	1a630bb327070ffcb111ec36bd8fd4be3627ca2a
ToppCell	distal-Hematologic-Proliferating_Macrophage-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.38e-05	200	147	6	9c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCell	Biopsy_Other_PF-Immune-Proliferating_Macrophages\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.38e-05	200	147	6	61473e8613f39a92002d5b631e6bd563735566e4
ToppCell	Biopsy_IPF-Immune-Monocytes\|Biopsy_IPF / Sample group, Lineage and Cell type	TET2 COTL1 SULF2 CD36 FMNL1 PHACTR1	5.38e-05	200	147	6	80b2b7eecc5dce9d22f9c80562e4aea83bbf0f50
ToppCell	distal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATAD5 E2F8 SYCE2 ANLN FANCI POLQ	5.38e-05	200	147	6	1b65c97e8123d0572d31525d6a10bc7f16857959
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	E2F8 RYR2 RYR3 ANLN POLQ	7.71e-05	132	147	5	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP-L6_NP_ALM_Trh\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UNC13B FEZF2 AVPR1A FRMPD2 HCRTR2	1.36e-04	149	147	5	fe9dff31a30dabd212d53d1295f9f13ff32cb217
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UNC13B FEZF2 AVPR1A GRM4 UNC13C	1.36e-04	149	147	5	558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TET2 NTSR1 COTL1 SULF2 PHACTR1	1.64e-04	155	147	5	77ae0b8d30bc3db4a73fd5340f99691a73d2684f
ToppCell	facs-Heart-RA-24m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTSR1 CMYA5 RYR2 RYR3 FGF4	1.74e-04	157	147	5	9021900d9b1a71210c9c414a9d165eaf399eb607
ToppCell	facs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTSR1 CMYA5 RYR2 RYR3 FGF4	1.74e-04	157	147	5	c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRG4 OR2AJ1 SYCE2 NOSTRIN NRG3	1.85e-04	159	147	5	d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RBL1 PLEKHF1 COTL1 PDCD4 SYCE2	1.90e-04	160	147	5	5cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM44 ATAD5 SPIRE1 SULF2 ANLN	2.07e-04	163	147	5	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM44 ATAD5 SPIRE1 SULF2 ANLN	2.07e-04	163	147	5	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 E2F8 ANLN FANCI POLQ	2.19e-04	165	147	5	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	NS-control-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RAG1 CCDC168 SULF2 FMNL1 PHACTR1	2.19e-04	165	147	5	8b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell	control-Myeloid-pDC\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RAG1 CCDC168 SULF2 FMNL1 PHACTR1	2.19e-04	165	147	5	243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 SLC35G1 ANLN FANCI POLQ	2.32e-04	167	147	5	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNC13B FEZF2 GRM4 RYR3 HCRTR2	2.38e-04	168	147	5	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 E2F8 ANLN FANCI POLQ	2.45e-04	169	147	5	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 E2F8 ANLN FANCI POLQ	2.45e-04	169	147	5	e7514956b2e4298222ec443f98b2f5289451786e
