Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intramolecular phosphotransferase activity	PGM2L1 PGAM1 PGAM2	8.22e-06	11	75	3	GO:0016868
GeneOntologyMolecularFunction	bisphosphoglycerate mutase activity	PGAM1 PGAM2	8.31e-05	4	75	2	GO:0004082
GeneOntologyMolecularFunction	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity	PGAM1 PGAM2	8.31e-05	4	75	2	GO:0046538
GeneOntologyMolecularFunction	phosphoglycerate mutase activity	PGAM1 PGAM2	8.31e-05	4	75	2	GO:0004619
GeneOntologyMolecularFunction	intramolecular transferase activity	PGM2L1 PGAM1 PGAM2	1.73e-04	29	75	3	GO:0016866
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1E TRPM4 KCNT2 CLCNKA CLCNKB	6.13e-04	182	75	5	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1E TRPM4 KCNT2 CLCNKA CLCNKB	6.45e-04	184	75	5	GO:0022832
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCNKA CLCNKB	7.49e-04	11	75	2	GO:0005247
GeneOntologyMolecularFunction	axon guidance receptor activity	HMCN2 ROBO1	1.06e-03	13	75	2	GO:0008046
GeneOntologyMolecularFunction	phosphatidylinositol-3-phosphate phosphatase activity	FIG4 MTMR3	1.23e-03	14	75	2	GO:0004438
GeneOntologyMolecularFunction	phosphatidylinositol monophosphate phosphatase activity	FIG4 MTMR3	1.42e-03	15	75	2	GO:0052744
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate phosphatase activity	FIG4 MTMR3	1.61e-03	16	75	2	GO:0106018
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	CLCNKA CLCNKB	1.83e-03	17	75	2	GO:0008308
GeneOntologyMolecularFunction	NAD binding	GPD1 NNT SORD	2.62e-03	73	75	3	GO:0051287
GeneOntologyMolecularFunction	protein homodimerization activity	GPD1 VIL1 TPST1 KARS1 NRF1 HIP1R ZNF318 TOP2A STOM	3.39e-03	815	75	9	GO:0042803
GeneOntologyMolecularFunction	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	ATP6V1B1 ATP6V1B2	3.64e-03	24	75	2	GO:0044769
GeneOntologyMolecularFunction	proton-transporting ATPase activity, rotational mechanism	ATP6V1B1 ATP6V1B2	3.64e-03	24	75	2	GO:0046961
GeneOntologyMolecularFunction	ATPase-coupled ion transmembrane transporter activity	ATP6V1B1 ATP6V1B2	3.64e-03	24	75	2	GO:0042625
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate phosphatase activity	FIG4 MTMR3	4.60e-03	27	75	2	GO:0034593
MousePheno	embryonic lethality prior to organogenesis	ZBTB34 ATP6V1B2 KMT2D KARS1 MAP1B NRF1 CCT5 GLRX3 UNC45B CCT8 MACF1 ALAS1 DRAP1 ODF2 FH TOP2A KNL1	1.57e-05	1204	63	17	MP:0013292
MousePheno	embryonic lethality prior to tooth bud stage	ZBTB34 ATP6V1B2 KMT2D KARS1 MAP1B NRF1 CCT5 GLRX3 UNC45B CCT8 MACF1 ALAS1 DRAP1 ODF2 FH TOP2A KNL1	9.22e-05	1383	63	17	MP:0013293
MousePheno	abnormal neuronal precursor cell migration	ITGA6 PLXNB2	1.19e-04	4	63	2	MP:0030956
MousePheno	embryonic lethality prior to organogenesis, complete penetrance	KARS1 MAP1B NRF1 GLRX3 UNC45B CCT8 MACF1 ALAS1 DRAP1 ODF2 FH KNL1	1.46e-04	772	63	12	MP:0014259
MousePheno	embryonic lethality prior to tooth bud stage, complete penetrance	KARS1 MAP1B NRF1 GLRX3 UNC45B CCT8 MACF1 ALAS1 DRAP1 ODF2 FH KNL1	1.59e-04	779	63	12	MP:0014257
Domain	V-ATPase_su_B/beta	ATP6V1B1 ATP6V1B2	1.47e-05	2	72	2	IPR022879
Domain	Cl_channel-K	CLCNKA CLCNKB	1.47e-05	2	72	2	IPR002250
Domain	ATPase_V1-cplx_bsu	ATP6V1B1 ATP6V1B2	1.47e-05	2	72	2	IPR005723
Domain	Phosphogly_mut1	PGAM1 PGAM2	8.75e-05	4	72	2	IPR005952
Domain	ATP_synth_asu_C	ATP6V1B1 ATP6V1B2	1.45e-04	5	72	2	IPR000793
Domain	ATPase_a/bsu_AS	ATP6V1B1 ATP6V1B2	1.45e-04	5	72	2	IPR020003
Domain	ATP-synt_ab_N	ATP6V1B1 ATP6V1B2	1.45e-04	5	72	2	PF02874
Domain	ATP-synt_ab_C	ATP6V1B1 ATP6V1B2	1.45e-04	5	72	2	PF00306
Domain	ATPase_F1/V1/A1_a/bsu_N	ATP6V1B1 ATP6V1B2	1.45e-04	5	72	2	IPR004100
Domain	ATP-synt_ab	ATP6V1B1 ATP6V1B2	1.45e-04	5	72	2	PF00006
Domain	ATPASE_ALPHA_BETA	ATP6V1B1 ATP6V1B2	1.45e-04	5	72	2	PS00152
Domain	ATPase_F1/V1/A1_a/bsu_nucl-bd	ATP6V1B1 ATP6V1B2	2.18e-04	6	72	2	IPR000194
Domain	PG/BPGM_mutase_AS	PGAM1 PGAM2	5.18e-04	9	72	2	IPR001345
Domain	Cl-channel_core	CLCNKA CLCNKB	5.18e-04	9	72	2	IPR014743
Domain	-	CLCNKA CLCNKB	5.18e-04	9	72	2	1.10.3080.10
Domain	Voltage_CLC	CLCNKA CLCNKB	5.18e-04	9	72	2	PF00654
Domain	Cl-channel_volt-gated	CLCNKA CLCNKB	5.18e-04	9	72	2	IPR001807
Domain	Chaperonin_TCP-1_CS	CCT5 CCT8	5.18e-04	9	72	2	IPR002194
Domain	PGAM	PGAM1 PGAM2	6.46e-04	10	72	2	SM00855
Domain	TCP1_1	CCT5 CCT8	6.46e-04	10	72	2	PS00750
Domain	TCP1_2	CCT5 CCT8	6.46e-04	10	72	2	PS00751
Domain	TCP1_3	CCT5 CCT8	6.46e-04	10	72	2	PS00995
Domain	Chaperone_TCP-1	CCT5 CCT8	6.46e-04	10	72	2	IPR017998
Domain	PG_MUTASE	PGAM1 PGAM2	6.46e-04	10	72	2	PS00175
Domain	-	CCT5 CCT8	7.88e-04	11	72	2	3.30.260.10
Domain	TCP-1-like_intermed	CCT5 CCT8	7.88e-04	11	72	2	IPR027410
Domain	His_Phos_1	PGAM1 PGAM2	9.43e-04	12	72	2	PF00300
Domain	His_Pase_superF_clade-1	PGAM1 PGAM2	9.43e-04	12	72	2	IPR013078
Domain	-	CCT5 CCT8	1.29e-03	14	72	2	1.10.560.10
Domain	GROEL-like_equatorial	CCT5 CCT8	1.29e-03	14	72	2	IPR027413
Domain	Cpn60/TCP-1	CCT5 CCT8	1.49e-03	15	72	2	IPR002423
Domain	Cpn60_TCP1	CCT5 CCT8	1.49e-03	15	72	2	PF00118
Domain	-	CCT5 CCT8	1.49e-03	15	72	2	3.50.7.10
Domain	GroEL-like_apical_dom	CCT5 CCT8	1.49e-03	15	72	2	IPR027409
Domain	CBS	CLCNKA CLCNKB	1.70e-03	16	72	2	SM00116
Domain	CBS_dom	CLCNKA CLCNKB	2.66e-03	20	72	2	IPR000644
Domain	CBS	CLCNKA CLCNKB	2.66e-03	20	72	2	PF00571
Domain	His_PPase_superfam	PGAM1 PGAM2	2.66e-03	20	72	2	IPR029033
Domain	CBS	CLCNKA CLCNKB	2.66e-03	20	72	2	PS51371
Domain	-	PGAM1 PGAM2	2.66e-03	20	72	2	3.40.50.1240
