Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessextension of a leading process involved in cell motility in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

3.86e-062412GO:0021816
GeneOntologyBiologicalProcessmodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

3.84e-055412GO:0021815
GeneOntologyBiologicalProcesscell motility involved in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

8.04e-057412GO:0021814
GeneOntologyBiologicalProcessregulation of synapse organization

SRGAP2C SRGAP2 SRGAP2B LRRN1 ITSN1 ANAPC2

1.08e-04387416GO:0050807
GeneOntologyBiologicalProcessregulation of synapse structure or activity

SRGAP2C SRGAP2 SRGAP2B LRRN1 ITSN1 ANAPC2

1.21e-04395416GO:0050803
DomainsrGAP2

SRGAP2C SRGAP2 SRGAP2B

1.06e-083423IPR030252
DomainFCH

SRGAP2C SRGAP2 SRGAP2B SRGAP1

1.57e-0722424PF00611
DomainFCH

SRGAP2C SRGAP2 SRGAP2B SRGAP1

1.57e-0722424SM00055
DomainFCH_dom

SRGAP2C SRGAP2 SRGAP2B SRGAP1

1.90e-0723424IPR001060
DomainF_BAR

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.70e-0725424IPR031160
DomainF_BAR

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.70e-0725424PS51741
DomainLRRCT

LRRN1 TLR1

2.35e-0332422PF01463
DomainSH3_1

SRGAP2 SRGAP1 ITSN1

5.94e-03164423PF00018
DomainRhoGAP

SRGAP2 SRGAP1

8.57e-0362422SM00324
DomainRhoGAP

SRGAP2 SRGAP1

8.84e-0363422PF00620
DomainRHOGAP

SRGAP2 SRGAP1

9.11e-0364422PS50238
DomainRhoGAP_dom

SRGAP2 SRGAP1

9.11e-0364422IPR000198
Domain-

SRGAP2 SRGAP1

9.11e-03644221.10.555.10
DomainSH3

SRGAP2 SRGAP1 ITSN1

1.26e-02216423PS50002
DomainSH3

SRGAP2 SRGAP1 ITSN1

1.26e-02216423SM00326
DomainSH3_domain

SRGAP2 SRGAP1 ITSN1

1.32e-02220423IPR001452
Pubmed

Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

SRGAP2C SRGAP2 SRGAP2B

1.64e-09342322559944
Pubmed

Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.

SRGAP2C SRGAP2 SRGAP2B

6.54e-09442322559943
Pubmed

Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma.

SRGAP2 SRGAP1

1.42e-06242233984363
Pubmed

The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development.

SRGAP2C SRGAP2B

1.42e-06242231822692
Pubmed

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.

SRGAP2C SRGAP2

1.42e-06242227373832
Pubmed

Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.

SRGAP2 SRGAP1

4.27e-06342219137586
Pubmed

SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.

SRGAP2 SRGAP1

2.13e-05642233514561
Pubmed

FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.

SRGAP2 SRGAP1

2.13e-05642212736724
Pubmed

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.

SRGAP2 SRGAP1

2.13e-05642211672528
Pubmed

Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.

SRGAP2 SRGAP1

2.98e-05742221655271
Pubmed

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs.

MED13L PRRC2B

3.97e-05842227365365
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

UGP2 GPHN MAPRE3 DLGAP1 GDA SRGAP2 DNAH6 ITSN1 PRRC2B

4.30e-05143142937142655
Pubmed

Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.

SRGAP2 ITSN1

7.78e-051142231388001
Pubmed

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.

UBE2G2 ADAR

7.78e-051142224882218
Pubmed

Synapse formation by hippocampal neurons from agrin-deficient mice.

GPHN DLGAP1

7.78e-05114229882498
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

GPHN MAPRE3 SRGAP2 MAK GLRX3 MYO19 PCK2 PRRC2B

1.58e-04132142827173435
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

UGP2 CPSF4 MED13L ADAR ALOX12B PRRC2B

2.34e-0473242634732716
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

CPSF4 MED13L MORC4 PRRC2B

3.06e-0426842433640491
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

GPHN DLGAP1 GDA SRGAP2

3.67e-0428142428706196
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

GPHN CPSF4 SRGAP2 ADAR SRGAP1 ITSN1

7.67e-0491642632203420
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

GPHN SRGAP1 ANAPC2

8.45e-0415342310718198
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPHN DLGAP1 GDA SRGAP2 ITSN1 PRRC2B

9.94e-0496342628671696
Pubmed

DNA sequence and analysis of human chromosome 9.