Disease	Malignant neoplasm of breast	TBC1D9B ATP7B ARFGEF2 ITGA9 PKDREJ COTL1 PDCD4 SLC39A12 SULF2 NISCH FGF4 AFF1 HERC2 NMBR KAT6B TP53BP1	4.85e-05	1074	139	16	C0006142
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	6.59e-05	3	139	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	6.59e-05	3	139	2	DOID:8545 (implicated_via_orthology)
Disease	myeloproliferative neoplasm (is_implicated_in)	TET2 PDGFRB	1.31e-04	4	139	2	DOID:2226 (is_implicated_in)
Disease	thrombotic thrombocytopenic purpura (is_marker_for)	ADAMTS13 CD36	1.31e-04	4	139	2	DOID:10772 (is_marker_for)
Disease	phospholipids in small VLDL measurement	SNX17 TXNL4B AFF1 TP53BP1	1.87e-04	60	139	4	EFO_0022146
Disease	Leukemia, Myelomonocytic, Chronic	TET2 PDGFRB	3.26e-04	6	139	2	C0023480
Disease	Autism Spectrum Disorders	AVPR1A NTSR1 RYR2 PTCHD1	7.11e-04	85	139	4	C1510586
Disease	triglycerides in large LDL measurement	TXNL4B AFF1 TP53BP1	1.10e-03	43	139	3	EFO_0022319
Disease	Cognitive impairment	NAALADL2 RYR2	1.18e-03	11	139	2	HP_0100543
Disease	triglyceride measurement, alcohol drinking	SNX17 TXNL4B AFF1 TP53BP1	1.26e-03	99	139	4	EFO_0004329, EFO_0004530
Disease	total lipids in very small VLDL measurement	SNX17 TXNL4B AFF1	1.26e-03	45	139	3	EFO_0022156
Disease	alpha fetoprotein measurement	SETX AFF1 POLQ TP53BP1	1.30e-03	100	139	4	EFO_0010583
Disease	serum gamma-glutamyl transferase measurement	CAMK2G SNX17 COLEC10 ITGA9 DENND2B RYR2 ZBTB46 TXNL4B TLN1 AFF1 ARHGAP21 TP53BP1	1.33e-03	914	139	12	EFO_0004532
Disease	triglyceride measurement, alcohol consumption measurement	SNX17 TXNL4B AFF1 TP53BP1	1.35e-03	101	139	4	EFO_0004530, EFO_0007878
Disease	Mental Retardation, X-Linked Nonsyndromic	HUWE1 PTCHD1	1.66e-03	13	139	2	C3501611
Disease	phospholipids in very small VLDL measurement	SNX17 AFF1 TP53BP1	1.81e-03	51	139	3	EFO_0022300
Disease	eating disorder, bipolar disorder	RYR2 NRG3	1.93e-03	14	139	2	EFO_0005203, MONDO_0004985
Disease	cholesterol in small VLDL measurement	SNX17 TXNL4B AFF1	2.02e-03	53	139	3	EFO_0022228
Disease	total lipids in medium VLDL	TXNL4B AFF1 TP53BP1	2.13e-03	54	139	3	EFO_0022153
Disease	infant head circumference	ZBTB38 ARFGEF2	2.22e-03	15	139	2	EFO_0004577