Domain	-	GPD1 KCNT2 NNT SORD	4.13e-03	169	72	4	3.40.50.720
Domain	NAD(P)-bd_dom	GPD1 KCNT2 NNT SORD	4.48e-03	173	72	4	IPR016040
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPM4 ATP6V1B1 ATP6V1B2 CLCNKA CLCNKB STOM	9.06e-05	176	59	6	MM15718
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPM4 ATP6V1B1 ATP6V1B2 CLCNKA CLCNKB STOM	1.12e-04	183	59	6	M997
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	KARS1 MAP1B CCT5 TK1 HNRNPM HIP1R CCT8 ITGA6 PPME1 ANKRD17 FH PLXNB2 PGAM1 NNT TOP2A KRT80 KNL1	3.96e-09	1367	75	17	32687490
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	TRIM16 VIL1 CACNA1E STRN CUX2 MAP1B MCTS1 HNRNPM ASPM MACF1 CFAP74 ZNF318 ODF2 SEPTIN10 PGAM1 PGAM2 TOP2A	8.74e-09	1442	75	17	35575683
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	PDXDC1 RTKN2 CCT5 GLRX3 MCTS1 HNRNPM CCT8 MACF1 FH PGAM1 NNT STOM SORD	1.73e-08	807	75	13	30575818
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PDXDC1 TRIM16 PARP6 ATP6V1B2 KARS1 CCT5 GLRX3 MCTS1 HNRNPM CCT8 PPME1 MACF1 DRAP1 FH SEPTIN10 SORD	6.73e-08	1455	75	16	22863883
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZBTB34 KMT2D KARS1 CCT5 GLRX3 MCTS1 CCT8 PPME1 ZNF318 TRIM24 PGAM1 TOP2A KNL1 SORD	8.88e-08	1103	75	14	34189442
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	ATP6V1B2 KARS1 CCT5 TK1 GLRX3 HNRNPM HIP1R CCT8 MACF1 TOP2A STOM	3.41e-07	707	75	11	19738201
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ATP6V1B2 KMT2D KARS1 PTPRG CCT5 SUN2 MTMR3 ITGA6 PPME1 ROBO1 COLGALT1 ODF2 KNL1	3.56e-07	1049	75	13	27880917
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	PDXDC1 ATP6V1B1 ATP6V1B2 CCT5 GLRX3 HNRNPM CCT8 PPME1 FH PGAM1 NNT SORD	3.78e-07	878	75	12	37223481
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	ATP6V1B1 ATP6V1B2 KARS1 CCT5 LGALSL SUN2 HELZ2 HIP1R CCT8 ANKRD17 STOM	4.80e-07	732	75	11	34732716
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	KARS1 MAP1B GLI2 ITGA6 MACF1 ROBO1 ODF2 TOP2A	1.08e-06	358	75	8	32460013
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	KARS1 MAP1B CCT5 HELZ2 ANKRD17 MACF1 ZNF318 FH PGAM1 NNT	1.41e-06	653	75	10	22586326
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	ATP6V1B2 KARS1 CCT5 MCTS1 CCT8 ANKRD17 MACF1 DRAP1 SEPTIN10 PGAM1 PGAM2	1.99e-06	847	75	11	35235311
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	PDXDC1 STRN HIP1R ITGA6 PLXNB2 SORD	2.91e-06	183	75	6	31932471
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	PDXDC1 VIL1 KMT2D KARS1 CCT5 HNRNPM HIP1R CCT8 MACF1 STOM	3.00e-06	711	75	10	33022573
Pubmed	A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.	STRN CCT5 CCT8 PPME1	3.04e-06	46	75	4	18782753
Pubmed	Isolation of a cDNA encoding the muscle-specific subunit of human phosphoglycerate mutase.	PGAM1 PGAM2	4.59e-06	2	75	2	2822696
Pubmed	Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.	CLCNKA CLCNKB	4.59e-06	2	75	2	8544406
Pubmed	Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit.	ATP6V1B1 ATP6V1B2	4.59e-06	2	75	2	17392376
Pubmed	Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis.	ATP6V1B1 ATP6V1B2	4.59e-06	2	75	2	29310826
Pubmed	The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.	CLCNKA CLCNKB	4.59e-06	2	75	2	27335120
Pubmed	Phosphoglycerate mutase isozyme marker for tissue differentiation in man.	PGAM1 PGAM2	4.59e-06	2	75	2	4827367
Pubmed	Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.	CLCNKA CLCNKB	4.59e-06	2	75	2	8812470
Pubmed	Presence of serum autoantibodies to vacuolar H+ -ATPase in patients with renal tubular acidosis.	ATP6V1B1 ATP6V1B2	4.59e-06	2	75	2	30821427
Pubmed	Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.	CLCNKA CLCNKB	4.59e-06	2	75	2	25919862
Pubmed	Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.	CLCNKA CLCNKB	4.59e-06	2	75	2	24863058
Pubmed	Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.	CLCNKA CLCNKB	4.59e-06	2	75	2	9916798
Pubmed	Kidney kinetics and chloride ion pumps.	CLCNKA CLCNKB	4.59e-06	2	75	2	9916791
Pubmed	Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice.	ATP6V1B1 ATP6V1B2	4.59e-06	2	75	2	17898041
Pubmed	Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.	CLCNKA CLCNKB	4.59e-06	2	75	2	38069401
Pubmed	A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.	CLCNKA CLCNKB	4.59e-06	2	75	2	20805576
Pubmed	Salt wasting and deafness resulting from mutations in two chloride channels.	CLCNKA CLCNKB	4.59e-06	2	75	2	15044642
Pubmed	Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.	ATP6V1B1 ATP6V1B2	4.59e-06	2	75	2	7945239
Pubmed	Impact of CUX2 on the female mouse liver transcriptome: activation of female-biased genes and repression of male-biased genes.	CUX2 TRIM24	4.59e-06	2	75	2	22966202
Pubmed	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.	CLCNKA CLCNKB	4.59e-06	2	75	2	8041726
Pubmed	Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax.	GPD1 KMT2D	4.59e-06	2	75	2	9247308
Pubmed	A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.	CLCNKA CLCNKB	4.59e-06	2	75	2	18648499
Pubmed	Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.	CLCNKA CLCNKB	4.59e-06	2	75	2	11014860
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	KARS1 HMCN2 MAP1B CCT5 GLRX3 SUN2 MCTS1 HNRNPM MTMR3 CCT8 COLGALT1 DRAP1 PGAM1	5.12e-06	1335	75	13	29229926
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	CCT5 HNRNPM CCT8 ANKRD17 FH TOP2A	5.29e-06	203	75	6	35012549