SPINK4 MRRF PRRC2B ANAPC2

1.03e-0337042415164053
Pubmed

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells.

SRGAP2 ITSN1

1.08e-034042217540781
Pubmed

SUMO targets the APC/C to regulate transition from metaphase to anaphase.

GPHN ANAPC2

1.13e-034142229549242
CytobandEnsembl 112 genes in cytogenetic band chr7q35

OR2A25 EPHA1

1.69e-0366422chr7q35
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.47e-08232541288
GeneFamilyRho GTPase activating proteins|BCH domain containing

SRGAP2 SRGAP1

2.16e-0350252721
CoexpressionGSE8621_UNSTIM_VS_LPS_PRIMED_UNSTIM_MACROPHAGE_DN

PIGB TMEM223 UBE2G2 ADAR GLRX3

1.66e-05200425M6980
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

5.84e-07172425381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

6.73e-071774254d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

6.92e-07178425edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

7.12e-071794257394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

7.52e-071814255bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

7.52e-071814258e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

7.94e-071834257c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

7.94e-07183425848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

7.94e-07183425eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

8.37e-07185425b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

8.37e-071854259197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TRPC6

8.37e-07185425ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SRGAP2 SRGAP2B SRGAP1 ITSN1 TLR1

9.55e-07190425f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SRGAP2C SRGAP2 SRGAP2B SRGAP1 ITSN1

9.55e-071904252d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B INPP5A SRGAP1

1.01e-06192425984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SRGAP2C SRGAP2 SRGAP2B SRGAP1 ITSN1

1.06e-061944257c7091de47359760003e910cfbe63db5c99410d6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 SRGAP2B SRGAP1 ITSN1 TLR1

1.06e-06194425c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SRGAP2C SRGAP2 SRGAP2B SRGAP1 ITSN1

1.08e-06195425f289a44010788853d7726d4b5aa75f3c62186c08
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1 TLR1

1.14e-06197425dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B MED13L SRGAP1

1.23e-0620042521bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B MED13L SRGAP1

1.23e-06200425a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B MED13L SRGAP1

1.23e-06200425dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B MED13L SRGAP1

1.23e-06200425a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B MED13L SRGAP1

1.23e-062004253bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B MED13L SRGAP1

1.23e-0620042533036d21c1c82109284473a515c4f890b33fdd5c
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SPINK4 AGBL1 RASD2

1.44e-05157424370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.06e-051724246c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

PIGB LRRN1 TMEM190 DNAH6

2.11e-05173424d4cbeae262abfa30d8c5452285d3261a96875610
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.16e-05174424dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.21e-05175424a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 LRRN1 ADAR RASD2

2.31e-05177424291231b1520c135e92739e201495fe1935efa927
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.63e-05183424fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.63e-051834243c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.63e-05183424612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.63e-051834249c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.68e-051844247294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B TRPC6

2.86e-0518742424c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.92e-05188424047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellControl-Myeloid-cDC2|Control / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.04e-051904244e481e42353d47af7991744000403af2873f6a41
ToppCellControl-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.10e-0519142411dfd8f38beb294f42710cfbd355cb089e1023c0
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.10e-051914244e4887175200a57e1b041f2f131e3df774df3509
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.10e-051914242af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellIPF-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.10e-051914249fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SRGAP2 SRGAP2B SRGAP1 ITSN1

3.17e-0519242490274b85f3d612b6a6d435860cd6d049ddeb1d96
ToppCellIPF-Myeloid-cDC2|IPF / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.17e-05192424fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCellControl-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.23e-051934244cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.23e-051934243eaa0461618582a1754400624350d269d24e750a
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B MED13L

3.23e-051934243479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellILEUM-inflamed-(3)_moDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SRGAP2C SRGAP2B SRGAP1 ITSN1

3.30e-05194424c9d2acab0bbcfa9a9113cf3b9f8147403f0beb43
ToppCellIPF-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.30e-05194424accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.30e-05194424bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.30e-051944247d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B MED13L

3.37e-05195424fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 SRGAP2B SRGAP1 TLR1

3.43e-05196424cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 SRGAP2B SRGAP1 TLR1