Disease	triglycerides in medium VLDL measurement	TXNL4B AFF1 TP53BP1	2.24e-03	55	139	3	EFO_0022155
Disease	triglycerides in LDL measurement	TXNL4B AFF1 TP53BP1	2.36e-03	56	139	3	EFO_0022320
Disease	glycoprotein measurement	SNX17 TXNL4B ARHGAP21 TP53BP1	2.46e-03	119	139	4	EFO_0004555
Disease	phospholipids in VLDL measurement	TXNL4B AFF1 TP53BP1	2.74e-03	59	139	3	EFO_0022301
Disease	total lipids in VLDL measurement	TXNL4B AFF1 TP53BP1	2.88e-03	60	139	3	EFO_0022314
Disease	free cholesterol in very large VLDL measurement	TXNL4B AFF1 TP53BP1	3.02e-03	61	139	3	EFO_0022274
Disease	free cholesterol in VLDL measurement	TXNL4B AFF1 TP53BP1	3.02e-03	61	139	3	EFO_0022276
Disease	phospholipids in large VLDL measurement	TXNL4B AFF1 TP53BP1	3.16e-03	62	139	3	EFO_0022169
Disease	triglycerides in medium LDL measurement	TXNL4B AFF1 TP53BP1	3.16e-03	62	139	3	EFO_0022322
Disease	total lipids in very large VLDL measurement	TXNL4B AFF1 TP53BP1	3.16e-03	62	139	3	EFO_0022313
Disease	phospholipids in very large VLDL measurement	TXNL4B AFF1 TP53BP1	3.16e-03	62	139	3	EFO_0022299
Disease	migraine disorder, systolic blood pressure	RNF213 PHACTR1	3.21e-03	18	139	2	EFO_0006335, MONDO_0005277
Disease	obsessive-compulsive disorder, autism spectrum disorder	PTH2R LRRC20	3.57e-03	19	139	2	EFO_0003756, EFO_0004242
Disease	cholesterol in large VLDL measurement	TXNL4B AFF1 TP53BP1	3.61e-03	65	139	3	EFO_0021902
Disease	cholesterol in very large VLDL measurement	TXNL4B AFF1 TP53BP1	3.61e-03	65	139	3	EFO_0022230
Disease	total lipids in small VLDL	TXNL4B AFF1 TP53BP1	3.93e-03	67	139	3	EFO_0022148
Disease	total lipids in large VLDL	TXNL4B AFF1 TP53BP1	3.93e-03	67	139	3	EFO_0022175
Disease	schizophrenia (implicated_via_orthology)	PDGFRB AVPR1A NRG3	4.10e-03	68	139	3	DOID:5419 (implicated_via_orthology)
Disease	free cholesterol in large VLDL measurement	TXNL4B AFF1 TP53BP1	4.10e-03	68	139	3	EFO_0022265
Disease	breast size	SNX17 CADPS KAT6B	4.27e-03	69	139	3	EFO_0004884
Disease	forced expiratory volume	TET2 ZBTB38 ATAD5 CAMK2G TASP1 ARFGEF2 CNTLN RYR2 AFF1 NMBR	4.27e-03	789	139	10	EFO_0004314
Disease	skin hydration measurement	TASP1 ARHGAP21	4.36e-03	21	139	2	EFO_0009586

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKLKSGNSAAVFMRT	ATAD5	921	Q96QE3
ISRLSDSKVKSMTSA	CEP170	1206	Q5SW79
MSKLSFRARALDASK	EPC1	1	Q9H2F5
MSKLSFRARALDAAK	EPC2	1	Q52LR7
TIDAKMASSRVTLLS	AGAP9	126	Q5VTM2
ISANKGFSRKSIMTS	CNTLN	486	Q9NXG0
FSSNTRKMTSLLEKT	ADGRG4	1791	Q8IZF6
ASSSLASSELMRKIK	ADGRG4	2336	Q8IZF6