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	STRN MAP1B HNRNPM CCT8 ZNF318 TRIM24 PGAM2 TOP2A	5.29e-06	444	75	8	34795231
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	KARS1 MAP1B CCT5 HNRNPM ASPM CCT8 PGAM1	5.59e-06	316	75	7	31665637
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	KARS1 MAP1B CCT5 TK1 HNRNPM ASPM HIP1R CCT8 ANKRD17 MACF1 COLGALT1 TOP2A SORD	5.92e-06	1353	75	13	29467282
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	KMT2D SUN2 MCTS1 HNRNPM ANKRD17 TRIM24 STOM SORD	6.53e-06	457	75	8	32344865
Pubmed	A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.	VIL1 CCT5 TK1 CCT8 KRT80	7.81e-06	125	75	5	21654808
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PDXDC1 STRN ASPM HIP1R MACF1 COLGALT1 PGAM2 KNL1	8.26e-06	472	75	8	38943005
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	ATP6V1B2 MAP1B CCT5 HNRNPM HELZ2 CCT8 FH PGAM1 PGAM2 TOP2A	8.72e-06	803	75	10	36517590
Pubmed	A protein interaction landscape of breast cancer.	TK1 HNRNPM HIP1R PPME1 MACF1 SEPTIN10 NNT TOP2A STOM	9.04e-06	634	75	9	34591612
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	PDXDC1 MAP1B CCT5 HNRNPM CCT8 PGAM1 PGAM2 TOP2A KRT80	1.06e-05	647	75	9	26618866
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	CCT5 HIP1R CCT8 COLGALT1 SEPTIN10 TOP2A	1.08e-05	230	75	6	35449600
Pubmed	Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.	CCT5 GLRX3 HNRNPM HIP1R CCT8 ANKRD17 TOP2A STOM	1.10e-05	491	75	8	22623428
Pubmed	Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions.	SOX5 CUX2 ROBO1	1.25e-05	21	75	3	23303943
Pubmed	Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.	CLCNKA CLCNKB	1.37e-05	3	75	2	26013830
Pubmed	Characterization of genetically modified mice for phosphoglycerate mutase, a vitally-essential enzyme in glycolysis.	PGAM1 PGAM2	1.37e-05	3	75	2	33914812
Pubmed	Barttin increases surface expression and changes current properties of ClC-K channels.	CLCNKA CLCNKB	1.37e-05	3	75	2	12111250
Pubmed	Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection.	TK1 TOP2A	1.37e-05	3	75	2	25769404
Pubmed	Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.	CLCNKA CLCNKB	1.37e-05	3	75	2	17510212
Pubmed	Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis.	PGAM1 PGAM2	1.37e-05	3	75	2	32634742
Pubmed	Mouse phosphoglycerate mutase M and B isozymes: cDNA cloning, enzyme activity assay and mapping.	PGAM1 PGAM2	1.37e-05	3	75	2	11250083
Pubmed	Tissue specific expression of the splice variants of the mouse vacuolar proton-translocating ATPase a4 subunit.	ATP6V1B1 ATP6V1B2	1.37e-05	3	75	2	17971301
Pubmed	Developmental activation of phosphoglycerate mutase-2 in the testis of the mouse.	PGAM1 PGAM2	1.37e-05	3	75	2	2824255
Pubmed	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.	CLCNKA CLCNKB	1.37e-05	3	75	2	11734858
Pubmed	Barttin modulates trafficking and function of ClC-K channels.	CLCNKA CLCNKB	1.37e-05	3	75	2	16849430
Pubmed	CCNB2, TOP2A, and ASPM Reflect the Prognosis of Hepatocellular Carcinoma, as Determined by Weighted Gene Coexpression Network Analysis.	ASPM TOP2A	1.37e-05	3	75	2	32685486
Pubmed	Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance.	CLCNKA CLCNKB	1.37e-05	3	75	2	18094726
Pubmed	Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor.	CLCNKA CLCNKB	1.37e-05	3	75	2	10982849
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ATP6V1B2 GEMIN8 SUN2 HNRNPM ASPM MACF1 ROBO1 ALAS1 COLGALT1 HSPA12B TRIM24 PLXNB2 STOM	1.62e-05	1487	75	13	33957083
Pubmed	FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy.	CCT5 GLRX3 CCT8 FH PGAM1 PGAM2	1.65e-05	248	75	6	32963011
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	FOCAD TRIM16 TRPM4 ATP6V1B1 LRFN1 HNRNPM ITGA6 MACF1 FH SEPTIN10 PCDH9	1.66e-05	1061	75	11	33845483
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TRPM4 ATP6V1B2 STRN CCT5 SUN2 HELZ2 HIP1R CCT8 ANKRD17 MACF1 ZNF318 ODF2 STOM	1.74e-05	1497	75	13	31527615
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	ASPM CCT8 ANKRD17 ROBO1 ZNF318 KNL1	1.97e-05	256	75	6	33397691
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	KARS1 MAP1B TK1 HNRNPM CCT8 ANKRD17 TRIM24 TOP2A SORD	2.07e-05	704	75	9	29955894
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MAP1B CCT5 GLRX3 HNRNPM CCT8 ANKRD17 MACF1 ROBO1 PGAM1	2.16e-05	708	75	9	39231216
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	MAP1B CCT5 HNRNPM CCT8 ZNF318	2.28e-05	156	75	5	32850835
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	HMCN2 CLCNKA SUN2 HNRNPM ASPM ANKRD17 MACF1 ZNF318 TRIM24 TOP2A KNL1	2.65e-05	1116	75	11	31753913
Pubmed	Robo1 modulates proliferation and neurogenesis in the developing neocortex.	ITGA6 ROBO1 TOP2A	2.71e-05	27	75	3	24741061
Pubmed	H+-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney.	ATP6V1B1 ATP6V1B2	2.75e-05	4	75	2	29993276
Pubmed	Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption.	CLCNKA CLCNKB	2.75e-05	4	75	2	17652939
Pubmed	Deacetylation of phosphoglycerate mutase in its distinct central region by SIRT2 down-regulates its enzymatic activity.	PGAM1 PGAM2	2.75e-05	4	75	2	25195573
Pubmed	V-ATPase expression in the mouse olfactory epithelium.	ATP6V1B1 ATP6V1B2	2.75e-05	4	75	2	18667600
Pubmed	TRIM24 is an insulin-responsive regulator of P-bodies.	HNRNPM ANKRD17 TRIM24 TOP2A	2.79e-05	80	75	4	35803934
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	KARS1 MAP1B HNRNPM CCT8 PPME1 ANKRD17 MACF1 ZNF318 TOP2A KNL1	3.18e-05	934	75	10	33916271