3.50e-051974246ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.50e-05197424a902aa05e5f711bcfdd9e19749ab636b597eb116
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SRGAP2 SRGAP1 ITSN1 TLR1

3.57e-05198424c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SRGAP2C SRGAP2 SRGAP2B TLR1

3.64e-05199424744b63fba33b176ab7dde11646ccb313665505f7
ToppCell367C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DLGAP1 EPHA1 RASD2

1.05e-0497423a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell367C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DLGAP1 EPHA1 RASD2

1.05e-049742312cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ZSCAN20 PCK2 RASD2

2.33e-041274239071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GDA MAK ALOX12B

3.30e-041434235fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 TRPC6

4.17e-0415542390e629681a72baacc7981b82883866a487638dbc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 TRPC6

4.17e-04155423e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 TRPC6

4.17e-041554235a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRN1 SRGAP1 ALOX12B

4.25e-0415642358b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAK AGBL1 TLR1

4.33e-041574230fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SRGAP2C SRGAP2 SRGAP1

4.33e-04157423d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GDA MAK ALOX12B

4.66e-04161423ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GDA AGBL1 TNFRSF8

5.18e-041674233edb0570e583bb527165bcd8a4c25a042054043b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SRGAP2C SRGAP2 SRGAP2B

5.18e-04167423942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 TRPC6

5.27e-04168423315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 TRPC6

5.27e-04168423fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

DLGAP1 EPHA1 RASD2

5.27e-04168423b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

DLGAP1 EPHA1 RASD2

5.27e-041684238c95093b1ea45826f62893edd3c410fe53b563a4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 TRPC6

5.27e-04168423e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAK SPINK4 DNAH6

5.55e-041714235447b78148f7bccb727e2fc108589b2af02a5d31
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAK SPINK4 DNAH6

5.65e-04172423a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAK SPINK4 DNAH6

5.65e-041724230a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPINK4 TMEM190 ALOX12B

5.84e-041744233503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBXO40 TMEM223 ANAPC2

5.94e-041754233031f1eef3cfef8a7e5f57e567cb0868d06cac38
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TMEM190 DNAH6 EPHA1

6.04e-04176423bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAK TMEM190 DNAH6

6.24e-041784233b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

GPHN DLGAP1 AGBL1

6.45e-04180423198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPP5A TRPC6 RASD2

6.45e-04180423a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B

6.45e-04180423d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPP5A TRPC6 RASD2

6.45e-0418042363a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCellCOPD-Myeloid-DC_Mature|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B

6.55e-04181423675603a401d92cf9fdcd44e211ec899fa86a0d49
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DLGAP1 SRGAP1 TRPC6

6.55e-041814239ede19228ba5c0668a9c06c915510b95585216ef
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAK TMEM190 DNAH6

6.76e-0418342358847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCellRSV-Healthy-5|Healthy / Virus stimulation, Condition and Cluster

DNAH6 TNFRSF8 SRGAP1

6.87e-041844231e282d619ef8035437fabe0fd2aefda1c142f7f6
ToppCellRSV-Healthy-5|RSV / Virus stimulation, Condition and Cluster

DNAH6 TNFRSF8 SRGAP1

6.87e-04184423ba958f731de6c9eff60103d483e020e2c0c7af7c
ToppCellCOPD-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

DLGAP1 INPP5A SRGAP1

6.87e-04184423ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 SRGAP1 TRPC6

6.87e-041844231c857126c0ea0671f0d60b048efca288d348d653
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SRGAP2 SRGAP2B MYO19

6.98e-0418542302cbf492bc40abebaa93a3a208888afae72fbe06
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SRGAP1 ITSN1 TLR1

6.98e-041854238207f9eff113eed429e961748c6b17d672a13b33
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SRGAP2 SRGAP2B MYO19

6.98e-041854231b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SRGAP2C SRGAP2B ITSN1

7.20e-041874230099def970fbc828756fbf853eca2ce77b8cd342
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP2 SRGAP2B TLR1

7.20e-0418742317a37fc3a1d62fef3137e5ff26a84c0b8c80e124
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP2 SRGAP2B TLR1

7.20e-0418742311c773cf3dc1e725b7e4d8edd676c8a94a231d2a
DiseaseAbnormality of vision