SLKVTDAFARLMSTV	AFTPH	866	Q6ULP2
LTALMSRKTAISLFE	ACTR8	491	Q9H981
SKTSEALAKLMSLQA	ATP7B	786	P35670
KRLMSSILTSIDASK	ADAMTS5	436	Q9UNA0
RKRSLKAVVTAATMS	GRM4	856	Q14833
TKSMFVSRALEKILA	ARFGEF2	6	Q9Y6D5
ITIKAKVTRAFSTSM	ACOT12	71	Q8WYK0
LDISIARLKTSMKFV	COLEC10	131	Q9Y6Z7
QSKRRSEILKSMLSF	ACAP2	181	Q15057
LKVLVASATMDTARF	DHX16	546	O60231
KRLKKLSMSSIETAS	DENND2B	631	P78524
STIDAKMASSRVTLF	BMS1	381	Q14692
TFNSVRKSMSTVIKL	ATP2B2	601	Q01814
KLLDMTFSSKTNTLV	ADAMTS13	1256	Q76LX8
EQSKKSSLMVARSIL	AKAP8L	516	Q9ULX6
KFLVSRMSSATQVLK	ANKRD42	181	Q8N9B4
MSKNTVSSARFRKVD	ARPC5	1	O15511
KAVRFSFTIMKITIA	RAG1	621	P15918
STFSTFASRLMKKET	RBM44	691	Q6ZP01
MKRNRAISSSAISKA	CPSF7	341	Q8N684
SFFVRMKSTLTKRGL	NPAS1	246	Q99742
MRRKTELSSTAKSKA	KAT6B	571	Q8WYB5
SFTASVDRKFISLMS	NOL11	206	Q9H8H0
SLKASSTMAKSENLV	NRG3	406	P56975
ARMTASAASELILSK	CADPS	256	Q9ULU8
SMKFVSSLLTALFRD	FANCI	806	Q9NVI1
MLANLLSEKKTISFS	OR6N1	81	Q8NGY5
MLVNILSKTKAISFS	OR11H4	91	Q8NGC9
ILESAKARVTNMKTS	LRRC37A3	1281	O60309
SSSAVRMTSLKSNAK	NMBR	356	P28336
MSKKTVSCFVNFTRL	HAUS2	36	Q9NVX0
ASARLMTSEFLKKSS	MAP9	371	Q49MG5
MTSEFLKKSSSKRRT	MAP9	376	Q49MG5
AKTLMSRSRTKKFIS	NTSR1	176	P30989
LSVASSREKALLMAS	GPR179	841	Q6PRD1
NDLSIMSKFKLLSSL	HERC2	1526	O95714
ATAASSVKTRMQKLA	ANLN	136	Q9NQW6
SLMFTSKSEALLLKI	DYNC2LI1	216	Q8TCX1
VMKDFASFLLIASKS	DDX60L	1516	Q5H9U9
ASFLLIASKSVNMKK	DDX60L	1521	Q5H9U9
DMIRVLLSKLFSSAS	FSIP2	4471	Q5CZC0
GAAVIKARKLSSAMS	MDH1	231	P40925
KARKLSSAMSAAKAI	MDH1	236	P40925
ARAALDKATVLLSMS	PDCD4	291	Q53EL6
VASRFFVAMSSKGKL	FGF4	131	P08620
GSRLSKEMSKLTSNF	ITGB6	156	P18564
NKAFLDSRTRLKTAM	LPO	46	P22079
RSSFISSLSFFLKKM	FBXO39	146	Q8N4B4
IMRSFSFSTNLKKGL	IFNA7	171	P01567
LSVEALKYSMKTSSA	IMMT	571	Q16891
LSKMSASQVKDVFRF	OCM2	36	P0CE71
ELKSLTSKFMTTFSQ	LRRC20	61	Q8TCA0
SMLTSKTSTQKFFLR	HUWE1	3711	Q7Z6Z7
SSASAIRKLMRKAEL	PHF14	571	O94880
ALKMSVSKRARKASS	HDGFL2	161	Q7Z4V5
MALRLLKLAATSASA	NDUFA10	1	O95299
KRALKMDSLSSSFSS	ETAA1	81	Q9NY74
TSSLAMKVCRKDSLA	PHACTR1	411	Q9C0D0
ILKKDSSSVIQFMSR	ITGA9	926	Q13797
SSSVIQFMSRAKVKV	ITGA9	931	Q13797
MFKSTAKRARNSIVI	HCRTR2	161	O43614
IGRSKTKSESALIMF	OTOP1	336	Q7RTM1
FKSSTNLSEFVMRKI	FASTKD5	326	Q7L8L6
ASVNSRKDKSLRVMS	E2F8	256	A0AVK6
TGDAMSKRSKFALIT	COTL1	66	Q14019
ARLKTLKMTVAFATS	GNRHR	261	P30968
LINKSKSSMFQVRTL	CD36	161	P16671
KTSMNTFTLFLRIKF	FRMPD2	416	Q68DX3
EKLKSMTINFSSLNR	POLQ	1656	O75417
ERLVSSQKKSLMSTS	CMYA5	1506	Q8N3K9
SESSMFVSKRRFILK	AMD1	66	P17707
SKKTNFLRSMTALLD	CCDC66	436	A2RUB6
VRSVMLKKSLTATDF	MTFMT	331	Q96DP5
MLTKSIFKVVSSALF	DNAH14	2796	Q0VDD8
KVSTFAMRSLASLAL	MBLAC2	256	Q68D91
KRISGTSMAFKNIAS	MARK2	766	Q7KZI7