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	KARS1 MAP1B CCT5 GLRX3 GEMIN8 MCTS1 HNRNPM CCT8 ANKRD17 MACF1 PGAM1	3.45e-05	1149	75	11	35446349
Pubmed	Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.	MAP1B WIF1 ASPM	3.75e-05	30	75	3	19054571
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 CCT5 HNRNPM BSDC1 CCT8 ROBO1 ZNF318 PCDH9 STOM	4.46e-05	777	75	9	35844135
Pubmed	Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus.	SOX5 CUX2 WIF1	4.57e-05	32	75	3	20308569
Pubmed	Renal epithelial miR-205 expression correlates with disease severity in a mouse model of congenital obstructive nephropathy.	ATP6V1B1 ATP6V1B2	4.57e-05	5	75	2	27384406
Pubmed	The protein profile of mouse mature cumulus-oocyte complex.	CCT5 CCT8	4.57e-05	5	75	2	17962088
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	TPST1 MAP1B TK1 GLRX3 SUN2 CCT8 ITGA6 ROBO1 COLGALT1 PLXNB2 STOM	5.15e-05	1201	75	11	35696571
Pubmed	CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.	PTPRG CCT5 CCT8	6.00e-05	35	75	3	23716698
Pubmed	Tracing the origin of hair follicle stem cells.	WIF1 ITGA6 KRT80	6.00e-05	35	75	3	34108685
Pubmed	Proteomic dissection of the von Hippel-Lindau (VHL) interactome.	CCT5 HNRNPM CCT8 COLGALT1	6.18e-05	98	75	4	21942715
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	GPD1 VIL1 ATP6V1B1 ATP6V1B2 CUX2 NRF1 CCT5 CCT8 STOM SORD	6.43e-05	1016	75	10	19056867
Pubmed	Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.	KARS1 HNRNPM ZNF318	6.53e-05	36	75	3	24147044
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	PDXDC1 BSDC1 ITGA6 MACF1 ROBO1 PCDH9 STOM	6.80e-05	467	75	7	30194290
Pubmed	Characterization of three growth hormone-responsive transcription factors preferentially expressed in adult female liver.	CUX2 TRIM24	6.84e-05	6	75	2	17412818
Pubmed	Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha.	MACF1 ROBO1	6.84e-05	6	75	2	12719437
Pubmed	Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin.	CCT5 CCT8	6.84e-05	6	75	2	10748209
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ATP6V1B2 MAP1B CCT5 CCT8 MACF1 ZNF318 PLXNB2 NNT TOP2A KRT80	6.87e-05	1024	75	10	24711643
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	PDXDC1 TRPM4 SUN2 BSDC1 ITGA6 COLGALT1 PLXNB2	6.89e-05	468	75	7	31056421
Pubmed	Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation.	CCT5 CCT8 KNL1	7.10e-05	37	75	3	26811472
Interaction	SOX2 interactions	SOX5 ATP6V1B1 ATP6V1B2 KMT2D KARS1 MAP1B CCT5 LGALSL SUN2 HNRNPM HELZ2 HIP1R CCT8 ANKRD17 MACF1 TRIM24 STOM KNL1	3.37e-06	1422	75	18	int:SOX2
Interaction	AGR2 interactions	PDXDC1 RTKN2 NRF1 CCT5 GLRX3 MCTS1 HNRNPM CCT8 MACF1 FH PGAM1 NNT STOM SORD	7.66e-06	934	75	14	int:AGR2
Interaction	CEBPA interactions	ZBTB34 KMT2D KARS1 CCT5 GLRX3 MCTS1 HNRNPM CCT8 PPME1 MACF1 ZNF318 TRIM24 PGAM1 TOP2A KNL1 SORD	1.09e-05	1245	75	16	int:CEBPA
Interaction	PGAM4 interactions	CCT5 CCT8 PGAM1 PGAM2	1.46e-05	40	75	4	int:PGAM4
Interaction	PPIA interactions	PDXDC1 STRN PTPRG MAP1B HNRNPM ASPM HIP1R MACF1 COLGALT1 PGAM2 TOP2A KNL1 SORD	2.17e-05	888	75	13	int:PPIA
Interaction	KRT38 interactions	GLRX3 ASPM ZNF318 SEPTIN10 TRIM24 KRT80	4.38e-05	172	75	6	int:KRT38
Interaction	GAPDH interactions	KARS1 MAP1B CCT5 TK1 PPME1 MACF1 COLGALT1 DRAP1 PGAM1 PGAM2 KNL1	4.43e-05	686	75	11	int:GAPDH
Interaction	PGK1 interactions	MAP1B ANKRD17 MACF1 ZNF318 FH TRIM24 PGAM1 TOP2A	6.53e-05	367	75	8	int:PGK1
Interaction	ALKBH3 interactions	MAP1B CCT5 GLRX3 CCT8	7.86e-05	61	75	4	int:ALKBH3
Interaction	CTTNBP2 interactions	STRN CCT5 CCT8 PPME1	8.38e-05	62	75	4	int:CTTNBP2
Interaction	SIRT7 interactions	KARS1 MAP1B CCT5 HELZ2 ANKRD17 MACF1 ZNF318 FH PGAM1 NNT TOP2A	9.17e-05	744	75	11	int:SIRT7
Interaction	EPRS1 interactions	ATP6V1B2 KARS1 MAP1B CCT5 HNRNPM CCT8 ODF2 SEPTIN10 STOM	1.18e-04	513	75	9	int:EPRS1
Interaction	HMOX2 interactions	ATP6V1B2 WIF1 MACF1 FH PLXNB2 NNT STOM	1.19e-04	297	75	7	int:HMOX2
GeneFamily	Bisphosphoglycerate phosphatases	PGAM1 PGAM2	4.66e-05	4	51	2	1082
GeneFamily	Chloride voltage-gated channels	CLCNKA CLCNKB	3.46e-04	10	51	2	302
GeneFamily	Chaperonins	CCT5 CCT8	8.00e-04	15	51	2	587
GeneFamily	V-type ATPases	ATP6V1B1 ATP6V1B2	1.90e-03	23	51	2	415
GeneFamily	Phosphoinositide phosphatases	FIG4 MTMR3	3.67e-03	32	51	2	1079
Coexpression	GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN	TK1 ASPM ALAS1 FH PGAM1 TOP2A SORD	1.74e-06	200	75	7	M5292
Coexpression	GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN	FOCAD TK1 ASPM ALAS1 FH PGAM1 TOP2A	1.74e-06	200	75	7	M5303
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	RTKN2 STRN NRF1 TK1 ASPM ITGA6 PGM2L1 ODF2 FH NNT TOP2A KNL1	1.36e-05	939	75	12	M45768
Coexpression	GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN	TK1 ASPM ALAS1 FH PGAM1 TOP2A	2.38e-05	200	75	6	M5300
Coexpression	GSE360_L_DONOVANI_VS_T_GONDII_DC_UP	CACNA1E KMT2D FIG4 APOBEC2 ODF2 PLXNB2	2.38e-05	200	75	6	M5195
Coexpression	HOWARD_NK_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_3DY_UP	TK1 ASPM TOP2A KNL1	4.38e-05	68	75	4	M41108
Coexpression	BUSSLINGER_ESOPHAGEAL_PROLIFERATING_BASAL_CELLS	TK1 ASPM ITGA6 TOP2A	4.91e-05	70	75	4	M40002
Coexpression	FAN_EMBRYONIC_CTX_NSC_2	RTKN2 TK1 ASPM ODF2 TOP2A KNL1	5.58e-05	233	75	6	M39036
Coexpression	TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP	CCT5 GLRX3 ASPM TOP2A	6.11e-05	74	75	4	M4479