UGP2 PIGB

2.68e-056402C4025846
Diseasefocal segmental glomerulosclerosis (implicated_via_orthology)

SRGAP1 TRPC6

3.75e-057402DOID:1312 (implicated_via_orthology)
Diseasecorpus collosum mid-posterior volume measurement

UGP2 TMEM190

5.27e-0425402EFO_0010300
Diseasestomach cancer (is_marker_for)

GDA LRRN1 ADAR

9.46e-04142403DOID:10534 (is_marker_for)
DiseaseX-12063 measurement

DLGAP1 CPSF4 AGBL1

2.05e-03186403EFO_0021283
Diseasecoronary artery calcification

MED13L DNAH6 AGBL1 TLR1

3.16e-03450404EFO_0004723
DiseaseSARS-CoV-2 antibody measurement, response to COVID-19 vaccine

MED13L ANAPC2

3.22e-0362402EFO_0803360, EFO_0803362
Diseasedehydroepiandrosterone sulphate measurement

CPSF4 TRPC6

3.86e-0368402EFO_0007001
Diseasecholelithiasis

MORC4 ADAR

6.37e-0388402EFO_0004799

Protein segments in the cluster

PeptideGeneStartEntry
PSGSYRMDMDTPHCL

EPHA1

281

P21709
KLRFGEAPMHFCEVM

ANAPC2

546

Q9UJX6
LPMPGCFRMRSHSYV

DLGAP1

481

O14490
DFKMMAFPDVWGHCP

AGBL1

526

Q96MI9
HRMSPFPLTSMDKAF

GPHN

316

Q9NQX3
GSSMFAPLKMLPSHC

MED13L

946

Q71F56
AMPAPMHCGRTKVFM

MYO19

731

Q96H55
THAAPCMLFMKGTPQ

GLRX3

141

O76003
FTNVRMGFHMPPFCS

HINT3

126

Q9NQE9
KIIMHDPFAMRPFFG

PCK2

491

Q16822
CMGDHKPVFLAFRIM

INPP5A

381

Q14642
FIRHFSMLCLPMPSE

DNAH6

2226

Q9C0G6
IMEMPSFYSHGLPRC

ADAR

476

P55265
AMDPRCKGMPLSSFI

ITSN1

1361

Q15811
FFHRDMKPENLLCMG

MAK

121

P20794
CLLHFGPEGKMMPIA

ALOX12B

341

O75342
RMLIHFGQMPACTPK

FBXO40

316

Q9UH90
QFMDMLFPGCVHLRK

MAPRE3

46

Q9UPY8
MCAAQMPPLAHIFRG

GDA

1

Q9Y2T3
SCKFMHPRFELPMGT

CPSF4

161

O95639
LMEKGIEVMFSPHPC

GSTCD

381

Q8NEC7
SMFCAMPPEYKGHQV

LRRN1

396

Q6UXK5
HPAKPISFAGCMTQM

OR2A25

86

A4D2G3
PNKSSASIFIMMPCH

PIGB

426

Q92521
FCPPMKFEFQSHMGD

SRGAP1

326

Q7Z6B7
CGMTPHKLHRMLSFG

MORC4

91

Q8TE76
MALGLKCFRMVHPTF

MRRF

1

Q96E11
VFCPPMKFEFQPHMG

SRGAP2C

336

P0DJJ0
FCPPMKFEFQPHMGD

SRGAP2B

336

P0DMP2
TRMVHMLCPSKISPF

TLR1

336

Q15399
HLMNPPNGKRCEFVM

UGP2

266

Q16851
CMAHRGEVPAMLPLK

TMEM223

156

A0PJW6
TLCPKAPDMGFEMRH

ZSCAN20

616

P17040
HMPGFLAGPCDMSKS

TMEM190

111

Q8WZ59
VFCPPMKFEFQPHMG

SRGAP2

336

O75044
FFHSVCPAGMIVKFP

TNFRSF8

126

P28908
PTYHDMLPAFMCSPK

PRRC2B

276

Q5JSZ5
AFHPRPFCMRRVKEM

RASD2

211

Q96D21
FAPCSKMGKIMRGPF

TRPC6

426

Q9Y210
MFTVDAMRKACLPGH

USP17L10

166

C9JJH3
LSPPKMRFTCEMFHP

UBE2G2

66

P60604
AGKLPFSRMPICEHM

SPINK4

26

O60575