IIAASMSIKSSDKLR	FMNL1	821	O95466
FSSHRAAAMAKKALV	DND1	186	Q8IYX4
SISFFATMKATSVKG	DNAI4	66	Q5VTH9
ISTEFLALMKKVSKS	DYNC1H1	1571	Q14204
ISATFKMLESSSQKF	EMC4	116	Q5J8M3
SEFMTRLFSSKSSGK	EMC7	211	Q9NPA0
SKVMKKRVTFALTTS	CCDC168	1346	Q8NDH2
SMTASNRKCKAISLL	SLC39A12	526	Q504Y0
LNMSAALTARKTKEF	RYR2	1951	Q92736
MKTGLESVKSALRAF	RYR2	3046	Q92736
TTKKMLRASLTQATS	C18orf63	336	Q68DL7
TTMLVSRNFSAAKSL	CAMK2G	306	Q13555
ISSSKILGFSTSAKM	KYAT3	21	Q6YP21
ILGFSTSAKMSLKFT	KYAT3	26	Q6YP21
TSAKMSLKFTNAKRI	KYAT3	31	Q6YP21
KTLAFSIERIMAKTS	FEZF2	26	Q8TBJ5
TTMLATRNFSAAKSL	CAMK2D	306	Q13557
KRLNFSVELSKMSSN	PRDM2	1401	Q13029
LKSTARSSEKQALMS	PDGFRB	636	P09619
MLVNFFSKTKTISFS	OR11H7	81	Q8NGC8
LQMKSSEARKKSFST	OR2AJ1	226	Q8NGZ0
MLADLLSEKKTISFA	OR5F1	81	O95221
FLMKRLENIVSKASS	NOSTRIN	406	Q8IVI9
MSRIKSTLNSVSKAV	PNPLA8	101	Q9NP80
MIKTAKKSFVVSAAS	PLEKHF1	101	Q96S99
ATKTRLSKVFSAMLA	UTP6	121	Q9NYH9
AYRVTTKTSLSMFSK	SNX2	161	O60749
SMFSKSEFSVKRRFS	SNX2	171	O60749
KKSDFKSTLSLISIM	TRMT44	286	Q8IYL2
SKRFKSAAMLAVFAV	SOAT1	441	P35610
LKKMAKNSRTSLASA	TMC3	246	Q7Z5M5
KKTMSGTFLLRFSES	STAT2	591	P52630
KRLIFSTITSKMNLS	PSMC4	341	P43686
FKTKRMSLSDFIITT	TAS2R3	36	Q9NYW6
MAFRKISLKTTSDLV	BMT2	316	Q1RMZ1
LRSAKLSLIQFFSKM	RBL1	91	P28749
MLSTFVLGKDFTRTK	PTCHD1	771	Q96NR3
RTMFSFLTSQSKAKD	PKDREJ	2201	Q9NTG1
SSLVTTQRKLKAMSL	SETX	1881	Q7Z333
LMTNFRNSLKTKVSD	SYCE2	91	Q6PIF2
LKAFSIGKMSTAKRT	U2SURP	81	O15042
SISTKSKMTFLFANL	TBC1D9B	366	Q66K14
IKFIMSLKSFSDATA	AFF1	1026	P51825
LKSTTKMSLNERFTN	CHTOP	11	Q9Y3Y2
RESMVKLSSKLSAVS	SNX17	426	Q15036
ASFLRVSKMRLSVFL	RNF213	3576	Q63HN8
AKLMSSSVVVRLADF	UHRF1BP1L	451	A0JNW5
MKLTDSVLRSFRVAK	WDR82	1	Q6UXN9
SLMDFLDKTLSLSAK	UNC13C	1891	Q8NB66
ALNMSAALTARKTKE	RYR3	1851	Q15413
LLSAAKILADATAKM	TLN1	856	Q9Y490
LRSIARFSSKSKSMD	SPIRE1	666	Q08AE8
TLATLSVRFSATSMK	NISCH	241	Q9Y2I1
KSTVDLLTSITFFRM	UNC13B	891	O14795
LTMATTSDKLASRSK	TP53BP1	1736	Q12888
SSVRKETKLFSLFLM	UBE2Q2L	111	H0YL09
AASTRMVLISGKAAK	PTH2R	466	P49190
LASAERAALAKSLKM	TLX3	191	O43711
SISRAKIRTVKMTFV	AVPR1A	281	P37288
LFSMSLNAKTKVRGL	SNRNP200	1831	O75643
IFRKTMFNSTDIKLS	TMEM87B	61	Q96K49
SMASSKLLLAAKSLS	TLN2	1311	Q9Y4G6
SAVFAASTLVILRKM	SLC35G1	231	Q2M3R5
ILTTALFSVSMLSKK	SLC35A3	121	Q9Y2D2
KVSLSDVSTFLMSLR	TARBP1	546	Q13395
SKTSSDLSKMAAIYL	TXNL4B	46	Q9NX01
RASFKKVSDSMRTAS	ZBTB38	186	Q8NAP3
STSSQASLARFSMKK	ARHGAP21	1551	Q5T5U3
RFIKSLAERTMSVTT	TET2	1966	Q6N021
IMTTRFSLAAFKRNK	TASP1	186	Q9H6P5
ITNDSVSFFRTSKKM	SULF2	196	Q8IWU5
RAALMSKNSLLSLKA	ZBTB46	371	Q86UZ6
FFTKTISNSRKLMNI	TBC1D2	851	Q9BYX2
KLLSSFMFTEKTLQS	PP2D1	116	A8MPX8
STAIITAFIRALMSK	NAALADL2	466	Q58DX5