Coexpression	REICHERT_MITOSIS_LIN9_TARGETS	ASPM TOP2A KNL1	6.26e-05	27	75	3	M2483
Coexpression	HEVNER_CORTICAL_PLATE_POSTMITOTIC_PROJECTION_NEURONS	SOX5 CACNA1E FIG4 ROBO1 PCDH9	6.52e-05	147	75	5	MM414
Coexpression	REICHERT_MITOSIS_LIN9_TARGETS	ASPM TOP2A KNL1	7.00e-05	28	75	3	MM1323
Coexpression	NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN	GPD1 CUX2 WIF1 HIP1R	7.14e-05	77	75	4	M17937
Coexpression	LIU_PROSTATE_CANCER_DN	PARP6 TPST1 MAP1B WIF1 ROBO1 NNT PCDH9 STOM	8.28e-05	493	75	8	M19391
Coexpression	TRAVAGLINI_LUNG_PROLIFERATING_MACROPHAGE_CELL	GPD1 CCT5 TK1 ASPM ALAS1 COLGALT1 FH SEPTIN10 TOP2A STOM KNL1	9.29e-05	968	75	11	M41693
Coexpression	GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP	HELZ2 ASPM PLXNB2 TOP2A KNL1	1.52e-04	176	75	5	M2981
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP	TK1 APOBEC2 ASPM TOP2A KNL1	2.02e-04	187	75	5	M2984
Coexpression	FUJII_YBX1_TARGETS_DN	CCT5 TK1 ASPM ODF2 TOP2A	2.39e-04	194	75	5	M14340
Coexpression	GSE20727_CTRL_VS_H2O2_TREATED_DC_DN	FIG4 SUN2 HIP1R COLGALT1 SORD	2.51e-04	196	75	5	M9243
Coexpression	GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP	TRPM4 CLCNKB MACF1 ZNF318 TRIM24	2.57e-04	197	75	5	M8983
Coexpression	GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_DN	TPST1 KARS1 CCT8 PCDHB1 TOP2A	2.69e-04	199	75	5	M6365
Coexpression	GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN	FOCAD FIG4 GLRX3 MCTS1 SORD	2.69e-04	199	75	5	M4243
Coexpression	GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_DN	RTKN2 TK1 GEMIN8 TOP2A KNL1	2.69e-04	199	75	5	M6205
Coexpression	GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN	ASPM ITGA6 SEPTIN10 PCDHB1 TOP2A	2.69e-04	199	75	5	M3070
Coexpression	GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP	TK1 HNRNPM CCT8 ALAS1 TRIM24	2.75e-04	200	75	5	M7611
Coexpression	GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP	TRPM4 KMT2D HELZ2 BSDC1 PGAM1	2.75e-04	200	75	5	M331
Coexpression	GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN	CCT5 MACF1 ZNF318 FH PGAM1	2.75e-04	200	75	5	M8302
Coexpression	GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN	TK1 ASPM FH PGAM1 TOP2A	2.75e-04	200	75	5	M5294
Coexpression	GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_UP	PDXDC1 SEPTIN10 TRIM24 NNT STOM	2.75e-04	200	75	5	M6618
Coexpression	GSE21063_WT_VS_NFATC1_KO_BCELL_DN	KCNT2 CCT5 ASPM ZNF318 NNT	2.75e-04	200	75	5	M8261
Coexpression	BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP	ASPM SEPTIN10 TOP2A	3.13e-04	46	75	3	M7603
Coexpression	HORIUCHI_WTAP_TARGETS_DN	MAP1B TK1 ASPM SEPTIN10 TOP2A KNL1	3.14e-04	320	75	6	M10279
Coexpression	GAO_LARGE_INTESTINE_24W_C2_MKI67POS_PROGENITOR	TK1 ASPM HSPA12B TOP2A	3.14e-04	113	75	4	M39153
CoexpressionAtlas	Stem Cells, SC.MDP.BM, Sca1- Flt3+ MCSFR+ cKithi, Bone marrow, avg-3	TK1 ASPM ALAS1 FH PLXNB2 TOP2A STOM KNL1 SORD	1.07e-05	402	74	9	GSM791105_500
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NRF1 SUN2 HNRNPM ASPM ODF2 TOP2A KNL1	1.68e-08	172	75	7	7f3d0ef18f5df1ed80498d435b0378ca398c0b88
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RTKN2 TK1 SUN2 ASPM ODF2 TOP2A KNL1	3.59e-08	192	75	7	026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell	LA\|World / Chamber and Cluster_Paper	SOX5 CACNA1E TPST1 HMCN2 MAP1B GLI2 ROBO1	3.72e-08	193	75	7	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 TK1 SUN2 ASPM ODF2 TOP2A KNL1	4.43e-08	198	75	7	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 TK1 SUN2 ASPM ODF2 TOP2A KNL1	4.43e-08	198	75	7	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM PGAM2 TOP2A KNL1	2.71e-07	157	75	6	1ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	TK1 ITGA6 PGM2L1 NNT TOP2A KNL1	8.28e-07	190	75	6	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RTKN2 TK1 SUN2 ASPM TOP2A KNL1	8.80e-07	192	75	6	27723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	CCT5 TK1 ASPM CCT8 TOP2A KNL1	1.05e-06	198	75	6	880f9817f5145f10f29fc05c5866090433532fe2
ToppCell	15-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	RTKN2 TK1 SUN2 ASPM TOP2A KNL1	1.08e-06	199	75	6	5c8b847b794b3e88722f5b841f2539a27251106c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 TK1 ASPM ODF2 TOP2A KNL1	1.08e-06	199	75	6	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	COVID-19_Severe-immature_Neutrophil\|COVID-19_Severe / Disease condition and Cell class	LGALSL TK1 ASPM TOP2A STOM KNL1	1.08e-06	199	75	6	f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCell	COVID-19_Severe-immature_Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	LGALSL TK1 ASPM TOP2A STOM KNL1	1.08e-06	199	75	6	42ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNT2 PTPRG WIF1 ROBO1 PCDH9 STOM	1.12e-06	200	75	6	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Proliferating\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 TK1 ASPM SEPTIN10 TOP2A KNL1	1.12e-06	200	75	6	9279415f5e76cb5b4e071c6582ac249b72dd694c
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Proliferating-Cycling\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 TK1 ASPM SEPTIN10 TOP2A KNL1	1.12e-06	200	75	6	d582385b2dbb25eeba1b22c5d258a8f26a40ef8b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TK1 ASPM PCDHB1 TOP2A KNL1	2.35e-06	126	75	5	8ae631694bbba40f64e55e2be8162d7a40eeadc5
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TK1 GLI2 ASPM TOP2A KNL1	2.74e-06	130	75	5	169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TRIM16 VIL1 UNC45B HELZ2 HSPA12B	5.33e-06	149	75	5	d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCell	E16.5-samps\|World / Age Group, Lineage, Cell class and subclass	KARS1 ROBO1 PGAM1 TOP2A SORD	5.33e-06	149	75	5	e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TRIM16 VIL1 UNC45B HELZ2 HSPA12B	6.26e-06	154	75	5	b0735365de153d4586ca17896431d7bd9c7d8eac
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FOCAD KCNT2 APOBEC2 WIF1 ROBO1	6.46e-06	155	75	5	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	COVID-19_Severe-multiplets\|World / disease group, cell group and cell class	CACNA1E HMCN2 TK1 ASPM TOP2A	8.25e-06	163	75	5	6db4271c2d47a9c333964f36d2c32207115e52cd
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	VIL1 TK1 ASPM TOP2A KNL1	8.50e-06	164	75	5	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	9.02e-06	166	75	5	2642544070564debe2deb2938d2c33997bf5ef02
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	9.83e-06	169	75	5	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ATP6V1B1 PTPRG CLCNKA CLCNKB ROBO1	1.01e-05	170	75	5	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B GLI2 ASPM TOP2A KNL1	1.04e-05	171	75	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RTKN2 ASPM ODF2 TOP2A KNL1	1.04e-05	171	75	5	05014cf6746e6663e376fdd681f1b43a7081c603
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B GLI2 ASPM TOP2A KNL1	1.04e-05	171	75	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RTKN2 ASPM ODF2 TOP2A KNL1	1.04e-05	171	75	5	d6114db2292fbb27b39d090d51fd305a135b1ccf
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTKN2 TK1 ASPM TOP2A KNL1	1.07e-05	172	75	5	35c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TK1 ASPM CFAP74 TOP2A KNL1	1.07e-05	172	75	5	6fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRN TK1 ASPM TOP2A KNL1	1.07e-05	172	75	5	e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	1.10e-05	173	75	5	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP6V1B1 TK1 ASPM TOP2A KNL1	1.13e-05	174	75	5	46cbb462173a684ceb9e680f9259dc3b133763f7
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRF1 SUN2 ASPM ODF2 TOP2A	1.13e-05	174	75	5	1779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZBTB34 ASPM PLXNB2 TOP2A KNL1	1.16e-05	175	75	5	15c69dd5635c9251c535f1e22467712e9667ae92
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RTKN2 TK1 ASPM TOP2A KNL1	1.20e-05	176	75	5	b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	1.23e-05	177	75	5	75049e5372d14edeb5768339359396b73a85c2cc
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RTKN2 SUN2 ASPM TOP2A KNL1	1.30e-05	179	75	5	6718cadcc2d3b64717ed84244ef1242d392662dc
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCT5 TK1 ASPM TOP2A KNL1	1.33e-05	180	75	5	44988c34861df359a68376500c42a64fbcc4b431
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	1.33e-05	180	75	5	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SUN2 ASPM ODF2 TOP2A KNL1	1.33e-05	180	75	5	ed4966765a6b25456f68185cf0648c4a3a21d7fe
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TK1 APOBEC2 ASPM TOP2A KNL1	1.37e-05	181	75	5	cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TK1 APOBEC2 ASPM TOP2A KNL1	1.37e-05	181	75	5	74311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	TK1 ASPM TOP2A KRT80 KNL1	1.37e-05	181	75	5	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASPM ALAS1 SEPTIN10 TOP2A KNL1	1.41e-05	182	75	5	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASPM ALAS1 SEPTIN10 TOP2A KNL1	1.41e-05	182	75	5	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TK1 APOBEC2 ASPM TOP2A KNL1	1.44e-05	183	75	5	769a022fe8568ec49e66f792cc5777e713a7571c
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TK1 APOBEC2 ASPM TOP2A KNL1	1.44e-05	183	75	5	aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HMCN2 KCNT2 MAP1B ROBO1 PCDH9	1.52e-05	185	75	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	1.52e-05	185	75	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1E CUX2 LRFN1 MAP1B HIP1R	1.52e-05	185	75	5	edb114487206e4e8df4c7878285df40f49b7fd64
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTKN2 TK1 ASPM TOP2A KNL1	1.56e-05	186	75	5	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VIL1 MAP1B UNC45B ITGA6 STOM	1.56e-05	186	75	5	b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VIL1 MAP1B UNC45B ITGA6 STOM	1.56e-05	186	75	5	8a8ed1502542d4895cba3fd5d534256206578716
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FOCAD SOX5 MAP1B WIF1 ROBO1	1.56e-05	186	75	5	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTKN2 TK1 ASPM TOP2A KNL1	1.56e-05	186	75	5	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TK1 GLI2 ASPM TOP2A KNL1	1.60e-05	187	75	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TK1 GLI2 ASPM TOP2A KNL1	1.60e-05	187	75	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	1.60e-05	187	75	5	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CACNA1E TK1 ASPM TOP2A KNL1	1.64e-05	188	75	5	ecba5d06cbf3254448255a2aeefffe711f43310e
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CCT5 TK1 ASPM TOP2A KNL1	1.64e-05	188	75	5	15146fd2c5592ea84d20b1fdd172b39cd60b5bed
ToppCell	NS-critical-d_0-4-Lymphoid-NKT-proliferating\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TK1 ASPM PCDH9 TOP2A KNL1	1.69e-05	189	75	5	d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 KCNT2 MAP1B UNC45B GLI2	1.69e-05	189	75	5	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RTKN2 TK1 ASPM TOP2A KNL1	1.69e-05	189	75	5	fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 KCNT2 MAP1B UNC45B GLI2	1.69e-05	189	75	5	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VIL1 MAP1B UNC45B ITGA6 STOM	1.69e-05	189	75	5	2e43428f1ef9683c6f8c9897d46aa7d34bf9047f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TK1 ASPM TOP2A KNL1 TXK	1.73e-05	190	75	5	185ae04c68f825cd346aa65072cc5da6a39dff4a
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo\|lymph-node_spleen / Manually curated celltypes from each tissue	TK1 ASPM TOP2A STOM KNL1	1.73e-05	190	75	5	4225bfa10a6fb909a3ba8ac26f3541c390b46737
ToppCell	Severe-Lymphoid-T-NK\|Severe / Condition, Lineage, Cell class and cell subclass	TK1 ASPM TOP2A KNL1 TXK	1.73e-05	190	75	5	60642de433f84fa2cecd796c3a1a4aab9219d3db
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TK1 ASPM TOP2A KNL1 TXK	1.73e-05	190	75	5	b65383e256b04122500b742caeed0b807793851e
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TK1 SUN2 ASPM TOP2A KNL1	1.73e-05	190	75	5	cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TK1 ASPM TOP2A KNL1 TXK	1.73e-05	190	75	5	89095d3e023269d89c82e3a73550f869e3f34201
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RTKN2 TK1 ASPM TOP2A KNL1	1.73e-05	190	75	5	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TK1 ASPM TOP2A KNL1 TXK	1.73e-05	190	75	5	e38dc41f2e79e3bd51326581c6ebe51927edb549
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RTKN2 WIF1 ASPM TOP2A KNL1	1.77e-05	191	75	5	39220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TK1 ASPM ITGA6 TOP2A KNL1	1.77e-05	191	75	5	0f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RTKN2 SUN2 ASPM TOP2A KNL1	1.77e-05	191	75	5	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RTKN2 WIF1 ASPM HIP1R ITGA6	1.82e-05	192	75	5	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RTKN2 SUN2 ASPM TOP2A KNL1	1.82e-05	192	75	5	0a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 KCNT2 MAP1B GLI2 ROBO1	1.82e-05	192	75	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	Non-neuronal-Dividing-Radial_Glia-Low_Quality-16\|World / Primary Cells by Cluster	RTKN2 TK1 HNRNPM ASPM TOP2A	1.82e-05	192	75	5	0d6413df15dfecdffc777fb02df3aaf0c30540b1
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM16 PTPRG UNC45B ITGA6 HSPA12B	1.82e-05	192	75	5	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM16 PTPRG UNC45B ITGA6 HSPA12B	1.82e-05	192	75	5	a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell	Non-neuronal-Dividing-Radial_Glia-Low_Quality\|World / Primary Cells by Cluster	RTKN2 TK1 HNRNPM ASPM TOP2A	1.82e-05	192	75	5	5fa5b2f250ec5ad5a232c022266f0cd01ff4a753
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM16 PTPRG UNC45B ITGA6 HSPA12B	1.82e-05	192	75	5	66defad13bd8e79319741e43ddb056841710b1d7
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TK1 ASPM ROBO1 TOP2A KNL1	1.87e-05	193	75	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	SOX5 KCNT2 PTPRG MAP1B ROBO1	1.87e-05	193	75	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	control-Myeloid-Immature_Neutrophils_2\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TK1 ASPM TOP2A STOM KNL1	1.87e-05	193	75	5	33349830e9eba506470ad3661fad5e5a283d20ca
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	TK1 ASPM TOP2A STOM KNL1	1.91e-05	194	75	5	4a207630d72059345b10010f5cfd3b1462458324
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RTKN2 ASPM HIP1R TOP2A KNL1	1.91e-05	194	75	5	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RTKN2 TK1 ASPM TOP2A KNL1	1.91e-05	194	75	5	1a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RTKN2 TK1 ASPM TOP2A KNL1	1.91e-05	194	75	5	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SOX5 PTPRG GLI2 MACF1 ROBO1	1.91e-05	194	75	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	wk_15-18-Hematologic_Lymphocytic-NK-Cycling_NK\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TK1 ASPM TOP2A KNL1 TXK	1.91e-05	194	75	5	af08047e5728ee8198d2686af6a774f2acfa58ba
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TK1 ASPM TOP2A KNL1 TXK	1.91e-05	194	75	5	6cc689595a182fbf685fa2f3b9c300f7170fb81f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 KCNT2 MAP1B GLI2 ROBO1	1.91e-05	194	75	5	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 KCNT2 MAP1B GLI2 ROBO1	1.91e-05	194	75	5	df82cce5ebeb73740b02cf816c6df82253cfd566
Computational	Genes upregulated in subsets of cells of a given type within various tumors	ATP6V1B1 CLCNKA CLCNKB ITGA6	1.03e-04	50	53	4	GAVISH_3CA_METAPROGRAM_EPITHELIAL_V_ATPASE
Disease	Bartter disease type 4B	CLCNKA CLCNKB	5.71e-06	2	71	2	cv:C4310805
Disease	BARTTER SYNDROME, TYPE 4B	CLCNKA CLCNKB	5.71e-06	2	71	2	C2751312
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	5.71e-06	2	71	2	C4310805
Disease	Bartter disease type 3 (implicated_via_orthology)	CLCNKA CLCNKB	5.71e-06	2	71	2	DOID:0110144 (implicated_via_orthology)
Disease	Bartter disease type 4b (is_implicated_in)	CLCNKA CLCNKB	5.71e-06	2	71	2	DOID:0110146 (is_implicated_in)
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	5.71e-06	2	71	2	613090
Disease	Bartter disease (implicated_via_orthology)	CLCNKA CLCNKB	5.71e-06	2	71	2	DOID:445 (implicated_via_orthology)
Disease	follicular lymphoma (implicated_via_orthology)	ATP6V1B1 ATP6V1B2	5.68e-05	5	71	2	DOID:0050873 (implicated_via_orthology)
Disease	depressive symptom measurement	SOX5 CACNA1E PTPRG TSNARE1 ROBO1 ALAS1 PCDH9	7.47e-05	426	71	7	EFO_0007006
Disease	quality of life during menstruation measurement, breast pressure measurement	MAP1B ANKRD17	8.51e-05	6	71	2	EFO_0009366, EFO_0009393
Disease	Bartter syndrome	CLCNKA CLCNKB	8.51e-05	6	71	2	cv:C0004775
Disease	renal tubular acidosis (implicated_via_orthology)	ATP6V1B1 ATP6V1B2	1.58e-04	8	71	2	DOID:14219 (implicated_via_orthology)
Disease	Seizures	CACNA1E CUX2 KARS1 MACF1 FH	1.84e-04	218	71	5	C0036572
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	CLCNKA CLCNKB	2.54e-04	10	71	2	DOID:12387 (implicated_via_orthology)
Disease	Lymphoma, Large-Cell, Follicular	ATP6V1B2 KMT2D	5.87e-04	15	71	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	ATP6V1B2 KMT2D	5.87e-04	15	71	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	ATP6V1B2 KMT2D	5.87e-04	15	71	2	C0079758
Disease	Lymphoma, Follicular, Grade 2	ATP6V1B2 KMT2D	5.87e-04	15	71	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	ATP6V1B2 KMT2D	5.87e-04	15	71	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	ATP6V1B2 KMT2D	5.87e-04	15	71	2	C1956130
Disease	Autosomal recessive primary microcephaly	ASPM KNL1	5.87e-04	15	71	2	cv:C3711387
Disease	unipolar depression	SOX5 CACNA1E ZBTB34 ATP6V1B2 KCNT2 PTPRG FIG4 ROBO1 FH PCDH9	6.00e-04	1206	71	10	EFO_0003761
Disease	creatinine measurement	SOX5 VIL1 ATP6V1B1 CUX2 NRF1 MTMR3 FH PLXNB2 SORD	6.21e-04	995	71	9	EFO_0004518
Disease	primary autosomal recessive microcephaly (is_implicated_in)	ASPM KNL1	6.70e-04	16	71	2	DOID:0070296 (is_implicated_in)
Disease	urate measurement, bone density	ATP6V1B1 STRN PTPRG GLI2 HELZ2 ROBO1 SEPTIN10	7.20e-04	619	71	7	EFO_0003923, EFO_0004531
Disease	body surface area	PDXDC1 SOX5 PTPRG LGALSL GLI2 MTMR3 MACF1	8.99e-04	643	71	7	EFO_0022196
Disease	stroke, major depressive disorder	SOX5 PTPRG	9.51e-04	19	71	2	EFO_0000712, MONDO_0002009
Disease	Lymphoma, Follicular	ATP6V1B2 KMT2D	1.05e-03	20	71	2	C0024301
Disease	Malignant neoplasm of breast	KMT2D KCNT2 CCT5 UNC45B MTMR3 MACF1 ROBO1 ZNF318 TOP2A	1.07e-03	1074	71	9	C0006142
Disease	Primary microcephaly	ASPM KNL1	1.28e-03	22	71	2	C0431350
Disease	Autosomal Recessive Primary Microcephaly	ASPM KNL1	1.28e-03	22	71	2	C3711387
Disease	wellbeing measurement	SOX5 CACNA1E RTKN2 PTPRG TSNARE1 ALAS1 PCDH9	1.37e-03	692	71	7	EFO_0007869
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	KMT2D FH	1.40e-03	23	71	2	C1708353
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	FIG4 MTMR3	1.52e-03	24	71	2	DOID:10595 (implicated_via_orthology)
Disease	brain measurement, neuroimaging measurement	PDXDC1 SOX5 ZBTB34 STRN MACF1 ROBO1	2.10e-03	550	71	6	EFO_0004346, EFO_0004464

Protein segments in the cluster

Peptide	Gene	Start	Entry
MTVDKNGAVLIADES	PTPRG	1421	P23470
EAGVTDEVLDSAMQA	TPST1	126	O60507
EEVMLAEENKNAGTS	CACNA1E	391	Q15878
EEVQMALSKVDASGE	BSDC1	406	Q9NW68
MEKATVPVAAATAAE	ANKRD17	1	O75179
VAKAMGAAQVVVTDL	SORD	191	Q00796
EAASKADEVGLIMTN	CUX2	231	O14529
KSDGSMEDANVRVAI	ASPM	576	Q8IZT6
MAQKEEAAVATEAAS	APOBEC2	1	Q9Y235
MQTDEEIGKVAAAVP	DRAP1	21	Q14919
LSAETMAKDVGNVVE	PPME1	126	Q9Y570
AEEMESGSFVANVAK	PCDHB1	36	Q9Y5F3
MAGSVADSDAVVKLD	LGALSL	1	Q3ZCW2
AVAGNAAVMAVIAKT	GPR61	56	Q9BZJ8
MAVVDKAAEAGGAEE	MAP1B	1046	P46821
AAVDTIVAIMAEGKQ	MCTS1	126	Q9ULC4
GDSAAKIQAMEAAVQ	GEMIN8	206	Q9NWZ8
EMNAVRKEVAETSAG	ALAS1	136	P13196
MAAGAAEAAVAAVEE	GLRX3	1	O76003
EMSVGAIKAAVEVAN	HMCN2	116	Q8NDA2
APAVAVEAKAMEAET	LRFN1	616	Q9P244
MAAGVEAAAEVAATE	HNRNPM	1	P52272
DLAAQVKDVSVTVGM	KRT80	226	Q6KB66
KAMTLQEAEAFVGAE	PLXNB2	1121	O15031
VVAEVFAVDVDTGMN	PCDH9	696	Q9HC56
LDKDGVSAAVVVAEM	PGM2L1	446	Q6PCE3
VGMASDNVDAAELVE	PDXDC1	576	Q6P996
DSAVTMDGQAVEVVT	NRF1	486	Q16656
VEEKRVDVNSAVAMG	MACF1	2946	O94854
VDVNSAVAMGEVILA	MACF1	2951	O94854
AAMDEKVIGKVVDQA	KNL1	1276	Q8NG31
ISENVAMEAVAAGVD	GLI2	1031	P10070
GTVVGEQAMKSEDEV	ITGA6	851	P23229
GVTFAANMVVVDKES	KCNT2	791	Q6UVM3
AMQFGDTEIKVTAVD	HSPA12B	656	Q96MM6
AMANAGKTVIVAALD	TK1	111	P04183
EKRVDVNSAVAMGEV	MACF1	6821	Q9UPN3
QEELGAVVDKEMAAT	HIP1R	776	O75146
MTDAGDSAKVTENVV	FIG4	781	Q92562
IANAIMKAADEVAEG	FH	116	P07954
VLMGANIASEVADEK	GPD1	146	P21695
LVEAVDGKAMNTSQV	COLGALT1	371	Q8NBJ5
VGDLAEEQAAVVTAM	HELZ2	981	Q9BYK8
EEQAAVVTAMVKAEP	HELZ2	986	Q9BYK8
AEIATEEEAGNMAAV	CFAP74	121	Q9C0B2
EETVRKAMEAVAAQG	PGAM1	236	P18669
AGIIEATEAEDVMNK	FOCAD	1201	Q5VW36
AELSVAAGVAEGQME	MTMR3	676	Q13615
MSGAAEEVATGAEVV	PARP6	321	Q2NL67
LVEAEMDGAAAAKQV	ODF2	211	Q5BJF6
SMKEGSVVVDLAAEA	NNT	336	Q13423
MGANVFDTDVVNVDK	RTKN2	136	Q8IZC4
DVQAMKAVVGEEALT	ATP6V1B2	431	P21281
VQAMKAVVGEEALTS	ATP6V1B1	426	P15313
VNGTEAEVKETAMIA	STRN	206	O43815
MAAVQAAEVKVDGSE	KARS1	1	Q15046
EETVRKAMEAVAAQG	PGAM2	236	P15259
MVDKDGDVTVTNDGA	CCT5	61	P48643
EARAKVIAAEGEMNA	STOM	216	P27105
KQNEMLVAAAAVGVA	CLCNKA	196	P51800
KQNEMLVAAAAVGVA	CLCNKB	196	P51801
DDDKVQNAAAGALAM	UNC45B	816	Q8IWX7
VAAQQKMVDDGSGEV	VIL1	386	P09327
MEVAVEKAVAAAAAA	TRIM24	1	O15164
KDLASMVSEQGEAVD	TSNARE1	441	Q96NA8
VAEMQGKSAREAAAS	SUN2	496	Q9UH99
GVAAFEVDVIVMNSE	WIF1	146	Q9Y5W5
VAENMVGKAEASATL	ROBO1	331	Q9Y6N7
TDDDTIAKVNAAMNG	SEPTIN10	241	Q9P0V9
EVKVAQLAGSVAEMS	TOP2A	741	P11388
VAIKAINEGSMSEED	TXK	296	P42681
VSVSEVKAVAEMQFG	TRIM16	206	O95361
ADGEVAMVTSRQKVE	SOX5	26	P35711
MDAQVKAIADTGANV	CCT8	276	P50990
AAFASEIENKGTMVE	ZNF318	426	Q5VUA4
AVAMEDAFGAAVVTV	TRPM4	46	Q8TD43
VEQKLENDASASEMG	ZBTB34	471	Q8NCN2
AAAKNLNGVMVAVAE	KMT2D	4791	O14686